| [a comparative evaluation of the immunological efficacy of adpt vaccine and adt-m anatoxin in the immunization of children against diphtheria and tetanus]. | comparative study of the immunological effectiveness of adsorbed diphtheria-pertussis-tetanus (dpt) vaccine and adsorbed diphtheria-tetanus toxoid with reduced antigen content (adsorbed dt toxoid r) in the immunization of children, carried out in accordance with the vaccination schedule, was made. immune response to the injection of adsorbed dpt vaccine was higher than after immunization with adsorbed dt toxoid r, as evidenced by antibody titers. it was probably due to differences in the number ... | 1991 | 1950266 |
| studies on the utilization of lactose by corynebacterium glutamicum, bearing the lactose operon of escherichia coli. | the entire escherichia coli lactose operon was inserted into an e. coli/corynebacterium glutamicum shuttle vector and introduced into the gram-positive host organism c. glutamicum r 163. recombinant c. glutamicum strains carrying the lac genes downstream of an efficient promoter displayed rapid growth with lactose as the sole source of carbon. two prerequisites were necessary to obtain good growth of c. glutamicum r 163 on lactose: presence of the lacy gene in addition to lacz and an appropriate ... | 1991 | 1953301 |
| mass spectrometry as a tool for identifying group d2 corynebacteria by their fatty acid profiles. | corynebacterium group d2 (cgd2) are lipophilic antibiotic-multiresistant bacteria involved in some infections of immunocompromised patients. the fatty acid composition and structure of different strains was established by several mass spectrometric methods, particularly negative ion tandem mass spectrometry coupled with capillary gas chromatography. non-hydroxylated fatty acid profiles of three strains of cgd2 (atcc 43042, atcc 43043, atcc 43044) were almost identical and revealed the presence o ... | 1991 | 1955869 |
| genetic and biochemical analysis of the aspartokinase from corynebacterium glutamicum. | the lysc/asd gene cluster of corynebacterium glutamicum atcc 13032 was cloned and sequenced. the lysc locus coding for aspartokinase consists of two in-frame overlapping genes, lysc alpha encoding a protein of 421 amino acids (mr 44,300) and lysc beta encoding a protein of 172 amino acids (mr 18,600). the c. glutamicum aspartokinase was purified and found to contain two proteins of mr 47,000 and mr 18,000. a c. glutamicum mutant expressing a feedback-resistant aspartokinase was shown to be chang ... | 1991 | 1956296 |
| necrosis and sloughing of skin associated with limb cellulitis in four cows and a calf: predisposing causes, treatment and prognosis. | four cows and a calf with non-suppurative limb cellulitis were observed subsequently to suffer skin necrosis and sloughing in the affected limbs, either on or distal to the metacarpus or metatarsus. in comparison with six cows with suppurative corynebacterium pyogenes limb cellulitis, topical therapy or the cases with skin necrosis and sloughing was adequate and the prognosis was good, when compared with the rigorous systemic therapy applied to the cows with suppurative cellulitis, some of which ... | 1991 | 1957470 |
| changes in the bovine udder quarters naturally infected by corynebacterium bovis. | of 272 bovine udder quarters studied for mastitis, 19 of them naturally infected with corynebacterium bovis alone, were compared with 16 others infected by c. bovis together with other bacteria and another 36 non-infected quarters. while there was no significant difference in milk somatic cell counts between the quarters infected by c. bovis alone and those affected by c. bovis together with other bacteria (33.37 +/- 20.28 x 10(3) and 33.86 +/- 23.18 x 10(3)/ml of milk, respectively), there was ... | 1991 | 1959018 |
| tumor necrosis factor and its induction by bacterial endotoxins. | using suitable immunomodulators (corynebacterium parvum vaccine, zymosan or muramyl dipeptide), lipopolysaccharides (lps) from various members of the family enterobacteriaceae (escherichia, salmonella, serratia, shigella) were tested on rabbits in relation to the production of tumor necrosis factor (tnf). tnf was determined by means of the serum titration of l-929 cell cultures in the presence of actinomycin d, this with resulting titres of 3.2 x 10(3) to 5.1 x 10(4) iu tnf/ml. analogous titres ... | 1991 | 1960395 |
| endocarditis due to corynebacterium pseudodiphtheriticum: five case reports, review, and antibiotic susceptibilities of nine strains. | five cases of endocarditis due to corynebacterium pseudodiphtheriticum are described. two patients died, two patients with prosthetic valve endocarditis were successfully treated with antibiotics and valve replacement, and one patient with native valve endocarditis was successfully treated with penicillin alone. we also review 12 previously reported cases of c. pseudodiphtheriticum endocarditis. in vitro susceptibilities to 15 antibiotics were determined for nine isolates. the minimum inhibitory ... | 1991 | 1962103 |
| synthesis of collagenase by the phytopathogenic bacterium corynebacterium rathayii. | the collagenase-producing bacterium tentatively called empedobacter collagenolyticum was recently identified as corynebacterium rathayii. production of collagenase was studied in different media containing peptones or peptides of known sequences. a hexapeptide, pro-ala-gly-pro-pro-gly, is an inducer almost as good as collagen. | 1990 | 1962771 |
| cloning and expression of a pili gene of corynebacterium renale in escherichia coli. | a plasmid gene library of corynebacterium renale piliated strain no. 109p+ was prepared in escherichia coli in order to study the chemical structure of the pili of c. renale. of 3,000 recombinant clones tested, 5 reacted with anti-pili anti-serum. the gene products of these clones reacted with anti-pili monoclonal antibodies 8/4, 5/2 and b20/3 but lacked the reactivity with 13/4. sds-page analysis revealed that the expressed protein had a molecular mass of 48 kilodalton and deletion analysis sho ... | 1990 | 1968989 |
| membrane alteration is necessary but not sufficient for effective glutamate secretion in corynebacterium glutamicum. | we showed recently that secretion of glutamate in biotin-limited cells of corynebacterium glutamicum is mediated by carrier systems in the plasma membrane (c. hoischen and r. krämer, arch. microbiol. 151:342-347, 1989). in view of the generally accepted hypothesis that glutamate efflux is directly caused by alterations of the membrane, it was necessary to examine the kind of correlation between changes in lipid content and composition of the bacterial membrane and glutamate secretion activity. t ... | 1990 | 1971623 |
