Publications

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the efficacy of povidone-iodine products against periodontopathic bacteria.a total of 8 strains of 6 bacterial species, porphyromonas gingivalis atcc33277 and tdc286, actinobacillus actinomycetemcomitans atcc29523 and jp2, fusobacterium nucleatum no. 2, tannerella forsythensis atcc43937, prevotella intermedia atcc25611 and streptococcus anginosus atcc33397, were treated with povidone-iodine (pvp-i) gargle (pvp-i: 0.47 and 0.23% w/v) or chlorhexidine gluconate (chg) gargle (chg: 0.002% w/v) for 15, 30 or 60 s, after which they were inoculated into various media, culture ...200616490986
deep neck infection complicating lymphadenitis caused by streptococcus intermedius in an immunocompetent child.streptococcus intermedius belongs to the streptococcus anginosus group. it is part of the normal flora of the human mouth, but it can be etiologically associated with deep-site infections.200616553945
in vitro activity of sitafloxacin compared with several fluoroquinolones against streptococcus anginosus and streptococcus constellatus.the in vitro activities of sitafloxacin and seven other fluoroquinolones a (ciprofloxacin, tosufloxacin, sparfloxacin, levofloxacin, t-3811me, moxifloxacin and trovafloxacin) were examined by the microdilution method against 79 clinically isolated 'streptococcus milleri' group (smg) microorganisms. no statistically significant differences were found between the minimum inhibitory concentrations (mic(50) and mic(90)) against streptococcus anginosus and streptococcus constellatus. sitafloxacin was ...200616417990
bactericidal effect of nd:yag laser irradiation on some endodontic pathogens ex vivo.to define the role of neodymium:yttrium-aluminum-garnet (nd:yag) lasers in root canal disinfection along with a minimally invasive treatment concept.200616776759
bacterial profile and burden of periodontal infection in subjects with a diagnosis of acute coronary syndrome.periodontitis has been identified as a potential risk factor in cardiovascular diseases. it is possible that the stimulation of host responses to oral infections may result in vascular damage and the inducement of blood clotting. the aim of this study was to assess the role of periodontal infection and bacterial burden as an explanatory variable to the activation of the inflammatory process leading to acute coronary syndrome (acs).200616805672
[cervical abscess by streptococcus anginosus-milleri after foreign body ingestion and suspicion of esophageal perforation].we report a case of cervical abscess after the ingestion of foreign body (chicken bone) secondary to probable esophageal perforation that it was sent to us with suspicion of mediastinal complication. the girl, 17 years-old, nothing else to arrive our hospitalary center required entrance in icu due to her severe clinical process: high fever, intense neck-thoracic pain, laterocervical diffuse and progressive left inflammation and bad general state. the ct showed the presence of a well defined absc ...200616881550
microbiological composition associated with interleukin-1 gene polymorphism in subjects undergoing supportive periodontal therapy.interleukin-1 gene polymorphism (il-1 gene) has been associated with periodontitis. the present study examined the subgingival microbiota by il-1 gene status in subjects undergoing supportive periodontal therapy (spt).200616881809
luxs-mediated signalling in streptococcus anginosus and its role in biofilm formation.the autoinducer-2 signal (ai-2) produced by several gram-positive and gram-negative bacteria mediates interspecies communication. in this study we were able to identify an orthologue of luxs, required for the synthesis of ai-2 signals, in streptococcus anginosus. comparative analyses revealed conserved sequences in the predicted s. anginosus luxs. expression of luxs was highest during early exponential growth phase. compared to other oral streptococci, conditioned media from growth of members of ...200616897563
use of the phoenix automated system for identification of streptococcus and enterococcus spp.the phoenix system (becton dickinson diagnostic systems, sparks, md) was evaluated for identification (id) to the species level of streptococci and enterococci. two hundred clinical isolates were investigated: beta-hemolytic streptococci (n = 50), streptococcus pneumoniae organisms (n = 46), viridans group streptococci (n = 31), enterococcus faecium (n = 36), enterococcus faecalis (n = 25), and other catalase-negative cocci (n = 12). the api system (biomérieux, marcy l'etoile, france) was used a ...200616954258
images in clinical medicine. elevated jugular venous pressure. 200616971712
coaggregation interactions between oral and endodontic enterococcus faecalis and bacterial species isolated from persistent apical periodontitis.interactions between enterococcus faecalis and other species found in root canal infections might be important for the development and persistence of periapical disease. the aim of this study was to investigate the coaggregation interactions between e. faecalis clinical isolates and species previously shown to survive and induce apical periodontitis in monkeys: peptostreptococcus anaerobius, prevotella oralis, fusobacterium nucleatum, and streptococcus anginosus. intergeneric coaggregation assay ...200616982270
