Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| nontraumatic clostridium septicum gangrenous myonecrosis. | nontraumatic clostridium septicum infections may present as either septicemia or as metastatic myonecrosis. most of these infections occur in debilitated patients with diabetes who are receiving cancer chemotherapy. the majority have a hematologic abnormality or a carcinoma of the colon. usually there is an ulcerative lesion of the gastrointestinal tract that serves as the portal of entry. while most of these patients die from overwhelming sepsis, our patient was debrided early and treated promp ... | 1983 | 6628141 |
| acute abomasitis due to clostridium septicum infection in experimental sheep. | 1983 | 6606419 | |
| isolation of clostridium septicum from diseased chickens in broiler farms. | 1982 | 7161998 | |
| clostridium septicum infections and malignancy. | 1982 | 7112192 | |
| susceptibility of clostridium septicum to 23 antimicrobial agents. | the in vitro susceptibility of clostridium septicum was studied with a microtiter broth dilution method. several antimicrobial agents demonstrated consistently good activity against the organism. | 1981 | 7325648 |
| clostridium septicum infection and malignancy. | evidence mounts favoring the relationship, albeit unexplained, between clostridium septicum infection and malignancy, particularly hematologic or intestinal malignancy. seven patients with c. septicum gangrene or sepsis have been treated at the massachusetts general hospital in the years 1977-79. all of these patients have had associated malignant disease: four patients had colon adenocarcinomas, two patients had acute myeloblastic leukemias, and one patient had breast carcinoma. in six of the s ... | 1981 | 7212798 |
| successful therapy of clostridium septicum sepsis in a child with burkitt's lymphoma. | the association between clostridium septicum sepsis in patients with malignant disease has been frequently documented. a presentation with fever, neutropenia, vomiting, and an acute abdomen is characteristic of this anaerobic infection which has been uniformly fatal in children with acute leukemia. we report the unusual course and the successful treatment of an adolescent with an abdominal burkitt's lymphoma with leukemic transformation and clostridium septicum sepsis and cellulitis. | 1981 | 6786126 |
| suppurative abomasitis associated with clostridium septicum infection. | a 1-week-old calf and two 1-month-old lambs from different farms in eastern south dakota had severe abomasitis characterized by diffuse suppurative inflammation, edema, and emphysema. clostridium septicum in the abomasal wall of each was identified by immunofluorescence and isolation. the lesions and microbiologic findings established the disease as braxy, a condition infrequently reported in the united states and thought to affect sheep only. | 1981 | 7204251 |
| [clostridium septicum bacteremia in a diabetic patient (author's transl)]. | this report concerns the clinical and bacteriological study of a female diabetic who presented with a febrile illness of sudden onset and acute toxemia. physical examination at admission was unrewarding. a few hours after admission lesions characteristic of gas gangrene appeared in the right upper limb without prior trauma, and a clostridial infection was suspected. bacteriological studies of the exudate and of the patient's blood led to the isolation of clostridium septicum, thus confirming the ... | 1981 | 7218925 |
| occult clostridial myonecrosis. | nontraumatic gas gangrene is extremely rare. it usually occurs following ulceration or perforation of an abdominal or pelvic viscus in persons having impaired host immune defenses. a fatal case of nontraumatic clostridium septicum septicemia and myonecrosis in an elderly diabetic man with a perforated colon carcinoma is presented. the case illustrates the occult manner in which such cases typically present and the fulminant course of this disease. the need for rapid diagnosis and the current rec ... | 1981 | 7235340 |
| nontraumatic clostridial myonecrosis: an infectious disease emergency. | a 64-year-old man presented with a history of four days of lower abdominal pain and 12 hours of cutaneous discoloration, bullae formation, and swelling of the soft tissues of abdominal wall and right thigh. myonecrosis of abdominal wall and an adenocarcinoma of the cecum were found at operation. cultures of blood and fluid from the bullae yielded clostridium septicum. nontraumatic clostridial myonecrosis is a fulminant, usually fatal disease that is most often the result of bacteremia from an oc ... | 1981 | 7235341 |
| clostridium septicum infection in cattle in the united states. | 1981 | 7309612 | |
| cerebritis due to clostridium septicum. | 1980 | 7192812 | |
