Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| [testicular damage in elastorrhexis generalisata]. | 2016 | 5031134 | |
| clinical pathological conference: a case of lupus nephritis from temple. | 2016 | 4810608 | |
| [1969 review on contact lenses]. | 2016 | 4926494 | |
| are daughter cells equivalent? | 2016 | 4863325 | |
| genitourinary tract involvement with systemic mycosis. | 2016 | 5033965 | |
| [responsability of physicians and surgeons]. | 2015 | 4679102 | |
| [responsability of physicians and surgeons]. | 2015 | 4679102 | |
| [a study on the effect of cadmium chloride on the mineral metabolism in bone callus (author's transl)]. | 2015 | 4523946 | |
| [criteria for work capacity following occupational eczemas]. | 2015 | 4393433 | |
| editorial: bicentennial year: prelude. | 2015 | 4586427 | |
| [cryptorchism. delayed results of the surgical treatment]. | 2015 | 4390889 | |
| an improved method for the preparation of adnamine. | 2015 | 4390843 | |
| the nature and site of action of the ir-1 gene. | 2015 | 4549288 | |
| electrocardiography. snapshot diagnosis. | 2015 | 4413203 | |
| acute leukemia presenting as jaundice with acute liver failure. | 2015 | 4593955 | |
| data collection in the home health agencies of rhode island--home health agency management system brief. | 2015 | 4496466 | |
| ly-4, a new locus determining a lymphocyte cell-surface alloantigen in mice. | a new locus is described that determines an alloantigen on the surface of lymphocytes. it differs from loci previously described in that the corresponding antibody, at least in most antisera, reacts almost exclusively with node lymphocytes, and weakly or not at all with thymuslymphocytes. positive strains include c57bl/6, c57bl/10, c57l, c57br/cd, and rf; negative strains include balb/c, c3h, and sjl. the symbol ly-4 is assigned, with the c57bl/6 allele being ly-4(b), and the balb/c allele ly-4( ... | 2015 | 4515607 |
| description of a food recording electronic device for use in dietary surveys. | a food recording electronic device has been developed for quantitative collection of dietary data in the home for a period of up to 3 weeks. the accumulated information on the weights and types of food, and time of consumption, is transferred to a host computer for calculation of the nutrient composition of the diet. using this method the subject does not have to read the balance or keep a written diary, and the need for coding of records by a dietitian is eliminated. | 2014 | 3957699 |
| mechanisms of lipid peroxidation. | this article provides an overview of how peroxidation of unsaturated lipids takes place and how it can be measured. several different aspects of free-radical-mediated lipid peroxidation are discussed, including: the catalytic role of chelated iron and other redox metal ions; induction by reducing agents such as superoxide, ascorbate, and xenobiotic free radicals; suppression by antioxidant chemicals and enzymes; and how peroxidation that depends on pre-existing hydroperoxides (lipid hydroperoxid ... | 2014 | 3915303 |
| amantadine in parkinson's disease. | 2014 | 4189764 | |
| dyshormonogenetic goitre with high circulating levels of thyroid-stimulating hormone. | 2014 | 4101504 | |
| magnetic resonance imaging in head injured patients with normal late computed tomography scans. | in 11 patients who had undergone blunt head injuries, computed tomography (ct) scans of the brain performed 4-24 months posttrauma were normal. the patients showed a variety of cognitive and behavioral disturbances. magnetic resonance imaging (mri) studies revealed abnormalities that were mainly confined to the frontal and temporal lobes. magnetic resonance imaging revealed signals of increased intensity compatible with old contusions, loss of discrimination between gray and white matter, and ir ... | 2013 | 3824139 |
| exaggerated epinephrine responses to hypoglycemia in normal and insulin-dependent diabetic children. | to determine whether children with insulin-dependent diabetes mellitus (iddm) might have exaggerated hormonal responses to hypoglycemia, the euglycemic-hypoglycemic glucose clamp procedure was used to provide a uniform hypoglycemic stimulus (plasma glucose kept at 90 mg/dl for 2 hours, then reduced to 50 to 55 mg/dl for 1 hour) in children and adults with and without iddm. the chidren with iddm showed an exaggerated rise in plasma epinephrine levels (625 +/- 112 pg/ml) compared with adults with ... | 2013 | 3585599 |
