Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| diversity and stability of the staphylococcus intermedius flora in three bitches and their puppies. | the study investigated the transfer and the stability of the s. intermedius flora in three bitches and their puppies. a total of 240 cutaneous and mucosal isolates of s. intermedius was collected from three healthy cavalier king charles spaniels and their puppies during the immediate prepartum period and after whelping, over a total of 15 weeks. the isolates were genotyped with random amplified polymeric dna-polymerase chain reaction analysis (rapd-pcr) using two primers. seventeen different gen ... | 2003 | 14596535 |
| isolation of exfoliative toxin from staphylococcus intermedius and its local toxicity in dogs. | a rounding effect was demonstrated in cultured cells inoculated with the culture filtrates (cfs) of 60 strains of staphylococcus intermedius derived from dogs affected with pyoderma. exfoliative toxin (et)-like toxin (etlt) was isolated from the cf of s. intermedius strain d-52, which exhibited strong rounding activity and then was purified by gel filtration on a sephadex g-75 column, and by sodium dodecyl sulfate polyacrylamide gel electrophoresis (sds-page). the etlt caused exfoliation in 1-da ... | 2003 | 12742712 |
| cloning of the gene coding for staphylococcus intermedius exfoliative toxin and its expression in escherichia coli. | an exfoliative toxin (siet)-producing strain (d-52) of staphylococcus intermedius derived from canine pyoderma did not possess large plasmids. therefore, the gene coding for siet was considered to be located on the chromosomal dna. the siet gene was cloned from the chromosomal dna of s. intermedius and was expressed in escherichia coli. the nucleotide sequence of the siet gene consists of a coding region of 990 bp specifying a polypeptide of 330 amino acid residues, which included a putative 42- ... | 2003 | 12742713 |
| antibiotic resistance in animals. | there is currently no systematic surveillance or monitoring of antibiotic resistance in australian animals. registration of antibiotics for use in animals is tightly controlled and has been very conservative. fluoroquinolones have not been registered for use in food producing animals and other products have been removed from the market because of human health concerns. in the late 1970s, the animal health committee coordinated a survey of resistance in salmonella and escherichia coli isolates fr ... | 2003 | 12807287 |
| interaction between probiotic lactic acid bacteria and canine enteric pathogens: a risk factor for intestinal enterococcus faecium colonization? | selected probiotic lactic acid bacteria (lab) have been shown to elicit positive health effects particularly in humans. competitive exclusion of pathogens is one of the most important beneficial health claims of probiotic bacteria. the effect of probiotic lab on competitive exclusion of pathogens has been demonstrated in humans, chicken and pigs. in this study we evaluated the ability of certain lab strains (lactobacillus rhamnosus gg, bifidobacterium lactis bb12, lactobacillus pentosus uk1a, l. ... | 2003 | 12488075 |
| detection of secreted peptides by using hypothesis-driven multistage mass spectrometry. | a method is presented for the rapid detection and characterization of trace amounts of peptides secreted from microorganisms, including pheromones, virulence factors, and quorum-sensing peptides. the procedure, based on targeted multistage ms, uses a novel matrix-assisted laser desorptionionization-ion trap mass spectrometer to overcome limitations of current ms methods (limited dynamic range, signal suppression effects, and chemical noise) that impair observation of low abundance peptides from ... | 2003 | 12591958 |
| assessment of the aerobic faecal microflora in mink (mustela vison schreiber) with emphasis on escherichia coli and staphylococcus intermedius. | the present study was undertaken to investigate the culturable aerobic faecal microflora of mink from newborn until adulthood with emphasis on the potential pathogens escherichia coli and beta-haemolytic coagulase positive staphylococci. rectal swabs were taken from 10 healthy dams and their offspring on seven mink farms throughout the production season and a semi-quantitative enumeration of total e. coli and haemolytic e. coli, beta-haemolytic streptococci, beta-haemolytic coagulase positive st ... | 2003 | 12695047 |
| hematogenous septic arthritis in the dog: results of five patients treated nonsurgically with antibiotics. | this retrospective study evaluates the effectiveness of nonsurgical treatment using antibiotics to treat hematogenous septic arthritis in five dogs. giant-breed dogs were over-represented, with all dogs <1 year of age. synovial fluid cultures were positive in all cases, with common bacterial species isolated that included streptococcus b-haemolytic spp., pasteurella multocida, and staphylococcus intermedius. dogs treated with appropriate duration and selection of antibiotics had clinical resolut ... | 2003 | 14736723 |
| transmission of multiple antimicrobial-resistant staphylococcus intermedius between dogs affected by deep pyoderma and their owners. | the occurrence of antimicrobial-resistant staphylococcus intermedius strains was investigated in 13 dogs affected by deep pyoderma, their owners and 13 individuals without daily contact with dogs (control group). a total of 90 canine and 33 human s. intermedius isolates were typed by pulsed field gel electrophoresis (pfge) to determine their possible identity. the occurrence of s. intermedius in dog-owners was significantly higher compared with the control group (fisher's exact test, p=0.03), wi ... | 2004 | 14738778 |
| molecular confirmation of transmission route of staphylococcus intermedius in mastoid cavity infection from dog saliva. | we report a case of infection of a mastoid cavity after mastoidectomy had been performed for chronic otitis media with cholesteatoma. the infection was caused by staphylococcus intermedius after a pet dog had licked the patient's ears. bacterial strains from the dog's saliva and the otorrhea in the patient were confirmed to be identical by pulsed-field gel electrophoresis analysis. the possibility of an oral transmission route of s. intermedius from pets to humans should be noted. | 2004 | 14991518 |
| treatment of canine pyoderma with ibafloxacin and marbofloxacin--fluoroquinolones with different pharmacokinetic profiles. | dogs with superficial or deep pyoderma (n = 228) presented to first opinion veterinarians (n = 20) were treated orally with either ibafloxacin, at a dosage of 15 mg/kg, or marbofloxacin, at a dosage of 2 mg/kg, once daily for 3-16 weeks. on initial presentation, 35% of the cases were classified as having recurrent pyoderma and 40% as having deep pyoderma. staphylococci (mainly staphylococcus intermedius) were isolated from over 90% of the cases. the average treatment periods were 41 +/- 26 and 3 ... | 2004 | 15189300 |
