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in vitro antimicrobial activity of econazole and miconazole sulfosalicylate.the in vitro activities of new sulfosalicylic salts of econazole (e.ssa) and miconazole (m.ssa) have been investigated in comparison with the respective nitrate (nit) salts and sulfosalicylic acid (ssa) alone. the results reveal good antimicrobial activity of m.ssa and e.ssa against different strains of candida, dermatophytes, moulds, gram-positive bacteria and trichomonas vaginalis. the mic values demonstrate that m.ssa is more active than m.nit on candida and t. vaginalis. e.ssa was also more ...19902127740
separation of antibiotics by autofocusing.the autofocusing separation of nine antibiotics was investigated: tetracycline and chloramphenicol in large-scale batches, and seven others in gram preparation amounts. all except one were found to be heterogeneous in autofocusing, and 2-4 well-characterized fractions emerged. these heterogeneities are described and the industrial utilization of the procedure is suggested.19902127743
comparison of the antimicrobial effectiveness of regular and fresh scent clorox.the antimicrobial properties of two different compositions of sodium hypochlorite were compared in a tube dilution study. absorbent paper points were contaminated with streptococcus faecalis or candida albicans and exposed to 5.25% or 2.62% concentrations of "regular" or "fresh scent" sodium hypochlorite (clorox) for periods ranging from 15 to 120 s. the points were then removed from the sodium hypochlorite solution, placed into a growth medium, incubated, and the presence or absence of growth r ...19902127941
[sensitivity of clinical bacterial strains to ofloxacin]. 19902128121
microbiological study of enterococcus faecium sf68: post-antibiotic effect and growth curves.we studied the microbiological characteristics of enterococcus faecium sf 68 (an oral vaccine) assessing post-antibiotic effect of ampicillin and growth curves in different media. results showed a good resistance of the microorganism tested which has important implications in clinical practice. the growth ability of enterococcus faecium sf 68 was similar on all media tested.19902128365
importance of the aminoglycoside dosing regimen in the penicillin-netilmicin combination for treatment of enterococcus faecalis-induced experimental endocarditis.the penicillin-aminoglycoside combination is recommended for the treatment of systemic enterococcal infections. however, the optimal dosing regimen of the aminoglycoside remains to be elucidated. we evaluated the efficacy of penicillin, alone or in combination with various dosing regimens of netilmicin, for the treatment of experimental left-sided enterococcus faecalis endocarditis in rabbits. animals were injected intramuscularly for 4 days with penicillin alone or in combination with netilmici ...19902128443
[use of cefoperazone in patients after kidney transplantation]. 19902128960
nucleotide sequence of the sex pheromone inhibitor (iad1) determinant of enterococcus faecalis conjugative plasmid pad1.the determinant for the peptide sex pheromone inhibitor iad1 (iad) on the hemolysin/bacteriocin plasmid pad1 of enterococcus faecalis was sequenced. the sequence reveals a 22-amino-acid precursor with the carboxyl-terminal 8 residues corresponding to iad1. it appears that iad1 is a component of its own signal sequence.19902128961
high-level resistance to aminoglycosides in enterococci; incidence and alternative active antibiotic combinations in vitro.enterococci with high-level resistance to aminoglycosides have been frequently isolated from clinical specimens in the last few years. it is well known that this resistance is linked to a lack of synergism of the beta-lactam/aminoglycoside combination used in the treatment of severe infections. many authors have reported an increasing incidence of isolation of enterococci highly resistant to gentamicin. in order to overcome the failure of the currently used antimicrobial combinations, in this wo ...19902129028
radio-immunoassay for formyl methionyl leucyl phenylalanine. i. development and application to assessment of chemotactic peptide production by enteric bacteria.bacterial chemotactic peptides are low molecular weight peptides which stimulate a wide range of neutrophil functions following binding to specific leucocyte receptors. formyl methionyl leucyl phenylalanine (fmlp) is the major chemotactic peptide in escherichia coli culture supernatants. this paper reports the development and validation of a radio-immunoassay (ria) for fmlp and its application to the analysis of formyl peptide production by enteric bacteria in vitro. the assay was moderately sen ...19902129421
is candidiasis the true cause of vulvovaginal irritation in women with diabetes mellitus?vulvovaginitis is common in diabetic women and is often treated with antifungal agents on the assumption that the causative organism is candida albicans. in a survey of 100 consecutive diabetic women attending a diabetes clinic 36 had complained to their general practitioner about vulvovaginal irritation during the past three years and 26 were treated with antifungal agents without a vaginal examination or swabs being taken. in a separate study 27 post-menopausal women with non-insulin dependent ...19902131794
disinfection by endodontic irrigants and dressings of experimentally infected dentinal tubules.the effect of endodontic irrigants and dressings was tested on bacteria in bovine dentin specimens experimentally infected with enterococcus faecalis, streptococcus sanguis, escherichia coli, or pseudomonas aeruginosa. standardized, cylindrical dentin test pieces were prepared and cleaned by ultrasonic treatment with edta and sodium hypochlorite. the specimens were infected with the test organism for periods up to 14 days, and the degree of infection into the tubules was monitored using brown & ...19902133305
amplification of the na+-atpase of streptococcus faecalis at alkaline ph.the na+-atpase activity of streptococcus faecalis was influenced by the medium ph. activities of the protonophore-resistant na+ extrusion and the ktrii (active k+ uptake by the na+-atpase) were maximal in the cells grown at ph 9.5, and were minimal in those grown at ph 6.0. in the cells grown at ph 7.5, they were moderately observed. the na+-stimulated atpase activity of the cells grown at ph 9.5 was about 4-fold higher than that of the cells grown at ph 6.0. thus, amplification of the na+-atpas ...19902137787
mutants of streptococcus faecalis sensitive to alkaline ph lack na(+)-atpase.alkali-sensitive mutants which grow at ph 7.5 but not at ph 9.5 in na(+)-rich media were isolated from streptococcus faecalis atcc 9790. one of the mutants, designated nak1, lacked activities of both na(+)-stimulated atpase and ktrii (active k+ uptake by sodium atpase). these activities were restored in a spontaneous revertant designated nak1r. active sodium extrusion from nak1 was observed at ph 7.0, which allows the cells to generate a proton potential, but not at ph 9.5, which reverses the pr ...19902138604
