Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| restriction fragment length polymorphisms detected by anonymous dna probes mapped to defined intervals of human chromosome 16. | three anonymous dna probes ach207, ach224, and ach202, isolated from a flow-purified chromosome 16 library and mapped to defined intervals of human chromosome 16, detected restriction fragment length polymorphisms (rflps). the rflps were of simple two allele types. the ach207 (d16s4) probe detected a taqi and an mspi rflp with polymorphism information content (pic) values of 0.30 and 0.27; the ach224 (d16s5) probe detected an rsai rflp, pic value of 0.34; and the ach202 (d16s4) probe detected an ... | 1988 | 2900214 |
| tubulin post-translational modifications and the construction of microtubular organelles in trypanosoma brucei. | we have used specific monoclonal antibodies to facilitate a study of acetylated and tyrosinated alpha-tubulin in the microtubule (mt) arrays in the trypanosoma brucei cell. acetylated alpha-tubulin is not solely located in the stable microtubular arrays but is present even in the ephemeral microtubules of the mitotic spindle. moreover, there is a uniform distribution of this isoform in all arrays. studies of flagella complexes show that acetylation is concomitant with assembly of mts. there is n ... | 1988 | 3075618 |
| hypoperfusion-induced acute renal failure in the rat: an evaluation of oxidant tissue injury. | reactive oxygen species (ros) have been reported to be critical cellular mediators of experimental ischemic acute renal failure (arf). this conclusion is based on observations that in the renal artery occlusion (rao) model of arf, antioxidant drugs confer protection and that renal malondialdehyde (mda) concentrations, an index of lipid peroxidation, rise in the postischemic period. human ischemic arf is most often due to hypoperfusion, not to total blood flow interruption. therefore, the goal of ... | 1988 | 3124972 |
| coamplification of the hst-1 and int-2 genes in human cancers. | the hst-1 gene, previously designated the hst gene, was identified as a transforming gene by transfection assays of genomic dnas from various types of human cancers. we analyzed for alterations of the hst-1 gene in 18 bladder cancers, 23 renal cell carcinomas and 5 esophageal cancers. although rearrangement of the gene was not detected in any of these samples, amplification of the hst-1 gene was found in 4 samples of tumors, including an invasive bladder cancer, both primary esophageal cancer an ... | 1988 | 3133332 |
| periodontal changes after experimentally induced intrusion of the upper incisors in macaca fuscata monkeys. | we are studying the biologic aspects of vertical movement of teeth, which are often used in orthodontic treatment involving variations in alveolar tissue. in the present study, the four upper incisors of five infant macaca fuscata monkeys were intruded vertically from 1.1 to 5.5 mm. the following effects were examined: (1) movement of the gingiva, (2) change in the depth of the gingival sulcus, and (3) microscopic effects on the alveolar tissue. the results were as follows. (1) the gingiva moved ... | 1989 | 2916468 |
| some physico-chemical properties of the rigid form of the sendai virus nucleocapsid. | the effect of some dissociation agents (sds, beta-mercaptoethanol, urea, edta) on the rigid form of the sendai virus nucleocapsid was studied. polyacrylamide gel electrophoresis in the presence of lytic mixture (1% sds, 2% beta-mercaptoethanol, 5 m urea, for 2 min at 100 degrees c) revealed two types of polypeptide subunits (mol. wts. 46,000 and 14,000), as well as the dissociation in the presence of 0.1% sds only. the edta treatment leads to a disorganization of the protein part (10(-2) m) or o ... | 1989 | 2556836 |
| effects of gestational exposure to phencyclidine: distribution and neurochemical alterations in maternal and fetal brain. | phencyclidine is a widely used drug of abuse and is known to produce a wide variety of psychoactive effects. pcp abuse by pregnant women has been reported to result in the birth of infants exhibiting irritability, jitteriness and hyperactivity with high pitched cries. the present study was designed to evaluate the distribution of pcp in the maternal and fetal brain and the neurochemical effects produced by gestational exposure. pregnant sprague-dawley rats were treated sc with 5 mg/kg pcp on 3 c ... | 1989 | 2576301 |
| serum igg level against streptococcus mutans in subjects with caries experience. | serum igg level against streptococcus mutans serotype c was studied in 33 subjects, in relation to dental caries, oral hygiene and age. the activity of the serum igg against the sonicated antigens of the bacterium was evaluated by micro-elisa. the serum igg titer to s. mutans was significantly higher in the subjects with no detectable carious lesions than in the subjects with active caries (p less than 0.05). however, there was no clear difference between the serum igg antibody to s. mutans and ... | 1989 | 2632131 |
| serum igg level against streptococcus mutans in subjects with caries experience. | serum igg level against streptococcus mutans serotype c was studied in 33 subjects, in relation to dental caries, oral hygiene and age. the activity of the serum igg against the sonicated antigens of the bacterium was evaluated by micro-elisa. the serum igg titer to s. mutans was significantly higher in the subjects with no detectable carious lesions than in the subjects with active caries (p less than 0.05). however, there was no clear difference between the serum igg antibody to s. mutans and ... | 1989 | 2632131 |