| exaggerated epinephrine responses to hypoglycemia in normal and insulin-dependent diabetic children. | to determine whether children with insulin-dependent diabetes mellitus (iddm) might have exaggerated hormonal responses to hypoglycemia, the euglycemic-hypoglycemic glucose clamp procedure was used to provide a uniform hypoglycemic stimulus (plasma glucose kept at 90 mg/dl for 2 hours, then reduced to 50 to 55 mg/dl for 1 hour) in children and adults with and without iddm. the chidren with iddm showed an exaggerated rise in plasma epinephrine levels (625 +/- 112 pg/ml) compared with adults with ... | 2013 | 3585599 |
| the ninety-nine day kaiser. | 2013 | 3549136 | |
| [impaired response to adrenal suppression tests in epileptic patients in treatment with carbamazepine]. | 2013 | 3561370 | |
| social factors and professional attitudes as determinants of the frequency of small surgical procedures among children in greece. | data concerning histories of adenoidectomy (ad), tonsillectomy (t) and appendectomy (ap) were collected from the escorts (mainly mothers) of 2296 children 3-12 years-old. the children were admitted as outpatients at the first department of paediatrics of the university of athens or the polyclinic of the children's welfare center of pikpa in pireaus, during the last six months of 1983. among children with median age of about six years, 12 percent had already had at least one operation (ad, t or a ... | 2013 | 3811607 |
| [anesthesia in aortocoronary bypass surgery: comparison of effects on hemodynamics of recent technics of total intravenous anesthesia]. | 20 patients electively scheduled for operation were enrolled in the study and anaesthetized randomly with one of the two techniques etomidate + fentanyl (i) or flunitrazepam + fentanyl (ii). haemodynamics were assessed by continuously measuring blood pressure in the systemic and pulmonary circulations, as well as the heart rate, and intermittently determining the cardiac output. it could be shown that systemic arterial blood pressure, in spite of an initial drop after induction of anaesthesia, r ... | 2013 | 3907396 |
| a clinical approach to pacemaker identification and follow-up. | 2013 | 3568600 | |
| thanatophoric dwarfism: a parent's point of view. | 2013 | 3996686 | |
| thanatophoric dwarfism: a parent's point of view. | 2013 | 3996686 | |
| biodegradable microspheres. x: some properties of polyacryl starch microparticles prepared from acrylic acid-esterified starch. | acrylic acid-esterified starch was produced by reacting starch with acrylic acid chloride. this reaction was rapid and easy to control. introduction of acrylic groups into starch reduced the enzymatic degradability of starch (e.g., with 12 acrylic groups/100 glucose residues, approximately 75% of the degradation products eluted before glucose on gel filtration). the degradability could be increased to a large extent by preincubation at ph 5.5 in vitro (e.g., after 16 weeks, the corresponding fig ... | 2012 | 3440940 |
| clinical and histological evaluation of gingival massage in the treatment of chronic gingivitis. | 2012 | 4161925 | |
| multiple pterygium syndrome. an overview. | the longitudinal course of two sisters with multiple pterygium syndrome is reported. the findings in these siblings are compared with those of 27 children described in the medical literature. the longitudinal course of short stature, scoliosis, talipes equinovarus, pterygia, hearing loss, and pubertal and intellectual development in this syndrome is described. recommendations are made for a multidisciplinary approach to individuals with multiple pterygium syndrome, which includes the services of ... | 2012 | 3289375 |
| estimation of missing cone data in three-dimensional electron microscopy. | the range of tilt angles for which projected images of two-dimensionally periodic specimens can be obtained in electron microscopy is limited both by technical aspects, such as goniometer design, and by the more fundamental limitation of object thickness. the lack of a full set of projections causes a missing cone in the reciprocal space data for the object, which will give an anisotropic resolution in a three-dimensional reconstruction and may cause the quality to be impaired by spurious featur ... | 2011 | 3244969 |
| effects of azelastine on allergen- and exercise-induced asthma. | the effects of the new anti-allergic drug, azelastine, on allergen- and exercise-induced asthma were studied. in six allergen inhalation tests for five asymptomatic asthmatic patients, the maximum percentage fall in fev1.0 immediately after inhalation of allergen extract was 37.2 +/- 6.4 per cent (mean +/- sem). as compared with a placebo, the maximum percentage fall in fev1.0 with azelastine after inhalation of allergen extract in the same manner as with the placebo was 17.3 +/- 6.9 per cent. t ... | 2011 | 3907651 |