| in vitro antimicrobial activity of orbifloxacin against staphylococcus intermedius isolates from canine skin and ear infections. | the objective of the study was to evaluate the in vitro activity of orbifloxacin against staphylococcus intermedius strains isolated in france from canine skin and ear infections. the minimum inhibitory concentrations (mics) of orbifloxacin against 240 field s. intermedius isolates (69 skin and 171 ear isolates) ranged from 0.016 to 8 mg l(-1), with mic50 and mic90 equal to 0.5 and 1 mg l(-1), respectively. only one strain, a pyoderma isolate was resistant (mic=8 mg l(-1)). orbifloxacin was test ... | 2004 | 15120955 |
| identification and prevalence of an enterotoxin-related gene, se-int, in staphylococcus intermedius isolates from dogs and pigeons. | to determine the prevalence of enterotoxin-producing staphylococcus intermedius in dogs and pigeons. | 2004 | 15139930 |
| prevalence and characterization of leukotoxin-producing staphylococcus intermedius in isolates from dogs and pigeons. | staphylococcus intermedius isolates from dogs (n = 44) and pigeons (n = 62) were categorized into 12 types by intergenic ribosomal dna spacer polymorphism analysis. all isolates from pigeons were luks positive and all isolates from dogs were luks and lukf positive by dot blot analysis. the mean leukotoxicity titer for dog isolates was at least 129-fold higher than that for pigeon isolates. | 2004 | 15528733 |
| a seven-year survey of susceptibility to marbofloxacin of pathogenic strains isolated from pets. | this study, vetoquinol s.a. epidemiosurveillance, was conducted from 1994 to 2001 in order to determine the susceptibility (by mic determination) to marbofloxacin (a third generation fluoroquinolone used only in individual administration for animals). strains from infected pets originated from six european countries. isolates were collected from urinary infections (escherichia coli), respiratory infections (pasteurella multocida), dermatological infections (staphylococcus intermedius, pseudomona ... | 2004 | 15555883 |
| clinical isolates of staphylococcus intermedius masquerading as methicillin-resistant staphylococcus aureus. | staphylococcus intermedius is a zoonotic organism that can be associated with human disease. we report two separate cases of s. intermedius infection in which a false-positive rapid penicillin binding protein 2a latex test in conjunction with the phenotypic properties of beta-hemolysis and coagulase positivity allowed the clinical isolates to masquerade as methicillin-resistant staphylococcus aureus. 16s rrna gene sequencing and the absence of meca revealed the strains to be methicillin-suscepti ... | 2004 | 15583331 |
| a prospective study of the clinical findings, treatment and histopathology of 44 cases of pyotraumatic dermatitis. | pyotraumatic dermatitis (hot spot) is a common clinical syndrome in dogs but there are few prospective scientific studies related to it. the aim of this study was to investigate correlations among clinical pyotraumatic dermatitis, histopathology of the lesions and possible predisposing causes. the relationship of these with breed, age, sex and location of lesion was assessed statistically. a clinical diagnosis of acute pyotraumatic dermatitis was made in 44 privately owned dogs. males exceeded f ... | 2004 | 15585012 |
| iliopsoas abscess with iliac and femoral vein thrombosis in an adult siberian husky. | a nine-year-old, male siberian husky was presented with fever, decreased appetite and activity, non-weightbearing lameness, and oedematous swelling of the right inguinal and preputial area and the right hindlimb. an abscess within the right iliopsoas muscle, with severe thrombosis of the iliac and femoral vein, was diagnosed by haematology and diagnostic imaging. the abscess and adjoining lymph node were removed surgically through a median coellotomy. the isolated pathogen was staphylococcus int ... | 2004 | 14984156 |
| pet animals as reservoirs of antimicrobial-resistant bacteria. | pet animal numbers have substantially increased in modern society and attention is increasingly devoted to pet welfare. because of these changes, antimicrobial agents are frequently used in small animal veterinary practice, often including antimicrobial preparations used in human medicine, with heavy use of broad-spectrum agents such as aminopenicillins plus clavulanic acid, cephalosporins and fluoroquinolones. several longitudinal studies conducted at veterinary hospitals have indicated that re ... | 2004 | 15254022 |
| methicillin resistance of staphylococci isolated from the skin of dogs with pyoderma. | to determine the methicillin-resistant profile of staphylococcal isolates from the skin of dogs with pyoderma. | 2004 | 15478775 |
| development of a pcr test to differentiate between staphylococcus aureus and staphylococcus intermedius. | the presence of staphylococcus intermedius in food remains unclear because routine laboratory analysis does not discriminate between s. intermedius and staphylococcus aureus, a major cause of food poisoning. both species share many phenotypic characteristics, including coagulase and thermonuclease production. in both species, some strains can produce enterotoxin and therefore can be the cause of food poisoning outbreaks. although the id32 staph system (biomérieux, sa, marcy l'etoile, france), ba ... | 2004 | 15508648 |
| a prospective comparison between stabilized glutaraldehyde and chlorhexidine gluconate for preoperative skin antisepsis in dogs. | to compare the efficacy of 0.3% stabilized glutaraldehyde and alcohol (sg+a), 0.3% sg and water (sg+w), and 4% chlorhexidine gluconate tincture (cg+a), as skin disinfectants in dogs undergoing ovariohysterectomy. | 2004 | 15659020 |
| development and evaluation of a quality-controlled ribosomal sequence database for 16s ribosomal dna-based identification of staphylococcus species. | to establish an improved ribosomal gene sequence database as part of the ribosomal differentiation of microorganisms (ridom) project and to overcome the drawbacks of phenotypic identification systems and publicly accessible sequence databases, both strands of the 5' end of the 16s ribosomal dna (rdna) of 81 type and reference strains comprising all validly described staphylococcal (sub)species were sequenced. assuming a normal distribution for pairwise distances of all unique staphylococcal sequ ... | 2004 | 15528685 |
| species specificity in the adherence of staphylococci to canine and human corneocytes: a preliminary study. | staphylococcal pyoderma is rarely contagious between dogs and humans, or humans and dogs. this study investigated the hypothesis that there are species differences in adherence of staphylococcus intermedius (the most common isolate from dogs) and staphylococcus aureus (the most common isolate from humans) to canine and human corneocytes. sheets of corneocytes were collected from the ventral abdomen of 10 dogs and the medial forearm of 10 humans (all healthy and without any history or physical si ... | 2005 | 15960628 |
| comparative mutant prevention concentrations of pradofloxacin and other veterinary fluoroquinolones indicate differing potentials in preventing selection of resistance. | pradofloxacin (pra) is an 8-cyano-fluoroquinolone (fq) being developed to treat bacterial infections in dogs and cats. its mutant prevention concentrations (mpc) were determined for escherichia coli atcc 8739 at 0.225 microg/ml, and for staphylococcus aureus atcc 6538 at 0.55 microg/ml. at drug concentrations equal to or above the mpc, growth (implying selective clonal expansion) of first-step fq-resistant variants, naturally present in large bacterial populations, was inhibited. mpc(90) derived ... | 2005 | 16189094 |