| study of cell kinetics in anaplastic thyroid carcinoma transplanted to nude mice. | the cell kinetics of the transplantable human anaplastic thyroid carcinoma were studied in athymic nude mice using bromodeoxyuridine (brdu) pulse labeling. in order to estimate the cell cycle time in this study, the percent labeled mitosis curve was prepared with immunoperoxidase staining using monoclonal antibody to brdu instead of 3[h]thymidine autoradiography. this technique was considered to be very useful because it can be done for a short term and can still be changed to the autoradiograph ... | 1989 | 2654483 |
| [synthetic cephalosporins. v. synthesis and antibacterial activity of 3-alkylthio-7 beta-[(z)-2-(2-aminothiazol-4-yl)-2-(o-substituted oxyimino)acetamido]cephalosporins and related compounds]. | 3-alkylthio-7 beta-[(z)-2-(2-aminothiazol-4-yl)-2-(o-substituted oxyimino)acetamido]cephalosporins (6 and 7) and the 3-methoxy analogues (10) were prepared by coupling diphenylmethyl 7-amino-3-alkylthio-3-cephem-4-carboxylate (1 and 2) or diphenylmethyl 7-amino-3-methoxy-3-cephem-4-carboxylate with (z)-2-(2-tritylaminothiazol-4-yl)-2-(o-substituted oxyimino)acetic acid (4), followed by deprotection and subjected to examination of antibacterial activities. the pivaloyloxymethyl esters (8 and 9) o ... | 1989 | 2698417 |
| san people (bushmen) from the central kalahari desert found free of antibodies to hiv-1 and hiv-2. | 1989 | 2754614 | |
| tamoxifen decreases the estradiol induced progesterone receptors by interfering with nuclear estrogen receptor accumulation. | the retention time of the estrogen receptor in the nucleus of target cells after antiestrogen treatment has been shown to be longer than after estradiol. this paper describes the accumulation of nuclear estrogen receptors and the obtention of estrogenic responses (i.e. synthesis of cytosolic progesterone receptors and dna) in the rat uterus after tamoxifen treatment in the presence or absence of estradiol. one-week ovariectomized adult rats were implanted with a silicone elastomer capsule contai ... | 1989 | 2761261 |
| decreased 3 alpha-androstanediol glucuronide levels in plasma and random urines in male pseudohermaphroditism caused by 5 alpha-reductase deficiency. | concentrations of 3 alpha-diol glucuronide (3 alpha-diol g) in plasma and/or random urine samples were determined in seven subjects with familial male pseudohermaphroditism (fmp) due to 5 alpha-reductase deficiency (5 alpha-rd). all subjects were natives of an isolated turkish village with a high incidence of consanguineous marriage. a specific and sensitive antibody to 3 alpha-diol was used for radioimmunoassay of 3 alpha-diol g after hydrolysis and chromatographic purification. the mean plasma ... | 1989 | 2770532 |
| amniotic oxytocin and vasopressin in relation to human fetal development and labour. | previous experiments in rats revealed increased amniotic oxytocin (oxt) levels in the course of normal development and increased vasopressin (avp) levels in retarded fetal growth. in order to see whether similar changes would also occur in human, oxt and avp levels were determined in amniotic fluid, maternal and fetal plasma before or during labour. positive correlations were found between umbilical avp levels on the one hand and gestation length, birth weight, placental weight and brain size on ... | 1989 | 2806154 |
| amniotic oxytocin and vasopressin in relation to human fetal development and labour. | previous experiments in rats revealed increased amniotic oxytocin (oxt) levels in the course of normal development and increased vasopressin (avp) levels in retarded fetal growth. in order to see whether similar changes would also occur in human, oxt and avp levels were determined in amniotic fluid, maternal and fetal plasma before or during labour. positive correlations were found between umbilical avp levels on the one hand and gestation length, birth weight, placental weight and brain size on ... | 1989 | 2806154 |
| p-glycoprotein and progesterone receptor in human breast cancer. | 1990 | 1974809 | |
| inhibition of nitric oxide synthase blocks n-methyl-d-aspartate-, quisqualate-, kainate-, harmaline-, and pentylenetetrazole-dependent increases in cerebellar cyclic gmp in vivo. | the synthesis of nitric oxide by brain slices has been demonstrated in several laboratories. in addition, in vitro studies have demonstrated stimulation of nitric oxide synthesis by excitatory amino acid receptor agonists. these data have led to the hypothesis that this readily diffusible "intercellular messenger molecule" acts to generate a cascade effect by activating guanylate cyclase in several cell types and thereby augment levels of the second messenger cyclic gmp (cgmp). therefore, we eva ... | 1990 | 1693947 |
| peptide regulation of adrenal medullary function. | the discovery of peptides in the splanchnic nerve and adrenal gland, and their co-existence with conventional neurotransmitters raises questions about their possible functional roles in catecholamine (ca) secretion and gene transcription in the adrenal gland. short-term, stress-induced ca secretion is regulated biphasically by substance p (sp) which inhibits acetylcholine (ach) action at sp greater than 10(-6) m and facilitates ca secretion in response to metabolic and physical stressors, ach or ... | 1990 | 1694230 |
