| proceedings: treatment of a metastasizing murine tumour with corynebacterium parvum. | | 1975 | 1164486 |
| production of auxins by bacteria isolated from the roots of pine seedlings (pinus silvestris l.). | qualitative and quantitative studies were carried out on the production of auxins by coryneform bacteria, the only bacterial types isolated from roots of pine seedlings. almost all isolates were capable of producing auxins in tryptophan containing media. in media without this amino acid only trace or no auxins were produced. most of the bacteria studied synthesized auxins located on the chromatograms run with isopropanol, ammonia, water (10:1:1 v/v) at rf 0.3--0.5. moreover substances with rf va ... | 1975 | 1166831 |
| characterization of hydrogen sulfide-producing bacteria isolated from meat and poultry plants. | a survey of the types of aerobic organisms able to produce h2s on peptone iron agar (levin, 1968), and commonly occurring in meat and poultry plants, revealed that these could be divided into four distinct groups. the ability of representative strains of each type to grow at low temperatures and cause off-odors on chicken muscle was examined. the results are discussed in relation to the role of these organisms in the psychrophilic spoilage of meat and meat products. | 1975 | 1167774 |
| a cat with corynebacterium equi lymphadenitis clinically simulating lymphosarcoma. | a cat with granulomatous lymphadenitis due to corynebacterium equi is described. clinically the cat was diagnosed as having lymphosarcoma. bacteria were cultured from the lymph nodes. | 1975 | 1173231 |
| splenic suppressor macrophages induced in mice by injection of corynebacterium parvum. | spleen cells from c57bl/6n mice injected with killed corynebacterium parvum (cp) had a marked growth inhibitory effect on the in vitro proliferation of rbl-5 murine lymphoma cells. it was most marked 12 to 14 days after injection and was usually no longer detectable later than 21 days. it could be demonstrated at effector cell to target ratios between 20:1 and 5:1 at which normal spleen cells had a growth-promoting effect. addition of cp to an in vitro mixture of spleen cells and tumor cells aug ... | 1975 | 1176773 |
| differential diagnosis of diarrhoea in horses over six months of age. | pertinent questions regarding the history of a horse with diarrhoea are listed, as are diagnostic procedures that might be included in a complete clinical work-up. for purposes of discussion, diarrhoea is regarded as "acute" or "chronic" wherein the former concerns cases where the features of the disease are severe with progressive electrolyte imbalance, dehydration, toxaemia, or other life-threatening manifestations and the latter refers to cases that have been prolonged for a month or more. pa ... | 1975 | 1177243 |
| treatment of diarrhoea in the horse. | | 1975 | 1177248 |
| infection after total knee arthroplasty. | | 1975 | 1178156 |
| a pathological and bacteriological abattoir survey of the reproductive tracts of merino ewes in western australia. | macroscopic examination of 487 ewe reproductive tracts from 18 different sources was made at perth abattoirs. of these, 194 were examined microscopically and 217 bacteriologically. observations were made during march to may, when ewes were not grazing oestrogenic pasture. significant lesions in ovaries or oviducts were rare. macroscopic cysts were found in the uterus or cervix of 159 ewes (32.7%). microscopic lesions, including uterine or cervical cysts and squamous metaplasia or goblet cell hyp ... | 1975 | 1180775 |
| immunoadjuvant activities of cell walls and their water-soluble fractions prepared from various gram-positive bacteria. | the cell walls from all 21 species of gram-positive bacteria examined, except lysozyme-susceptible micrococcus lysodeikticus (nctc 2665) and lysozyme-resistant staphylococcus epidermidis (atcc 155), were found to be definitely adjuvant-active in both stimulation of increased serum antibody levels and induction of delayed-type hypersensitivity to ovalbumin when administered to guinea-pigs as water-in-oil emulsions. using various cell wall lytic enzymes, the immunoadjuvant principles were solubili ... | 1975 | 1180872 |
| [presence of coryneform organisms (c) in cow udders. iii. fermentation and hemagglutination properties as well as pathogenicity of c. uberis]. | altogether 111 strains of c. uberis isolated from cow udders of a dairy herd were studied. only 27 strains gave positive fermentation without gas formation from glucose, 6 strains from maltose, lactose and galactose, 9 strains from maltose, 4 strains from sucrose, and 5 strains from sucrose and lactose. no fermentation was found in 48 strains; 12 strains decomposed various carbohydrates except glucose. statistically significant differences in the slide haemagglutination test (oh), type a, were o ... | 1975 | 1181560 |
| distribution of corynebacterium renale among healthy bulls with special reference to inhabitation of type iii in the prepuce. | distribution of corynebacterium renale among apparently healthy bulls reared in hokkaido was investigated. the organism was detected from 46 (39.3%) of 117 specimens of preputial cavity washing and from 60 (51.7%) of 116 specimens of semen. the isolates studied in this survey belonged to type iii, except a few which belonged to type ii. no type i strain was isolated from any bull. c. renale type iii was isolated from the prepuce in six of seven bulls slaughtered and from urethra in three, but no ... | 1975 | 1186911 |
