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ciprofloxacin treatment of chlamydial infections of urogenital tracts of women.ciprofloxacin was evaluated in chlamydial infections of the urogenital tracts of women treated with a dosage regimen of 500 mg orally twice a day for seven days. of the 40 women evaluated, 30 were infected with chlamydia trachomatis only, two were infected with neisseria gonorrhoeae only, and a further eight had combined gonococcal and chlamydial infections. ten were found to be harbouring chlamydia trachomatis in the urethra as well as the cervix. neisseria gonorrhoeae was eradicated from all p ...19883278970
mycoplasma hominis septic arthritis.an unusual case is described of extragenital mycoplasma hominis infection presenting as a septic arthritis of the hip joint in a young paraplegic girl. the few reported cases of m. hominis septic arthritis are summarized. based on the current case and these reported cases, the etiology, presentation, diagnosis, and treatment of this infection are discussed.19883281546
septic arthritis due to dual infection with mycoplasma hominis and ureaplasma urealyticum.acute septic arthritis of a knee and shoulder developed in a 32-year-old renal transplant patient. cultures yielded mycoplasma hominis and at least 1, and possibly 2, strains of ureaplasma urealyticum. doxycycline therapy controlled the symptoms and signs, and the joints became culture negative. on stopping therapy after 7 months, the arthritis recurred and u. urealyticum was again isolated from the shoulder joint. cessation of doxycycline almost 4 years after the initial episode resulted in ano ...19883283360
nongenitourinary infections caused by mycoplasma hominis in adults.eleven new cases of mycoplasma hominis infection occurring outside the genitourinary tract in adults not in the puerperium were evaluated in relation to the 25 cases previously reported. cases of bacteremia (n = 14) were commonly associated with trauma or manipulation of the genitourinary tract and were often self-limited. wound infections (n = 14) followed surgery by 4-14 days in most cases and may have arisen from contamination from the genitourinary or respiratory tract. joint infections (n = ...19883293162
[isolation of mycoplasma and chlamydia in patients with urogenital infections].vaginal/cervical swabs, catheter urine and/or puncture of the bladder (p.b.) from 880 females with urogenital diseases were examined microbiologically. mycoplasmas (ureaplasma urealyticum, mycoplasma hominis) could be isolated from 321 females (36.5%), and chlamydia trachomatis from 42 (4.8%). mycoplasmas and c. trachomatis were more frequent in the age between 21 and 30 years (53 and 11.8% respectively). in 32.8% of the entire collective mycoplasmas could be detected in vaginal swabs. in contra ...19873301631
mycoplasma hominis in patients with pelvic inflammatory disease.the role of mycoplasma hominis in pelvic inflammatory disease (pid) was studied among 35 patients with laparoscopically confirmed salpingitis or histopathologically confirmed plasma cell endometritis. m. hominis was isolated from the cervix of 15 patients, from the rectum of 13 patients, and from the endometrium of 5 patients. only two of these five patients had m. hominis isolated from the endometrium in the absence of chlamydia trachomatis or neisseria gonorrheae, the major pid-causing organis ...19873312109
electrophoretic analysis of proteins from mycoplasma hominis strains detected by sds-page, two-dimensional gel electrophoresis and immunoblotting.the proteins of 14 strains of mycoplasma hominis were compared by sds-page in gradient gels, by two-dimensional (2d) gel electrophoresis of extracts of 35s-labelled cells and by immunoblot analysis of cell proteins. the strains examined included the m. hominis type strain pg21 and 13 others isolated variously from genital tract, mouth, blood, upper urinary tract and a wound. these 14 strains shared 76-99% of proteins in sds-gradient gel analysis and 41-72% in the 2d gels. as expected, the immuno ...19873309143
attachment of mycoplasma hominis to human cell cultures.clinical isolates, cell-culture contaminants, and the type strain pg21 of mycoplasma hominis were examined for attachment to erythrocytes and human cell cultures. strain 13428 (from blood, postpartum fever) and strain 1184 (cell culture) attached to human and guinea pig erythrocytes, but there were no differences in attachment activities between these strains. however, five m. hominis strains isolated from different tissue sites showed quantitative differences in attachment to human widr (intest ...19873312097
dna probes for the detection of mycoplasmas in genital specimens.the utility of whole-genomic dna probes for the detection of infections by genital mycoplasmas was investigated in 220 men attending a sexually transmitted diseases clinic. in 144 patients, probe results were compared with quantitative culture results. the prevalence of mycoplasma hominis was 11% by culture, whereas the prevalence of ureaplasmas was 38%. the m. hominis dna probe detected 9 of 16 m. hominis culture-positive specimens and 2 of 128 culture-negative specimens. the ureaplasma urealyt ...19873312098
[detection and identification of mycoplasma infections by dna hybridization].infection of cell cultures by mycoplasmas can be detected by hybridization of the dna of suspected cell cultures with recombinant plasmids containing fragments of the mycoplasma dna. the test is very sensitive and allows detection of as little as 1 ng of mycoplasmal dna, roughly equivalent to the dna amount of 10(6) mycoplasmas. this approach turns out to be effective for detection and identification of mycoplasmas in clinical material, plant and insect tissues. a set of dna probes for detection ...19873318046
[genital mycoplasma infections--clinical aspects, diagnosis and therapy].ureaplasma urealyticum und mycoplasma hominis are frequently isolated from the urogenital tract of sexually active persons. their pathogenetic role in urogenital infections and infertility are still controversial. u. urealyticum can cause urethritis and most likely also chronic prostatitis. m. hominis can cause cystitis, salpingitis, and postpartal fever in women and meningitis in newborns. m. genitalium was recently isolated from patients with urethritis and salpingitis. the diagnosis is made b ...19873318082
