Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| probiotic supplements beneficially affect tryptophan-kynurenine metabolism and reduce the incidence of upper respiratory tract infections in trained athletes: a randomized, double-blinded, placebo-controlled trial. | prolonged intense exercise has been associated with transient suppression of immune function and an increased risk of infections. in this context, the catabolism of amino acid tryptophan via kynurenine may play an important role. the present study examined the effect of a probiotic supplement on the incidence of upper respiratory tract infections (urti) and the metabolism of aromatic amino acids after exhaustive aerobic exercise in trained athletes during three months of winter training. | 2016 | 27886064 |
| a prebiotic role of ecklonia cava improves the mortality of edwardsiella tarda-infected zebrafish models via regulating the growth of lactic acid bacteria and pathogen bacteria. | in this study, the beneficial prebiotic roles of ecklonia cava (e. cava, ec) were evaluated on the growth of lactic acid bacteria (lab) and pathogen bacteria and the mortality of pathogen-bacteria infected zebrafish model. the result showed that the original e. cava (ec) led to the highest growth effects on three labs (lactobacillus brevis, l. brevis; lactobacillus pentosus, l. pentosus; lactobacillus plantarum; l. plantarum) and it was dose-dependent manners. also, ec, its celluclast enzymatic ... | 2016 | 27192145 |
| dispensability of the [4fe-4s] cluster in novel homologues of adenine glycosylase muty. | 7,8-dihydro-8-deoxyguanine (8og) is one of the most common oxidative lesions in dna. dna polymerases misincorporate an adenine across from this lesion. thus, 8og is a highly mutagenic lesion responsible for g:c→t:a transversions. muty is an adenine glycosylase, part of the base excision repair pathway that removes adenines, when mispaired with 8og or guanine. its catalytic domain includes a [4fe-4s] cluster motif coordinated by cysteinyl ligands. when this cluster is absent, muty activity is dep ... | 2016 | 26613369 |
| metagenomics analysis of microbial communities associated with a traditional rice wine starter culture (xaj-pitha) of assam, india. | this is the first report on the microbial diversity of xaj-pitha, a rice wine fermentation starter culture through a metagenomics approach involving illumine-based whole genome shotgun (wgs) sequencing method. metagenomic dna was extracted from rice wine starter culture concocted by ahom community of assam and analyzed using a miseq(®) system. a total of 2,78,231 contigs, with an average read length of 640.13 bp, were obtained. data obtained from the use of several taxonomic profiling tools were ... | 2016 | 28330225 |
| efficient (3r)-acetoin production from meso-2,3-butanediol using a new whole-cell biocatalyst with co-expression of meso-2,3-butanediol dehydrogenase, nadh oxidase and vitreoscilla hemoglobin. | acetoin (ac) is a volatile platform compound with various potential industrial applications. ac contains two stereoisomeric forms: (3s)-ac and (3r)-ac. optically pure ac is important potential intermediate and widely used as a precursor to synthesize novel optically materials. in this study, chiral (3r)-ac production from meso-2,3-butanediol (meso-2,3-bd) was obtained using recombinant escherichia coli cells co-expressing meso-2,3-butanediol dehydrogenase (meso-2,3-bdh), nadh oxidase (nox) and h ... | 2016 | 27713210 |
| lactobacillus brevis cd2 lozenges prevent oral mucositis in patients undergoing high dose chemotherapy followed by haematopoietic stem cell transplantation. | oral mucositis is a common inflammatory complication in patients undergoing high-dose chemotherapy and radiation followed by haematopoietic stem cell transplantation (hsct). lactobacillus brevis cd2 has been proven efficacious in preventing chemoradiotherapy-induced oral mucositis in squamous cell carcinoma of head and neck. | 2016 | 28848667 |
| thermal treatment of lupin-based milk alternatives - impact on lupin proteins and the network of respective lupin-based yogurt alternatives. | in this study lupin-based milk alternative (lbma), obtained from protein isolate of lupinus angustifolius cv. boregine, was homogenized and was subjected to different heat treatments (unheated; pasteurized: 80°c, 60s; ultra-high temperature heating (uht): 140°c, 10s). upon thermal treatment, lupin proteins, namely β-conglutin and α-conglutin, were stepwise denatured, which was accompanied by the exposure of masked sulfhydryl groups, the decrease of free sulfhydryl groups and reoxidation to disul ... | 2016 | 28460988 |