| [formation of primary alcohols and palmitic acid in the microbiological oxidation of hexadecane]. | forty seven microbial strains oxidized hexadecane to form primary cetol and palmitic acid. the maximum quantitiy of the compounds was accumulated in the exponential phase of growing cultures (for 72 hours) and for 6 to 16 hours of incubation of resting cell suspensions. candida yeast were shown by the gas-liquid chromatography method to be the most active producers of cetol. | 1975 | 1187568 |
| attachment of corynebacterium renale to tissue culture cells by the pili. | one or more cells of corynebacterium renale strains (serologic types, i, ii and iii), which possessed numerous pili, frequently were attached to bhk-21 cells, primary dog kidney cells, and primary rabbit kidney cells. the percentage of the cultured cells to which c renal cells were attached was about 70%. the percentage was less with cells of c renale possessing fewer pili, around 30%. after c renale was treated with the homologous anti-pili serum, the percentage of bhk-21 cells to which bacteri ... | 1975 | 1190607 |
| a case of prosthetic valve endocarditis caused by corynebacterium hofmanni and candida albicans. | the case is described of a 49-year-old woman who developed endocarditis in relation to the prosthetic valve two months after insertion of a starr-edwards mitral valve prosthesis. initially corynebacterium hofmanni was isolated from blood culture. later, while the patient was receiving antibacterial chemotherapy, candida albicans was also isolated and she was treated with 5-fluorocytosine. a cure was effected without the need for further valve replacement. | 1975 | 1191436 |
| [modification of infectious-allergic processes by oral administration of antigens]. | the oral administration of appropriate antigens causes a decrease in sensitization as shown by the models of tuberculin allergy in guinea pigs and of the sensitization of guinea pigs and rabbits to corynebacterium acnes antigens. | 1975 | 1193528 |
| enhanced resistance to corynebacterium pseudotuberculosis infections associated with reduced serum immunoglobulin levels in levamisole-treated mice. | the effect of levamisole (1-2,3,5,6-tetrahydro-6-imidazo[2,1-b]thiazole monohydrochloride) treatment on the course of a corynebacterium pseudotuberculosis infection and the ability of either vaccinated or unvaccinated randomly bred mice to resist challenge were investigated. it was found that either a double treatment of levamisole administered with or without a sublethal inoculation of c. pseudotuberculosis or a single treatment of levamisole alone had a significant effect on the ability of mic ... | 1975 | 1193726 |
| asymptomatic bacteriuria, bacteremia, and other infections due to nsu corynebacteria. | by means of the new medium, nonspecific urethritis (nsu) chocolate agar, nsu corymebacteria were isolated from patients with asymptomatic bacteriuria, bacteremia, cervicitis, conjuctivitis, and pericarditis, and also with bone marrow, wound, and cul-de-sac infections. the nsu corynebacteria were considered the etiologic agents. on the basis of biochemical reactions, antibiotic sensitivity, and complement fixation tests some isolates were the same microorganisms. both patients with conjunctivitis ... | 1975 | 1193819 |
| some aspects of the immunological response in cattle infected with corynebacterium renale. identification of a new serotype of c. renale, type iv. | | 1975 | 1199528 |
| mycoplasmas and 'diphtheroids' in rheumatoid arthritis. | the failure to isolate conventional mycoplasmas from 88 synovial membranes and 119 synovial fluids from patients with proven rheumatoid arthritis using a variety of culture media and techniques agrees with the results of recent workers and suggests that these organisms are unlikely to play a role in the aetiology of the disease. in contrast, 'diphtheroid' organisms were isolated from 27 to 30% of rheumatoid specimens, but not from cultures of non-rheumatoid material. a significantly higher incid ... | 1975 | 1202604 |
| immunological investigation and immunotherapy approaches in cancer patients. | the authors report the preliminary results of a two-step far-reaching investigation carried out on cancer patients to study: 1) the immune conditions of the patients and establish, by a thorough immune monitoring, employing tests of humoral immunity (tetanus toxoid response), of delayed immunity (bcg test, pha-lymphocyte blastogenesis, mif release, skin window) and macrophage immunity (skin window), the chemotherapy effects on the immune conditions and the most suitable time to carry out immunot ... | 1975 | 1203089 |
