Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| prevalence and risk factors of early fecal carriage of enterococcus faecalis and staphylococcus spp and their antimicrobial resistant patterns among healthy neonates born in a hospital setting in central saudi arabia. | to investigate the prevalence, antibiotic resistant profiles, and risk factors of early fecal carriage of enterococcus faecalis (e. faecalis) and staphylococci among 150 healthy saudi neonates born in a hospital setting in central saudi arabia. | 2016 | 26905350 |
| evolution of resistance to cationic biocides in streptococcus mutans and enterococcus faecalis. | the aim of this study was to investigate whether streptococcus mutans and enterococcus faecalis develop resistance to the cationic biocides chlorhexidine (chx), cetylpyridinium chloride (cpc), and 12-methacryloyloxydodecylpyridinium bromide (mdpb). | 2016 | 26904979 |
| genetic environment of the transferable oxazolidinone/phenicol resistance gene optra in enterococcus faecalis isolates of human and animal origin. | aim of this study was to analyse 17 non-related enterococcus faecalis isolates of human and animal origin for the genetic environment of the novel oxazolidinone/phenicol resistance gene optra. | 2016 | 26903276 |
| evaluation of polymorphisms in pbp4 gene and genetic diversity in penicillin-resistant, ampicillin-susceptible enterococcus faecalis from hospitals in different states in brazil. | the aim of the present study was to verify whether penicillin-resistant, ampicillin-susceptible enterococcus faecalis (prasef) occurred in brazil prior to the beginning of the 21st century, and to verify whether ampicillin susceptibility can predict susceptibility to other β-lactams in e. faecalis with this inconsistent phenotype. the presence of polymorphisms in the pbp4 gene and genetic diversity among the isolates were investigated. of 21 prasef analyzed, 5 (23.8%) and 4 (19.0%) were imipenem ... | 2016 | 26903013 |
| clinical characteristics and antimicrobial patterns in complicated intra-abdominal infections: a 6-year epidemiological study in southern china. | complicated intra-abdominal infection (ciais) are a common and important cause of morbidity worldwide. in this study, the clinical features, microbiological profiles, antimicrobial patterns and treatments of 3233 ciai patients (mean age, 47.6 years; 54.7% male) with 3531 hospitalisations from 2008-2013 were retrospectively investigated. the most commonly isolated bacteria were escherichia coli (47.6%), klebsiella pneumoniae (16.9%), enterococcus faecalis (10.4%) and pseudomonas aeruginosa (8.8%) ... | 2016 | 26899413 |
| comparison of telavancin and vancomycin lock solutions in eradication of biofilm-producing staphylococci and enterococci from central venous catheters. | results of a study of the activity of antibiotic lock solutions of vancomycin and telavancin against biofilm-forming strains of staphylococcus epidermidis, enterococcus faecalis, and staphylococcus aureus are reported. | 2016 | 26896504 |
| killing of vre enterococcus faecalis by commensal strains: evidence for evolution and accumulation of mobile elements in the absence of competition. | enterococci are members of the gastrointestinal tract of humans and most animals that, over the past 3 decades, have emerged as leading causes of multidrug resistant hospital acquired infection (hai). in addition to their general hardiness, many traits have entered enterococcal lineages through horizontal gene transfer, which has led to the evolution of pathogenic hospital-associated lineages uniquely adapted for survival and proliferation in the antibiotic perturbed ecology of the gastrointesti ... | 2016 | 26939857 |
| deletion of fabn in enterococcus faecalis results in unsaturated fatty acid auxotrophy and decreased release of inflammatory cytokines. | the gram-positive bacterium enterococcus faecalis can cause life-threatening infections and is resistant to several commonly used antibiotics. the type ii fatty acid pathway in bacteria is discussed as a potential target for antimicrobial therapy. however, it was shown that inhibition or deletion of its enzymes can be rescued in gram-positive bacteria by supplementation with fatty acids. here we show that by deletion of the fabn gene, which is essential for unsaturated fatty acid (ufa) synthesis ... | 2016 | 27009913 |
| thymidylate limitation potentiates cephalosporin activity toward enterococci via an exopolysaccharide-based mechanism. | multidrug resistant enterococci are major causes of nosocomial infections. prior therapy with cephalosporins increases the risk of developing an enterococcal infection due to the intrinsic resistance of enterococci to these antibiotics. while progress has been made toward understanding the genetic and biochemical mechanisms of cephalosporin resistance, available data indicate that as-yet-unidentified resistance factors must exist. here, we describe results of a screen to identify small molecules ... | 2016 | 27008338 |
| molecular diagnosis of urinary tract infections by semi-quantitative detection of uropathogens in a routine clinical hospital setting. | the objective of our study was the development of a semi-quantitative real-time pcr to detect uropathogens. two multiplex pcr reactions were designed to detect escherichia coli, klebsiella spp., enterobacter spp., citrobacter spp., proteus mirabilis, enterococcus faecalis, and pseudomonas aeruginosa. 16s based pcr was performed in parallel to detect gram-positive and gram-negative bacteria. firstly to identify non-targeted agents of infection in the same urine specimen, and secondly to quantify ... | 2016 | 26954694 |
| co-location of the oxazolidinone resistance genes optra and cfr on a multiresistance plasmid from staphylococcus sciuri. | to identify and characterize the oxazolidinone/phenicol resistance gene optra in staphylococcus isolates. | 2016 | 26953332 |
| resistance to antimicrobial agents among enterococci isolated from fecal samples of wild marine species in the southern coast of brazil. | the purpose of this study was to evaluate species distribution, antimicrobial resistance profiles, and presence of resistance genes in enterococci isolated from fecal samples of wild marine species, including seabirds (n=12), sea turtles (n=8), and mammals (n=3) found alive or dead in southern coast of brazil. enterococci were classified based on phenotypic and genotypic characteristics, tested for antibiotic susceptibility, and the presence of tet(s), tet(m), tet(l), mrsc, and erm(b) genes by p ... | 2016 | 26952995 |
| cysteamine enhances biofilm eradication efficacy of calcium hydroxide. | calcium hydroxide (ca[oh]2) is a widely used interappointment dressing, but its antibacterial property is compromised by dentin. hence, the addition of chlorhexidine (chx) with ca(oh)2 has been proposed. however, the antimicrobial efficacy of this mixture compared with ca(oh)2 alone is currently still debatable. cysteamine is a mucolytic agent used to reduce the viscosity of mucus through the disruption of proteins, which are also important components of the extracellular matrix of biofilms. the ... | 2016 | 26951960 |