| antigenic cross-reactivity among isolates of group jk corynebacteria. | using rocket and rocket-line immunoelectrophoresis and immunoblotting it was demonstrated that a group of antibiotic-resistant bacteria, including several authenticated corynebacterium jeikeium strains, shared many cross-reacting antigens. only weak cross-reactivity was demonstrated with representatives of three other skin corynebacteria, c. bovis, c. hofmanii and c. minutissimum or with non-coryneforms. differences within c. jeikeium are sufficient to permit the use of immunoblotting as an epid ... | 1990 | 1976676 |
| routine screening for corynebacterium diphtheriae. | | 1990 | 1978064 |
| aspartokinase genes lysc alpha and lysc beta overlap and are adjacent to the aspartate beta-semialdehyde dehydrogenase gene asd in corynebacterium glutamicum. | a 2.1 kb dna fragment of the recombinant plasmid pcs2, isolated from an aminoethyl cysteine (aec)-resistant and lysine-producing corynebacterium glutamicum mutant strain, and which confers aec resistance and lysine production on the wild-type g. glutamicum atcc 13032 was analysed. dna sequence analysis of this fragment revealed three large open reading frames (orfs). the incomplete orf1 does not contain the 5' end of the coding region. orf2, which uses the same reading frame as orf1, is identica ... | 1990 | 1980002 |
| uptake of glutamate in corynebacterium glutamicum. 1. kinetic properties and regulation by internal ph and potassium. | the active uptake system for glutamate in corynebacterium glutamicum is inducible by growth on glutamate as sole energy and carbon source and is also susceptible to catabolite repression by glucose. the basic level of uptake activity is low in glucose-grown cells (1.5 nmol.mg dry mass-1.min-1), it is intermediate when acetate is the carbon source (3.8 nmol.mg dry mass-1.min-1) and becomes fully induced by glutamate (15 nmol.mg dry mass-1.min-1). in all cases the uptake has, except for different ... | 1990 | 1980106 |
| uptake of glutamate in corynebacterium glutamicum. 2. evidence for a primary active transport system. | the inducible glutamate uptake system in corynebacterium glutamicum (krämer, r., lambert, c., hoischen, c. & ebbighausen, h., preceding paper in this journal) was characterized with respect to its mechanism and energy coupling. all possible secondary active uptake mechanisms can be excluded. glutamate transport is not coupled to the translocation of h+, na+ or k+ ions. although changes in membrane potential and uptake activity cannot completely be separated, no correlation between these two para ... | 1990 | 1980107 |
| instillation of vancomycin into a cerebrospinal fluid reservoir to clear infection: pharmacokinetic considerations. | vancomycin instilled in an ommaya reservoir was used to treat a reservoir-associated infection. vancomycin concentrations in cerebrospinal fluid (csf) were measured, and derivation of pharmacokinetic parameters allowed tailoring of dosing. first-order kinetics were observed. the calculated half-life of 3.52 h was less than reported by others, and the apparent volume of distribution (60 ml) was less than anticipated. the elimination constant was 0.197 h-1. empiric dosing based on schedules sugges ... | 1991 | 1984469 |
| seven-pathogen tricuspid endocarditis in an intravenous drug abuser. pitfalls in laboratory diagnosis. | polymicrobial endocarditis is being reported with increasing frequency in drug abusers. however, the full extent of infection may be unrecognized with routine blood culture techniques because of the overgrowth of more fastidious organisms by other pathogens. this report documents an intravenous drug abuser with the first reported case of tricuspid valve endocarditis involving seven pathogens, discusses pitfalls of routine blood cultures and examines the role of the laboratory in microbiologic di ... | 1991 | 1989813 |
| delayed-onset pseudophakic endophthalmitis. | we reviewed 19 cases of delayed-onset pseudophakic endophthalmitis in which diagnostic cultures were performed at one month or more after cataract extraction with posterior chamber intraocular lens implantation. we isolated four different organisms in these 19 cases: 12 propionibacterium species (63%), three candida parapsilosis (16%), three staphylococcus epidermidis (16%), and one corynebacterium species (5%). because of the unusual delayed-onset features of these cases and the retrospective n ... | 1991 | 1992736 |
| persistent biological reactivity of quartz in the lung: raised protease burden compared with a non-pathogenic mineral dust and microbial particles. | this study assessed the potential harmfulness of particles in the lung by measuring their ability to elicit and maintain an inflammatory response and to damage lung tissue. it compared the inflammogenicity of two nondurable, biological particulates (corynebacterium parvum and zymosan) with a pathogenic mineral dust (quartz) and a nonpathogenic dust (titanium dioxide) by dosing rats via the intratracheal route and measuring the consequent alveolitis. the magnitude and duration of the inflammatory ... | 1991 | 1993161 |
| evaluation of api coryne in comparison with conventional methods for identifying coryneform bacteria. | a study was performed to evaluate a new manual miniaturized system, api coryne (api-biomérieux, inc., la balme les grottes, france), in which conventional biochemical methods were used to identify 240 isolates of coryneform and related bacteria. a total of 40% of the isolates were excluded from the study because they could not be identified by conventional methods. identifications of the 240 isolates obtained with api coryne showed a 97.6% concordance with conventional methods (79% after 24 h of ... | 1991 | 1993764 |
| radiological case of the month. cavitary pneumonia due to arcanobacterium hemolytic. | | 1991 | 1994689 |
| augmented production of granulocyte-macrophage colony-stimulating factor and alpha/beta interferon in mice inoculated with heat-killed corynebacterium liquefaciens. | we demonstrated that heat-killed corynebacterium liquefaciens bacteria, as a known potent host immune activity modulator, stimulate spleen cells to produce granulocyte-macrophage (gm) colony-stimulating factor (csf) and another csf with similar activity, as well as alpha/beta interferon, when injected intravenously into mice. alpha/beta interferon was shown to be produced by c. liquefaciens-activated plastic-g-10 column-adherent cells (a cells) in a thymus-independent manner. in contrast, augmen ... | 1991 | 1997406 |
