| quantitative and qualitative studies of gut flora in striped bass from estuarine and coastal marine environments. | examination of the intestinal contents of 130 striped bass (morone saxatilis) collected from the hudson river and long island sound during may to october 1981 showed that opportunistic fish pathogens--especially aeromonas hydrophila--predominated in samples from both locations. other isolates from both groups of striped bass included vibrio, pseudomonads, flavo-bacteria, alcaligenes, and enterics. small numbers of micrococcus, bacillus, corynebacterium, and acinetobacter were also isolated. tota ... | 1986 | 3735580 |
| natural killer cells in leukemogenesis. | in order to relate a reduced natural killer (nk) cell function to leukemogenesis, nk cells in the spleen and peritoneal exudate cells, with and without stimulation by corynebacterium parvum, were tested in mice of various strains after split dose irradiation and after leukemogenic treatment with butyl- and methylnitrosourea. the investigations included also mice submitted to non-leukemogenic irradiation (1 x 1.5 and 1 x 4.5 gy) and mice submitted to an additional treatment with hydrocortisone, w ... | 1986 | 3736113 |
| [corynebacterium sp. bacteremia in chronic renal insufficiency]. | | 1986 | 3736255 |
| [new etiologic aspects in septic urolithiasis]. | | 1986 | 3738032 |
| antitoxin antibody levels and the outcome of illness during an outbreak of diphtheria among alcoholics. | during an outbreak of diphtheria among alcoholics in göteborg, sweden, a study was made of the diphtheria-antitoxin antibodies in serum samples from 8 clinical cases and 36 carriers of toxin-producing corynebacterium diphtheriae. 33/36 carriers were antibody-positive and had antitoxin titres greater than 0.01 iu/ml, a level which is regarded as relative protective, while only 1/8 clinical cases had such a titre. this patient presented a mild illness with no complications. the results of the stud ... | 1986 | 3738434 |
| [antibiotic-resistant corynebacteria--a new problem of infection in immunosuppressed patients]. | corynebacterium species can normally be found on the skin and mucous membranes but rarely cause infections. they are sensitive to most antibiotics. two patients with severe aplastic anemia undergoing antilymphocyte globulin therapy developed septicemia with a highly antibiotic-resistant corynebacterium (jk-group) only sensitive to vancomycin. both patients had prolonged severe neutropenia, defects of the mucocutaneous barrier and intensive antibiotic treatment for gram negative infections. in bo ... | 1986 | 3738458 |
| serodiagnosis of inapparent caseous lymphadenitis in goats and sheep, using the synergistic hemolysis-inhibition test. | the synergistic hemolysis-inhibition (shi) test, a serologic test for the detection of infection with corynebacterium pseudotuberculosis, was applied to serum samples from 196 goats and 76 sheep, including animals both with and without c pseudotuberculosis abscesses. fifty-one of 52 (98%) goats and 27 of 28 (96%) sheep with abscesses caused by c pseudotuberculosis had seropositive titers. seropositivity continued on subsequent samplings, even after superficial lesions were completely healed. the ... | 1986 | 3740616 |
| activated macrophages demonstrate direct cytotoxicity, antibody-dependent cellular cytotoxicity, and enhanced binding of naegleria fowleri amoebae. | macrophages activated in vivo by injection of corynebacterium parvum or bacillus calmette-guérin caused direct cytolysis of the pathogenic free-living amoeba, naegleria fowleri, in vitro. amoebicidal activity was time and cell density-dependent but was not dependent on the presence of specific antibody. antibody-dependent cellular cytotoxicity for amoebae was also expressed by activated macrophages. resident and thioglycolate-elicited macrophages demonstrated low cytolytic activity under all con ... | 1986 | 3742615 |
| evaluation of .5% and 1% iodophor teat dips on commercial dairies. | two postmilking teat dips containing .5 and 1% iodine were evaluated for approximately 8 mo under conditions of natural exposure to mastitis pathogens on four commercial dairy farms. in the two herds using .5% iodophor, incidence of intramammary infection with staphylococcus aureus and streptococcus agalactiae was reduced 68.3 and 46.2%, respectively. when numbers of new infections with both pathogens were combined, efficacy for the .5% iodophor was 62.3%. in the two herds using 1% iodophor, inc ... | 1986 | 3745576 |
| ecology of rhodococcus (corynebacterium) equi in soil on a horse-breeding farm. | the ecology of rhodococcus (corynebacterium) equi in soil was studied on a horse-breeding farm. r. equi was cultured from soil at a depth of 0, 10, and 20 cm on the six sites of the farm at monthly intervals for 10 months from march to december of 1983. the highest numbers of r. equi were found in the surface soil. the mean number of bacteria in soil samples at every depth increased remarkably from 0 or 10(2) to 10(4) colony-forming units (cfu) g-1 of soil in the middle of april, and later decre ... | 1986 | 3750818 |
| [the conditions of ampicillin acylase production by as 1.586]. | | 1986 | 3751014 |
| [septicemia caused by arcanobacterium haemolyticum (corynebacterium haemolyticum) and streptococcus milleri]. | | 1986 | 3751438 |
| group jk diphtheroid bacteremia. the successive isolation of an antibiotic-susceptible and an antigenically different multi-resistant strain. | a 71-year-old man with a permanent, subcutaneously implanted, intra-cardial pacemaker suffered from prolonged bacteremia with an antibiotic-susceptible group jk diphtheroid rod. he died in spite of the formation of specific serum antibody and parenteral treatment with ampicillin, cephradine and gentamicin. a second multi-resistant, but otherwise similar group jk strain was isolated post-mortem from the aseptically removed pacemaker electrode tip. the susceptible and the multi-resistant strains d ... | 1986 | 3751582 |
| use of neomycin for treatment of rhodococcus equi pneumonia in foals. | | 1986 | 3753344 |
| bacteremia in narcotic addicts at the detroit medical center. ii. infectious endocarditis: a prospective comparative study. | for one year all narcotic addicts admitted to the detroit medical center with infectious endocarditis (74 cases) were compared with a control group of bacteremic addicts who had other infections (106 cases). endocarditis was caused by staphylococcus aureus (60.8% of cases), streptococci (16.2%), pseudomonas aeruginosa (13.5%), mixed bacteria (8.1%), and corynebacterium jk (1.4%). s. aureus endocarditis most frequently involved the tricuspid valve; streptococci infected left-sided valves signific ... | 1986 | 3755255 |