| adherence of staphylococcus intermedius to corneocytes of healthy and atopic dogs: effect of pyoderma, pruritus score, treatment and gender. | staphylococcal pyoderma occurs commonly in atopic dogs. some studies have suggested that adherence of staphylococci to corneocytes of atopic dogs and humans is higher than to corneocytes of healthy individuals. this hypothesis and possible differences resulting from the presence or absence of pyoderma, the severity of pruritus or the effect of treatment or gender, were studied. adherent bacteria (staphylococcus intermedius) were quantified by computerized image analysis on corneocytes collected ... | 2005 | 16359305 |
| microbiological quality of goat's milk obtained under different production systems. | in order to determine the safety of milk produced by smallholder dairy goat farms, a farm-based research study was conducted on commercial dairy goat farms to compare the microbiological quality of milk produced using 3 different types of dairy goat production systems (intensive, semi-intensive and extensive). a survey of dairy goat farms in and around pretoria carried out by means of a questionnaire revealed that most of the smallholder dairy goat farms surveyed used an extensive type of produc ... | 2005 | 16108524 |
| characteristics of staphylococcus intermedius isolates from diseased and healthy dogs. | staphylococcus intermedius isolates from diseased and healthy dogs were examined for production of extracellular enzymes and toxins, and phage patterns. there were no significant differences between the two groups of isolates in the production rates of dnase, protease, lipase, gelatinase, hyaluronidase, hemolysins, protein a, and tsst-1, or in phage patterns. but the production rate of enterotoxins in isolates from diseased dogs was significantly higher than that in isolates from healthy dogs. p ... | 2005 | 15699604 |
| staphylococcus pseudintermedius sp. nov., a coagulase-positive species from animals. | four staphylococcal isolates from clinical and necropsy specimens from a cat, a dog, a horse and a parrot (psittacus erithacus timneh) were found to constitute a distinct taxon. 16s rrna gene sequence analysis revealed that its closest phylogenetic relatives are staphylococcus intermedius and staphylococcus delphini. growth characteristics, biochemical features and dna-dna hybridizations demonstrated that the strains differ from these and other known species and that they represent a single, nov ... | 2005 | 16014483 |
| antimicrobial drug susceptibility of staphylococcus intermedius clinical isolates from canine pyoderma. | a total of 50 staphylococcus intermedius strains isolated in france from canine pyodermas in 2002 were investigated for their susceptibility to various antimicrobial drugs. antimicrobial susceptibility was assessed using a 2-fold serial dilution method in mueller-hinton agar, and the minimal inhibitory concentrations (mics) were determined. about 62% of the 50 strains tested were producers of beta-lactamase and categorized as penicillin-resistant. about 26% demonstrated resistance to sulphonamid ... | 2005 | 15702997 |
| topical fusidic acid/betamethasone-containing gel compared to systemic therapy in the treatment of canine acute moist dermatitis. | the efficacy of a topical preparation containing 0.5% fusidic acid and 0.1% betamethasone-17-valerate was compared to a systemic therapy (comprising a combination of parenteral dexamethasone and oral clavulanate-potentiated amoxycillin) in the treatment of 104 dogs with acute moist dermatitis. significant improvement was evident after seven days in both treatment groups in all clinical parameters assessed and there was no significant difference in the overall response between the two treatment g ... | 2005 | 15727921 |
| a comparison of adherence by four strains of staphylococcus intermedius and staphylococcus hominis to canine corneocytes collected from normal dogs and dogs suffering from atopic dermatitis. | the aim of this study was to compare the adherence of four strains of staphylococcus intermedius and a single strain of staphylococcus hominis to corneocytes from both normal dogs and dogs suffering from atopic dermatitis. cells from the skin surface, corneocytes, were collected from 10 normal dogs and 10 dogs suffering from atopic dermatitis. four strains of s. intermedius, three isolated from canine pyoderma skin lesions (strains a, b and c), and one isolated form from canine synovial membrane ... | 2005 | 15766937 |
| thermonuclease gene as a target for specific identification of staphylococcus intermedius isolates: use of a pcr-dna enzyme immunoassay. | a pcr-dna enzyme immunoassay (pcr-deia) was developed for identification of the coagulase-positive species staphylococcus intermedius. two pcr primers and a hybridization probe were designed to target specific sequences of the s. intermedius thermonuclease (nuc) gene. in addition to s. intermedius reference strains, the pcr-deia was tested using 295 veterinary and human s. intermedius isolates. a specific 933-bp dna fragment was successfully amplified in 281 (94.9%) s. intermedius isolates. five ... | 2005 | 15808314 |
| [review on the etiology and treatment of bacterial pneumonias]. | the bacterial pneumoniae are the significant factor of morbidity and mortality all over the world. so usa are at the sixth place per mortality cause. the bacteria are in 60-80% of cases the causes of pneumonia in the communities. therefore this is the review on the ethiology of the verification and treatment of pneumonias in the 17-month period in the general hospital "sarajevo". in the period of the 1st january 2002 till the 31st may 2003 year, it was examined 105 sputa on the antibiogram, and ... | 2005 | 15822680 |
| staphylococcus intermedius produces a functional agr autoinducing peptide containing a cyclic lactone. | the agr system is a global regulator of accessory functions in staphylococci, including genes encoding exoproteins involved in virulence. the agr locus contains a two-component signal transduction module that is activated by an autoinducing peptide (aip) encoded within the agr locus and is conserved throughout the genus. the aip has an unusual partially cyclic structure that is essential for function and that, in all but one case, involves an internal thiolactone bond between a conserved cystein ... | 2005 | 15838041 |
| avian tuberculosis in a wild turkey. | a liver from a hunter-harvested wild turkey (meleagris gallopavo) from kansas was evaluated by the southeastern cooperative wildlife disease study. grossly, the liver contained several grayish-white masses ranging from 0.5-3 cm in diameter. these masses were scattered throughout the parenchyma and bulged from the capsular surface. histologic examination revealed multifocal to coalescing granulomas with low numbers of acid-fast bacilli within multinucleated giant cells at the periphery of the gra ... | 2005 | 15839433 |
