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control of corynebacteriophage reproduction by heteroimmune repression.corynebacteriophages beta and gamma are closely related but heteroimmune; hence, gamma reproduces in c7(beta). a series of gamma mutants, designated gamma-bin (beta-inhibited), has been isolated. they reproduce in only 2 to 14% of infected c7(beta) cells, and, as a result, plaque with an efficiency of 10(-4) to 10(-5) on this strain. the proportion of c7(beta) cells in which gamma-bin phage can replicate is increased to 30 to 80% when immunity is lifted by uv induction of c7(beta) or by heat ind ...1978100610
[comparative study of the bactericidal action of the body of ornithodoros papillipes ticks].experiments in vivo have shown that the ticks of ornithodoros papillipes inhibit both gram-positive and gram-negative bacteria. on gram-positive microorganisms most sensitive to bactericidal effect of ticks have turned to be micrococci, staphylococci, streptococci and bacteria of diphtheria, of gram-negative ones--bacillus coli. of gram-positive microorganisms less sensitive were listeria, of gram-negative ones--salmonellae, agents of tularemia and pseudotuberculosis. at the infection with bacte ...1978100756
[minitest for the biodynamic identification of corynebacteria]. 1978100944
prostaglandin synthesis in spleen cell cultures of mice injected with corynebacterium parvum. 1978102430
isolation, structural studies and chemical synthesis of a 'palmitone lipid' from corynebacterium diphtheriae.the isolation of a 'palmitone lipid' from corynebacterium diphtheriae is described. the use of a temporary hydrophobic protecting group allows the obtaining of the lipid in free and pure form. structural studies by chemical degradation and mass spectrometry allow one to propose structure ic for this compound, namely 6-(2-tetradecyl 3-keto octadecanoyl)-alpha-d-trehalose. this structure was confirmed by chemical synthesis.1978102431
[action of corynebacterium parvum on the activity of glycosidases and proteases of peritoneal macrophages in the mice].glycosidase and peptidase of non-treated mouse peritoneal macrophages were characterized. the enzymatic activities of corynebacterium parvum stimulated mouse macrophages were compared to those of macrophages obtained from non-treated animals. all the enzymatic activities, but beta-c-galactosidase, were higher in stimulated mouse macrophages.1978102445
quantitative studies on competitive activities of skin bacteria growing on solid media.earlier quantitative investigations of antagonism between skin bacteria were based on the use of liquid cultures, but a more realistic model has now been devised, based on the use of the surfaces of solid media. pure or mixed inocula were spread evenly over suitable agar media in petri dishes marked out with a standard grid. growth curves were constructed from viable counts of the surface bacteria after they had been removed from excised squares of the agar media and dispersed. the method was hi ...1978102799
[participation of bacterial neuraminidases in the development of disease]. 1978103344
[a leg ulcer from the tropics caused by corynebacterium diphtheriae?]. 1979104183
[use of microbial cells of corynebacterium diphtheriae for preparing a nutrient medium].nutrient media prepared on the basis of microbial cells (corynebacteria diphtheriae) proved to be no less nutrient in comparison with conventional media prepared on the full-value food products. use of diphtheria bacilli (by-products of diphtheria toxoid production) as the basis for nutrient media permitted to use up to 30% less food products for this purpose.1979105520
three variants of corynebacterium diphtheriae subsp. mitis (belfanti) isolated from a throat specimen.three variants of a corynebacterium diphtheriae subsp. mitis strain belfanti, two toxigenic (phage types 7 and 11) and one nontoxigenic (phage type 7), were simultaneously isolated from the throat of an adult.1978106070
[chemotaxonomic markers of several coryneform bacteria and the "rhodochrous" group].chemotaxonomic characters (the monosaccharide composition and diaminopimelic acid (dap) of cell hydrolysates, the type of lipid lcn-a) were studied with bacteria of the "rhodochrous" complex and the arthrobacter genus isolated from natural substrates as well as with collection strains of the genera arthrobacter, brevibacterium and corynebacterium. if arabinose, galactose and meso-dap were present in cell hydrolysates of these bacteria, they always contained lipid lcn-a. bacteria of the "rhodochr ...1978106219
cross-reactions between mycobacteria. ii. crossed immunoelectrophoretic analysis of soluble antigens of bcg and comparison with other mycobacteria.cross-reactions between mycobacterium bovis bcg and various other mycobacteria, nocardia asteroides, corynebacterium pyogenes and listeria monocytogenes were studied by incorporating antibodies against these bacteria in the intermediate gel of a crossed immunoelectrophoretic system with bcg antigen and anti-bcg antibodies. in the bcg reference system forty-four distinct antigenic components were recorded, of which thiryt-three cross-reacted with mycobacterium tuberculosis, twenty-five with m. av ...1979106465