| immunogenicity of haemophilus influenzae type b conjugate vaccines in infant rhesus monkeys. | two haemophilus influenzae type b (hib) polysaccharide-protein conjugate vaccines were evaluated for immunogenicity in eliciting anti-polyribosyl ribitol phosphate (prp) antibodies in infant rhesus monkeys. animals received intramuscular injections of either hib polysaccharide (prp)-meningococcal outer membrane protein complex or hib oligosaccharide-crm197 (hboc) conjugate vaccines on d 0, 28, and 56. because hboc contains the crm197 mutant diphtheria toxin from corynebacterium diphtheriae as it ... | 1991 | 2000253 |
| grouping of some clinically relevant gram-positive rods by automated fatty acid analysis. diagnostic implications. | one hundred and ninety-four strains of aerobically growing gram-positive rods of the genera corynebacterium, actinomyces, arcanobacterium, erysipelothrix, listeria, oerskovia, nocardia, rhodococcus, and of unnamed center for disease control (cdc) groups were checked for cellular fatty acid profiles with the microbial identification system (microbial id, newark, del., usa). in order to obtain unified data usable for the clinical laboratory, 24 or 48 h sheep blood agar cultures were used. it was t ... | 1991 | 2001281 |
| endocarditis caused by corynebacterium group d2. | | 1991 | 2002238 |
| restoration of prostaglandin releasing macrophage populations in lethally irradiated mice with spleen cells from bone marrow-depleted donors. | previous studies in mice severely depleted of bone marrow cells by 89sr showed persistent monocytopenia and impaired expression of prostaglandin e2-releasing splenic macrophages (pgsm) despite the occurrence in the spleen of more than 10-fold increases in pluripotential stem cells and m phi colony-forming cells. to determine whether the observed deficits were due to a lack of precursors of blood monocytes and pgsm in the spleens of 89sr-treated mice, radiation chimeras were established by i.v. i ... | 1991 | 2002284 |
| effect of damage to the teat end on the experimental induction of mastitis in dry cows with corynebacterium pyogenes. | the teat ends of 12 dry cows were contaminated with corynebacterium pyogenes. to determine whether a pre-existing (an)aerobic bacterial infection of the udder was a predisposing factor for a c pyogenes mastitis they included infected and uninfected quarters. anaerobic bacteria could not be found and mastitis was not induced. when the teats were contaminated with c pyogenes after the teat ends had been injured 30 of the quarters became infected, and anaerobic bacteria were demonstrated in many qu ... | 1991 | 2003353 |
| na(+)-dependent succinate uptake in corynebacterium glutamicum. | succinate is effectively taken up by washed cells of corynebacterium glutamicum. the apparent km value of uptake is about 150 microm and the vmax 4-7 nmol (mg dry weight)-1 min-1 and uptake can be competetively inhibited by fumarate and oxaloacetate. the activation energy was determined to be 50 kj/mol. the transport activity is clearly dependent on the presence of na+ ions in the incubation medium and on the membrane potential and has a ph optimum around 8.5. it is concluded that succinate is t ... | 1991 | 2004698 |
| epizootic of external and internal abscesses in a large goat herd over a 16-year period. | from 1973 through 1988, 518 external and internal abscesses were diagnosed in a large commercial goat herd. of the 518 abscesses, 238 were primary and 280 were secondary abscesses in the same or other anatomic locations. during this period, the herd varied in size from 94 goats in 1973 to 431 goats in 1988. abscesses in the jaw area were detected in 141 goats, 4 of which developed osteomyelitis of the mandible. sternal abscesses were detected in 72 goats, with 2 also having osteomyelitis of the ... | 1991 | 2004986 |
| endotoxin-induced cytokine gene expression in vivo. iii. il-6 mrna and serum protein expression and the in vivo hematologic effects of il-6. | endotoxin (lps) at sublethal doses injected i.v. into rats was found to induce il-6 mrna expression peaking at 1 to 2 h in whole organ rna preparations of the spleen, liver, lung, bowel, and kidney. il-6 serum protein levels also peaked at 2 h. tnf and il-1, generally considered to be among the most rapidly released cytokines, also induced il-6 expression. il-6 in turn inhibited tnf and il-1 expression, suggesting that il-6 may be part of a negative feedback mechanism in the cytokine cascade. de ... | 1991 | 2005401 |
| is the incidence of trichomycosis of genital hair underestimated? | | 1991 | 2007685 |
| osteomyelitis due to corynebacterium group d2. | | 1991 | 2009880 |
| tracheobronchitis due to corynebacterium pseudodiphtheriticum. | we have presented a case of tracheobronchitis due to c pseudodiphtheriticum in a patient with copd who was treated with prednisone and apparently was not otherwise immunocompromised. chronic lung disease seems to predispose to infection with c pseudodiphtheriticum; it can also occur in the immunocompetent host. this organism, when isolated in pure culture, should not be dismissed as a contaminant, but must be considered a possible etiologic agent. sensitivity of diphtheroids to antibiotics is ex ... | 1991 | 2014440 |
| necrotizing tracheitis caused by corynebacterium pseudodiphtheriticum: unique case and review. | the occasional pathogenicity of nondiphtheria corynebacteria in both immunocompetent and immunocompromised individuals is now well established. previously described sites of infection include heart valves, wounds, urinary tract, and lungs. this report of necrotizing tracheitis caused by corynebacterium pseudodiphtheriticum illustrates the widening spectrum of infections caused by these organisms. a 54-year-old man developed respiratory distress and symptoms of upper airway obstruction unresponsi ... | 1991 | 2017636 |
| diagnosis of caseous lymphadenitis in goats. | | 1991 | 2017855 |
