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[analysis on volatile components of ficus carica fruit].to analyze the volatile chemical components of ficus carica fruits.201425566658
ethnomedicinal values, phenolic contents and antioxidant properties of wild culinary vegetables.traditional medicines comprise a variety of health practices, approaches, knowledge, and beliefs. documentation of traditional knowledge, estimation of total phenolics and antioxidant properties of plant species used as wild vegetables and in traditional medicines by the local communities of lesser himalayas-pakistan are targeted.201525571845
effects of cream containing ficus carica l. fruit extract on skin parameters: in vivo evaluation.this study was aimed to investigate the effects of cream containing ficus carica l. fruit (fig) extract on various skin parameters such as skin melanin, erythema, moisture content, trans-epidermal water loss and sebum. for this purpose, formulation with 4% concentrated extract of f. carica fruit and base without extract were developed. base served as a control. both base and formulation were applied to the cheeks of human volunteers for 8 weeks to investigate the effects on different skin parame ...201725593393
characterisation of general proteolytic, milk clotting and antifungal activity of ficus carica latex during fruit ripening.the physiological role of fig latex is to protect the plant from pathogens. latex is a rich source of proteases, predominantly ficin. fig latex also contains collagenolytic protease and chitinolytic enzymes. our aim was to investigate changes in protein composition, enzyme and antifungal activities of fig latex during fruit ripening.201625664689
evaluation of general toxicity, anti-oxidant activity and effects of ficus carica leaves extract on ischemia/reperfusion injuries in isolated heart of rat.this study was aimed to evaluate general toxicity, anti-oxidant activity and effects of ficus carica leaves extract on ischemia/reperfusion injuries.201425671192
tirucallane-type triterpenoids from the fruit of ficus carica and their cytotoxic activity.nine new tirucallane-type triterpenoids, ficutirucins a-i (1-9), were isolated from the fruit of ficus carica. their structures were established on the basis of spectroscopic data and chemical methods. all isolates were evaluated for their cytotoxic activities against three human cancer cell lines, mcf-7, hepg-2, and u2os. compounds 1-3, 6, 7, and 9 exhibited moderate cytotoxic activities with ic50 values of 11.67-45.61 µm against one or more of the three cancer cell lines.201525757495
caprine herpesvirus 1 (cphv-1) vaginal infection of goats: clinical efficacy of fig latex.the latex of ficus carica linn. (moraceae) has been shown to interfere with the replication of caprine herpesvirus (cphv)-1 in vitro. the present study was undertaken to determine the efficacy of vaginal administration of fig latex in goats experimentally infected with cphv-1. the fig latex reduced the clinical signs of the herpetic disease although it slightly influenced the titres of cphv-1 shed. thus, the fig latex maintained a partial efficacy in vivo.201625835328
crystallization and preliminary x-ray analysis of four cysteine proteases from ficus carica latex.the latex of the common fig (ficus carica) contains a mixture of at least five cysteine proteases commonly known as ficins (ec 3.4.22.3). four of these proteases were purified to homogeneity and crystals were obtained in a variety of conditions. the four ficin (iso)forms appear in ten different crystal forms. all diffracted to better than 2.10 å resolution and for each form at least one crystal form diffracted to 1.60 å resolution or higher. ficin (iso)forms b and c share a common crystal form, ...201525849510
the ambiguous ripening nature of the fig (ficus carica l.) fruit: a gene-expression study of potential ripening regulators and ethylene-related genes.the traditional definition of climacteric and non-climacteric fruits has been put into question. a significant example of this paradox is the climacteric fig fruit. surprisingly, ripening-related ethylene production increases following pre- or postharvest 1-methylcyclopropene (1-mcp) application in an unexpected auto-inhibitory manner. in this study, ethylene production and the expression of potential ripening-regulator, ethylene-synthesis, and signal-transduction genes are characterized in figs ...201525956879
trnaleu intron (uaa) of ficus carica l.: genetic diversity and evolutionary patterns.cytoplasmic chloroplast dna was explored to establish genetic relationships among ficus carica cultivars and elucidate the molecular evolution of the species. the results suggest the occurrence of haplotype and nucleotide diversity. conserved group i intron sequence motifs were detected and showed a common secondary structure, despite the presence of some mutations on their sequences. the neighbor-joining dendrogram showed a continuous diversity that characterizes local resources. the maximum pa ...201525966152
methanolic extract of ficus carica linn. leaves exerts antiangiogenesis effects based on the rat air pouch model of inflammation.the antiangiogenesis effect of ficus carica leaves extract in an air pouch model of inflammation was investigated in rat. inflammation was induced by injection of carrageenan into pouches. after antioxidant capacity and total phenolic content (tpc) investigations, the extract was administered at 5, 25, and 50 mg/pouch, and then the volume of exudates, the cell number, tnfα, pge2, and vegf levels were measured. angiogenesis of granulation tissues was determined by measuring hemoglobin content. ba ...201525977699