| effects of activation on lipoprotein lipase secretion by macrophages. evidence for autoregulation. | lipoprotein lipase (lpl) activity was measured in the media of cultured mouse peritoneal macrophages that were isolated after the intraperitoneal injection of inflammatory agents in order to yield a variety of states of activation. fully activated macrophages obtained from corynebacterium parvum-injected mice secreted very low levels of lpl when compared to unstimulated macrophages, while inflammatory and primed macrophages had increased lpl secretion. when inflammatory macrophages were incubate ... | 1986 | 3760780 |
| antibodies to cultured tumor cells detected in sera of renal cell carcinoma patients by a quantitative avidin-biotin method. | antibodies reacting with the tumor cell line rc-pa were measured by a quantitative avidin-biotin complex method. sera of renal cell carcinoma patients, patients with other types of cancer and healthy donors were analyzed. of 71 sera from renal cell carcinoma patients 67 (94 per cent) were classified as showing renal cell carcinoma, while 32 of 36 sera (89 per cent) from healthy subjects were classified as showing no renal cell carcinoma. four of 21 serum specimens (19 per cent) from individuals ... | 1986 | 3761433 |
| bronchoalveolar phagocytic cell response to pulmonary infection of mice with rhodococcus (corynebacterium) equi. | | 1986 | 3761775 |
| inhibition of wound healing by corynebacterium parvum. | corynebacterium parvum (c. parvum), an immunostimulant, was examined for its effects on wound healing in mice. animals injected intraperitoneally with c. parvum, 1400 micrograms 48 hr prior to wounding had significantly decreased wound strength at 5, 7, 11, 14, and 21 days after wounding compared to saline-injected controls (p less than 0.05-p less than 0.001). mice injected with c. parvum at 48 or 2 hr before wounding, synchronous with wounding and 2 or 48 hr after wounding had significantly de ... | 1986 | 3762128 |
| [immunotherapy with corynebacterium parvum in experimental influenza virus infections and mixed infections in mice]. | | 1986 | 3763446 |
| [staphylococci in skin microbiocenosis of the breasts in healthy women]. | the autoflora of different anatomical regions of the mammary glands in 120 healthy nulliparous women aged 18-24 years was studied by p. williamson and a. m. kligler's methods of smears and washings. from the nipple, the areola, and the adjacent region of the skin 2,248 strains of anaerobic microorganisms were isolated; of these, 63.83% were staphylococci and micrococci, 6.01% were streptococci, 1.91% were neisseria, 17.79% were corynebacterium, 3.87% were bacilli, 2.8% were enterobacteria, and 3 ... | 1986 | 3765971 |
| diabetic foot infections. bacteriologic analysis. | diabetic patients with foot infections were prospectively evaluated over a two-year period. cultures from reliable specimens avoiding contamination with foot ulcers were obtained in 54 infectious episodes. staphylococcus species, enterococcus species, corynebacterium species, and various species of enterobacteriaceae were commonly isolated. common anaerobic isolates included peptostreptococcus magnus, peptostreptococcus prevotii, and bacteroides species. results of cultures from 94 unreliable sp ... | 1986 | 3767539 |
| elisa for toxinogenesis identification in corynebacterium diphtheriae, diagnostic value. | | 1986 | 3767639 |
| aspects of pathogenesis in a mouse model of infection by corynebacterium pseudotuberculosis. | a new medium, nutrient tween 80 broth (ntb) was utilised to achieve improved cultivation of corynebacterium pseudotuberculosis. twenty four hour ntb cultures were used for cutaneous and intraperitoneal infection of mice. the intraperitoneal administration of heterologous protein, liquid paraffin or thioglycollate prior to intraperitoneal challenge caused enhanced multiplication of the organism although this could be prevented by modifying host response. pretreatment of skin with thioglycollate e ... | 1986 | 3767763 |
| corynebacterium parvum followed by chemotherapy (actinomycin d and dtic) compared with chemotherapy alone for metastatic malignant melanoma. | seventy-nine patients with stage iii widely metastatic melanoma were prospectively randomised to a 'no treatment' control group who received on tumour progression dtic (250 mg/m2 i.v. daily x 5) and actinomycin d 1.5 mg/m2 on day 1. a total of six courses at 3-week intervals was given. chemotherapy was only given on progression of disease. the other group received initially corynebacterium parvum (2 mg/m2) every 3 weeks for a maximum of eight courses and then the same chemotherapy on evidence of ... | 1986 | 3770045 |
| monoclonal antibodies specific for corynebacterium sepedonicum, the causative agent of potato ring rot. | balb/c mice were immunized with corynebacterium sepedonicum, and spleen cells from the immunized animals were fused with cells of the mouse myeloma line p3-x63-ag8.653. several hybridoma cell cultures were selected for further study. monoclonal cs-b-5 was specific for c. sepedonicum and did not react significantly with other closely related phytopathogenic corynebacteria in an enzyme-linked immunosorbent assay (elisa). as few as 10(3) organisms could be detected. this approach should prove usefu ... | 1986 | 3770774 |
| production of trans-o-hydroxybenzalpyruvate from 1,2-dihydroxynaphthalene by cell-free extracts of corynebacterium renale. | | 1986 | 3770791 |
| [the significance of "nonpathogenic" corynebacteria as a cause of opportunistic infections]. | a lot of corynebacterial species, summarized as "diphtheroids" has its normal habitat on the human skin. consequently, these bacteria are often isolated from various clinical materials and mostly regarded as indeginous flora. the same bacteria, however, can cause serious infections, when the balance between host and microorganisms is impaired. multiresistant corynebacteria group jk are used as an example to describe the development of such infections. central venous catheters and other plastic d ... | 1986 | 3770798 |