| investigations into the basis of chloramphenicol and tetracycline resistance in staphylococcus intermedius isolates from cases of pyoderma in dogs. | a total of 160 staphylococcus intermedius isolates were recovered from cases of pyoderma in 2002 and were examined for susceptibility to 13 different antimicrobial agents. ninety per cent (144) of the isolates were resistant to tetracycline, derivatives of which have been used until recently, and 18% (29) were resistant to chloramphenicol which was banned from use 13 years ago. the presence of genes encoding chloramphenicol acetyltransferase (cat) and tetracycline resistance (tet); tet(k), (l), ... | 2005 | 15876223 |
| molecular characterization of staphylococcus intermedius carriage by healthy dogs and comparison of antimicrobial susceptibility patterns to isolates from dogs with pyoderma. | we conducted an epidemiological study of staphylococcus intermedius using arbitrarily primed pcr (ap-pcr) and antibiograms. one hundred and twenty-five s. intermedius isolates were recovered from the oral cavity and/or cranial hair coat of healthy dogs enrolled in a pet therapy program. commensal s. intermedius was cultured from 32% of the oral cavity cultures and 13% of the cranial hair coat cultures. we characterized the colonization of the dogs as transient, intermittent, or persistent. for d ... | 2005 | 15917140 |
| leucocytoclastic vasculitis associated with staphylococcus intermedius in the pastern of a horse. | a pregnant quarterhorse mare became acutely lame as a result of severe swelling of its right hind leg, thought to have been caused by a fracture or a muscle tear. diagnostic procedures ruled out a traumatic musculoskeletal cause and a physical examination revealed chronic pastern dermatitis ('scratches'/'grease heel'). histopathological evaluation of biopsy samples from the right hind leg was consistent with a leucocytoclastic vasculitis, and culture yielded staphylococcus intermedius. the treat ... | 2005 | 15937241 |
| brain abscess caused by staphylococcus intermedius. | 2005 | 15605196 | |
| prospective study of bacterial overgrowth syndrome in eight dogs. | eight dogs with cutaneous lesions, clinical signs and cytological findings compatible with bacterial overgrowth syndrome were compared with four healthy dogs. the affected dogs were treated for 28 days with 30 mg/kg/day cephalexin. the results showed that the syndrome was a superficial cutaneous disorder characterised by marked pruritus, greasy seborrhoea, offensive odour, erythema, lichenification, hyperpigmentation, excoriations and alopecia involving principally the ventral aspect of the body ... | 2006 | 16581994 |
| comparison of pharmacodynamic and pharmacokinetic indices of efficacy for 5 fluoroquinolones toward pathogens of dogs and cats. | fluoroquinolones are often used interchangeably in dogs and cats. | 2006 | 17186841 |
| methicillin-resistant staphylococcal colonization in clinically normal dogs and horses in the community. | to evaluate the prevalence of methicillin-resistant staphylococcal (mrs) colonization in clinically normal dogs and horses in the community. | 2006 | 17083704 |
| efficacy of orbifloxacin tablets for the treatment of superficial and deep pyoderma due to staphylococcus intermedius infection in dogs. | orbifloxacin tablets were administered orally to 23 dogs with superficial and/or deep staphylococcal pyoderma. response to therapy was excellent in 95.6% of the dogs. duration of therapy varied from 21 to 40 days (average 29 days) for dogs having only superficial infections, and from 25 to 150 days (average 72 days) for dogs having deep infections. relapses occurred in 18% of the dogs within a 3-month period. one dog developed a presumed adverse cutaneous drug reaction. under the conditions of t ... | 2006 | 17078249 |
| in vitro activity of an ear rinse containing tromethamine, edta, and benzyl alcohol on bacterial pathogens from dogs with otitis. | to evaluate the in vitro activity of an ear rinse (er) containing tromethamine, edta, and benzyl alcohol on bacterial pathogens from dogs with otitis. | 2006 | 16740099 |
| genotypic relatedness of staphylococcal strains isolated from pustules and carriage sites in dogs with superficial bacterial folliculitis. | to determine whether staphylococcal isolates cultured from pustules and carriage sites in dogs with superficial bacterial folliculitis were genotypically the same strain by use of pulsed-field gel electrophoresis (pfge). | 2006 | 16881845 |
| comparison of susceptibility to antimicrobials of bacterial isolates from companion animals in a veterinary diagnostic laboratory in canada between 2 time points 10 years apart. | the susceptibility to antimicrobials of bacterial species most frequently isolated from companion animals in a veterinary teaching diagnostic laboratory was evaluated retrospectively. a significant decrease between 1990-1992 and 2002-2003 was noted in the susceptibility of dog isolates to the following antimicrobials: escherichia coli to cephalothin (86% to 61%, p < 0.001); e. coli to ampicillin (85% to 67%, p < 0.001); proteus spp. to ampicillin (92% to 71%, p < 0.01); coagulase-positive staphy ... | 2006 | 16933555 |
| comparison of tests to detect oxacillin resistance in staphylococcus intermedius, staphylococcus schleiferi, and staphylococcus aureus isolates from canine hosts. | multiple tests were compared to the reference standard pbp2a latex agglutination test for detection of meca-mediated oxacillin resistance in canine staphylococci. cefoxitin disk diffusion, using breakpoints for human isolates of coagulase-negative staphylococcus spp., had low sensitivity for detection of oxacillin resistance in members of the staphylococcus intermedius group. | 2006 | 16954277 |
| screening of staphylococcus aureus, staphylococcus intermedius, and staphylococcus schleiferi isolates obtained from small companion animals for antimicrobial resistance: a retrospective review of 749 isolates (2003-04). | companion animal staphylococcal isolate antibiograms were screened retrospectively to determine the frequency of methicillin-resistant (mr) infection by staphylococcus aureus, staphylococcus intermedius, and staphylococcus schleiferi. rates of mr were: s. aureus 35%, s. intermedius 17%, and s. schleiferi 40%. frequency of isolation of methicillin-resistant s. aureus (mrsa) from dogs and cats was similar, whereas methicillin-resistant s. intermedius (mrsi) and methicillin-resistant s. schleiferi ... | 2006 | 16961819 |
| otoscopic, cytological, and microbiological examination of the equine external ear canal. | otoscopic examination and cytology of the equine ear would be beneficial in diseases such as head trauma, headshaking, otitis externa secondary to otitis media, vestibular disease, aural neoplasia and aural pruritus secondary to parasites. in practice, otic examinations of horses are rarely done due to the perceived difficulty in visualizing the equine external ear canal and tympanic membrane, as well as the need for chemical restraint. in this study, the proximal external ear canal was examined ... | 2006 | 16674732 |