| haematological changes and iron metabolism in rats after administration of corynebacterium parvum. | administration of 1-4 mg of c. parvum to rats caused a transient and mild normochromic and normocytic anaemia with reticulocytosis. there was also an immediate and marked fall of plasma iron concentration and a moderate increase of total iron binding capacity of plasma. despite increased clearance of 59fe from the plasma there was no significant change of the plasma iron turnover rate. at later intervals after administration of c. parvum an increased incorporation of iron into red blood cells an ... | 1975 | 1203175 |
| activation of the classical and alternate pathways of complement by corynebacterium parvum. | the immunological adjuvant corynebacterium parvum has been to activate the alternate pathway of complement in human and guinea-pig serum. human serum in addition contains anti-c. parvum antibodies leading to activation of the classical complement pathway. the possible role of a c. parvum derived polysaccharide in this activation is considered in relation to the biological effects of the micro-organism. | 1975 | 1204238 |
| comparative toxic effect of the surface lipid of corynebacterium ovis on peritoneal macrophages. | the postphagocytic effect on mouse, rabbit, and guinea pig peritoneal macrophages of a petrol-ether lipid extract from corynebacterium ovis (c. pseudotuberculosis) representing the surface coat of the organism external to the cell wall was investigated by examing three parameters of cytotoxicity, viability assayed by dye exclusion, glycolytic activity, and ultrastructural morphology. the viability test demonstrated a lethal effect on normal and immune mouse macrophages but not on those of the ra ... | 1975 | 1205621 |
| further observations on the inhibition of tumor growth by corynebacterium parvum with cyclophosphamide. i. variation in administration of both agents. | studies from this laboratory have indicated that the administration of cyclophosphamide (cy) and corynebacterium parvum (cp) over a prolonged time to c3h mice with established measurable tumors resulted in complete arrest of tumor growth as well as partial and complete regressions in many instances. the present investigations on optimal dosage, route, frequency, and sequence of administration of cy and cp in the model system were performed to obtain information that could be useful in the design ... | 1975 | 1206740 |
| mchanisms of antitumor action of corynebacterium parvum: nonspecific tumor cell destruction at site of immunologically mediated sensitivity reaction to c. parvum. | mice immunized in the footpad with corynebacterium parvum developed a systemic mechanism with a potential for destroying syngeneic tumor cells. the development of this mechanism of antitumor action depended on the generation of a state of systemic sensitivity to c. parvum antigens, which allowed an immunologically mediated inflammatory response to be focused at the site of a tumor cell challenge or in the bed of an established tumor. this resulted in complete inhibition of growth of the former r ... | 1975 | 1206760 |
| [effect of oleic acid and tween-80 on lysine synthesis by the culture corynebacterium glutamicum]. | the effect of oxidized and unoxidized oleic acid and tween-80 on the growth and lysine synthesis by the producers c. glutamicum strains 95, 8, 28 was investigated. surface active substances like oxidized and unoxidized oleic acid and tween-80 during cultivation of the lysine producers on the glucose medium (the synthetic medium) and the medium with molasses and corn extract either inhibited the culture growth, thus reducing lysine yield, or accelerated the culture growth, thus increasing lysine ... | 1975 | 1208392 |
| proceedings: therapy of methyl cholanthrene induced cba mouse tumours with corynebacterium parvum and irradiated tumour cells. | | 1975 | 1212356 |
| bacterial flora and the diabetic skin. | | 1975 | 1213750 |
| septicaemia due to corynebacterium haemolyticum. | the clinical and microbiological features of a case of septicaemia due to corynebacterium haemolyticum are described. isolation of the organism from blood cultures taken at the time of admission, immediate response to penicillin, presence of agglutinating antibodies in high titre in the patient's serum, and our failure to find evidence of infection with any other pathogen suggests a causative role. | 1975 | 1214013 |
| degradation of aflatoxin b1 by microorganisms. | | 1975 | 1214855 |
| effect of prolonged corynebacterium parvum and cyclophosphamide administration on spontaneously occurring metastases. | | 1975 | 1216089 |
| wimmera rye grass toxicity in western australia. | outbreaks of wimmera rye grass toxicity in the south-west of western australia, and the associated distribution of wimmera rye grass parasitised by anguina sp and corynebacterium sp were investigated. between 1970 and 1974, 58 outbreaks occurred on 26 farms in sheep and cattle grazing pasture, cereal crop, stubble, screenings, or hay containing parasitised wimmera rye grass. morbidity rates up to 77% were observed. clinical signs were characterised by staggering, collapse, periods of convulsions ... | 1975 | 1220656 |
| [study of the phosphatide antigens of corynebacteria. report 4. mechanism of interaction of phosphatides and erythrocytes during the process of hemosensitization]. | | 1975 | 1221717 |
| [model infection with corynebacterium kutscheri in the mouse]. | | 1975 | 1224830 |