human t-cell responses to oral streptococci in human pbmc-nod/scid mice.we investigated cellular and humoral immune responses to oral biofilm bacteria, including streptococcus mutans, streptococcus anginosus, streptococcus sobrinus, and streptococcus sanguinis, in nod/scid mice immunized with human peripheral blood mononuclear cells (hu-pbmc-nod/scid mice) to explore the pathogenicity of each of those organisms in dental and oral inflammatory diseases. hu-pbmc-nod/scid mice were immunized by intraperitoneal injections with the whole cells of the streptococci once a ...200616626374
rapid differentiation between members of the anginosus group and streptococcus dysgalactiae subsp. equisimilis within beta-hemolytic group c and g streptococci by pcr.based on a pair of primers developed initially for differentiating the anginosus group from other viridans streptococci, the pcr reported here can also differentiate between members of the anginosus group and streptococcus dysgalactiae subsp. equisimilis among beta-hemolytic group c and g streptococci. the resulting 742-bp pcr product was specific for members of the anginosus group, although a smaller, nonspecific product (361 bp) was generated from s. dysgalactiae subsp. equisimilis. restrictio ...200616672416
oral streptococcal strains isolated from odontogenic infections and their susceptibility to antibiotics.the aim of this study was to identify at species level and to investigate the antibiotic susceptibility of oral streptococcal strains isolated from 100 pus samples collected from romanian patients with different odontogenic infections. the isolates were identified at species level using the rapid id 32 strep system and their susceptibility was testing by the etest, against: penicillin g, ampicillin, erythromycin, clindamycin and tetracycline. for the investigation of erythromycin resistance phen ...200617438917
antimicrobial activity of mahonia aquifolium and two of its alkaloids against oral bacteria.extracts or alkaloids isolated from mahonia aquifolium exhibit antimicrobial activity against gram-positive and gram-negative bacteria, fungi, and protozoa. in this study the bacteriostatic and bacteriocidal activities of a m. aquifolium extract and two of its major alkaloids, berberine chloride and oxyacanthine sulphate, were tested in vitro against nine different oral bacteria. minimum inhibitory concentrations were in the range from < or = 0.0031% to 0.1993% for the m. aquifolium extract, fro ...200718072463
response to alkaline stress by root canal bacteria in biofilms.to determine whether bacteria isolated from infected root canals survive alkaline shifts better in biofilms than in planktonic cultures.200717326786
streptococcus milleri group infection associated with digestive fistula in patients with vascular graft: report of seven cases and review.we described seven patients with streptococcus milleri group aortic (six patients) or vena cava (one patient) graft infection secondary to a vasculo-digestive fistula. time between vascular graft setting and first clinical signs varied from eight months to more than thirteen years. six patients had fever. three patients presented with recurrent fever for more than nine months and in two of these cases, delay before diagnosis was long because repeated blood cultures were sterile. three patients h ...200717565461
synthetic bromated furanone inhibits autoinducer-2-mediated communication and biofilm formation in oral streptococci.autoinducer-2 (ai-2) is a widespread communication-signal molecule that allows bacteria to sense and react to environmental factors. in some streptococci ai-2 is reported to be involved in virulence expression and biofilm formation. it has earlier been shown that the alga delisea pulchra produces bromated furanones, which prevent bacterial colonization of the algae.200717803632
evaluation of the microbiota of primary endodontic infections using checkerboard dna-dna hybridization.the aim of this study was to evaluate the composition of the microbiota of primary endodontic infections in 111 selected cases of single-rooted teeth with necrotic pulp.200717949342
bacterial examination of endodontic infections by clonal analysis in concert with denaturing high-performance liquid chromatography.the aim of this study was to examine the diversity of bacterial species in the infected root canals of teeth associated with endodontic abscesses by cloning and sequencing techniques in concert with denaturing high-performance liquid chromatography.200717949344
[identifying group g beta-hemolytic streptococci strains by 16s rdna sequencing].to identify the dna sequences of 26 beta-hemolytic group g streptococci strains isolated from the swabs of patients in a glomerulonephritis outbreak event.200718095606
[phenotypes and genetic mechanisms of resistance to macrolides and lincosamides in viridans group streptococci].viridans group streptococci (vgs) are part of the oropharyngeal, intestinal and genital flora, but they may cause endocarditis and bacteremia in susceptible patients. penicillin- and macrolide-resistant strains are increasing every year. the aim of this study was to investigate genetic mechanisms of resistance to macrolides in clinically relevant isolates. we identified 85 isolates from january 2004 to june 2006. susceptibility to penicillin, cefotaxime, erythromycin, clindamycin and gentamycin ...200718080028
tigecycline (gar-936) activity against streptococcus gallolyticus (bovis) and viridans group streptococci.viridans group streptococci including streptococcus gallolyticus (formerly s. bovis) represent serious invasive pathogens often associated with endocarditis or sepsis among immunocompromised or cancer patients. tigecycline (gar-936), the first clinically studied glycylcycline, has a potent gram-positive activity with a potential treatment option for these streptococcal infections. the studied collection (848 strains) included 100 isolates each of streptococcus anginosus, streptococcus constellat ...200716989974