roxithromycin in nongonococcal urethritis.this presentation is a summary of five different studies on the efficacy and tolerance of roxithromycin in the treatment of non-gonococcal genital infections. three of the studies were double-blind comparative and two were open studies. of the 924 out-patients whose data were analysed for clinical efficacy, 637 received treatment with roxithromycin 150 mg bd. the standard dose of roxithromycin, 150 mg bd for ten days, was compared with doxycycline 200 mg daily, lymecycline 300 mg bd and roxithro ...19873323168
a review of the in-vitro activity of roxithromycin against genital pathogens.the in-vitro activity of roxithromycin against neisseria gonorrhoeae, chlamydia trachomatis, mycoplasma hominis, ureaplasma urealyticum, treponema pallidum, gardnerella vaginalis and haemophilus ducreyi is reviewed. roxithromycin demonstrated equivalent activity to erythromycin against n. gonorrhoeae, c. trachomatis, m. hominis, u. urealyticum, g. vaginalis and h. ducreyi. in a rabbit model for syphilis, potentially useful activity against t. pallidum has been demonstrated.19873323169
antimicrobial activity of amniotic fluid against chlamydia trachomatis, mycoplasma hominis, and ureaplasma urealyticum.amniotic fluids obtained by amniocentesis at 16 weeks to term were examined for the presence of chlamydia trachomatis, mycoplasma hominis, and ureaplasma urealyticum. of 140 fluids tested, none harbored chlamydiae, and only one harbored mycoplasma, m. hominis. a number of amniotic fluids were subsequently tested for their ability to inhibit the growth of these microorganisms. amniotic fluids and chlamydial suspensions in a 2:1 ratio were incubated 30 to 90 minutes before their inoculation in mcc ...19883337164
extragenital mycoplasma hominis infection: a report of two cases.mycoplasma hominis was isolated from the surgical wounds of two patients. one of these patients developed a septicaemia-like illness after coronary artery vein-graft surgery. mycopl. hominis was isolated from the sternotomy wound and pleural fluid of this patient but not from his blood. no other pathogens were isolated. the second patient developed a low-grade soft-tissue infection due to mycopl. hominis in a craniotomy wound; his condition responded to tetracycline treatment. the source of infe ...19883340029
mycoplasma hominis surgical wound infection: a case report and discussion.a patient with mycoplasma hominis infection of a clean surgical wound that contained a prosthetic vascular graft had clinical findings similar to those observed in patients with acute bacterial infections. etiologic diagnosis was delayed because m. hominis is not appreciated as a cause of surgical wound infections and because of its special growth characteristics. confirmation of m. hominis infection requires awareness on the part of the clinician and assistance from an informed microbiologist. ...19883340994
mycoplasma hominis septicemia after heart surgery. 19883364454
association of coexisting vaginal infections and multiple abusers in female children with genital warts.all 11 girls less than 12 years of age presenting to the pediatric clinic between 1980 and 1986 with genital warts were evaluated by the child protection team for possible sexual abuse. nine of the 11 girls had condylomata acuminata, and two had verruca vulgaris. ten of the 11 had historical and/or physical evidence other than the warts that confirmed sexual abuse. six girls had coexisting vaginal infections such as bacterial vaginosis and infections due to various pathogens including neisseria ...19883358240
evidence that chlamydia trachomatis causes seronegative arthritis in women.chlamydia trachomatis elementary bodies (ebs) were found in synovial membranes or synovial fluid cell deposits from five of 15 women with seronegative mono- or oligoarthritis by means of a fluorescein conjugated anti-chlamydial monoclonal antibody (micro trak; syva). genital tract specimens were taken from only five of the patients, one of whom had intra-articular ebs, but none was chlamydia positive. six of 10 patients tested were hla-b27 positive, and chlamydial igg antibody, measured by micro ...19883365028
isolation of genital mycoplasmas and chlamydia trachomatis in stillborn and neonatal autopsy material.chlamydia trachomatis and the genital mycoplasmas are significantly prevalent in sexually active women. how these organisms may affect the outcome of pregnancy and the neonate was the principal thrust of this investigation. placenta, liver, and lung tissue were cultured from mycoplasma hominis, ureaplasma urealyticum, chlamydia trachomatis, and aerobic as well as anaerobic bacteria in 432 stillborn and neonatal autopsies. genital mycoplasmas were isolated from 36 cases (8.3%). acute chorioamnion ...19883382330
distinction of species and strains of mycoplasmas (mollicutes) by genomic dna fingerprints with an rrna gene probe.genomic fingerprints of acholeplasma laidlawii, mycoplasma hominis, and mycoplasma pneumoniae strains were obtained by southern blot hybridization of the digested mycoplasmal dnas with an rrna gene probe. the hybridization patterns revealed genotypic heterogeneity among a. laidlawii and m. hominis strains and a remarkable degree of homogeneity among m. pneumoniae strains isolated from pneumonia patients during a 10-year period. genomic fingerprints with the rrna gene probe can thus serve as indi ...19883384931
hematoma infected with mycoplasma hominis.although mycoplasmas are commonly isolated in the genitourinary and upper respiratory tracts, they are rarely isolated from other sites. we describe a case of a young woman with trauma to her pelvis and genitourinary tract who had a thigh hematoma infected with mycoplasma hominis. the patient had persistent systemic symptoms that resolved with appropriate antibiotics and surgical drainage. this case as well as other cases of mycoplasma-infected hematomas point out the need to consider mycoplasma ...19883399998
[mycoplasma infections of the kidneys].from the urine cultures of 1238 patients with renal or suspicious for renal disease mycoplasmas were isolated in 119 (9.6%). in 75 patients the mycoplasmas were typified. in 56 patients m. hominis and in 24 patients ur. urealyticum were isolated. in 52 patients there were data for pyelonephritis, in 46 patients there was no renal infection. in 21 patents there were mycoplasmas and arterial hypertension without sufficient data for pyelonephritis. in the group of patients with pyelonephritis and a ...19883414078
