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high oxygen requirements of dyskinetic cardiac muscle.this study assesses the regional oxygen requirements of muscle segments that are beating and working, beating and empty, arrested and decompressed, and nonischemic that move dyskinetically. regional oxygen demands were evaluated by producing a dyskinetic segment by infusing regional cardioplegic solution through a left anterior descending coronary artery catheter with and without extracorporeal circulation. the results show that the o2 demands of the perfused dyskinetic cardiac muscle segment (4 ...19863747582
evidence against systolic intramural forces as the primary cause of subendocardial preponderance of ischemia.verification of the current view that subendocardial preponderance of ischemia is due to greater forces generated in the deep myocardial layer during systole was undertaken. in anesthetized mongrel dogs transient ischemia was produced in two different situations of altered systolic forces. first, in order to remove that part of the systolic force which is related to intracavitary pressure, left ventricular bypass was created and the left ventricle vented. second, in order to even out the transmu ...19863753389
[atracurium (tracrium). a new non-depolarizing neuromuscular blocker]. 19863755261
oligodeoxynucleotide stability in subcellular extracts and culture media.oligodeoxynucleotide degradation was studied in four systems in order to assess the importance of degradation in hybridization arrest experiments dependent on oligodeoxynucleotides complementary to mrna sequences. oligodeoxynucleotides were not detectably degraded over 2 h at 37 degrees c in rabbit reticulocyte lysate or dulbecco's modified essential medium with 5% fetal calf serum, but were degraded over 2 h in hela cell postmitochondrial cytoplasmic extract, and were degraded within 15 min in ...19863772027
[evoked spinal potentials in the wistar rat: effect of cord compression and drugs].changes of the evoked spinal cord potential (esp) were measured in wistar rats by giving acute compression to the spinal cord injury. the effects of naloxone, methylprednisolone and prostaglandin e1 on esp of the damaged spinal cord were also closely examined. normal esp of rats showed two negative peaks, an initial wave (the 1st potential) and a subsequent gentle and small wave (the 2nd potential). after placing a 10 g weight on the spinal cord, the potential decreased in amplitude and prolonge ...19863772215
effects of testosterone, estrogen, and dihydrotestosterone upon aggressive and sexual behavior of female rats.groups of female tmd rats were treated either with estradiol benzoate (eb), dihydrotestosterone propionate (dhtp), testosterone propionate (tp), eb + dhtp (eb/dhtp), or with oil. these groups of females were tested for social aggression and for masculine and feminine sexual behavior. in addition, patterns of masculine and feminine sexual responses during the aggressive encounters, were investigated. tp-treated females of the same strain were used as opponents in the tests for aggression. in acco ...19863793023
a theoretical model to study the effect of convection and leaky junctions on macromolecule transport in artery walls.a mathematical model is presented herein to determine the effect of convection on macromolecular transport across an artery wall due to transmural or osmotic pressure differences. the model is based on an extension of the leaky junction-cell turnover model of weinbaum et al. (1985) to take into account a combined transport mechanism of convection and diffusion and also to provide the leaky junctions in the model with a finite resistance, thus allowing the results to be extended to intercellular ...19863795993
response of dogs to challenge with ancylostoma ceylanicum during the tenure of a primary hookworm infection.a model of human hookworm infection has been developed which shows that dogs currently infected with small numbers of hookworms are considerably resistant to a challenge infection with a large inoculum of infective larvae. two groups of dogs were infected with 500 larvae and four weeks after infection one group together with a previously uninfected control group were infected with 5,000 larvae and followed for six weeks. when compared with the secondary infection control dogs, faecal egg excreti ...19863798534
osteocalcin in human serum: a circadian rhythm.osteocalcin, the vitamin k-dependent protein synthesized in bone, is found in blood. the level of circulating osteocalcin has recently been used as an indicator of the rate of bone turnover. we measured serum osteocalcin during 24-h periods in 6 normal 20- to 30-yr-old men and 4 women. blood was sampled via an indwelling venous catheter every 30 or 60 min for 24 h. circadian rhythmicity in circulating osteocalcin was found in 9 of the 10 individuals studied. osteocalcin levels fell during the mo ...19853871789
