Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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| bacteriological characteristics of arcanobacterium haemolyticum isolated from seven patients with skin and soft-tissue infections. | bacteriological examinations were conducted for seven arcanobacterium haemolyticum strains isolated from elderly patients with skin and soft-tissue infections, such as cellulitis and skin ulcers. streptococcus dysgalactiae or gram-positive cocci were isolated together with a. haemolyticum from all patients. the strains were identified as a. haemolyticum based on their being catalase negative, reverse christie, atkins and munch-petersen (camp) positive and phospholipase d gene positive in respect ... | 2015 | 25666838 |
| prevalence of streptococcus dysgalactiae subsp. equisimilis and s. equi subsp. zooepidemicus in a sample of healthy dogs, cats and horses. | to estimate the prevalence of β-haemolytic lancefield group c streptococci in healthy dogs, cats and horses; to determine if frequent contact with horses was associated with isolation of these species from dogs and cats; and to characterise recovered s. equi subsp. zooepidemicus isolates by multilocus sequence typing. | 2015 | 25695401 |
| characteristics of sheep flocks affected by streptococcus dysgalactiae arthritis. | 2015 | 25724543 | |
| genetic diversity of geographically distinct streptococcus dysgalactiae isolates from fish. | streptococcus dysgalactiae is an emerging pathogen of fish. clinically, infection is characterized by the development of necrotic lesions at the caudal peduncle of infected fishes. the pathogen has been recently isolated from different fish species in many countries. twenty s. dysgalactiae isolates collected from japan, taiwan, malaysia and indonesia were molecularly characterized by biased sinusoidal field gel electrophoresis (bsfge) using smai enzyme, and tuf gene sequencing analysis. dna sequ ... | 2015 | 25750757 |
| group c streptococcus dysgalactiae subsp. equisimilis in south-east brazil: genetic diversity, resistance profile and the first report of human and equine isolates belonging to the same multilocus sequence typing lineage. | streptococcus dysgalactiae subsp. equisimilis (sdse) isolates are the most common group c streptococci in humans and reports of invasive infections associated with sdse have been increasing. molecular epidemiology studies are an important strategy to trace the emergence and spread of possible well-fit bacterial pathogens of humans and animals. in this work, we analysed the antimicrobial and clonal profiles of 115 sdse infection and colonization isolates of human and equine origin. pfge revealed ... | 2015 | 25752850 |
| small plasmids in streptococcus dysgalactiae subsp. equisimilis isolated from human infections in southern india and sequence analysis of two novel plasmids. | small plasmids are frequently found in s. pyogenes isolates from human infections in india. streptococcus dysgalactiae subsp. equisimilis (sdse) is a streptococcal subspecies that is genetically similar to s. pyogenes and has a similar ecology. therefore, we determined the distribution of small plasmids in a collection of 254 sdse isolates, comprising 44 different emm-types and emm non-typable strains, from southern india, utilizing an established pcr based method. briefly, 1.2% (n=3) of the iso ... | 2015 | 25769407 |
| visualizing the indefinable: three-dimensional complexity of 'infectious diseases'. | the words 'infection' and 'inflammation' lack specific definitions. here, such words are not defined. instead, the ability to visualize host-microbial interactions was explored. | 2015 | 25875169 |
| synergistic streptococcal phage λsa2 and b30 endolysins kill streptococci in cow milk and in a mouse model of mastitis. | bovine mastitis results in billion dollar losses annually in the usa alone. streptococci are among the most relevant causative agents of this disease. conventional antibiotic therapy is often unsuccessful and contributes to development of antibiotic resistance. bacteriophage endolysins represent a new class of antimicrobials against these bacteria. in this work, we characterized the endolysins (lysins) of the streptococcal phages λsa2 and b30 and evaluated their potential as anti-mastitis agents ... | 2015 | 25895090 |
| phenotypic antimicrobial susceptibility and occurrence of selected resistance genes in gram-positive mastitis pathogens isolated from wisconsin dairy cows. | in the united states, few intramammary antimicrobials exist that are approved for treatment of bovine mastitis; thus, ensuring judicious use of these products is a priority. the objectives of this study were to determine phenotypic susceptibility and presence of selected antimicrobial resistance genes from staphylococci, streptococci, and streptococcal-like organisms recovered from cases of clinical mastitis occurring in cows on large wisconsin farms. staphylococcus aureus (n=35 from 19 herds), ... | 2015 | 25912858 |
| identification of a conserved b-cell epitope on the gapc protein of streptococcus dysgalactiae. | streptococcus dysgalactiae (s. dysgalactia) gapc is a highly conserved surface dehydrogenase among the streptococcus spp., which is responsible for inducing protective antibody immune responses in animals. however, the b-cell epitope of s. dysgalactia gapc have not been well characterized. in this study, a monoclonal antibody 1f2 (mab1f2) against s. dysgalactiae gapc was generated by the hybridoma technique and used to screen a phage-displayed 12-mer random peptide library (ph.d.-12) for mapping ... | 2015 | 25936577 |
| matrix-assisted laser desorption/ionization-time of flight mass spectrometry identification of large colony beta-hemolytic streptococci containing lancefield groups a, c, and g. | the aim of this study was to investigate whether large colony beta-hemolytic streptococci containing lancefield groups a, c, and g can be adequately identified using matrix-assisted laser desorption/ionization-time of flight mass spectrometry (maldi-tof). previous studies show varying results, with an identification rate from below 50% to 100%. | 2015 | 25960250 |
| development of primer sets for loop-mediated isothermal amplification that enables rapid and specific detection of streptococcus dysgalactiae, streptococcus uberis and streptococcus agalactiae. | streptococcus dysgalactiae, streptococcus uberis and streptococcus agalactiae are the three main pathogens causing bovine mastitis, with great losses to the dairy industry. rapid and specific loop-mediated isothermal amplification methods (lamp) for identification and differentiation of these three pathogens are not available. with the 16s rrna gene and 16s-23s rrna intergenic spacers as targets, four sets of lamp primers were designed for identification and differentiation of s. dysgalactiae, s ... | 2015 | 26016433 |
| seropositivity for antibodies to drs-g, a virulence factor from streptococcus dysgalactiae subsp. equisimilis, is an independent risk factor for poststreptococcus glomerulonephritis and chronic kidney disease in mumbai, india. | the disease spectrum caused by streptococcus dysgalactiae subsp. equisimilis resembles that of s. pyogenes (group a streptococcus [gas]). these two bacterial species are closely related and possess many common virulence characteristics. while some gas strains express virulence factors called streptococcal inhibitor of complement (sic) and distantly related to sic (drs), some s. dysgalactiae subsp. equisimilis isolates express an orthologue of drs, which is referred to as drs-g. we reported previ ... | 2015 | 26084513 |