| lack of pqq dependent glucose dehydrogenase apoenzyme in some acinetobacter spp. | seventy four asaccharolytic strains of acinotobacter were tested for the presence of pqq dependent glucose dehydrogenase apoenzyme. this apoenzyme could not be detected in any of five strains of acinetobacter haemolyticus; it was also lacking in one strain of each a. junii and a. lwoffi. | 1990 | 2176072 |
| hypoglycemia risk during exercise after intramuscular injection of insulin in thigh in iddm. | the influence of bicycle exercise (60% of w170 [working capacity at a pulse rate of 170 beats/min]; 40 min) on the absorption of 125i-labeled fast-acting insulin (10 u; actrapid human insulin) after intramuscular compared with subcutaneous injection in the thigh was studied on 2 consecutive days in 10 insulin-dependent diabetes mellitus (iddm) patients. insulin absorption was measured as disappearance of radioactivity (1st-order elimination rate constants) by continuous external monitoring and a ... | 1990 | 2190773 |
| structural specificity for biological activity of trichostatin a, a specific inhibitor of mammalian cell cycle with potent differentiation-inducing activity in friend leukemia cells. | biological activities of four chemically synthesized trichostatin-related compounds, (r)-trichostatin a, (s)-trichostatin a, (r)-trichostatic acid, and (s)-trichostatic acid, were investigated. assays of differentiation-inducing activity in friend leukemia cells and g2-arresting activity in the cell cycle of normal rat fibroblast cells were used as monitoring systems for comparing the bioactivities of these compounds. the results clearly showed that both of the enantiomers of trichostatic acid h ... | 1990 | 2211374 |
| [activity of neutral peptide hydrolases and oxidative enzymes in the myocardium and blood during hypoxic hypoxia]. | the citric cycle dehydrogenases and neutral peptide hydrolases (nph) activity was determined in the myocardium and blood serum of wistar rats under acute and prolonged hypoxic hypoxia. it was shown that the nph activity and the activity of the most oxidative enzymes change in the same direction during adaptation to the high-altitude conditions. the role of the nph in the oxidative metabolism reconstruction under acute and chronic hypoxia was discussed. | 1990 | 2238155 |
| [activity of neutral peptide hydrolases and oxidative enzymes in the myocardium and blood during hypoxic hypoxia]. | the citric cycle dehydrogenases and neutral peptide hydrolases (nph) activity was determined in the myocardium and blood serum of wistar rats under acute and prolonged hypoxic hypoxia. it was shown that the nph activity and the activity of the most oxidative enzymes change in the same direction during adaptation to the high-altitude conditions. the role of the nph in the oxidative metabolism reconstruction under acute and chronic hypoxia was discussed. | 1990 | 2238155 |
| antibiotic therapy for bacillus species infections. | we reviewed 36 cases of culture-proven bacillus species ocular infections occurring between september 1974 and december 1989. kirby-bauer disk sensitivities were available in 34 of the 36 cases (95%). all bacillus species isolates were sensitive to the aminoglycoside antibiotics (n = 34) and to vancomycin hydrochloride (n = 32); resistance to clindamycin was found in four of 18 (22%) of tested isolates. although b. cereus was uniformly sensitive to these antibiotics, resistance to clindamycin oc ... | 1990 | 2248335 |
| vibrios associated with red tides caused by mesodinium rubrum. | vibrios were isolated from red tides caused by mesodinium rubrum and also throughout the year in the ria de pontevedra, spain. the isolates were grouped into 14 phena by numerical toxonomy. strains associated with red tides were restricted to four phena: phena i and ii were vibrio alginolyticus, and phena iii and iv were vibrio tubiashii and vibrio anguillarum, respectively. v. anguillarum-like strains (phena v through xi) predominated throughout the year outside the red tide areas. cytotoxicity ... | 1990 | 2268167 |
| identification of type i iodothyronine 5'-deiodinase as a selenoenzyme. | a 27.8 kda membrane selenoprotein was previously identified in rat thyroid, liver and kidney, the tissues with the highest activities of type i iodothyronine 5'-deiodinase. this membrane enzyme catalyzes the deiodination of l-thyroxine to the biologically active thyroid hormone 3,3',5-triiodothyronine. a decrease in the activity of this enzyme, observed here in the liver of selenium-deficient rats, was found to be due to the absence of a selenium-dependent membrane-bound component. by chemical a ... | 1990 | 2268318 |
| characterization of activation and deactivation pathways of 4-(n-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (nnk) in rat hepatocytes. | we have characterized the metabolism of 4-(n-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (nnk) in cultured rat hepatocytes and have established the relationship between various metabolic pathways and single-strand breaks (ssb) in dna. metabolism of [5-3h]-nnk by carbonyl reduction, alpha-carbon hydroxylation and pyridine n-oxidation was linear from 0.5 to 6 h with 0.25-2 x 10(6) hepatocytes. using an alkaline elution assay, we observed that nnk induces ssb in dna in a dose- and time-dependent m ... | 1991 | 1855907 |