| the effects of laboratory animal diets on the potency tests of bacterial vaccines. | comparative studies of the responses elicited by mice fed on pcd and ffg diets to a number of bacterial vaccines have shown a significant reduction in the immune response to tetanus toxoid but not to clostridium septicum toxoid and increased resistance to challenge with e. coli and syngeneic tumour cells but not to pasteurella multocida. these differences cannot readily be explained in terms of differences between the identifiable constituents of the diets and illustrte the dangers of vaccine po ... | 1980 | 6995215 |
| [ultrastructure of clostridium septicum]. | the study of cl. septicum by means of electron microscopy revealed that these organisms had peritrichously located flagella and the five-layer cell wall. the formation of small oval spores was observed by the end of the first day. the first sign of sporulation was the appearance of the prespore membrane followed by the formation of the prespore; the formation of the spore coat and the spore cortex began simultaneously at stage iv. the spore coat appeared first as short osmiphil scales. they were ... | 1980 | 7435021 |
| clostridium septicum infection associated with colonic carcinoma and hematologic abnormality. | six patients with clostridium septicum sepsis seen at duke university medical center over a two-year period also had other abnormalities, consisting of hematologic disorders in 3 and colon tumors in 3. three patients died of sepsis; 2 survived following disarticulation of the arm to control gas gangrene, while the sixth patient survived the sepsis but died of metastatic disease. when anaerobic cultures are positive for c. septicum, antibiotics should be given immediately. the high incidence of u ... | 1980 | 6934562 |
| the haemorrhagic exudate and its possible relationship to neurogenic inflammation. | the morphological effects of an aqueous solution of nistatin, of clostridium septicum and tityus serrulatus toxins, of bothrops jararaca and agkistrodon piscivorus venoms on the vessels of the tendinous portion of the diaphragm were investigated in guinea-pigs. it was demonstrated that all these substances, when injected intrapleurally induced not only an increase in the permeability of venules but also haemorrhages originating at this segment of the microcirculation. red cells were shown to esc ... | 1980 | 7400880 |
| neutropenic enterocolitis and clostridium septicum infection in patients with agranulocytosis. | two patients with previously undiagnosed agranulocytosis had rapidly fatal clostridium septicum sepsis and neutropenic enterocolitis. this toxigenic organism has a known predilection for cecal lesions. the association reported herein suggests that c septicum may be the cause of this necrotizing enteropathy. | 1980 | 7387278 |
| gas gangrene: a postoperative complication. | gas gangrene, also known as clostridial myonecrosis, is a severe and acute infection usually caused by clostridium septicum, which may contaminate a wound. on rare occasions it is a complication of elective bone surgery, although it is usually found in elderly persons after hip surgery. the onset is usually sudden and it may occur from 6 hr. to 3 days after tissue injury. diagnosis may be difficult because of the similarity of symptoms to those of anaerobic cellulitis. treatment consists of surg ... | 1980 | 7264230 |
| immunogenicity of clostridium septicum in guinea pigs. | five strains of clostridium septicum were used to prepare bacterins, bacterin-toxoids, toxoid, and combinations of bacterins or bacterin-toxoids. these preparations were tested for immunogenicity in guinea pigs vaccinated subcutaneously with 1.0 ml of product. usually, a second vaccination was given 21 to 24 days later. the immunity of groups of vaccinated guinea pigs was challenged with as many as 22 strains of c septicum. when challenge exposed with homologous strains at 21 to 24 days after on ... | 1979 | 525895 |
| postoperative clostridium septicum dermatitis simulating toxic epidermal necrolysis. | widespread detachment of the epidermis as a result of clostridium septicum infection after a laparotomy for intestinal obstruction is described. a clinicopathological picture, hitherto undescribed, is outlined. | 1979 | 472950 |
| [clostridium septicum infection in acute leukemia]. | 1979 | 286885 | |
| necrotising enterocolitis associated with invasion by clostridium septicum complicating cyclic neutropaenia. | a fatal case of necrotising enterocolitis complicating cyclic neutropaenia in a 17-year-old boy is reported. the episode of enterocolitis was characterised by fulminant, generalised peritonitis associated with necrosis and gas formation in the wall of the ileum and caecum. clostridium septicum was grown from premortem blood cultures and gram positive bacilli typical of this organism were present in histological sections of the bowel wall. necrotising enterocolitis in this and previously reported ... | 1979 | 292384 |