| lid flora in blepharitis. | the microbiologic evaluations of 332 consecutive patients with the primary diagnosis of chronic blepharitis were reviewed and compared to those of 160 control patients. the most commonly isolated organisms from lids with blepharitis were staphylococcus epidermidis (95.8%), propronibacterium acnes (92.8%), corynebacterium sp. (76.8%), acinetobacter sp. (11.4%), and staphylococcus aureus (10.5%). compared to controls, s. epidermidis (p less than 0.01), p. acnes (p less than 0.02), and corynebacter ... | 1991 | 2019106 |
| corynebacterium striatus keratitis. | we report a case of diphtheroid keratitis that occurred in a compromised cornea. corneal cultures yielded heavy growth of corynebacterium striatus on blood and chocolate agar. the infection responded slowly to treatment with topical fortified cefazolin and fortified tobramycin. this case demonstrates that diphtheroids are capable of causing ocular infections and should not routinely be dismissed as contaminants or commensals. | 1991 | 2019113 |
| hyperammonemic encephalopathy secondary to diphtheroid urinary tract infection in a patient with prune belly syndrome. | | 1991 | 2019147 |
| a sensitive method for isolating fusobacterium necrophorum from faeces. | the isolation of fusobacterium necrophorum present in small numbers in heavily contaminated material such as faeces or soil is hampered by the lack of an efficient selective medium and by the high minimum infective dose of the organism. a sensitive method for the detection and isolation of faecal strains of f. necrophorum type a was based on the subcutaneous injection of faeces, suspended (5% w/v) in broth culture of actinomyces (corynebacterium) pyogenes or staphylococcus aureus to increase fus ... | 1991 | 2019300 |
| [infections caused by non-diphtheroid corynebacteria]. | | 1991 | 2020334 |
| aerobic bacteria from nasal discharge of goats suffering from clinical ppr: isolation and identification. | bacteriological isolation of aerobic bacteria from nasal discharge of achondroplastic west african dwarf goats showing clinical signs of peste des petits ruminants (ppr), and the laboratory procedures carried out for the identification of the isolates are described. from a total of forty nasal swabs obtained seventy five isolates were recovered. the percentage frequency of isolation of different organisms in descending order of occurrence is as follows: staphylococcus 44.0%; streptococcus 22.67% ... | 1991 | 2023545 |
| applications of gas chromatography-mass spectrometry in the study of androgen and odorous 16-androstene metabolism by human axillary bacteria. | the known involvement of axillary microflora with under-arm odour (uao) production led us to determine whether the odorous 16-androstene steroids are formed in the axilla by bacterial metabolism of an odourless precursor such as testosterone. axillary bacteria from 34 men were selectively cultured for aerobic coryneform bacteria (acb), micrococcaceae and propionibacteria. overnight suspensions of bacteria were incubated separately at 37 degrees c for two weeks with radiolabelled testosterone plu ... | 1991 | 2026727 |
| vancomycin-resistant corynebacterium species causing prosthetic valve endocarditis successfully treated with imipenem and ciprofloxacin. | endocarditis caused by a corynebacterium sp. resistant to vancomycin, penicillin g, erythromycin, gentamicin and rifampicin arose in a 44-year-old woman 4 months after replacement of the mitral valve with a prosthesis. she was successfully treated with a 79-day course of intravenous imipenem and ciprofloxacin and replacement of the prosthesis 48 days after treatment began. | 1991 | 2026890 |
| diptheroids and associated infections as a cause of failed instrument stabilization procedures in the lumbar spine. | between february 1985 and october 1987, the authors identified seven patients with occult lumbar spine infections associated with the presence of spinal fixation hardware. six of these infections were with organisms of low virulence; four of the seven patients had polymicrobial infections. all of the polymicrobial infections contained a diptheroid as one of the isolates. two of the seven patients studied had normal sedimentation rates. all had white blood cell counts less than 12,000 cells. imag ... | 1991 | 2028309 |
| experimental corynebacterium pseudotuberculosis infection in lambs: kinetics of bacterial dissemination and inflammation. | infection and pyogranulomas induced by corynebacterium pseudotuberculosis were experimentally reproduced in lambs. in two separate experiments, bacterial multiplication and dissemination were studied in 30 male lambs inoculated subcutaneously into the right ear with 1.1 or 1.5 x 10(8) viable c. pseudotuberculosis strain 19r. infected lambs were necropsied at various times until the 28th day following inoculation. after a transient hyperthermia and a strong local inflammatory reaction, an abscess ... | 1991 | 2031305 |
| identification of plasmid partition function in coryneform bacteria. | we have identified and characterized a partition function that is required for stable maintenance of plasmids in the coryneform bacteria brevibacterium flavum mj233 and corynebacterium glutamicum atcc 31831. this function is localized to a hindiii-nspv fragment (673 bp) adjacent to the replication region of the plasmid, named pby503, from brevibacterium stationis ifo 12144. the function was independent of copy number control and was not associated directly with plasmid replication functions. thi ... | 1991 | 2039232 |
| bacteremia due to corynebacterium jeikeium in a patient with aids. | | 1991 | 2041970 |
| arcanobacterium hemolyticum infection: confused with scarlet fever and diphtheria. | arcanobacterium hemolyticum infections are a common cause of pharyngitis and rash in the 10- to 30-year-old age group. despite its prevalence, many emergency and primary care physicians may not be aware of the pathogenic potential of this organism. we present a case that illustrates the distinctive clinical spectrum of a. hemolyticum infections that may be confused with drug allergy, group a streptococcal scarlet fever, diphtheria, and even toxic shock syndrome. recognition of this syndrome will ... | 1991 | 2045646 |
| corynebacterium parvum versus bacille calmette-guérin adjuvant immunotherapy of stage ii malignant melanoma. | two separate studies have been reported comparing corynebacterium parvum and bacille calmette-guérin (bcg) as adjuvant immunotherapy for stage ii melanoma patients (the milton s. hershey medical center, 48 patients; southeastern cancer study group [secsg], 162 patients). as the criteria for patient selection and drugs used were similar, we have pooled the data to analyze the effects of these two treatments. both studies used bcg (tice, chicago, il) 3 x 10(8) live organisms per treatment by tine ... | 1991 | 2045856 |