| corticotropin-releasing hormone is a rapid and potent convulsant in the infant rat. | corticotropin-releasing hormone (crh) administered into the cerebral ventricles of rats during the first postnatal week caused a specific and stereotyped behavior sequence: rhythmic chewing and licking (jaw myoclonus) were followed by 'limbic'-type seizures. the onset of the seizures was much more rapid (2-45 min vs 3-7 h) than in adult rats, and the convulsant doses were much lower (50 x 10(-12) mol per gram brain weight vs 750 x 10(-12) mol per gram brain weight in adults). crh potency in indu ... | 1991 | 1914160 |
| central nervous system involvement during infection by phlebovirus toscana of residents in natural foci in central italy (1977-1988). | central nervous system (cns) involvement was detected during infection caused by the sand fly-transmitted phlebovirus toscana. one hundred fifty-five cases of toscana virus-associated meningitis or meningoencephalitis were identified in a survey that lasted ten years, conducted in two regions of central italy. diagnosis was performed by different serologic tests. a combination of hemagglutination-inhibition and plaque-reduction neutralization or indirect immunofluorescence for igm, and enzyme-li ... | 1991 | 1951851 |
| epidermal cytokines and their roles in cutaneous wound healing. | cytokines are small proteins or glycoproteins which are synthesized and secreted by a variety of cell types. through binding to specific receptors on target cells, these hormone-like products regulate many normal cell activities, including growth and differentiation, migration and immune functions. within the epidermis, keratinocytes are the major source of cytokines along with melanocytes and langerhans cells. in response to a variety of injurious stimuli, including ultraviolet irradiation and ... | 1991 | 2064935 |
| the na+/glucose cotransporter (sglt1). | an important class of na+ transport proteins is the cotransporters. they exist in bacteria and animal cells and are responsible for the "active" accumulation of sugars, amino acids, carboxylic acids and some ions, e.g., i-, cl-, and po-4, in cells. in the small intestine and renal proximal tubule the cotransporters play an important role in the transport of salt and water across the epithelia. the most well known and best characterized na+ cotransporter is the intestinal brush border na+/glucose ... | 1992 | 1449065 |
| polyol pathway-mediated changes in cardiac muscle contractile properties: studies in streptozotocin-diabetic and galactose-fed rats. | contractile properties of left ventricular papillary muscles and atria from streptozotocin-diabetic and from non-diabetic rats fed a 40% galactose diet were measured in vitro. there was a characteristic slowing of twitch responses for both tissues and both treatments (p < 0.05). time to peak contraction was prolonged by 18-33% and maximum rate of contraction was reduced by 10-17%. relaxation was also affected, with a 13-37% increase in half-relaxation time and a 7-25% reduction in the maximum ra ... | 1992 | 1489541 |
| activation of solubilized g-proteins by muscarinic acetylcholine receptors. | binding of gtp and its analogue, guanosine 5'-o-[gamma-thio]triphosphate (gtp[s]) to g-proteins, and release of gtp[s] from g-proteins are stimulated by muscarinic acetylcholine (mach) receptors in intact cardiac membranes. upon solubilization of receptors and g-proteins by membrane extraction with the detergent, 3-[(cholamidopropyl)dimethylammonio]-1-propanesulphonate, followed by sucrose density gradient centrifugation, agonist-liganded mach receptors stimulated binding of gtp[s] and hydrolysi ... | 1992 | 1489667 |
| acupuncture analgesia. | acupuncture-produced surgical analgesia has been demonstrated in a wide variety of species under experimental and clinical circumstances. the main advantage is that no depressant drugs need to be used. the disadvantages of its use are unfamiliarity, the need for special equipment, inconsistent effects, and lack of restraint. | 1992 | 1533972 |
| diagnosis of sickle cell disease in chronically transfused patients. | standard electrophoretic methods for the diagnosis of hemoglobinopathies are confounded in individuals chronically transfused. we present the accurate diagnosis of sickle cell disease in two such transfused patients by the application of polymerase chain reaction technology to analyze patient's hemoglobin beta-chain genes directly. | 1992 | 1550267 |
| [relation between endocrinology and psychiatry. some recent developments]. | relations between endocrinology and psychiatry are developing in two main directions: behavioural effects of hormones. after the effects of peripheral hormones, recent works are concerned with a.c.t.h. and antidiuretic hormone (which interfere with memory process) and with hypothalamic peptides (which might have psychotropic properties, independant of their endocrine regulation function). -correlations between psychiatric syndroms and endocrine disorders. in some mentally depressed patients, dis ... | 2003 | 165466 |
| [can one make up for lack of humaneness?]. | 2003 | 187843 | |