| clostridium septicum bacteremia. its clinical significance. | the medical records of 59 patients with clostridium septicum bacteremia were reviewed; 42 (71 per cent) of these patients had malignancies. one half had hematologic malignancies, and one half had solid tumors. of the 21 patients with solid tumors, 14 (67 per cent) had cancer of the colon. among these patients, the cecum was the most frequent site of malignancy. the cecum and distal ileum were the most probable portals of entry for c. septicum bacteremia among the 28 patients examined at autopsy. ... | 1979 | 420252 |
| differentiation in the cytotoxicity between hemorrhagic and necrotizing principles produced by clostridium septicum. | 1979 | 541869 | |
| analysis of amines and other bacterial products by head-space gas chromatography. | a gas chromatographic (gc) head-space technique is presented, which is suitable for the analysis of volatile products in bacterial broth cultures. this is exemplified by studies on clostridium septicum, klebsiella pneumoniae and proteus mirabilis. the media were acidified or made alkaline and after heating, samples of the gas phase above the media were directly injected into the gas chromatograph. a gas chromatograph equipped with dual columns and flame ionization detectors was used, employing p ... | 1978 | 358746 |
| clostridium septicum infection in childhood leukemia: report of a case and review of the literature. | overwhelming clostridium septicum infection is a rare occurrence in children. it is seen almost exclusively as a complication of acute leukemia. a high index of suspicion in the leukemic child with an acute abdomen is the key to early diagnosis and improved survival. a case in a 13-year-old girl with acute myelogenous leukemia is reported and six pediatric cases in the literature were reviewed. | 1977 | 268232 |
| multiple hepatic tumors and peliosis hepatis in fanconi's anemia treated with androgens. | we report the case of a 13-year-old boy who was known to have fanconi's anemia for five years. for treatment of this condition he was given androgens and corticosteroids. two months before his death, severe varicella developed complicated by pneumonia, jaundice, and prolonged fever; all of which resolved during a five-week hospitalization. three weeks later he died of clostridium septicum sepsis caused by necrotizing enterocolitis. at autopsy he was found to have multiple hepatocellular neoplasm ... | 1977 | 199056 |
| purification of clostridium toxoids. | a two-step fractionation procedure was applied for purification and concentration of the individual clostridium toxoids. the toxoids were precipitated with hydrochloric acid in the presence of sodium sextametaphosphate, then antigenic fractions were separated from inactive contaminants by sephadex g-75 filtration. specific activity of the preparations thus obtained, as determined by mancini radial immunodiffusion, was 150--565 binding units per mg of protein nitrogen for clostridium perfringens ... | 1977 | 70974 |
| clostridium septicum in childhood leukaemia. | 1977 | 73090 | |
| growth of clostridium tertium and clostridium septicum in chemically defined media. | defined media for the growth of clostridium tertium and clostridium septicum are described. the requirements for growth of these two species are compared with each other and with those of clostridium perfringens. | 1976 | 180884 |
| chronic clostridium septicum infection of a tibial fracture: a case report. | an open transverse fracture of the mid-shaft of the tibia of a professional footballer became infected by clostridium septicum and, after early compression plating, required surgical intervention on three further occasions and extensive antibiotic treatment before healing occurred. clostridial infection is a recognized complication of open fractures contaminated with soil, and the necrotizing toxins produced by the c. septicum were probably responsible for the persistence of this infection. infe ... | 1976 | 1002285 |
| electron capture gas chromatography study of the acid and alcohol products of clostridium septicum and clostridium chauvoei. | the metabolic products produced by several strains of clostridium septicum obtained from patients and animals, along with strains of clostridium chauvoei, were studied in chopped meat glucose medium by electron capture gas-liquid chromatography (ec-glc). the strains of c. septicum and c. chauvoei were shown to comprise five different metabolic groups. both the ec-glc study and the o and h antigenic study performed previously showed that strains of c. septicum comprise a heterogeneous group. one ... | 1976 | 1254716 |
| studies on mode of action of a bacteriocin from clostridium septicum. | a bacteriocin was found in the supernatant fluid of clostridium septicum strain ovinus. sensitivity to the bacteriocin was confined to other strains of c. septicum and to strains of c. chauvoei; the other gram-positive and gram-negative bacteria tested for sensitivity were unaffected by the bacteriocin. the bacteriocin killed sensitive cells rapidly but cell lysis did not appear to be involved. the bacteriocin inhibited protein and rna synthesis immediately after its addition to sensitive cells; ... | 1976 | 1253001 |