[testing of a system of unidirectional serologic reactions for detection of diphtheria antigens and antibodies]. 1979106599
[heteromorphism of corynebacteria. i. macrocells].a possibility of formation of macrocells (mac) of diphtheria bacilli was expressed to a different degree; the extreme expression are giant and supergiant forms. giant forms with section dimension of 3--5micron retained their capacity to disorderly septation with the resultant formation of microcells (mic). apparently some of the septa were not realized. supergiant forms were revealed as a layer and its transverse section. the length of the latter reached 30micron with the transverse section of 2 ...1978106605
structural determination of 'cord factor' from a corynebacterium diphtheriae strain by a combination of mass spectral ionization methods: field desorption cesium cationization and electron impact mass spectrometry studies.the composition and structure of a preparation of 'cord factor' (di-beta-hydroxy acyl trehaloses) from corynebacterium diphtheriae have been determined by a combination mass spectral ionization methods. the methods were tested by means of synthetic 6,6'-dicorynomycolate of alpha-d-trehalose prior to their use on natural products. the determination of the molecular weight of the components and the estimation of their relative abundance in the natural mixture were made by field desorption mass spe ...1978106902
a comparison of five serological tests for the diagnosis of experimental corynebacterium ovis infection in sheep. 1979106921
ige synthesis in man. ii. comparison of tetanus and diphtheria ige antibody in allergic and nonallergic children. 1979107210
isoprenoid quinones in the classification of coryneform and related bacteria.menaquinones were the only isoprenoid quinones found in 85 of the 95 coryneform bacteria examined. dihydromenaquinones having nine isoprene units were the main components isolated from corynebacterium bovis, from other glutamic acid-producing strains, and from arthrobacter globiformis and related species. dihydromenaquinones with eight isoprene units were found in brevibacterium linens, the remaining corynebacterium species and strains probably belonging to the genus rhodococcus. tetrahydromenaq ...1979107269
non-specific agglutination of corynebacterium ovis by precolostral and young lamb sera.an agglutination reaction, relatively coarse compared to that obtained with immune sera, was observed when corynebacterium ovis cells were incubated with lamb sera collected before and after ingesting colostrum. the reaction did not appear to involve immunoglobulin since it was not affected by treatment of precolostral lamb serum with rivanol, mercaptoethanol or rabbit antisheep serum. igm was detected in only three of 10 precolostral samples with agglutinating activity and immunofluorescence st ...1978107549
bactericidal effects of anesthetics. 1979107831
a modified gel-diffusion technique for testing toxigenicity of corynebacterium diphtheriae. 1978108219
[enzymes of intermediary metabolism in coryneform bacteria].enzymes of the intermediate metabolism were studied in ten strains of corynebacterium-like organisms belonging to the genera arthrobacter, brevibacterium, corynebacterium and nocardia. all of these were found to contain enzymes of the glycolytic pathway, and nine strains among ten had dehydrogenases of the pentose phosphate shunt. the activity of enzymes of the citric acid cycle was low: alpha-ketoglutarate dehydrogenase was not found in arthrobacter, corynebacterium, brevibacterium linens and n ...1979108525
immunodiffusion studies of ribosomes in classification of mycobacteria and related taxa.ribosomal preparations consisting of crude ribosomes (cr), 30s subunits (30s) and 16s core particles (16s) from four strains of the species mycobacterium bovis (bcg), mycobacterium fortuitum, mycobacterium phlei and mycobacterium smegmatis were analyzed by immunodiffusion technique for taxonomical purposes. the ribosomal preparations tested contained several interspecies cross-reacting precipitinogens. the number of precipitinogens demonstrated at the homologous reactions was generally larger th ...1979109401
epidemiologic studies among amerindian populations of amazônia. i. pyoderma: prevalence and associated pathogens.pyoderma was studied among a representative sample of the residents of four remote amerindian villages, amazonas state, brazil, during july-august 1976. the overall prevalence among the 775 inhabitants examined was 11%, with little intervillage variation. when the attack rates for the entire sample population were calculated by 5-year age intervals, the 0- to 4-year-olds had the highest rate, 31%. the highest prevalence, 38%, was found among 3-year-olds. attack rates were not apparently related ...1979110164