| a simple, specific, radioisotopic assay for 5'-nucleotidase. | 2003 | 165748 | |
| the equilibrium constant and the reversibility of the reaction catalysed by nicotinamide-adenine dinucleotide kinase from pigeon liver. | the reversibility of the nad+ kinase reaction was established, and the kinetic parameters of the rate equation in the reverse direction were determined. the equilibrium constant of the reaction was determined by using the purified pigeon liver enzyme and radioactively labelled nicotinamide nucleotides. the relationship between kinetic parameters of the forward and reverse reactions is in reasonable agreement with the measured equilibrium constant. as expected from the proposed mechanism of actio ... | 2003 | 201249 |
| [uremic osteodystrophy. critical evaluation of the radiologic and humoral indices of bone resorption]. | 2003 | 262283 | |
| [normotensive pheochromocytoma]. | 2004 | 520932 | |
| familial dupuytren's contracture with predominantly female expression. | a family pedigree is described in which a strong dupuytren's trait is manifest predominantly on the female side. the genetic aspects of the condition are reviewed and the importance of gene penetrance is stressed. | 2004 | 444771 |
| [repair of huge hernia in scar]. | 2004 | 535813 | |
| [evaluation of the hemodynamics and the absorptive-excretory functions of the liver using radiopharmaceutical preparations]. | 2004 | 362109 | |
| fallacies of medially wedged heel for valgus foot. | 2004 | 521647 | |
| serum-cholesterol-binding reserve in patients with the nephrotic syndrome. | hyperlipidemia and premature atherosclerosis are known metabolic complications in patients with the nephrotic syndrome. in this study, we have measured serum levels of cholesterol, triglycerides and serum-cholesterol-binding reserve (scbr) in 22 patients (14 men, 8 women) with the nephrotic syndrome and in 21 hyperlipidemic men who served as control subjects. serum cholesterol levels were higher (p less than 0.005) in patients when compared to those of controls while triglyceride levels did not ... | 2004 | 492425 |
| [survey of late results of surgical treatment of atrial spetal defect (secundum type) (author's transl)]. | 2004 | 438563 | |
| case reports: cryptococcosis. | 2004 | 535192 | |
| arrest of alveolar multiplication in kyphoscoliosis. | a detailed morphometric study of the lungs of an adult patient with severe kyphoscoliosis of childhood onset is reported. the number of alveoli was less than the normal adult range and corresponded to the predicted values for a 12-month-old infant. this may have been a result of both premature cessation of alveolar multiplication as well as alveolar atrophy. the alveolar size was larger than normal suggesting that after cessation of alveolar multiplication further lung growth occurred by an exce ... | 2004 | 523187 |
| pathogenetic mechanisms in legionnaires' disease. | 2004 | 519205 | |
| [endocrinological diagnosis of pituitary neoplasms]. | 2004 | 438581 | |
| the construction of a membrane slide support for the observation of living cells. | the construction of a slide for examining living cells under the microscope under controlled conditions is described. | 2004 | 423235 |
| toward an effective system of ambulatory health care evaluation. | 2004 | 412153 | |
| [ige determination (rist, prist and others)]. | 2004 | 490927 | |
| [scheele research and acclaim in travels to other countries. the 250th birthday of carl wilhelm scheele]. | 2005 | 1287672 | |
| failure to consult specialist. | 2005 | 1173090 | |
| a volumetric assessment of pollen levels in the air of ann arbor, michigan. | 2005 | 1196148 | |
| task characteristics and a stage 6 sensorimotor problem. | a previously demonstrated high rate of failure on a stage 6 sensorimotor means-end problem, of children otherwise inferred to be in stage 6 development, prompted a study of task characteristics of the problem. a component part of the task was modified by introducing an additional visual cue; the purpose of the problem was unchanged. results indicated that problem solving was facilitated in the transformed condition, with older subjects performing somewhat better than younger subjects. the author ... | 2005 | 1183275 |
| effect of altitude relocations upon aado2 at rest and during exercise. | the supine pulmonary venous admixture (shunt) has been measured at cerro de pasco, 4,350 m altitude in eight subjects native to high altitude (han) under resting condition. alveolar-arterial o2 tension difference (aado2) was also determined at rest and during exercise. the same subjects were studied again after 10 days' sojourn at sea level in lima at 150 m altitude. they were compared with four subjects from sea level (sln) who were studied first at lima and after 2 and 10 days at cerro de pasc ... | 2005 | 1176413 |
| baillière tindall prizewinner .1. the clinical nurse consultant. | 2005 | 1129151 | |
| psoas abscess localization by gallium scan in aplastic anemia. | gallium 67 scanning is an effective method of detecting inflammatory lesions, especially abscesses. a 10-year-old boy with aplastic anemia and severe leukopenia and granulocytopenia had a psoas abscess diagnosed by gallium scan. the patient died with candida spesis 18 days after bone marrow transplantation. at autopsy, a chronic psoas abscess with candida was found. the gallium scan offers a clinically effective and noninvasive means of evaluating suspected infection in the granulocytopenic pati ... | 2005 | 1091749 |