| preparation and evaluation to clostridium septicum toxoid. | clostridium septicum was grown under controlled conditions to produce high levels of alpha toxin. the toxin was toxoided and concentrated by ultrafiltration. the toxoided alpha toxin retained immunizing properties. the concentrated toxoid, when formulated on total combining power, in monovalent or multivalent clostridial products, provided protection to rabbits against direct challenge with cl. septicum spores. the toxoided alpha toxin produced antitoxin levels which exceeded current minima. | 1976 | 1001826 |
| potency testing of clostridium septicum bacterins in sheep and laboratory animals. | the immunogenic potency of bacterins containing clostridium septicum was evaluated in mice, hamsters, guinea pigs, rabbits and sheep to establish potency requirements for these bacterins. two subcutaneous injections of cl. septicum bacterins were shown to provide resistance against intramuscular spore challenge. protection in mice, hamsters and guinea pigs was generally at low levels, in the range of 1 to 5 ld50. efficacy estimates, at these levels of challenge, indicated that a degree of relati ... | 1976 | 1001825 |
| deoxyribonucleases and hyaluronidases of clostridium septicum and clostridium chauvoei. iii. relationship between the two organisms. | 1976 | 940440 | |
| quantitative chemical analyses and antigenic properties of peptidoglycans from clostridium botulinum and other clostridia. | the cell wall peptodoglycans were isolated from clostridium botulinum and some other species of the genus clostridium by hot formamide extraction and their quantitative chemical composition and antigenic properties were determined. the petidoglycan of c. botulinum type e was found to be a diaminopimelic acid (dap)-containing type composed of glucosamine, muramic acid, glutamic acid, alanine and dap in the molar ratio of 0.76:0.78:1.00:1.88:0.81. all other types of c. botulinum and clostridium sp ... | 1976 | 62070 |
| clostridium septicum infection and antibiotic treatment in broiler chickens. | 1975 | 1114625 | |
| letter: clostridium septicum infection in chickens. | 1975 | 1114642 | |
| letter: an outbreak of gangrenous cellulitis caused by clostridium septicum in a broiler flock. | 1975 | 1164275 | |
| [bacteriocins of clostridium septicum (author's transl)]. | 17 strains of clostridium septicum were examined for bacteriocin production. two bacteriocin-producing strains were detected by the stab culture method and the spot test using the supernatant fluids of the cultures. the bacteriocin of cl. septicum ovinus was active against all other strains of cl. septicum without inhibiting the donro strain (table 2). this bacteriocin and one indicator strain (wex) were chosen for further study. the bacteriocin, which was spontaneously produced during the logar ... | 1975 | 1221680 |
| [effect of enterocin on clostridium perfringens and clostridium septicum (author's transl)]. | 1974 | 4152346 | |
| adenocarcinoma of the colon presenting as clostridium septicum cellulitis of the left thigh. | 1974 | 4834747 | |
| [non-traumatic infection with clostridium septicum]. | 1973 | 4741475 | |
| the deoxyribonucleases and hyaluronidases of clostridium septicum and cl. chauvoei. i. an agar plate method for testing for deoxyribonuclease. | 1972 | 5076438 | |
| the deoxyribonucleases and hyaluronidases of clostridium septicum and cl. chauvoei. ii. an agar plate method for testing for hyaluronidase. | 1972 | 5076439 | |
| [composition of the gases given off by clostridium septicum, clostridium chauvoei and welchia perfringens cultured in a sodium thioglycolate medium under vacuum after alkalinization of the medium at the end of cultivation]. | 1972 | 4338943 | |
| prevention of swarming of clostridium septicum. | 1972 | 4566879 | |
| letter: sudden deaths from clostridium septicum infection of the gobabis district. | 1972 | 4670770 | |
| [enterogenous non-traumatic gas phlegmon infection by clostridium septicum]. | 1971 | 4327293 | |
| [immunologic efficiency of clostridium septicum toxoid in the animal experiment]. | 1971 | 5147791 | |
| [study of the fine structure of spore formation in clostridium septicum]. | 1971 | 5131475 | |
| clostridium septicum infection of the thyroid gland. | 1970 | 5487765 | |
| [the in vitro identification and the in vivo action of clostridium septicum neuraminidase]. | 1970 | 5499382 | |
| glycolytic and related enzymes in clostridial classification. | the activities of 15 glycolytic and related enzymes were determined in clostridia. all contained 1-phosphofructokinase; three of them lacked 6-phosphofructokinase and mannitol 1-phosphate dehydrogenase. glucose 6-phosphate dehydrogenase was found in six clostridia, thus demonstrating the presence of hexose monophosphate shunt. only parts of the citric acid cycle were found to be present in most clostridia with an indication of the full cycle in clostridium septicum. the intermediary enzyme activ ... | 1969 | 4244302 |