ai-2 quorum sensing affects antibiotic susceptibility in streptococcus anginosus.the concern over rising antibiotic resistance necessitates exploration of alternative approaches in antimicrobial therapy. bacterial communities use the auto-inducer 2 (ai-2) quorum sensing signal at a specific threshold level for intra- and interspecies communication in order to regulate virulence behaviour. ai-2 signal production occurs in bacteria that possess a luxs homologue. in this study, we investigate for the first time the association between ai-2 signalling and susceptibility to antib ...200717491000
intrathecal granuloma and intramedullary abscess associated with an intrathecal morphine pump.objective and importance. several previous reports have documented cord compression resulting from the formation of an intrathecal inflammatory mass in patients using intrathecal drug delivery systems. we present the first reported case of an intramedullary abscess and intrathecal inflammatory mass associated with an intrathecal drug delivery system. clinical presentation. a 47-year-old man was transferred to our institution from an outside hospital with a 3-week history of the inability to am ...200722151806
the in-vitro antimicrobial activity of abrus precatorius (l) fabaceae extract on some clinical pathogens.to investigate the in-vitro antimicrobial activities of the extracts of abrus precatorius on some clinical isolates as resistance to available and affordable antibiotics by these pathogens is on the increase.200818408781
[virulence factors of anginosus group streptococci]. 200819317232
strongyloides stercoralis infection associated with repititive bacterial meningitis and siadh: a case report.strongyloidiasis is an infection by the intestinal parasite strongyloides stercoralis, which usually stays asymptomatic. in some situations a hyperinfection or disseminated disease can occur. we report a case of a 49-year-old congolese man with a medical history of 5 episodes of bacterial meningitis, who presents himself with a paralytic ileus and a low serum sodium. a strongyloides hyperinfection with a syndrome of inappropriate secretion of the antidiuretic hormone (siadh) was diagnosed. after ...200819317285
culture-negative intracerebral abscesses in children and adolescents from streptococcus anginosus group infection: a case series.we report the use of 16s ribosomal rna gene amplification and sequencing to diagnose culture-negative intracerebral abscesses in younger patients. these 3 cases demonstrate the optimal application of gene sequencing from direct specimens for patients with negative culture results compromised by antibacterial therapy but histories highly suggestive of acute bacterial infection.200818419492
molecular and enzymatic characterization of betac-s lyase in streptococcus constellatus.streptococcus anginosus and streptococcus constellatus are frequently isolated from dental abscesses and other suppurative lesions. we previously reported that betac-s lyase from a strain of s. anginosus produced significantly more hydrogen sulfide than betac-s lyases from other streptococci. the purpose of this study was to establish the molecular and enzymatic features of the betac-s lyase in s. constellatus and to elucidate whether this unique capacity is common to many strains of s. constell ...200818402612
peritonitis due to streptococcus anginosus in patients treated with capd: a report of two cases. 200818474928
oral bacteria in biofilms exhibit slow reactivation from nutrient deprivation.the ability of oral bacteria to enter a non-growing state is believed to be an important mechanism for survival in the starved micro-environments of the oral cavity. in this study, we examined the reactivation of nutrient-deprived cells of two oral bacteria in biofilms, streptococcus anginosus and lactobacillus salivarius. non-growing cells were generated by incubation in 10 mm potassium phosphate buffer for 24 h and the results were compared to those of planktonic cultures. when both types of c ...200818599821
orbital cellulitis with abscess formation following surgical treatment of canaliculitis.the authors report a case of orbital cellulitis with abscess formation that developed after surgical management of canaliculitis. the patient developed pain, erythema, proptosis, and limited eye movements 3 days after canalicular debridement. she required urgent drainage of an orbital abscess and was treated with intravenous antibiotics for 2 weeks. complications from surgical management of canaliculitis are unusual. clinicians should be aware of the rare but serious risk of spread of the infect ...200818645442
neurological complication of infective endocarditis mimicking temporal arteritis. 200818230882
rapid and reliable identification of streptococcus anginosus group isolates to the species level by real-time pcr and melting curve analysis.a real-time pcr assay is described for rapid and accurate identification of the streptococcus anginosus group members. based on melting curve analysis, the s. anginosus species isolates could be further subdivided into two subgroups, each associated with different clinically relevant ribotypes of s. anginosus.200818652853
[streptococcus anginosus and streptococcus gallolyticus subsp. pasteurianus chorioamniotitis]. 200818667285