| renal embolism as a primary manifestation of streptococcus dysgalactiae subspecies equisimilis endocarditis in a patient with chronic aortic dissection. | we report a case of renal embolism as an initial manifestation of streptococcus dysgalactiae subspecies equisimilis (sdse) endocarditis in a patient with chronic aortic dissection. a 37-year-old man who underwent total aortic arch replacement owing to aortic dissection, presented with a 3-h history of fever, chills, and acute right-sided flank pain. the endocarditis affected the native aortic valve and was complicated by a renal embolism. blood culture results were positive for sdse. intravenous ... | 2015 | 26110298 |
| susceptibility to antimicrobials of mastitis-causing staphylococcus aureus, streptococcus uberis and str. dysgalactiae from new zealand and the usa as assessed by the disk diffusion test. | to compare the antimicrobial susceptibility patterns of three common mastitis pathogens (staphylococcus aureus, streptococcus uberis and str. dysgalactiae) isolated from milk samples from new zealand and the usa. | 2015 | 26113347 |
| the neutrophil function and lymphocyte profile of milk from bovine mammary glands infected with streptococcus dysgalactiae. | streptococcus dysgalactiae is a bacterium that accounts for a notable proportion of both clinical and subclinical intramammary infections (imis). thus, the present study explores the function of milk neutrophils and the lymphocyte profile in mammary glands naturally infected with streptococcus dysgalactiae. here, we used 32 culture-negative control quarters from eight clinically healthy dairy cows with low somatic cell counts and 13 s. dysgalactiae-infected quarters from six dairy cows. using fl ... | 2015 | 26119656 |
| identification of a conserved linear b-cell epitope of streptococcus dysgalactiae gapc protein by screening phage-displayed random peptide library. | the gapc of streptococcus dysgalactiae (s. dysgalactiae) is a highly conserved surface protein that can induce protective humoral immune response in animals. however, b-cell epitopes on the s. dysgalactiae gapc have not been well identified. in this study, a monoclonal antibody (mab5b7) against the gapc1-150 protein was prepared. after passive transfer, mab5b7 could partially protect mice against s. dysgalactiae infection. eleven positive phage clones recognized by mab5b7 were identified by scre ... | 2015 | 26121648 |
| synthesis and antibacterial activity of novel pleuromutilin derivatives. | in this study we describe the design, synthesis, and antibacterial activity of novel pleuromutilin analogs. a series of new compounds containing piperazine and alkylamino or arylamino groups was synthesized. the new compounds were characterized via (1)h-nmr, (13)c-nmr, fourier transform (ft)-ir and ms, and were further evaluated for their in vitro activity against seven gram-positive, and one gram-negative, pathogens. antibacterial data revealed that all compounds exhibited moderate to good anti ... | 2015 | 26133714 |
| influence of intramammary infection of a single gland in dairy cows on the cow's milk quality. | intramammary infection (imi), comprises a group of costly diseases affecting dairy animals worldwide. many dairy parlours are equipped with on-line computerised data acquisition systems designed to detect imi. however, the data collected is related to the cow level, therefore the contribution of infected glands to the recorded parameters may be over estimated. the present study aimed at evaluating the influence of single gland imi by different bacteria species on the cow's overall milk quality. ... | 2015 | 26134490 |
| toxic shock syndrome: an unusual organism. | streptococcal toxic shock syndrome (stss) is a rapidly fatal disease causing hypotension with multiorgan dysfunction (mods) early in the course of infection, which by definition is caused by group a streptococcus (gas). in this report, a case of toxic shock-like syndrome (tsls) in which the causative organism was not a gas was described. | 2015 | 26244694 |
| a rare case of spontaneous acute bacterial arthritis of the glenohumeral joint attributed to streptococcus dysgalactiae subsp. equisimilis. | 2017 | 26288541 | |
| in vitro photoinactivation of bovine mastitis related pathogens. | bovine mastitis is considered the most important disease of worldwide dairy industry. treatment of this disease is based on the application intramammary antibiotic, which favors an increase in the number of resistant bacteria in the last decade. photodynamic inactivation (pdi) has been investigated in different areas of health sciences, and has shown great potential for inactivating different pathogens, without any selection of resistant microorganisms. the objective of this study was to investi ... | 2016 | 26315923 |
| expression, genetic localization and phylogenic analysis of naplr in piscine streptococcus dysgalactiae subspecies dysgalactiae isolates and their patterns of adherence. | streptococcus dysgalactiae, the long recognized mammalian pathogen, has currently received a major concern regarding fish bacterial infection. adhesion to host epithelial cells and the presence of wall-associated plasminogen binding proteins are prerequisites to streptococcus infection. this is the first study of the occurrence of nephritis-associated plasminogen-binding receptor (naplr) and α-enolase genes in piscine s. dysgalactiae subspecies dysgalactiae (sdsd) isolates. further characterizat ... | 2015 | 26425363 |
| draft genome sequences of four genetically distinct human isolates of streptococcus dysgalactiae subsp. equisimilis. | β-hemolytic group c and group g streptococci (gcs-ggs; streptococcus dysgalactiae subsp. equisimilis) emerged as human pathogens in the late 1970s. we report here the draft genome sequences of four genetically distinct human strains of gcs-ggs isolated between the 1960s and 1980s. comparative analysis of these genomes may provide a deeper understanding of gcs-ggs genome and virulence evolution. | 2015 | 26430051 |
| prevalence of emm types and antimicrobial susceptibility of streptococcus dysgalactiae subsp. equisimilis in austria. | an increase of severe infections caused by streptococcus dysgalactiae subsp. equisimilis (sdse) similar to infections caused by streptococcus pyogenes has been reported over the last years. little is known about infections with sdse in austria. therefore, we investigated a collection of 113 sdse invasive and non-invasive isolates from different infection sites and type of infections as well as patients' characteristics. | 2015 | 26507866 |
| infectious cause of death determination using minimally invasive autopsies in developing countries. | in developing countries, the knowledge of the microorganisms causing fatal infections is critical and could help designing and implementing more effective preventive interventions and treatment guidelines. we aimed to develop and validate protocols for microbiological analysis in post-mortem samples obtained during minimally invasive autopsy (mia) procedures and to assess their performance. thirty mias performed in adults at maputo central hospital in southern mozambique were included in the ana ... | 2016 | 26508103 |