| effect of combined consumption of lactobacillus brevis kb290 and β-carotene on minor diarrhoea-predominant irritable bowel syndrome-like symptoms in healthy subjects: a randomised, double-blind, placebo-controlled, parallel-group trial. | people with non-pathological diarrhoea-predominant irritable bowel syndrome (ibs-d)-like symptoms are present at a significant level even in healthy populations, but established prophylaxis is lacking. previously, we have found that co-administration of lactobacillus brevis kb290 (kb290) and β-carotene (βc) attenuated murine colitis (potential cause of ibs-d-like symptoms) significantly. here, we investigated the effect of kb290 and βc on minor ibs-d-like symptoms in healthy volunteers. after a ... | 2017 | 28391736 |
| a genetically encoded tool for manipulation of nadp(+)/nadph in living cells. | the redox coenzymes nadh and nadph are broadly required for energy metabolism, biosynthesis and detoxification. despite detailed knowledge of specific enzymes and pathways that utilize these coenzymes, a holistic understanding of the regulation and compartmentalization of nadh- and nadph-dependent pathways is lacking, partly because of a lack of tools with which to investigate these processes in living cells. we have previously reported the use of the naturally occurring lactobacillus brevis h2o ... | 2017 | 28805804 |
| self-cycling fermentation for 1,3-propanediol production: comparative evaluation of metabolite flux in cell recycling, simple batch and continuous processes using lactobacillus brevis n1e9.3.3 strain. | the microbial conversion of biodiesel derived crude glycerol to 1,3-propanediol (1,3-pdo) has attained high industrial value due to the broad range of applications as a monomer (1,3-pdo) in textile, cosmetic and polymer industries. this fine chemical through biological production addressed several limitations of the chemical process like high temperatures, pressure and expensive catalysts. in this study 1,3-propanediol production was achieved from a non-pathogenic lactic acid bacterial strain la ... | 2017 | 28760443 |
| complete genome sequence of the sourdough isolate lactobacillus zymae aca-dc 3411. | lactobacillus zymae is a gram-positive lactic acid bacterium belonging to the lactobacillus brevis clade. here, we report the first complete genome sequence of l. zymae aca-dc 3411, which was isolated from traditional greek wheat sourdough. whole-genome analysis may reveal adaptive traits of strain aca-dc 3411 in the sourdough ecosystem. | 2017 | 28751400 |
| three-dimensional structures and functional studies of two gh43 arabinofuranosidases from weissella sp. strain 142 and lactobacillus brevis. | arabinofuranosidases degrade arabinose-containing oligo and polysaccharides, releasing l-arabinose, which is a potentially useful sugar, shown to reduce glycemic response under certain conditions. arabinofuranosidases (arafs) are frequently found in gh43, one of the most common gh-families encoded in genomes in gut microbiota, and hence it is of interest to increase understanding of the function of these enzymes in species occurring in the gut. here we have produced, characterized and solved the ... | 2017 | 28485897 |
| lactic acid bacteria population dynamics during spontaneous fermentation of radish (raphanus sativus l.) roots in brine. | the aim of the present study was to assess the microecosystem development and the dynamics of the lactic acid bacteria population during spontaneous fermentation of radish (raphanus sativus l.) roots in brine at 20 and 30 °c. in both temperatures, lactic acid bacteria prevailed the fermentation; as a result, the ph value was reduced to ca. 3.6 and total titrable acidity increased to ca. 0.4% lactic acid. enterococci population increased and formed a secondary microbiota while pseudomonads, enter ... | 2017 | 28466306 |
| impact of thistle rennet from carlina acanthifolia all. subsp. acanthifolia on bacterial diversity and dynamics of a specialty italian raw ewes' milk cheese. | caciofiore della sibilla is an italian specialty soft cheese manufactured with sopravissana raw ewes' milk and thistle rennet prepared with young fresh leaves and stems of carlina acanthifolia all. subsp. acanthifolia, according to an ancient tradition deeply rooted in the territory of origin (mountainous hinterland of the marche region, central italy). in this study, the impact of thistle rennet on the bacterial dynamics and diversity of caciofiore della sibilla cheese was investigated by apply ... | 2017 | 28558331 |