urinary tract symptoms: microbiologic evaluation in rural family practice.in order to define the etiology of urinary symptoms in rural family practice, this study examines 106 patients (88 women, 18 men) who went to their family physicians in private practice or a resident-faculty practice with genitourinary symptoms. evaluation of each patient included history, physical examination, urinalysis, and urine or cervical cultures for bacteria, mycoplasma, and chlamydia. using agar plate culturing techniques, 37 patients (35 percent) were identified as having significant u ...19883414387
[new diagnostic and therapeutic directions in so-called essential anorectal pain].the authors report a study of 40 patients affected with "essential" ano-rectal neuralgia. it manifests itself by frequent urinary disorders discovered most of the time at the interview of the patient and emphasizes in many cases the presence of psychosomatic disorders. this study has also demonstrated frequent abnormalities of laboratory tests including: chlamydiae serology, urethral samplings and cyto-bacteriological examination of urine looking for: chlamydiae, ureaplasma urealyticum, mycoplas ...19873426144
[biological properties of ureaplasma urealyticum and mycoplasma hominis isolated from patients with urethral inflammations. iii. occurrence of serological types of u. urealyticum among the strains isolated from healthy men those with urethral inflammations, and their sexual partners]. 19873437785
a dna probe for detecting mycoplasma genitalium in clinical specimens.despite decades of careful study, the etiologies of all cases of pelvic inflammatory disease (pid) and non-gonococcal urethritis (ngu) have yet to be described. mycoplasma genitalium is a newly described organism which has been implicated as a cause of both pid and ngu. because of fastidious growth requirements, prolonged incubation time and frequent overgrowth in clinical specimens by mycoplasma hominis, non-culture methods need to be developed for its detection. we have cloned m. genitalium dn ...19873453423
[biological properties of ureaplasma urealyticum and mycoplasma hominis isolated from patients with urethral inflammations. iv. occurrence of serological variants of m. hominis among the strains isolated from healthy men those with urethral inflammations and their sexual partners]. 19873437786
isolation of genital mycoplasmas from the blood of neonates and women with pelvic infection using conventional sps-free blood culture media.standard blood culture media used in our laboratory were tested for their ability to support the growth of mycoplasma hominis and ureaplasma urealyticum. small inocula (approximately 10 colony forming units per ml) of both organisms grew in diphasic tryptone soya medium but not in any of several media containing sodium polyanetholesulphonate (sps) including a modified schaedler broth (rwh anaerobic medium) and two bactec media (6b and 7d). both organisms were inhibited even by very low concentra ...19873431914
urinary tract infection (uti) in a couple caused by mycoplasma hominis and ureaplasma urealyticum (a case report). 19873449457
effect of short term treatment of non-gonococcal urethritis with minocycline.two hundred and forty four men with non-gonococcal urethritis (ngu) took part in a trial of minocycline. chlamydiae were isolated from 34%, ureaplasmas from 47.1%, and mycoplasma hominis from 10.2%. these micro-organisms were isolated least often from men suffering their third or more attack of ngu, and men in this group failed most often to respond to minocycline. irrespective of the micro-organisms isolated originally or the number of previous attacks, the failure rate (10%) for men receiving ...19863512418
further studies on genital mycoplasmas in intra-amniotic infection: blood cultures and serologic response.mycoplasma hominis is recovered significantly more often in amniotic fluid of women with intra-amniotic infection than in matched control women, but ureaplasma urealyticum is found in 50% of amniotic fluid samples of both groups. to gain further understanding, we performed blood cultures for genital mycoplasmas and measured serologic responses by a micro enzyme-linked immunosorbent assay method in women with intra-amniotic infection and in control subjects. in blood cultures of 81 women with int ...19863515945
aetiology of urinary symptoms in sexually active women.two hundred and fifty six unselected women, 50 of whom had urinary symptoms (frequency of urination or dysuria, or both), and who were attending a department of genitourinary medicine, were investigated. the urinary symptoms were associated both with pyuria and the isolation of undoubted pathogens from midstream urine (msu) specimens. no associations were found between urinary symptoms and the isolation of neisseria gonorrhoeae or chlamydia trachomatis from the urethra or cervix; the recovery of ...19863533756
[amine colpitis].significance of koh test and isonitril (isocyanide) reaction tested in 104 patients was compared with our microbial culture results. in gardnerella vaginalis as well as in no spores forming anaerobic germs the koh test was not and the isonitril reaction was only insignificant reliable. both tests are not able to substitute the procedures of culturing germs including those of mycoplasma hominis and ureaplasma urealyticum.19863532626
[chlamydia trachomatis in patients with genital contact infections in austria--studies of 3,367 patients].in order to evaluate the epidemiological importance of chlamydia trachomatis (c. trachomatis) as a genital microorganism, data were obtained from 3,367 patients with sexually transmitted diseases in vienna and analyzed by computer-assisted methods. c. trachomatis was cultured in 26.1% of 2,594 patients investigated for the first time. the microorganism was found more often in male patients (31.3%) than in female patients (21%). 32.2% of positive chlamydia cultures were obtained from patients wit ...19863538672
ureaplasma urealyticum as a cause of postpartum fever.mycoplasma hominis has been shown to cause a postpartum fever in nonimmune women and among the approximately 5% of febrile postpartum women who have the organism isolated from the blood. ureaplasma urealyticum causes postpartum fever in the 20% of febrile women with u. urealyticum alone isolated from the endometrium. about 5% of febrile postpartum women have u. urealyticum isolated from the blood. these data suggest that both genital mycoplasmas can cause postpartum fever.19863540898