| effects of dentin debris on the antimicrobial properties of sodium hypochlorite and etidronic acid. | the purpose of this study was to determine the influence of dentin powder on the concentration, ph, and antimicrobial activity of sodium hypochlorite (naocl) alone and combined with etidronic acid (hebp). | 2016 | 26951957 |
| comparative analysis of protaper and waveone systems to reduce enterococcus faecalis from root canal system in primary molars--an in vitro study. | to assess, in vitro, the ability of the protaper(™) and waveone(™) systems to reduce enterococcus faecalis contamination in primary molars. | 2016 | 26950813 |
| in silico dissection of type vii secretion system components across bacteria: new directions towards functional characterization. | type vii secretion system (t7ss) is one of the factors involved in virulence of mycobacterium tuberculosis h37rv. numerous research efforts have been made in the last decade towards characterizing the components of this secretion system. an extensive genome-wide analysis through compilation of isolated information is required to obtain a global view of diverse characteristics and pathogenicity-related aspects of this machinery. the present study suggests that differences in structural components ... | 2016 | 26949095 |
| invasive enterococcal infections in poland: the current epidemiological situation. | the aim of this study was to investigate human invasive isolates of enterococci, obtained through prospective surveillance in poland. the consecutive enterococcal isolates were collected in 30 hospitals between may 2010 and june 2011, and studied by species identification, antimicrobial susceptibility testing and, for enterococcus faecium by detection of markers specific for the hospital meroclone, multilocus vntr analysis (mlva) and multilocus sequence typing (mlst). additionally, the genomic d ... | 2016 | 26946510 |
| antibacterial and cytotoxic triterpenoids from the roots of combretum racemosum. | a new pentacyclic triterpenoid glucoside, together with fourteen known compounds, was isolated from the roots of combretum racemosum. combretaceae). the structure of the new compound was established as 28-o-β-d-glucopyranosyl-2α,3β,21β,23-tetrahydroxyolean-18-en-28-oate (1) on the basis of detailed spectroscopic data including ms, 1d, and 2d nmr. the inhibitory activity of compounds 1-15 against promyelocytic leukemia hl-60 and human erythromyeloblastoid leukemia k562 cell lines was evaluated. c ... | 2016 | 26946378 |
| time is of the essence: the impact of delayed antibiotic therapy on patient outcomes in hospital-onset enterococcal bloodstream infections. | with increasing prevalence of vancomycin-resistant enterococci (vre), appropriate antibiotic therapy for enterococcal bloodstream infections (ebsi) can be delayed. data regarding the impact of delayed therapy on ebsi outcomes are conflicting, and the time delay most strongly associated with poor outcomes has not been defined. | 2016 | 26945013 |
| occurrence of vancomycin-resistant and -susceptible enterococcus spp. in reclaimed water used for spray irrigation. | reclaiming municipal wastewater for agricultural, environmental, and industrial purposes is increasing in the united states to combat dwindling freshwater supplies. however, there is a lack of data regarding the microbial quality of reclaimed water. in particular, no previous studies have evaluated the occurrence of vancomycin-resistant enterococci (vre) in reclaimed water used at spray irrigation sites in the united states. to address this knowledge gap, we investigated the occurrence, concentr ... | 2016 | 26942838 |
| surveillance for linezolid resistance via the zyvox® annual appraisal of potency and spectrum (zaaps) programme (2014): evolving resistance mechanisms with stable susceptibility rates. | the objective of this study was to report the linezolid in vitro activity observed during the zyvox(®) annual appraisal of potency and spectrum (zaaps) programme for 2014. | 2016 | 27013481 |
| susceptibility of contemporary isolates to fosfomycin: a systematic review of the literature. | the aim of this review was to evaluate the susceptibility of contemporary gram-positive and gram-negative bacteria to fosfomycin. pubmed and scopus databases were systematically searched to identify studies published in print or electronically from january 2010 until june 2015. in total, 84 studies were selected. susceptibility to fosfomycin of staphylococcus aureus ranged between 33.2% and 100% (frequency=91.7%, 95% confidence interval 88.7-94.9%), of enterococcus spp. from 30% to 100% (enteroc ... | 2016 | 27013000 |
| fungal naphtho-γ-pyrones: potent antibiotics for drug-resistant microbial pathogens. | four naphtho-γ-pyrones (fonsecinones a and c and aurasperones a and e) were identified as potential antibacterial agents against escherichia coli, extended-spectrum β-lactamase (esbl)-producing e. coli, pseudomonas aeruginosa, enterococcus faecalis, and methicillin-resistant staphylococcus aureus (mrsa) in an in vitro antibacterial screen of 218 fungal metabolites. fonsecinone a (2) exhibited the most potent antibacterial activity, with minimum inhibitory concentrations (mics) of 4.26, 17.04, an ... | 2016 | 27063778 |
| [the effect of a combined nanoparticulate/calcium hydroxide medication on the biofilm of enterococcus faecalis in starvation phase]. | to evaluate the efficacy of ca(oh)2 with a silver nanoparticle suspension to eliminate the biofilm of enterococcus faecalis (e. faecalis) in starvation phase. | 2016 | 27063301 |
| [persistence of a st6 clone of enterococcus faecalis genotype vanb2 in two hospitals in aragon (spain)]. | in order to study the evolution of the outbreak that occurred between 2009 and 2010 in 3 hospitals in zaragoza, all vancomycin-resistant clinical enterococcus faecalis isolates identified between 2011 and 2013 at these hospitals were characterised. | 2016 | 27059750 |
| oritavancin activity tested against molecularly characterized staphylococci and enterococci displaying elevated linezolid mic results. | oritavancin (mic50/90, 0.03/0.06 to 0.12 μg/ml) had potent activity against linezolid-resistant staphylococci, as well as enterococcus faecalis and enterococcus faecium (oritavancin mic50/90, 0.015/0.12 μg/ml against both species). all linezolid-resistant isolates were inhibited by oritavancin at ≤0.12 μg/ml. these results confirmed the absence of cross-resistance between linezolid and oritavancin in staphylococci and enterococci. | 2016 | 27001823 |
| quantification of lipoteichoic acid contents and cultivable bacteria at the different phases of the endodontic retreatment. | the infectious content of root canals, including bacteria and lipoteichoic acid (lta), cause injuries to the periapical tissues. the purpose of this clinical study was to quantify the levels of both lta and cultivable bacteria at the different phases of endodontic retreatment (er) of teeth with post-treatment apical periodontitis. it also aimed to investigate the presence of gram-positive microorganisms before and after chemomechanical preparation (cmp) and intracanal medication (icm). | 2016 | 27000273 |