| ruffle formation in the evaluation of stimulatory state of hepatic macrophages in rats. | morphological changes in hepatic macrophages after stimulation were observed with a transmission electron microscope in rats. in the normal liver ruffle formation occupied less than 30% of the cell surface facing the sinusoidal space in 21 of 25 macrophages. when the rats received a dose of carbon tetrachloride, hepatic macrophages 1 day later showed ruffle formation to the same extent as in normal rats. in contrast, in rats 6 days after a dose of corynebacterium parvum, ruffle formation was int ... | 1991 | 2051902 |
| mr imaging in an experimental model of brain tumor immunotherapy. | a murine model of implanted cns neoplasia was used to study a new form of brain tumor immunotherapy with intralesional corynebacterium parvum (c. parvum). assessment of treatment protocols has been limited by the inability to assess, noninvasively, tumor burden and/or the inflammatory reaction induced in the murine brain by treatment with c. parvum. this study demonstrates that contrast-enhanced mr imaging can monitor in vivo tumor burden and the immune response to intracerebral c. parvum. kht m ... | 1991 | 2058511 |
| cutaneous botryomycosis. | we report four cases of cutaneous botryomycosis. the predisposing factors included alcoholism, diabetes, and trauma. clinically, the patients had nodules, suppurative plaques, or ulcers. in two cases, staphylococcus aureus was cultured. in one case neisseria species was cultured and in another a coagulase-negative staphylococcus and corynebacterium species were the only organism cultured. all patients responded to systemic antibiotic therapy. | 1991 | 2061434 |
| corynebacterium pseudotuberculosis: in vitro susceptibility to 39 antimicrobial agents. | the minimal inhibitory concentrations of 39 antimicrobial agents for 54 isolates of corynebacterium pseudotuberculosis in vitro have been determined. the most active agents were penicillins, macrolides, tetracyclines, cephalosporins, lincomycin, chloramphenicol, and rifampicin. most isolates were resistant to aminoglycosides, nitrofurans, polymyxins, nalidixic acid, and cycloheximide. | 1991 | 2063546 |
| palpable purpura associated with corynebacterium jeikeium endocarditis. | | 1991 | 2064416 |
| in-vitro and in-vivo studies of human axillary odour and the cutaneous microflora. | the axillary microflora of 34 male subjects were studied in relation to their underarm odour intensity. the predominant groups of micro-organisms were aerobic coryneforms, micrococcaceae and propionibacteria. there was no competition for habitat between these groups (fisher's exact test p greater than 0.05). there was an association between the population density of aerobic coryneforms and the intensity of odour (spearman, p = 0.001). dominance of aerobic coryneforms within the axillary microflo ... | 1991 | 2064946 |
| nzb serum factor (nzb-sf): b precursor cell maturation factor identified in murine lupus. i. identification of 60-kda glycoprotein as the major component from both spleen cell supernatant and serum. | nzb serum factor (nzb-sf), initially identified in sera of very young nzb mice, can enhance maturation and proliferation of sig- pre-b cells in marrow. in the present study, spleen cell supernatant from young nzb mice was used as a source of nzb-sf. nzb mice were treated with corynebacterium parvum 2 weeks prior to sacrifice, and harvested spleen cells obtained at sacrifice were cultured for 24 hr in serum-free medium. one liter of spleen cell supernatant prepared in this way contained nzb-sf-li ... | 1991 | 2065358 |
| pneumonia caused by corynebacterium pseudodiphtheriticum. | | 1991 | 2067374 |
| the effect of antibody to caseous lymphadenitis in ewes on the efficacy of vaccination in lambs. | the effect of maternal antibody to the toxin of corynebacterium pseudotuberculosis, produced by caseous lymphadenitis (cla) in ewes or by vaccinating ewes before lambing, on the efficacy of vaccination against cla in their lambs was examined. lambs were allocated to treatments according to either the vaccination history of their dam or level of cla toxin antibody of their dam. they were vaccinated twice using 2 different inoculation regimes and then artificially infected with cla organisms. the ... | 1991 | 2069543 |
| changes in the spectrum of organisms causing bacteremia and fungemia in immunocompromised patients due to venous access devices. | a significant increase in the use of vascular access devices has changed the spectrum of organisms causing bacteremia and fungemia at memorial sloan-kettering cancer center. this paper documents the 1988 laboratory experience with bacteremia and fungemia and contrasts some of that data with information obtained in 1984. in 1988, 439 tunnelled-catheters and 355 ports were inserted in patients; 2,778 organisms were subsequently recovered from 933 episodes of bacteremia and fungemia. fifty-percent ... | 1990 | 2073897 |
| in vitro susceptibility of corynebacterium group d2 and corynebacterium jeikeium to twelve antibiotics. | the in vitro susceptibility of 83 corynebacterium group d2 strains and 44 corynebacterium jeikeium strains to 12 antimicrobial agents was determined by an agar dilution technique using mueller-hinton agar supplemented with tween 80 (0.025%). all strains of corynebacterium group d2 were highly sensitive to fusidic acid, pristinamycin, teicoplanin and vancomycin (geometric mean mics 0.047, 0.048, 0.338 and 0.396 mg/l respectively). most of the strains were resistant to other antibiotics tested (ci ... | 1990 | 2073900 |
| native valve endocarditis due to corynebacterium group jk. | we report a case of a 32-yr-old woman on chronic intermittent haemodialysis, who developed endocarditis due to a corynebacterium group jk, involving both the native aortic and mitral valves. despite a four-week treatment with vancomycin, an aortic root abscess developed. the diagnosis was confirmed on autopsy. | 1990 | 2074917 |
| molecular cloning of aldolases for synthetic applications. | | 1990 | 2076016 |
| [the status of antidiphtheria immunity and of the toxigenic corynebacterium diphtheriae carrier state in organized collectives of adults]. | | 1990 | 2077715 |