| detection of corynebacterium kutscheri in animal tissues by dna-dna hybridization. | corynebacterium kutscheri, a pathogen of experimental rats and mice, is difficult to detect in the early stages of infection. a diagnostic assay was developed to reveal the organism in tissues of asymptomatic, infected animals. three fragments of dna specific to c. kutscheri were isolated, radiolabeled with 32p, and used in dna-dna hybridization assays with blots of impression smears of animal tissues on membrane filters. the c. kutscheri probes did not cross-hybridize with 15 dna isolates from ... | 1986 | 3771763 |
| bacterial and mycotic otological infections in singapore. | this paper describes a microbiological study of 84 young adult men with clinical otitic infections. gram-negative aerobic bacilli were frequently isolated from these patients diagnosed as having otitis externa or chronic suppurative otitis media, of which pseudomonas species predominated. staphylococcus aureus, s. epidermidis and aerobic corynebacterium species (diphtheroids) were also found. about 40% of ear infections were attributed to otomycoses, chiefly from aspergillus species and candida ... | 1986 | 3782787 |
| tonsillitis and rash associated with corynebacterium haemolyticum. | | 1986 | 3782868 |
| corynebacterium haemolyticum as a cause of nonstreptococcal pharyngitis. | | 1986 | 3782869 |
| bacteremia during bronchoalveolar lavage. | we prospectively evaluated the incidence of bacteremia during fiberoptic bronchoalveolar lavage (bal) and its relationship to postlavage symptoms in 12 volunteers. qualitative and quantitative blood cultures were obtained before and during bal. three persons had qualitative blood cultures positive for organisms typical of normal skin flora. quantitative blood cultures done simultaneously were negative. approximately 42% of our subjects had postlavage symptoms, but no correlation was found betwee ... | 1986 | 3787285 |
| the ultrastructure of antibiotic-susceptible and multi-resistant strains of group jk diphtheroid rods isolated from clinical specimens. | two antibiotic-susceptible and two multi-resistant strains of diphtheroid rods of the group jk, obtained from clinical specimens in denmark and from cdc in the u.s. were studied. the cells of all four strains presented an ordinary gram-positive cell wall and an additional surface layer. septum formation in dividing cells appeared to result in a "snapping-like" dividing mechanism, thus corroborating the relationship of the jk cells to the genus corynebacterium. a significantly increased thickness ... | 1986 | 3788571 |
| bacterial sarcosine oxidase: comparison of two multisubunit enzymes containing both covalent and noncovalent flavin. | sarcosine oxidase was purified to homogeneity from corynebacterium sp. p-1, a soil organism isolated by a serial enrichment technique. the enzyme contains 1 mol of noncovalently bound flavin [flavin adenine dinucleotide (fad)] plus 1 mol of covalently bound flavin [8 alpha-(n3-histidyl)-fad] per mole of enzyme (mr 168,000). the two flavins appear to have different roles in catalysis. the enzyme has an unusual subunit composition, containing four dissimilar subunits (mr 100,000, 42,000, 20,000, a ... | 1986 | 3790506 |
| quantitative fecal culture for early diagnosis of corynebacterium (rhodococcus) equi enteritis in foals. | quantitative culture of corynebacterium (rhodococcus) equi from feces of 17 foals on a farm (a) with an endemic c. equi infection problem and 26 foals on a farm (b) without the disease in the past decade was done with a selective medium at weekly or monthly intervals from april to august of 1984. corynebacterium equi was observed in the feces of 16 of 17 foals on farm a, and 19 of 26 foals on farm b. the mean viable count of c. equi in one gram of feces was 4.1 +/- 3.7 (log10) on farm a, and 3.9 ... | 1986 | 3791074 |
| discovery of a cutinase-producing pseudomonas sp. cohabiting with an apparently nitrogen-fixing corynebacterium sp. in the phyllosphere. | a phyllospheric bacterial culture, previously reported to partially replace nitrogen fertilizer (b. r. patti and a. k. chandra, plant soil 61:419-427, 1981) was found to contain a fluorescent pseudomonas which was identified as pseudomonas putida and a corynebacterium sp. the p. putida isolate was found to produce an extracellular cutinase when grown in a medium containing cutin, the polyester structural component of plant cuticle. the corynebacterium sp. grew on nitrogen-free medium but could n ... | 1987 | 3793714 |
| corynebacterium striatum: an unusual organism isolated in pure culture from sputum. | | 1986 | 3794367 |
| characterization of corynebacterium group jk by whole-cell protein patterns. | a total of 102 strains received as corynebacterium 'group jk' were characterized by sds-page of their whole-cell proteins. numerical taxonomy based on the protein pattern absorbance profiles indicated that 91 of the strains formed a cluster. seventy strains isolated in the uk were identified as group jk, indicating the increasing detection of this group as opportunistic pathogens. fine differences between strain patterns were visible but it was not possible to associate these with any particular ... | 1986 | 3794641 |
| corynebacterium group d2 pyelonephritis. | we believe this represents the first known case of group d2 pyelonephritis in a seventy-two-year-old white man. previous to this report d2 organisms have been associated only with alkaline-encrusted cystitis and struvite stones in urology. | 1987 | 3798634 |
| septicemia, rash, and pulmonary infiltrates secondary to corynebacterium group jk infection. | this report describes a leukemic patient undergoing induction therapy in whom a corynebacterium jk infection developed while he was leukopenic. the clinical triad of perirectal inflammation, skin lesions, and interstitial lung infiltrates, which has not previously been reported, is discussed. characteristics of the organism and postulated routes of infection as well as treatment are explored. | 1987 | 3799671 |
| pathogenesis of caseous lymphadenitis in sheep and goats. | the progress of caseous lymphadenitis in sheep and goats is described as involving primary wound infection, lymphatic and haematogenous dissemination, and secondary infection of lymph nodes and various visceral organs. this is followed by elimination or containment of infection, the latter being represented by the characteristic caseous lesions. resistance to infection is complex involving components of both the specific and non-specific host response. the role of these in pathogenesis is discus ... | 1986 | 3800800 |