mechanism of resistance to vancomycin in enterococcus faecium d366 and enterococcus faecalis a256.the role of the glycopeptide-inducible proteins of enterococcus faecium d366 (39.5 kilodaltons) and enterococcus faecalis a256 (39 kilodaltons) in the mechanism of resistance to vancomycin and teicoplanin was examined. crude cell walls from noninduced cells or from induced cells treated with sodium dodecyl sulfate to remove the inducible proteins were shown to bind vancomycin, in contrast to cell walls containing the cytoplasmic membrane-associated induced proteins, which did not bind vancomycin ...19902139314
in-vitro studies with ramoplanin (mdl 62,198): a novel lipoglycopeptide antimicrobial.ramoplanin is a novel lipoglycopeptide antimicrobial complex, isolated from the fermentation products of a strain of actinoplanes sp. (atcc 33076), which comprises three closely related polypeptides, each containing chlorinated phenyl moieties and d-mannose. the in-vitro activity of ramoplanin was compared with those of vancomycin and teicoplanin. ramoplanin was very active against staphylococcus spp., irrespective of methicillin susceptibility, with all isolates inhibited by 1 mg/l or less. con ...19902139436
[the distribution of and methods for detecting pseudomonas aeruginosa in mineral waters].the value of different methods of p. aeruginosa identification in mineral water has been studied and compared. natural studies indicate great contamination of balneological technical systems with p. aeruginosa.19902139997
treatment of bone and soft tissue infections with teicoplanin.the use of teicoplanin was evaluated in a group of 33 patients, which included 18 prosthetic infections, seven with osteomyelitis, five skin and soft tissue infections, and three cases of septic arthritis. the bacterial pathogens isolated were 27 isolates of staphylococcus aureus (methicillin sensitive 18; methicillin resistant 9), staph. hominis (2), staph. epidermidis (1), staph. haemolyticus (2), enterococcus faecalis (1), streptococcus pyogenes (1), peptococcus spp. (1). eleven patients had ...19902140111
[significance of fecal streptococci in the detection of bacteriologic contamination of drinking water].because of their increased environmental resistance faecal streptococci are a good indicator of a contamination dating back a long time. under the new federal german drinking water regulations, examination of faecal streptococci is not mandatory. on the basis of 190 samples of water from natural springs it was shown that, if the water was examined only in respect of e. coli and coliform bacteria there were no objections in 22% of water that was faecally contaminated, so that such water escaped d ...19902141396
efficacy of teicoplanin in two dosage regimens for experimental endocarditis caused by a beta-lactamase-producing strain of enterococcus faecalis with high-level resistance to gentamicin.optimal therapy for the treatment of infections caused by strains of enterococci demonstrating high-level resistance to gentamicin and other aminoglycosides has not been established. the present study examined the efficacy of teicoplanin, a glycopeptide antibiotic active against gram-positive bacterial infections in various animal models, in the treatment of experimental endocarditis due to a beta-lactamase-producing strain of enterococcus faecalis with high-level resistance to gentamicin. vanco ...19902141778
the activity in vitro of trospectomycin sulphate (u-63366f) against aminoglycoside-resistant enterococci.trospectomycin (u-63366f), a 6'-propyl analogue of spectinomycin, was tested against aminoglycoside-resistant enterococci. the mic90 for enterococcus faecalis was 4 mg/l and that for e. faecium was 8 mg/l. trospectomycin alone was not bactericidal for enterococci, with mbc90 4096 mg/l for both e. faecalis and e. faecium. the addition of commercially available polyvalent immunoglobulin decreased significantly both the mics and the mbcs and the rendered trospectomycin bactericidal for enterococci. ...19902142683
in-vitro comparison of the post-antibiotic effect of vancomycin and teicoplanin.the post-antibiotic effect (pae) of teicoplanin was compared with that of vancomycin for five selected gram-positive cocci. two concentrations of each antibiotic were investigated, with the test organisms being exposed to each for both 1 and 2 h. at a concentration of 25 mg/l, teicoplanin had a greater pae than vancomycin for the methicillin resistant staphylococci and enterococcus faecalis strains tested. at a concentration of 5 mg/l, teicoplanin gave equal effects to those of vancomycin except ...19902145256
release of the component of streptococcus faecalis na(+)-atpase from the membranes.the na(+)-stimulated atpase activity of streptococcus faecalis was lost by washing the membranes with ethylenediaminetetraacetic acid (edta). atpase activities of both the edta extract and the stripped membranes did not show any stimulation by na+ ions. however, the na(+)-stimulated atpase was readily reconstituted by an incubation of these fractions combined. it was only reconstituted from the fractions prepared under the condition that the na(+)-atpase is amplified, and not from those boiled o ...19902146151
some features of the streptococcus faecalis na(+)-atpase resemble those of the vacuolar-type atpases.in the ethylenediaminetetraacetic acid (edta) extract prepared from the membranes of streptococcus faecalis, we found the 330-kda protein that was coordinately increased with the induction of na(+)-atpase. it was missed in the edta extract of nak1, a mutant defective in the na(+)-atpase, but restored in that of its revertant, nak1r. the 330-kda protein showed the atp hydrolytic activity by active staining, and mainly consisted of the polypeptides of 73 kda, 52 kda and possibly 38 kda. in additio ...19902146156
the role of escherichia coli haemolysin in the pathogenic synergy of colonic bacteria in subcutaneous abscess formation in mice.the growth of nine species of colonic bacteria--escherichia coli, enterococcus faecalis, bacteroides ovatus, fusobacterium varium, clostridium perfringens, klebsiella pneumoniae, proteus vulgaris, staphylococcus aureus and bifidobacterium adolescentis--was examined after concomitant injection to form experimental subcutaneous abscesses in mice. injection of a mixture of c. 10(5) cfu of each of the first five strains (e. coli, ent. faecalis, b. ovatis, f. varium and c. perfringens) resulted in ab ...19902146395
role of bacteroides uniformis in susceptibility of ta:cf# 1 mice to infection by treponema hyodysenteriae.among the various strains and colonies of mice tested specific-pathogen-free (spf) ta:cf#1 mice exhibited the highest susceptibility to treponema hyodysenteriae infection. staphylococcus epidermidis 1047, streptococcus faecalis 2039, lactobacillus murinus 3010, escherichia coli 1049, and bacteroides thetaiotaomicron 3008 were administered to the ta:cf#1 mice. b. uniformis ik, which appeared to colonize in the breeding facility under spf conditions, was isolated from the cecal content of a ta:cf# ...19902148089