| probiotic-mediated blueberry (vaccinium corymbosum l.) fruit fermentation to yield functionalized products for augmented antibacterial and antioxidant activity. | the aim of this study was to investigate the fermentation of blueberry fruit with selected probiotic bacteria (bacillus amyloliquefaciens and lactobacillus brevis) and yeast (starmerella bombicola) isolated from fermented starfish for the extraction of functionalized products for biomedical applications. all probiotic-based fermented extracts showed augmented antibacterial and antioxidant activity compared to the control. biochemical parameters of viable cell count, titratable acidity, total phe ... | 2017 | 28690159 |
| lactobacilli-lactoferrin interplay in chlamydia trachomatis infection. | in the cervicovaginal microenvironment, lactobacilli are known to protect against genital infections and, amongst the host defence compounds, lactoferrin has recently acquired importance for its anti-microbial and anti-inflammatory properties. an abnormal genital microenvironment facilitates the acquisition of pathogens like chlamydia trachomatis, the leading cause of bacterial sexually transmitted infections worldwide. the aim of our study is to investigate the effects of lactobacillus crispatu ... | 2017 | 28505248 |
| the oxygen-inducible conversion of lactate to acetate in heterofermentative lactobacillus brevis atcc367. | lactobacillus brevis is an obligatory heterofermentative lactic acid bacterium that produces high levels of acetate which improves the aerobic stability of silages against deterioration by yeasts and molds. however, the mechanism involved in acetate accumulation has yet to be understood. here, experimental evidence indicated that aerobiosis resulted in the conversion of lactate to acetate after glucose exhaustion in l. brevis atcc367 (genbank accession number nc_008497). to elucidate the convers ... | 2017 | 28842545 |
| microbial production of mannitol by lactobacillus brevis 3-a5 from concentrated extract of jerusalem artichoke tubers. | in the present study, the conversion of the extract of jerusalem artichoke tubers for mannitol production by lactobacillus brevis 3-a5 was investigated. when the bacterium utilized enzymatic hydrolysates of jerusalem artichoke extract as the main substrates in batch fermentation, the significant decrease in mannitol productivity was observed when the initial concentration of reducing sugar increased. then, a strategy of continuous fed-batch fermentation was adopted for improving mannitol product ... | 2017 | 28833484 |
| correction to: fuke, aizawa, suganuma, takagi, and naito, effect of combined consumption of lactobacillus brevis kb290 and β-carotene on minor diarrhoea-predominant irritable bowel syndrome-like symptoms in healthy subjects: a randomised, double-blind, placebo-controlled, parallel-group trial. | 2017 | 28817999 | |
| in vitro evaluation of the probiotic and safety properties of bacteriocinogenic and non-bacteriocinogenic lactic acid bacteria from the intestines of nile tilapia and common carp for their use as probiotics in aquaculture. | in this study, seven bacteriocinogenic and non-bacteriocinogenic lab strains previously isolated from the intestines of nile tilapia and common carp and that showed potent antibacterial activity against host-derived and non-host-derived fish pathogens were assayed for their probiotic and safety properties so as to select promising candidates for in vivo application as probiotic in aquaculture. all the strains were investigated for acid and bile tolerances, transit tolerance in simulated gastroin ... | 2017 | 28752423 |
| chemoenzymatic synthesis of statine side chain building blocks and application in the total synthesis of the cholesterol-lowering compound solistatin. | the synthesis and enzymatic reduction of several 6-substituted dioxohexanoates are presented. two-step syntheses of tert-butyl 6-bromo-3,5-dioxohexanoate and the corresponding 6-hydroxy compound have been achieved in 89% and 59% yield, respectively. regio- and enantioselective reduction of these diketones and of the 6-chloro derivative with alcohol dehydrogenase from lactobacillus brevis (lbadh) gave the (5s)-5-hydroxy-3-oxo products with enantiomeric excesses of 91%, 98.4%, and >99.5%, respecti ... | 2017 | 28751276 |