[production of tetanolysin preparations and characteristics of their properties].as the result of the study of tetanolysin-producing clostridium tetani strains, their populations have been found to be markedly heterogeneous with respect to the hemolytic activity of clone cultures. on the basis of normal and dialyzed cultures of selected variants with maximum activity the preparations of tetanolysin have been obtained, and their hemolytic activity and antigenic properties have been studied. antihemolytic rabbit sera have also been obtained and characterized. partially purifie ...19853898671
[production of tetanolysin preparations and characteristics of their properties].as the result of the study of tetanolysin-producing clostridium tetani strains, their populations have been found to be markedly heterogeneous with respect to the hemolytic activity of clone cultures. on the basis of normal and dialyzed cultures of selected variants with maximum activity the preparations of tetanolysin have been obtained, and their hemolytic activity and antigenic properties have been studied. antihemolytic rabbit sera have also been obtained and characterized. partially purifie ...19853898671
[changes in the mucous membrane of the trachea and bronchi in dogs based on bronchoscopic data for the combined action of 239pu and gamma-radiation as compared with the individual actions].it was established that under conditions of combined exposure of dogs to external gamma- and internal alpha-radiation, a preirradiation with 51.6 mc/kg gamma-rays prevents the development of the signs of endobronchitis which are typical for endobronchitis induced by inhalation of submicron 239pu dioxide and manifested by hyperemia of trachea and bronchus mucosa, edema, and the presence of mucopurulent exudate.19853909215
cloning and characterization of mefloquine-resistant plasmodium falciparum from thailand.resistance to mefloquine in plasmodium falciparum has begun to occur along the border of thailand and kampuchea. as a means of assessing the natural occurrence of mefloquine resistance, the admission and post-treatment parasite isolates from a mefloquine treatment failure were cloned and characterized. clones from the admission isolate were susceptible to mefloquine in vitro (id50 of 3.4 [2-5], g [95% ci] ng/ml) and showed a mixture of isozyme types for glucose phosphate isomerase (gpi types i a ...19853914841
structure of the linkage units between ribitol teichoic acids and peptidoglycan.the structure of the linkage regions between ribitol teichoic acids and peptidoglycan in the cell walls of staphylococcus aureus h and 209p and bacillus subtilis w23 and ahu 1390 was studied. teichoic acid-linked saccharide preparations obtained from the cell walls by heating at ph 2.5 contained mannosamine and glycerol in small amounts. on mild alkali treatment, each teichoic acid-linked saccharide preparation was split into a disaccharide identified as n-acetylmannosaminyl beta(1----4)n-acetyl ...19853918002
consequences of the o2-co2 dissociation curves for gas exchange in avian and mammalian lung at various altitudes.gas exchange in avian and mammalian lung was studied with computer simulations using mutually dependent o2-co2 dissociation curves. the mammalian lung was simulated with an ideal mixing unit. the model of the avian lung consisted of 25 ideal mixing units placed in series with respect to the ventilation but placed in parallel with respect to the perfusion (cross-current arrangement). the consequence of the right shift in the avian oxygen dissociation curve, if compared with the human dissociation ...19853938606
a model for the ca2+-induced conformational transition of troponin c. a trigger for muscle contraction.the initial contractile event in muscle is the binding of ca2+ ions to troponin c of the troponin complex, leading to a series of conformational changes in the members of the thin and thick filaments. knowledge of the crystal structure of turkey skeletal muscle troponin c has provided a structural basis for the modeling of the first stage of this process in atomic detail. this crystal structure probably represents the molecule in the relaxed state of muscle, with two of the maximum of 4 ca2+ ion ...19863949740