| antimicrobial action of calcium hydroxide-based endodontic sealers after setting, against e. faecalis biofilm. | enterococcus faecalis are gram positive bacteria that can mostly resist endodontic therapy, inducing persistent infection in the root canal system. endodontic sealers with antimicrobial activity may help eliminate residual microorganisms that survive endodontic treatment. the present study aimed at comparing the antimicrobial activity of acroseal, sealapex and ah plus endodontic sealers in an in vitro biofilm model. bovine dentin specimens (144) were prepared, and twelve blocks for each sealer a ... | 2016 | 26981759 |
| rapid evolution of microbe-mediated protection against pathogens in a worm host. | microbes can defend their host against virulent infections, but direct evidence for the adaptive origin of microbe-mediated protection is lacking. using experimental evolution of a novel, tripartite interaction, we demonstrate that mildly pathogenic bacteria (enterococcus faecalis) living in worms (caenorhabditis elegans) rapidly evolved to defend their animal hosts against infection by a more virulent pathogen (staphylococcus aureus), crossing the parasitism-mutualism continuum. host protection ... | 2016 | 26978164 |
| chemical composition, cytotoxic and antibacterial activities of the essential oil from the tunisian ononis angustissima l. (fabaceae). | the chemical composition, cytotoxic and antibacterial activities of the hydrodistilled essential oil of the aerial parts of ononis angustissima from south tunisia has been evaluated. the oil yield was 0.04% (w/w). the chemical composition, determined by gc and gc-ms is reported for the first time. forty-five components, accounting for 93.7% of the total oil have been identified. the oil was characterized by a high proportion of oxygenated sesquiterpenes (33.2%), followed by sesquiterpene hydroca ... | 2016 | 26972463 |
| l-lactic acid production by combined utilization of agricultural bioresources as renewable and economical substrates through batch and repeated-batch fermentation of enterococcus faecalis rky1. | enterococcus faecalis rky1 was used to produce l-lactic acid from hydrol, soybean curd residues (scr), and malt. hydrol was efficiently metabolized to l-lactic acid with optical purity of >97.5%, though hydrol contained mixed sugars such as glucose, maltose, maltotriose, and maltodextrin. combined utilization of hydrol, scr, and malt was enough to sustain lactic acid fermentation by e. faecalis rky1. in order to reduce the amount of nitrogen sources and product inhibition, cell-recycle repeated- ... | 2016 | 26970921 |
| enterococcus faecalis ebp pili are important for cell-cell aggregation and intraspecies gene transfer. | enterococcus faecalis is an opportunistic pathogen that ranks among the leading causes of biofilm-associated infections. we previously demonstrated that the endocarditis- and biofilm-associated pili (ebp) of e. faecalis play a major role in biofilm formation, adherence to abiotic surfaces and experimental infections. in this study, derivatives of e. faecalis strain og1 were engineered to further characterize functions of ebp pili. loss of pili resulted in a 36-fold decrease in the number of clos ... | 2016 | 26967674 |
| point-of-use water disinfection using ultraviolet and visible light-emitting diodes. | improvements in point-of-use (pou) drinking water disinfection technologies for remote and regional communities are urgently needed. conceptually, uv-c light-emitting diodes (leds) overcome many drawbacks of low-pressure mercury tube based uv devices, and uv-a or visible light leds also show potential. to realistically evaluate the promise of led disinfection, our study assessed the performance of a model 1.3 l reactor, similar in size to solar disinfection bottles. in all, 12 different commerci ... | 2016 | 26967007 |
| heat-killed enterococcus faecalis ef-2001 ameliorates atopic dermatitis in a murine model. | recent reports have shown the immunomodulatory effect of heat-killed lactic acid bacteria. atopic dermatitis (ad) is an allergic skin disease, caused by immune dysregulation among other factors. the aim of this study was to assess the effect of heat-killed enterococcus faecalis ef-2001 (ef-2001) on ad. we established an in vivo ad model by repeated local exposure of dermatophagoides farinae extract (dfe; house dust mite extract) and 2,4-dinitrochlorobenzene (dncb) to the ears of mice. after oral ... | 2016 | 26959058 |
| first japanese case of infectious endocarditis due to enterococcus faecalis small-colony variants. | a male patient was admitted to our hospital due to infectious endocarditis. he had been treated with levofloxacin for 6 weeks, sulbactam/cefoperazone for 4 weeks, and benzylpenicillin for 2 days prior to valve replacement surgery. gram-positive cocci, with morphology consistent with γ-streptococcus, were detected in blood cultures obtained at admission, as well as in vegetation obtained from the aortic valve. however, the strain could not be identified using biochemical methods. sequencing of th ... | 2016 | 27094238 |
| antimicrobial activity of tetraacetylethylenediamine-sodium perborate versus sodium hypochlorite against enterococcus faecalis. | background. this study evaluated the antimicrobial activity of tetraacetylethylenediamine-sodium perborate (taed-sp) in comparison to 2.5% and 5% sodium hypochlorite (naocl) against enterococcus faecalis. methods. a standard suspension of e. faecalis was inoculated on 60 plates containing mueller-hinton agar culture medium. four sterile disks of beckman filtration paper were placed on each plate. taed-sp, 5% and 2.5% naocl were placed on three disks. sterile physiologic saline was placed on the ... | 2016 | 27092214 |
| q69 (an e. faecalis-infecting bacteriophage) as a biocontrol agent for reducing tyramine in dairy products. | biogenic amines (bas) are low molecular weight nitrogenous compounds with biological activity, formed from amino acids by decarboxylation. bas are naturally present in all living organisms playing essential roles. however, their accumulation in food through the metabolic activity of certain microorganisms constitutes a toxicological hazard. among foods, cheeses accumulate some of the highest concentrations of bas since they provide an ideal environment for their accumulation. most of the methods ... | 2016 | 27092117 |
| nondermal irritating hyperosmotic nanoemulsions reduce treatment times in a contamination model of wound healing. | increased microbial burden within the wound often complicates wound healing and may lead to subsequent infection or delayed healing. here, we investigate a novel topical for addressing wound contamination that utilizes hyperosmotic saccharides with a cell membrane disrupting emulsion. these hyperosmotic nanoemulsions (hne) were administered topically in a full-thickness biopsy model of wound healing. results show that hne were well tolerated in noninfected animals with no indications of dermal i ... | 2016 | 27090977 |