a randomized prospective study of ceftazidime and ciprofloxacin with or without teicoplanin as an empiric antibiotic regimen for febrile neutropenic patients.febrile neutropenic patients were randomized to receive ceftazidime and ciprofloxacin with the addition of teicoplanin in cases with clinical suspicion of a hickman line-associated infection. at 48 h both clinical and bacteriological analyses were made. patients were categorized as: success, in cases of improvement or stability in the clinical condition; failure, if there was a deterioration of the clinical condition; and non-evaluable, in cases of protocol violation or death due to other causes ...19902149051
in vitro activity of ly264826, a new glycopeptide antibiotic, against gram-positive bacteria isolated from patients with cancer.the in vitro activity of ly264826, a novel glycopeptide antibiotic produced by amycolatopsis orientalis, was compared with those of vancomycin, teicoplanin, and oxacillin against 311 gram-positive clinical isolates from patients with cancer, ly264826 had lower mics for 90% of isolates (mic90) than vancomycin for all species tested. it was active against oxacillin-resistant isolates including staphylococcus aureus (mic90, 0.5 micrograms/ml), staphylococcus haemolyticus (mic90, 2.0 micrograms/ml), ...19902149921
[regulatory mechanism of the cytoplasmic ph by h(+)-adenosinetriphosphatase].nature prefers simplicity. streptococcal cytoplasmic ph is regulated in a simple biological manner: change in the amount of the adenosinetriphosphatase (h(+)-atpase). this enzyme is identical to the f0f1-complex of oxidative phosphorylation, which synthesizes adenosinetriphosphate in mitochondria and most of bacteria, whereas it is used as a regulator of the cytoplasmic ph in streptococci which have no respiratory chain. eukaryotes use the another type of h(+)-atpase to regulate the internal ph. ...19902150080
comparative kinetics of hematoporphyrin derivative uptake and susceptibility of bacillus subtilis and streptococcus faecalis to photodynamic action.hematoporphyrin derivative (hpd) is widely used in photoradiation therapy of tumors and other diseases, and has been shown to affect the viability of gram positive bacteria. this investigation assessed the efficiency of binding of hpd to bacillus subtilis and streptococcus faecalis when hpd-treated organisms were exposed to red light. kinetic studies indicated that the amount of hpd bound increased with increasing external concentration of hpd until saturation of binding sites was reached. s. fa ...19902150982
[relation between the processes of water self-purification and the level of microbial pollution in the southern regions of the rsfsr].it has been found out as result of complex sanitary-hygienic, microbiological and statistical studies, that the intensity of processes of self-purification of the water in water objects form potentially pathogenic microflora is reduced under the im fluence of the increasing anthropogenic stress on the water bodies in the southern area which can produce unfavourable human health effects. the necessity that a complex of sanitary-microbiological indicators of water quality should be used to provide ...19902151191
[spontaneous tumor regression in a patient with metastatic gastric cancer. communication of an additional case].a new case of spontaneous tumor regression in a patient with a metastatic gastric carcinoma, associated to an infectious abscess in the abdominal wall is presented. streptococcus faecalis and staphylococcus aureus were isolated in the abscess. this interesting case is the third patient that fulfils spontaneous regression criteria associated to infection identified at the university clinic of navarra.19902151656
genetic analysis of the pad1 hemolysin/bacteriocin determinant in enterococcus faecalis: tn917 insertional mutagenesis and cloning.thirty-seven nonhemolytic/nonbacteriocinogenic mutations in enterococcus (streptococcus) faecalis plasmid pad1 were generated by tn917 insertion. all were found to belong to one of two complementation classes. each class of mutants secreted either hemolysin/bacteriocin (hly/bac) component a or l into the culture medium. dna encoding hly/bac was cloned in escherichia coli in which both components of the hemolysin were expressed individually and collectively. the region encoding components a and l ...19902152897
comparison of enterococcal and staphylococcal beta-lactamase plasmids.in staphylococcus aureus, beta-lactamase (bla) is typically associated with transducible plasmids that also encode metal resistance or with the more recently described conjugative, gentamicin resistance plasmids. the beta-lactamase gene of enterococcus faecalis, which has been shown to be highly homologous to bla from the s. aureus plasmid p1258, is also encoded on conjugative, gentamicin resistance plasmids. to determine if the enterococcal bla-encoding plasmids are similar to those from staphy ...19902153187
stimulation of oxidative burst in human monocytes by lipoteichoic acids.lipoteichoic acid isolated from streptococcus faecalis or streptococcus pyogenes caused direct activation of the respiratory burst in human peripheral blood monocytes. this activity appears to be related to the ability of lipoteichoic acid to bind to the monocyte membrane and trigger the polarization of receptors (capping).19902153634
movable genetic elements and antibiotic resistance in enterococci.the enterococci possess genetic elements able to move from one strain to another via conjugation. certain enterococcal plasmids exhibit a broad host range among gram-positive bacteria, but only when matings are performed on solid surfaces. other plasmids are more specific to enterococci, transfer efficiently in broth, and encode a response to recipient-produced sex pheromones. transmissible non-plasmid elements, the conjugative transposons, are widespread among the enterococci and determine thei ...19902156704
stimulation of the respiratory burst in peripheral blood monocytes by lipoteichoic acid. the involvement of calcium ions and phospholipase a2.lipoteichoic acid (lta) from streptococcus faecalis stimulates the respiratory burst in peripheral blood monocytes (mon), as measured by cytochrome c reduction. the effect of lta was time and dose dependent. lta stimulated the respiratory burst in a biphasic manner within a range of 1 to 1000 ng/ml.10(6) mon, with maximal activity at 50 ng/ml. at this concentration lta increased the activity from 0.97 +/- 0.2 to 4.88 +/- 0.2 nmol.10(6) mon/20 min. the role of calcium ions in the effect of lta in ...19902156929
transfer and expression of the tetracycline resistance transposon tn925 in acetobacterium woodii.the enterococcus faecalis conjugative plasmid pcf10 was used to introduce tn925 into acetobacterium woodii by filter mating. tetracycline resistance was transferred at frequencies of about 10(-6) per donor, but no plasmid dna was found in the transconjugants. dna hybridization analyses of hindiii-digested chromosomal dna demonstrated the insertion of tn925 at a variety of locations, whereas wild type dna showed no hybridization at all. the transconjugants were used as donor in mating experiments ...19902158923