a model for the ca2+-induced conformational transition of troponin c. a trigger for muscle contraction.the initial contractile event in muscle is the binding of ca2+ ions to troponin c of the troponin complex, leading to a series of conformational changes in the members of the thin and thick filaments. knowledge of the crystal structure of turkey skeletal muscle troponin c has provided a structural basis for the modeling of the first stage of this process in atomic detail. this crystal structure probably represents the molecule in the relaxed state of muscle, with two of the maximum of 4 ca2+ ion ...19863949740
gastric dilation in bloodhounds. 19863962133
[principles of organization of tissue mosaics of simple squamous epithelia].with the aim to study general principles on organization of tissue mosaics of various types of simple squamous epithelii, a quantitative topological analysis has been performed in the frog mesothelial mosaics, in the posterior epithelium of the rabbit cornea and in the rat aortal endothelium after lewis method. to all the types of simple squamous epithelii studied the histological law of lewis can be applied. as demonstrates the qualitative analysis of the mosaics, the mesothelium and the poster ...19853994528
pancreatic stone protein. i. evidence that it is encoded by a pancreatic messenger ribonucleic acid.we have previously shown that the pancreatic stone protein (psp) is an inhibitor of calcium carbonate crystal growth and may participate in the stabilization of the normally supersaturated pancreatic juice. our aim in this study was to determine if psp is a normal secretory product of the human pancreas by determining if the normal human pancreas contains a messenger rna coding for psp. human pancreatic messenger rnas were used to direct protein synthesis in a cell-free translation system. immun ...19854007427
necrotizing soft-tissue infections caused by marine vibrios.halophilic, noncholera marine vibrio bacteria can cause septicemia, gastroenteritis, cellulitis, and necrotizing fasciitis. we describe six patients with necrotizing fasciitis and review 12 cases described previously. the 18 patients included 14 men and four women. their ages ranged from 32 to 79 years (average 58.1 years). eleven patients were older than 55 years. nine infections were caused by v. vulnificus, three by v. parahaemolyticus, and one by v. alginolyticus. in five cases the vibrio sp ...19854012603
a rapid method for culturing guinea pig gastric mucous cell monolayers.a method has been developed for growing confluent primary cultured monolayers of guinea pig gastric mucous cells suitable for in vitro electrophysiological, transport, and pharmacological studies. isolated mucous cells were enriched on a one-step percoll density gradient and plated on fibronectin-coated plastic dishes or in small cups with holes containing glutaraldehyde-fixed vitrogen gels. these cups were designed to fit in ussing chambers. mucous cells attached, proliferated, and formed confl ...19854030627
[in vivo experimental modelling of the infectious process caused by stable l forms of the causative agent of typhoid].to simulate the infectious process and to study the persistence of l-forms, rabbits and guinea pigs were infected with s. typhi stable l-forms. the materials presented in this work indicate that both subconjunctival and intraperitoneal infection led to the development of the clinically indistinct, but morphologically pronounced pathological process with characteristic localization and typical changes in the gastrointestinal tract. the typical features of the process were the generalized immunomo ...19854060947
reduced nicotinamide-adenine dinucleotide-nitrite reductase from azotobacter chroococcum.1. the assimilatory nitrite reductase of the n(2)-fixing bacterium azotobacter chroococcum was prepared in a soluble form from cells grown aerobically with nitrate as the nitrogen source, and some of its properties have been studied. 2. the enzyme is a fad-dependent metalloprotein (mol.wt. about 67000), which stoicheiometrically catalyses the direct reduction of nitrite to nh(3) with nadh as the electron donor. 3. nadh-nitrite reductase can exist in two either active or inactive interconvertible ...19734147887
cooperative interactions in enzymes: the binding of 1, n6-etheno-atp to aztobacter vinelandii nitrogenase. 19734133565
cytogenetic engineering in vivo: restoration of biologic complement activity to c5-deficient mice by intravenous inoculation of hybrid cells.splenic macrophages were identified as at least one source of c5 elaboration in normal mice. hybrid cells were formed from splenic macrophages from c5-deficient mice and either kidney cells from mice with normal amounts of c5 or chicken erythrocytes. these hybrids elaborated c5 in vitro. c5-deficient mice inoculated with these hybrid cells developed, in their serum, antigenically active mouse c5, as well as both hemolytic and biologic complement activity. these studies demonstrate the feasibilit ...19734131744