a novel form of ficin from ficus carica latex: purification and characterization.a novel ficin form, named ficin e, was purified from fig tree latex by a combination of cation-exchange chromatography on sp-sepharose fast flow, thiopropyl sepharose 4b and fplc-gel filtration chromatography. the new ficin appeared not to be sensitive to thiol derivatization by a polyethylene glycol derivative, allowing its purification. the protease is homogeneous according to page, sds-page, mass spectrometry, n-terminal micro-sequencing analyses and e-64 active site titration. n-terminal seq ...201526083455
preservation of different fig cultivars (ficus carica l.) under modified atmosphere packaging during cold storage.the effect of modified atmosphere packaging (map) on the stability of 'cuello dama blanco' (cdb), 'cuello dama negro' (cdn) and 'san antonio' (sa) figs during post-harvest cold storage was evaluated by using three different films with a diverse number of microperforations (diameter, ø = 100 µm): m10 (16 holes), m30 (five holes) and m50 (three holes). a macroperforated film was used as control (five holes, ø = 9 mm). gas composition, weight loss, percentage disorder, microbial counts and physico- ...201626124078
in vitro antioxidant, collagenase inhibition, and in vivo anti-wrinkle effects of combined formulation containing punica granatum, ginkgo biloba, ficus carica, and morus alba fruits extract.in phytotherapy, the therapeutic potential is based on the combined action of different herbal drugs. our objective was to evaluate the antioxidant, anti-collagenase (in vitro), and anti-wrinkle (in vivo) effect of combined formulation containing ginkgo biloba, punica granatum, ficus carica, and morus alba fruits extract.201526203268
characterization of free and conjugated phenolic compounds in fruits of selected wild plants.a gas chromatography-mass spectrometric (gc-ms) method was utilized for the separation, and systematic characterization of phenolic compounds as trimethylsilyl derivatives in fruits of wild plants including olive, jujube and common fig. both the free and conjugate phenolic acids (rarely determined before and several are reported first time here) were characterized. a baseline separation of the 20 phenolics was achieved in 25 min with standard calibration curves linear over the concentration rang ...201626212944
ethanolic extract of ficus carica leave suppresses angiogenesis by regulating vegf-a and integrin β3 mrna expression in human umbilical vein endothelial cells.in the present study, we investigated the anti-angiogenic effects of the ethanol extract of ficus carica leave on human umbilical vein endothelial cells (huvecs).201526215010
natural products of relevance in the prevention and supportive treatment of depression.the use of herbs or their parts: leaves, roots, rhizomes, flowers, seeds, natural strains, as well as extracts or isolated metabolites is becoming more and more popular. natural remedies not only act prophylactically, but also help to alleviate symptoms of many diseases and enhance the overall functioning of the internal organs. many raw materials of natural origin plays a role in treatment of health problems, and also in case of serious diseases such as depression. depression (affective disorde ...201626276913
fig (ficus carica) liquid co-products as new potential functional ingredient: physico-chemical and in vitro antioxidant properties.the aims of this study were to determine (i) the physico-chemical characteristics, (ii) the phenolic, flavonoid and anthocyanins profile, (iii) the organic acids and sugar content, and (iv) the antioxidant properties of the liquid co-product generated by the figs (flc) processing industry in order to set standards for its applications as a potential ingredient of food products. the liquid co-products obtained from the peel and pulp of two fig varieties (colar and cuello de dama) were used. the p ...201526411015
the effect of ficus carica l. (anjir) leaf extract on gentamicin induced nephrotoxicity in adult male albino mice.gentamicin is an aminoglycoside isolated from micromonospora purpurea known for its nephrotoxicity. ficus carica l is known to treat many ailments. this study was designed to investigate the effects of ficus carica l. (anjir) leaf extract on renal oxidative stress induced by gentamicin in albino mice.201526411127
two nematicidal furocoumarins from ficus carica l. leaves and their physiological effects on pine wood nematode (bursaphelenchus xylophilus).the ethanol extract of the ficus carica l. leaves was tested to show strong nematicidal activity against pine wood nematode (pwn), bursaphelenchus xylophilus, causing 90.93% corrected mortality within 72 h at 1.0 mg/ml. from the ethyl acetate soluble fraction of the f. carica l. leaves extract, the main nematicidal constituents were obtained by bioassay-guided isolation and identified as linear furocoumarins bergapten (1) and psoralen (2) by mass and nmr spectral data analysis. bergapten and pso ...201626479900
bacterial quorum sensing inhibition activity of the traditional chinese herbs, ficus carica l. and perilla frutescens.quorum sensing (qs), as the basis of bacterial cell-to-cell communication, is a promising approach to reduce the incidence of multidrug resistance. the objective of this study was to search for novel quorum sensing inhibitors from plants and control detrimental infections.201426496663
characterization of fig achenes' oil of ficus carica grown in tunisia.this work investigated the composition of the oil extract from achenes of "kholi" variety of ficus carica, grown in tunisia. fatty acid and sterol compositions were analyzed by gas chromatography (gc) coupled to flame ionization detector (fid). furthermore, the antioxidant capacity in fig achenes' oil was assessed by employing two different in vitro assays such as dpph, abts(+) radical scavenging capacities. our results indicated that the fig achenes' oil is a rich source of bioactive molecules. ...201626593597