| complete genome sequence of enterococcus faecalis ld33, a bacteriocin-producing strain. | enterococcus faecalis ld33 strain was originally isolated from traditional naturally fermented cream in inner mongolia of china. its complete genome sequence was carried out using the illumina hiseq and the pacbio rsii platform. the genome only has a circular chromosome and a gc content of 37.58%. other core information shown in the genome sequencing results further insight on this bacterium's genetic elements for bacteriocin production and the genes related to respiratory chain. | 2016 | 27090021 |
| effect of the quorum-sensing luxs gene on biofilm formation by enterococcus faecalis. | enterococcus faecalis is the species of bacterium most frequently isolated from the root canals of teeth that exhibit chronic apical periodontitis refractory to endodontic treatment. in this study, we evaluated the effect of the s-ribosylhomocysteine lyase (luxs) quorum-sensing gene on e. faecalis biofilm formation by constructing a knockout mutant. the biofilms formed by both e. faecalis and its luxs mutant strain were evaluated using the mtt method. important parameters that influence biofilm ... | 2016 | 27080421 |
| comparison of clinical outcomes and risk factors in polymicrobial versus monomicrobial enterococcal bloodstream infections. | enterococcal bloodstream infections (ebsis) are frequently polymicrobial but scant data describe the outcomes and risk factors of polymicrobial ebsi. this study describes the outcomes and risk factors of polymicrobial versus monomicrobial ebsi. | 2016 | 27079241 |
| influence of working length and foraminal enlargement on foramen morphology and sealing ability. | the present study evaluated the influence of the working length and foraminal enlargement on the sealing ability and anatomy of the apical region of the root. | 2016 | 27054864 |
| detection of vancomycin resistance among enterococcus faecalis and staphylococcus aureus. | vancomycin remains the drug of choice for resistant gram positive infections caused by enterococcus spp and methicillin resistant staphylococcus aureus (mrsa). increased use of vancomycin has led to frank resistance and increase in mic (mic creep). vancomycin intermediate staphylococcus aureus (visa), vancomycin resistant staphylococcus aureus (vrsa) & vancomycin resistant enterococci (vre) are important emerging nosocomial pathogens resulting in treatment failures. | 2016 | 27042459 |
| maternal antibiotic treatment impacts development of the neonatal intestinal microbiome and antiviral immunity. | microbial colonization of the infant gastrointestinal tract (git) begins at birth, is shaped by the maternal microbiota, and is profoundly altered by antibiotic treatment. antibiotic treatment of mothers during pregnancy influences colonization of the git microbiota of their infants. the role of the git microbiota in regulating adaptive immune function against systemic viral infections during infancy remains undefined. we used a mouse model of perinatal antibiotic exposure to examine the effect ... | 2016 | 27036912 |
| indomethacin injury to the rat small intestine is dependent upon biliary secretion and is associated with overgrowth of enterococci. | nsaiduse is limited due to the drugs' toxicity to the gastrointestinal mucosa, an action incompletely understood. lower gut injury induced bynsaids is dependent on bile secretion and is reported to increase the growth of a number of bacterial species, including an enterococcal species,enterococcus faecalis this study examined the relationships between indomethacin (indo)-induced intestinal injury/bleeding, small bowel overgrowth (sbo) and dissemination of enterococci, and the contribution of bil ... | 2016 | 27033447 |
| synthesis variants of quaternary ammonium polyethyleneimine nanoparticles and their antibacterial efficacy in dental materials. | resin-based dental materials allow bacterial growth on their surface and lack antibacterial activity, leading to functional and esthetic failure. quaternary ammonium polyethyleneimine (qpei) nanoparticles (nps) incorporated in resin-based composite at 2% wt/wt have demonstrated prolonged and complete inhibition of bacterial growth. this study focused on optimization of qpei np synthesis to reduce the concentration required for bacterial growth inhibition. the objective here was to enhance antimi ... | 2016 | 27032864 |
| posaida: presence of staphylococcus aureus/mrsa and enterococcus/vre in danish ambulances. a cross-sectional study. | every year approximately one out of ten danish patients contracts a healthcare associated infection (hai). staphylococcus aureus and enterococcus are prominent in the group of pathogenic bacteria that underlie hais, causing unnecessary inconvenience and prolonging hospitalization. bacterial colonization often occurs due to indirect patient-to-patient transmission, caused by poor hygiene compliance. this study aims to determine the level of contamination with s. aureus/mrsa and enterococcus/vre o ... | 2016 | 27029410 |
| comparison of hospital room surface disinfection using a novel ultraviolet germicidal irradiation (uvgi) generator. | the estimated 721,800 hospital acquired infections per year in the united states have necessitated development of novel environmental decontamination technologies such as ultraviolet germicidal irradiation (uvgi). this study evaluated the efficacy of a novel, portable uvgi generator (the torch, chlordisys solutions, inc., lebanon, nj) to disinfect surface coupons composed of plastic from a bedrail, stainless steel, chrome-plated light switch cover, and a porcelain tile that were inoculated with ... | 2016 | 27028152 |
| spatial organization of cell wall-anchored proteins at the surface of gram-positive bacteria. | bacterial surface proteins constitute an amazing repertoire of molecules with important functions such as adherence, invasion, signalling and interaction with the host immune system or environment. in gram-positive bacteria, many surface proteins of the "lpxtg" family are anchored to the peptidoglycan (pg) by an enzyme named sortase. while this anchoring mechanism has been clearly deciphered, less is known about the spatial organization of cell wall-anchored proteins in the bacterial envelope. h ... | 2016 | 27025379 |
| probiotic properties of lactic acid bacteria isolated from human milk. | the objective of this study was to identify and characterize lactic acid bacteria isolated from human milk, with an emphasis on their probiotic properties. | 2016 | 27159339 |
| reactive arthritis caused by urinary tract infection. | we report the case of a 58-year-old man presenting with chest pain who underwent percutaneous coronary intervention (pci). the patient subsequently developed a fever over 38°c, pain on micturition, and cloudy urine 3 days following pci. urine cultures were positive for escherichia coli and enterococcus faecalis, whereas blood cultures were negative. arthritis occurred two weeks following urinary tract infection (uti). we herein present a rare case of reactive arthritis caused by uti following pc ... | 2016 | 27150879 |