| effects of azelastine on allergen- and exercise-induced asthma. | the effects of the new anti-allergic drug, azelastine, on allergen- and exercise-induced asthma were studied. in six allergen inhalation tests for five asymptomatic asthmatic patients, the maximum percentage fall in fev1.0 immediately after inhalation of allergen extract was 37.2 +/- 6.4 per cent (mean +/- sem). as compared with a placebo, the maximum percentage fall in fev1.0 with azelastine after inhalation of allergen extract in the same manner as with the placebo was 17.3 +/- 6.9 per cent. t ... | 2011 | 3907651 |
| thyroid function in affective disorders and alcoholism. | the psychoneuroendocrinology of mood disorders and alcoholism is reviewed here. for reasons of both space and clarity, the article focuses on the clinical data and largely omits the basic science data. | 2011 | 3132602 |
| the long-term psychiatric consequences of accidental injury. a longitudinal study of 107 adults. | one hundred and seven accidentally injured adults were studied while in hospital and assessed prospectively twice more in a mean period of 28 months. the patients were studied by means of taped clinical interviews, including the comprehensive psychopathological rating scale (which includes the montgomery-asberg depression rating scale), and several self-report measures of distress (schedule of recent life events, general health questionnaire, impact of event scale and state anxiety inventory) at ... | 2011 | 3256381 |
| [isotope angiocardiographic study of 30 cases of ventricular tachycardia with fourier phase analysis]. | twenty-seven patients (15 men, 12 women; mean age 48.9 years) suffering from ventricular tachycardia (vt) (n = 30) were studied by radionuclide angiocardiography with fourier phase analysis, both in sinus rhythm and during tachycardia. vt was spontaneous, electrically inducible, sustained, haemodynamically stable and monomorphous, with a mean rate of 174 beats/min (range: 115-260 beats). heart diseases responsible for vt were: non-obstructive cardiomyopathy (n = 7), hypertrophic cardiomyopathy ( ... | 2011 | 3136707 |
| [varicosities as a result of acquired non-traumatic arteriovenous fistulas]. | 82 patients with telangiectasias of the lower extremities near the knee were examined. at the level of these telangiectasias, it was possible to hear, with the doppler, an arterial pulse and the histological examination showed that the telangiectasias were secondary to an arterio-venous fistula. since this shunt is not an important one, we feel that this is a micro-fistula. in most cases, telangiectasias appear at puberty or during delivery in young women. the clinical picture is not univocal an ... | 2010 | 2953037 |
| [relation between glycolysis and na+/h+-antiport in ascites tumor cells]. | 2010 | 2872024 | |
| [thrombocyte function in vitro in storage over 5 days]. | 2010 | 2944509 | |
| 1989 lasker awards salute physician-author, four cell biologists, french endocrinologist. | 2009 | 2674483 | |
| [factors in therapeutic decisions]. | 2009 | 2652061 | |
| [the role of the trs-glucotest apparatus in self-monitoring by patients with diabetes mellitus]. | successful treatment of diabetes mellitus requires a reliable control of glycaemia where self-monitoring with reflectometer plays a significant role. trs-glucotest reflectometer (trs, zagreb), the result of our experts' efforts, makes it possible for diabetic patients to perform self-monitoring. according to our research trs-glucotest reflectometer shows lower blood glucose levels for more than 20%, especially in 3.8-11.5 mmol/l range of glucose concentration, that is in the range most often exp ... | 2009 | 2633013 |
| [analysis of the effectiveness of treating severe cases of sciatica of radicular origin by intrathecal administration of depo-medrol]. | 2009 | 2669351 | |
| [the risk of suicide in cancer patients derived from a cancer registry]. | the incidence of suicide among cancer patients has been examined in several previous epidemiological studies, which have suggested an increased risk especially in the period following diagnosis. the role of factors which may modulate the risk, such as individual patient characteristics or that of cancer (site, prognosis or type of treatment), have not been systematically studied and available results are often contradictory. in geneva, the existence of a tumor registry, which follows patients co ... | 2008 | 2374843 |
| elimination of ciprofloxacin and three major metabolites and consequences of reduced renal function. | the pharmacokinetics and elimination of ciprofloxacin and its three major metabolites desethylene ciprofloxacin (m1), sulfonylciprofloxacin (m2), and oxociprofloxacin (m3) were determined in 18 volunteers with normal and varying degrees of reduced renal functions. one dose of 500 mg ciprofloxacin was given orally. samples were assayed by high-pressure liquid chromatography. serum concentrations of both ciprofloxacin and its metabolites were only slightly influenced by the renal function. the ser ... | 2008 | 2612228 |