| antimicrobial activity and spectrum of cefovecin, a new extended- spectrum cephalosporin, against pathogens collected from dogs and cats in europe and north america. | cefovecin is a new extended-spectrum semisynthetic cephalosporin indicated for the treatment of bacterial infections in dogs and cats. this study evaluated the in vitro activity and spectrum of cefovecin against 2,641 recent clinical isolates (1,660 canine and 981 feline isolates) from europe and the united states. mic determinations against cefovecin and other reference antimicrobials were performed by broth microdilution methods recommended by the clinical and laboratory standards institute (c ... | 2006 | 16801403 |
| accessory gene regulator locus of staphylococcus intermedius. | the accessory gene regulator (agr) locus, a candidate system for the regulation of the production of virulence factors in staphylococcus intermedius, has been characterized. using pcr-based genome walking, we have obtained the first complete sequence (3,436 bp) of the accessory gene regulator (agr) gene in this organism. sequence analysis of the agr gene has identified five open reading frames (orfs), agrb, agrd, agrc, agra, and hld. the translated orf contained amino acid motifs characteristic ... | 2006 | 16622233 |
| [zoonotic importance of selected species of gram-positive bacteria.] | zoonoses continue to play a signicant role in both human and veterinary medicine. their eradication is difficult and some authors are convinced of their growing importance. among the pathogens of infectious diseases transmissible from animals to man are several gram-positive bacteria. the authors focus on three agents that present a risk in three different areas-alimentary infections (listeria monocytogenes), professional infections (streptococcus suis) and infections of breeders of so-called pe ... | 2006 | 16508905 |
| adherence by staphylococcus intermedius to canine corneocytes: a preliminary study comparing noninflamed and inflamed atopic canine skin. | the adherence by three strains of staphylococcus intermedius to corneocytes collected from healthy dogs was compared to the adherence to corneocytes collected from the inflamed (erythematous) and noninflamed (normal appearing) skin of dogs suffering from atopic dermatitis. all three strains of s. intermedius adhered in greater numbers to corneocytes from both inflamed and noninflamed atopic skin than to corneocytes from healthy dogs. adherence was greatest to corneocytes from inflamed atopic ski ... | 2006 | 16515659 |
| prevalence of virulence factors in staphylococcus intermedius isolates from dogs and pigeons. | staphylococcus intermedius has been isolated from healthy dogs and pigeons as well as diseased dogs. similar to staphylococcus aureus, s. intermedius is known to carry many virulence factors but most of these factors remain to be studied. in this study, we examined 106 s. intermedius isolates (44 dog isolates and 62 pigeon isolates) for their hemolytic activity, biofilm formation, protease activity, and clumping factor and protein a production. | 2006 | 16438708 |
| evaluation of clinical characteristics and bacterial isolates in dogs with bacterial keratitis: 97 cases (1993-2003). | to evaluate clinical characteristics and breeds affected with bacterial keratitis and compare patterns of resistance in bacterial isolates over time in dogs. | 2006 | 16426172 |
| masked, controlled study to investigate the efficacy of a staphylococcus intermedius autogenous bacterin for the control of canine idiopathic recurrent superficial pyoderma. | a masked, controlled study was designed to investigate the clinical efficacy of a staphylococcal autogenous bacterin for the control of canine idiopathic recurrent pyoderma (irp). ten dogs with at least three prior episodes of recurrent superficial pyoderma were recruited. all were screened and found to be free of ectoparasitic and fungal disease and failed to respond favourably to a dietary trial. those exhibiting signs of pruritus responded completely to antibacterial therapy. haematological a ... | 2006 | 16674730 |
| pharmacokinetics and pharmacodynamics of cefovecin in dogs. | a series of in vivo, ex vivo and in vitro studies were conducted to determine the pharmacokinetic and pharmacodynamic properties of cefovecin, a new injectable cephalosporin, in dogs. absolute bioavailability was determined in a two-phase cross-over study in dogs receiving 8 mg/kg bodyweight (b.w.) of cefovecin by either subcutaneous (s.c.) or intravenous (i.v.) route. after s.c. administration, cefovecin was fully bioavailable (100%), the mean maximum plasma concentration (cmax) was 121 microg/ ... | 2006 | 17083454 |
| dissemination of the gene encoding exfoliative toxin of staphylococcus intermedius among strains isolated from dogs during routine microbiological diagnostics. | phenotypic properties and species-specific pcr tests based on the nuc gene of staphylococcus intermedius and s. aureus, and a conserved region of 16s rdna were used to identify 45 s. intermedius and four s. aureus isolated from samples of dogs during routine diagnostics. four s. pseudintermedius strains used for control purposes reacted positively with the s. intermedius nuc pcr showing the close relationship between both species. investigating the 45 s. intermedius and four s. pseudintermedius ... | 2006 | 17062121 |
| experimental staphylococcal mastitis in bitches: clinical, bacteriological, cytological, haematological and pathological features. | the objectives of the work were to study the features of experimentally induced canine mastitis and to present hypotheses regarding the pathogenesis of the disease. the right caudal abdominal mammary gland of six bitches was inoculated on day 8 after whelping with staphylococcus intermedius to induce mastitis; adjacent mammary glands were used as controls. clinical examination, bacteriological and cytological (whiteside test, giemsa) examination of mammary secretion, as well as haematological te ... | 2007 | 17481831 |
| population genetic structure of the staphylococcus intermedius group: insights into agr diversification and the emergence of methicillin-resistant strains. | the population genetic structure of the animal pathogen staphylococcus intermedius is poorly understood. we carried out a multilocus sequence phylogenetic analysis of isolates from broad host and geographic origins to investigate inter- and intraspecies diversity. we found that isolates phenotypically identified as s. intermedius are differentiated into three closely related species, s. intermedius, staphylococcus pseudintermedius, and staphylococcus delphini. s. pseudintermedius, not s. interme ... | 2007 | 17905991 |
| first report of multiresistant, meca-positive staphylococcus intermedius in europe: 12 cases from a veterinary dermatology referral clinic in germany. | resistance to cephalosporins and/or fluoroquinolones by staphylococcus intermedius has remained low in europe, with effective drugs generally available for systemic therapy in pets. however, multiresistant, meca-positive s. intermedius isolated from dogs and cats is now emerging in europe. twelve s. intermedius isolates, highly resistant to at least five antimicrobial classes, were isolated from skin and ear infections in 11 dogs and a cat. the 12 isolates represented 23% of all s. intermedius s ... | 2007 | 17991158 |