sternotomy infections with mycoplasma hominis.mycoplasma hominis caused sternal wound infections with mediastinitis in three patients. one infection occurred in a nonimmunocompromised man after coronary artery bypass grafting. the wound did not heal after repeated debridement, closed irrigation of the mediastinum with povidone-iodine solution, and antimycoplasmal chemotherapy; muscle flap grafting was eventually required. two infections occurred in recipients of heart-lung transplants after the isolation of mycoplasma from bronchial secreti ...19873541722
[in vitro activity of nitroxoline on urogenital mycoplasmas].the product nitroxoline was studied in vitro for its activity towards ureaplasma urealyticum and mycoplasma hominis. in view of the low mic values obtained, it seems nitroxoline could be used in the treatment of urinary infections. it is bactericidal, and should not produce resistant strains.19863543811
effect on birth weight of erythromycin treatment of pregnant women.to test the hypothesis that treatment with antibiotics prevents low birth weight, pregnant women whose vaginal cultures contained ureaplasma urealyticum or mycoplasma hominis (or both) and who gave written informed consent were treated with one of the following: identical looking capsules containing 250 mg of either erythromycin estolate or stearate (active against u urealyticum), or 150 mg of clindamycin hydrochloride (active against m hominis), or placebo, four times daily for six weeks in a r ...19873543767
mycoplasmas and in vitro fertilization.semen samples taken from 135 patients attending an in vitro fertilization clinic were shown to be colonized, 53 with ureaplasma urealyticum (39%) and 16 with mycoplasma hominis (12%). an unidentified mycoplasma species was isolated from the sperm of two patients. m. hominis was recovered from all the washed sperm samples taken from colonized semen, whereas washing the sperm eradicated u. urealyticum from 71% of colonized semen. the presence of mycoplasmas in semen made no significant difference ...19873552747
colonization of sexually abused children with genital mycoplasmas.although sexually abused children are usually evaluated only for the presence of infections with neisseria gonorrhoeae and treponema pallidum, they are also at risk for acquiring other sexually transmitted organisms prevalent in the adult population. accordingly, we examined pharyngeal, anorectal and genital specimens from 50 children who had been sexually abused and from 40 healthy children who served as controls; these specimens were cultured for mycoplasma hominis and ureaplasma urealyticum. ...19873563830
infection with multiple sexually transmitted agents.a patient named as a contact by an individual with gonorrhea and syphilis was found to be an asymptomatic carrier of seven organisms known to be transmitted sexually. cultures were positive for neisseria gonorrhoeae, chlamydia trachomatis, gardnerella vaginalis, mycoplasma hominis, ureaplasma urealyticum, and herpes simplex virus. trichomonas vaginalis was detected by a wet preparation and the papanicolaou smear. the cervix was found to have an ulcer on the posterior lip that yielded herpes simp ...19873573062
[incidence of mycoplasma hominis and ureaplasma urealyticum in pregnant women and gynecologic patients and their treatment with doxycycline]. 19873587970
bacteraemia and pelvic infection in women due to ureaplasma urealyticum and mycoplasma hominis.during a 22-month period, pelvic infection with bacteraemia that was due to genital mycoplasmas was diagnosed in 12 adult patients at the royal women's hospital. mycoplasma hominis was isolated from seven patients and ureaplasma urealyticum from five patients. infections occurred postpartum in seven patients (in three patients after a vaginal delivery and in four patients after a caesarean section) and after gynaecological procedures in five patients. all patients were moderately ill. during the ...19873574192
[mycoplasmas and pregnancy].the pathogenic role of mycoplasms during pregnancy remains quite controverted, depending on the studies; for some it has an incidence on prematurity, delayed growth in utero and premature rupture of the membranes. the purpose of this study was, from a population of patients with term delivery, without any specific pathology, to verify the frequency of mothers carrying mycoplasma hominis or ureaplasma, and to determine the possible consequences on the newborn. a linear analysis of the evolution o ...19873589355
prevalence and significance of mycoplasma hominis and ureaplasma urealyticum in the urines of a non-venereal disease population.ureaplasma urealyticum organisms (ureaplasmas) and mycoplasma hominis organisms (mycoplasmas) were sought in mid-stream urines collected from 200 men and 200 women attending hospital with conditions of a non-venereal nature. in addition, the urines from 100 male and 100 female healthy volunteers were examined. overall, ureaplasmas were isolated four times more often than mycoplasmas. in individuals less than 50 years of age, the organisms were found in about 20% of men and about 40% of women. in ...19873595751
a microbiologic and clinical study of placental inflammation at term.this study describes the relationships between histologically evident inflammation of the placenta, membranes, and umbilical cords, and correlates these lesions with clinical outcome and with amniotic fluid and amniotic membrane cultures in pregnancies at risk for clinical infection. the overall frequency of inflammation in 123 placentas was 85.45%. there were good interrelationships between inflammatory lesions at various sites. membrane infiltrates of 3+ were seen in 90.9% of intra-amniotic in ...19873601279
postcesarean wound infection by mycoplasma hominis in a patient with persistent postpartum fever.mycoplasma hominis was isolated in pure culture from a wound infection following delivery by cesarean section. the importance of recognizing this organism as a potential pathogen of the female genital tract is emphasized. two commercially available isolation systems that allow the recovery of this organism are also described.19873652655