increased synthesis of ribonucleotide reductase after deoxyribonucleic acid inhibition in various species of bacteria.the specific activity of ribonucleotide reductase was found to increase significantly after deoxyribonucleic acid inhibition in seven species of bacteria investigated. this group of bacteria includes species with b12-dependent ribonucleotide reductase as well as some with an escherichia coli-type ribonucleotide reductase.1979110794
characterization and identification of 95 diphtheroid (group jk) cultures isolated from clinical specimens.ninety-five cultures of group jk bacteria isolated from clinical specimens were characterized morphologically and biochemically. the microorganisms were isolated primarily from blood cultures. the bacterial cultures produced positive reactions when tested for catalase, tween hydrolysis, and carbohydrate fermentation. glucose and galactose were fermented by more than 90% of the organisms. gas-liquid chromatography of trimethylsilyl derivatives of whole-cell hydrolysates of some of the group jk cu ...1979110826
nuclease enhancement of specific cell agglutination in a serodiagnostic test for neisseria gonorrhoeae.antiserum to a purified type r lipopolysaccharide antigen isolated from neisseria gonorrhoeae was used in a slide agglutination test and compared with conventional carbohydrate utilization and fluorescent antibody tests to confirm the identity of laboratory cultures classified as typical or "atypical" n. gonorrhoeae. cultures of corynebacterium vaginalis, n. meningitidis, n. catarrhalis, n. sicca, and n. lactamicus were also tested in the slide agglutination procedure. the addition of both deoxy ...1979110830
[antibacterial immunity in diphtheria. experimental research].a number of 700 guinea pigs were immunized by parenteral route with non-toxigenic corynebacterium diphtheriae strains, then inoculated with various doses of homologous and heterologous toxigenic c. diphitheriae strains. the results showed that non-toxigenic c. diphtheriae strains confer a certain degree of protection when the challenge is done with homologous toxigenous strains, especially when not more than 500 million germs/ml are used for the challenge dose. this suggests that the carriage of ...1979111333
[heteromorphism of the corynebacteria. iii. d- (dark) and c- (clear) cell types and multiseptate specimens].a population of corynebacterium diphtheriae may consist of cells with accented (osmiophilic) cytoplasm (cells of the "dark" type, or d type) and cells with cytoplasm having no pronounced osmiophilic properties (cells of the "clear" type, or c type). the divergence of the population into cells of the d and c types occurs at the stage of cell division, the original mother cell being able to divide into 2 or more individual cells belonging to different types (elongated multiseptate cells). at the s ...1979111440
[effect of corynebacterium parvum on the glycosidases in guinea pig alveolar macrophages. role of the way of introduction (author's transl)]. 1978111745
occurrence of 3-oxo-acyl groups in the 6,6'-diesters of alpha-d-trehalose. new glycolipids related to cord factor from corynebacterium diphtheriae. 1979111936
[a tropical ulcus cruris caused by corynebacterium diphtheriae?]. 1979112483
[interrelationship of toxin formation with proteolytic enzyme synthesis in the process of cultivating diptheria microorganisms].for the first time the synthesis of proteolytic enzymes by corynebacterium diphtheriae has been shown to precede the process of toxin formation. the process of controlling the proteolytic activity of enzymes seems to be a suitable basis for the evaluation of toxin formation in mathematically planned experiments with strictly controlled tasks.1979112807
immunization against schistosoma mansoni in rhesus monkeys and the requirement of activation of both cell-mediated and humoral mechanisms.when groups of rhesus monkeys were pretreated with bcg plus hyperimmune serum from monkeys with chronic schistosomiasis or with dialyzable transfer factor from uninfected monkeys plus hyperimmune serum and were challenged with 1,500 cercariae of schistosoma mansoni, the mean worm burdens were significantly lower than that of untreated controls. pretreatment with neither bcg alone nor corynebacterium parvum plus a membrane antigen of adult worms of s. mansoni affected susceptibility. neither lymp ...1979113342
[appearance in domestic animals of corynebacterium diphtheriae and other corynebacterium strains pathogenic for man]. 1979113847
activity of penicillin, erythromycin, and cephalosporins against isolates of corynebacterium diphtheriae from cutaneous lesions. 1979114513
isolation of a cured strain from corynebacterium diphtheriae pw8.a nonlysogenic, non-toxinogenic strain was isolated from the pw8 strain of c. diphtheriae by two-step ultraviolet induction. this strain was lysed by phages derived from the pw8 strain but not by beta phages from the c7(beta) strain. when this cured strain was lysogenized with phages from the pw8 strain, toxin production by the resulting lysogens was about a half or a quarter of that of the parent strain pw8.1979115787