| evaluation of antimicrobial efficacy of cetrimide and glycyrrhiza glabra l. extract against enterococcus faecalis biofilm grown on dentin discs in comparison with naocl. | this study aimed to determine the antimicrobial efficacy of naocl, cetrimide, and glycyrrhiza glabra l. extract against enterococcus faecalis biofilms on dentine discs. broth microdilution method was used to determine minimal bactericidal concentrations (mbcs) of the agents. a biofilm susceptibility assay was performed using e. faecalis biofilms grown on dentine discs. minimal bactericidal concentrations (mbcs) of naocl (0.5%), cetrimide (0.015%), and g. glabra l. extract (0.25%) were applied fo ... | 2016 | 27150551 |
| protein translation machinery holds a key for transition of planktonic cells to biofilm state in enterococcus faecalis: a proteomic approach. | enterococcus faecalis is a member of human gut microflora causing nosocomial infection involving biofilm formation. ethyl methyl sulfonate induced mutants were analysed using crystal violet assay, sem and clsm microscopy which confirmed ak-e12 as biofilm efficient and ak-f6 as biofilm deficient mutants. growth curve pattern revealed ak-e12 was fast growing whereas, ak-f6 was found slow growing mutant. 2d-electrophorosis and maldi-tof analysis revealed over and underexpression of many translation ... | 2016 | 27144316 |
| virulence genes among enterococcus faecalis and enterococcus faecium isolated from coastal beaches and human and nonhuman sources in southern california and puerto rico. | most enterococcus faecalis and e. faecium are harmless to humans; however, strains harboring virulence genes, including esp, gele, cyla, asa1, and hyl, have been associated with human infections. e. faecalis and e. faecium are present in beach waters worldwide, yet little is known about their virulence potential. here, multiplex pcr was used to compare the distribution of virulence genes among e. faecalis and e. faecium isolated from beaches in southern california and puerto rico to isolates fro ... | 2016 | 27144029 |
| simulated-use validation of a sponge atp method for determining the adequacy of manual cleaning of endoscope channels. | the objective of this study was to validate the relative light unit (rlu) cut-off of adequate cleaning of flexible colonoscopes for an atp (adenosine tri-phosphate) test kit that used a sponge channel collection method. | 2016 | 27142441 |
| effect of different mixing methods on the bacterial microleakage of calcium-enriched mixture cement. | calcium-enriched mixture cement is used in the field of endodontics. it is similar to mineral trioxide aggregate in its main ingredients.the present study investigated the effect of different mixing methods on the bacterial microleakage of cem cement. | 2016 | 27139578 |
| a silenced vana gene cluster on a transferable plasmid caused an outbreak of vancomycin-variable enterococci. | we report an outbreak of vancomycin-variable vana(+) enterococci (vve) able to escape phenotypic detection by current guidelines and demonstrate the molecular mechanisms for in vivo switching into vancomycin resistance and horizontal spread of the vana cluster. forty-eight vana(+) enterococcus faecium isolates and one enterococcus faecalis isolate were analyzed for clonality with pulsed-field gel electrophoresis (pfge), and their vana gene cluster compositions were assessed by pcr and whole-geno ... | 2016 | 27139479 |
| comparison of the antimicrobial efficacy of two antibiotics sparfloxacin and augmentin as experimental root canal irrigating solutions against enterococcus faecalis - an invitro study. | one of the main goals of endodontic treatment is root canal disinfection and to prevent subsequent chances of reinfection. adjuvant to instrumentation, root canal irrigants are required to eliminate the bacteria found on the root canal walls and lateral canals within the dentinal tubules. | 2016 | 27135003 |
| a novel in vitro co-culture model comprised of caco-2/rbl-2h3 cells to evaluate anti-allergic effects of food factors through the intestine. | the prevalence of type i allergic diseases such as food allergy and allergic rhinitis has increased. therefore, many studies have focused on food factors with anti-allergic activities in recent years. in order to investigate the effect of food factors on mast cell activation, a rbl-2h3 cell monoculture system has been widely used, in which various food factors have been reported to inhibit degranulation of rbl-2h3 cells. however, some orally administered food factors do not interact directly wit ... | 2016 | 27131754 |
| efficacy of 4 irrigation protocols in killing bacteria colonized in dentinal tubules examined by a novel confocal laser scanning microscope analysis. | the aim of this study was to determine the efficiency of 4 irrigation systems in eliminating bacteria in root canals, particularly in dentinal tubules. | 2016 | 27130334 |
| effect of dietary starch source and concentration on equine fecal microbiota. | starch from corn is less susceptible to equine small intestinal digestion than starch from oats, and starch that reaches the hindgut can be utilized by the microbiota. the objective of the current study was to examine the effects of starch source on equine fecal microbiota. thirty horses were assigned to treatments: control (hay only), hc (high corn), ho (high oats), lc (low corn), lo (low oats), and lw (low pelleted wheat middlings). horses received an all-forage diet (2 wk; d -14 to d -1) befo ... | 2016 | 27128793 |
| the efficacy of umbelliferone, arbutin, and n-acetylcysteine to prevent microbial colonization and biofilm development on urinary catheter surface: results from a preliminary study. | we evaluated, in a preliminary study, the efficacy of umbelliferone, arbutin, and n-acetylcysteine to inhibit biofilm formation on urinary catheter. we used 20 urinary catheters: 5 catheters were incubated with enterococcus faecalis (control group); 5 catheters were incubated with e. faecalis in presence of umbelliferone (150 mg), arbutin (60 mg), and n-acetylcysteine (150 mg) (group 1); 5 catheters were incubated with e. faecalis in presence of umbelliferone (150 mg), arbutin (60 mg), and n-ace ... | 2016 | 27127655 |
| light-activated polymethylmethacrylate nanofibers with antibacterial activity. | the creation of an antibacterial material with triggerable properties enables us to avoid the overuse or misuse of antibacterial substances and, thus, prevent the emergence of resistant bacterial strains. as a potential light-activated antibacterial material, polymethylmethacrylate (pmma) nanofibers doped with silver nanoparticles (agnps) and meso-tetraphenylporphyrin (tpp) were prepared by electrospinning. tpp was chosen as an effectively reactive oxygen species (ros) producer. antibacterial te ... | 2016 | 27127048 |