[multiple abscessing of valvular apparatus of the heart in a patient with secondary infectious endocarditis].progressive growth of infectious endocarditis morbidity has been noted in the world during recent 10 years. among secondary forms of endocarditis rate of congenital heart defects is 21%. according to data of m.k. rybakova (2007) the highest risk of development of infectious endocarditis (74%) is noted on bicuspid aortic valve. we present a clinical case of the patient c. with bicuspid aortic valve, secondary infectious endocarditis of aortic and mitral valves complicated with multiple abscessing ...200818789036
splenic abscess due to streptococcus anginosus. case report.splenic abscess is a rare condition. haematogenous seeding to the spleen from an infection at a distant site, most often endocarditis, is been the most common predisposing condition but an increase has been observed in immuno-compromised patients too. fever, leukocytosis and left upper quadrant pain are suggestive, but the signs and symptoms of splenic abscesses are often non-specific. rare is the onset with diarrhoea as in our case. ultrasound and computed tomography are reliable diagnostic too ...200818834569
effect of photo-activated disinfection on endodontic pathogens ex vivo.to test the hypothesis that photo-activated disinfection (pad) has a bactericidal effect on pathogens inoculated in root canals, with emphasis on biofilm formation/destruction.200818081808
microbiological evaluation of primary endodontic infections in teeth with and without sinus tract.to examine the microbiological status of primary endodontic infections in teeth with and without a sinus tract.200818422583
prevalence of bacteraemia following third molar surgery.to investigate the prevalence and aetiology of bacteraemia following third molar extractions (b-tme), analysing the factors affecting its development.200818173454
identification and molecular analysis of betac-s lyase producing hydrogen sulfide in streptococcus intermedius.hydrogen sulfide (h(2)s) is a toxic gas that induces the modification and release of haemoglobin in erythrocytes; however, it also functions in methionine biosynthesis in bacteria. betac-s lyase, encoded by the lcd gene, is responsible for bacterial h(2)s production through the cleavage of l-cysteine. in this study, 26 of 29 crude extracts from reference and clinical strains of streptococcus intermedius produced h(2)s from l-cysteine. the capacities in those strains were not higher than those in ...200818927421
streptococcus intermedius causing infective endocarditis and abscesses: a report of three cases and review of the literature.streptococcus intermedius is a member of the streptococcus anginosus group. clinical disease with s. intermedius is characterized by abscess formation and rarely endocarditis. identification of streptococcus intermedius is difficult, leading to the development of molecular methods to more accurately identify and characterize this organism.200818992173
aortic valvular endocarditis with mobile vegetations and intracoronary embolism: demonstration by cardiac multislice computed tomography. 200818267937
the lower genital tract microbiota in relation to cytokine-, slpi- and endotoxin levels: application of checkerboard dna-dna hybridization (cdh).in the present study the lower genital tract microbiota in asymptomatic fertile women (n=34) was identified and quantified by culturing vaginal secretions. also, vaginal and cervical samples were analyzed by a semiquantitative checkerboard dna-dna hybridization technique (cdh) based on genomic probes prepared from 13 bacterial species (bacteroides ureolyticus, escherichia coli, fusobacterium nucleatum, gardnerella vaginalis, mobiluncus curtisii ss curtisii, prevotella bivia, prevotella disiens, ...200818397461
does pregnancy have an impact on the subgingival microbiota?we investigated clinical and subgingival microbiologic changes during pregnancy in 20 consecutive pregnant women > or =18 years not receiving dental care.200919228092
molecular characterization of macrolide resistance determinants [erm(b) and mef(a)] in streptococcus pneumoniae and viridans group streptococci (vgs) isolated from adult patients with cystic fibrosis (cf).although long-term use of azithromycin has shown a significant clinical improvement for patients with cystic fibrosis (cf), its long-term effect on the susceptibility of commensal flora within cf airways has not yet been examined. we therefore suggest that long-term use of azithromycin increases macrolide resistance in commensal streptococci.200919584106
ai-2/luxs is involved in increased biofilm formation by streptococcus intermedius in the presence of antibiotics.bacteria utilize quorum-sensing communication to organize their behavior by monitoring the concentration of bacterial signals, referred to as autoinducers (ais). the widespread detection of ai-2 signals and its enzymatic synthase (luxs) in bacteria suggests that ai-2 is an inter- and intraspecies communication signal. we have previously shown that antibiotic susceptibility is affected by ai-2 signaling in streptococcus anginosus. since chronic infections involve persistent biofilms resilient to ...200919596873
co-infection by streptococcus anginosus and mycobacterium tuberculosis: three case reports.abstract:200919178736