| sharing a microbe with man's best friend: a case of canine streptococcal infection in a diabetic patient. | we report a case of a diabetic patient with an infected leg wound leading to septicemia and abscess formation in the contra-lateral leg due to streptococcus canis. this organism belongs to the lancefield group g and is more commonly found in dogs. it is often mistaken for streptococcus dysgalactiae which is a human strain of streptococci. infections in humans are not common and usually involve infected wounds or ulcers and the surrounding soft tissue. in most reported cases, patients had close c ... | 2015 | 26556125 |
| assessment and characterization of biofilm formation among human isolates of streptococcus dysgalactiae subsp. equisimilis. | the capacity to form biofilm is considered a protective mechanism that allows the bacteria to survive and proliferate in hostile environments, facilitating the maintenance of the infectious process. recently, biofilm has become a topic of interest in the study of the human pathogen group a streptococcus (gas). although gas has not been associated with infection on medical implants, the presence of microcolonies embedded in an extracellular matrix on infected tissues has been reported. despite th ... | 2015 | 26558847 |
| increased cytotoxicity and streptolysin o activity in group g streptococcal strains causing invasive tissue infections. | streptococcus dysgalactiae subsp. equisimilis (sdse) has emerged as an important cause of severe skin and soft tissue infections, but little is known of the pathogenic mechanisms underlying tissue pathology. patient samples and a collection of invasive and non-invasive group g sdse strains (n = 69) were analyzed with respect to virulence factor expression and cytotoxic or inflammatory effects on human cells and 3d skin tissue models. sdse strains efficiently infected the 3d-skin model and severe ... | 2015 | 26601609 |
| infection of human keratinocytes by streptococcus dysgalactiae subspecies dysgalactiae isolated from milk of the bovine udder. | streptococcus dysgalactiae subsp. dysgalactiae (sdsd) are considered exclusive animal pathogens; however, a putative zoonotic upper limb cellulitis, a prosthetic joint infection and an infective endocarditis were described in humans. to unravel if bovine sdsd isolates are able to infect human cells, the adherence and internalization to human primary keratinocytes of two bovine sdsd strains isolated from milk collected from udder were analyzed. bacterial adhesion assays and confocal microscopy in ... | 2016 | 26655883 |
| identification and characterization of cd4⁺ t-cell epitopes on gapc protein of streptococcus dysgalactiae. | the gapc protein is highly conserved surface dehydrogenase among streptococcus dysgalactiae (s. dysgalactiae) and is shown to be involved in bacterial virulence. immunization of gapc protein can induce specific cd4(+) t-cell immune responses and protect against s. dysgalactiae infection. however, there are no studies to identify immunodominant cd4(+) t-cell epitopes on gapc protein. in this study, in silico mhc affinity measurement method was firstly used to predict potential cd4(+) t-cell epito ... | 2016 | 26657721 |
| glyceradehyde-3-phosphate dehydrogenase as a suitable vaccine candidate for protection against bacterial and parasitic diseases. | the enzyme glyceraldehyde-3-p-dehydrogenase (gapdh) has been identified as having other properties in addition to its key role in glycolysis. the ability of gapdh to bind to numerous extracellular matrices, modulation of host-immune responses, a role in virulence and surface location has prompted numerous investigators to postulate that gapdh may be a good vaccine candidate for protection against numerous pathogens. although immune responses against gapdh have been described for many microorgani ... | 2016 | 26686572 |
| transcriptome analysis of soiny mullet (liza haematocheila) spleen in response to streptococcus dysgalactiae. | soiny mullet (liza haematocheila) is becoming an economically important aquaculture mugilid species in china and other asian countries. however, increasing incidences of bacterial pathogenic diseases has greatly hampered the production of the soiny mullet. deeper understanding of the soiny mullet immune system and its related genes in response to bacterial infections are necessary for disease control in this species. in this study, the transcriptomic profile of spleen from soiny mullet challenge ... | 2016 | 26707943 |
| comparative erythromycin and tylosin susceptibility testing of streptococci from bovine mastitis. | tylosin, a 16-membered macrolide, is - besides other indications - used for the treatment of bovine mastitis. so far, there is only limited information available on the tylosin susceptibility of streptococci isolated from mastitis. the aim of the present study was to comparatively investigate 303 streptococci from bovine mastitis, including 101 streptococcus agalactiae, 100 streptococcus dysgalactiae and 102 streptococcus uberis, for their tylosin and erythromycin susceptibility by broth microdi ... | 2016 | 26732695 |
| etiology of cellulitis and clinical prediction of streptococcal disease: a prospective study. | background. the importance of bacteria other than group a streptococci (gas) in different clinical presentations of cellulitis is unclear, commonly leading to treatment with broad-spectrum antibiotics. the aim of this study was to describe the etiological and clinical spectrum of cellulitis and identify clinical features predicting streptococcal etiology. methods. we prospectively enrolled 216 patients hospitalized with cellulitis. clinical details were registered. bacterial culture was perfor ... | 2016 | 26734653 |
| molecular characterization of invasive streptococcus dysgalactiae subsp. equisimilis, japan. | we collected β-hemolytic streptococci (1,611 isolates) from patients with invasive streptococcal infections in japan during april 2010-march 2013. streptococcus dysgalactiae subsp. equisimilis (sdse) was most common (n = 693); 99% of patients with sdse infections were elderly (mean age 75 years, sd ±15 years). we aimed to clarify molecular and epidemiologic characteristics of sdse isolates and features of patient infections. bacteremia with no identified focus of origin and cellulitis were the m ... | 2016 | 26760778 |
| severe invasive streptococcal infection by streptococcus pyogenes and streptococcus dysgalactiae subsp. equisimilis. | streptococcus pyogenes, a group a streptococcus (gas), has been recognized as the causative pathogen in patients with severe invasive streptococcal infection with or without necrotizing fasciitis. in recent epidemiological studies, streptococcus dysgalactiae subsp. equisimilis (sdse) has been isolated from severe invasive streptococcal infection. complete genome sequence showed that sdse is the closest bacterial species to gas, with approximately 70% of genome coverage. sdse, however, lacks seve ... | 2016 | 26762200 |