| molecular basis of resistance to macrolides and lincosamides among staphylococci and streptococci from various animal sources collected in the resistance monitoring program bft-germvet. | in this study, erythromycin- and/or clindamycin-resistant isolates among 248 coagulase-positive and coagulase-variable staphylococci and 500 streptococci, collected all over germany during 2004-2006 in the resistance monitoring program bft-germvet, were investigated for their genetic basis of macrolide and/or lincosamide resistance. staphylococci were sampled from various disease conditions of dogs/cats or pigs, whereas streptococci were from dogs/cats, pigs or horses. resistant staphylococci we ... | 2007 | 17307339 |
| species distribution and properties of staphylococci from canine dermatitis. | the occurrence and phenotypic, and genotypic properties of 24 staphylococcus isolates from canine dermatitis were investigated. the predominant staphylococcal species was staphylococcus intermedius. the other species such as staphylococcus chromogenes, staphylococcus sciuri, staphylococcus aureus, staphylococcus saprophyticus, staphylococcus epidermidis, and staphylococcus capitis were only occasionally isolated. the study showed low level biochemical diversity among s. intermedius isolates. res ... | 2007 | 17126372 |
| phenotypic and genotypic characteristics of methicillin/oxacillin-resistant staphylococcus intermedius isolated from clinical specimens during routine veterinary microbiological examinations. | methicillin/oxacillin resistance of 10 s. intermedius strains was investigated by conventional and molecular methods. the strains tested had been isolated in germany during routine veterinary microbiological examinations of specimens from a small animal clinic between may and september 2005. epidemiological relationships of the strains were studied by macrorestriction analysis of their chromosomal dna using pulsed field gel electrophoresis (pfge). species identity of the 10 s. intermedius strain ... | 2007 | 17174042 |
| staphylococcal and micrococcal adherence to canine and feline corneocytes: quantification using a simple adhesion assay. | in this paper a simple adhesion assay suitable for the assessment of bacterial adhesion to both canine and feline corneocytes is described. using this assay staphylococcus intermedius, staphylococcus aureus and staphylococcus chromogenes were shown to adhere well to both canine and feline corneocytes. the numbers of adherent bacteria were, however, generally lower for feline corneocytes. both staphylococcus hominis and a micrococcus species adhered poorly to canine and feline corneocytes. this i ... | 2007 | 17222237 |
| characterization of a variant of the sccmec element in a bloodstream isolate of staphylococcus intermedius. | here we report for the first time, a detailed characterization of a variant of the sccmec element, in a methicillin-resistant staphylococcus intermedius human isolate. s. intermedius is a coagulase-positive zoonotic microrganism, recently classified as a separate species. in routine clinical laboratory practice, the coagulase production is used as criterion of pathogenicity related to s. aureus, but s. intermedius is frequently misidentified-being mistaken for s. aureus-and consequently its real ... | 2007 | 17536928 |
| surgical treatment of a vertebral fracture associated with a haematogenous osteomyelitis in a dog. | a seven-month-old rottweiler was referred for a diagnosed femoral neck fracture and a suspected vertebral fracture. the simplified neurological examination revealed an acute paraplegia. a discospondyilitis associated with a pathologic fracture of th11 and a spinal compression, and a haematogenous epiphysitis of the femoral neck were diagnosed based on radiographic and computed tomographic examinations. the vertebral fracture was stabilised using screws and polymethylmetacrylate with gentamycin b ... | 2007 | 17846691 |
| surveillance of healthy cats and cats with inflammatory skin disease for colonization of the skin by methicillin-resistant coagulase-positive staphylococci and staphylococcus schleiferi ssp. schleiferi. | in this study, bacterial cultures were collected from five sites on each of 50 healthy cats and 48 cats with inflammatory skin disease (isd), to determine prevalence of carriage and relative frequency of methicillin resistance in coagulase-positive staphylococci and staphylococcus schleiferi ssp. schleiferi. latex agglutination testing for penicillin-binding protein 2a (pbp2a) and pulsed field gel electrophoresis (pfge) were performed on all methicillin-resistant (mr) isolates. polymerase chain ... | 2007 | 17610491 |
| staphylococcus-induced urolithiasis in estrogen-treated ovariectomized nude mice. | nine of 24 ovariectomized nude mice developed ulcerative skin lesions 28 d after implantation with human breast cancer cells and slow-release estrogen pellets. aerobic culture of samples from the skin lesions yielded staphylococcus intermedius. by day 45 postimplantation, all mice displayed ulcerative skin lesions, and 5 mice exhibited hunched posture, listless behavior, cyanosis, anorexia, and dehydration. this subset was euthanized but not necropsied. when additional animals became moribund, t ... | 2007 | 17645298 |
| antimicrobial susceptibility and mechanism of resistance to fluoroquinolones in staphylococcus intermedius and staphylococcus schleiferi. | the objective of the present study was to determine the antimicrobial susceptibility of 136 canine isolates of staphylococcus intermedius and 10 canine isolates of s. schleiferi subspecies coagulans to 16 fluoroquinolones (fqs), and to investigate the mechanisms of resistance in the nonsusceptible isolates. of the 136 of s. intermedius tested 98.5% were susceptible to all 16 fqs whereas only 40% of the 10 isolates of s. schleiferi subspecies coagulans were susceptible. two isolates of s. interme ... | 2007 | 17803740 |
| reclassification of phenotypically identified staphylococcus intermedius strains. | to reclassify phenotypically identified staphylococcus intermedius strains, which might include true s. intermedius strains and novel species such as staphylococcus pseudintermedius and staphylococcus delphini, we analyzed molecular phylogenies and phenotypic characteristics of 117 s. intermedius group (sig) strains tentatively identified as being s. intermedius by the rapid id32 staph assay. from phylogenetic analyses of soda and hsp60 sequences, the sig strains were divided into three clusters ... | 2007 | 17596353 |
| high occurrence of multi-antimicrobial resistance in staphylococcus intermedius isolates from healthy and diseased dogs and domesticated pigeons. | staphylococcus intermedius isolates (n=106), including 44 dog isolates and 62 pigeon isolates, were examined for their susceptibility to ampicillin, cephalexin, erythromycin, gentamicin, kanamycin, lincomycin, norfloxacin, oxacillin, tetracycline, and vancomycin by standard disk-diffusion test. the frequencies of resistance to ampicillin, kanamycin, and tetracycline were significantly higher in dog isolates than pigeon isolates (95.5% vs. 0%, 31.8% vs. 0%, and 45.5% vs. 9.7%, respectively; p<0.0 ... | 2007 | 17368493 |