regulation of the pad1 sex pheromone response in enterococcus faecalis: effects of host strain and traa, trab, and c region mutants on expression of an e region pheromone-inducible lacz fusion.pheromone-induced conjugal transfer of the hemolysin-bacteriocin plasmid pad1 of enterococcus faecalis is regulated by a cluster of determinants designated traa, trab, and regions c and e. the e region is believed to include a positive regulator that controls many structural genes related to conjugation. the pheromone-inducible tn917-lac fusion nr5, located in the e region, is regulated by the products of traa, trab, and the c region. to more closely examine the effects of these genes on the ind ...19902158976
in vitro activity of daptomycin-metronidazole combinations against mixed bacterial cultures: reduced activity of metronidazole against bacteroides species in the presence of enterococcus faecalis.the in vitro activity of daptomycin-metronidazole combinations against mixed cultures of gram-positive facultative cocci and strains of the bacteroides fragilis group was investigated. metronidazole did not influence the high activity of daptomycin against strains of staphylococcus aureus, staphylococcus epidermidis and enterococcus faecalis in the absence or presence of the co-cultured bacteroides strains. in contrast, the enterococcus faecalis isolates protected the co-cultured bacteroides str ...19902161762
heterogeneity among the flavin-containing nadh peroxidases of group d streptococci. analysis of the enzyme from streptococcus faecalis atcc 9790.polyclonal antisera prepared against the purified nadh peroxidase from streptococcus faecalis atcc 9790 (enterococcus hirae) do not cross-react with the atcc 11700 enzyme. comparative tryptic maps of the two proteins indicate that the differences in primary structures extend beyond those localized to respective antigenic epitopes. alignments of the nh2-terminal and active-site cysteinyl peptide sequences of the two streptococcal peroxidases reveal identities of 50 and 67% in the respective overl ...19902161844
effect of human serum on the bactericidal activity of daptomycin and vancomycin against staphylococcal and enterococcal isolates as determined by time-kill kinetic studies.the bactericidal activity of daptomycin and vancomycin alone in cation-supplemented mueller-hinton broth and in human serum against clinical isolates of staphylococcus aureus, staphylococcus epidermidis, and enterococcus faecalis was evaluated by exposing replicating microorganisms to concentrations ranging from 2 to 128 micrograms/ml for 24 hr. in addition, the possibility of emergence of resistance, the stability of each agent in the respective medium, and the percent of protein binding by hum ...19902166634
in vitro response to bactericidal activity of cell wall-active antibiotics does not support the general opinion that enterococci are naturally tolerant to these antibiotics.the incidence of tolerance and paradoxical response to bactericidal activity of penicillin was investigated in 50 clinical isolates of enterococcus faecalis. of the isolates tested, 86% exhibited the paradoxical phenomenon whereby there were more survivors at high than at low concentrations above the mic. low penicillin concentrations caused decreases equal to or higher than 99.9% in 11 strains, from 99.9 to 99.5% in 23 strains, and lower than 99.5% in 9 strains. of the total strains, 14% were k ...19902171422
nucleotide sequence of the tet(m) gene of tn916. 19902172929
tn3702, a conjugative transposon in enterococcus faecalis.enterococcus faecalis strain d434 was found to carry on its chromosome a determinant encoding tetracycline-minocycline resistance (tcr-mnr) and to harbor both an r plasmid and a cryptic conjugative plasmid, pip1141. the determinant coding for tcr-mnr was located on a conjugative transposon, designated tn3702. the transposition of tn3702 on to both pip1141 and the hemolysin plasmid pip964 yielded different derivatives each of which contained an 18.5-kilobase insert. the structure of tn3702 is sim ...19902178139
transferable tet m in fusobacterium nucleatum.two tetracycline-resistant fusobacterium nucleatum strains were able to transfer, by conjugation, tetracycline resistance and the tet m determinant to recipient f. nucleatum, peptostreptococcus anaerobius, and enterococcus faecalis strains at a frequency of 10(-1) to 10(-8).19902178339
mechanisms of resistance of enterococci to beta-lactam antibiotics.two mechanisms are responsible for resistance of enterococci to beta-lactam antibiotics: alterations of penicillin-binding proteins and production of a beta-lactamase. the latter has been found in a few clinical isolates of enterococcus faecalis, whereas the former appears to account for resistance in most strains. a correlation has been established between the amount of a particular penicillin-binding protein which has a low affinity for penicillin and the level of resistance. the higher activi ...19902180705
ampicillin/sulbactam versus clindamycin in the treatment of postpartum endomyometritis.sixty-eight patients with postpartum endomyometritis were enrolled in this open randomized comparative study. forty-two patients received ampicillin/sulbactam and 26 received clindamycin. the cure rates were similar in the two groups: 83% in the ampicillin/sulbactam group and 88% in the clindamycin group. the most frequent endometrial bacterial isolates were bacteroides bivius, streptococcus faecalis, escherichia coli, and ureaplasma urealyticum. bacteremia was present in 15 of 68 (22%), the mos ...19902181689
viability of salmonella spp and indicator microorganisms in seawater using membrane diffusion chambers.diffusion chambers with polycarbonate membrane-filter side walls were used to study the comparative survival of fecal indicators (escherichia coli and streptococcus faecalis) and enteric pathogens (salmonella enteritidis, s. postdam, s. typhimurium, s. london and s. infantis) in natural seawater. it was observed that the percentages of sublethal injury increased with exposure to the marine environment, and that these environmental injuries depended on the microorganism considered. a large propor ...19902181926
coaggregation of streptococcus sanguis and other streptococci with candida albicans.thirteen strains of viridans group streptococci and two strains of other streptococci were tested for coaggregation with candida albicans. streptococcus sanguis strains generally exhibited low levels of adherence to 28 degrees c-grown exponential-phase yeast cells, but starvation of yeast cells for glucose at 37 degrees c (or at 28 degrees c) increased their coaggregating activity with these streptococci by at least tenfold. this was a property common to four c. albicans strains tested, two of w ...19902182544
antibiotic prophylaxis: is there a difference?seven antibiotics, administered in 10 different regimens for prophylaxis, were randomly assigned to 1580 patients who were delivered by cesarean section. cefazolin 1 gm, administered for three doses, served as the control group. cefazolin 1 gm, cefazolin 2 gm, cefoxitin 1 gm, cefoxitin 2 gm, cefonicid 1 gm, cefotetan 1 gm, ceftizoxime 1 gm, ampicillin 2 gm, and piperacillin 4 gm were all administered in a single dose. four antibiotics proved to be superior in preventing postpartum endometritis: ...19902183617