| [in memory of jirŕ kruml, m.d., c.sc]. | 2005 | 1104202 | |
| trade-off between gestational age and miscarriage risk of prenatal testing: does it vary according to genetic risk? | it has been generally assumed that as genetic risk rises, so the higher procedure-related miscarriage rates of diagnostic tests done earlier in gestation become more acceptable. to test the hypothesis a decision tree was used, in which the only differences between two tests a and b were that a was carried out earlier in pregnancy and was more likely to cause miscarriage. over a wide range of rankings for the three outcomes (procedure-related miscarriage of a normal baby, early termination of pre ... | 2005 | 1978126 |
| [lumbosacral radiculography with dimer-x and amipaque. advantages, side effects and possible late complications]. | 2005 | 551604 | |
| the aching mouth and the aching psyche. | 2005 | 1074368 | |
| [pre- and postoperative radiotherapy of laryngeal cancer]. | 2005 | 1196026 | |
| child care in the people's republic of china--1973. part ii. | 2005 | 1168896 | |
| on the art of the abstract. | 2005 | 2756188 | |
| post-cannulation radial artery aneurysm--a rare complication. | the following case report describes an expanding aneurysmal dilatation of the radial artery which developed 17 days following cannulation. possible causes of this complication are: abnormal state of the vessel wall, multiple attempts at cannulation, and haematoma or infection at cannulation site. other major and minor sequelae following arterial cannulation are reviewed. | 2005 | 2253296 |
| case records of the massachusetts general hospital. weekly clinicopathological exercises. case 43-1975. | 2005 | 1178005 | |
| [primary breast cancer: conservation therapy]. | a series of 200 patients with primary breast cancer, treated with breast conservation between 1981 and 1988, was analyzed retrospectively. the mean age was 54 +/- 14 years and mean follow-up 36 months. 58 patients (29%) were in pathological stage i, 85 (42.5%) in ii a, 34 (17%) in ii b, and 7 (3.5%) in iii. 16 (8%) were in clinical stages i-ii; 40 (20%) had multifocal tumors and 40 intraductal components. 45% of the lesions were excised with good margins, 13.5% with close margins (0.5 cm), 9% wi ... | 2005 | 1317331 |
| midwifery and body fluid contamination. | 2006 | 1392970 | |
| [transient, prolonged, combined sicca syndrome of the eyes and mouth. occurrence along with a common cold in an 8-year-old girl]. | a girl of eight years fell ill with signs of common cold and bronchitis. already on the second day of illness, before any treatment was started, she showed symptoms of a sicca-syndrome, beginning in the eyes, later the mouth. ophthalmologic examination showed keratitis filiformis, histology of the salivary glands in the mucosa of the mouth was normal. local substitution therapy led to subjective improvement. the disorder of secretion persisted for four months only, then rapid restitutio ad integ ... | 2006 | 1435804 |
| schizophrenia: gender and familial risk. | the morbid risks for schizophrenia and any nonaffective psychosis in the first degree relatives of male and female schizophrenic probands were compared utilizing cox proportional hazards models. the schizophrenic probands (275 male; 106 female) were drawn from a larger sample of hospitalized patients obtained by systematically screening all psychiatric admissions to 15 facilities over a six-year period. proband diagnoses (dsm-iii) were based on a direct assessment of the patient and a review of ... | 2006 | 1560406 |
| what role will residency education take in the profession by the year 2000? | residency education has enjoyed relatively slow but steady growth since its inception in the mid-1970s. a certain segment of recent graduates consider graduation from optometry school as entry level and perceive the need for additional clinical education. the creation of new residency programs and the expansion of existing ones may occur in a variety of settings. for residency education to realize its full potential, optometry must seek federal support for post-graduate clinical education. this ... | 2006 | 1447463 |
| [local meeting series--a model for continuing education of the general practice staff]. | during the period january 1987 to june 1990 28 educational afternoon meetings were held for the office staff and nurses in general practice in bodø, as well as for the nurses in the bodø emergency clinic/service. office staff and nurses in the occupational health service were also invited, bringing the number up to 42. on average 40.0% of the invited persons attended the meetings. each meeting lasted 2 hours. the number attending the last meetings was so few that the series was discontinued. how ... | 2006 | 1557764 |
| non-beta-adrenergic-mediated peripheral circulatory hyperkinesia in hyperthyroidism. | systolic time intervals and brachial circulation, evaluated by pulsed doppler in terms of arterial diameter, blood velocity and flow, and vascular resistance, were studied in 12 hyperthyroid patients and in 12 normal controls. in patients, arterial circulation was studied before and during mechanical exclusion of the hand, and hemodynamic measurements were repeated after beta-blocker treatment and after obtainment of euthyroid state. compared with controls, patients had higher heart rate (p < 0. ... | 2006 | 1361313 |