| udder infections with staphylococcus aureus, streptococcus dysgalactiae, and streptococcus uberis at calving in dairy herds with suboptimal udder health. | udder infections with staphylococcus aureus, streptococcus dysgalactiae, and streptococcus uberis are common causes of bovine mastitis. to study these pathogens in early lactation, a 12-mo longitudinal, observational study was carried out in 13 herds with suboptimal udder health. the aims of the study were to investigate the occurrence of these pathogens and to identify if presence of the 3 pathogens, and of genotypes within the pathogens, differed with respect to herd, season, and parity. quart ... | 2016 | 26805990 |
| genome sequence and virulence factors of a group g streptococcus dysgalactiae subsp. equisimilis strain with a new element carrying erm(b). | a streptococcus dysgalactiae subsp. equisimilis (sdse) strain wchsdse-1, which caused an outbreak of tonsillopharyngitis among healthcare workers in china, was subjected to genome sequencing and analysis. wchsdse-1 belongs to the lancefield group g, emm type stg211.1 and sequence type 44. wchsdse-1 has virulence factors for adherence, impairing the recruitment of neutrophils to infection sites and toxins including streptolysins o and s and exotoxin g. wchsdse-1 has a 45.4-kb element resembling a ... | 2016 | 26843282 |
| recurrent bacteremia with streptococcus dysgalactiae: a case-control study. | beta-hemolytic streptococci of groups c and g, designated as streptococcus dysgalactiae (sd), can cause severe and recurring invasive infections. in this case-control study, we aimed to identify clinical and molecular risk factors for recurrence of sd bacteremia. twenty-two cases of recurrent sd bacteremia were identified, and median time between episodes was 6 months. the most frequent clinical manifestation was skin and soft tissue infection. cases and 92 controls, with single-episode sd bacte ... | 2016 | 26906192 |
| a highly susceptible cd46 transgenic mouse model of subcutaneous infection with streptococcus dysgalactiae subspecies equisimilis. | the streptococcus dysgalactiae subspecies equisimilis (sdse) possesses clinical similarities to group a streptococcus (gas) and has recently been recognized as a causative pathogen of life-threatening streptococcal infections. human membrane cofactor protein (cd46), a complement regulatory protein ubiquitously expressed on every cell type except for erythrocytes, has been implicated as a receptor for human-specific pathogens including gas. in the present report, sdse strain ggs_124 was isolated ... | 2016 | 26908231 |
| molecular characterization and antibiotic resistance of clinical streptococcus dysgalactiae subsp. equisimilis in beijing, china. | streptococcus dysgalactiae subsp. equisimilis (sdse) is presently considered as a human pathogen associated with clinical infection. we characterized 56 sdse isolates collected from two tertiary hospitals in beijing, china. sixteen distinct emm types/subtypes were detected, dominated by stg245.0 (32.1%), stg652.0 (10.7%), stg6.1 (10.7%) and stg485.0 (10.7%), and a novel stg840.0 variant type was identified. all isolates possessed virulence genes of saga and scpa, and most carried slo (98.2%), sk ... | 2016 | 26925701 |
| proposal for agar disk diffusion interpretive criteria for susceptibility testing of bovine mastitis pathogens using cefoperazone 30μg disks. | cefoperazone is a third generation cephalosporin which is commonly used for bovine mastitis therapy. bacterial pathogens involved in bovine mastitis are frequently tested for their susceptibility to cefoperazone. so far, the cefoperazone susceptibility testing using 30μg disks has been hampered by the lack of quality control (qc) ranges as well as the lack of interpretive criteria. in 2014, qc ranges for 30 μg cefoperazone disks have been established for staphylococcus aureus atcc(®) 25923 and e ... | 2017 | 26987627 |
| genetic diversity in streptococcus dysgalactiae subsp. equisimilis isolates from patients with invasive and noninvasive infections in a japanese university hospital (2014-2015). | streptococcus dysgalactiae subsp. equisimilis (sdse) isolates with β-hemolysis and carbohydrate groups g or c are increasingly recovered from invasive infections in japan. the aim of this study was to determine the epidemiological characteristics of sdse isolates circulating locally among patients with invasive and noninvasive infections. we selected groups g/c β-hemolytic streptococci from a repository at the clinical laboratory of kitasato university medical center, from may 2014 through april ... | 2017 | 27000456 |
| lactoferrin affects the adherence and invasion of streptococcus dysgalactiae ssp. dysgalactiae in mammary epithelial cells. | streptococcus dysgalactiae ssp. dysgalactiae is an important causative agent of bovine mastitis worldwide. lactoferrin is an innate immune protein that is associated with many functions including immunomodulatory, antiproliferative, and antimicrobial properties. this study aimed to investigate the interactions between lactoferrin and a clinical bovine mastitis isolate, strep. dysgalactiae ssp. dysgalactiae dpc5345. initially a deliberate in vivo bovine intramammary challenge was performed with s ... | 2016 | 27016824 |
| short communication: n-acetylcysteine-mediated modulation of antibiotic susceptibility of bovine mastitis pathogens. | the aim of this study was to investigate the effects of n-acetylcysteine (nac) on antibiotic susceptibility of bovine mastitis pathogens including staphylococcus aureus, streptococcus dysgalactiae, escherichia coli, and streptococcus agalactiae. minimum inhibitory concentrations (mic) were tested by the agar-based e-test method. the presence of 10mm nac reduced the mic of penicillin and ampicillin but enhanced the mic of erythromycin and ciprofloxacin for all of the strains. in addition, nac-med ... | 2016 | 27016837 |
| hygienic characteristics and microbiological hazard identification in horse and donkey raw milk. | today the interest toward horse (equus caballus) and donkey (equus asinus) milk for human consumption is receiving a renewed attention because of its particular composition, hypoallergenicity, and nutraceutical properties. the realistic perspective of global use of this aliment in balanced diets, especially for infancy and geriatrics, poses the need for a more in depth knowledge on milk hygiene and on the health status of dairy animals, as a prerequisite of consumers' safety. the aim of this pap ... | 2017 | 27033528 |
| synthesis of an aminooxy derivative of the tetrasaccharide repeating unit of streptococcus dysgalactiae 2023 polysaccharide for a ps a1 conjugate vaccine. | a highly efficient and stereocontrolled synthesis of an aminooxy derivative of the tetrasaccharide repeating unit of a rhamnose-rich polysaccharide isolated from the cell envelop of bovine mastitis streptococcus dysgalactiae 2023 is reported for the first time. the synthesis was accomplished utilizing a stereoselective and convergent [2 + 2] glycosylation strategy inclusive of a disaccharide schmidt donor and an inclusive rhamnose disaccharide acceptor. the synthetic aminooxy tetrasaccharide was ... | 2016 | 27149417 |