| combination of non-specific immunopotentiation with corynebacterium liquefaciens and chemotherapy in tumor-bearing mice. | the effect of combining chemotherapeutics (mitomycin-c, cyclophosphamide, or 5-fluorouracil) and immunopotentiator (anaeobic corynebacterium liquefaciens) against ehrlich ascites carcinoma in mice was examined. mitomycin-c and cyclophosphamide were given intraperitoneally 2 days after the inoculation of tumor cells. 5-fluorouracil was administered intraperitoneally for 7 consecutive days beginning from the second day after inoculation of tumor cells. c. liquefaciens was given intraperitoneally i ... | 1975 | 1225723 |
| corynebacterium hofmanni bacterophage criterion in the taxonomy of corynebacterium genus. | | 1975 | 1227442 |
| [pseudotuberculosis in mice. isolation of corynebacterium kutscheri from the oral cavity and the skin of sick and aparently healthy animals]. | | 1975 | 1235973 |
| new medium for isolation of corynebacterium vaginale from genital specimens. | corynebacterium vaginale was isolated from 48 (23.4%) cervical, vaginal, and urethral swabbings of 205 female outpatients. a new medium modified from peptone starch dextrose agar was used to isolate c. vaginale from most specimens. the new medium contained starch without dextrose with brom cresol purple added. with the exception of certain strains of streptococci, c. vaginale was the only organism isolated from genital specimens that grew and fermented starch on the medium. the new medium provid ... | 1975 | 1236613 |
| effects of estrus and exogenous estrogen on circulating neutrophils and milk somatic cell concentration, neutrophil phagocytosis, and occurrence of clinical mastitis in cows. | in a study involving 56 quarters (14 cows), it was seen that standing estrus did not affect circulating neutrophil and milk somatic cell concentrations, neutrophil phagocytosis, milk production, or occurrence of clinical mastitis. the subcutaneous injection of 17beta-estradiol (e2) (0.05 mg/kg of body weight 2 times daily for 2 consecutive days) did not affect neutrophil phagocytosis or milk somatic cell values. however, a significant increase in circulating neutrophils and a significant decreas ... | 1975 | 1238041 |
| [latent infection with corynebacterium kutscheri in mice after peroral inoculation and its provocation by cortisone (author's transl)]. | latent infection with corynebacterium kutscheri in mice and its provocation by cortisone were studied with a rifampicin-resistant strain of the organism. mice having been infected perorally began to excrete the organisms in feces within 6 hours, and most of them were found to be carrying the organisms in the intestine, especially in the cecum even 90 days after infection. in such state of latency, however, no organisms were detected in other main organs, and neither visible lesions nor serum agg ... | 1975 | 1238258 |
| dairy goat herd health problems. | | 1975 | 1238382 |
| efficacy of antibiotic treatment in cows affected with cystitis and those affected with pyelonephritis due to corynebacterium renale. | | 1975 | 1238865 |
| [peroral infection of corynebacterium kutscheri in mice. ii. in vivo bacterial activities and manifestation of occult infection]. | | 1975 | 1240184 |
| [enzymes of oral anaerobic bacteria capable of causing mixed infection]. | | 1975 | 1240194 |
| [effect of anaerobic corynebacterium on immunologic response of mice]. | | 1975 | 1240247 |
| [biological activities of oral anaerobic corynebacterium]. | | 1975 | 1240249 |
| [effect of macrophages activated by anaerobic corynebacterium on cellular immunity]. | | 1975 | 1240252 |
| [anti-tumor effects of anaerobic corynebacterium]. | | 1975 | 1240280 |
| [classification of corynebacterium renale]. | | 1975 | 1240301 |
| [existence of fimbria in corynebacterium]. | | 1975 | 1240308 |
| [attachment of corynebacterium renale to animal cells by fimbria]. | | 1975 | 1240309 |
| the influence of urea and guanidine chloride on the binding of the binding of the bacterial substrate and inhibitors to hen lysozyme at physiological temperature (40 degrees) (*). | the influence of urea and of guanidine chloride on the binding of the bacterial substrate and of inhibitors such as n-acetylglucosamine or chitotetraose to hen lysozyme were studied at 20 degrees and at 40 degrees c (physiological temperature). the action of urea did not prevent a certain degree of organization of the enzyme compatible with its usual behaviour in the presence of some inhibitors and with its crystallization ; guanidine chloride, already at low concentrations, seemed to have a mor ... | 1975 | 1241284 |
| effect of bacterial wilt on uptake and translocation of phosphorus, sulphur, calcium, and manganese in alfalfa plants. | | 1975 | 1242847 |
| current status of passive immunity to diphtheria and tetanus in the newborn. | the extent of transplacentally derived immunity to the toxins of corynebacterium diphtheriae and clostridium tetani was assessed by a hemagglutination technique using the cord sera of a group of infants recently born in bronx, new york. protective levels of antitoxin to c. diphtheriae were found in 64% of the infants. tetanus antitoxin was present in sufficient quantity for protection in 38% of the cord sera. while this degree of immunity reepresents an improvement over that achieved 20 years ag ... | 1976 | 1245766 |