quantitative analysis of biomarker rutin in different species of genus ficus by validated np and rp-hptlc methods.biomarker rutin was analyzed in methanol extracts of leaves of five different species of genus ficus (ficus carica, ficus nitida, ficus ingens, ficus palmata and ficus vasta) by np-hptlc (method i) and rp- hptlc methods (method ii). the development and validation for method i was carried out with silica gel 60f254 plates using ea: gaa: fa: h2o (10:1:1:2.5, v/v/v/v) as developing system. method ii was carried out on silica gel 60f254 rp-18 plates using mobile phase acn: h2o (4:6 v/v). both analys ...201526687740
ala pretreatment improves waterlogging tolerance of fig plants.5-aminolevulinic acid (ala), a natural and environmentally friendly plant growth regulator, can improve plant tolerance to various environmental stresses. however, whether ala can improve plant waterlogging tolerance is unknown. here, we investigated the effects of ala pretreatment on the waterlogging-induced damage of fig (ficus carica linn.) plants, which often suffer from waterlogging stress. ala pretreatment significantly alleviated stress-induced morphological damage, increased leaf relativ ...201626789407
the effect of the hexanic extracts of fig (ficus carica) and olive (olea europaea) fruit and nanoparticles of selenium on the immunogenicity of the inactivated avian influenza virus subtype h9n2.influenza is a contagious viral disease that is seen in avian, human and other mammals, so its control is important. vaccination against influenza virus subtype h9n2 is one of the ways in controlling program, for this reason several vaccines has been produced. recently, application of inactivated oil-emulsion vaccines in poultry for controlling low pathogenic avian influenza is increasing. at present, oils that are used as adjuvant in commercial vaccines are mineral oils, which not only lack imm ...201526893813
effects of common fig (ficus carica) leaf extracts on sperm parameters and testis of mice intoxicated with formaldehyde.formaldehyde (fa) is the leading cause of cellular injury and oxidative damage in testis that is one of the main infertility causes. there has been an increasing evidence of herbal remedies use in male infertility treatment. this assay examines the role of ficus carica (fc) leaf extracts in sperm parameters and testis of mice intoxicated with fa. twenty-five adult male mice were randomly divided into control; sham; fa-treated (10 mg/kg twice per day); fc-treated (200 mg/kg); and fa + fc-treated ...201626904140
yeasts isolated from figs (ficus carica l.) as biocontrol agents of postharvest fruit diseases.fresh fruit is highly perishable during postharvest life, mainly due to fungal growth. thus, fungal control is an important goal for the fruit industry. in this work, a selection of antagonistic yeasts isolated from fig and breba crops were screened in vitro. the isolated yeasts were challenged with three moulds isolated from decayed figs and breba crops, identified as penicillium expansum m639 and cladosporium cladosporioides m310 and m624, and pathogenic moulds botrytis cinerea cect20518 and m ...201627052701
antihyperlipidemic and antioxidant activities of edible tunisian ficus carica l. fruits in high fat diet-induced hyperlipidemic rats.the phenolic constituents of the aqueous-ethanolic extract of tunisian ficus carica (f. carica) fruit (fe) and its antihyperlipidemic and antioxidant activities in high-fat diet-induced hyperlipidemic rats (hfd) were evaluated. the obtained results demonstrated that the fe improved the lipid profile by decreasing the total cholesterol, triglyceride, low-density lipoprotein cholesterol and increasing high-density lipoprotein cholesterol levels. it also reduced the content of thiobarbituric acid-r ...201627086310
chlorophyll metabolism in pollinated vs. parthenocarpic fig fruits throughout development and ripening.expression of 13 genes encoding chlorophyll biosynthesis and degradation was evaluated. chlorophyll degradation was differentially regulated in pollinated and parthenocarpic fig fruits, leading to earlier chlorophyll degradation in parthenocarpic fruits. varieties of the common fig typically yield a commercial summer crop that requires no pollination, although it can be pollinated. fig fruit pollination results in larger fruit size, greener skin and darker interior inflorescence color, and slows ...201627097639
cytotoxic and antibiotic cyclic pentapeptide from an endophytic aspergillus tamarii of ficus carica.a new cyclic pentapeptide, disulfide cyclo-(leu-val-ile-cys-cys) (1), named malformin e, together with 13 known cyclic dipeptides, was isolated from the culture broth of endophytic fungus fr02 from the roots of ficus carica. the strain fr02 was identified as aspergillus tamarii on the basis of morphological characteristics and molecular analyses of internal transcribed spacer (its). their structures were determined by the combination of 1d and 2d nmr spectroscopy, hrms (esi), uv, and marfey's an ...201627147299
designing and characterizing of tramadol hydrochloride transdermal patches prepared with ficus carica fruit mucilage and povidone.the purpose of this investigation was to prepare matrix type transdermal patches of tramadol hcl using various ratios of ficus carica fruit mucilage and povidone. the matrix type transdermal patches were prepared using tramadol hcl with ficus carica fruit mucilage and povidone. the interactions between tramadol hcl with f. carica fruit mucilage and povidone were performed by differential scanning calorimetry (dsc) and fourier transform infrared spectroscopy (ftir). the prepared patches were exam ...201627166538