| prevalence of bovine mastitis pathogens in bulk tank milk in china. | the objectives of this study were to estimate the herd prevalence of major mastitis pathogens in bulk tank milk (btm) in china dairy herds, to determine the relationship between the presence of mastitis pathogens and bulk tank milk somatic cell counts (btscc), and to investigate the impact of different dairy cattle farming modes and region on bacterial species. btm samples collected from 894 dairy herds in china were examined for the presence of mastitis pathogens. the flinders technology associ ... | 2016 | 27187065 |
| endosd: an igg glycan hydrolyzing enzyme in streptococcus dysgalactiae subspecies dysgalactiae. | the aim of this study was to identify and characterize endos-like enzymes in streptococcus dysgalactiae subspecies dysgalactiae (sdsd). | 2016 | 27200457 |
| antimicrobial susceptibility and genetic relationships among streptococcus dysgalactiae subsp. equisimilis isolates in rio de janeiro. | streptococcus dysgalactiae subsp. equisimilis (sdse) has been increasingly associated with several infectious diseases, ranging from pharyngitis to life-threatening conditions, such as necrotizing fasciitis and streptococcal toxic shock syndrome. however, its molecular epidemiology in some geographical areas remains unclear. | 2016 | 27301015 |
| cloning and expression of β-defensin from soiny mullet (liza haematocheila), with insights of its antibacterial mechanism. | beta-defensins are important part of innate immunity of fish, which are the first defense line against invading pathogens. in this study, the β-defensin (lhβ-defensin) gene was cloned from spleen tissue of soiny mullet (liza haematocheila). lhβ-defensin cdna was 747 bp in length, encoding 63 amino acids. sequence alignment revealed that lhβ-defensin contained six conserved cysteine residues and shared 97.5% sequence identities with grouper (epinephelus coioides) β-defensin. realtime pcr revealed ... | 2016 | 27322675 |
| first molecular evidence of intrauterine and surgical-site infections caused by streptococcus dysgalactiae subsp. equisimilis. | s. dysgalactiae subsp. equisimilis (sdse) is infrequently associated with maternal infections during delivery in pregnant women. a rare case is presented of a woman with intrauterine infection and surgical-site infection due to sdse after cesarean section, which had colonized her genital tract and, via the ascending pathway, reached her intact fetal membrane. all isolates were identified as streptococcus lancefield group g, and their emm genes that coded m protein belonged to stg6.1. the isolate ... | 2016 | 27367018 |
| use of rumination and activity monitoring for the identification of dairy cows with health disorders: part ii. mastitis. | the objectives of this study were to evaluate (1) the performance of an automated health-monitoring system (ahms) to identify cows with mastitis based on an alert system (health index score, his) that combines rumination time and physical activity; (2) the number of days between the first his alert and clinical diagnosis (cd) of mastitis by farm personnel; and (3) the daily rumination time, physical activity, and his patterns around cd. holstein cows (n=1,121; 451 nulliparous and 670 multiparous ... | 2016 | 27372584 |
| toxic shock syndrome: an unusual organism. | streptococcal toxic shock syndrome is a rapidly fatal disease causing hypotension with multi organ dysfunction (mods) early in the course of infection, which by definition is caused by group a streptococcus (gas). we describe a case of toxic shock like syndrome (tsls) in which the causative organism was not a gas. a 71-year-old woman with hepatitis c and primary biliary cirrhosis had sudden onset of slurred speech and left arm and facial numbness. she had bilateral erythematous macular rash pres ... | 2016 | 27432040 |
| recurrent sdse bacteraemia resulting in streptococcal toxic shock syndrome in a patient with noonan syndrome. | a 19-year-old man with chronic lymphoedema due to noonan syndrome presented at our hospital with septic shock and pain in his lower leg. blood cultures were positive for streptococcus dysgalactiae subsp equisimilis (sdse), resulting in a diagnosis of cellulitis with toxic involvement. he was treated with ampicillin for 3 weeks. although he did well for 6 weeks, septic shock recurred. blood culture again revealed sdse, with the strain being identical to the first episode, suggesting that this inf ... | 2016 | 27485878 |
| streptococcus dysgalactiae subsp. equisimilis isolated from infections in dogs and humans: are current subspecies identification criteria accurate? | streptococcus dysgalactiae is a pyogenic species pathogenic both for humans and animals. until recently, it has been considered an exclusive animal pathogen causing infections in wild as well as domestic animals. currently, human infections are being reported with increasing frequency, and their clinical picture is often similar to the ones caused by streptococcus pyogenes. due to the fact that s. dysgalactiae is a heterogeneous species, it was divided into two subspecies: s. dysgalactiae subsp. ... | 2016 | 27502064 |
| beta-hemolytic streptococcus dysgalactiae strains isolated from horses are a genetically distinct population within the streptococcus dysgalactiae taxon. | the pathogenic role of beta-hemolytic streptococcus dysgalactiae in the equine host is increasingly recognized. a collection of 108 lancefield group c (n = 96) or l (n = 12) horse isolates recovered in the united states and in three european countries presented multilocus sequence typing (mlst) alleles, sequence types and emm types (only 56% of the isolates could be emm typed) that were, with few exceptions, distinct from those previously found in human streptococcus dysgalactiae subsp. equisimi ... | 2016 | 27530432 |
| molecular and antimicrobial susceptibility profiling of streptococcus dysgalactiae isolated from swine. | streptococcus dysgalactiae subspecies equisimilis and dysgalactiae were isolated from swine clinical specimens. the subspecies equisimilis presented 2 clonal patterns with 85% genetic similarity, whereas subspecies dysgalactiae presented distinct band pattern with less than 80% similarity with equisimilis genotypes. isolates presented high mic values to tetracyclines, danofloxacin, spectinomycin, tiamulin, and clindamycin. | 2016 | 27539863 |
| description and characterization of a penicillin-resistant streptococcus dysgalactiae subsp. equisimilis clone isolated from blood in three epidemiologically linked patients. | during a 27 month period, we detected four incidents of penicillin-resistant (pr) streptococcus dysgalactiae subsp. equisimilis (sdse) isolated from blood cultures of three patients. | 2016 | 27585966 |
| refractory toxic shock-like syndrome from streptococcus dysgalactiae ssp. equisimilis and intravenous immunoglobulin as salvage therapy: a case series. | infections from streptococcus dysgalactiae ssp. equisimilis (sdse) can cause a wide variety of infections, ranging from mild cellulitis to invasive disease, such as endocarditis and streptococcal toxic shock-like syndrome (tsls). despite prompt and appropriate antibiotics, mortality rates associated with shock have remained exceedingly high, prompting the need for adjunctive therapy. ivig has been proposed as a possible adjunct, given its ability to neutralize a wide variety of superantigens and ... | 2016 | 27597908 |