| canine oral melanoma: comparison of surgery versus surgery plus corynebacterium parvum. | eighty-nine dogs with malignant oral melanoma were selected for study. all dogs were clinically staged and treated with either surgical excision alone or surgery plus c. parvum immunotherapy. there was no difference in survival time between the two treatment groups. however, in dogs with advanced disease (stages ii, iii) there was a statistical difference between surgery alone versus surgery plus c. parvum (p = 0.01). dogs with stage i disease (tumor less than 2 cm diameter) had a statistically ... | 1986 | 3801954 |
| serological surveys of corynebacterium kutscheri infection in mice and rats. | serological surveys of mice and rats naturally infected with corynebacterium kutscheri were performed by examining serum samples collected from breeder and laboratory colonies between 1981 and 1983. among 756 mice from 73 conventional colonies, only 4 animals (0.5%) from 3 colonies (4.1%) developed c. kutscheri antibody of 1:40 to 1:2, 560 titers. three of them suffered from abscess caused by the organism. regarding a titer of 1:40 or higher as reliably positive, 87 (13.0%) of 669 conventional r ... | 1986 | 3803435 |
| naturally occurring iga antibodies to ocular and oral microorganisms in tears saliva and colostrum: evidence for a common mucosal immune system and local immune response. | in this study, levels of naturally occurring secretory iga (siga) antibodies to bacterial isolates representative of the microflora of the human eye (staphylococcus epidermidis and a corynebacterium species) and the oral cavity (streptococcus mutans serotypes c and d) were assessed in three different human external secretions. tears and parotid saliva samples collected at the same time from 22 healthy subjects and colostrum from 11 healthy women (1-14 days post partum) were assessed for siga ant ... | 1986 | 3803459 |
| endocarditis caused by corynebacterium sp in a dog. | mitral valve bacterial endocarditis, caused by corynebacterium sp, was diagnosed in a dog. the bacteria had characteristics unlike those commonly recognized for most species of corynebacterium. the primary source of bacteremia was suspected to be a pilonidal cyst of the sacrum. the dog was treated with a first-generation cephalosporin for 6 weeks, and the pilonidal cyst was surgically removed. physical examination 1 year after initial examination revealed no abnormalities other than a cardiac mu ... | 1986 | 3804839 |
| structural abnormalities of the hair shaft. | abnormalities of the hair shaft are varied and often confusing. they do require accurate recognition, which can be helpful in the diagnosis and management of a hair disorder, or in the detection of underlying disease. a reliable evaluation of hair shaft abnormality is dependent on familiarity with the vast structural variations in normal hair, the hair growth cycle, and the changes produced by weathering. these structural abnormalities can be congenital or acquired, and some are associated with ... | 1987 | 3805378 |
| local interferon induction by bacterial lipopolysaccharide in mice after pretreatment with corynebacterium parvum. | c57bl/6 mice were injected intraperitoneally (i.p.) with corynebacterium parvum and subsequently, after an interval of 7-10 days, i.p. with lipopolysaccharide (lps). the peritoneal wash-fluid was recovered at various times after injection of lps. marked interferon (ifn) titers were observed between 2 and 10 h after injection of lps, whereas no ifn was detected in mice injected with either c. parvum or lps alone. very low doses of lps (0.1 microgram/mouse) were sufficient to cause ifn production ... | 1986 | 3805784 |
| superiority of intravesical immunotherapy with corynebacterium parvum and allium sativum in control of murine bladder cancer. | intravesical immunotherapy with bacillus calmette-guerin (bcg), corynebacterium parvum (cp), keyhole limpet hemocyanin (klh), and an extract of allium sativum (as) was studied in mice transplanted intravesically with mouse bladder tumor cells (mbt-2). female c3h/he mice were anesthetized with sodium pentobarbital. two x 10(5) mbt-2 cells were delivered into the bladder transurethrally using a small catheter, immediately after the posterior wall of the bladder had been electrocauterized. bladder ... | 1987 | 3806842 |
| [etiology and chemotherapy of suppurative surgical infection in horses and cattle]. | a total of 24 horses and 42 cattle with a variety of local suppurative processes (wounds, abscesses, phlegmons, tendovaginitis, etc.) were studied under conditions of the clinic with regard to the most commonly found microbial species and the opportunity to work out antibioticogrammes in terms of the effectiveness of 11 of the chemotherapeutic agents widely used in the practice. it was found that prevailing in horses were staphylococci and streptococci. in cattle corynebacterium pyogenes was pre ... | 1986 | 3811221 |
| bactericidal activity and killing rate of serum in volunteers receiving ciprofloxacin alone or in combination with vancomycin. | ten healthy volunteers received the following regimen on different days: vancomycin, 500 mg intravenously; ciprofloxacin, 200 mg intravenously; vancomycin plus ciprofloxacin. concentrations in serum measured microbiologically at the end of infusion and 1 and 6 h after the end of infusion were, respectively (mean [standard deviation] in milligrams per liter): 32.3 (5.5), 14.2 (2.6), and 4 (0.9) for vancomycin and 3.12 (0.86), 0.78 (0.18), and 0.19 (0.05) for ciprofloxacin. vancomycin concentratio ... | 1986 | 3813515 |
| in vitro activity of ci-934 and other antimicrobial agents against gram-positive and gram-negative bacteria. | the activity of ci-934, a new carboxy-quinolone antibiotic, against gram-positive cocci and bacilli and gram-negative bacilli was compared with that of reference antibiotics. ci-934 demonstrated excellent activity against gram-positive organisms, including corynebacterium sp. in addition, although the activity of ci-934 against gram-negative bacilli was less than that reported for similar agents, it was comparable to that of aminoglycosidic aminocyclitol antibiotics. | 1986 | 3815456 |
| proliferative glomerulonephritis and chronic active hepatitis with cirrhosis associated with corynebacterium parvum immunotherapy in a dog. | | 1987 | 3818425 |