a new helvolic acid derivative from an endophytic fusarium sp. of ficus carica.a new helvolic acid derivative named helvolic acid methyl ester (1), together with two known helvolic acid compounds, helvolic acid (2) and hydrohelvolic acid (3), were isolated from the fermentation of endophytic fungus fusarium sp. in ficus carica leaves. their structures were elucidated and identified by spectroscopic methods. compounds 1-3 showed potent antifungal and antibacterial activities.201627265219
antioxidant and hepatoprotective properties of dried fig against oxidative stress and hepatotoxicity in rats.the aim of this study was to investigate the hepatoprotective effect and antioxidant role of dried fig (df) (ficus carica l.) against ethanol-induced oxidative stress. experiment was designed as normal control, 20% ethanol, 10% df and 10% df+20% ethanol groups. the hepatoprotective and antioxidant role of the dried df supplementation feed against ethanol induced oxidatif stress were evaluated by liver histopathological changes, measuring liver damage serum enzymes (ldse), antioxidant defense sys ...201627268385
antioxidant, antilipidemic and antidiabetic effects of ficusin with their effects on glut4 translocation and pparγ expression in type 2 diabetic rats.in this study, the antioxidant, antilipidemic and antidiabetic effects of ficusin isolated from ficus carica leaves and their effects on glut4 translocation and pparγ expression were evaluated in hfd-stz induced type 2 diabetic rats. ficusin (20 and 40 mg/kg b. wt.) lowered the levels of fasting blood glucose, plasma insulin and body weight gain, in hfd-stz induced diabetic rats. ficusin also significantly lowered the serum antioxidant enzymes (sod, cat and gpx) and lipids (tc, tg and ffa) level ...201627350165
contributions to the phytotherapies of digestive disorders: traditional knowledge and cultural drivers of manoor valley, northern pakistan.ethno medicinal traditional knowledge regarding the uses of indigenous medicinal plants used for various human digestive disorders are mostly known to the elder community members. as the young generation is not much aware about such vital traditional medicinal practice because they rely on elders.201627353866
panonychus from georgia: survey, taxonomical status and redescription of p. hadzhibejliae (reck, 1947) (acari, tetranychidae).a survey of panonychus species was undertaken across georgia from 2005 to 2014 on various host plants, revealing three species: panonychus citri (mcgregor, 1916), panonychus hadzhibejliae (reck, 1947) and panonychus ulmi (koch, 1836). new hosts for p. ulmi and p. citri are recorded, buxus sempervirens, hedera colchica and prunus laurocerasus for p. ulmi and ficus carica for p. citri, whereas p. hadzhibejliae was only found on f. carica. the newly collected material also allowed us to investigate ...201627395141
propagation of some local fig (ficus carica l.) cultivars by hardwood cuttings under the field conditions in tunisia.this research was carried out in southeast of tunisia in 2009 and 2010, in order to study the propagation of six (ficus carica l.) cultivars by using hardwood cuttings under the field conditions. the effect of the cultivars and the type of buds, shoots age, shoots length, and shoots diameter were recorded. ten cuttings per cultivar and/or cutting types with three replications were planted in rooting unit. percentage of root emergence and six morphological parameters of young fig plants were meas ...201427437458
randomized, double-blind, placebo-controlled trial of ficus carica paste for the management of functional constipation.constipation affects up to 20% of the world's population. the aim of this study was to investigate whether supplementation with ficus carica paste could be used to treat constipation in korean subjects with functional constipation.201627440682
two newly introduced tropical bark and ambrosia beetles (coleoptera: curculionidae, scolytinae) damaging figs (ficus carica) in southern italy.in summer 2014, the bark beetle hypocryphalus scabricollis (eichhoff) and the ambrosia beetle xyleborus bispinatus eichhoff, species new to italy and europe, respectively, were found for the first time in south-eastern sicily (italy). large infestations of the two species were recorded in many plantations of common fig (ficus carica l.) both in 2014 and 2015. data concerning insect characteristics, taxonomy, and distribution are briefly reported.201627470760
an alternative inhibition method for determining cross-reactive allergens.inhibition assays are an useful tool to identify the allergen of primary sensitization of cross-reactive allergens. classical elisa-based inhibition assays are limited by both the availability of commercial standardized allergen extracts and the experience and knowledge needed for making home-made extracts. moreover the direct comparison of the inhibition elisas outcomes between different laboratories is difficult because of different sources of used allergen extracts and a number of methodologi ...201727474838
in vitro activity of plant extracts against biofilm-producing food-related bacteria.the identification of effective antimicrobial agents also active on biofilms is a topic of crucial importance in food and industrial environment. for that purpose methanol extracts of turkish plants, ficus carica l., juglans regia l., olea europaea l., punica granatum l. and rhus coriaria l., were investigated. among the extracts, p. granatum l. and r. coriaria l. showed the best antibacterial activity with minimum inhibitory concentrations (mic) of 78-625μg/ml for listeria monocytogenes and sta ...201627591384