| in vitro antimicrobial activity of the leaf extract of harungana madagascariensis lam. ex poir. (hypericaceae) against strains causing otitis externa in dogs and cats. | otitis externa in dogs and cats is always caused by a combination of yeasts and bacteria, among which the most important are malassezia pachydermatis, staphylococcus intermedius and pseudomonas species. these organisms often develop resistance to classical antimicrobial agents. therefore, the aim of this study was to investigate the antimicrobial activities of an ethyl acetate leaf extract of harungana madagascariensis against the organisms cited, to carry out the phytochemical investigation of ... | 2007 | 17385560 |
| identification and antimicrobial susceptibility of bacteria and yeasts isolated from healthy dogs and dogs with otitis externa. | the bacterial and fungal flora of the external ear canal of dogs with otitis externa and of healthy dogs were studied. the most frequently isolated microorganism from otitic ears was staphylococcus intermedius (58.8%), followed by malassezia pachydermatis (30.9%), streptococcus canis (29.9%), proteus spp. (14.4%) and escherichia coli (10.3%). a statistical analysis of our results showed that the prevalence of these microorganisms is significant in dogs with otitis externa. furthermore, the antim ... | 2007 | 18045339 |
| occurrence of antimicrobial resistance in bacteria from diagnostic samples from dogs. | to study the occurrence of antimicrobial resistance among common bacterial pathogens from dogs and relate resistance patterns to data on consumption of antimicrobials. | 2007 | 17644533 |
| reservoirs of antimicrobial resistance in pet animals. | increasing amounts of antimicrobials are used in pets, including substances used in human medicine (in particular, broad-spectrum agents such as clavulante-potentiated aminopenicillins, cephalosporins, and fluoroquinolones). there is evidence that resistance to antimicrobials is growing among bacteria causing infection in pets. these bacteria include staphylococcus intermedius and escherichia coli, as well as other organisms of clinical importance in humans, including methicillin-resistant staph ... | 2007 | 17683019 |
| pyelonephritis associated with staphylococcus intermedius in a siberian tiger (panthera tigris altaica). | pyelonephritis, in which staphylococcus intermedius was isolated, was diagnosed in a 4-year-old female siberian tiger (panthera tigris altaica). at necropsy, the renal pelvis was dilated with a large amount of purulent exudates. microscopically, the lesions of renal pelvis and medulla consisted of necrotic foci intermingled primarily with numerous degenerative neutrophils and a few lymphocytes, plasma cells and macrophages. bacteriology showed the presence of s. intermedius. this is the first re ... | 2007 | 17827895 |
| prevalence of oxacillin- and multidrug-resistant staphylococci in clinical samples from dogs: 1,772 samples (2001-2005). | to determine whether resistance to oxacillin and other antimicrobials in 3 staphylococcus spp commonly isolated from dogs increased from 2001 to 2005. | 2007 | 17223755 |
| microbiological and histopathological features of canine acral lick dermatitis. | the purpose of this study was to investigate microbiological and histopathological features of canine acral lick dermatitis (ald). microbial characteristics of ald are poorly described in current literature. if infection is recognized, antimicrobial selection is usually empirical, based on appearance, cytology or surface culture, rather than deep tissue culture. it was hypothesized that cultures obtained from deep tissue would yield different results than predicted by surface culture and cytolog ... | 2008 | 18699812 |
| immunoglobulin g responses in 21 dogs with skin diseases to antigens from different isolates of staphylococcus intermedius. | the aim of this study was to characterise the immunoglobulin g (igg) response in 21 dogs with or without pyoderma to antigens from six isolates of staphylococcus intermedius. the staphylococcal proteins were separated by sodium dodecyl sulphate polyacrylamide gel electrophoresis, transferred electrophoretically on to a membrane and subjected to immunoblotting with the dogs' serum. gels containing separated proteins from the six isolates revealed 29 to 33 distinct bands with molecular weights ran ... | 2008 | 18204030 |
| susceptibility of canine and feline escherichia coli and canine staphylococcus intermedius isolates to fluoroquinolones. | 1) a prospective study to determine in vitro concentrations for a range of fluoroquinolones, gentamicin and amoxycillin-clavulanate required to inhibit growth of recently collected, feline and canine escherichia coli and canine staphylococcus intermedius isolates. 2) a comparative retrospective study to compare the minimum inhibitory concentrations (mics) of ciprofloxacin, enrofloxacin and amoxycillin-clavulanate for archived canine e coli and s intermedius isolates collected ten to twenty years ... | 2008 | 18363989 |
| bovine mastitis and antibiotic resistance patterns in selalle smallholder dairy farms, central ethiopia. | a study was conducted to determine the prevalence of mastitis, identify the major bacterial pathogens and test the antimicrobial resistance of milk bacterial isolates in smallholder dairy farms in selalle area, ethiopia. a total of 109 smallholder dairy farms comprising 500 crossbred lactating cows were included. the prevalence of clinical mastitis at herd, cow and quarter level was 8.3% (n=9), 1.8% (n=9) and 0.51% (n=10), respectively, while that of sub-clinical mastitis was 54.7%, 22.3% and 10 ... | 2008 | 18557189 |
| comparative study of the microbial profile from bilateral canine otitis externa. | fifty dogs with bilateral otitis externa were studied over a 10-month period. the exudates of both external ears were obtained, using sterile swabs, and microorganisms were isolated according to standard microbiological techniques. antimicrobial susceptibility testing of staphylococcus intermedius was done by the agar diffusion method. there was bacterial and/or fungal growth in all of the samples. these were all polymicrobial infections. anaerobic bacteria were not isolated in any sample. the m ... | 2008 | 18978972 |
| antimicrobial resistance and prevalence of canine uropathogens at the western college of veterinary medicine veterinary teaching hospital, 2002-2007. | between january 2002 and june 2007, uropathogens were isolated from 473 of 1557 canine urine samples submitted to prairie diagnostic services from the western college of veterinary medicine veterinary teaching hospital. culture and susceptibility results were analyzed, retrospectively, to estimate the prevalence of common bacterial uropathogens in dogs with urinary tract infections and to identify changes in antimicrobial resistance. the most common pathogens identified were escherichia coli, st ... | 2008 | 19119366 |
| characterization of staphylococcus species isolated from raw milk and milk products (lben and jben) in north morocco. | to investigate the incidence and antibiotic resistance of staphylococcal strains isolated from milk and milk products and to trace the ecological origin of the staphylococcus aureus isolated. | 2008 | 19738354 |