pneumorachis caused by metastatic gas gangrene.pneumorachis has previously been described only after spread from a contiguous site or after a traumatic event. our patient experienced sepsis due to multiple enteric organisms, and gas was identified within the spinal canal on computed tomographic imaging. we present the 1st case of pneumorachis caused by disseminated infection.200919004591
the microbiology of the acute dental abscess.the acute dental abscess is frequently underestimated in terms of its morbidity and mortality. the risk of potential serious consequences arising from the spread of a dental abscess is still relevant today with many hospital admissions for dental sepsis. the acute dental abscess is usually polymicrobial comprising facultative anaerobes, such as viridans group streptococci and the streptococcus anginosus group, with predominantly strict anaerobes, such as anaerobic cocci, prevotella and fusobacte ...200919141730
prevalence of erythromycin and clindamycin resistance among clinical isolates of the streptococcus anginosus group in germany.members of the streptococcus anginosus group (sag) are frequently involved in pyogenic infections in humans. in the present study, the antimicrobial susceptibility of 141 clinical sag isolates to six antimicrobial agents was analysed by agar dilution. all isolates were susceptible to penicillin, cefotaxime and vancomycin. however, 12.8 % displayed increased mic values (0.12 mg l(-1)) for penicillin. resistance to erythromycin was detected in eight (5.7 %) isolates. characterization of the erythr ...200919141740
population-based study of invasive disease due to beta-hemolytic streptococci of groups other than a and b.beta-hemolytic streptococci of groups other than a and b (nabs) are increasingly recognized as causes of clinically significant disease, but precise information about this heterogeneous group is lacking. we report the incidence of nabs infection and describe the epidemiologic and clinical characteristics.200919187026
evaluation of genotypic and phenotypic methods for differentiation of the members of the anginosus group streptococci.the terminology and classification of the anginosus group streptococci has been inconsistent. we tested the utility of 16s rrna gene and tuf gene sequencing and conventional biochemical tests for the reliable differentiation of the anginosus group streptococci. biochemical testing included rapid id 32 strep, api strep, fluo-card milleri, wee-tabs, and lancefield antigen typing. altogether, 61 anginosus group isolates from skin and soft tissue infections and four reference strains were included. ...200919495818
cerebral hemorrhage, splenic and renal embolisms due to infective endocarditis.infective endocarditis is occurring more and more frequently in elderly persons and it has been associated with various clinical, bacteriological, and prognostic features. we present a 63-year-old woman with infective endocarditis which is the first reported case with cerebral hemorrhage, splenic and renal embolisms.200919602795
hydrogen sulfide production from cysteine and homocysteine by periodontal and oral bacteria.hydrogen sulfide is one of the predominant volatile sulfur compounds (vscs) produced by oral bacteria. this study developed and evaluated a system for detecting hydrogen sulfide production by oral bacteria.200919905954
[dyspnea with fever]. 200919953051
crystallization and preliminary x-ray analysis of betac-s lyases from two oral streptococci.hydrogen sulfide, which causes oral malodour, is generally produced from l-cysteine by the action of betac-s lyase from oral bacteria. the betac-s lyases from two oral bacteria, streptococcus anginosus and s. gordonii, have been cloned, overproduced, purified and crystallized. x-ray diffraction data were collected from the two types of crystals using synchrotron radiation. the crystal of s. anginosus betac-s lyase belonged to the orthorhombic space group p2(1)2(1)2(1), with unit-cell parameters ...200919724121
gene cloning and characterization of streptococcus intermedius fimbriae involved in saliva-mediated aggregation.streptococcus intermedius, an oral commensal and a cause of systemic pyogenic disease, expresses fimbriae. to identify the gene(s) encoding these fimbriae, we used a serum raised against purified fimbriae to screen libaries of recombinant lambda phages. the cloned gene cluster encoding s. intermedius fimbriae, (saliva-mediated aggregation and adherence-associated fimbriae), contained 4 orfs, i.e. a putative ribonulease (saf1), a putative adhesin (saf2), the main pilus subunit (saf3) and a sortas ...200919819330
contribution towards developing a new semi-selective medium for streptococcus anginosus group.the aim of this study was to develop a new selective medium for isolation of streptococcus anginosus group (sag) strains, by adding sulphamethazine and aztreonam as selective agents at mitis-salivarius agar (msa), the medium commonly used for recovery of oral streptococci from oral samples. material and method: the evaluation of mitis-salivarius--sulphamethazine--aztreonam agar (mssaa) for sag selectivity was performed by testing the growth of type strains and laboratory-stored clinical isolates ...200920191907
[gram-positive cocci isolated from urocultures of ambulatory and hospitalized patients with surgical risk].we propose a comparative study of sensitivity to antibiotics of gram-positive germs isolated in urocultures from patients in ambulatory and two wards with surgical risk (urology and obstetrics-gynaecology), and also to establish the resistance phenotypes of these strains.200920524392