therapeutic effects of cefpirome, a new cephalosporin, on various models of infections in mice and rats.cefpirome (hr 810) is a new cephalosporin with a 2,3-cyclopentenopyridine group in the 3-position side chain. it was compared with other cephem antibiotics in protective and therapeutic effects on various experimental infections, systemic and local, in mice and rats. hr 810 had more potent protective effect than ceftazidime (caz), cefoperazone (cpz), and cefotaxime (ctx) on systemic infections induced by escherichia coli ec-31, staphylococcus aureus smith, and serratia marcescens sm-6 in mice. a ...19902190011
therapeutic effects of cefpirome (hr 810) on experimental mixed infections with enterococcus faecalis and escherichia coli in mice.the therapeutic effects of cefpirome (hr 810), a new cephalosporin, on mixed infections induced in mice with enterococcus faecalis hl1147 and escherichia coli hl34 were compared with those of ampicillin (amp), cefuzonam (czon), and ceftazidime (caz). cefpirome was more effective in protecting mice with systemic mixed infection (median effective dose, 52 mg/kg) than the other antibiotics (all more than 320 mg/kg). with increasing doses of cefpirome, the percentages of the animals having e. faecal ...19902194972
incidence and significance of intraperitoneal aerobic and anaerobic bacteria.intra-abdominal infections frequently occur after trauma, surgical resections, or intrinsic diseases of the gastrointestinal tract. these infections, which can be generalized or localized in intraperitoneal or extraperitoneal locations as well as in organs, are often difficult to diagnose and treat. they are usually polymicrobial, involving both aerobic and anaerobic bacteria. the average number of bacterial strains recovered is between two and five, with anaerobes dominating. the aerobic microo ...19902196123
conjugative plasmid transfer from escherichia coli to clostridium acetobutylicum.the conjugation mechanism of incp plasmids may be employed to mobilize small non-conjugative plasmids from escherichia coli to a wide range of different organisms. this strategy has been adapted for use with the gram-positive anaerobe, clostridium acetobutylicum ncib 8052. several shuttle vectors containing replicons from pam beta 1 (enterococcus faecalis), pcb101 (clostridium butyricum) or pwv01 (streptococcus cremoris), together with the cis-acting orit region of rk2, have been constructed, an ...19902199603
high-level chromosomal gentamicin resistance in streptococcus agalactiae (group b).this is the first report of high-level gentamicin resistance in a group b streptococcus. strain b128 of serotype ii was isolated from an infected leg wound in 1987. b128 was resistant to high levels of gentamicin as well as of all other available aminoglycosides and was also resistant to tetracyclines. no bactericidal synergism was found between ampicillin or vancomycin and any of these aminoglycosides. gentamicin, kanamycin, streptomycin, and tetracycline resistance determinants transferred by ...19902203311
in vitro activity of pd127,391, a new quinolone against bacterial isolates from cancer patients.the in vitro activity of pd127,391, a new 4-quinolone, was compared to that of ciprofloxacin against common clinical bacterial isolates from patients with cancer. pd127,391 was found to have a broad antimicrobial spectrum with excellent activity against gram-positive isolates (including multidrug-resistant organism such as corynebacterium jeikeium, enterococcus faecalis, enterococcus faecium, methicillin-resistant staphylococcus aureus and coagulase-negative staphylococcus spp.). it was also ext ...19902209169
nosocomial infections in general surgery: surveillance report from a german university clinic.at the general surgery clinics, university of giessen, we developed our own system for surveillance of nosocomial infections according to the guidelines of the centers of disease control. atlanta, usa, and according to the results of the senic project. we wanted to receive information about the overall infection rate, the procedure specific infection rate, site specific infection rate, distribution of nosocomial infections by pathogen and resistance pattern of antibiotics at the general surgery ...19902210853
[prevalence of nosocomial infections in catalonia. ii. microorganisms and antimicrobial agents].in the prevalence study of infections carried out in 33 hospitals from catalonia in 1988, where 7,434 patients were included, information about the responsible microorganisms and the prescribed antimicrobials was collected (in addition to the data on community and hospital infections and risk factors) and is reported in the present article. the microbiological diagnosis was made in 43% of hospital infections and in 31.9% of community infections. gram negative organisms predominated (57.3% of iso ...19902214904
synthesis and antimicrobial activities of some new tetrahydro-2h-1,3,5-thiadiazine-2-thione derivatives of amoxicillin.a number of 6-[2-(dihydro-5-substituted-6-thioxo-2h-1,3,5-thiadiazine-3( 4h)-yl)-2-(4-hydroxyphenyl)acetamido]penicillanic acids has been synthesized as prodrugs by incorporating the amine group of amoxicillin trihydrate into tetrahydro-2h-1,3,5-thiadiazine-2-thione ring. the compounds have been prepared by the reaction of various alkyl or aralkyl amines with potassium hydroxide, carbon disulfide, formaldehyde and amoxicillin trihydrate. the structures of the compounds have been elucidated by uv ...19902222554
[comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1987). ii. background of patients].in the retrospective survey of the sensitivity of clinical isolates reported in this journal, patients' backgrounds were also investigated. some findings are summarized below. 1. age distribution by sex: patients with ages 50 years and older accounted for a majority, irrespective of their sexes amounting 67.6% for both sexes combined. 2. annual distribution of sexes by age group: females accounted for a majority in younger age brackets, but the proportion of males increased with age, accounting ...19902232149
effect of pefloxacin on microorganism: host cell interaction.recent evidence indicates that certain antibiotics affect bacterial adherence and phagocyte-micro-organism interactions. these interactions are important in the early stages of bacterial pathogenesis, that is, attachment to mucosal surfaces and invasion. among the antibiotics of interest in this field are the fluoroquinolones. sub-mics of pefloxacin can alter the ability of gram-positive cocci (staphylococcus aureus, enterococcus faecalis) and gram-negative bacilli (escherichia coli) to adhere t ...19902258345
comparative in vitro activity of the new oral cephalosporin bay v 3522 against aerobic and anaerobic bacteria.the in vitro activity of the new oral cephalosporin bay v 3522 against 229 aerobic and 330 anaerobic clinical isolates was determined using the agar dilution technique. for comparison, amoxicillin, amoxicillin/clavulanate, cefaclor, cefadroxil, cefuroxime, cephalexin, ciprofloxacin, clindamycin, co-trimoxazole, doxycycline, erythromycin and metronidazole (only anaerobic bacteria) were tested. bay v 3522 was found to have high activity against staphylococcus aureus, staphylococcus epidermidis, en ...19902261923