characterization of a screening test for diphtherial toxin antigen produced by individual plaques of corynebacteriophages.a passive immune hemolysis assay has been developed to detect diphtherial toxin produced in individual plaques of tox+ corynebacteriophages. this assay permits rapid screening of large numbers of corynebacteriophages for their ability to code for diphtherial toxin or related antigens. the specificity of the assay and its potential usefulness for genetic studies of toxinogenesis have been demonstrated with well-characterized tox+ and tox- laboratory strains of corynebacteriophages.1979115898
[effect of the degree of culture aeration on diphtheria toxin production and growth of 3 variants of corynebacterium diphtheriae pw 8]. 1979116098
corynebacterium equi in the cottontop marmoset (saguinus oedipus): a case report.a wild-caught cottontop marmoset died after a short illness characterized by loss of appetite, loss of weight and general unthriftiness. necropsy revealed a large thoracic abscess from which corynebacterium equi was recovered.1979117222
erythromycin and clindamycin resistance in corynebacterium diphtheriae from skin lesions.erythromycin- and clindamycin-resistant corynebacterium diphtheriae isolates were recovered from skin lesions. resistance to erythromycin and clindamycin was induced by a subinhibitory concentration (0.03 microgram/ml) of erythromycin. clindamycin (0.07 microgram/ml) was a more effective inducer of its own resistance than of erythromycin resistance. erythromycin-inducible cross-resistance to vernamycin b alpha was demonstrated in disk diffusion tests.1979117748
diagnosis of corynebacterium pyogenes infection in pigs by immunodiffusion test with protease antigen.a protease antigen was prepared from the culture supernatant of corynebacterium pyogenes by concentrating with a flash evaporator and ultrafiltration. it was adjusted to the concentration of 32 units by the single radial immunodiffusion with a tentative standard serum. in the immunodiffusion test, the antigen of 4 units reacted enough with sera having an antibody titer ranging from 1 to 128. as a result, it was decided that the antigen of 4 units should be used in the immunodiffusion test for th ...1979118384
non-toxigenic corynebacterium diphtheriae causing subacute bacterial endocarditis: case report.this is the case report of a 13-yr-old european child from a boarding school at herberton, on the atherton tableland, who developed subacute bacterial endocarditis, with 6 blood cultures at different times growing a non-toxigenic strain of corynebacterium diphtheriae.1979118422
effect of metal ions on diphtheria toxin production.the effect of several metal ions on the production of diphtheria toxin was tested. by using the gel immunodiffusion system for detecting toxin, a wide range of metal ion concentrations was conveniently surveyed. five divalent cations, fe2+, cu2+, co2+, ni2+, and mn2+ inhibited toxin production within a range of concentrations that did not inhibit growth of the producing strain. growth and toxin production were inhibited at identical concentrations by both cd2+ and zn2+, whereas al3+ and sr2+ aff ...1979118927
bacteriology of rattlesnake venom and implications for therapy.although the incidence of infection secondary to the bites of venomous snakes remains unknown, the routine use of prophylactic antimicrobial therapy is advocated. in this study, the venom from 15 rattlesnakes was cultured, and 58 aerobic and 28 anaerobic strains of bacteria were isolated. the most common species isolated were pseudomonas aeruginosa, proteus species, coagulase-negative staphylocci, and clostridium species. bacteroides fragilis was also recovered. when the fang sheaths of four add ...1979119002
[carboxylation enzymes of coryneform bacteria].the enzymes of carbon dioxide heterotrophic fixation were studied in six strains of coryneform bacteria belonging to the genera arthrobacter, brevibacterium, corynebacterium and nocardia. all of the strains were found to contain pep (phosphoenolpyruvate) carboxylase (ec 4.1.1.31), nadp or nad dependent malic enzymes (ec 1.1.1.38--40). pyruvate carboxylase (ec 6.4.1.1) was found only in three strains of coryneforms: brevibacterium ammoniagenes, corynebacterium aquaticum and nocardia erythropolis. ...1979119147
studies on the pw 8 phage of the park williams no. 8 strain of c. diphtheriae and on species within corynebacterium genus capable of producing diphtherial toxin. 1978120166
prevalence of corynebacterium diphtheriae in pyoderma and other skin lesions. 1979120849
regulation of chorismate-derived antibiotic production. 1979121030
method for quantitating sensitivity to a staphylococcal bacteriocin.a convenient method for quantitating the sensitivity of large numbers of bacterial strains (presently corynebacterium diphtheriae) to a staphylococcus aureus phage type 71 bacteriocin is described.1979121117
[bacteriological examination of amniotic fluid after intra-amnial tocometry sub partu (author's transl)].two sets of group of 50 women were examined and compared to find out if the introduction of continuous intra-uterine catheter during labour increased infection. amniotic fluid was withdrawn from both groups and examined. also a catheter was introduced into the amniotic sac of one group and after 2 and 5 hours amniotic fluid was also withdrawn from both groups and examined. inhaled amniotic fluid from the infant was also withdrawn and bacteriologically examined both quantitatively and qualitative ...1979121183