| corynebacterium endocarditis. difficult diagnosis in an elderly woman. | physicians have been reminded repeatedly of the many faces of bacterial endocarditis. in this case, corynebacterium endocarditis presented as an occult malignancy and eluded diagnosis for six months. the coryneform isolates found in cultures are often considered to be contaminants because of their ubiquitous nature, sometimes causing a delay in diagnosis. patients with culture-negative endocarditis or corynebacterium "contamination" should be treated as having corynebacterium endocarditis pendin ... | 1987 | 3822964 |
| [pseudotuberculosis in goats also in the netherlands. a literature review]. | pseudotuberculosis or caseous lymphadenitis in goats is marked by superficial abscesses and was recently observed in the netherlands. the literature on this disease is reviewed, concerning the incidence, aetiology, pathogenesis, symptoms, diagnosis, therapy and preventive measures. the damage which the disease could cause to goat husbandry in the netherlands, is discussed. although the losses from death and diminished production will probably be small, treatment is time-consuming and requires mu ... | 1987 | 3824355 |
| corynebacterium hemolyticum bacteremia with fatal neurologic complication in an intravenous drug addict. | a 50-year-old intravenous drug user presented with clinical features suggestive of mitral valve endocarditis. blood culture specimens grew corynebacterium hemolyticum. despite treatment with penicillin, he died from a neurologic complication. recognition of the pathogenic potential of nondiphtherial coryneforms in non-immunocompromised hosts is important. | 1987 | 3826127 |
| corynebacterium hemolyticum and pharyngitis. | | 1987 | 3826967 |
| effect of anti-inflammatory drugs on the production of tumour necrosis factor and lipopolysaccharide induced-mortality in mice. | mice injected with viable listeria monocytogenes or powdered corynebacterium parvum and challenged with endotoxin released tumour necrosis factor (tnf) into the blood. however, the rate of mortality from endotoxin shock was high. administration of the non-steroidal anti-inflammatory drugs acetylsalicylate, indomethacin and phenylbutazone protected the animals against the lethal effect of endotoxin without affecting the ability of animals to produce tnf. the significance of these observations are ... | 1987 | 3828981 |
| correlation of in vitro properties of rhodococcus (corynebacterium) equi with virulence for mice. | to study the virulence of rhodococcus (corynebacterium) equi, seven atcc strains of different serotypes were tested for their ld50 in mice, clearance of the organism from the lungs and spleen following intravenous or intratracheal inoculation, and in vitro interaction with murine peritoneal macrophages. strains atcc 33704 and 33705 were virulent for mice and multiplied in the lungs and spleen, resulting in death of the animal in 5 days. the other five strains were avirulent for mice. the number ... | 1985 | 3831718 |
| an abbatoir survey of the prevalence of caseous lymphadenitis in feral goats in western australia. | | 1985 | 3834907 |
| a study of tail tip necrosis in young fattening bulls on slatted floors. | a questionnaire sent to 78 producers revealed that tail tip necrosis was seen only in units with fattening bulls housed on slatted floors. out of 43 such units, 20 (46.5 per cent) reported that tail tip necrosis was a herd problem. all 43 herds were visited, owners were interviewed and housing and management data recorded. it is concluded that tail tip necrosis is a multifactorial disease. the initial lesion is caused by tramping, but the following factors are essential in the development and se ... | 1985 | 3835543 |
| immunogenicity of corynebacterium pseudotuberculosis and the effect of adjuvants in mice. | intraperitoneal inoculation of cf1 mice with 100 micrograms, 200 micrograms, or 300 micrograms whole cell (wc) or 250 micrograms, 500 micrograms, or 1000 micrograms cell wall (cw) of corynebacterium pseudotuberculosis induced varying degrees of protection after intravenous challenge of immunity with 7.2 x 10(4) cfu of c. pseudotuberculosis. generally, the degree of protection increased with the dose of wc or cw. however, intraperitoneal inoculation of mice with 100 micrograms, 200 micrograms, or ... | 1985 | 3837788 |
| the pathogenesis of a high-virulence and a low-virulence strain of corynebacterium bovis in the mammary gland of the mouse. | a comparison was made of the pathogenesis of experimental mastitis in mice caused by a strain of corynebacterium bovis (p3) isolated from clinical mastitis in the cow and a strain (ncdo 1930) isolated from the teat of a symptomless carrier cow. strain ncdo 1930 elicited a neutrophil response which controlled the infection so that, after 6 to 8 days, 9 of 10 glands were sterile and one abscess was found. in contrast, the neutrophil response to strain p3 failed to control the infection and, by 6 t ... | 1985 | 3837793 |
| intertriginous dermatoses. common puzzling problems. | physical examination of the skin is the most important step in differentiating intertriginous dermatoses. once the eruption is recognized as a primarily intertriginous problem, the diagnostic possibilities are comparatively limited. determination of the primary lesion (eg, blister, scale, nodule), together with some history and simple diagnostic tests, can usually pinpoint the specific diagnosis. | 1985 | 3840592 |
| [antitumoral activity of various doses of corynebacterium parvum as a function of the age of mice]. | the anti-tumor activity of corynebacterium parvum against two different tumours, a mammary carcinoma grafted in c3h mice and a lymphosarcoma grafted in xvii mice, was lower in young and old mice, than in adult ones. in young mice (25 days) of both lines, low doses of c. parvum were more efficient than higher doses. in 12-month old xvii mice a higher survival rate was obtained by increasing the dose of c. parvum administered, whereas in old c3h mice, this phenomenon was not observed. sublethal do ... | 1985 | 3840664 |