[isolation of mycoplasma hominis from the blood in puerperal fever]. 19873614885
analysis of protein antigens of mycoplasma hominis: detection of polypeptides involved in the human immune response.immunoblotting of polypeptide antigens after polyacrylamide gel electrophoresis was used to analyze clinical strains of mycoplasma hominis. there was increased antibody titer for polypeptides comprising a wide range of molecular sizes between paired sera obtained from patients with indication of invasive infection. eight of these antigens were shown to be candidate surface antigens. absorption of hyperimmune rabbit serum with intact cells resulted in elimination or reduction in intensity of band ...19873667227
western blot analysis of the human serum response to mycoplasma hominis.mycoplasma hominis is a human genital pathogen with importance in postpartum pregnancy complications (postpartum fever/endometritis). previous research has suggested that serum antibody levels to m. hominis are important in predicting which groups of women are at risk. m. hominis strain pg21 was examined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sds-page) and western blots to determine which protein antigens would be good candidates for use in serologic tests. western blots o ...19873667228
an improved method for elimination of mycoplasmas from cell cultures.cell lines infected by different species of mycoplasma (mycoplasma orale, mycoplasma hominis) were decontaminated by co-culture with human blood monocyte (bm)-derived macrophages and pooled human immunoglobulin preparations. co-cultures with bm-derived macrophages or murine peritoneal macrophages (pm) alone were not successful. the phenotype of infected cell lines did not differ from that of uninfected cell lines as revealed by morphological, enzymecytochemical, and immunocytochemical analysis.19873668257
[biologic properties of ureaplasma urealyticum and mycoplasma hominis isolated from persons with inflammatory conditions of the urethra. ii. occurrence of ureaplasma urealyticum and mycoplasma hominis in healthy men and in those with inflammatory conditions of the urethra and in their sexual partners]. 19873669804
the role of mycoplasmas, ureaplasmas and chlamydiae in the genital tract of women presenting in spontaneous early preterm labour.the genital carriage of ureaplasma urealyticum, mycoplasma hominis and chlamydia trachomatis was assessed in 72 women admitted to hospital in spontaneous preterm labour and in 26 women requiring preterm delivery for other reasons who formed a control group. women in preterm labour significantly more often carried ureaplasmas, had large numbers of m. hominis and subsequently developed chorioamnionitis than women in the control group. m. hominis, in particular, occurred more frequently and in larg ...19873669058
mycoplasma hominis meningitis in a preterm infant. 19873668264
colonization with genital mycoplasmas in pregnant women and their neonates and birth weight.the colonization by genital mycoplasmas of mothers and their newborn infants was examined in 114 pregnant women and their 84 neonates. urine and cervical swabs were taken from the pregnant women in the last trimester, and urine from the neonates within six days after birth. ureaplasma urealyticum was found in 73.7% of the pregnant women and in 17.9% of the neonates. mycoplasma hominis was isolated in 8.8% of the material from the pregnant women and in 1.2% of that from the neonates. the isolatio ...19873673336
[biologic properties of ureaplasma urealyticum and mycoplasma hominis isolated from persons with inflammatory conditions of the urethra. i. a method of isolating ureaplasma and mycoplasma from human clinical specimens]. 19873669803
[incidence of mycoplasma hominis in women using an iud]. 19863714257
vaginal colonization with mycoplasma hominis and ureaplasma urealyticum.vaginal cultures obtained from unselected young women who consulted the gynecologist in a student health service were examined for ureaplasma urealyticum and mycoplasma hominis. each participant completed a confidential questionnaire. multiple logistic regression analysis was used to determine which variables, of a large number ascertained, were associated with mycoplasmal colonization. u. urealyticum was isolated from 273 (56.8%) of 481 participants. the following variables were significantly p ...19863715677
[incidence of ureaplasma urealyticum and mycoplasma hominis in persons examined for sterility]. 19863719732
prevalence of chlamydia trachomatis and other micro-organisms in women seeking abortions in pittsburgh, pennsylvania, united states of america.the prevalence of chlamydia trachomatis, ureaplasma urealyticum, mycoplasma hominis, group b streptococcus, herpes simplex virus, and neisseria gonorrhoeae from cervical cultures obtained from 210 women seeking abortion in pittsburgh, pennsylvania, united states of america was 9.3%, 72.9%, 25.2%, 4.3%, 0.9%, and 0.9% respectively. cultures from 40/203 (19.7%) patients failed to produce any of these organisms. c trachomatis isolation was not associated with age, race, marital status, average fami ...19863721515
genital mycoplasma colonization in neonatal girls.specimens obtained from the genital tract of 90 pairs of mothers and their female infants were cultured for ureaplasma urealyticum (ureaplasma) and mycoplasma hominis (m.hominis). ureaplasma and m.hominis were isolated from 80% and 17% of pregnant women, and 41% and 4.4% of female infants, respectively. fifty nine per cent of infants were positive for ureaplasma when they were borne per vaginam by ureaplasma-positive mothers. however, ureaplasma was not isolated from any of 11 infants delivered ...19863739634
hormonal status and mycoplasma colonization in the female genital tract.three hundred seventy-four cervical or vaginal specimens from patients with various hormonal states were cultured for ureaplasma urealyticum and mycoplasma hominis. significantly, low recovery rates of u urealyticum were obtained in the prepuberty (5%), puerperium (24%), and postmenopause (25%) groups, whereas pregnant women showed the highest incidence of u urealyticum (82%). the recovery rate of u urealyticum from neonates was 42%. the incidence of u urealyticum in sexually inactive females wa ...19863737042