microflora of the penile skin-lined neovagina of transsexual women.the microflora of the penile skin-lined neovagina in male-to-female transsexuals is a recently created microbial niche which thus far has been characterized only to a very limited extent. yet the knowledge of this microflora can be considered as essential to the follow-up of transsexual women. the primary objective of this study was to map the neo-vaginal microflora in a group of 50 transsexual women for whom a neovagina was constructed by means of the inverted penile skin flap technique. second ...200919457233
characterization of the complex bacterial communities colonizing biliary stents reveals a host-dependent diversity.this study provides a comprehensive survey of the spatial and temporal bacterial composition of biliary stent biofilms. the bacterial diversity, distribution and dynamics of 59 biliary and 4 pancreatic stent communities from 40 patients being treated at two different hospitals, which implant stents either simultaneously or consecutively, were characterized by single-strand conformation polymorphism (sscp) analysis. fifty-one phylotypes belonging to 5 bacterial phyla and 24 bacterial families wer ...200919360025
the clinical importance of microbiological findings in the diagnosis and management of bloodstream infections.bloodstream infections are associated with high morbidity and mortality. accurate identification of blood isolates to the species level and identification of the source of infection and/or the portal of entry are crucial for optimal management of these infections. these investigations-in addition to clinical findings and laboratory and imaging studies-are central to informing and directing efficient and effective diagnostic examinations and to choosing the optimal antimicrobial regimen. four cas ...200919374579
streptococcus constellatus bacteremia causing septic shock following tooth extraction: a case report.organisms of the streptococcus milleri group consists of streptococcus intermedius, streptococcus constellatus, and streptococcus anginosus. though they are commonly associated with abscesses, bacteremia with subsequent septic shock and mortality is infrequent.200919829816
cervical necrotizing fasciitis. 200919344600
[hereditary hemorragic telangiectasia and hepatic abcess].we report the case of a 27-year-old man presenting with a hepatic abscess and hereditary hemorrhagic telangiectasia (hht). the association between hht and an infectious disease seemed to be induced by arteriovenous malformations and maybe also by a deficit of polymorphonuclear cells, a monocyte oxidative burst and phagocytosis. this diagnosis should be suggested in case of serious infections in young patients. prevention is based on screening for and destroying infection, antibioprophylaxis and ...201019403253
case records of the massachusetts general hospital. case 10-2010. a 37-year-old woman with weakness and a mass in the brain. 201020375410
contribution of streptococcus anginosus to infections caused by groups c and g streptococci, southern india.vellore, a region in southern india, has a high incidence of severe human infections with beta-hemolytic group c and g streptococci (gcgs). to determine the causative species in these infections, we conducted 16s rrna gene sequencing: streptococcus dysgalactiae subsp. equisimilis (81%) and s. anginosus (19%) were the causative organisms in the 2-year study period (2006-2007). we used pcr to detect the virulence-related emm gene; results showed that it was restricted to s. dysgalactieae subsp. eq ...201020350380
streptococcus anginosus (streptococcus milleri group) pyomyositis in a 50-year-old man with acquired immunodeficiency syndrome: case report and review of literature.we describe the first reported case of bacterial pyomyositis of the right thigh caused by streptococcus anginosus (s. milleri group) in an hiv-infected patient. the clinical presentation was complicated by multiple ring-enhancing lesions detected on magnetic resonance imaging of the brain. evaluation for central nervous system toxoplasmosis,syphilis, and cryptococcal infection was negative. aggressive antibiotic therapy directed against s. anginosus and surgical debridement were limb salvaging. ...201019904493
the effects of antimicrobials on endodontic biofilm bacteria.in the present study, confocal microscopy, a miniflow cell system, and image analysis were combined to test in situ the effect of antimicrobials and alkali on biofilms of enterococcus faecalis, lactobacillus paracasei, streptococcus anginosus, and streptococcus gordonii isolated from root canals with persistent infections.201020003938
descending deep neck infection in a liver transplant patient.descending deep neck space infections are serious conditions that appear as a complication of cervical and odontogenic infections. infecting bacteria descend into the mediastinum causing systemic toxicity and septic shock. liver transplant patients are at increased risk of developing life-threatening infections, but reports about descending deep neck space infections in these patients are scarce. here, we report a case of deep neck infection resulting in mediastinitis in a liver transplant patie ...201020051062
[mesenteric mycotic aneurysm: a rare complication of a bacterial endocarditis]. 201020092814