impact of pesticide resistance on toxicity and tolerance of hostplant phytochemicals in amyelois transitella (lepidoptera: pyralidae).for some polyphagous insects, adaptation to phytochemically novel plants can enhance resistance to certain pesticides, but whether pesticide resistance expands tolerance to phytochemicals has not been examined. amyelois transitella walker (navel orangeworm) is an important polyphagous pest of nut and fruit tree crops in california. bifenthrin resistance, partially attributable to enhanced cytochrome p450 (p450)-mediated detoxification, has been reported in an almond-infesting population exposed ...201627620560
in vitro enzymatic investigation of ficus carica (fruit).the present study demonstrates the biological study of ficus carica fruit. methanolic extract of plant fruit was prepared and evaporated under reduced pressure by rota vapor and n- hexane, chloroform, ethyl acetate and n-butanol soluble fractions were prepared separately from crude methanolic extract. these fractions were then screened for acetyl cholinesterase, butryl cholinesterase and lipoxygenase activities. n-butanol soluble fraction showed significant antiacetylcholinesterase activity (78. ...201627731810
plant polysaccharides used as immunostimulants enhance innate immune response and disease resistance against aeromonas hydrophila infection in fish.plant polysaccharides (pps) are an important medicinal plant product, and play a major role in preventing and controlling infectious microbes in aquaculture. the present study investigated the effect of three pps; ficus carica polysaccharides (fcps), radix isatidis polysaccharides (rips), and schisandra chinensis polysaccharides (scps), used as feed additives, on innate immune responses and disease resistance against aeromonas hydrophila in crucian carp. results show that crucian carp fed with t ...201627794459
inhibition of murine norovirus and feline calicivirus by edible herbal extracts.human noroviruses (hunovs) cause foodborne and waterborne viral gastroenteritis worldwide. because hunov culture systems have not been developed thus far, no available medicines or vaccines preventing infection with hunovs exist. some herbal extracts were considered as phytomedicines because of their bioactive components. in this study, the inhibitory effects of 29 edible herbal extracts against the norovirus surrogates murine norovirus (mnv) and feline calicivirus (fcv) were examined. fcv was s ...201727807684
pharmacological evaluation for improvement of kanazawa sutra, medicinal thread for anal fistula.kanazawa sutra (kans) is a medicinal thread that is used for the treatment of anal fistula. it is used as a substitute for kshara sutra (ks) which is used in ayurvedic medicine. kans is composed of ficus carica latex (fcl), capsicum annuum tincture (cat), achyranthes fauriei kshara (which is processed ash from the whole plant) and powdered curcuma longa rhizome (clr). in this study, we evaluated the ingredients of kans by measuring nitric oxide (no) production in murine macrophage-like cell line ...201727900596
tissue-specific transcriptome and hormonal regulation of pollinated and parthenocarpic fig (ficus carica l.) fruit suggest that fruit ripening is coordinated by the reproductive part of the syconium.in the unconventional climacteric fig (ficus carica) fruit, pollinated and parthenocarpic fruit of the same genotype exhibit different ripening characteristics. integrative comparative analyses of tissue-specific transcript and of hormone levels during fruit repining from pollinated vs. parthenocarpic fig fruit were employed to unravel the similarities and differences in their regulatory processes during fruit repining. assembling tissue-specific transcripts into 147,000 transcripts with 53,000 ...201627965676
differential accumulation of photosynthetic proteins regulates diurnal photochemical adjustments of psii in common fig (ficus carica l.) leaves.molecular processes involved in photosystem ii adaptation of woody species to diurnal changes in light and temperature conditions are still not well understood. regarding this, here we investigated differences between young and mature leaves of common fig (ficus carica l.) in photosynthetic performance as well as accumulation of the main photosynthetic proteins: light harvesting complex ii, d1 protein and rubisco large subunit. investigated leaf types revealed different adjustment mechanisms to ...201727987432
characterization of microbial population of breba and main crops (ficus carica) during cold storage: influence of passive modified atmospheres (map) and antimicrobial extract application.the purpose of this work was to study the changes of bacterial and fungal population of breba fruits such as 'banane' and 'san antonio' as well as 'cuello dama negro', 'cuello dama blanco' and 'san antonio' fig cultivars stored in passive modified atmospheres (map) by the use of three different microperforated films (m10 with 16 holes; m30 with five holes and m50 with three holes). moreover the effects of the application of aqueous soy polyphenolic antimicrobial extract (ape), alone or combined ...201728040180
analysis of genetic diversity of tunisian caprifig (ficus carica l.) accessions using simple sequence repeat (ssr) markers.the common fig (ficus carica l.) is a gynodioecious species with two sexual forms: male trees (caprifigs) with male and female flowers and female trees that produce only female flowers that will result in the edible fig syconium. in this study the genetic diversity of 20 tunisian accessions of caprifig is analyzed using ssr markers previously developed for this crop.201528096760
identification of ran1 orthologue associated with sex determination through whole genome sequencing analysis in fig (ficus carica l.).with the aim of identifying sex determinants of fig, we generated the first draft genome sequence of fig and conducted the subsequent analyses. linkage analysis with a high-density genetic map established by a restriction-site associated sequencing technique, and genome-wide association study followed by whole-genome resequencing analysis identified two missense mutations in responsive-to-antagonist1 (ran1) orthologue encoding copper-transporting atpase completely associated with sex phenotypes ...201728120935