| what's your assessment? scabies. | 2006 | 1482627 | |
| a double-blind trial of nocturnal supplemental oxygen for sleep desaturation in patients with chronic obstructive pulmonary disease and a daytime pao2 above 60 mm hg. | the efficacy of nasal oxygen during sleep was evaluated in patients with copd, episodic rapid eye movement sleep desaturation, and a daytime pao2 greater than 60 mm hg. the double-blind, randomized 3-yr trial used nasal oxygen versus room air in two groups of nocturnal sleep desaturating subjects. the setting was the outpatient chest clinic of a veterans affairs medical center. there were 51 patients with moderate to severe copd, daytime pao2 greater than or equal to 60 mm hg: 38 with proven rem ... | 2006 | 1586049 |
| [radiation protection in diagnostic radiology]. | for every diagnostical x-ray radiation exposure the applied dose has to be limited to the smallest possible value. within the scope of a general swiss survey it has been found that in the various medical practices and hospitals the applied doses varied quite strongly. the main reasons leading to an overdose were the operating conditions of the x-ray and film processing equipment, the film and foil materials and improper filming techniques. the applied single dose served as a measure for the radi ... | 2006 | 1636159 |
| uterine leiomyomas: cytogenetic and histologic profile. | the main purpose of this study was to determine whether there is any correlation between the cytogenetic abnormalities and histology in uterine leiomyomas. | 2006 | 1635734 |
| [a more hemodynamic surgery...]. | 2006 | 1594838 | |
| expression of her2/neu oncogene product p185 in correlation to clinicopathological and prognostic factors of gastric carcinoma. | the expression of the her2/neu gene product p185 was retrospectively analyzed in 58 patients with gastric carcinoma. the results were correlated to various clinicopathological and prognostic factors. positive membrane staining for p185 could be detected in 38% of the patients (22/58). membrane staining was significantly greater in well and moderately differentiated tumors of the intestinal type when compared with poorly differentiated lesions and carcinomas of the diffuse type (p less than 0.01) ... | 2006 | 1352299 |
| quantitative gamma-ray computed tomography of the radius in normal subjects and osteoporotic patients. | a new design of gamma-ray computed tomography (ct) scanner was used to measure bone density in 516 normal adults and in 116 female patients with osteoporotic fractures. trabecular bone density (tbd) was measured for a core of the ultradistal radius; cortical bone mass per unit length (mls) and mass per unit volume (mvs) were computed for the radius shaft. tbd, mls and mvs peaked at the age of about 40 in females and fell by 32%, 15% and 24%, respectively, by the age of 65. in males, tbd decrease ... | 2006 | 2242474 |
| effects of norethisterone on pressor response to angiotensin ii in men. | we examined the effects of norethisterone and/or mestranol on the pressor response to angiotensin ii in 20 healthy men. | 2006 | 1635747 |
| thymocytopoiesis is maintained by blood-borne precursors throughout postnatal life. a study in parabiotic mice. | this study was designed to resolve the long standing controversy as to whether hematogenous precursors or resident intrathymic precursors maintain thymocytopoiesis in postnatal life. the kinetics of thymic chimerism was examined over a 21-wk period in 105 pairs of nonirradiated, thy-1-alloantigen-disparate, parabiotic b10.s mice. thymic chimerism reached reached maximum levels of 25% in the thy-1b and 16% in the thy-1a partners (mean 20.5% and 9.8%, respectively) 6 to 7 wk after parabiotic union ... | 2006 | 1347301 |
| design and inhibitory properties of synthetic bowman-birk loops. | a cyclic tridecapeptide based on the sequence of an anti-tryptic loop of a bowman-birk inhibitor was synthesized, and demonstrated to be active as an inhibitor of trypsin. molecular modeling of this sequence suggested an improved sequence which demonstrated an order of magnitude improvement in the inhibitory constant. | 2006 | 1446974 |
| [conservative therapy of ulcerative colitis and crohn disease]. | basis treatment of severe ulcerative colitis and crohn's disease comprises the systemic administration of corticosteroids. if the conditions are less severe, treatment with oral sulfasalazine or 5-aminosalicylic acid (5-asa) can be attempted. distal ulcerative colitis may respond to topical corticosteroids of enemas with sulfasalazine or 5-asa. in long-term treatment with high-dose corticosteroids, azathioprine and 6-mercaptopurine may be employed to reduce the corticosteroid requirement. there ... | 2006 | 1855750 |
| [conservative celioscopic treatment of isthmic ectopic pregnancies]. | twenty-six ectopic pregnancies located strictly within the isthmus were treated surgically using conservative laparoscopic techniques. in each and every case the triton's monopolar electrode was used to perform salpingostomy which was followed by the aspiration of the trophoblast. this therapeutic approach is very reliable since only one failure was observed (3.9%), requiring a further operation during which salpingectomy was carried out by laparoscopy. it was possible to evaluate subsequent fer ... | 2006 | 1838757 |