| weight gain associated with psychotropic drugs. | the weight increase that is an often reported side effect of psychotropic drug use has implications for health risks as well as medication noncompliance. in this article i review the literature on the association between the use of several classes of psychotropic drugs and weight gain, discuss the possible mechanisms for this effect, and offer some practical approaches for reducing the risk of drug-induced weight gain, including the identification of a group of patients "at risk." | 2008 | 2566204 |
| introduction to endoscopic therapy for bleeding peptic ulcers. | 2007 | 2242806 | |
| [prognosis of silent myocardial ischemia and its strategy for treatment]. | 2007 | 2258668 | |
| the nature and causes of hippocampal long-term potentiation. | one of the most fascinating features of the hippocampus is its capacity for plasticity. long-term potentiation (ltp), a stable facilitation of synaptic potentials after high-frequency synaptic activity, is very prominent in hippocampus and is a leading candidate memory storage mechanism. here, we discuss the nature and causes of ltp and relate them to endogenous rhythmic neuronal activity patterns and their potential roles in memory. anatomical studies indicate that ltp is accompanied by postsyn ... | 2007 | 2168058 |
| stress amongst teachers of children with mental handicaps. | 2006 | 1428389 | |
| when intravesical measures fail. indications for cystectomy in superficial disease. | the indications for intravesical therapy for superficial bladder cancer include multifocal or recurrent tumors, lamina propria invasion, cis, and superficial involvement of the prostatic urethra. tumor-free success rates approach 70% in most series. intravesical therapy is usually administered as a 6-week course with a re-evaluation of the bladder at the 3-month interval. if disease persists, a second 6-week course of therapy is administered. if tumor recurs or persists at the 6-month evaluation ... | 2006 | 1636242 |
| origin of the right vertebral artery from the left side of the aortic arch proximal to the origin of the left subclavian artery. | 2006 | 1595475 | |
| aging and immunity. | the function of the immune system peaks at around puberty and gradually declines thereafter with advance in age. the age-related decline of immunological function primarily occurs in the t cell-dependent immune system and is generally associated with increase in susceptibility to infections as well as in incidence of autoimmune phenomena in the elderly. the age-related change in t cell-dependent immune functions can be ascribed to the physiological thymic atrophy which starts in an early stage o ... | 2006 | 1449050 |
| [antibodies to neutrophilic granulocytes (p-anca): a further indication for a common origin of ulcerative colitis and primary sclerosing cholangitis?]. | 2006 | 1636280 | |
| [disturbance of glucose metabolism in dialysis patients--analysis of three studies of ivgtt in dialysis patients during 25 years]. | 2006 | 1578733 | |
| identification and characterization of deoxyguanosine-crotonaldehyde adducts. formation of 7,8 cyclic adducts and 1,n2,7,8 bis-cyclic adducts. | crotonaldehyde, a chemically reactive alpha,beta-unsaturated carbonyl compound, is an important industrial chemical and a ubiquitous environmental pollutant. it has been shown to be carcinogenic and mutagenic. we have studied the reaction of crotonaldehyde with nucleosides and 5'-mononucleotides and found three different types of adducts with deoxyguanosine and 2'-deoxyguanosine 5'-monophosphate. no adducts could be isolated either with nucleosides other than deoxyguanosine or with nucleotides o ... | 2006 | 1489932 |
| amalgam--fact and fiction. | a brief history of amalgam is given, stressing the role of g. v. black. the background and the progress of the two amalgam wars are sketched. aspects are presented of the drawbacks of amalgam with respect to toxic effects of, especially, mercury vapor and corrosion products. an account is given of some frequent fallacies concerning the health hazards of dental amalgam fillings and the role of psychosocial factors in the development of illness attributed to amalgam is emphasized. | 2006 | 1557606 |
| symptomatic and silent myocardial ischaemia in hypertensive patients with left ventricular hypertrophy. | to assess the prevalence of symptomatic and silent myocardial ischaemia in patients with hypertensive left ventricular hypertrophy. | 2005 | 1389717 |