| a sustained increase of microsomal heme oxygenase activity following treatment of rats with bacillus calmette-guerin and corynebacterium parvum: its possible relation to the decrease of cytochrome p-450 content. | the alterations of various enzymes responsible for drug metabolism and heme metabolism were examined in the liver of female rats treated with bacillus calmette-guerin (bcg) and corynebacterium parvum (cp). hepatic drug metabolizing enzyme activities and microsomal cytochrome p-450 and b5 content were significantly decreased for up to 15 and 10 d by a single i.v. administration of bcg and cp, respectively. in contrast, microsomal heme oxygenase activity was markedly increased after bcg and cp tre ... | 1985 | 3841363 |
| physiological and pathological factors influencing bovine alpha-lactalbumin and beta-lactoglobulin concentrations in milk. | bovine alpha-lactalbumin and beta-lactoglobulin concentrations were determined by radial immunodiffusion in 354 milk samples from uninfected and 98 samples from infected quarters from 42 holstein-friesian cows taken at 30, 150, and 270 days of lactation. alpha-lactalbumin and beta-lactoglobulin concentrations were not affected by quarter location. the alpha-lactalbumin decreased at the end of lactation and in samples collected beyond second lactation. the beta-lactoglobulin concentration increas ... | 1985 | 3842846 |
| factor b, the complement alternative pathway serine proteinase, is a major constitutive protein synthesized and secreted by resident and elicited mouse macrophages. | factor b, the complement alternative pathway serine proteinase, a class iii gene product of the major histocompatibility complex, is a major constitutive secretion product of mouse mononuclear phagocytes. this glycoprotein was synthesized and secreted by macrophages as a doublet of mr 90,000 and 93,000 polypeptides that were immunoprecipitable with antibodies raised to human serum factor b, and that were indistinguishable from plasma factor b by immunoreactivity, peptide mapping, and molecular w ... | 1985 | 3844438 |
| development of hyporesponsiveness of natural killer cells to augmentation of activity after multiple treatments with biological response modifiers. | four biological response modifiers (brms), mve-2 (maleic anhydride divinyl ether), corynebacterium parvum (c. parvum), polyiclc (polyinosinic:polycytidylic acid stabilized with poly-l-lysine), and mouse alpha beta-interferon (alpha beta-ifn), were tested to assess whether repeated treatments would repeatedly induce or sustain augmented levels of natural killer (nk) cell activity and/or macrophage (m0)-mediated inhibition of tumor cell growth. in contrast to a significant increase in splenic nk a ... | 1985 | 3845849 |
| [trichomycosis-erythrasma]. | | 1985 | 3847132 |
| evaluation of in vivo and in vitro effectivity of immune defense against a spontaneously arising, nonlymphoid rat tumor. i. analysis of natural immune defense. | possible mechanisms of natural defense against a nonimmunogenic, nonlymphoid rat tumor were evaluated in vitro and examined for effectivity in vivo, using bsp6s, the subcutaneously grown transplantation line of a spontaneously arising fibrosarcoma in the bdx rat strain, which is highly susceptible to natural killer (nk) cells and macrophages (mø). the role of nonspecific immune defense in vivo was demonstrated by eliminating nk cells by irradiation and mø by silica treatment. especially after de ... | 1985 | 3847288 |
| comparative activity of the penem antibiotic sch 34343 against gram-negative and gram-positive bacteria with special reference to multiresistant strains. | a new penem antibiotic, sch 34343, was shown to be active against a large number of gram-positive bacteria. the drug inhibited penicillinase-positive and -negative staphylococci equally well, being five times more active than cefamandole and ten times more active than methicillin. most methicillin-resistant staphylococci were inhibited by concentrations between 0.25 and 4 mg/l, but a small group of highly resistant strains were observed. sch 34343 was eight times less active than ampicillin and ... | 1985 | 3849537 |
| natural killer inhibitory substance produced by the peritoneal cells of patients with ovarian cancer. | peritoneal cells obtained from 8 patients with minimal residual ovarian cancer produced a substance during in vitro culture that markedly inhibited the expression of natural killer (nk) cell-mediated lysis. its molecular weight was less than 2,000, the same size as the nk-inhibiting substance (nk-is), a similar nk-suppressive molecule produced by the peritoneal cells of rats. human nk-is suppressed the expression of antibody-dependent cell cytotoxicity as well as nk lysis, but it had no effect o ... | 1985 | 3856049 |
| stimulation of proliferation in mixed cultures of mouse tumor cells and nonimmune peritoneal cells. i. occurrence of stimulation and cyclical variation in tumor cell activity. | mixtures of mouse tumor cells and resident peritoneal cells (pc) from nonimmune mice frequently incorporated [methyl-3h]thymidine [( 3h]dthd) in culture to a far greater extent than did either cell population alone. with pc-to-tumor cell ratios of 10:1, stimulation indices of up to 21 were recorded. syngeneic, semisyngeneic, and allogeneic mixtures were active. pc elicited by thioglycollate or proteose-peptone could participate in the reaction. pc from mice injected with corynebacterium parvum a ... | 1985 | 3856066 |
| effects of murine tumor necrosis factor on friend erythroleukemic cells. | tumor necrosis inducing factor (tnf), a 140,000 molecular weight glycoprotein present in the serum of corynebacterium parvum endotoxin-treated mice, was cytotoxic toward friend virus-transformed erythroleukemic cells (felc). these cells grow in culture as undifferentiated pro-erythroblasts but can be induced to differentiate in a limited fashion along the erythroid pathway to orthochromatic normoblasts by various agents such as dimethylsulfoxide (dmso). partially and highly purified preparations ... | 1985 | 3856542 |
| immunomodulation of nk and adcc by corynebacterium parvum in acute myeloid leukaemia patients. | natural killer (nk)- and antibody dependent cellular cytotoxicity assays were performed using cryopreserved effector cells in aml patients receiving i.c. and s.c. injections of corynebacterium parvum. a dose related increase in nk could be demonstrated with peaks in nk at day 1 with full cp dosage and at day 14 with 50% doses. this increase was attributable to the cp vaccine since normal donors receiving tetanus toxoid or pneumococcal polysaccharide and aml patients randomized not to receive cp ... | 1985 | 3857405 |