differentiation of genera of the coryneform bacteria.a scheme of the generic structure of the group of coryneform bacteria, including the genera arthrobacter, brevibacterium, cellulomonas, corynebacterium, and rhodococcus, is suggested. morphological, chemotaxonomic (presence and stereochemical form of diaminopimelic acid, lipid a, and l-arabinose), and physiological features were used as diagnostic criteria. the position of microbacterum and mycococcus and of coryneforms with a nocardial wall but giving a positive hugh-leifson anaerobic test, and ...1979121544
[septic arthritis due to a nontoxigenic diphtheria bacillus].septic arthritis of the hip in a 2 year old child is described. a nontoxigenic diphtheria bacillus was isolated in large numbers from the articular fluid. the same organism was isolated from excoriated skin lesions of the toes. the bacteriology, epidemiology and pathology of the infection are discussed.1979122141
[the bacterial degradation of steroids in urine]. 1975123677
some disorders of wild deer in the united kingdom. 1975124987
sensitivity of haemophilus vaginalis (corynebacterium vaginale) to oleandomycin and spectinomycin.haemophilus vaginalis is highly sensitive to oleandomycin. the mic ranged from 0.035 to 0.15 mug/ml. the sensitivity of h. vaginalis to spectinomycin was 2.5-5.0 mug/ml. the sensitivity of h. vaginalis to spectinomycin is 3-4 times higher than that of neisseria gonorrhoeae. a favourable effect in the treatment of vaginitis caused by h. vaginalis could thus be expected.1975125402
[effect of a polysan preparation for the treatment of acne on the growth of corynebacterium acnes and staphylococcus pyogenes aureus]. 1975125629
chemical structure of the peptidoglycan, its modifiability and relation to the biological activity.the peptidoglycan is a heteropolymer composed of polysaccharide chains which are cross-linked through short peptides. the polysaccharide moiety (glycan) is made up of beta-1,4 glycosidically linked n-acetylglucosamine and n-acylmuramic acid residues. the carboxyl group of muramic acid is usually substituted by a peptide which consists of alternating l- and d-amino acids. these peptide subunits are cross-linked between the diamino acid in position 3 and the c-terminal d-alanine in position 4 of a ...1975126547
pathogenesis of acne vulgaris. 1975127116
[genetic bases for the selection of microorganisms using analogs].the main mechanisms are considered for biosynthesis processes regulation by means of repression and inhibition with final products. on the basis of these mechanisms the state and prospects of the directed alteration of various stages in regulating the synthesis of primary and secondary metabolites, using breeding selection of mutants resistant to analogues are discussed. the main regularities are presented for using analogues of primary metabolites in the breeding strains with overproduction of ...1975128859
a cytochemical study of the in vitro interaction between normal and activated mouse peritoneal macrophages and tumor cells. 1976129574
[the pathogenesis of acne vulgaris (author's transl)].stickl's method of oral treatment of acne vulgaris with antigens has been carried out on 26 test persons. during the treatment the number of comedones increased significantly and the number of papules decreased significantly. biochemically, a significant increase of the free fatty acids and a significant decrease of the triglycerides could be demonstrated in the skin surface lipids, the total amount remaining unchanged. the following important conclusions for the pathogenesis of acne may be draw ...1976131909
fulminant diphtheritic mitral valve endocarditis.fulminant endocarditis affecting the mitral valve in an 11-year-old boy was caused by a nontoxogenic strain of corynebacterium diphtheriae.1976133640
[studies on ozone therapy of acne vulgaris].ozone therapy using the vapozone 9, an instrument in normal commercial usage, has been carried out on the forehead of 16 male test persons on 7 consecutive days. before the treatment began and at the end of the treatment period the skin surface lipids on the unchanged skin (casual level) and two hours after defatting the skin (replacement sum) were taken by direct extraction and analysed by means of thin layer chromatography. the results of these investigations rule out a decrease in the free fa ...1976134522
topically applied antibiotics in acne vulgaris: clinical response and suppression of corynebacterium acnes in open comedones.topical antibiotics were used on patients with acne vulgaris. corynebacterium acnes organisms from open comedones were quantitated during treatment, and the progress of the disease was evaluated. clindamycin lotion completely suppressed the growth of c acnes organisms, whereas erythromycin and tetracycline did not depress the c acnes counts. taken as a group, these antibiotics gave a substantial improvement of the disease on the treated side as compared with paired untreated sides of the face a ...1976134675