| arrest of alveolar multiplication in kyphoscoliosis. | a detailed morphometric study of the lungs of an adult patient with severe kyphoscoliosis of childhood onset is reported. the number of alveoli was less than the normal adult range and corresponded to the predicted values for a 12-month-old infant. this may have been a result of both premature cessation of alveolar multiplication as well as alveolar atrophy. the alveolar size was larger than normal suggesting that after cessation of alveolar multiplication further lung growth occurred by an exce ... | 2004 | 523187 |
| creatine-kinase and ck-mb isoenzyme activity in serum of patients after surgical operations, polytrauma and other damage to skeletal muscle. | 2004 | 535155 | |
| [aplastic anemia treated by isogeneic or allogeneic bone marrow transplantation (author's transl)]. | 2004 | 368376 | |
| [lászló blaskovics]. | 2004 | 355973 | |
| [a comparison of diffusion and photometric method in determining the level of lysozyme in clinical practice (author's transl)]. | 2002 | 134836 | |
| [microclimate of soligorsk potassium mines and its effect on the well-being and work capacity of miners]. | 2002 | 123877 | |
| hl-a antigens in idiopathic addison's disease. | the frequencies of 36 hl-a antigens of the sd-1, sd-2 and sd-3 locus have been determined in 20 patients with idiopathic addison's disease and compared with those of 450 controls. no significantly different hl-a antigen frequencies could be observed in both groups. these findings are in contradiction to data reported by a copenhagen group. possible mechanisms which might have led to this discrepancy are discussed. | 2002 | 126574 |
| [peculiarities in the development of 2 cases of acute otomastoiditis]. | 2002 | 135309 | |
| [determination of hva and 5-hiaa in epileptic syndromes in basal conditions and after treatment with probenecid]. | 2001 | 95499 | |
| soluble and particulate glycolysis in developing castor bean endosperm. | 2001 | 125088 | |
| [short-term effects of gamma-globulins on sleep organization in epileptic patients (author's transl)]. | a study of the effect of gamma-globulins on sleep was conducted in 8 patients aged 1 to 35 years with epilepsy not responding to any of the conventional treatments. two polygraphic recordings were carried out during the 4th and 5th nights following a placebo injection and then an injection of gamma-globulin 16 merieux (1 ml/kg). the short-term effects of the gamma-globulins were : --reduction in percentage of paroxysms, --an acceleration in the electroencephalographic tracings of the different s ... | 2001 | 93297 |
| analysis of cellular dna distributions. i. g2/g1 channel ratios. | in the influencent-flow cytophotometric measurement of cellular dna content the dna distributions usually have two peaks. the second peak, which corresponds to the 4c dna content of g2 and m cells, is often positioned at lower values of dna content than twice that of the 2c dna peak which contains g1 cells. computerized numerical analyses were performed on artificial dna distributions in which the proportion of s-phase cells was varied. it was demonstrated that the contribution of late s-phase c ... | 2001 | 95178 |
| [tumor plasminogen activators and their clinical significance]. | by means of a radio-immunological method the amount of plasminogen activators released by tumours was determined. the concentrations of tumour plasminogen activators was considerably higher in the venous blood of ovarial tumours than in the peripheral blood. in the uterine fluid the uterus cavity the concentration of plasminogen activator was increased in cases with neoplastic endometrium compared to those with normal endometrium. | 2001 | 94895 |
| primary intracranial yolk sac tumor: immunofluorescent demonstration of alpha-fetoprotein synthesis. | an autopsy case of 20-year-old male with primary intracranial yolk sac tumor (endodermal sinus tumor) is reported. whereas the biopsy specimen obtained from the pineal region showed diffuse proliferation of atypical tumor cells, the metastatic subdural tumor removed from lumbar spinal region had the characteristic histologic appearance of yolk sac tumor. the histologic diagnosis was intracranial yolk sac tumor originating in the pineal gland. the elevated amount of alpha-fetoprotein in the cereb ... | 2001 | 56986 |