clinical and microbiological investigation of women with acute salpingitis and their consorts.to determine the microbiological causes of pelvic inflammatory disease, 43 women with acute salpingitis (as) and 160 controls were studied. amongst as women there were significantly higher endocervical isolation rates of neisseria gonorrhoeae (54% vs 6%), chlamydia trachomatis (40% vs 13%), mycoplasma hominis (60% vs 19%), enterobacteria (26% vs 11%) and anaerobic bacteria (58% vs 29%). a polymicrobial pathogenic endocervical flora was present in both gonococcal and non-gonococcal as. laparoscop ...19863741814
treatment of sexually transmitted diseases.this paper outline the treatments of choice for sexually transmitted infections. current treatment recommendations for gonorrhea reflect the emergence of tetracycline-resistant neisseria gonorrhoeae and the increasing prevalence of penicillinase-producing strains that are resistant to penicillin. a single dose of amoxicillin is highly effectice against urethral or cervical gonorrhea caused by penicillin-susceptible strains; also effective is a new agent, ceftriaxone. however, neither of these ...19863754031
antimicrobial susceptibility testing of mycoplasma hominis. 19863759152
role of genital mycoplasmas in young infants with suspected sepsis.to establish the prevalence of mycoplasma hominis and ureaplasma urealyticum in infants up to 3 months of age with suspected sepsis, blood, cerebrospinal fluid, and urine specimens from 203 patients with clinical signs and symptoms of sepsis were cultured for mycoplasma in addition to routine bacterial cultures. proved bacterial infections were identified in 24 patients, four of whom had bacteremia. m. hominis and u. urealyticum were not isolated from any of the 191 blood and 199 csf specimens t ...19863783341
[the role of intrauterine contraceptive devices in the development of inflammatory processes in the small pelvis].the incidence of pelvic inflammatory disease (pid) attributable to iud use has been increasing, especially after the removal of the dalkon shield from the market, but this relationship has not been settled conclusively. in recent decades pid included a variety of infections, but lately the definition of pid has meant acute ascending infections of the female genital tract. its most common risk factors include promiscuity of iud use, although this can be reduced to one fourth by regular checkups ...19863763205
effect of carbohydrates on growth of ureaplasma urealyticum and mycoplasma hominis.we examined the effect of 31 carbohydrates on the growth of ureaplasma urealyticum and mycoplasma hominis. arbutin and its breakdown product, hydroquinone, inhibited growth of both species; the other substrates did not alter the extent of growth. volatile and nonvolatile end products of carbohydrate metabolism were not detected by gas chromatography.19873793871
chorionic mycoplasmas and prematurity.in this study, recovery of ureaplasma urealyticum and mycoplasma hominis from the freshly exposed chorion following delivery was related to labor length but not to the interval between membrane rupture and delivery, to birth weight or to gestational age.19863795198
ureaplasma urealyticum in the immunocompromised host.the lack of antibody in hypogammaglobulinemic patients probably results in failure of mycoplasmas to be "neutralized" and accounts for the diminished ability of the patients to cope with these organisms escaping hematogenously from the respiratory and urogenital tracts. furthermore ureaplasma urealyticum and other mycoplasmas are ingested by neutrophils in the absence of opsonins, indicated by the fact that they are able to trigger the release of chemiluminescence from these cells; ureaplasmas a ...19863797323
chorioamnionitis: its association with pregnancy outcome and microbial infection.in a study of 33 cases of perinatal death, chorioamnionitis was observed in 57.6% compared with 5% of 20 control cases (p less than 0.001) and in 70.8% of cases with no morphologic cause compared with 22.2% of cases with a defined cause of death (p less than 0.01). chorioamnionitis was significantly associated with previous gestations (p less than 0.01), prolonged rupture of the membranes (p less than 0.001), prematurity (20 to 27 weeks' gestation) (p less than 0.001), and low birth weight (less ...19873826174
measurement of antibody to mycoplasma hominis by an enzyme-linked immunoassay and detection of class-specific antibody responses in women with postpartum fever.the standard conditions for detection of human igg, igm, and iga antibodies to mycoplasma hominis by an enzyme-linked immunosorbent assay (elisa) were established with the use of a cell lysate antigen and alkaline phosphatase conjugates. antigen was used at a concentration of 10 micrograms of protein per milliliter, sera were diluted 1:200, and conjugates were diluted 1:500. agreement between cultured isolation of m. hominis from the lower genital tract and presence of antibody in 207 women was ...19873826222
a survey of mycoplasma detection in veterinary vaccines.nine live virus veterinary vaccines from six sources were found to be contaminated with mycoplasma. the vaccines were for use in canine, feline and avian species, and 53 batches of the products were at fault. the isolates were identified as mycoplasma hominis, m. arginini, m. orale, m. hyorhinis and m. gallinarum. investigation of the contamination rate of other batches or other products from the same source in some cases helped to determine the source of infection. mycoplasma contaminants can b ...19863799018
[role of mycoplasma hominis and ureaplasma urealyticum in the etiology of various diseases]. 19853835596
arginine deiminase of mycoplasma hominis: cytoplasmic and membrane-associated forms.membrane and cytoplasmic fractions of mycoplasma hominis inhibited the multiplication of this mycoplasma. arginine deiminase (ec 3.5.3.6), isolated from both fractions, reproduced the inhibition. the purified cytoplasmic deiminase had a subunit mr of 49,000, a specific activity of 53 units (mg protein)-1 and an a280/a260 ratio of 1.76. the membrane-associated enzyme had an identical mr but lower values for specific activity [39 units (mg protein)-1] and the a280/a260 ratio (1.46). in experiments ...19863806049