| solar inactivation of enterococci and escherichia coli in natural waters: effects of water absorbance and depth. | the decay of sewage-sourced escherichia coli and enterococci was measured at multiple depths in a freshwater marsh, a brackish water lagoon, and a marine site, all located in california. the marine site had very clear water, while the waters from the marsh and lagoon contained colored dissolved organic matter that not only blocked light but also produced reactive oxygen species. first order decay rate constants of both enterococci and e. coli were between 1 and 2 d(-1) under low light conditions ... | 2016 | 27119980 |
| sealing ability of mta, cpm, and mbpc as root-end filling materials: a bacterial leakage study. | objectives to evaluate the sealing ability of three root-end filling materials (white mta, cpm, and mbpc) using an enterococcus faecalis leakage model. material and methods seventy single-root extracted human teeth were instrumented and root-ends were resected to prepare 3 mm depth cavities. root-end preparations were filled with white mta, cpm, and mbpc cements. enterococcus faecalis was coronally introduced and the apical portion was immersed in bhi culture medium with phenol red indicator. th ... | 2016 | 27119763 |
| solubility and bacterial sealing ability of mta and root-end filling materials. | objective to evaluate solubility and sealing ability of mineral trioxide aggregate (mta) and root-end filling materials. material and methods the materials evaluated were: mta, calcium silicate cement with zirconium oxide (csc/zro2), and zinc oxide/eugenol (zoe). solubility test was performed according to ansi/ada. the difference between initial and final mass of the materials was analyzed after immersion in distilled water for 7 and 30 days. retrograde cavities in human teeth with single straig ... | 2016 | 27119759 |
| antimicrobial activity and substantivity of uncaria tomentosa in infected root canal dentin. | the aim of this study was to analyze the antimicrobial activity and substantivity of uncaria tomentosa willd dc (cat's claw, cc) in root dentin contaminated with enterococcus faecalis. forty-eight human premolars were contaminated with e. faecalis (atcc 29212) and randomly divided into four groups according to the irrigant used during chemomechanical preparation (cmp): cc group: 2% cc gel; chx group: 2% chlorhexidine digluconate gel (chx); naocl group: 5.25% sodium hypochlorite (naocl); and ss g ... | 2016 | 27119588 |
| potent antimicrobial and antibiofilm activities of bacteriogenically synthesized gold-silver nanoparticles against pathogenic bacteria and their physiochemical characterizations. | the objective of this study was to develop a bimetallic nanoparticle with enhanced antibacterial activity that would improve the therapeutic efficacy against bacterial biofilms. bimetallic gold-silver nanoparticles were bacteriogenically synthesized using γ-proteobacterium, shewanella oneidensis mr-1. the antibacterial activities of gold-silver nanoparticles were assessed on the planktonic and biofilm phases of individual and mixed multi-cultures of pathogenic gram negative (escherichia coli and ... | 2016 | 27117745 |
| boron-doped diamond oxidation of amoxicillin pharmaceutical formulation: statistical evaluation of operating parameters, reaction pathways and antibacterial activity. | the electrochemical oxidation of a commercial amoxicillin formulation over a boron-doped diamond (bdd) anode was investigated. the effect of initial cod concentration (1-2 g/l), current density (30-50 ma/cm(2)), treatment time (15-90 min), initial ph (3-9) and electrolyte concentration (2-4 g/l nacl) on cod removal was assessed through a factorial design methodology. for the range of conditions in question, the first three single effects, as well as the interaction between cod and time were the ... | 2016 | 27117507 |
| acute severe aortic regurgitation: imaging with pathological correlation. | acute aortic regurgitation (ar) is an important finding associated with a wide variety of disease processes. its timely diagnosis is of utmost importance. delay in diagnosis could prove fatal. | 2016 | 27114975 |
| in vitro inactivation of enterococcus faecalis with a led device. | non-coherent light-emitting diodes (leds) are effective in a large variety of clinical indications; however, the bactericidal activity of leds is unclear, although the effectiveness of such lights is well known. currently, no studies have examined the effects of nir-led on bacteria. the aims of this study were to verify the antibacterial activity of 880-nm led irradiation on a bacterial suspension of enterococcus faecalis and to compare it with the actions of sodium hypochlorite (naocl) and the ... | 2016 | 27107704 |
| anterior mitral valve aneurysm: a rare sequelae of aortic valve endocarditis. | summaryin intravenous drug abusers, infective endocarditis usually involves right-sided valves, with staphylococcus aureus being the most common etiologic agent. we present a patient who is an intravenous drug abuser with left-sided (aortic valve) endocarditis caused by enterococcus faecalis who subsequently developed an anterior mitral valve aneurysm, which is an exceedingly rare complication. a systematic literature search was conducted which identified only five reported cases in the literatu ... | 2016 | 27249815 |
| treatment of mdr urinary tract infections with oral fosfomycin: a retrospective analysis. | limited options for treating mdr organisms have led clinicians to turn to older antimicrobial agents that may display activity against such infections. one such agent is fosfomycin, an oral drug with activity against a variety of gram-positive and -negative bacteria, but only approved for use in the usa for urinary tract infection (uti) due to escherichia coli and enterococcus faecalis. the purpose of this study was to assess the efficacy of fosfomycin treatment of mdr uti and identify predictor ... | 2016 | 27246234 |
| impact of the provaur stewardship programme on linezolid resistance in a tertiary university hospital: a before-and-after interventional study. | there is little evidence of the impact of antimicrobial stewardship programmes on antimicrobial resistance. | 2016 | 27246230 |
| temporal variabilities in genetic patterns and antibiotic resistance profiles of enterococci isolated from human feces. | temporal variabilities in the genetic patterns and antibiotic resistance profiles of enterococci were monitored over a 7-month period. enterococcus faecalis isolates (103 strains) collected from feces showed only one genetic pattern and antibiotic resistance profile within 0 d and 30 d. in contrast, after 60 d and 90 d, the genetic patterns and antibiotic resistance profiles of all e. faecalis isolates (8 strains) clearly differed within 30 d. these results indicate that the genetic patterns and ... | 2016 | 27265342 |
| enterococcus faecalis promotes osteoclast differentiation within an osteoblast/osteoclast co-culture system. | to investigate the effects of heat-killed enterococcus faecalis atcc 29212 and p25rc clinical strain (derived from an obturated root canal with apical periodontitis) on osteoclast differentiation within an osteoblast/osteoclast co-culture system. | 2016 | 27262294 |