| responsiveness of senescent mice to the antitumor properties of corynebacterium parvum. | the antitumor properties of corynebacterium parvum have been studied in young (3- to 8-month-old) and aged 18 or more months old) balb/c mice given s.c., i.m., i.p., or i.v. transplants of the highly malignant, weakly immunogenic line 1 lung carcinoma, and in aged (25- to 33-month-old) balb/c mice bearing primary mammary tumors. these aged balb/c mice were shown to be less immunoresponsive than their younger counterparts, and this, in combination with nonimmunological factors, made them more sen ... | 1976 | 1247995 |
| suppression of the incidence of death with spontaneous tumours in dba/2 mice after corynebacterium parvum-mediated rejection of syngeneic tumours. | | 1976 | 1250378 |
| proceedings: immunological mechanisms involved in the inhibition of tumour metastases by corynebacterium parvum. | | 1976 | 1252731 |
| antitumor activity of corynebacterium parvum extracts. | extracts of corynebacterium parvum produced by mild hydrolysis of the whole organisms had antitumor activity if given iv 1 day before iv administration of fibrosarcoma cells or if given ip or sc in admixture with these cells. a lipid component seemed responsible for these effects. unlike whole bacteria, they had little immunotherapeutic activity if given 3 days after sc tumor implantation unless absorbed onto latex. however, organisms treated with acid did not have any immunotherapeutic effect i ... | 1976 | 1255777 |
| further observations on the inhibition of tumor growth by corynebacterium parvum with cyclophosphamide. ii. effect of cortisone acetate. | studies from this laboratory have demonstrated that the administration of cyclophosphamide (cy) and corynebacterium parvum (cp) over a prolonged time to c3h mice with established measurable tumors resulted in complete arrest of tumor growth as well as partial and complete regressions in many instances. a study of the effect of two different doses of cortisone acetate (ca), administered two or five times weekly, on the tumor inhibitory properties of this chemoimmunotherapeutic regimen indicated t ... | 1976 | 1255788 |
| immunotherapy and human tumor immunology. | present knowledge about the immune response to tumors in man is briefly reviewed, and the effects of cancer on immune-system functions are noted. the concepts that human tumors elicit cell-mediated immune responses to tumor antigens are re-examined and modified; for example, cell-mediated immunity may be detectable only at certain stages of tumor growth. introduction of more sensitive methods for detecting antibodies is providing additional evidence for humoral immune responses to tumor-associat ... | 1976 | 1259292 |
| enrichment and isolation of nitrogen fixing hydrogen bacteria. | an enrichment method for nitrogen fixing hydrogen bacteria is described. the procedure invariably resulted in the isolation of yellow-pigmented coryneform bacterial strains assigned to corynebacterium autotrophicum. the procedure included a serial transfer in an ammonium-free mineral liquid medium under an atmosphere of 10% hydrogen, 5% oxygen, 10% carbon dioxide and 75% nitrogen, followed by a short alkali treatment and by streaking on nutrient broth-succinate agar. the ability to fix nitrogen ... | 1976 | 1259514 |
| effect of hydroxamic acids on growth and urease activity in corynebacterium renale. | studies were conducted on the effect of four different hydroxamic acids (ha), hydroxyurea, acetohydroxamic acid, p-flurobenzoylhydroxamic acid and sorbylhydroxamic acid, on the growth and urease activity of corynebacterium renale. the addition of each of these ha, at concentrations ranging form 10(-3) to 10(-5) m, to medium containing urea as the sole nitrogen source resulted in a lengthened lag period of growth the extent of which depended upon the concentration of each ha tested as well as the ... | 1976 | 1260545 |
| effect of corynebacterium parvum on the response to irradiation of a c3h fibrosarcoma. | a methylcholanthrene-induced fibrosarcoma of c3h mice has been used as 5th- to 6th-generation syngeneic transplant in an investigation of the role of corynebacterium parvum as an adjuvant to the therapeutic effect of local irradiation of established tumors. the most effective route for administration of c. parvum in this tumor system was i.v., and the greatest effect of the c. parvum-mediated tumor graft rejection was observed for tumor growing intracutaneously or s.c. an intermediate level of e ... | 1976 | 1260756 |
| [clinical study of amoxicillin used in the otorhinolaryngological field (author's transl)]. | the following results were obtained from oral administration of amoxicillin to 20 cases of acute otorhinolaryngological infections for 5 consecutive days; the daily dose was 1,500 mg for adult and 750mg for child. 1. six cases with acute tonsillitis, 6 with acute pharyngolaryngitis, 5 with acute otitis media, 2 with furuncle of the nose and 1 with acute laryngitis were treated with amoxicillin. this drug was remarkably effective in 2 of 20 cases in total, effective in 15, slightly effective in 1 ... | 1976 | 1263338 |