| throat culture positivity rate and antibiotic susceptibility pattern of beta-hemolytic streptococci in children on secondary prophylaxis for rheumatic heart disease. | among children diagnosed to have chronic rheumatic valvular heart disease (rhd) in ethiopia, many have been observed to develop recurrence of rheumatic fever (rf) despite secondary prophylaxis. this study determined the throat culture positivity rate and drug susceptibility pattern of beta hemolytic streptococci (bhs) isolated from children attending a specialized cardiac clinic in ethiopia. | 2016 | 27663649 |
| preparation, characterization, and pharmacokinetics of tilmicosin- and florfenicol-loaded hydrogenated castor oil-solid lipid nanoparticles. | to effectively control bovine mastitis, tilmicosin (til)- and florfenicol (ff)-loaded solid lipid nanoparticles (sln) with hydrogenated castor oil (hco) were prepared by a hot homogenization and ultrasonication method. in vitro antibacterial activity, properties, and pharmacokinetics of the til-ff-sln were studied. the results demonstrated that til and ff had a synergistic or additive antibacterial activity against streptococcus dysgalactiae, streptococcus uberis, and streptococcus agalactiae. t ... | 2016 | 27687707 |
| antimicrobial susceptibility patterns of environmental streptococci recovered from bovine milk samples in the maritime provinces of canada. | determination of antimicrobial susceptibility of bovine mastitis pathogens is important for guiding antimicrobial treatment decisions and for the detection of emerging resistance. environmental streptococci are ubiquitous in the farm environment and are a frequent cause of mastitis in dairy cows. the aim of the study was to determine patterns of antimicrobial susceptibility among species of environmental streptococci isolated from dairy cows in the maritime provinces of canada. the collection co ... | 2016 | 27695696 |
| survival of streptococcus suis, streptococcus dysgalactiae and trueperella pyogenes in dry-cured iberian pork shoulders and loins. | dry-cured hams, shoulders and loins of iberian pigs are highly appreciated in national and international markets. salting, additive addition and dehydration are the main strategies to produce these ready-to-eat products. although the dry curing process is known to reduce the load of well-known food borne pathogens, studies evaluating the viability of other microorganisms in contaminated pork have not been performed. in this work, the efficacy of the dry curing process to eliminate three swine pa ... | 2017 | 27697171 |
| species and emm-type distribution of group c and g streptococci from different sites of isolation. | beta-haemolytic streptococci of groups c (gcs) and g (ggs) from human infections typically belong to streptococcus dysgalactiae and are important human pathogens. among ggs (183 isolates), several emm-types were identified without significant differences between different sites of isolation. for gcs (79 isolates), the type-distribution was markedly different and more restricted. | 2016 | 27712926 |
| temporal trends of β-haemolytic streptococcal osteoarticular infections in western norway. | beta-haemolytic streptococci are important contributors to the global burden of osteoarticular infections (oai). knowledge on the disease traits specific for streptococcal oai, however, remains scarce. we wished to explore temporal trends of oai caused by group a streptococci (gas), group b streptococci (gbs) and group c and g streptococci (gcgs), and furthermore, to describe the associated host and pathogen characteristics. | 2016 | 27716100 |
| kinetic controlled tag-catcher interactions for directed covalent protein assembly. | over the last few years, a number of different protein assembly strategies have been developed, greatly expanding the toolbox for controlling macromolecular assembly. one of the most promising developments is a rapid protein ligation approach using a short polypeptide spytag and its partner, spycatcher derived from streptococcus pyogenes fibronectin-binding protein, fbab. to extend this technology, we have engineered and characterized a new tag-catcher pair from a related fibronectin-binding pro ... | 2016 | 27783674 |
| prevalence of bovine milk pathogens in azorean pastures: mobile versus fixed milking machines. | the aims of the present study were (1) to evaluate the influence of using mobile (n=47) or fixed (n=45) milking machines in azorean herds on the apparent prevalence of several milk pathogens in bulk tank milk (btm) and (2) to determine whether separated subclinical mastitic cows can serve, in real time, as predictors of milk pathogen prevalence for the remaining animals at the herd level. the use of a mobile or fixed milking machine influenced (p≤0.05) the prevalence of staphylococcus aureus (72 ... | 2016 | 27843558 |
| sensitivity and specificity of pcr analysis and bacteriological culture of milk samples for identification of intramammary infections in dairy cows using latent class analysis. | real-time pcr analysis of milk samples is a fast method to identify intramammary infections (imi) in dairy cows, and has the potential to be used for routine analysis of test milking composite milk samples. however, the results of the pcr analysis can be difficult to interpret. the objective of this study was to compare the sensitivity (se) and specificity (sp) of pcr analysis of composite milk samples, and conventional bacteriological culturing (bc) of quarter milk samples, when used to identif ... | 2016 | 27931924 |
| prevalence of macrolide-lincosamide resistance and multidrug resistance phenotypes in streptococcal isolates causing infections in european hospitals: evaluation of the in vitro activity of oritavancin and comparator agents. | the aim of this study was to evaluate the prevalence of resistance to erythromycin alone (m) and to erythromycin and clindamycin (cmlsb) as well as multidrug resistance (mdr) phenotypes (resistance to at least three classes of drugs) among clinical enterococci from european countries and adjacent geographic regions. the in vitro activity of oritavancin against these isolates was also evaluated. a total of 2569 streptococci collected from 12 european countries as well as russia, turkey and israel ... | 2017 | 27939809 |
| welcome to volume 12 of the journal future microbiology. | 2017 | 27997247 | |
| identification of group g streptococci isolates from companion animals in japan and their antimicrobial resistance. | this study determined species-level identification and antimicrobial resistance (amr) properties in group g streptococci (ggs) isolates from companion animals in japan. strains were isolated from sterile/non-sterile specimens of 72 animals with clinical symptoms or signs in april-may, 2015. we identified them based on 16s rrna sequencing, mass spectrometry (ms), and an automated method based on their biochemical properties. antimicrobial susceptibility was determined with broth microdilution met ... | 2016 | 28003600 |