| multiple genome sequences of exopolysaccharide-producing, brewery-associated lactobacillus brevis strains. | lactobacillus brevis represents one of the most relevant beer-spoiling bacteria. besides strains causing turbidity and off flavors upon growth and metabolite formation, this species also comprises strains that produce exopolysaccharides (epss), which increase the viscosity of beer. here, we report the complete genome sequences of three eps-producing, brewery-associated l. brevis strains. | 2017 | 28663299 |
| development of a propidium monoazide-polymerase chain reaction assay for detection of viable lactobacillus brevis in beer. | the spoilage of beer by bacteria is of great concern to the brewer as this can lead to turbidity and abnormal flavors. the polymerase chain reaction (pcr) method for detection of beer-spoilage bacteria is highly specific and provides results much faster than traditional microbiology techniques. however, one of the drawbacks is the inability to differentiate between live and dead cells. in this paper, the combination of propidium monoazide (pma) pretreatment and conventional pcr had been describe ... | 2017 | 28633981 |
| anti-inflammatory potential of a heat-killed lactobacillus strain isolated from kimchi on house dust mite-induced atopic dermatitis in nc/nga mice. | atopic dermatitis (ad) is an allergic skin disease driven by the th2-prone immune response. therefore, a fundamental approach to restoring the th1/th2 balance is needed to treat ad. | 2017 | 28632956 |
| effect of ensiling and silage additives on biogas production and microbial community dynamics during anaerobic digestion of switchgrass. | silage processing has a crucial positive impact on the methane yield of anaerobic treated substrates. changes in the characteristics of switchgrass after ensiling with different additives and their effects on methane production and microbial community changes during anaerobic digestion were investigated. after ensiling (ck), methane yield was increased by 33.59% relative to that of fresh switchgrass (fs). in comparison with the ck treatment, methane production was improved by 17.41%, 13.08% and ... | 2017 | 28577484 |
| clinical and microbiological effects of the adjunctive use of probiotics in the treatment of gingivitis: a randomized controlled clinical trial. | to evaluate the efficacy of a probiotic combination in the treatment of gingivitis and to assess its impact on the subgingival microbiota. | 2017 | 28556062 |
| comparison of acyclovir and multistrain lactobacillus brevis in women with recurrent genital herpes infections: a double-blind, randomized, controlled study. | we performed a randomized double-blind controlled trial to compare the efficacy and safety of multistrain probiotic and acyclovir in women patients with recurrent genital herpes simplex virus type 2 (hsv-2) infections. eighty-one patients enrolled in the study were being treated with multistrain lactobacillus brevis one vaginal capsule every 12 h and oral acyclovir 400 mg twice daily for 6 months. of 53 patients who completed both treatment courses, no important differences were identified betwe ... | 2017 | 28852985 |
| monitoring of wheat lactic acid bacteria from the field until the first step of dough fermentation. | the present work was carried out to retrieve the origin of lactic acid bacteria (lab) in sourdough. to this purpose, wheat lab were monitored from ear harvest until the first step of fermentation for sourdough development. the influence of the geographical area and variety on lab species/strain composition was also determined. the ears of four triticum durum varieties (duilio, iride, saragolla and simeto) were collected from several fields located within the palermo province (sicily, italy) and ... | 2017 | 27889157 |
| dynamics of microbial community during ensiling direct-cut alfalfa with and without lab inoculant and sugar. | to gain deeper insights into the clostridial community dynamics and chemical transformations during the ensiling of alfalfa. | 2017 | 28370869 |
| evaluation of tyrosinase inhibitory and antioxidant activities of angelica dahurica root extracts for four different probiotic bacteria fermentations. | angelica dahurica root (adr), which shows strong antioxidant activity, is used in chinese medicine. this study evaluated the tyrosinase inhibitory and antioxidant activities of adr extracts fermented by four different probiotic bacteria: bifidobacterium bifidum, bifidobacterium lactis, lactobacillus acidophilus, and lactobacillusbrevis. the adr was first extracted using distilled water, 70% ethanol, and ethyl acetate, and then fermented by probiotic bacteria. the physiological characteristics of ... | 2017 | 28254340 |