| virulence traits and antibiotic resistance among enterococci isolated from dogs with periodontal disease. | periodontal disease - pd - is one of the most widespread diseases in dogs, but the role of this odontogenic infection in the dissemination of pathogenic bacteria present in the oral mucosa to other animals or pet owners is understudied. trying to unveil the putative pathogenicity of enterococci present in the gums of dogs diagnosed with pd, thirty-two animals were investigated during routine visits to a private veterinary clinic. seventy-one enterococci were recovered and characterized regarding ... | 2016 | 27260807 |
| evidence for persistent and shared bacterial strains against a background of largely unique gut colonization in hospitalized premature infants. | the potentially critical stage of initial gut colonization in premature infants occurs in the hospital environment, where infants are exposed to a variety of hospital-associated bacteria. because few studies of microbial communities are strain-resolved, we know little about the extent to which specific strains persist in the hospital environment and disperse among infants. to study this, we compared 304 near-complete genomes reconstructed from fecal samples of 21 infants hospitalized in the same ... | 2016 | 27258951 |
| topical formulation comprising fatty acid extract from cod liver oil: development, evaluation and stability studies. | the purpose of this study was to develop a pharmaceutical formulation containing fatty acid extract rich in free omega-3 fatty acids such as eicosapentaenoic acid and docosahexaenoic acid for topical use. although the health benefits of cod liver oil and other fish oils taken orally as a dietary supplement have been acknowledged and exploited, it is clear that their use can be extended further to cover their antibacterial properties. in vitro evaluation showed that 20% (v/v) fatty acid extract e ... | 2016 | 27258290 |
| antimicrobial and physicochemical characterization of biodegradable, nitric oxide-releasing nanocellulose-chitosan packaging membranes. | biodegradable composite membranes with antimicrobial properties consisting of nanocellulose fibrils (cnfs), chitosan, and s-nitroso-n-acetyl-d-penicillamine (snap) were developed and tested for food packaging applications. as a nitric oxide donor, snap was encapsulated into completely dispersed chitosan in 100 ml of 0.1 n acetic acid and was thoroughly mixed with cnfs to produce a composite membrane. the fabricated membranes had a uniform dispersion of chitosan and snap within the cnfs, which wa ... | 2016 | 27258235 |
| global emergence and dissemination of enterococci as nosocomial pathogens: attack of the clones? | enterococci are gram-positive bacteria that are found in plants, soil and as commensals of the gastrointestinal tract of humans, mammals, and insects. despite their commensal nature, they have also become globally important nosocomial pathogens. within the genus enterococcus, enterococcus faecium, and enterococcus faecalis are clinically most relevant. in this review, we will discuss how e. faecium and e. faecalis have evolved to become a globally disseminated nosocomial pathogen. e. faecium has ... | 2016 | 27303380 |
| postoperative infectious complications in patients undergoing holmium laser enucleation of the prostate: risk factors and microbiological analysis. | to examine the incidence of postoperative bacteriuria and febrile complications, and to investigate bacterial strains in the urine of patients undergoing holmium laser enucleation of the prostate. | 2016 | 27302684 |
| molecular analysis of vancomycin-resistant enterococci isolated from regional hospitals in trinidad and tobago. | geographic spread of vancomycin-resistant enterococci (vre) clones in cities, countries, or even continents has been identified by molecular techniques. this study aimed at characterizing virulent genes and determining genetic relatedness of 45 vre isolates from trinidad and tobago using molecular tools, including polymerase chain reaction, pulsed-field gel electrophoresis (pfge), and random amplification polymorphic dna (rapd). the majority (84%) of the isolates were enterococcus faecium posses ... | 2016 | 27299153 |
| the antimicrobial efficacy and dna binding activity of the copper(ii) complexes of 3,4,7,8-tetramethyl-1,10-phenanthroline, 4,7-diphenyl-1,10-phenanthroline and 1,2-diaminocyclohexane. | four copper(ii) complexes of the general structure [cu(l1)(l2)](2+), where l1 is (1s,2s)-diaminocyclohexane or (1r,2r)-diaminocyclohexane and l2 is 3,4,7,8-tetramethyl-1,10-phenanthroline (tmp) or 4,7-diphenyl-1,10-phenanthroline (dip), have been investigated in this study for their antimicrobial activity, short-term antimicrobial efficacy, and in vitro dna-binding affinity. against an expanded panel of bacterial and fungal strains in 12 species, minimal inhibitory concentrations (mic) for these ... | 2016 | 27293146 |
| tigecycline antimicrobial activity tested against clinical bacteria from latin american medical centres: results from sentry antimicrobial surveillance program (2011-2014). | bacterial organisms (n = 13,494) were consecutively collected in 2011-2014 from 21 latin american medical centres (11 nations). antimicrobial susceptibility was determined by broth microdilution at a central laboratory. tigecycline was very active against gram-positive organisms, with mic50/90 values of 0.06/0.06 µg/ml for staphylococcus aureus (n = 2878), 0.06/0.12 µg/ml for coagulase-negative staphylococci (n = 880), 0.06/0.06 µg/ml for enterococci (n = 708) and ≤0.03/≤0.03-0.06 µg/ml for stre ... | 2016 | 27291285 |
| fishing for gutta-percha-adhered biofilms in purulent post-treatment apical periodontitis. | this study investigated the possibility of depicting individual taxa in clinically relevant biofilms using fluorescent in situ hybridization (fish). gutta-percha samples were collected from the apical aspect of root canals associated with a chronic apical abscess (test samples, n = 8). corresponding control samples were obtained from previously filled root canals with apparently normal periapical tissues (n = 3). the transport medium was investigated for detached biofilm fragments using fish sta ... | 2016 | 27284969 |
| physicochemical characterisation and antimicrobial phototoxicity of an anionic porphyrin in natural deep eutectic solvents. | natural deep eutectic solvents (nades) are a newly discovered group of eutectics which has shown promise as a solvent in antimicrobial photodynamic therapy (apdt). the purpose of this study was to investigate preparations of an anionic porphyrin, meso-tetra-(4-carboxyphenyl)-porphine (tcpp), solubilised in nades, with regard to their physicochemical and antibacterial properties. the nades cs (ph∼0), chx (ph∼4) and mfg (ph∼1) solubilised tcpp with absorption maximum ∼443nm and emission maximum ∼6 ... | 2016 | 27269504 |