low birth weight, prematurity, and postpartum endometritis. association with prenatal cervical mycoplasma hominis and chlamydia trachomatis infections.we studied associations of mycoplasma hominis, ureaplasma urealyticum, and chlamydia trachomatis genital infections with pregnancy outcomes, controlling by logistic and multiple linear regression for known risk factors and for the presence of the other two infections. a sample of 1204 navajo women enrolling for prenatal care had endocervical c trachomatis, m hominis, and u urealyticum cultures and serum samples taken at enrollment and when possible after 30 weeks. low birth weight (less than 250 ...19873806917
a retrospective study of doxycycline in the treatment of genitourinary infections.a retrospective study was conducted to assess the prevalence of chlamydia trachomatis, ureaplasma ureolyticum, and mycoplasma sp in patients with suspected genital infection, and to assess the efficacy of doxycycline and other current antibiotic therapies. over a three-year period, 1,048 records of patients (64% female; 36% male) were reviewed. c trachomatis, u ureolyticum, or mycoplasma hominis was found in 39% of the men and 49% of the women. other pathogens included gardnerella vaginalis (in ...19863829089
prevalence of low genital tract infectious agents in young israeli women.low genital tract infectious agents were examined 411 times in 386 young women. each examination included anamnesis, physical examination and broad-spectrum microbiologic analysis for the detection of: ureaplasma urealyticum, chlamydia trachomatis, trichomonas vaginalis, candida species, mycoplasma hominis, streptococcus beta hemolyticus group b, hemophilus vaginalis, neisseria gonorrhoeae and syphilis serology. three hundred and six patients were symptomatic for low genital tract infection and ...19853873446
chlamydia trachomatis, mycoplasma hominis, and ureaplasma urealyticum infections of infants. 19853881828
serological evidence that chlamydiae and mycoplasmas are involved in infertility of women.women with a history of infertility for 2 or more years were examined by hysterosalpingography (hsg) and antibodies against chlamydia trachomatis, mycoplasma hominis and m. genitalium were measured by a microimmunofluorescence technique in sera obtained immediately before hsg. of 45 women with abnormal hsg findings, 15 (33%) had antibodies to c. trachomatis and 16 (35.5%) to m. hominis. in contrast, of 61 women with normal hsg findings, only 8 (13%) and 7 (11.5%) had antibodies to these micro-or ...19853881583
proteolytic activity of mycoplasmas and ureaplasmas isolated freshly from human saliva.mycoplasma and ureaplasma strains freshly isolated from human saliva were examined for proteolytic activity. all the strains tested (101 strains of mycoplasma salivarium, 97 strains of mycoplasma orale, and 3 strains each of mycoplasma hominis and ureaplasma urealyticum) decomposed horse serum proteins, bovine albumin, and casein. ten of the m. salivarium and 8 of the m. orale strains were tested for aminopeptidase activity as well, using l-leucine-p-nitroanilide as a substrate, and were shown t ...19853881657
invasiveness of salmonella typhimurium in hep-2 cell cultures pre-infected with mycoplasma hominis and mycoplasma orale.the influence of mycoplasma infection on the in vitro invasiveness of s. typhimurium in hep-2 cell cultures has been tested. two strains of arginine-utilizing mycoplasma species mycoplasma hominis and m. orale both seemed to inhibit the bacterial in vitro invasiveness. both the ratio of infected cells and the number of intracellular bacteria per cell were reduced in the mycoplasma-infected cultures.19853885679
chlamydia, mycoplasmas, ureaplasmas, and yeasts in the lower genital tract of females. comparison between a group attending a venereal disease clinic and a control group.162 women were investigated. group i consisted of 85 women, who were partners to men with non-gonococcal urethritis (ngu) or presented macroscopic signs of cervicitis; patients who had harbored neisseria gonorrhoeae were excluded from the study. group ii was a control group of 77 women without any complaints from the urogenital tract and with normal findings at pelvic examination. all the women were tested for infection with chlamydia trachomatis, mycoplasma hominis, ureaplasma urealyticum, and ...19853885669
women at risk for gonorrhea: comparison of rosaramicin and ampicillin plus probenecid in the eradication of neisseria gonorrhoeae, chlamydia trachomatis and genital mycoplasmas.rosaramicin is a macrolide antibiotic with activity against neisseria gonorrhoeae, chlamydia trachomatis, and the genital mycoplasmas ureaplasma urealyticum and mycoplasma hominis. its efficacy in the treatment of genital infections was evaluated and compared with that of single-dose ampicillin plus probenecid in women with known, or suspected, uncomplicated gonococcal infection. isolation rates for n. gonorrhoeae, c. trachomatis, u. urealyticum, and m. hominis were 72%, 44%, 95%, and 65%, respe ...19853890223
prophylaxis with lymecycline in induced first-trimester abortion: a clinical, controlled trial assessing the role of chlamydia trachomatis and mycoplasma hominis.a clinical, controlled trial was performed to study the effect of prophylaxis with lymecycline and the role of chlamydia trachomatis and mycoplasma hominis in postabortal genital infection. of 532 women who were to undergo first-trimester abortion, 269 were randomized to treatment with oral lymecycline (300 mg bid) starting 2 days before the abortion and continuing for a total of 7 days, and 263 were randomized to placebo treatment. the rate of postabortal infection was 9.3% in the antibiotic gr ...19853890229
[antibiotic sensitivity of mycoplasma pathogenic for man].human pathogen mycoplasmas (mycoplasma pneumoniae, mycoplasma hominis, ureaplasma urealyticum) are intrinsically resistant to antibiotics which inhibit the cell wall biosynthesis (beta-lactams, vancomycin, bacitracin), to polymyxins, rifamycins, sulfonamides, trimethoprim, 5-nitroimidazoles, nitrofurans and to presently available quinolones. these three species are moderately susceptible to aminoglycosides, susceptible to chloramphenicol and highly susceptible to tetracyclines. m. pneumoniae is ...19853892448
pelvic inflammatory disease, intrauterine contraception, and the conduct of epidemiologic studies.pelvic inflammatory disease (pid) has been described in the medical literature for more than a century as a specific entity. neisseria gonorrhoeae, chlamydia trachomatis, and mycoplasma hominis, along with bacteroides fragilis and other anaerobic bacteria, have been most frequently associated with pid. factors affecting the occurrence of pid have been extensively studied during the past two decades and include number of sexual partners, age, race, socioeconomic status, education, and contracepti ...19853916040