[ultrastructure and microflora in follicles and comedones].the resident flora of skin surface, sebaceous follicles, and acne comedones: pityrosporum, micrococci, and corynebacterium (propionibacterium) acnes is described. the nomenclature, topography, incidence, pathogenic role, and especially the ultrastructural morphology of these organisms are presented.1976136430
amino acid metabolism. 1976137369
predominant cultivable microbiota in periodontosis. 1977138729
acne fulminans: investigation of acute febrile ulcerative acne.eight cases of acne fulminans (acute febrile ulcerative acne) are compared with 13 previously reported cases. this rare disorder of male teenage patients is characterized by the sudden appearance of highly inflammatory, tender, ulcerative and crusted lesions on the back, chest, and face: it is one of the most scarring acute dermatologic disorders of young patients. at the onset of the disease, all patients showed febrile temperatures and marked leukocytosis; other systemic symptoms occurred with ...1977139850
an acne-free naevus.investigation of rare disorders may sometimes help in the understanding of common problems. we describe a patient with an unusual and previously unreported acne-free naevus occurring in an area severely affected by acne. investigation revealed smaller sebaceous glands, a reduced sebum excretion rate, decreased number of corynebacterium acnes in the pilosebaceous ducts and a reduced conversion of testosterone to 5 alphadihydrotestosterone in the areas which were free of acne compared with acne-be ...1977139913
acne vulgaris: an investigation into the number of anaerobic diphtheroids and members of the micrococcaceae in normal and acne skin.a quantitative study was made of the microflora of 174 acne and 68 non-acne subjects. two groups of organisms were investigated, the anaerobic diphtheroids and members of the micrococcaceae. the results showed high numbers of both groups of bacteria in skin bearing blackheads, papules or pustules and in non-acne adolescent skin. there were significantly lower numbers of bacteria in the pilosebaceous ducts of normal looking skin in acne areas and in pre-adolescent skin when compared with non-acne ...1977141301
differential chemical protection of mammalian cells from the exotoxins of corynebacterium diphtheriae and pseudomonas aeruginosa.many drugs or chemicals had markedly different effects on the cytotoxicity induced by pseudomonas aeruginosa exotoxin a (pe) or corynebacterium diphtheriae exotoxin (de). the glycolytic inhibitor naf protected cells from de but potentiated the cytotoxicity of pe. another energy inhibitor, salicylic acid, also protected cells from de but had no effect with pe. colchicine and colcemid did not affect the cytotoxicity of either toxin. cytochalasin b exhibited a modest protection from de but no effec ...1977141424
[species composition of heterotrophic bacteria in the water of the rybinek reservoir].twenty four cultures of heterotrophic bacteria were isolated from the water of the rybinsk reservoir on a medium containing organic matter. bacteria belonging to the families pseudomonadaceae and achromobacteriaceae were most widely distributed; bacteria of the mycobacteriaceae family were encountered less often. predominating species which belonged to the genera pseudomonas, caulobacter, flavobacterium, mycobacterium, and corynebacterium were isolated from the central part of the reservoir. the ...1977142898
[interrelationship between toxigenic and non-toxigenic diphtheria microbes in the epidemic process].a study of the circulation of toxigenic and nontoxigenic diphtheria bacilli was carried out in several carrier state foci under conditions of a natural course of the epidemic process. there were 2623 persons under observation. a total of 32158 analyses were carried out, and 2271 strains were isolated and studied. no formation of the toxigenic variants of diphtheria bacillus as a result of phage conversion was revealed in the foci of carrier state despite the wide spread in them of nontoxigenic l ...1977143172
effect of three nematicides on the growth of some phytopathogenic bacteria and fungi.the effect of three nematicides, aldicarb, fensulfothion, and phenamiphos at four concentrations (1, 5, 25, and 125 ppm) was tested on the growth of five bacteria, agrobacterium tumefaciens, corynebacterium fascians, erwinia carotovora, pseudomonas solanacearum, and streptomyces scabies and four fungi, fusarium oxysporum f. sp. vasinfectum, fusarium solani, rhizoctonia solani, and sclerotium bataticola. of the bacteria, p. solanacearum was most affected by the chemicals at all concentrations, wh ...1977143857
acne vulgaris: recent advances in pathogenesis and treatment.hormonal factors, particularly androgens, appear to be important in the pathogenesis of acne vulgaris. the sebaceous glands in acne are more sensitive to normal blood levels of androgens, and are stimulated to produce more sebum. corynebacterium acnes in the sebaceous follicles act on triglycerides in the sebum to form free fatty acids which might alter the process of keratinization in the follicular canal. a microcomedo is formed which can progress to the clinical lesions of acne. sebum and its ...1977144774