| intrathymic injection of antigen: a potent procedure for the induction of suppressor t cells. | immunological tolerance is induced in mice by intrathymic injection of hsa. the tolerance thus induced is mediated by suppressor t cells. strong tolerance persists more than 56 days after the induction, and the high efficiency of the tolerance thus induced is accounted for in terms of the number or the potentiality of suppressor cells. possible mechanisms of suppressor t cell induction by it injection of the antigen are discussed briefly. | 2001 | 92509 |
| neurolytic lumbar sympathetic blockade: duration of denervation and relief of rest pain. | 2000 | 92205 | |
| the periodic schiff-methenamine (pasm) staining of renal biopsies--a light electron microscopic study. | 2000 | 58851 | |
| effects of probucol on hyperlipidemic patients with cardiac allografts. | probucol, a well-tolerated new drug with moderate hypocholesterolemic effect in the general population, was evaluated in hypercholesterolemic (greater than 300 mg/dl) cardiac transplant recipients. nine patients received probucol, 500 mg twice daily, in a single-blind, placebo-controlled trial lasting 20 weeks. six patients responded with cholesterol falls of -20% (mean, -13.2%), and 1 patient showed minimal change. one patient developed cardiac rejection and was excluded, and another responded ... | 2000 | 94402 |
| morphometric analyses of the electric organ of torpedo: the influence of different fixative modes on the vesicle diameter. | the influences of various fixatives on the vesicle size of the electric organ of torpedo marmorate were investigated. thin section and freeze etched preparations were examined under the electron microscope. in thin section increased vesicle diameters were observed compared with the freeze etched preparations. the same experiments in different torpedo fish led to significantly different vesicle sizes observed. variations of the molarity, the ph and osmolarities result in particularly high differe ... | 1999 | 32156 |
| intergenic complementation after fusion of fibroblasts from different patients with beta-galactosidase deficiency. | 1999 | 103586 | |
| the effect of mazindol on metabolic and regulatory changes in obese women during weight reduction. | the effect of mazindol (1 mg/day) on some metabolic and regulatory values was investigated in ten adult obese women and compared with the same number of controls during weight reduction in hospital (a five-times repeated cycle of 5 days complete starvation and 3 days on a 500 kcal(2.1mj/day diet.) mazindol caused a rise of hydroxyacyl coa dehydrogenase in striated muscle by 70 per cent and a marked decline in malic dehydrogenase. mazindol also produced higher levels of non-esterified fatty acids ... | 1999 | 93588 |
| [prevention of coronary heart disease. suitability of ambulatory coronary groups]. | 1998 | 107406 | |
| pseudoaneurysm of the dorsalis pedis artery secondary to nonpenetrating trauma. | 1998 | 35018 | |
| lack of experimental evidence for frequency-dependent selection at the alcohol dehydrogenase locus in drosophila melanogaster. | two experiments were conducted for testing frequency-dependent selection at the alcohol dehydrogenase locus (adh; map position, 2--50.1), where two types of alleles, adhf and adhs, have been found to be polymorphic in natural populations. first, a competition experiment was carried out between inversion-free adhf/adhf and adhs/adhs genotypes at five gene frequency levels (those of adhf = 0.83, 0.67, 0.5, 0.33, and 0.17). first-instar larvae of the two homozygous types in various ratios were plac ... | 1998 | 106396 |
| the effects of primary elevation of cerebral venous pressure on cerebral hemodynamics and intracranial pressure. | 1998 | 106185 | |
| examination of the local lymph node assay for use in contact sensitization risk assessment. | the purpose of this study was to evaluate the utility of the murine local lymph node assay (llna) for contact sensitization risk assessment. cellular proliferative activity in draining lymph nodes was determined for individual animals on day 5 following four daily epicutaneous applications of the test chemical to the ears. seventeen chemicals were tested, covering a range of materials including preservatives, drug actives, and perfume raw materials. the assay was found to be useful for identifyi ... | 1992 | 1459374 |
| rapid pcr-cloning of full-length mouse immunoglobulin variable regions. | 1991 | 1367218 | |
| cardiomyopathy and woolly haircoat syndrome of hereford cattle. | 1991 | 2043089 | |
| [intrauterine mycoplasmosis in premature infants]. | 1990 | 2075070 | |