| the sore throat. when to investigate and when to prescribe. | sore throats are most commonly due to infections, many of which are viral and do not require specific treatment. symptoms and signs of the common cold, influenza or croup, the occurrence of conjunctivitis in some adenoviral infections, generalised lymphadenopathy and splenomegaly in glandular fever or the presence of vesicles characteristic of herpangina (coxsackie a virus) or of herpes simplex infection, occasionally enable a clinical diagnosis and avoid the need for antibiotic therapy. in the ... | 1990 | 2079000 |
| [corynebacterium suis infections in swine. 2. morphological findings in the urinary tract with special reference to the bladder]. | morphological investigations of the urethra, urinary bladder (2 localizations), ureter, renal pelvis and kidneys were performed in sows with corynebacterium suis infection. the first stages of the disease were characterized by changes of the transitional epithelium in the bladder where epithelial vacuolisation, goblet cell differentiation, leucocytic infiltrations, and haemorrhages occurred. in chronically affected animals different stages of a mucopurulent, partly erosive to ulcerative cystitis ... | 1990 | 2080504 |
| nucleotide sequence and organization of the upstream region of the corynebacterium glutamicum lysa gene. | maximum expression of the corynebacterium glutamicum lysa gene is dependent upon the presence of a 2.3 kb region immediately 5' of the lysa reading frame. subcloning and functional analysis of the upstream region implied that this region contained the lysa promoter. sequence determination of the upstream region revealed a single open reading frame, orfx, in the same orientation as lysa. the orfx coding sequence exhibited all the sequence characteristics of a gene with the potential for a 550-ami ... | 1990 | 2082143 |
| phallus-inflammation of ganders: clinical observations and comparative bacteriological examinations of healthy and altered organs. | the examination of acute or chronically altered phallus-tissues of ganders revealed microorganisms belonging to the genera mycoplasma, bacteroides, clostridium, streptococcus, micrococcus, staphylococcus, lactobacillus, corynebacterium, escherichia, campylobacter, proteus, pseudomonas and candida and to the family pasteurellaceae, isolated in different frequencies. bacteriologic examinations of the phallus-tissues and cloacal mucous membranes of healthy juvenile ganders showed microorganisms of ... | 1990 | 2082630 |
| taxonomic implications of the chemical analysis of the d2 group of corynebacteria. | whole cell acid methanolysates from corynebacteria of the d2 group were found to contain meso-diaminopimelic acid, arabinose and galactose. among lipids of taxonomic value, saturated and unsaturated straight chain fatty acids (14 to 18 carbon atoms), tuberculostearic acid (10-methyl octadecanoic acid) and mycolic acids were present. the last compounds ranged from 26 to 36 carbon atoms, the predominant types being 28.2, 28.1, 30.3, 30.2, 32.3 and 32.2. by reverse phase thin-layer chromatography t ... | 1990 | 2083845 |
| [milk chloride level as an indicator of bovine mastitis]. | the aim of this study was to determine an influence of udder infection on milk chloride level and on milk productivity of cows of black and white race. bacteriological analysis was performed by bacterial isolation from milk collected in sterile conditions from single lobes of mammary gland. the study was aimed to detect the following bacteria: streptococcus agalactiae, streptococcus uberis, streptococcus agalactiae, staphylococcus aureus, staphylococcus epidermidis, actinomyces pyogenes, enterob ... | 1990 | 2084451 |
| [classical pseudomembranous diphtheria caused by corynebacterium ulcerans]. | in a 63-year-old patient presenting with signs of classical diphtheria including membranous pharyngotracheobronchitis and myocarditis, corynebacterium ulcerans was isolated in pure culture from the membranes. the strain produced a toxin specific for c. ulcerans but no diphtheria toxin. the patient was discharged after a complicated hospital course including respiratory and cardiac failure. besides corynebacterium diphtheriae, which has very rarely been isolated in switzerland in recent years, co ... | 1990 | 2084836 |
| antimicrobial activity and beta-lactamase stability of bmy-28232, parent compound of an oral cephalosporin. | bmy-28232, an aminothiazolyl imino methoxy cephalosporin which is available as an orally absorbed acetoxyethyl ester, inhibited strains of methicillin-susceptible staphylococcus aureus, hemolytic streptococci, streptococcus pneumoniae, escherichia coli, klebsiella species, and many strains of proteus and providencia stuartii at concentrations less than 1 microgram/ml, including isolates resistant to cephalexin and cefaclor. it had activity similar to that of cefixime, but was more active against ... | 1990 | 2086221 |
| [detection of causative bacteria for bovine mastitis and their susceptibility to beta-lactam antibacterial agents]. | during the period from november 1988 to may 1989, causative bacteria in a total of 172 clinical mastitis cases observed in 66 farms in 5 districts with 6 areas in japan were examined and frequencies of their occurrences were determined. susceptibilities (in mics) of the isolates to 6 beta-lactam antibacterial agents were also determined. as a result, coagulase-negative staphylococci (cns) was identified in 94 out of 172 cases (54.7%) and were the most prevalent. corynebacterium spp., gram-negati ... | 1990 | 2086812 |
| nonspecific stimulation of host defense by corynebacterium kutscheri. ii. isolation of the active moiety. | the isolation and determination of biological activities of the active component of corynebacterium kutscheri were attempted in the present investigation. the antitumor effect was confined to the subcellular particle fraction of this bacterium and was associated with a molecule of glycoprotein nature (40,000-38,000 daltons) isolated from this fraction by affinity chromatography with concanavalin a-sepharose 4b. this substance exerted mitogenic activity on c3h/hej splenocytes and t cells, stimula ... | 1990 | 2087246 |
| the bacteriology of brain abscess: a local experience in malaysia. | 31 cases of intracranial abscess seen over a period of 10 years showed a peak incidence in the second and third decades of life with a male preponderance. tetralogy of fallot and other congenital cyanotic heart diseases were the predominant associated factors (32%). the commonest site of infection was the frontal lobe. gram-stained smears of pus proved to be extremely useful. the majority of the organisms (82%) were either microaerophilic or anaerobic bacteria with streptococcus milleri being th ... | 1990 | 2091359 |