identification of lactococci and enterococci by colony hybridization with 23s rrna-targeted oligonucleotide probes.specific sequences of 23s rrna of lactococcus lactis, enterococcus faecalis, enteroccus faecium, and enterococcus malodoratus/enterococcus avium were identified, and complementary oligonucleotide probes were synthesized. the specificity of the probes was evaluated by dot blot and colony hybridizations. the probes can be used for the specific detection and identification of colonies of the corresponding species in mixed cultures.19902275539
identification of chromosomal antibiotic resistance genes in streptococcus anginosus ("s. milleri").determinants encoding resistance to antibiotics, except penicillin, of 5 of 21 streptococcus anginosus clinical isolates that we examined transferred by conjugation into enterococcus faecalis and into 1 to 5 streptococcal recipients at frequencies of 10(-6) to 10(-8) transconjugants per donor. no r plasmids were detected in any wild-type strain. dna homology was detected between chromosomal fragments and the following genes: aade in 7 strains that were highly resistant to streptomycin, aph-3 in ...19902285280
intravenous ofloxacin in severe infections.the efficacy and tolerance of intravenous ofloxacin was studied in 70 patients suffering from soft tissue infections (n = 33), intra-abdominal abscesses (n = 14), septicaemia (n = 12), pneumonia (n = 9) and brucellosis (n = 2). the average daily dose was 6 mg/kg divided into two doses. pathogens treated included enterobacter cloacae (n = 14), escherichia coli (n = 12), staphylococcus aureus (n = 13), pseudomonas aeruginosa (n = 11), klebsiella pneumoniae (n = 10), enterococcus faecalis (n = 8) a ...19902286587
[clinical study of s 6472 in urinary tract infection].clinical studies on s 6472, a longer lasting preparation of cefaclor (ccl), were performed and the following results were obtained. s 6472 was administered orally to 102 patients with urinary tract infections including 16 with acute uncomplicated pyelonephritis, 32 with acute uncomplicated cystitis, 31 with complicated pyelonephritis and 23 with complicated cystitis. 95 patients were treated with 375 mg of s 6472 2 times daily and 7 patients were treated with 750 mg of s 6472 2 times daily. the ...19902287054
[susceptibility of clinically isolated bacterial strains to imipenem/cilastatin sodium].in vitro antibacterial activities of imipenem/cilastatin sodium (imipenem) and other beta-lactams against clinically isolated 353 bacterial strains were investigated. the results obtained in this study are summarized as follows: 1. imipenem (ipm) showed potent antibacterial activities against gram-positive cocci such as staphylococcus aureus, staphylococcus epidermidis, enterococcus faecalis, streptococcus agalactiae. 2. ipm had inferior or equivalent antibacterial activities to beta-lactams aga ...19902287059
[susceptibilities of clinical bacterial isolates to antimicrobial agents. a study mainly focused on imipenem. reported by the research group for testing imipenem susceptibility on clinical isolates].this study was conducted to investigate susceptibilities of clinical bacterial isolates to imipenem (ipm) and other antibacterial agents at 64 hospital laboratories throughout japan from september to december of 1988. in this study, identification and susceptibility testing were carried out at each laboratory and the tests were performed according to the disk dilution method recommended by nccls in which susceptibilities are classified into "s", "ms", "i" and "r". ipm showed markedly high in vit ...19902287060
synthesis and antimicrobial activities of some new tetrahydro-2h-1,3,5-thiadiazine-2-thione derivatives of ampicillin.compounds having alpha-[dihydro-5-substituted 6-thioxo-2h- 1,3,5-thiadiazine-3(4h)-yl]benzylpenicillin structure were synthesized by the reaction of ampicillin trihydrate, formaldehyde and dithiocarbamic acid salts. the structures were evident from chemical and spectral analysis. the antimicrobial activities of the compounds were investigated against some gram-positive (staphylococcus aureus and streptococcus faecalis) and gram-negative (escherichia coli and pseudomonas aeruginosa) bacteria and ...19902288482
ciprofloxacin therapy of urinary tract infections in paraplegic and tetraplegic patients: a bacteriological assessment.the efficacy of a 250 mg dose of oral ciprofloxacin twice daily for five days was studied in the treatment of urinary tract infection in paraplegic and tetraplegic patients. thirty-eight patients completed the study. by day 3 of therapy the infecting organisms had been eradicated from the urine in 97.2% of the patients. follow-up, post-therapy samples on day 14 showed 66.7% positive culture results and by day 35, 92.0% were positive. the ciprofloxacin therapy proved efficacious in 97.2% of the p ...19902292539
azurocidin and a homologous serine protease from neutrophils. differential antimicrobial and proteolytic properties.two 29-kd polypeptides, azurocidin and p29b, were purified to homogeneity from human neutrophils by acid extraction of azurophil granule membrane-associated material followed by gel filtration and reverse-phase chromatography. azurocidin and p29b share nh2-terminal sequence homology with each other as well as with elastase, cathepsin g, and other serine proteases. p29b bound [3h]diisopropyl fluorophosphate and hydrolyzed elastin, casein, and hemoglobin. a peptide substrate for p29b could not be ...19902312733
enterococcal resistance to vancomycin and related cyclic glycopeptide antibiotics.enterococci belonging to various species resistant to vancomycin and related cyclic glycopeptide antibiotics have been isolated from hospitalized patients in france, the uk and the usa. all such strains examined display inducible synthesis of a membrane protein associated with resistance. the mechanism by which the membrane protein acts has not been definitively established, but it may block the access of the antibiotic to its peptidoglycan target. that the protein could be a bypass enzyme has n ...19902318215
effect of dietary components on the indigenous oral bacterial flora of balb/c mice.diet is recognized as one of the most important factors affecting the equilibrium of the oral bacterial flora. studies related to dental caries development have focused mainly on the effect of carbohydrates. in the present work, using swabbing coupled with an immuno-colony-blot assay, we followed the indigenous oral bacterial populations of balb/c mice fed diets with different concentrations of sucrose, starch, proteins, lipids, vitamins, and minerals for a period of 14 days. the results indicat ...19902324350