| effect of magnesium acetate on the antimold activity of lactobacillus. | the antimold activity of lactic acid bacteria (lab) is used in food biopreservation. the aim of this study was to evaluate the effect of magnesium acetate added to de man rogosa sharpe (mrs) medium on the antimold activity of three lab strains ( lactobacillus plantarum , lactobacillus brevis , and lactobacillus fermentum ) against molds contaminating food ( aspergillus oryzae , aspergillus niger , penicillium chrysogenum , fusarium avenaceum , and rhizopus arrhizus ) and their ability to produce ... | 2017 | 28221876 |
| microbiological and biochemical aspects of inland pecorino abruzzese cheese. | little is known on physicochemical and biochemical characteristics of "pecorino" abruzzese cheese in l'aquila province, an artisanal cheese produced from ewe raw full-cream milk. three batches of inland "pecorino" abruzzese cheese were examined for microbiological, compositional, biochemical and sensory characteristics at the aim of isolating and storing in a bacterial collection, indigenous strain to preserve the microbial biodiversity present in this cheese, to a possible definition of a pdo. ... | 2017 | 28280791 |
| utility of thermostable xylanases of mycothermus thermophilus in generating prebiotic xylooligosaccharides. | xylooligosaccharides as emerging prebiotics are able to promote the growth of probiotic bacteria. in the present study, four neutral, thermostable xylanases (mtxyn11a, mtxyn11at, mtxyn11b, and mtxyn11c) from compost fungus mycothermus thermophilus cgmcc3.18119 were overexpressed in pichia pastoris gs115 and used to produce xylooligosaccharides from beechwood xylan. the enzymes showed similar enzymatic properties (maximal activities at ph 6.0-6.5 and 65 °c) but varied in catalytic efficiency and ... | 2017 | 28067041 |
| adjunctive efficacy of probiotics in the treatment of experimental peri-implant mucositis with mechanical and photodynamic therapy: a randomized, cross-over clinical trial. | to evaluate the adjunctive clinical efficacy of probiotics in the treatment of peri-implant mucositis (p-im) with professionally administered plaque removal (papr) and photodynamic therapy (pdt). | 2017 | 28032908 |
| characteristics of surface layer proteins from two new and native strains of lactobacillus brevis. | in this work, some important characteristics of surface layer (s-layer) proteins extracted from two new and native lactobacillus strains, l.brevis km3 and l.brevis km7, were investigated. the presence of s-layer on the external surface of l.brevis km3 was displayed by thin sectioning and negative staining. sds-page analysis were shown same dominant protein bands approximately around 48kda for both s-layer proteins. moreover, the s-layer reappeared when licl treated cells were allowed to grow aga ... | 2017 | 27984145 |
| thermodynamic activity-based intrinsic enzyme kinetic sheds light on enzyme-solvent interactions. | the reaction medium has major impact on biocatalytic reaction systems and on their economic significance. to allow for tailored medium engineering, thermodynamic phenomena, intrinsic enzyme kinetics, and enzyme-solvent interactions have to be discriminated. to this end, enzyme reaction kinetic modeling was coupled with thermodynamic calculations based on investigations of the alcohol dehydrogenase from lactobacillus brevis (lbadh) in monophasic water/methyl tert-butyl ether (mtbe) mixtures as a ... | 2017 | 27813314 |
| lactobacillus sps. lipase mediated poly (ε-caprolactone) degradation. | polymer degradation through lipase appears to be an enthralling alternative to bulk chemical routes. poly (ε-caprolactone) (pcl) is an artificial polyester that can be degraded by microbes and enzymes like lipases and esterases. the environmental degradation of pcl is dependent on the activity of bacteria that characterization techniques such as thermogravimetric analysis, differential thermal are widely present in the ecosystem. in this study, three different lipases derived from lactobacillus ... | 2017 | 27865950 |
| novel bioactive from lactobacillus brevis dsm17250 to stimulate the growth of staphylococcus epidermidis: a pilot study. | commensal skin microbiota plays an important role in both influencing the immune response of the skin and acting as a barrier against colonisation of potentially pathogenic microorganisms and overgrowth of opportunistic pathogens. staphylococcus epidermidis is a key constituent of the normal microbiota on human skin. it balances the inflammatory response after skin injury and produces antimicrobial molecules that selectively inhibit skin pathogens. here we describe lactobacillus brevis dsm17250 ... | 2017 | 27824277 |