evaluation of antihypertensive potential of ficus carica fruit.ficus carica l. (moraceae) fruit is said to possess cardiovascular activity and has been used empirically in traditional phytotherapies for the treatment of hypertension and various other cardiovascular diseases.201728187689
protective effects of ficus carica leaves on glucose and lipids levels, carbohydrate metabolism enzymes and β-cells in type 2 diabetic rats.the decoctions of ficus carica linn. (moraceae) leaves are used in the folklore treatment of diabetes.201728193094
hplc-dad-qtof-ms profiling of phenolics from leaf extracts of two tunisian fig cultivars: potential as a functional food.the phenolic constituents of the aqueous-ethanolic extract of two tunisian ficus carica leaves cultivars and their hypoglycaemic, hypolipidaemic and antioxidative activities in alloxan-induced diabetic rats were investigated. our results demonstrated that the treatment with the leaves extracts of f. carica improved lipid profile and reduced blood glucose level as well as thiobarbituric acid-reactive substances content. the antioxidant enzymes activity in the liver and heart tissues of diabetic r ...201728226292
does regular use of a complementary medicine of olea europe and ficus carica have adverse effects on lipid profile and fasting blood glucose of rheumatoid arthritis (ra) patients under treatment with dmard regimens containing methotrexate?rheumatoid arthritis (ra) patients are vulnerable to cardiovascular morbidity and mortality in which atherosclerosis plays a major role. in this study, the lipid profile and fasting blood sugar (fbs) of ra patients receiving a complementary medicine of olive and fig, as add-on therapy for routine disease-modifying antirheumatic drugs (dmards) regimen containing low dose methotrexate (mtx), were studied. a randomized controlled clinical trial was designed. adult ra patients were randomly allocate ...201628243292
non-crop plants used as hosts by drosophila suzukii in europe.the invasive spotted wing drosophila drosophila suzukii, a fruit fly of asian origin, is a major pest of a wide variety of berry and stone fruits in europe. one of the characteristics of this fly is its wide host range. a better knowledge of its host range outside cultivated areas is essential to develop sustainable integrated pest management strategies. field surveys were carried out during two years in italy, the netherlands and switzerland. fruits of 165 potential host plant species were coll ...201628275324
harvesting, rumination, digestion, and passage of fruit and leaf diets by a small ruminant, the blue duiker.because small ruminants (<15 kg) have a high ratio of metabolic rate to fermentation capacity, they are expected to select and require low-fiber, nutrient-dense concentrate diets. however, recent studies suggest that small ruminants may not be as limited in their digestive capacity as previously thought. in this study, we examined harvesting, rumination, digestion, and passage of three diets (domestic figs ficus carica, fresh alfalfa medicago sativa, and pacific willow leaves salix lasiandra) ra ...200028308754
diurnal changes in chlorophylla fluorescence and carotenoid composition inopuntia ficus-indica, a cam plant, and in three c3 species in portugal during summer.diurnal changes in chlorophylla fluorescence were determined in four species, differing in life form, in portugal during the summer of 1989. these includedopuntia ficus-indica, a cam plant, andhelianthus annuus, ficus carica andarbutus unedo, three c3 species. steady state fluorescence yield,f s, and maximum fluorescence yield,f m', were determined at different times of the day. using the model of genty et al. (1989), the photon use efficiency of photosystem ii electron transport,φ e, was calcul ...199228313502
mitochondria as a target for the cardioprotective effects of cydonia oblonga mill. and ficus carica l. in doxorubicin-induced cardiotoxicity.quince (cydonia oblonga mill.) and fig (ficus carica l.) exhibit a broad spectrum of pharmacological activities. regarding the cardiotoxic effect of doxorubicin (dox) is mediated mainly through mitochondrial oxidative stress and dysfunction; the present study evaluated the cardioprotective effects of the aqueous extracts of cydonia oblonga mill. fruit (aco) and ficus carica l. fruit (afc) against dox-induced cardiotoxicity. cardiomyocytes toxicity was induced in male sprague dawley rats by intra ...201728320040
biosynthesis of silver nanoparticles using dried fruit extract of ficus carica - screening for its anticancer activity and toxicity in animal models.there is an increasing commercial demand for various nanoparticles due to their extensive applicability in various areas such as electronics, catalysis, chemistry, energy and medicine. metallic nanoparticles are traditionally synthesized by wet chemical techniques, where the chemicals used are quite often toxic and flammable. fig has been a typical fruit component of the health-promoting mediterranean diet for a very long time. in the present study, we describe a cost effective and eco-friendly ...201728377268
effect of ficus carica leaf extract on the gene expression of selected factors in hacat cells.ficus carica linn. (fc), common fig, has been traditionally used for many metabolic, cardiovasculary, respiratory, gastrointestinal, and skin disorders. several studies were performed showing its anti-inflammatory, anti-angiogenic, anticancerogenic, and tissue-protective effects. in all of those studies, the positive effects of fc were concluded as the result of its antioxidant and anti-inflammatory features due to the polyphenols it contains.201728432719