in vitro activity of ro 23-9424, a dual-action cephalosporin, compared with activities of other antibiotics.the in vitro activity of ro 23-9424, which is desacetyl-cefotaxime linked to fleroxacin, was compared with the activities of cefotaxime, desacetyl-cefotaxime, fleroxacin, ofloxacin, and ciprofloxacin. it inhibited the majority of members of the family enterobacteriaceae, except for some serratia marcescens, citrobacter freundii, and enterobacter cloacae strains, at less than or equal to 0.25 microgram/ml and had an mic for 90% of strains tested (mic90) of 8 micrograms/ml against pseudomonas aeru ...19902327765
genetic basis of tetracycline resistance in urogenital bacteria.the distributions of the nucleotide sequences related to the tetracycline resistance determinants tet k, tet l, tet m, and tet o were studied by dot blot hybridization with randomly chosen clinical urogenital tract isolates of viridans group streptococci, streptococcus agalactiae, enterococcus faecalis, gardnerella vaginalis, lactobacillus spp., fusobacterium nucleatum, peptostreptococcus spp., and veillonella parvula. among the peptostreptococcus spp., 79% of the isolates hybridized with one (6 ...19902327774
in vitro evaluation of win 57273, a new broad-spectrum fluoroquinolone.win 57273 is a new fluoroquinolone that has an expanded spectrum of activity against staphylococcus spp. (mic for 90% of isolates [mic90], 0.008 microgram/ml), enterococcus faecalis (mic90, 0.06 microgram/ml), bacillus spp. (mic90, 0.03 micrograms/ml), listeria monocytogenes (mic90, 0.06 microgram/ml), streptococcus spp. (mic90, 0.03 microgram/ml), and bacteroides fragilis group strains (mic90, 0.5 microgram/ml). like other fluoroquinolone compounds, win 57273 was active against members of the f ...19902327779
vancomycin resistance is encoded on a pheromone response plasmid in enterococcus faecium 228.in enterococcus faecium 228, vancomycin resistance is encoded on a 55-kilobase conjugative plasmid, phkk100. this plasmid was transferred with high frequency into susceptible strains of enterococcus faecalis and conferred responses to pheromones produced by e. faecalis and streptococcus sanguis. phkk100 is the first plasmid described that mediates both vancomycin resistance and pheromone response.19902327781
catheter-related right-sided endocarditis in bone marrow transplant recipients.bone marrow transplant recipients are at increased risk of severe central venous catheter-related septicemias that may be complicated by endocardial infection. in view of this, we prospectively evaluated 141 consecutive patients receiving allogeneic or autologous bone marrow infusion. seven (5%) of 141 patients developed eight episodes of a clinical syndrome compatible with catheter-related right-sided infective endocarditis; this diagnosis was confirmed at autopsy in two patients who died. stap ...19902330480
efficacy of sulbactam in an in vitro model of mixed aerobic/anaerobic infections.bacterial interactions in mixed infections may interfere with antimicrobial therapy. the in-vitro efficacy of ampicillin alone, combination sulbactam/ampicillin, and metronidazole was studied. strains of bacteroides fragilis, escherichia coli, and enterococcus faecalis, alone and in association, were tested by means of a broth dilution method. minimal bactericidal concentrations (mbc) of ampicillin for b. fragilis 74 in association with e. coli 68 were up to 16-fold higher than for b. fragilis 7 ...19902332245
nucleotide sequence of the fosb gene conferring fosfomycin resistance in staphylococcus epidermidis.we have determined the nucleotide sequence of gene fosb of plasmid pip1842, which confers resistant to fosfomycin in staphylococcus epidermidis bm2641. the resistance gene was identified as a coding sequence of 417 bases pairs corresponding to a protein with a calculated mw of 16,345 daltons. this value is in good agreement with that of 15,000, estimated by sds-polyacrylamide gel electrophoresis of a bacterial cell-free coupled transcription-translation system. the fosb gene product exhibits 48% ...19902341025
preparation of the bowel before elective surgery using a polyethylene glycol solution at home and in hospital compared with conventional preparation using magnesium sulphate.bowel preparation by conventional methods is time-consuming and unpleasant for both patient and staff. in addition, it requires admission to hospital several days before surgery. preparation using oral polyethylene glycol solution is more acceptable and can easily be adapted so that the patient can perform the procedure at home before admission to hospital. in a prospective series we have compared the efficacy of preparation at home using polyethylene glycol with similar preparation in hospital ...19902342002
[cefpiramide: antibacterial activity, pharmacokinetics, and clinical evaluation].we determined mic values of cefpiramide (cpm) against clinical isolates from 100 patients who were subjected to total hysterectomy between april 1986 and march 1988. we also investigated the concentrations of cpm in uterine tissue and assessed the clinical efficacy of postoperative prophylaxis. 1. against bacteria isolated from clinical materials the mic80 values of cpm were as follows: staphylococcus epidermidis 1.56 micrograms/ml, enterococcus faecalis 25 micrograms/ml, and escherichia coli 6. ...19902348553
effects of room-temperature exposure on bacterial growth in stored red cells.experiments were performed to determine the effect of room-temperature (rt) exposure on the growth rates of selected bacteria by deliberate contamination of as-1 packed red cell (rbc) units contained in pl146 plastic bags. isolates of staphylococcus aureus, s. epidermidis, streptococcus faecalis, pseudomonas aeruginosa, citrobacter freundii, enterobacter agglomerans, and yersinia enterocolitica were inoculated into 3- to 5-day-old packed rbc units. the units were refrigerated at 4 to 6 degrees c ...19902349628
the survival of streptococci and enterococci in animal feed and on straw with particular reference to streptococcus uberis.the survival of streptococcus uberis, strep. bovis, enterococcus faecalis spp. faecalis and ent. faecium in animal feed and on wheat straw was studied for one month. streptococcus bovis survived the best in feed and strep. uberis the worst while on straw ent. faecium was the most resilient species and there was little to choose between the other three. the recovery of all species, excepting strep. bovis, on selective and non-selective agar was comparable. the growth of strep. bovis, on the other ...19902351619
cloning and heterospecific expression of the resistance determinant vana encoding high-level resistance to glycopeptides in enterococcus faecium bm4147.fragments of plasmid pip816, which confers high-level glycopeptide resistance in enterococcus faecium bm4147, were cloned into a conjugative gram-negative-gram-positive shuttle vector. the resulting hybrids were transferred by conjugation from escherichia coli to enterococcus faecalis and bacillus thuringiensis. a 4-kilobase ecori fragment from pip816 was found to confer vancomycin resistance in these hosts but not in e. coli or bacillus subtilis.19902360831