| relation between the toxogenicity and pyogenicity of corynebacterium ovis in experimentally infected mice. | suspensions of corynebacterium ovis subjected to physical and chemical treatment failed to kill inoculated mice but were able to produce sterile pyogenic lesions. it appears that the exotoxin is different from the pyogenic factor and that the latter is attached to a heat-stable substance in the bacterial cell. mice immunised with antitoxin showed local non-spreading lesions when subsequenly inoculated with washed c ovis cells while unprotected control mice showed a spreading type of infection wh ... | 1976 | 1265358 |
| [a technical problem in meat inspection]. | | 1976 | 1265730 |
| antitumour effect of corynebacterium parvum. possible mode of action. | | 1976 | 1268035 |
| cord factor and related trehalose esters. | | 1976 | 1269070 |
| corynebacterium parvum. | | 1976 | 1269143 |
| gingival flora of the dog with special reference to bacteria associated with bites. | gingival scrapings from dogs were examined to determine their aerobic bacterial flora. of particular interest was the frequent recovery of three unclassified groups of aerobic gram-negative bacteria, iij, ef-4, and m-5, previously associated with human dog-bite infections. although no set pattern was found between the variability and consistency of gingival microbiota as related to age, sex, or breed of dog, a certain characteristic flora can be predicted in the healthy canine gingiva. members o ... | 1976 | 1270595 |
| identification and physiological characterization of the nitrogen fixing bacterium corynebacterium autotrophicum gz 29. | the coryneform hydrogen bacterium strain gz 29, assigned to corynebacterium autotrophicum fixed molecular nitrogen under autotrophic (h2, co2) as well as under heterotrophic (sucrose) conditions. physiological parameters of nitrogen fixation were measured under heterotrophic conditions. the optimal dissolved oxygen concentration for cells grown in a fermenter with n2 was rather low (0.14 mg o2/l) compared with cells grown in the presence of nh+4 (4.45 mg o2/l). c. autotrophicum gz 29 had a doubl ... | 1976 | 1275646 |
| the effects of corynebacterium parvum and surgery on the lewis lung carcinoma and its metastases. | the effects of corynebacterium parvum on the mouse primary lewis lung carcinoma and its metastases were studied. c. parvum was given at the same time as subcutaneous inoculation of tumour or in combination with surgical excision of the primary after 10 days' growth. when intravenous c. parvum was given at the same time as tumour there was a reduction in the primary tumour growth rate. there was a similar reduction in growth if the drug was given intravenously 7 days after tumour inoculation. int ... | 1976 | 1276661 |
| long-chain n-alkanes occurring during microbial degradation of petroleum. | five axenic cultures and a mixed culture were examined for ability to degrade south louisiana, brass river nigerian, anaco venezuelan, and altamont crude oils. a wax was observed during microbial degradation of altamont crude oil, but not during weathering of the oil. the high-boiling n-alkanes in the wax were associated with microbial degradation of the oil and appeared to be similar to components of tarballs found in the open ocean. | 1976 | 1277009 |
| correlation of antitumor chemoimmunotherapy with bone marrow macrophage precursor cell stimulation and macrophage cytotoxicity. | the present investigations have assessed the effects of prolonged cyclophosphamide (cy) and corynebacterium (cp) treatment on the production of bone marrow macrophage precursors [colony-forming cells (cfc)] and on the cytotoxicity of macrophages comprising colonies produced by the cfc. the findings have been correlated with tumor growth in animals receiving the immunochemotherapy. in addition, studies have been directed toward ascertaining whether the administration of cp with cy might lessen th ... | 1976 | 1277129 |
| the effect of corynebacterium parvum in combination with 5-fluorouracil, l-phenylalanine mustard, or methotrexate on the inhibition of tumor growth. | previous reports from this laboratory have demonstrated conclusively that cyclophosphamide administered asynchronously with corynebacterium parvum (cp) results in greater c3h mammary tumor inhibition than that observed with either agent alone. an analysis of this combination has revelaed that the chemotherapeutic component contributes more significantly to tumor inhibition than does the immunotherapeutic one. this study was conducted to investigate the inhibition of c3h mammary tumors by other c ... | 1976 | 1277181 |
| pneumonitis due to corynebacterium equi. | corynebacterium equi, a known cause of pneumonitis in foals, calves, and swine, was isolated from the sputum and bronchial washings of a child with pneumonitis and leukemia. clinical improvement followed the administration of chloramphenicol, and cultures of sputum specimens were sterile until relapse occurred after antibiotic therapy was terminated. cure was achieved with a second course of chloramphenicol therapy. corynebacterium equi was not isolated from 1,181 samples of sputum from other im ... | 1976 | 1277942 |