| corynebacterium pseudotuberculosis abscesses in a young butcher. | | 1985 | 3859276 |
| selectively eliminated blood monocytes and splenic suppressor macrophages in mice depleted of bone marrow by strontium 89. | the contribution of specific activity to the effects of the bone-seeking isotope, strontium 89 on radiosensitive components of mononuclear phagocyte populations was investigated in mice. cba/j mice received a fixed dose of 2 microci/g body weight of 89sr with three different specific activities, 6 ci, 100 microci and 20 microci per mg sr. the estimated radioactivity located in the bone surface was 4,200, 3,000 and 2,400 cpm/mg bone when measured 2 days after the administration of 89sr, and was l ... | 1985 | 3864908 |
| establishment of growth factor-dependent mopc 104e cell line in vitro. | the mopc 104e cell line has been adapted to grow in vitro using a combination of feeder layer and growth factor(s). the growth of this myeloma cell line is dependent on the presence of growth factor(s). growth-promoting activity generated from t-cell-mitogen-stimulated, corynebacterium parvum-stimulated spleen cell culture supernatant, and peritoneal adherent cell culture supernatants gives dose-dependent proliferation. generation of growth factors in the serum-free bovine serum albumin-substitu ... | 1985 | 3871362 |
| adoptive immunotherapy of newly induced murine sarcomas. | two newly induced methylcholanthrene sarcomas of c57bl/6 mouse origin were selected for studies of the adoptive immunotherapy of established tumors. the mca 105 and mca 106 tumors, used during their first five transplant generations, possessed weakly immunogenic tumor-associated transplantation antigens as revealed by failure to elicit immunity to reject 10(6) tumor cells by tumor growth and excision. specific immunity to reject a 10(6) tumor cell challenge could be elicited in less than 50% of ... | 1985 | 3872168 |
| effects of immunization of mothers on the immune reaction of their offspring. ii. significance of enhanced antigen elimination by maternal antibodies on the suppression of the offspring. | in the offspring of sheep erythrocyte (srbc)- or chicken erythrocyte (crbc)-immunized mothers, generation of cytotoxicity and plaque forming cells (pfc) were suppressed, while delayed-type hypersensitivity (dth) was not. we performed experiments to analyse the mechanism of this suppression. antigen specific antibodies, which enhanced opsonization or antibody-dependent cell-mediated cytotoxicity (adcc), might have a close relation to the suppression (1). the suppression was weakened by a high-dos ... | 1985 | 3872371 |
| carbenicillin-hydrolyzing beta-lactamase produced by corynebacterium pseudodiphtheriticum. | | 1985 | 3876322 |
| the effect of treatment with corynebacterium parvum on the development and growth of experimental hematogenic metastases of schwannoma in the rat. | single i.v. administration of corynebacterium parvum 5 days before i.v. injection of 10(6) tissue cultured syngeneic schwannoma cells in lewis rats resulted in extension of survival time (p less than 0.05). there was a significant decrease in metastatic tumor incidence for lung, heart, and kidney and decreased lung tumor growth with approximately 50% of the lung tumor burden of untreated controls (p less than 0.05). rats treated similarly with c. parvum 10 days after tumor cell injection showed ... | 1985 | 3876679 |
| diphtheritic septicaemia and probable endocarditis: a case report and review of the literature. | corynebacterium diphtheriae usually produces an infection limited to the respiratory tract and the organisms rarely invade the blood stream. we report the case of a 6-year-old girl who, 2 months after an unsuccessful repair of a ventricular septal defect, developed septicaemia with non-toxigenic c. diphtheriae. the organism appeared resistant to penicillin in vitro and failed to respond to a course of trimethoprim-sulfamethoxazole to which it was susceptible in the laboratory. a cure was finally ... | 1985 | 3878295 |
| disease patterns in the detroit zoo: a study of the mammalian population from 1973 through 1983. | a retrospective study was conducted to evaluate disease patterns in the mammals at the detroit zoo from 1973 through 1983. the reindeer (rangifer tarandus), common eland (taurotragus oryx), rednecked wallaby (protemnodon rufogrisea), sitatunga (tragelaphus spekii), and kangaroo (macropus spp)- were the most frequently affected mammalian species. parasitic agents (80% of which were internal parasites) caused morbidity in 60.2% of the mammals evaluated (n = 2,475) and microbial agents caused morbi ... | 1985 | 3878354 |
| in vitro generation of procoagulant activity by corynebacterium parvum-stimulated mononuclear leukocytes. | thromboembolic complications are known in cancer patients after i.v. administration of corynebacterium parvum. we examined the ability of this organism to induce production of procoagulant activity by human blood mononuclear leukocytes in vitro. after 4 hours incubation corynebacterium parvum was an effective stimulant for mononuclear leukocytes, behaving in the same way as the typical gram-negative bacterium escherichia coli, whereas mononuclear cells incubated with staphylococcus aureus were n ... | 1985 | 3880801 |
| increased sensitivity of corynebacterium parvum-treated mice to toxic effects of indomethacin and lipopolysaccharide. | female balb/c and c3h/hej mice develop increased sensitivity to the toxic effects of indomethacin after injection of nonviable corynebacterium parvum. the increased sensitivity developed within 4 days of intraperitoneal injection of the organisms and started to resolve 14 days after injection. the development of increased sensitivity was dependent on the quantity of organisms injected and the concentration of indomethacin utilized. the effect was not observed when c. parvum-treated animals were ... | 1985 | 3881348 |
| adjuvant corynebacterium parvum immunotherapy for squamous cell epitheliomas of the oral cavity, pharynx, and larynx. | patients with primary squamous cell epitheliomas of the oral cavity, pharynx, and larynx were stratified according to stage and site and randomized to receive either intratumoral immunotherapy with corynebacterium parvum followed 2 weeks later by surgery and postoperative c parvum for 2 years or surgery alone. there were 209 patients entered into the trial and 176 were fully evaluable. all prognostic variables were similar between the two groups. there was no difference in disease-free survival ... | 1985 | 3881630 |