| clostridium septicum and malignancy. | 1969 | 5819442 | |
| clostridium septicum infections and malignancy. | 1969 | 5819436 | |
| [comparative study of gases emitted by clostridium septicum and clostridium chauvoei cultivated on sodium thioglycolate medium]. | 1969 | 5373657 | |
| [clostridium septicum in a derby eland]. | 1969 | 5408497 | |
| sequential growth of clostridium chauvoei, clostridium septicum, and clostridium novyi in the same medium. | 1969 | 5782565 | |
| case report--clostridium septicum infection in a broiler flock. | 1969 | 5813245 | |
| on the growth and survival of clostridium septicum in soil. | 1969 | 4904967 | |
| direct-challenge potency test for bacterins containing clostridium septicum. | 1968 | 5637928 | |
| temperature studies on chicken inoculations to aid differentiation between clostridium chauvoei and clostridium septicum. | 1968 | 5655004 | |
| the relationship of the neuraminidase of clostridium septicum to the haemagglutinin and other soluble products of the organism. | 1968 | 5667846 | |
| the nature and properties of the haemagglutinin of clostridium septicum. | 1967 | 6029762 | |
| location of esterases in clostridium septicum and clostridium chauvoei: an electron microscope study. | 1967 | 5607845 | |
| [detection of clostridium septicum and cl. oedematiens by the fluorescent antibody technic]. | 1967 | 4899155 | |
| [composition of gases freed by clostridium sporogenes and by clostridium septicum cultivated in thioglycolate media]. | 1966 | 4958636 | |
| [composition of the gases liberated by clostridium septicum cultivated in a thioglycolate medium]. | 1965 | 4954598 | |
| [problems of obtaining toxin from clostridium septicum cultures]. | 1965 | 5833338 | |
| [a triggering factor in clostridium septicum gas gangrene]. | 1964 | 14137371 | |
| sucrose-fermenting strains of clostridium septicum. | 1963 | 14076707 | |
| [on liver lipids in guinea pigs. 3. the total lipid, neutral fat, phosphatide, cholesterol, fat-free dry substance and water content of the liver in clostridium septicum-infected guinea pigs]. | 1963 | 14107836 | |
| differentiation of clostridium septicum and clostridium chauvoei by the use of fluorescent labelled antibodies. | 1963 | 13966870 | |
| the interactions between clostridium septicum and clostridium histolyticum toxins and antitoxins. | 1962 | 13983973 | |
| [experimental inoculation of the chick embryo with clostridium septicum]. | 1962 | 14491667 | |
| [acetone purification of vibrio septicus anatoxin]. | 1959 | 13636339 | |
| [chick embryo as an object for the determination of vibrio septicus virulence]. | 1959 | 13636345 | |
| antigenic formulae for clostridium septicum and clostridium chauvoei. | 1959 | 13642182 | |
| [study of immunological phenomena by means of tissue culture. v. cytopathogenic effects of clostridium septicum toxin]. | 1959 | 13658454 | |
| [adsorption and elution of an active protein in vibrio septicus anatoxin]. | 1959 | 13671024 | |
| [anatoxin from vibrio septicus and its antigenic and immunogenic properties]. | 1958 | 13570447 | |
| complexity of toxins from clostridium septicum and clostridium chauvoei. | 1958 | 13598715 | |
| mixed bacterial infections in relation to antibiotic activities. ii. the role of staphylococcal antibiotic in a clostridium septicum-staphylococcus albus infection. | 1957 | 24544423 | |
| [bovine enzootic fulminating necrotic hepatitis due to association of welchia perfingens and clostridium septicum]. | 1956 | 13317177 | |
| [symptomatic anthrax of the face due to vibrio septicus]. | 1954 | 13145545 | |
| [new researches on the evaluation of the anti-histolyticum and anti-septicum activity of different sera]. | 1954 | 13158926 | |
| mixed bacterial infections in relation to antibiotic activities. i. clostridium septicum-micrococcus infections. | 1954 | 13201758 | |
| the effect of antibiotics on spores of clostridium septicum in vivo. | 1954 | 24543102 | |
| [antigens common to the toxins of clostridium septicum and histolyticum]. | 1953 | 13033375 | |
| [studies on the properties of clostridium histolyticum and clostridium septicum antisera]. | 1953 | 13124941 | |
| the survival of bacterial spores in arsphenamines. | 1952 | 14946683 | |
| effect of sub-lethal body x-radiation on susceptibility of mice to clostridium septicum toxin. | 1952 | 12983374 | |
| antibiotic prophylaxis of experimental clostridial infections. ii. penicillin prophylaxis of clostridium perfringens and clostridium septicum infections. | 1952 | 24542145 | |
| the beta-toxin (deoxyribonuclease) of cl. septicum. | 1951 | 14851168 | |
| studies on agglutination of red cells by clostridia. i. cl. septique. | 1951 | 14895790 | |
| the growth of clostridium septicum and its inhibition. | 1947 | 16561290 | |
| case report of sudden death [multiple clostridium septicum emboli in intrahepatic portal veins, with extensive necrosis of the liver]. | 1947 | 18906905 |