| presence of pili in species of human and animal parasites and pathogens of the genuscorynebacterium. | the presence of pili in human and animal parasites and pathogens of the genus corynebacterium was examined. c. kutscheri, c. diphtheriae, and c. pseudodiphtheriticum possessed a fairly large number of pili, ranging from dozens to more than a hundred, in 91 to 100% of the bacterial cells. c. equi, c. hoagii, c. xerosis, c. pyogenes, and c. murisepticum had only a small number of pili in 10 to 37% of the bacterial cells. in c. bovis, c. striatum, and c. pseudotuberculosis, pili were detected in on ... | 1976 | 1279007 |
| corynebacterium diphtheriae, skin ulcers and travel abroad. | | 1992 | 1285147 |
| non-toxigenic corynebacterium diphtheriae var gravis. | | 1992 | 1285166 |
| a case of cutaneous diphtheria. | | 1992 | 1285171 |
| chronic contagious ecthyma and caseous lymphadenitis in two boer goats. | | 1992 | 1287954 |
| viability of acid-fast bacilli from gamma-& uv-irradiated lepromatous armadillo tissues infected with mycobacterium leprae. | gamma-irradiated splenic homogenates of armadillos infected with m. leprae proved sterile by conventional tests and media. however, on media for chemoautotrophy, these could repeatedly grow as a single type of acid-fast nocardioform bacterium like the unirradiated specimens, although with a much reduced count. in the slide culture, transition from the initial afb/coccoid bodies, to sporulating mycelia and granules in the final stage, could be observed sequentially. the gamma-irradiated tissue sp ... | 1992 | 1291459 |
| [the efficacy of the adtp-vaccine immunization of children with different courses of the vaccinal period]. | | 1992 | 1291954 |
| [chronic corynebacterium endophthalmitis. apropos of 3 cases]. | only a few isolated cases of endophthalmitis have corynebacterium been implicated as etiology. this diphtheroid, which has been considered for a long time as a nonpathogenic contaminant from the conjunctival flora, may produce systemic diseases usually in immuno-deficient patients. keratitis and endophthalmitis cases have been reported in the literature. we report three cases of chronic endophthalmitis after extracapsular extraction with intraocular chamber posterior lens which are characterized ... | 1992 | 1294592 |
| estimation for model parameters of batch fermentation kinetics. | based on the widely accepted mathematical model of fermentation kinetics, an analytical solution is deduced in this paper. to describe the feature of batch fermentation, the parameters of the fermentation kinetics in the analytical solution (i.e., mumax, ks, beta, yg, yp, and m) are estimated at one strike with powell optimization algorithm coded in fortran-77. the experimental data in the example is quoted from a batch lysine fermentation process using corynebacterium glutamicum. the result sho ... | 1992 | 1295601 |
| effect of crude bacterial lipids on the course of listeria infection in mice. | crude lipids from 37 strains belonging to 32 bacterial species were isolated. by injecting mice with lipids 5 d prior to challenge with a virulent strain of listeria monocytogenes, immunostimulatory activity in 19 preparations was found. in general, lipids of gram-negative bacteria appeared to be more effective. as to bacilli, an extraordinary activity was found in the lipids of bacillus firmus. lipids of various species of the genus listeria were found to be active in approximately one-half of ... | 1992 | 1296929 |
| [activity of ethambutol, isoniazid and rifampicin on corynebacterium urealyticum and corynebacterium jeikeium]. | because corynebacteria and mycobacteria have walls of similar composition, it was of interest to test the effects on resistant corynebacteria of two agents with anti-wall effects, i.e., ethambutol (emb) and isoniazid (inh). rifampicin was also studied to extend previous data and clarify conflicting results in the literature. inh was not active in levels achieved in vivo with standard dosages. the minimal inhibitory concentration (mic) of emb was under serum levels for only three of 78 strains. a ... | 1992 | 1299816 |
| [cutaneous diphtheria in a patient with hiv infection]. | | 1992 | 1301708 |
| [corynebacteria d2 and encrusted cystitis with alkaline urine]. | in the light of an informative clinical case report, the authors emphasise the pathogenic role of corynebacteria d2 in urinary tract disease. this microorganism can be easily detected by bacteriologists by the use of special media and such infection is suggested clinically by urinary tract infection with "sterile", strongly alkaline urine. the clinical features of incrusted cystitis with alkaline urine may be accompanied by serious upper urinary tract complications with renal failure, recurrent ... | 1992 | 1302124 |
| anti-infectious effect of c granulosum-derived p40 immunomodulator given by aerosolization and intranasal instillation. | it is known that c granulosum-derived p40 immunomodulator displays strong anti-microbial effects in mice by the intravenous route. since microbial contamination of humans occurs in many instances via the airways, the effect of p40 on infections was investigated when it was given intranasally or by aerosolization. in order to augment its bioavailability, p40 was derivatized by coupling with polylysine chains (p40-pl). the results showed that p40-pl exercised a significant protective effect, both ... | 1992 | 1306363 |