| purification and complex formation analysis of a cysteine proteinase inhibitor (cystatin) from seeds of wisteria floribunda. | seeds of wisteria floribunda contain several kinds of cysteine proteinase inhibitor (cystatin). we purified and characterized one of these inhibitors, named wcpi-3. the molecular weight of wcpi-3 was estimated to be 17,500 and 15,700 by gel filtration and sds-page, respectively. the isoelectric point was 5.7. wcpi-3 formed an equimolar complex with native papain and the dissociation constant was estimated to be 6.1 nm. complex formation between wcpi-3 and cys25-modified papain, such as s-carboxy ... | 1990 | 2292589 |
| peptide regulation of adrenal medullary function. | the discovery of peptides in the splanchnic nerve and adrenal gland, and their co-existence with conventional neurotransmitters raises questions about their possible functional roles in catecholamine (ca) secretion and gene transcription in the adrenal gland. short-term, stress-induced ca secretion is regulated biphasically by substance p (sp) which inhibits acetylcholine (ach) action at sp greater than 10(-6) m and facilitates ca secretion in response to metabolic and physical stressors, ach or ... | 1990 | 1694230 |
| the renal response to an acute protein load in man: clinical perspective. | 1990 | 2109280 | |
| retinoid-binding proteins in human oral mucosa. | vitamin a affects epithelial differentiation and growth via at least 3 different binding proteins. the specific delivery of extracellular retinol to target cells is performed by plasma retinol-binding protein (rbp) while cellular retinol- and retinoic acid-binding proteins (crbp and crabp) are implicated in the cellular action of the 2 natural retinoids. we have studied the levels of these 3 binding proteins by gel filtration and polyacrylamide electrophoresis in human oral mucosa, epithelium an ... | 1988 | 2840487 |
| metabolism of hexachloro-1,3-butadiene in mice: in vivo and in vitro evidence for activation by glutathione conjugation. | 1. the metabolism of 14c-hexachloro-1,3-butadiene (hcbd) was studied in mice and in subcellular fractions from mouse liver and kidney. 2. in the presence of glutathione (gsh), liver microsomes and cytosol transformed hcbd to s-(pentachlorobutadienyl)glutathione (pcbg). pcbg formation in subcellular fractions from mouse kidney was very limited. oxidative metabolism of hcbd by cytochrome p-450 could not be demonstrated. 3. cysteine conjugate beta-lyase was present in mitochondria and cytosol from ... | 1988 | 3176519 |
| specific neuro-radiological diagnosis of herpes encephalitis in an animal model. | the potential of utilizing a radio-labelled derivative of the antiviral drug (e)-5-(2-iodovinyl)-2'-deoxyuridine (ivdu) for the specific, non-invasive, in vivo diagnosis of herpes simplex virus encephalitis (hsve) was investigated in a rat model of the disease. following pharmacological disruption of the blood brain barrier radiolabelled ivdu was administered by intra-carotid injection. brain radioactivity was compared between control and infected animals via gamma camera scintigraphy. after cle ... | 1988 | 3415476 |
| site-specific endonucleolytic cleavages and the regulation of stability of e. coli ompa mrna. | the stability of ompa mrna is growth-rate dependent. we show that the 5' noncoding region of this mrna provides a target for site-specific endonucleases. the rate of degradation of ompa mrna parallels the rate of these endonucleolytic cleavages, implying that endonucleolytic rather than exonucleolytic attack is the initial step in ompa mrna degradation. thus the 5' noncoding region appears to be a determinant of mrna stability, and endonucleolytic cleavages in the 5' noncoding region may well re ... | 1988 | 3280138 |
| site-specific endonucleolytic cleavages and the regulation of stability of e. coli ompa mrna. | the stability of ompa mrna is growth-rate dependent. we show that the 5' noncoding region of this mrna provides a target for site-specific endonucleases. the rate of degradation of ompa mrna parallels the rate of these endonucleolytic cleavages, implying that endonucleolytic rather than exonucleolytic attack is the initial step in ompa mrna degradation. thus the 5' noncoding region appears to be a determinant of mrna stability, and endonucleolytic cleavages in the 5' noncoding region may well re ... | 1988 | 3280138 |
| complementation of anti-cea and anti-tag-72 monoclonal antibodies in reactivity to human gastric adenocarcinomas. | monoclonal antibody (mab) b72.3 and mab col-4 are reactive with the high-molecular-weight (mr greater than 10(6] tumor-associated glycoprotein (tag)-72, and the mr 180,000 carcino-embryonic antigen (cea), respectively. antibody competition radioimmunoassays (rias) using 125i-mab b72.3 or 125i-col-4 have demonstrated that each mab also recognizes a distinct antigenic determinant. solid-phase rias using mabs b72.3 and col-4, however, demonstrated similar reactivity for each mab with gastric carcin ... | 1987 | 2447021 |