studies on the metabolites difference of psoralen/isopsoralen in human and six mammalian liver microsomes in vitro by uhplc-ms/ms.psoralen and isopsoralen are found in many fruits, vegetables and traditional chinese medicines (tcm), such as ficus carica l., celery, fructus psoraleae etc. modern pharmacological studies found that psoralen and isopsoralen can show estrogen-like activity, antitumor, and antibacterial activities etc. however, some research results also show some liver damage associated with the use of psoralen/isopsoralen or related medicines in human. many studies focus on the pharmacological activities of ps ...201728448889
volatile profile of greek dried white figs (ficus carica l.) and investigation of the role of β-damascenone in aroma formation in fig liquors.during an investigation of the chemical profile of greek figs (ficus carica l.), several aqueous ethanol extracts (liquors) were prepared from dried smyrna fig varieties cultivated in the two major fig-producing geographical areas in greece: peloponnese and evia island. the distinctive aroma observed among the prepared fig liquors led to the investigation of the odor profile of the different fig cultivars through hs-spme coupled with gc/ms analysis, with focus on the factors that affect it befor ...201728474390
corrigendum: identification of ran1 orthologue associated with sex determination through whole genome sequencing analysis in fig (ficus carica l.). 201728488674
inhibitory activity of different medicinal extracts from thuja leaves, ginger roots, harmal seeds and turmeric rhizomes against fig leaf mottle-associated virus 1 (flmav-1) infecting figs in mecca region.fig leaf mottle-associated virus-1 (flmav-1) is a closterovirus newly identified in fig trees, in the mecca region, suffering from mosaic disease symptoms and apparently is compromising the fig plantation in the country. in the present study, we demonstrated the efficiency of two in vivo experiments including pre and post treatments using thuja leaf, ginger roots, harmal seeds and turmeric rhizome extracts on symptoms expression of rooted cuttings infected with flmav-1- and their impact on virus ...201728490968
sex differences and flowering phenology in the common fig, ficus carica l. 197928563939
the stability of the symbiosis between dioecious figs and their pollinators: a study of ficus carica l. and blastophaga psenes l.each ficus species depends on a specific mutualistic wasp for pollination. the wasp breeds on the fig, each larva destroying a female flower. it is, however, not known why the wasps have not evolved the ability to use all female flowers. in "dioecious" figs, the wasp can only breed in the female flowers of the "male" trees, so that pollination of a female tree is always lethal. the wasps should therefore be selected to avoid female trees. field data is presented showing that the fruiting phenolo ...198728564365
phenylpropanoid composition in fig (ficus carica l.) leaves.the leaves of fig (ficus carica l.) have been used for traditional and chinese medicine. we determined the composition of phenylpropanoids (polyphenols and furanocoumarins) as a functional agent in the leaves of 37 cultivars of fig. the most abundant polyphenol was caffeoylmalic acid (12.0-26.6 mg/g dry weight), followed by rutin (4.7-14.6 mg/g dry weight) and isoschaftoside (2.5-6.4 mg/g dry weight). psoralen (3.8-23.0 mg/g dry weight) was dominant in the furanocoumarins. in molar amounts, psor ...201728589249
efficacy of tissue culture in virus elimination from caprifig and female fig varieties (ficus carica l.).fig mosaic disease (fmd) is a viral disease that spreads in all tunisian fig (ficus carica l.) orchards. rt-pcr technique was applied to leaf samples of 29 fig accessions of 15 fig varieties from the fig germplasm collection of high agronomic institute (i.s.a) of chatt-mariem, to detect viruses associated to fmd. analysis results show that 65.5% of the accessions (19/29) and 80.0% (12/15) of the fig varieties are infected by fmd-associated viruses. from all fig accessions, 41.4% of them are with ...201728592947
first report of the fig cyst nematode, heterodera fici kirjanova, on fig tree, ficus carica, in ontario, canada.although fig trees are a popular ornamental fruit tree in subtropical regions, some hardy species, such as ficus carica, have been grown in the west coast of british columbia and southern ontario in canada. the fig cyst nematode, heterodera fici kirjanova, is a pest on fig plants, and the heavy infestation can cause retarded growth and yellowing of leaves (maqbool et al., 1987). in the spring of 2016, a sample of rhizosphere from a potted fig (f. carica) seedling was submitted to the nematology ...201728706311
enhanced and green extraction polyphenols and furanocoumarins from fig (ficus carica l.) leaves using deep eutectic solvents.nowadays, green extraction of bioactive compounds from medicinal plants has gained increasing attention. as green solvent, deep eutectic solvent (des) have been highly rated to replace toxic organic solvents in extraction process. in present study, to simultaneous extraction five main bioactive compounds from fig leaves, des was tailor-made. the tailor-made des composed of a 3:3:3 molar ratio of glycerol, xylitol and d-(-)-fructose showed enhanced extraction yields for five target compounds simu ...201728710995
cultivar-specific transcriptome prediction and annotation in ficus carica l.the availability of transcriptomic data sequence is a key step for functional genomics studies. recently, a repertoire of predicted genes of a japanese cultivar of fig (ficus carica l.) was released. because of the great phenotypic variability that can be found in this species, we decided to study another fig genotype, the italian cv. dottato, in order to perform comparative studies between the two cultivars and extend the pan genome of this species. we isolated, sequenced and assembled fig geno ...201728736702