[treatment of inflammatory and proliferative skin diseases].treatment of inflammatory and proliferation dermatoses can now be accomplished with pharmacologic agents which inhibit production of mediators or their actions. the immune system can be stimulated by thymosin, imidazo drugs, bcg, corynebacterium parvum and idoxyuridine. immune complex diseases may be treated with corticosteroids, clofazimine, sulfonamides, antimalarial drugs, and nicotinic acid. low dose, safe immunosuppressive therapy can successfully control scleromyxedema, guttate parapsorias ...1977146028
complement activation by corynebacterium acnes. 1978148901
[effect of corynebacterium parvum on the immune response in guinea pigs. i. mode of enhancement of the anamnestic response and development of delayted hypersensitivity after treatment with corynebacterium parvum].the effect of corynebacterium parvum (c. parvuum) on the immune response of the guinea pig to ovalbumin varies with the protocol of immunization. the marked effect of c. parvum on the anamnestic response in the rabbit has been confirmed in the guinea pig when immunization is carried out intradermally with a mixture of c. parvum and ovalbumin. when c. parvum is given intravenously or subcutaneously or intradermally but separately from the antigen, this effect is not observed. whatever the route o ...1977148948
[effect of corynebacterium parvum on the immune response in guinea pigs. ii. passive transfer of enhanced anamnestic response and delayed hypersensitivity observed after treatment with corynebacterium parvum].after intradermal immunization with a mixture of corynebacterium parvum (c. parvum) and ovalbumin guinea pigs show a markedly increased anamnestic response to an intradermal booster of ovalbumin as compared to controls treated with ovalbumin only. at the same time a reaction of delayed type hypersensitivity is observed in the treated animals, but not in controls. the enhanced anamnestic response as well as the posivitive skin reaction were transferred to strain 2 histocompatible guinea pigs by p ...1977148949
an analysis of conditions allowing corynebacterium parvum to cause either augmentation or inhibition of natural killer cell activity against tumor cells in mice.we have analyzed the impact of in vivo administration of corynebacterium parvum on the mouse immune system against murine tumors, using the natural cytotoxic ability against tumors of normal mouse lymphoid cells as a baseline. a striking difference was found depending on the route of administration. intravenous inoculation of bacteria would result in a significant decrease or sometimes complete abolition of natural cytotoxicity toward tumor cells of the spleen cells of treated mice. on the other ...1978149772
ultrastructural basis for the assay of topical acne treatments. transmission and scanning electron microscopy of untreated comedones.after two decades of using systemic antibiotics as a main treatment for acne, emphasis is again being placed on topical agents. thus, it is highly desirable to have a procedure whereby the activity of the various compounds can be evaluated by direct visualization. scanning electron microscopy combined with transmission electron microscopy provide the tools for such in assay. this study describes the ultrastructure of untreated comedones and provides the baseline or control data necessary for tes ...1978151693
[characteristics of nucleoside and pyrimidine base metabolism in corynebacterium glutamicum].corynebacterium glutamicum atcc 13032 can utilize uridine as a sole source of carbon for its growth. uridine degradation seems to be catalysed by hydrolase since it does not depend on the presence of phosphorus when the enzyme activity is assayed in vitro. other nucleosides (adenosine, inosine, guanosine, cytidine, thymidine, deoxyuridine, deoxyadenosine, deoxyguanosine) cannot serve as a source of carbon for the growth of the bacterium. the label of thymidine-3h (methyl) is not incorporated int ...1978151772
epidemiological features of skin diphtheria infection in rangoon, burma.a survey for skin diphtheria was carried out on 493 patients with skin lesions who were attending veneral diseases & dermatology clinic in rangoon in 1971. 63.8% of the patients had c. diphtheriae in their skin lesions. all ages and both sexes were equally affected. skin lesions yielding c. diphtheriae on culture were indistinguishable from those associated with other bacteria including ecthyma, pyoderma and secondarily infected with parasitic infections. out of 108 strains tested 18.5% were fou ...1978151920
hepatic arterial infusion of corynebacterium parvum and chemotherapy. 1978152477