| probiotic and antioxidant properties of selenium-enriched lactobacillus brevis lse isolated from an iranian traditional dairy product. | the present study was designed to isolate a highly selenium-tolerant lactobacillus strain from an iranian traditional dairy product named as spar. different criteria such as tolerance to the low ph, simulated gastric juice (sgj), simulated intestinal juice (sij) and bile salts tolerance as well as caco-2 cell adhesion assay were examined to evaluate the probiotic potentials of the selected isolate. furthermore, the antioxidant properties of the isolate cultivated in medium containing and free of ... | 2017 | 28159215 |
| enhanced production of gamma-aminobutyric acid by optimizing culture conditions of lactobacillus brevis hye1 isolated from kimchi, a korean fermented food. | this study evaluated the effects of culture conditions, including carbon and nitrogen sources, l-monosodium glutamate (msg), and initial ph, on gamma-aminobutyric acid (gaba) production by lactobacillus brevis hye1 isolated from kimchi, a korean traditional fermented food. l. brevis hye1 was screened by the production analysis of gaba and genetic analysis of the glutamate decarboxylase gene, resulting in 14.64 mm gaba after 48 h of cultivation in mrs medium containing 1% (w/v) msg. in order to i ... | 2017 | 27880963 |
| 2-pyrrolidone synthesis from γ-aminobutyric acid produced by lactobacillus brevis under solid-state fermentation utilizing toxic deoiled cottonseed cake. | there is an increasing demand of γ-aminobutyric acid (gaba) as drug and food additive, as well as feedstock to produce 2-pyrrolidone, a precursor for the synthesis of nylon 4. 2-pyrrolidone is a petrochemical and depleting reserve which raises concern for its bio-based production. the study herein describes bio-based economical gaba production from lactobacillus brevis by solid-state fermentation (ssf) using toxic deoiled cottonseed cake (csc) as substrate. in general, the use of cottonseed cake ... | 2017 | 27646908 |
| common distribution of gad operon in lactobacillus brevis and its gada contributes to efficient gaba synthesis toward cytosolic near-neutral ph. | many strains of lactic acid bacteria (lab) and bifidobacteria have exhibited strain-specific capacity to produce γ-aminobutyric acid (gaba) via their glutamic acid decarboxylase (gad) system, which is one of amino acid-dependent acid resistance (ar) systems in bacteria. however, the linkage between bacterial ar and gaba production capacity has not been well established. meanwhile, limited evidence has been provided to the global diversity of gaba-producing lab and bifidobacteria, and their mecha ... | 2017 | 28261168 |
| heterogeneity between and within strains of lactobacillus brevis exposed to beer compounds. | this study attempted to investigate the physiological response of six lactobacillus brevis strains to hop stress, with and without the addition of mn(2+) or ethanol. based on the use of different fluorescent probes, cell viability and intracellular ph (phi) were assessed by fluorescence microscopy combined with flow cytometry, at the single cell level. the combined approach was faster than the traditional colony based method, but also provided additional information about population heterogeneit ... | 2017 | 28261191 |
| influence of the experimental setup on the determination of enzyme kinetic parameters. | for the design of bioconversion processes parallel experimentation in microtiter plates is commonly applied to reduce the experimental load, although data accuracy and reproducibility are often reduced. in an effort to quantify the impact of different microscale experimental systems on the estimation of enzyme kinetic parameters from progress curves, we comprehensively evaluated the enzymatic reduction of acetophenone in both open and closed polystyrene and quartz microtiter plates as well as qu ... | 2017 | 27790860 |
| physiology-oriented engineering strategy to improve gamma-aminobutyrate production in lactobacillus brevis. | gamma-aminobutyrate (gaba) is an important chemical in the pharmaceutical field. gaba-producing lactic acid bacteria (lab) offer the opportunity of developing this health-oriented product. in this study, the gada, gadb, gadc, gadcb, and gadca gene segments of lactobacillus brevis were cloned into pmg36e, and strain lb. brevis/pmg36e-gada was selected for thorough characterization in terms of gaba production after analysis of gad activities. subsequently, a physiology-oriented engineering strateg ... | 2017 | 28067044 |