| management of acute hematogenous infection following total knee arthroplasty: a case series of 11 patients. | acute hematogenous infection is a devastating complication that can occur after total knee arthroplasty (tka). the best strategies for management of this infection remain controversial. two-stage revision has been well described as the gold standard for the management of chronic late infections. however, there is a paucity of information presently available on the management and outcomes of patients treated for acute hematogenous infections. the purpose of the present study was to report the out ... | 2016 | 28032700 |
| pulsed xenon flash treatment inactivates bacteria in apheresis platelet concentrates while preserving in vitro quality and functionality. | pulsed xenon (xe) flash without any photoreactive compounds has been shown to inactivate a type of bacteria spiked into platelet (plt) suspension in plasma, but enhanced the plt storage lesion (psl). predicting reduction of psl with increasing bactericidal ability, pulsed xe flash was filtered through a band-stop filter, which excluded ultraviolet (uv)a, uvb, and visible light. | 2017 | 28084008 |
| multiplex pcr-based identification of streptococcus canis, streptococcus zooepidemicus and streptococcus dysgalactiae subspecies from dogs. | streptococcus canis (s. canis), streptococcus equi subspecies zooepidemicus (s. zooepidemicus) and streptococcus dysgalactiae subspecies (s. dysgalactiae subspecies) are β-haemolytic gram positive bacteria infecting animals and humans. s. canis and s. zooepidemicus are considered as two of the major zoonotic species of streptococcus, while more research is needed on s. dysgalactiae subspecies bacteria. in this work, a multiplex-pcr protocol was tested on strains and clinical samples to detect s. ... | 2017 | 28131378 |
| non-culture-based identification of mastitis-causing bacteria by maldi-tof mass spectrometry. | the purpose of this study was to evaluate the detection limit of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof ms) for direct identification, without previous microbiological culture, of bovine mastitis-causing bacteria from milk samples. milk samples (n = 15) were experimentally contaminated with staphylococcus aureus, streptococcus uberis, streptococcus agalactiae, streptococcus dysgalactiae, and escherichia coli to have bacterial counts ranging from 1 ... | 2017 | 28161160 |
| infective endocarditis and infected aneurysm caused by streptococcus dysgalactiae subsp. equisimilis: a case report. | endocarditis caused by streptococcus dysgalactiae subsp. equisimilis (sdse) is rare. infected aneurysm is one of the most serious complications of infective endocarditis. however, no reports have described sdse-related infected aneurysm. we herein report a successfully treated case of sdse-associated infective endocarditis with an infected aneurysm. | 2017 | 28174648 |
| evaluation of microbiological, cellular and risk factors associated with subclinical mastitis in female buffaloes. | this study aimed to evaluate the microbiological and cellular milk profile for the diagnosis of subclinical mastitis in female buffaloes and to assess risk factors for predisposition of the disease. | 2017 | 28183165 |
| recurrent early prosthetic valve endocarditis caused by streptococcus dysgalactiae subspecies equisimilis. | 2017 | 28183423 | |
| potential factors enabling human body colonization by animal streptococcus dysgalactiae subsp. equisimilis strains. | streptococcus dysgalactiae subsp. equisimilis (sdse) is a pyogenic, lancefield c or g streptococcal pathogen. until recently, it has been considered as an exclusive animal pathogen. nowadays, it is responsible for both animal infections in wild animals, pets, and livestock and human infections often clinically similar to the ones caused by group a streptococcus (streptococcus pyogenes). the risk of zoonotic infection is the most significant in people having regular contact with animals, such as ... | 2017 | 28314902 |
| streptokinase production from streptococcus dysgalactiae subsp. equisimilis sk-6 in the presence of surfactants, growth factors and trace elements. | streptokinase is an extracellular protein secreted by various strains of streptococci and is used clinically as an intravenous thrombolytic agent for the treatment of acute myocardial infarction. it is well established that the fibrinolytic activity of streptokinase originates in its ability to activate plasminogen. the present investigation was carried out to determine the extent of streptokinase production by streptococcus dysgalactiae subsp. equisimilis sk-6, in the presence of surfactants, g ... | 2015 | 28324574 |
| molecular characterization of invasive streptococcus dysgalactiae subsp. equisimilis. multicenter study: argentina 2011-2012. | streptococcus dysgalactiae subsp. equisimilis (sdse) has virulence factors similar to those of streptococcus pyogenes. therefore, it causes pharyngitis and severe infections indistinguishable from those caused by the classic pathogen. the objectives of this study were: to know the prevalence of sdse invasive infections in argentina, to study the genetic diversity, to determine the presence of virulence genes, to study antibiotic susceptibility and to detect antibiotic resistance genes. conventio ... | 2017 | 28341023 |
| factors associated with intramammary infection in dairy cows caused by coagulase-negative staphylococci, staphylococcus aureus, streptococcus uberis, streptococcus dysgalactiae, corynebacterium bovis, or escherichia coli. | the aim of this study was to determine risk factors for bovine intramammary infection (imi) associated with the most common bacterial species in finland. large databases of the finnish milk-recording system and results of microbiological analyses of mastitic milk samples from valio ltd. (helsinki, finland) were analyzed. the study group comprised 29,969 cows with imi from 4,173 dairy herds. a cow with a quarter milk sample in which dna of target species was detected in the pathoproof mastitis pc ... | 2017 | 28341052 |
| more bark than bite: comparative studies are needed to determine the importance of canine zoonoses in aboriginal communities. a critical review of published research. | the objective of this review was to identify and critique over forty years of peer-reviewed literature concerned with the transmission of canine zoonoses to aboriginal people and determine the zoonotic organisms documented in dogs in australian aboriginal communities. a systematic literature search of public health, medical and veterinary databases identified 19 articles suitable for critical appraisal. thirteen articles documented the occurrence of recognized zoonotic organisms in dogs in abori ... | 2017 | 28342271 |
| group g streptococcus dysgalactiae subspecies equisimilis, the clinical significance of a rare infection: endocarditis, polyarteritis, septic bursitis and pneumonia with complicated parapneumonic effusion. | 2017 | 28348265 | |
| epidemiological study of common diseases and their risk factors in camels in south punjab, pakistan. | bacteriological study of mastitis along with common blood protozoan diseases were studied in dromedary camels in cholistan, dera ismail khan and rahim yar khan districts in south punjab, pakistan. for this purpose 300 camels were sampled randomly at different common grazing and watering point. for study of blood parasites clinically suspected and apparently healthy camels, 150 each, were sampled. an overall prevalence of 15%and 5% was recorded for trypanosomiasis and anaplasmosis respectively. t ... | 2017 | 28428133 |