| the carpal tunnel syndrome: part ii. | the carpal tunnel syndrome is a compression of the median nerve within the carpal tunnel with very specific signs and symptoms. anatomical dissection of 156 wrists is presented and then the authors compare their findings with the findings of other investigators. the purpose of this article is not to present results but rather to discuss the anatomic entities involved with the syndrome and to present the open treatment modality. | 2006 | 1550309 |
| carbohydrate specificity of the receptor sites of mistletoe toxic lectin-i. | the carbohydrate specificity of mistletoe toxic lectin-i (ml-i) was studied by haemagglutination-inhibition assay. the results indicated that ml-i has a broad range of affinity for gal alpha,beta linked sequences. the galabiose (e, gal alpha 1----4gal) sequence, a receptor of the uropathogenic e. coli ligand, was one of the best disaccharide inhibitors tested. the lectin also exhibits affinity for lac(gal beta 1----4glc), t(gal beta 1----3galnac), i/ii(gal beta 1----3/4glcnac) and b(gal alpha 1- ... | 2006 | 1525184 |
| ga-67 citrate scan in vascular graft infection. | the clinical utility of the ga-67 scan has been studied in 9 patients with clinical suspicion of vascular graft infection. eleven grafts were analyzed: 4 aortobifemoral, 2 iliofemoral, 3 femoropopliteal, 1 axillofemoral, and 1 axillobifemoral. the ga-67 scan was positive in 8 grafts with bacteriological proof of infection and negative in 3 grafts in which infection was ruled out by clinical follow-up. a ga-67 scan also demonstrated the spread of infection to the thigh in two patients and to the ... | 2006 | 1489633 |
| [clinico-morphological signs of different forms of destructive pancreatitis]. | clinicomorphological comparisons in 434 cases of destructive pancreatitis showed that macroscopic signs of destruction develop in the first 12 hours from the onset of the attack. the elaborated criteria make it possible to evaluate the main morphological components of destructive pancreatitis--pancreonecrosis proper, parapancreatitis, peritonitis, and "polyvisceritis" and to use therapeutic measures on an individual basis. | 2006 | 1779556 |
| a comparative study for fiberoptic and video endoscopic determination of the extent in minimal changes of gastric mucosa using indigo dye spraying. | the image resolution of fiberoptic and video endoscopy was compared in a series of patients with early gastric cancer. eighteen patients were divided into two groups. one group of patients (n = 9) was evaluated with fiberoptic endoscopy while the second group (n = 9) was evaluated using video endoscopy. the extent of cancer invasion, with special attention to size, shape and type of the lesions, was evaluated in each patient. attempts were also made to identify the proximal and distal limits of ... | 2007 | 2374986 |
| [secretory gm3 sialidase during the cell growth]. | 2007 | 2258655 | |
| [treatment of occlusive diseases of blood vessels of the lower extremities at a specialized unit of the polyclinic]. | organization of specialized angiological rooms with the day hospital in the polyclinic makes treatment of patients with obliterating diseases of peripheral vessels more effective. complex approach to treatment, the dynamic observation of the patients shorten the time of the coming of remission. | 2007 | 2175518 |
| the first 2 years of the gambian national cancer registry. | we describe the creation, and the first 2 years experience, of the gambian national cancer registry. the major problems involved in the creation of such a registry in a developing country are discussed. the data accumulated show a low overall rate of cancer incidence compared to more developed parts of the world and indicate that the prevalent cancers, hepatoma, carcinoma of the cervix and lymphoma, are likely to be due to infectious agents. it is hoped that immunisation of children under one ye ... | 2007 | 2223583 |
| the first 2 years of the gambian national cancer registry. | we describe the creation, and the first 2 years experience, of the gambian national cancer registry. the major problems involved in the creation of such a registry in a developing country are discussed. the data accumulated show a low overall rate of cancer incidence compared to more developed parts of the world and indicate that the prevalent cancers, hepatoma, carcinoma of the cervix and lymphoma, are likely to be due to infectious agents. it is hoped that immunisation of children under one ye ... | 2007 | 2223583 |
| predominant expression of lambda light chain in adult cases with non-t-cell acute lymphocytic and chronic myelogenous leukemia in lymphoid blast crisis. | the authors investigated cytoplasmic immunoglobulins of the leukemic cells from 20 adult cases with non-t-cell acute lymphocytic leukemia (all) and from three cases with chronic myelogenous leukemia in lymphoid blast crisis using immunoelectron microscopy. they also studied these cases using various monoclonal antibodies. of the 23 examined cases, nine were negative for both heavy and light chains of immunoglobulins; the authors defined these as common all. two cases were positive for the mu cha ... | 2007 | 1906773 |