| [inhibition of growth and metastases of lung carcinoma in c57bl/6 mice by corynebacterium parvum and its antitumor mechanism]. | cocrynebacterium parvum (cp) was injected around the tumor and tumor cells were inoculated subcutaneously with activated peritoneal macrophages. the effects on the growth and metastases of lewis lung carcinoma in c57bl/6 mice were observed. experimental results indicated that cp had significant inhibitory effect on the tumor growth and lung metastases. the cytotoxic effects of activated peritoneal macrophages in mice on target tumor cells (l5178y) in vitro were studied with the technique of 3h-t ... | 1990 | 2093073 |
| assessment of a contact-plate sampling technique and subsequent quantitative bacterial studies in atopic dermatitis. | the aerobic bacterial flora of 20 patients with atopic dermatitis and 19 control subjects was extensively sampled using the williamson and kligman scrub technique and a contact-plate method (cysteine lactose electrolyte deficient media). comparison of the two quantitative techniques showed that the contact plate is a reliable and convenient alternative to the scrub technique for the quantification of staphylococcus aureus, micrococci and coagulase negative staphylococci. quantification of bacter ... | 1990 | 2095181 |
| low level toxicity and antitumor activity of butyric mono- and polyester monosaccharide derivates in mice. | this study compares the antitumor activity of five mono- and polyesters of n-butyric acid derived from monosaccharides in the murine model of crocker 180 tg sarcoma. tumor incidence at ten days, mean survival time and final survival rate were significantly affected in all cases. combined treatment by butyric esters, alpha/beta interferon (ifn) and/or corynebacterium parvum used as immunestimulator improved the antitumor protection. studies of acute toxicity in mice, performed by i.p. and oral ro ... | 1990 | 2096598 |
| [corynebacterium jeikeium]. | | 1990 | 2098141 |
| [corynebacterium jeikeium septicemia]. | an adult male with non-hodgkin lymphoma, who had been admitted to the hospital for more than one month and had received previous antibiotic therapy, developed corynebacterium jeikeium septicemia. the organism was isolated in four blood cultures and it was multirresistant, being only sensitive to vancomycin, ciprofloxacin, norfloxacin and rifampin. the patient improved clinically and was bacteriologically cured with intravenous vancomycin therapy. | 1990 | 2098146 |
| penetration of dentine by three oral bacteria in vitro and their associated cytotoxicity. | three common oral bacteria, namely streptococcus sanguis, actinomyces viscosus and corynebacterium spp. were studied with regard to their ability to penetrate etched and unetched dentine and for their effect on underlying cell cultures. the test organisms were grown in cylinders above dentine slices 100 and 500 microns thick for 72 hours. the slices were in contact with tissue culture medium covering a layer of fibroblasts. penetration of 100 microns slices was most rapid with s. sanguis, follow ... | 1990 | 2098336 |
| survey of actinobacillus (haemophilus) pleuropneumoniae infection in swine by different methods. | lung and serum samples from pigs that died or were emergency-slaughtered in a pooled, conventional fattening herd were examined to survey actinobacillus pleuro-pneumoniae infection and to compare the sensitivity of different testing methods. a total of 110 lungs were used for cultural isolation of the agent and direct immunofluorescence (if) of impression smears. boiled lung suspensions were tested by coagglutination (co-a) and agar gel precipitation (agp). eighty-seven sera were tested along wi ... | 1990 | 2099609 |
| penicillin tolerance in arcanobacterium haemolyticum. | it was previously found that arcanobacterium haemolyticum, which can cause tonsillitis with exanthema, is not eradicated from the pharynx by administration of phenoxymethylpenicillin, despite minimum inhibitory concentration values of 0.015-1.0 micrograms/ml. therefore, recent clinical isolates were studied for penicillin tolerance by using a disk diffusion screening test and a pour plate assay. macrobroth dilution minimum inhibitory and bactericidal concentrations and antibiotic kill kinetics w ... | 1990 | 2105360 |
| a pyrolysis-mass spectrometry study of corynebacterium spp. | clinical (66) and collection (38) strains of corynebacterium spp., including c. jeikeium and cdc group d2, and of listeria monocytogenes were examined. conventional characters used in species identification were assessed by a microbiochemical method, and pyrolysis-mass spectrometry (py-ms) was performed with a horizon instruments pyms 200x. classification based on py-ms data yielded clusters that corresponded with species identification and classification groups from conventional data. one small ... | 1990 | 2106034 |
| localization of an origin of replication in corynebacterium diphtheriae broad host range plasmid png2 that also functions in escherichia coli. | subcloning and protoplast transformation studies identified a 2.6 kb fragment of corynebacterium diphtheriae plasmid png2 which contains an origin of replication (orir). molecular combination of the 2.6 kb orir cartridge with escherichia coli plasmid puc18cmr enabled the e. coli cloning vector to replicate within several species of corynebacterium host cells. a 2.6 kb plasmid formed from the orir cartridge alone is capable of replicating in e. coli. this suggests that a single origin could be us ... | 1990 | 2108894 |
| interspecies electro-transformation in corynebacteria. | plasmid dna was efficiently electro-transformed into intact cells of nine corynebacteria strains belonging to brevibacterium lactofermentum, brevibacterium flavum, corynebacterium glutamicum and corynebacterium melassecola. relationships were explored between transformation efficiency and parameters such as electric field strength and pulse length, dna concentration, physiological state and concentration of the cells. in optimal conditions, more than 10(7) transformants per microgram of dna coul ... | 1990 | 2108897 |