[genital mycoplasma infections].clinical and experimental investigations on the significance of mycoplasma hominis and ureaplasma urealyticum have revealed different and contradictory results. both germs are frequently discovered in young, sexually active persons. ureaplasma urealyticum might be the cause of some cases of non-gonococcal urethritis. m. hominis seems to be one causative agent of endometritis, salpingitis, parametritis and septicaemia after birth; we do not know yet, however, how often this may be the case. m. ho ...19853904251
the relation between vaginal ph and the microbiological status in vaginitis.the vaginal ph, microbial flora and presence of clue cells were investigated in 89 women who were seen at a sexually transmitted diseases clinic with a vaginal discharge or because they were contacts of men with gonococcal or non-gonococcal urethritis or because they were seeking a routine examination. none of the women had received antibiotics for at least 4 weeks before examination. a clinically normal vaginal secretion was found in 21 (55%) of 38 women who had a vaginal ph of 5.0-5.5, while s ...19853910080
antibodies to microbial, leukocyte and organ antigens.hemagglutinating antibodies to mycoplasma hominis were present in 30 of 83 infertile, 15 of 40 pregnant and 5 of 20 post-partum females and 20 of 82 infertile males in contrast to only 2 of 21 fertile females and 5 of 25 fertile males. their presence correlated with sperm antibody detection by tat in lab. 4, the immunobead-binding assay of lab. 1 and the sit of lab. 11, but not with other sperm antibody assays. immunofluorescent antibodies to chlamydia trachomatis, on the other hand, did not cor ...19853914551
prevalence and manifestations of endometritis among women with cervicitis.thirty-five women referred from a clinic treating sexually transmitted diseases, because of suspected cervicitis, were studied for the presence of endometritis by transcervical endometrial biopsies and cervical and endometrial cultures. fourteen (40%) of the patients had histologic evidence of endometritis. findings that significantly correlated with endometritis included a history of intermenstrual vaginal bleeding, the presence of chlamydia trachomatis, neisseria gonorrhoeae, or streptococcus ...19853923837
prevalence of antibodies to chlamydia trachomatis, neisseria gonorrhoeae, and mycoplasma hominis in infertile women.a total of 57 infertile women, who had been referred for in vitro fertilisation or for diagnostic laparoscopy, were tested for the presence of antibodies to chlamydia trachomatis, neisseria gonorrhoeae, and mycoplasma hominis. four were excluded from the study. of the remaining 53, 33 had laparoscopically obvious tubal disorders, such as adhesions, distal occlusions and strictures, and 20 did not. antibodies to c trachomatis were found in 7/33 (21.2%) v 0/20, antibodies to n gonorrhoeae in 20/38 ...19853924815
effects of mycoplasma hominis on in-vitro studies of neisseria gonorrhoeae.this study examined the effects mycoplasma hominis might have on neisseria gonorrhoeae. two auxotype standard strains of n. gonorrhoeae were found by culture and by light, fluorescence, and electron microscopy to be contaminated with m. hominis. in the presence of m. hominis, these strains of n. gonorrhoeae were typed as prototrophic. removal of the mycoplasmas by passage of the n. gonorrhoeae on serum-free medium resulted in a second change in growth requirements rather than a reversion to the ...19853929403
prosthetic joint infection with mycoplasma hominis. 19863941284
[comparative activity of minocycline and doxycycline on mycoplasmas pathogenic for man].susceptibility of mycoplasma pneumoniae (10 strains), mycoplasma hominis (20 strains) and ureaplasma urealyticum (100 strains) to minocycline and doxycycline was studied in vitro. minimal inhibitory concentrations were determined using an agar dilution method for m. pneumoniae and m. hominis and a metabolic inhibition test for u. urealyticum. m. pneumoniae strains were highly susceptible to minocycline and doxycycline (mic less than or equal to 0.1 mg/l). among m. hominis strains, 17 were suscep ...19853937130
recovery of microorganisms in semen and relationship to semen evaluation.semen samples from 120 consecutive unselected men attending our fertility clinic were studied to determine the bacterial isolation rate of semen and its influence on semen quality. each sample was cultured aerobically, anaerobically, and for ureaplasma urealyticum and mycoplasma hominis. the following were analyzed for each semen specimen: motility, morphologic features, and number of sperm cells and viscosity of the ejaculate. four of the 120 samples had negative results; 101 cultures yielded o ...19863943640
[prevalence of mycoplasma hominis and ureaplasma urealyticum in patients with impaired fertility]. 19863964000
infection with chlamydia trachomatis in female college students.chlamydia trachomatis was isolated from genital specimens from 21 (4.9%) of 431 female college students. antibody to c. trachomatis was found in the genital secretions of 52 (11.9%) of 437 women. multiple logistic regression analysis showed race, number of sexual partners, and use of barrier methods of contraception to be predictive of infection with c. trachomatis. logistic regression analysis found race, number of sexual partners, use of barrier methods of contraception, and presence of cervic ...19853964985
the effect of mycoplasma hominis and ureaplasma urealyticum on hamster egg in vitro penetration by human spermatozoa.the effects of some genital mycoplasmas on the in vitro penetration of human spermatozoa into the master egg were studied. ureaplasma urealyticum serotypes 4, 8, and 6 showed high interfering activity: 6.3% (p less than 0.01), 12.3%, and 14.5%, respectively, against the 55.6% penetration rate of untreated sperm. neither a cytotoxic effect of mycoplasmas on gametes nor a masking of the binding sites on the egg surface were demonstrated. in experiments carried out with u. urealyticum serotype 4, t ...19853965307
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