minimum inhibitory concentrations and disk diffusion zone diameter for selected antibiotics against streptococci isolated from bovine intramammary infections.the antimicrobial susceptibility to 11 antibiotics was determined of 358 streptococcal isolates representing six species was determined. all isolates were from milk samples obtained from clinical or subclinical cases of bovine mastitis. agar disk diffusion zone diameters and minimum inhibitory concentrations were obtained for all isolates. of the antibiotics tested that are available for mastitis therapy, cephalothin, penicillin, ampicillin, novobiocin, and erythromycin demonstrated acceptable a ...19902365883
[studies of aztreonam in neonates].absorption and excretion of aztreonam (azt) in neonates were studied and its clinical evaluation in 10 cases of neonates was performed using 1 hour intravenous drip infusion. 1. serum concentrations of azt in 7 neonates younger than 11 days of age were lower than those in infants. 2. serum concentrations of azt in 5 neonates given 20 mg/kg reached their peaks at the end of intravenous drip infusion with an average value of 45.8 +/- 10.41 micrograms/ml, and t 1/2 was 2.77 +/- 0.32 hours on the av ...19902374296
[antibiotic prophylaxis with cefotiam in transurethral resection of the prostate].over a period of 7 months, 50 patients underwent a trans-urethral resection of the prostate (turp), this intervention is classified as "clear-contamined". the antibiotic prophylactic protocol, the subject of this study, was the following: cefotiam 2 g iv with the induction of anesthesia, 1 g 3 hours later and 1 g iv with the removal of the urethral catheter. results: there were 3 early post-operative urinary tract infections, one of these patients was symptomatic, at the time of removal of the u ...19902385454
[immunological analysis of streptococcus sanguis antigens].the exact cause of behçet's disease is still unknown. recently, advanced bacterial studies revealed that behçet's disease was related to streptococcus (s.) sanguis. however, the antigenicity of s. sanguis has not been fully studied. in this study, we clarified the antigenicity of s. sanguis. we made s. sanguis antigens: mechanical braun extract (mbe) and crude cell wall (ccw) from the whole cells, membrane fraction (mf) and cytoplasmic fraction (cf) from mbe, cell wall fragment (cwf) and lipotei ...19902396588
[effects of heat treated cells of intestinal lactic acid bacteria in rats fed a deoxycholic acid diet].effects of the administration of heat treated cells of intestinal lactic acid bacteria were examined in rats fed a deoxycholic acid (dca) diet. male wistar rats were given a 0.25% dca diet with or without the heat treated cells of enterococcus faecalis ad 1001 (efh-1) or lactobacillus reuteri ad 0002 (lrh-2) for 4 weeks. abnormal increases in serum got, gpt, un and lipoproteins were observed in the rats fed the dca diet. furthermore, severe lesions in the kidney as well as in the liver were foun ...19902401316
the life and times of the enterococcus.enterococci are important human pathogens that are increasingly resistant to antimicrobial agents. these organisms were previously considered part of the genus streptococcus but have recently been reclassified into their own genus, called enterococcus. to date, 12 species pathogenic for humans have been described, including the most common human isolates, enterococcus faecalis and e. faecium. enterococci cause between 5 and 15% of cases of endocarditis, which is best treated by the combination o ...19902404568
the determination of the anomeric configuration of glycosyl-phosphoryl linkages of immunogenic phosphoglycans.phosphoglycans from the cell wall of many strains of streptococci contain terminal carbohydrate units linked by phosphodiester bridges to other residues of the glycans. in the immune response to phosphoglycans, the terminal carbohydrate-phosphate moieties function as antigenic determinants and induce the synthesis of antibodies with specificity for the glycosyl-phosphoryl units. it has now been found that such terminal carbohydrate units can be removed by treatment of the glycans with appropriat ...19852409837
antigenic variation of indigenous streptococci.isolates of group d streptococci indigenous to the murine oral cavity were studied to detect the occurrence of antigenic variation. group d streptococci cultured from molar homogenates of balb/c mice were randomly selected for study on the basis of distinctive colony morphology. isolates obtained over a 12-week period were biotyped using the api 20s system, and subjected to lancefield extraction and rocket immunoelectrophoresis for serotyping. all isolates were compared with an arbitrarily selec ...19852410468
the phylogenetic position of streptococcus and enterococcus.streptococcus pyogenes, s. equinus, s. bovis, s. salivarius, s. sanguis, s. mutans, s. rattus, s. cricetus, s. lactis, s. raffinolactis and enterococcus faecalis have been characterized by oligonucleotide cataloguing of their 16s ribosomal rna. all the organisms form a loose but coherent group that is phylogenetically equivalent to those of lactobacilli, bacilli, the brochothrix and listeria group, and related taxa that constitute one of several sublines within the 'clostridium' branch of gram-p ...19852410543
[reactivity to bacterial peptidoglycans in a phagocytosis system. the range of immunological specificity of escherichia coli peptidoglycan].the antigenic specificity of e. coli m17 peptidoglycans (pg) was studied in the test system based on the stimulation of neutrophils with pg opsonized with the whole and exhausted igg fraction of human serum. within the generic taxon, the pg under study were similar in their antigenic properties. the opsonic activity of igg exhausted with the preparations of different e. coli strains decreased by 93.2-95.8%. an essential difference of e. coli pg from similar components of other representatives of ...19852413663
streptococcal cytoplasmic ph is regulated by changes in amount and activity of a proton-translocating atpase.the streptococcus faecalis h+-atpase (f1 x f0 complex) level was elevated when the cytoplasmic ph was shifted below 7.5. the elevated level was attained by the increase in functional unit (f1 x f0 complex) in membranes, but not by the activation of the enzyme. our data strongly suggested that the increase in enzyme arises from stimulation of enzyme biosynthesis. when calls growing at ph 7.6 were transferred to an acid medium with a ph below 7, the amount of h+-atpase increased. the amount of h+- ...19862416756
ion extrusion systems in bacteria. 19852418727
primary and secondary transport of cations in bacteria. 19852418733
comparative adhesion of seven species of streptococci isolated from the blood of patients with sub-acute bacterial endocarditis to fibrin-platelet clots in vitro.the adhesion to fibrin-platelet clots in vitro of 21 strains of streptococci isolated from the blood of patients with sub-acute bacterial endocarditis (sabe) was measured. the species, in order of greatest adhesion, were streptococcus faecalis, streptococcus mutans, streptococcus milleri, streptococcus sanguis, dextran-positive streptococcus mitior, dextran-negative streptococcus mitior and streptococcus salivarius. individual strains within species, however, cannot be assumed to be representati ...19862422150
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