| association between synthesis and release of cgmp and nitric oxide biosynthesis by hepatocytes. | hepatocytes are known to synthesize nitric oxide (no) from l-arginine via an inducible no synthase. studies were performed to determine the relationship between hepatocyte no production and the stimulation of hepatocyte soluble guanylate cyclase. a combination of lipopolysaccharide (lps), interferon-gamma, tumor necrosis factor, and interleukin-1 stimulates the biosynthesis of large quantities of nitrite and nitrate (no2- + no3-). hepatocyte no2- + no3- production was associated with only small ... | 1992 | 1314486 |
| effects of the membrane action of tetralin on the functional and structural properties of artificial and bacterial membranes. | tetralin is toxic to bacterial cells at concentrations below 100 mumol/liter. to assess the inhibitory action of tetralin on bacterial membranes, a membrane model system, consisting of proteoliposomes in which beef heart cytochrome c oxidase was reconstituted as the proton motive force-generating mechanism, and several gram-positive and gram-negative bacteria were studied. because of its hydrophobicity, tetralin partitioned into lipid membranes preferentially (lipid/buffer partition coefficient ... | 1992 | 1314806 |
| purification and characterization of membrane-bound endoglycoceramidase from corynebacterium sp. | endoglycoceramidase catalyzes the hydrolysis of the linkage between oligosaccharides and ceramides of various glycosphingolipids. we found that a bacterial strain corynebacterium sp., isolated from soil, produced endoglycoceramidase both intracellularly and extracellularly. the intracellular enzyme bound to the cell membrane was solubilized with 1% triton x-100 and purified to homogeneity about 170-fold with 60% recovery. the molecular mass of the enzyme was approximately 65 kda. the enzyme is m ... | 1992 | 1315273 |
| silica-induced precipitation of calcium phosphate in the presence of inhibitors of hydroxyapatite formation. | the promotion and the inhibition of hydroxyapatite formation by various substances were determined by measurement of the induction time of spontaneous precipitation (ti) from supersaturated solutions. silica was found to decrease ti in hepes-buffered (ph 7.2) supersaturated solutions with a wide range of calcium-to-phosphate ratios and concentrations. also, in suspensions of the oral bacteria s. mutans or c. matruchotii in 1 mmol/l calcium, 7.5 mmol/l phosphate, and 50 mmol/l hepes (ph 7.2), sil ... | 1992 | 1315347 |
| effect of 1,1-dimethylhydrazine (udmh) on corynebacterium parvum-associated immunosuppression in mice. | these studies further investigate the immunoenhancement properties of udmh by utilizing corynebacterium parvum-induced immunosuppressed mice as well as evaluating activated macrophage production of reactive oxygen intermediates or their effects. forty-eight hour con a-induced lymphoblastogenic responses from splenocytes isolated from c. parvum and udmh-treated balb/c mice were significantly increased compared with c. parvum alone, although less than normal control mice (no treatment). in vitro b ... | 1992 | 1316318 |
| arcanobacterium haemolyticum sepsis and epstein-barr virus infection. | | 1992 | 1321407 |
| gram-positive bacteria with a high dna g+c content are characterized by a common insertion within their 23s rrna genes. | an insertion of about 100 bases within the central part of the 23s rrna genes was found to be a phylogenetic marker for the bacterial line of descent of gram-positive bacteria with a high dna g + c content. the insertion was present in 23s rrna genes of 64 strains representing the major phylogenetic groups of gram-positive bacteria with a high dna g+c content, whereas it was not found in 23s rrna genes of 55 (eu)bacteria representing gram-positive bacteria with a low dna g + c content and all ot ... | 1992 | 1326592 |
| inhibition of nitric oxide synthesis during endotoxemia promotes intrahepatic thrombosis and an oxygen radical-mediated hepatic injury. | corynebacterium parvum-treated mice produce large amounts of circulating nitrogen oxides and develop a severe liver injury in response to lipopolysaccharide (lps). concurrent administration of ng-monomethyl-l-arginine not only suppresses nitric oxide synthesis in these animals but also profoundly increases the hepatic damage following lps. in this report, we present evidence that the increased hepatic damage from inhibition of nitric oxide synthesis is mediated in part by superoxide and hydroxyl ... | 1992 | 1328440 |
| [surveillance of adverse effects following immunization (aefi)]. | the meeting of working group on adverse events following immunization (aefi) was organized in paris on february 5-6-7 1992. reporting and surveillance of aefi in the european countries was advised to be introduced in each country as the part of monitoring system in this matter. channels for reporting system of aefi should be similar to channels for reporting system of communicable diseases or to system of events following drugs. reporting and surveillance system of aefi in poland as well as prop ... | 1992 | 1335588 |