| [biochemical changes in the blood of sheep with experimental corynebacterium infection]. | investigations were carried out with 24 sheep divided into two groups of twelve animals. the first group were infected via the lateral recessus of the tarsal joint with 2 cm3 of a 24-hour broth culture of corynebacterium pyogenes, and the second one were infected i/v with 3 cm3 of the same culture. the changes in the total protein, protein fractions, and blood electrolites in the blood were followed up. it was found that the infection of corynebacterium pyogenes affected the total reactivation o ... | 1985 | 3887745 |
| bacterial flora of airline headset devices. | external otitis caused by staphylococcus aureus was observed in two patients after they wore airline headset devices. the bacterial flora of 40 headset devices was evaluated. bacteria were recovered from all headsets, and the number of organisms ranged from 10 to 1,200 (mean 138 +/- 246 organisms per headset). the predominant organisms recovered were s. aureus (in 12 headsets), bacillus sp. and s. epidermidis (ten headsets each), alpha-hemolytic streptococci (in eight) and corynebacterium sp. (i ... | 1985 | 3887959 |
| appearance of immunoglobulin classes and complement (c3) during corynebacterium renale-induced experimental pyelonephritis in the rat. | the local appearance of various immunoglobulin (ig) isotypes in the urinary tract during ascending pyelonephritis was studied in rats experimentally infected with corynebacterium renale. the indirect fluorescent antibody assay was used to detect igg, igm, iga, ige, and c3 on c renale present in the urine of the experimental animals. corynebacterium renale coated with igm and igg antibodies was found beginning on the 4th day after induced infection, with igg being the more abundant isotype. coati ... | 1985 | 3888008 |
| a microaerophilic coccus in pyogenic infections of ruminants. | pyogenic infections of cattle, sheep and goats were examined for the presence of a gram positive bacterium that has been designated "microaerophilic coccus" by other workers. the bacterium was found to be involved in a range of disease processes, including foot and soft tissue abscesses, mastitis, pericarditis and pyometra in cattle, joint and foot abscesses in sheep and foot abscesses in goats. the characteristic feature of the bacterium was its satellitic growth around colonies of other organi ... | 1985 | 3888166 |
| mastitis due to a group of pyogenic bacteria. | | 1985 | 3888167 |
| camp test for presumptive differentiation of corynebacterium renale and other bovine urinary corynebacteria. | | 1985 | 3892125 |
| field studies on linear dodecyl benzene sulfonic acid teat dip. | a teat dip containing 1.94% linear dodecyl benzene sulfonic acid and 12% glycerine, an anionic detergent formulation, was evaluated in two field trials on a commercial dairy. in trial 1, the teat dip was compared to an undipped control in a split-herd design. incidence of infection with streptococcus agalactiae was reduced 57.8%; infections with presumptively identified staphylococcus aureus were not reduced. milking machine function and milking procedures may have affected teat dip effectivenes ... | 1985 | 3894446 |
| comparison of caf versus cmfp in metastatic breast cancer: analysis of prognostic factors. | one hundred fifty-five eligible women with metastatic breast cancer were randomly allocated to receive monthly cycles of either cmfp (cyclophosphamide, methotrexate, 5-fluorouracil, prednisone) or caf (cyclophosphamide, doxorubicin, 5-fluorouracil), and 12 patients were studied to evaluate the effects of additional corynebacterium parvum immunotherapy. overall response rates of 53% were seen with cmfp and caf. caf was associated with significantly more complete responses than cmfp (17% v 5%). ho ... | 1985 | 3894587 |
| quantitative measurements of humoral immune response in mice to a fanft induced bladder tumor. | using unfixed mouse bladder tumor cells (mbt) as target cells and a modified avidin-biotin-complex (abc) method made it possible to detect a humoral immune response in c3h mice with growing mbt tumors. the rise of the serum levels is significant (p less than 0.005) when compared to control animals and correlates with the tumor size. mice with recurrences after surgical removal of the primary tumor had significantly (p less than 0.05) higher serum values than animals without recurrence. purulent ... | 1985 | 3895707 |
| [pharmacokinetics of amoxicillin trihydrate in sheep infected experimentally with corynebacterium pyogenes and escherichia coli]. | a comparative experiment was carried out with sheep that were infected i/v and via the joints with corynebacterium pyogenes and escherichia coli, and with normal sheep left as controls. the pharmacokinetic parameters were determined of amoxicillin-trihydrate following its i/m application to all animals in a 20 percent oil suspension. it was found that there was delayed excretion of the antibiotic, and as a rule it was maintained in higher concentrations in the diseased animals. the differences w ... | 1985 | 3898563 |
| treatment of corynebacterium equi pneumonia of foals: a review. | combined antimicrobial drug treatment was recommended for foals with corynebacterium equi pneumonia. the preferred combination is orally administered erythromycin estolate (25 mg/kg of body weight, qid) plus rifampin (10 mg/kg, bid). erythromycin estolate also can be combined for synergistic effect with sodium benzyl penicillin given iv (100,000 iu/kg, qid) or with ampicillin given iv (11 to 15 mg/kg, qid). a third choice is sodium benzyl penicillin iv with gentamicin im (2.2 mg/kg, tid) or with ... | 1985 | 3902754 |
| effects of corynebacterium bovis infection on susceptibility to major mastitis pathogens. | experimental challenge procedures were used to study infectivity and virulence of corynebacterium bovis. challenge procedures using staphylococcus aureus (newbould 305) and streptococcus agalactiae (mcdonald 44) were used to study effects of corynebacterium bovis infections on superinfection with major pathogens. rate of infection under experimental challenge conditions was significantly greater with corynebacterium bovis than previously observed for staphylococcus aureus or streptococcus agalac ... | 1985 | 3905890 |