| incidence of clinical mastitis and distribution of pathogens on large chinese dairy farms. | knowledge of the incidence of clinical mastitis (cm) and the distribution of pathogens involved is essential for development of prevention and control programs as well as treatment protocols. no country-wide study on the incidence of cm and the distribution of pathogens involved has been conducted in china. core objectives of this study were, therefore, to determine the cumulative incidence of cm and the distribution of pathogens causing cm on large chinese (>500 cows) dairy farms. in addition, ... | 2017 | 28434736 |
| an ecological approach to discover new bioactive extracts and products: the case of extremophile plants. | eight extremophile plants from tunisia were screened to find natural products with benefits in human health. | 2017 | 28444868 |
| prevalence of complement-mediated cell lysis-like gene (sicg) in streptococcus dysgalactiae subsp. equisimilis isolates from japan (2014-2016). | streptococcus dysgalactiae subsp. equisimilis (sdse; a β-hemolytic streptococcus of human or animal origin) infections are emerging worldwide. we evaluated the clonal distribution of complement-mediated cell lysis-like gene (sicg) among sdse isolates from three central prefectures of japan. | 2017 | 28445008 |
| validity of somatic cell count as indicator of pathogen-specific intramammary infections. | the objective of this study was to determine whether somatic cell count (scc) was an effective test, with a sensitivity exceeding 85%, to determine species-specific bacterial infections. in addition, the relation between the scc and various udder pathogen groups was investigated. scc thresholds of greater than 200 000 cells/ml were used in quarter and greater than 150 000 cells/ml in composite milk samples. a retrospective study was conducted on a data set for 89 635 quarter and 345 467 composit ... | 2017 | 28470079 |
| draft genome sequence of streptococcus dysgalactiae subsp. equisimilis strain c161l1 isolated in vellore, india. | streptococcus dysgalactiae subsp. equisimilis belongs to the β-hemolytic group c and g pyogenic group of streptococci. here, we report the draft genome of the s. dysgalactiae subsp. equisimilis strain c161l1 from vellore, a region in southern india with a high incidence rate of s. dysgalactiae subsp. equisimilis infection. this genome is 2.1 mb long, with a 39.82% g+c content, and encodes 2,022 genes. | 2017 | 28495783 |
| septic arthritis due to streptococcus dysgalactiae subspecies equisimilis in a healthy school child. | 2017 | 28505017 | |
| acute bacterial meningitis and systemic abscesses due to streptococcus dysgalactiae subsp. equisimilis infection. | disseminated abscesses due to group g β-hemolytic streptococcus dysgalactiae were observed in a 57-year-old cirrhotic patient with the skin being the putative way of entry for the pathogen. s. dysgalactiae is a rare agent in human infections responsible for acute pyogenic meningitis. the mortality rate associated with s. dysgalactiae bacteraemia and meningitis may be as high as 50%, particularly in the presence of endocarditis or brain abscesses. in our patient, main sites of infections were men ... | 2017 | 28512590 |
| bacteriological etiology and treatment of mastitis in finnish dairy herds. | the finnish dairy herd recording system maintains production and health records of cows and herds. veterinarians and farmers register veterinary treatments in the system. milk samples for microbiological analysis are routinely taken from mastitic cows. the laboratory of the largest dairy company in finland, valio ltd., analyzes most samples using real-time pcr. this study addressed pathogen-specific microbiological data and treatment and culling records, in combination with cow and herd characte ... | 2017 | 28545485 |
| whole-genome sequence analysis of antimicrobial resistance genes in streptococcus uberis and streptococcus dysgalactiae isolates from canadian dairy herds. | the objectives of this study are to determine the occurrence of antimicrobial resistance (amr) genes using whole-genome sequence (wgs) of streptococcus uberis (s. uberis) and streptococcus dysgalactiae (s. dysgalactiae) isolates, recovered from dairy cows in the canadian maritime provinces. a secondary objective included the exploration of the association between phenotypic amr and the genomic characteristics (genome size, guanine-cytosine content, and occurrence of unique gene sequences). initi ... | 2017 | 28589129 |
| identification and expression analysis of two pro-inflammatory cytokines, tnf-α and il-8, in cobia (rachycentron canadum l.) in response to streptococcus dysgalactiae infection. | tumor necrosis factor-alpha (tnf-α) and interleukin-8 (il-8/cxcl8) play pivotal roles in mediating inflammatory responses to invading pathogens. in this study, we identified and analyzed expressions of cobia tnf-α and il-8 during streptococcus dysgalactiae infection. the cloned cdna transcript of cobia tnf-α comprised of 1281 base pairs (bp), with a 774 bp open reading frame (orf) encoding 257 amino acids. the deduced amino acid sequence of cobia tnf-α showed a close relationship (84% similarity ... | 2017 | 28600195 |
| phenotypic and genotypic antimicrobial susceptibility pattern of streptococcus spp. isolated from cases of clinical mastitis in dairy cattle in poland. | mastitis of dairy cattle is one of the most frequently diagnosed diseases worldwide. the main etiological agents of mastitis are bacteria of the genus streptococcus spp., in which several antibiotic resistance mechanisms have been identified. however, detailed studies addressing this problem have not been conducted in northeastern poland. therefore, the aim of our study was to analyze, on phenotypic and genotypic levels, the antibiotic resistance pattern of streptococcus spp. isolated from clini ... | 2017 | 28601447 |
| bovine intra-mammary challenge with streptococcus dysgalactiae spp. dysgalactiae to explore the effect on the response of complement activity. | recently published work as described by the authors highlighted the extent of complement activity in bovine milk. localised mastitis infection occurring in the mammary glands of dairy cows is readily detectable by the levels of somatic cells in milk. thus, it is opportune to monitor complement activity in milks in association with the animal's innate immune response to mammary infection. preliminary screening of milk samples taken randomly showed that milk with a high somatic cell count (scc) re ... | 2017 | 28625182 |
| clonal clusters and virulence factors of group c and g streptococcus causing severe infections, manitoba, canada, 2012-2014. | the incidence of group c and g streptococcus (gcgs) bacteremia, which is associated with severe disease and death, is increasing. we characterized clinical features, outcomes, and genetic determinants of gcgs bacteremia for 89 patients in winnipeg, manitoba, canada, who had gcgs bacteremia during 2012-2014. of the 89 patients, 51% had bacteremia from skin and soft tissue, 70% had severe disease features, and 20% died. whole-genome sequencing analysis was performed on isolates derived from 89 blo ... | 2017 | 28628457 |