| neofiscalin a and fiscalin c are potential novel indole alkaloid alternatives for the treatment of multidrug-resistant gram-positive bacterial infections. | ten indole alkaloids were obtained from the marine sponge-associated fungus neosartorya siamensis kufa 0017. we studied the antimicrobial properties of these and of three other compounds previously isolated from the soil fungus n. siamensis kufc 6349. only neofiscalin a showed antimicrobial activity against gram-positive bacteria, including methicillin-resistant staphylococcus aureus (mrsa) and vancomycin-resistant enterococcus faecalis (vre); with a minimum inhibitory concentration (mic) of 8 μ ... | 2016 | 27268269 |
| emergence of vana gene among vancomycin-resistant enterococci in a tertiary care hospital of north - east india. | vancomycin-resistant enterococci (vre) have become one of the most challenging nosocomial pathogens with the rapid spread of the multi-drug resistant strain with limited therapeutic options. it is a matter of concern due to its ability to transfer vancomycin resistant gene to other organisms. the present study was undertaken to determine the emergence of vancomycin-resistant enterococci and the vana gene among the isolates in a tertiary care hospital of north-east india. | 2016 | 27241650 |
| antibacterial and antimetastatic potential of diospyros lycioides extract on cervical cancer cells and associated pathogens. | cervical cancer is among the most prevalent forms of cancer in women worldwide. diospyros lycioides was extracted using hexane, ethyl acetate, acetone, and methanol and finger print profiles were determined. the leaf material was tested for the presence of flavonoids, tannins, saponins, terpenoids, and cardiac glycosides using standard chemical methods and the presence of flavonoids and phenolics using thin layer chromatography. the total phenolic content was determined using folin-ciocalteu pro ... | 2016 | 27239210 |
| gram-positive uropathogens, polymicrobial urinary tract infection, and the emerging microbiota of the urinary tract. | gram-positive bacteria are a common cause of urinary-tract infection (uti), particularly among individuals who are elderly, pregnant, or who have other risk factors for uti. here we review the epidemiology, virulence mechanisms, and host response to the most frequently isolated gram-positive uropathogens: staphylococcus saprophyticus, enterococcus faecalis, and streptococcus agalactiae. we also review several emerging, rare, misclassified, and otherwise underreported gram-positive pathogens of t ... | 2016 | 27227294 |
| postneurosurgical central nervous system infection due to enterococcus faecalis successfully treated with intraventricular vancomycin. | infections from enterococcus faecalis and enterococcus faecium are uncommon in the post-neurosurgical intervention setting., [1, 2, 3, 4] intraventricular antibiotics are recommended when standard intravenous therapy fails. [5] here we present a case of post-neurosurgical ventriculitis, meningitis, and cerebritis in an oncology patient caused by refractory enterococcus faecalis successfully treated with intraventricular vancomycin. | 2016 | 27226704 |
| antimicrobial susceptibility and characterization of virulence genes of enterococcus faecalis isolates from teeth with failure of the endodontic treatment. | the aim of this study was to investigate the prevalence of virulence factors and the antimicrobial resistance of enterococcus faecalis isolates of teeth with failure of the endodontic treatment. | 2016 | 27221594 |
| antibacterial efficacy of calcium hypochlorite with vibringe sonic irrigation system on enterococcus faecalis: an in vitro study. | aim. the purpose of this study was to compare the in vitro efficacy of calcium hypochlorite (ca[ocl]2) and sodium hypochlorite (naocl) associated with sonic (vibringe) irrigation system in root canals which were contaminated with enterococcus faecalis. material and methods. the root canals of 84 single-rooted premolars were enlarged up to a file 40, autoclaved, inoculated with enterococcus faecalis, and incubated for 21 days. the samples were divided into 7 groups according to the irrigation pro ... | 2016 | 27218106 |
| increasing prevalence of aminoglycoside-resistant enterococcus faecalis isolates due to the aac(6')-aph(2") gene: a therapeutic problem in kermanshah, iran. | enterococci are important pathogens in nosocomial infections. various types of antibiotics, such as aminoglycosides, are used for treatment of these infections. enterococci can acquire resistant traits, which can lead to therapeutic problems with aminoglycosides. | 2016 | 27217920 |
| vana-type mrsa (vrsa) emerged in surface waters. | due to the widespread occurrence of meca-encoded methicillin resistance in staphylococcus aureus (mrsa), treatment of staphylococcal infections is shifted to glycopeptide antibiotics like vancomycin and teicoplanin. the selective pressure of glycopeptides has eventually led to the emergence of staphylococci with increased resistance. of great concern is vana-encoded high level vancomycin and teicoplanin resistance in mrsa (vrsa). therefore, this study aimed at investigating the occurrence of vrs ... | 2016 | 27216737 |
| genome-based characterization of hospital-adapted enterococcus faecalis lineages. | vancomycin-resistant enterococcus faecalis (vrefs) is an important nosocomial pathogen1,2. we undertook whole genome sequencing of e. faecalis associated with bloodstream infection in the uk and ireland over more than a decade to determine the population structure and genetic associations with hospital adaptation. three lineages predominated in the population, two of which (l1 and l2) were nationally distributed, and one (l3) geographically restricted. genome comparison with a global collection ... | 2016 | 27213049 |
| bactericidal effect of strong acid electrolyzed water against flow enterococcus faecalis biofilms. | this study evaluated the bactericidal effect of strong acid electrolyzed water (saew) against flow enterococcus faecalis biofilm and its potential application as a root canal irrigant. | 2016 | 27208991 |
| antagonistic donor density effect conserved in multiple enterococcal conjugative plasmids. | enterococcus faecalis, a common causative agent of hospital-acquired infections, is resistant to many known antibiotics. its ability to acquire and transfer resistance genes and virulence determinants through conjugative plasmids poses a serious concern for public health. in some cases, induction of transfer of e. faecalis plasmids results from peptide pheromones produced by plasmid-free recipient cells, which are sensed by the plasmid-bearing donor cells. these plasmids generally encode an inhi ... | 2016 | 27208137 |
| exogenous fatty acids protect enterococcus faecalis from daptomycin-induced membrane stress independently of the response regulator liar. | enterococcus faecalis is a commensal bacterium of the gastrointestinal tract that can cause nosocomial infections in immunocompromised humans. the hallmarks of this organism are its ability to survive in a variety of stressful habitats and, in particular, its ability to withstand membrane damage. one strategy used by e. faecalis to protect itself from membrane-damaging agents, including the antibiotic daptomycin, involves incorporation of exogenous fatty acids from bile or serum into the cell me ... | 2016 | 27208105 |