vancomycin therapy of bacterial endocarditis.fifteen patients with bacterial endocarditis were treated with vancomycin between 1967 and 1976. the indications for vancomycin therapy were penicillin-cephalosporin allergy in six patients, antibiotic resistant bacteria in six, initial therapy in one and culture-negative endocarditis in two. the causative microorganisms were staph. epidermidis (four patients), staph. aureus (two patients), diphtheroids (four patients), viridans streptococci (two patients) and enterococci (one patient). minimum ...1978152580
studies on the interference between the allergic reactions caused by different antigen-antibody systems. 1978152836
studies on the interference between the allergic reactions caused by different antigen-antibody systems.interference between two different in vivo antigen-antibody reactions which occurred simultaneously was studied in guinea pigs. animals were presensitized with an aqueous fraction (cp) extracted from cells of corynebacterium equi, strain ko-85. skin reactions of the arthus type elicited by the cp fraction inhibited passive cutaneous anaphylaxis (pca) induced by bovine serum albumin (bsa) and rabbit anti-bsa serum. pca reactions of the cp-sensitized animals were also inhibited upon simultaneous c ...1979156162
shunt nephritis: demonstration of diphtheroid antigen in glomeruli.a 23-year-old girl with a ventriculo-atrial shunt presented with hematuria, proteinuria and severe oedema. diphtheroid organisms were cultured from blood, cerebrospinal fluid and the shung valve. immunoglobulin, complement components and diphtheroid antigenic material were demonstrated in the glomeruli by immunofluorescence microscopy. treatment of her shunt infection by shunt replacement and antibiotic therapy resulted in slow resolution of her nephritis. the slow resolution of her nephritis su ...1979160200
comparison of natural killer cells induced by kunjin virus and corynebacterium parvum with those occurring naturally in nude mice.natural killer (nk) cells are rapidly elicited in the spleen and peritoneal cavity of mice inoculated intravenously or intraperitoneally with live kunjin virus, and more slowly in the peritoneal cavity of mice inoculated intraperitoneally with formalin-inactivated corynebacterium parvum. nk cells induced by either agent display cytotoxicity for a similar spectrum of syngeneic, allogeneic, and xenogeneic cultured cell lines. by contrast, the cells occurring naturally in the spleen of congenitally ...1979160889
lack of requirement for cell cooperation in the antibody response to dnp conjugated to levan. 1975163703
diphtheria toxin: mode of action and structure. 1975164179
management of sexually transmissible infections during pregnancy. 1975164309
the mode of regulation of bacterial citrate synthase as a taxonomic tool. 1975168310
the action of vibrio cholerae and corynebacterium diphtheriae neuraminidases on the sendai virus receptor of human erythrocytes.studies of the sendai virus haemagglutinin receptor on the human erythrocyte surface have confirmed that it involves 2 leads to 3 linked sialic acid. because the primary specificity of vibrio cholerae neuraminidase is for this linkage, it is able to compete with the virus for the receptor, to which it adsorbs strongly at low temperatures. corynebacterium diphtheriae neuraminidase, whose principal specificity is for a sialic acid linkage other than 2 leads to 3, does not easily remove sendai viru ...1975168311
the mannophosphoinositides of corynebacterium aquaticum.besides the monomannophosphoinositide previously reported in corynebacterium aquaticum small amounts of other, apparently more glycosylated, mannophosphoinositides have been identified in stationary phase cells. moreover, by labelling cells with [32p]pi, phosphatidylinositol was found, comprising about 1.5% of the stationary-phase phospholipids. 2. pulse-chase experiments performed on cells in the late exponential phase of growth further suggested the sequence phosphatidylinositol leads to monom ...1975168883
survival of human enteric and other sewage microorganisms under simulated deep-sea conditions.the survival of pure cultures of escherichia coli, streptococcus faecalis, clostridium perfringens, and vibrio parahaemolyticus under simulated deep-sea conditions of low temperature (4 c), seawater, and hydrostatic pressures ranging from 1 to 1,000 atm was determined over a period exceeding 300 h. the viability of e. coli and total aerobic bacteria in seawater-diluted raw sewage subjected to these deep-sea conditions was also measured. there was a greater survival of both e. coli and s. faecali ...1975169733
studies on rat complement. ii. complement level in experimental tumor in rats.in the course of methylcholanthrene induced carcinogenesis in rats, cia50, c4 and c3 increased as compared with control and correlation of tumor size with increase in cia50, c4 and c3 was observed. in the course of dimethylaminoazobenzen carcinogenesis of rats, complement level and c3 level decreased but in splenectomized rats fed by dimethylaminoazobenzen showed elevated level of complement system. after corynebacterium infection, cia50 and c3 of rats increased. this phenomenon is considered to ...1975170442
suppression of cell-mediated tumour immunity by corynebacterium parvum. 1975170531
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