| methicillin-resistant staphylococcal colonization in dogs entering a veterinary teaching hospital. | nasal, axillary and rectal swabs were collected from 193 dogs admitted to the ontario veterinary college veterinary teaching hospital. enrichment culture was performed and coagulase positive staphylococci were identified via standard methods. methicillin-resistant staphylococcus pseudintermedius was isolated from 4/193 (2.1%) dogs, and methicillin-resistant staphylococcus aureus and methicillin-resistant staphylococcus schleiferi subsp. coagulans were each isolated from 1/193 (0.5%) dogs. methic ... | 2008 | 17643874 |
| synergistic effects of miconazole and polymyxin b on microbial pathogens. | the therapeutic value of antibiotics depends on the susceptibility of the infecting microorganism and the pharmacological profile of the drugs. to assess the value of an antibiotic combination of polymyxin b and miconazole this study examined the in vitro synergistic potential of the two drugs on gram-negative and gram-positive bacteria and yeast. antifungal and antibacterial activity was tested by minimum inhibitory concentration (mic) of broth macrodilution and urea broth microdilution, by flu ... | 2008 | 19085068 |
| occurrence of staphylococci in the oral cavities of healthy adults and nasal oral trafficking of the bacteria. | to investigate a possible peroral route of infective endocarditis (ie), the occurrence of staphylococci in the oral cavity was examined using saliva and supragingival plaque specimens from 56 systemically and periodontally healthy adults aged 22-43 years old (27.1+/-5.3). nine staphylococcus species and 334 isolates were identified. in saliva, the total occurrence rate was 83.9 % and the total number of bacteria was 10(2)-10(4) c.f.u. ml(-1). staphylococcus aureus was the most frequent species ( ... | 2008 | 18065673 |
| transmission of methicillin-resistant staphylococcus intermedius between humans and animals. | 2008 | 18164147 | |
| relevance of hot spots in the evolution and transmission of tn1546 in glycopeptide-resistant enterococcus faecium (gref) from broiler origin. | glycopeptide-resistant enterococci are still present within the broiler sector, despite the eu ban of avoparcin more than a decade ago. in the present study, we have developed a rapid method for screening the flanking regions at the integration point of tn1546 in glycopeptide-resistant enterococcus faecium isolated from broiler farms. | 2008 | 18583326 |
| an experimental in-vivo canine model for adult shunt infection. | abstract: | 2008 | 18950490 |
| comparative in vitro antimicrobial efficacy of commercial ear cleaners. | the aim of this study was to compare the antimicrobial efficacy of ear cleaners against staphylococcus intermedius, pseudomonas aeruginosa and malassezia pachydermatis. single isolates of each organism were incubated in duplicate at 38 degrees c for 30 min with each ear cleaner diluted 1/2 to 1/256 in phosphate-buffered saline. positive and negative controls were included. aliquots were then incubated for 16-18 h on sheep blood agar (bacteria) or for 3 days on sabouraud's dextrose agar (malassez ... | 2008 | 19055612 |
| methicillin-resistant commensal staphylococci in healthy dogs as a potential zoonotic reservoir for community-acquired antibiotic resistance. | beta-lactam-resistant staphylococci evolved due to widespread nosocomial antibiotic use during the twentieth century, but the last decade has seen the emergence of genotypically distinct resistant bacteria outside hospitals, such as community-acquired methicillin-resistant staphylococcus aureus (ca-mrsa). this changing epidemiology suggests that mechanisms other than direct antibiotic selection could be involved in the spread of bacterial resistance. here we report a 17% prevalence of methicilli ... | 2009 | 19073283 |
| antibiotic resistance patterns and occurrence of meca gene in staphylococcus intermedius strains of canine origin. | we have evaluated 102 staphylococcus intermedius isolates of canine origin for susceptibility to antimicrobial primary agents, i.e. penicillin, amoxicillin, amoxicillin with clavulanic acid, cefuroxime, trimethoprim/sulfonamides, neomycin, streptomycin, gentamicin, norfloxacin, tetracycline, vancomycin, erythromycin and secondary agents, i.e., chloramphenicol, ciprofloxacin, lincomycin, teicoplanin, rifampicin, imipenem, mupirocin. antimicrobial sensitivity was examined using the disk diffusion ... | 2009 | 19459434 |
| staphylococcal colonization of mucosal and lesional skin sites in atopic and healthy dogs. | staphylococcal colonization was compared in healthy dogs and in dogs with atopic dermatitis. bacterial swabs were collected from the nasal mucosa, ear and perineum of 43 healthy and 24 atopic dogs and also from potentially infected skin lesions of the atopic dogs. coagulase positive staphylococcal isolates were identified to the species level. at the time of this study staphylococcus intermedius was considered a single species but has since been recognized as comprising at least three species wi ... | 2009 | 19392768 |
| interventions for control of salmonella: clearance of microbial growth from rubber picker fingers. | a study was conducted to determine if a surface material with antimicrobial properties combined with an effective disinfectant could achieve total clearance of bacterial contamination. before beginning the project, new rubber picker fingers collected from 3 processing facilities were tested for endogenous microflora. five species of bacteria common to soil and human handling were present: bacillus amyloliquefaciens, bacillus cereus/thuringiensis, staphylococcus epidermidis, staphylococcus homini ... | 2009 | 19439642 |
| integration of pharmacokinetic and pharmacodynamic indices of orbifloxacin in beagle dogs after a single intravenous and intramuscular administration. | the pharmacokinetics (pk) and pharmacodynamics (pd) of orbifloxacin were studied in beagle dogs after intravenous (i.v.) and intramuscular (i.m.) administration at a dose of 2.5 mg/kg body weight. an absolute bioavailability of 100.1% +/- 4.76%, a terminal half-life of 4.23 +/- 0.2 h and 3.95 +/- 0.15 h after i.v. and i.m. administration, a steady-state volume of distribution of 1.61 +/- 0.13 liters/kg, and clearance of 0.31 +/- 0.03 liters/h/kg were observed. orbifloxacin showed rapid, concentr ... | 2009 | 19398644 |
| evaluation of mucosal and seborrheic sites for staphylococci in two populations of captive psittacines. | to survey 2 populations of psittacines to characterize staphylococcus spp isolated from commensal cutaneous microflora. | 2009 | 19335240 |
| management of human and animal bite wound infection: an overview. | animal and human bite wounds can lead to serious infections. the organisms recovered generally originate from the biter's oral cavity and the victim's skin flora. anaerobes were isolated from more than two thirds of human and animal bite infections. streptococcus pyogenes is often recovered in human bites, pasteurella multocida in animal bites, eikenella corrodens in animal and human, capnocytophaga spp, neisseria weaveri, weeksella zoohelcum, neisseria canis, staphylococcus intermedius, nonoxid ... | 2009 | 19698283 |