development of real-time pcr assays for detection of the streptococcus milleri group from cystic fibrosis clinical specimens by targeting the cpn60 and 16s rrna genes.cystic fibrosis (cf) is a multiorgan disease, with the majority of mortalities resulting from pulmonary failure due to repeated pulmonary exacerbations. recently, members of the streptococcus anginosus group (s. anginosus, s. constellatus, and s. intermedius), herein referred to as the "streptococcus milleri group" (smg) have been implicated as important etiological pathogens contributing to pulmonary exacerbations in cf patients. this is partly due to better microbiological detection of the smg ...201020164275
two cases of aneurysm of the anterior mitral valve leaflet associated with transcatheter aortic valve endocarditis: a mere coincidence? 201020167335
invasion of human aortic endothelial cells by oral viridans group streptococci and induction of inflammatory cytokine production.oral viridans group streptococci are the major commensal bacteria of the supragingival oral biofilm and have been detected in human atheromatous plaque. atherosclerosis involves an ongoing inflammatory response, reportedly involving chronic infection caused by multiple pathogens. the aim of this study was to examine the invasion of human aortic endothelial cells (haecs) by oral viridans group streptococci and the subsequent cytokine production by viable invaded haecs. the invasion of haecs by ba ...201021214874
hematogenous osteomyelitis caused by streptococcus anginosus group in a previously healthy child. 201020958867
the role of bacteria in oral cancer.despite the widening interest in the possible association between bacteria and different stages of cancer development, our knowledge in its relation to oral cancers remains inadequate. the aim of this review article is to derive a better understanding on the role of various micro-organisms in the etiogenesis of oral cancers through all the available data on the pubmed. different bacteria have been proposed to induce carcinogenesis either through induction of chronic inflammation or by interferen ...201021584217
pyogenic liver abscess secondary to streptococcus anginosus in an adolescent.pyogenic liver abscess in the pediatric population is a rare entity and can be difficult to manage. surgical infections caused by streptococcus anginosus are exceedingly rare. here we present a case of pyogenic liver abscess caused by s anginosus in an adolescent presenting with fever, nausea, emesis, and right upper quadrant abdominal discomfort.201020438908
mechanical non-surgical treatment of peri-implantitis: a single-blinded randomized longitudinal clinical study. ii. microbiological results.peri-implantitis is common in patients with dental implants. we performed a single-blinded longitudinal randomized study to assess the effects of mechanical debridement on the peri-implant microbiota in peri-implantitis lesions.201020507380
multiple liver abscesses with isolation of streptococcus intermedius related to a pyogenic dental infection in an immuno-competent patient.introduction: streptococcus intermedius - a member of the streptococcus anginosus group - is part of the normal microbial flora of the oral cavity. despite being regarded as a harmless apathogenic commensal, streptococcus intermedius has been described to cause abscesses in various locations of the body. - case presentation: we report the clinical case and course of treatment of a 18-year-old male patient presenting with multiple hepatic abscesses associated with an untreated pyogenic dental inf ...201020696645
cardiac computed tomography in endocarditis. 201020736211
it's not easy being green: the viridans group streptococci, with a focus on pediatric clinical manifestations.the viridans group streptococci (vgs) are a heterogeneous group of organisms that can be human commensals, colonizing the gastrointestinal and genitourinary tracts in addition to the oral mucosa. vgs are generally considered to be of low pathogenic potential in immunocompetent individuals. however, in certain patient populations, vgs can cause invasive disease, such as endocarditis, intra-abdominal infection, and shock. within the vgs, the rates and patterns of antimicrobial resistance vary grea ...201020810781
how many lives does an ulcerative colitis patient have? 201020833304
amplification of minute amounts of oral bacterial dna for real-time quantitative pcr analysis.high-throughput technologies for typing caries or health-associated bacterial populations including pcr, dna microarrays and next-generation sequencing techniques require significant amounts of bacterial dna. in clinical settings, the amount of sampled dna is often limited and amplification is therefore essential. protocols should be able to reproducibly amplify sequences in order to maintain initial sequence ratios and should not bias the representation of particular dna sequence types.201020881394
two cases of endogenous endophthalmitis caused by gram-positive bacteria with good visual outcome.background: endogenous endophthalmitis is a rare disease and its visual prognosis is poor. case reports: we present two patients, a 60-year-old man and a 53-year-old man, who developed endogenous endophthalmitis caused by gram-positive organisms but recovered good vision after antibiotics and vitrectomy. results: the first patient complained of ocular pain and visual decrease in his right eye. ophthalmoscopy showed inflammation in the anterior chamber and vitreous opacities. antibiotic was admin ...201021103197