| dna sequence homology between attb-related sites of corynebacterium diphtheriae, corynebacterium ulcerans, corynebacterium glutamicum, and the attp site of gamma-corynephage. | chromosomal restriction fragments of corynebacterium ulcerans and c. diphtheriae, containing an integration site for corynephages of the beta family, show homology on southern blots. homologous dna in also found in the soil isolate c. glutamicum, although this strain is not susceptible to beta-corynephages. three of these dna fragments, one for each bacterial strain, and a fragment of gamma-corynephage dna previously shown to contain the phage integration site, were cloned and sequenced. alignme ... | 1990 | 2108899 |
| ph regulation of urease levels in streptococcus salivarius. | potential mechanisms for regulation of urease levels in streptococcus salivarius were examined, including: induction by urea, nitrogen or carbon source repression, and effects of ph and co2 (because co2 enrichment enhanced urease detection on urea agar plates). regulation by either ph or co2 was confirmed by comparison of the urease accumulation pattern during anaerobic growth under co2 with that under n2. under co2, there was an initial buffering plateau at ph 6.2 and a rate of streptococcus sa ... | 1990 | 2110582 |
| nucleotide sequence of the erythromycin resistance gene from the corynebacterium plasmid png2. | | 1990 | 2110657 |
| effect of low mole fraction of trehalose dicorynomycolate from corynebacterium diphtheriae on water permeability and electrical capacitance of lipid bilayer membranes. | the effect of incorporation of different proportions of trehalose dicorynomycolates (tdc) into lecithin bilayer membranes was studied. it was found that tdc, induces a 14% decrease of water osmotic permeability (42.6 +/- 3.9 to 36.8 +/- 2.7 microns/s) at 1.6 mole%, suggesting that this substance leads to an increase of the degree of packing of the constituent lipid molecules. a condensing effect of tdc was also apparent from membrane electrical capacitance (cm) measurement. by incorporating tdc ... | 1990 | 2111231 |
| [deoxyribonuclease from corynebacterium diphtheriae: dynamics of synthesis and properties]. | diphtheritic bacteria of pw-8 massachusetts strain produced into cultural medium only one nucleotidase--endodnaase. the enzyme was synthesized by the cells during the exponential phase of growth. the dnaase was purified 500-fold and exhibited properties specific to neutral-alkaline dnaases (ph optimum about 7.5, absolute requirements for me2+, single-step mechanism of substrate hydrolysis). the following properties were typical for the enzyme: absence of distinct specificity to structure of base ... | 1990 | 2111600 |
| numerical taxonomy of fluorescent pseudomonas associated with tomato roots. | the phenetic taxonomy of 110 fluorescent bacterial strains, isolated from the roots of tomatoes and other plants was numerically studied through 97 features including 69 assimilation tests. thirty-two reference strains of various pseudomonas spp. were additionally included. the strains clustered into 16 clusters at the 74% similarity level when using jaccard similarity coefficients. almost all field strains belonged to the p. fluorescens/p. putida-complex while none clustered with p. syringae an ... | 1990 | 2112894 |
| [diagnosis of diphtheria]. | | 1990 | 2113126 |
| [corynebacteria of the jk group and their sensitivity to antibacterial drugs]. | | 1990 | 2113801 |
| [survey of microbes in hospital environment]. | bacterial count and species distribution in hospital ward was investigated. it was shown that the in air total bacterial count was maximum in the second season of the year and the number of streptococcus above the standard was in the first season. bacteria in the air of the ward by number was in this order: micrococcus tetragenus, staphylococcus, bacillus subtilis, streptococcus and corynebacterium. according to the number of bacteria on the equipment and door handle of the ward, the order, was ... | 1990 | 2114272 |
| the risk of intentional dissolution of the smear layer after mechanical preparation of root canals. | the root canals of 27 caries-free human cuspids were divided into 3 groups of 9 teeth each. group i was mechanically prepared with reamers and files. alternate irrigation with 5.25% naocl and 3% hydrogen peroxide was used between each instrument. the group ii root canals were prepared with the use of alternate irrigation with the same concentrations of naocl and hydrogen peroxide and finally flushed with 17% edta and naocl solution. group iii was prepared mechanically with the use of sterile dis ... | 1990 | 2115155 |
| molecular cloning and dna sequence analysis of a diphtheria tox iron-dependent regulatory element (dtxr) from corynebacterium diphtheriae. | although the structural gene for diphtheria toxin, tox, is carried by a family of closely related corynebacteriophages, the regulation of tox expression is controlled, to a large extent, by its bacterial host corynebacterium diphtheriae. optimal yields of tox gene products are obtained only when iron becomes the growth-rate-limiting substrate. previous studies suggest that regulation of tox expression is mediated through an iron-binding aporepressor. to facilitate molecular cloning of the tox re ... | 1990 | 2116013 |
| comparative evaluation of nonradiometric bactec and improved oxoid signal blood culture systems in a clinical laboratory. | the bactec nr660 blood culture system, which uses infrared spectroscopy to detect carbon dioxide generated by bacterial growth, was compared with the new medium formulation of the oxoid signal system. two trials were conducted: a comparative study of 88 organisms in simulated blood cultures and a clinical trial of 3,321 paired patient blood culture samples. both trials showed that overall the bactec system performed better in the recovery of organisms. the oxoid system was unable to detect by si ... | 1990 | 2116450 |
| acp broadsheet no 125: july 1990. bacteriological diagnosis of diphtheria. | | 1990 | 2116457 |
| coryneform bacteria in infectious diseases: clinical and laboratory aspects. | coryneform isolates from clinical specimens frequently cannot be identified by either reference laboratories or research laboratories. many of these organisms are skin flora that belong to a large number of taxonomic groups, only 40% of which are in the genus corynebacterium. this review provides an update on clinical presentations, microbiological features, and pathogenic mechanisms of infections with nondiphtheria corynebacterium species and other pleomorphic gram-positive rods. the early lite ... | 1990 | 2116939 |