colorimetric sensing of toxic metal and antibacterial studies by using bioextract synthesized silver nanoparticles.here, we report the simple and cost effective colorimetric technique for the determination of toxic metals (hg(2+)) in aqueous sample by using bioextract silver nanoparticles (agnps). the indigenous agnps were synthesised by green and ecologically friendly style using extract of fig (ficus carica) leaf. the synthesized agnps were confirmed by uv-vis spectroscopy, ft-ir spectroscopy, and scanning electron microscopy methods. the synthesis of agnps was observed by its colour changing from light ye ...201728748516
application of nanocompostie chitosan and carboxymethyl cellulose films containing natural preservative compounds in minced camel's meat.in the present study, novel films based on nanomontmorillonite-chitosan (mmt-ch) and nanomontmorillonite-carboxymethyl cellulose (mmt-cmc) incorporated with different concentrations of ziziphora clinopodioides essential oil (zeo; 0.5, 1 and 2%) alone and in combination with ficus carica extract (fch; 1%) were investigated as active packaging materials for minced camel's meat to increase the shelf life (microbial, chemical and sensory properties) and inhibit the growth of listeria monocytogenes a ...201728847602
synergistic hepatoprotective and antioxidant effect of artichoke, fig, blackberry herbal mixture on hepg2 cells and their metabolic profiling using nmr coupled with chemometrics.the edible plants have long been reported to possess a lot of biological activities. herein, the hepatoprotective and the antioxidant activities of the aqueous infusion of the edible parts of cynara cardunculus, ficus carica, and morus nigra and their herbal mixture (cfm) was investigated in vitro using ccl4 induced damage in hepg2 cells. the highest amelioration was observed via the consumption of cfm at 1 mg/ml showing 47.00% and 37.09% decline in aspartate transaminase and alanine transaminas ...201728898531
food strategies of renal atrophy based on avicenna and conventional medicine.kidneys have an important role in the body. any damage to kidney role can damage many organs of the body. traditional persian medicine (tpm) or iranian traditional medicine (itm) is an ancient temperamental medicine with many literatures about kidney diseases and avicenna (980-1025 ad) describes kidney diseases in details. this is a review study by searching of the most important clinical and pharmaceutical tpm textbooks such as the canon of medicine by avicenna and scientific data banks using k ...201729034182
a new topical treatment of atopic dermatitis in pediatric patients based on ficus carica l. (fig): a randomized, placebo-controlled clinical trial.atopic dermatitis (ad) is a common, chronic, relapsing and inflammatory skin disease characterized by pruritus and xerosis (dry skin). its prevalence is on the increase worldwide, particularly in children. as the pathogenesis of ad involves a complex interaction of genetic, environmental and immunological factors, its definitive treatment is difficult.201729154073
review of natural product-derived compounds as potent antiglioblastoma drugs.common care for glioblastoma multiforme (gbm) is a surgical resection followed by radiotherapy and temozolomide- (tmz-) based chemotherapy. unfortunately, these therapies remain inadequate involving severe mortality and recurrence. recently, new approaches discovering combinations of multiple inhibitors have been proposed along with the identification of key driver mutations that are specific to each patient. to date, this approach is still limited by the lack of effective therapy. hopefully, no ...201729181405
regulation of fig (ficus carica l.) fruit color: metabolomic and transcriptomic analyses of the flavonoid biosynthetic pathway.combined metabolomic and transcriptomic analyses were carried out with fig cultivar green peel and its color mutant "purple peel." five and twenty-two metabolites were identified as having significantly different contents between fruit peels of the two cultivars at young and mature stages, respectively. cyanidin o-malonylhexoside demonstrated a 3,992-fold increase in the mature purple peel, the first identification of a major cyanidin in fig fruit; cyanidin 3-o-glucoside, cyanidin o-malonylhexos ...201729209349
cloning and aggregation characterization of rubber elongation factor and small rubber particle protein from ficus carica.rubber elongation factor (ref) and small rubber particle protein (srpp) are major latex proteins harvested from hevea brasiliensis (the rubber tree; hbref and hbsrpp, respectively). their amino acid sequences exhibit high homology with each other. in the present study, we cloned two cdnas encoding ref/srpp-family proteins (fcref/srpp-1 and -2) from the laticifers of ficus carica (fig tree). the amino acid sequences of these proteins showed high homology not only with each other but also with hbr ...201729214498
impact of metal ionic characteristics on adsorption potential of ficus carica leaves using qspr modeling.the present study describes quantitative structure property relationship (qspr) modeling to relate metal ions characteristics with adsorption potential of ficus carica leaves for 13 selected metal ions (ca+2, cr+3, co+2, cu+2, cd+2, k+1, mg+2, mn+2, na+1, ni+2, pb+2, zn+2, and fe+2) to generate qspr model. a set of 21 characteristic descriptors were selected and relationship of these metal characteristics with adsorptive behavior of metal ions was investigated. stepwise multiple linear regressio ...201729281503
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