gastrointestinal stromal tumor in a patient with neurofibromatosis: abscess formation in the tumor leading to bacteremia and seizure.a 66-year-old woman with neurofibromatosis type 1 (nf1) was brought to the emergency room with seizures and high-grade fever. seizure in adult nf1 patients raises concern for intracranial lesions. however, neurological examination and central nervous system imaging failed to detect any causative intracranial lesions for her seizure. gram-positive cocci, streptococcus anginosus, were detected by blood cultures. abdominal computed tomography revealed a well-defined round mass 7 cm in diameter, whi ...201021103203
identification of oral bacteria by 16s rrna gene analysis in elderly persons requiring nursing care.after incubation of saliva from 58 semi-bedridden elderly persons, the cultures were identified based on the 16s rrna gene base sequence to compare the identification by the conventional culture method. as a result, the 16s rrna gene base sequence of 198 strains identified by the culture method showed 98.5% or more homology in some of the human oral microbiome database, and the identification of bacterial species and genus was possible. when an organism identified by the 16s rrna gene sequencing ...201021110215
molecular characterization and phylogenetic analysis of quinolone resistance-determining regions (qrdrs) of gyra, gyrb, parc and pare gene loci in viridans group streptococci isolated from adult patients with cystic fibrosis.ciprofloxacin is the most frequently used member of the fluoroquinolones during initial eradication therapy of pseudomonas aeruginosa, as well as during acute pulmonary exacerbations. however, its long-term effect on the susceptibility of the commensal flora within the cystic fibrosis (cf) airways has not yet been examined. the aim of this study was therefore to examine the consequence of oral ciprofloxacin usage on the resistance of the commensal viridans group streptococci (vgs), in terms of m ...201021193474
mckay agar enables routine quantification of the 'streptococcus milleri' group in cystic fibrosis patients.the 'streptococcus milleri' group (smg) has recently been recognized as a contributor to bronchopulmonary disease in cystic fibrosis (cf). routine detection and quantification is limited by current cf microbiology protocols. mckay agar was developed previously for the semi-selective isolation of this group. here, mckay agar was validated against a panel of clinical smg isolates, which revealed improved smg recovery compared with columbia blood agar. the effectiveness of this medium was evaluated ...201020093379
[a young man with mononucleosis and swelling of the right eye].treatment of acute infections in the upper airways comprises a significant part of direct healthcare expenditure and is a challenge for healthcare professionals. in norway, 11,495 hospitalized days were recorded for acute infections (influenza and pneumonia excluded) in the upper airways in 2008. acute bacterial rhinosinusitis (abrs) is defined as inflammation of the nose and the paranasal sinuses characterized by both 1): symptoms of nasal blockage/obstruction/congestion or nasal discharge, and ...201121233887
multisite infective endocarditis with mural vegetations in the right atrium and right ventricle. 201121282522
microbiology and antibiotic management of orbital cellulitis.orbital infections caused by methicillin-resistant staphylococcus aureus may be increasing. because staphylococcus aureus infections have important treatment implications, our objective was to review the microbiology and antibiotic management of children hospitalized with orbital cellulitis and abscesses.201121321025
persistent epigastric pain in an 80-year-old man. 201121398231
unusual mammary abscess. 201121444940
breakthrough bacteremia and septic shock due to streptococcus anginosus resistant to daptomycin in a patient receiving daptomycin therapy.daptomycin is active against many gram-positive pathogens including multi-drug resistant organisms (3).…201121502623
experimental alveolitis in rats: microbiological, acute phase response and histometric characterization of delayed alveolar healing.the pathogenesis of alveolitis is not well known and therefore experimental situations that mimic some features of this disease should be developed.201121625744
concurrent postpartum uterine and abdominal wall dehiscence and streptococcus anginosus infection.: postpartum uterine scar dehiscence is a rare but potentially lethal complication of cesarean deliveries.201121768850
splenic abscess and multiple brain abscesses caused by streptococcus intermedius in a young healthy man.we report a case of splenic abscess with multiple brain abscesses caused by streptococcus intermedius in a healthy young man without any identifiable risk factors, which resolved with percutaneous drainage and antibiotics. streptococcus intermedius, a member of the streptococcus anginosus group, is a common commensal organism of the oral cavity and gastrointestinal tract, and it is a known cause of deep-seated infections. suppurative infections caused by streptococcus anginosus group are sometim ...201121738290
uv-c-irradiation sublethal stress does not alter antibiotic susceptibility of the viridans group streptococci to β-lactam, macrolide, and fluoroquinolone antibiotic agents.previous work has indicated that environmental stresses on bacteria might lead to an upregulation of stress response. led curing lights (315-400 nm) and other uv lights used in tooth whitening cosmetic procedures might act as stresses. we examined the effect of uv-c light, as a high-energy surrogate to the lower-energy uv-a light used in such instruments, to examine its effect on the antibiotic susceptibility of viridans group streptococci.201122887906
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