quantitation of canine immunoglobulins. 19704195498
effects of dextrans on immunoprecipitation in agar and in low-temperature-gelling agarose gels. 19744215837
[modifications in relation to age in the number and diameter of nerve fibers in dorsal spinal roots of the rat]. 19854062475
effect of salicylates on human platelets. 19684173780
oxygen consumption of the germinal epithelium in psoriatic human skin as measured by the cartesian diver micro-gasometer. 19684185292
[morphological changes in the pancreas and islands of langerhans in rats during induced hyperglycemia and hypoglycemia]. 19744279158
[pharmacokinetics of antimicrobial agents. lividomycin]. 19724353341
vascular connective tissue under the influence of oestrogens. ii. reaction of the aortic wall to noradrenaline-induced injury in female and male rabbits. 19664224610
decreased effect of phenobarbital treatment on microsomal drug metabolizing enzyme activity during gestation. 19744275256
morphological changes in the rat hypothalamus and adrenal cortex in the early postnatal period after acth and hydrocortisone administration, stress, and adrenalectomy. 19684302635
a micro assay for mouse and human interferon. ii. dose-response in different in cell-virus systems. 19734360138
[humoral immunity in goats of different ages with q-fever]. 19744454876
conditions of isolation of infectious ribonucleic acid from influenza virus. 19664380455
bone marrow transplantation. 19714398503
comparative effects of glucagon on automaticity of the sinus node and atrioventricular junction. 19744440785
a medium for the recognition and enumeration of streptococcus mutans. 19724503997
modern concepts of neonatal disease in foals. 19724568905
an inhibitor of host sigma-stimulated core enzyme activity that purifies with dna-dependent rna polymerase of e. coli following t4 phage infection. 19734585685
a medium for the recognition and enumeration of streptococcus mutans. 19724503997
stimulation of partial limb regeneration in rats. 19724550399
[dna content of the colicinogenic factor e1 in escherichia coli cells with different growth rates]. 19744601345
differential effects of antibiotics on peptidyl transferase reactions. 19724555251
the rapid and large scale separation of peritoneal macrophages. 19724622703
in-use evaluation of a commercially available set of quality control cultures.increasing awareness of the need for a uniform quality control program prompted an evaluation of a commercially available set (bact-chek) of eight organisms. a protocol was designed in which this set of control cultures was tested simultaneously in the clinical microbiology laboratory of a 400-bed hospital (the berkshire medical center) and in the reference laboratories of the bacteriology section of the center for disease control. the results indicate that the bact-chek organisms are essentiall ...19734632850
[comparative study of the physico-chemical properties and chemical structure of the hemoglobin and myoglobin of sciurus vulgaris protein]. 19734709881
intrahemocoelic infection of ticks ornithodoros moubata (murray) due to rickettsia prowazeki and the influence of some antibiotics on growth curve of this bacteria. 19724634100
mechanisms of demyelination in the human demyelinating diseases and in the experimentally induced demyelinating conditions in animals. 19724635583
no sparing of function following serial posterior neodecortication in rats given interoperative training. 19734689147
[to the question of correct bacteriological conception of urogenitalinfections]. 19684972284
[functional relationship between lnpf (vascular permeability factor of ganglia) and histones]. 19694981852
isopropyl carbanilate (propham) metabolism in the chicken: balance studies and isolation and identification of excreted metabolites. 19725066259
[studies on experimental bronchitis and obstructive emphysema]. 19734794148
computed tomographic evaluation of the breast.experience with a dedicated breast ct scanner (general electric ct/m) using a contrast medium enhancement technique indicates that ct is superior to mammography, thermography, or physical examination for diagnosing both benign and malignant mammary disease especially in dense, thick, or fibrocystic breasts. ct is capable of diagnosing totally unsuspected early miniature carcinomas. it can identify and differentiate potential precancerous lesions from benign fibrocystic disease, and is the diagno ...200098990
[neural coding of motor commands]. 2001138916
[primary transport of acute patients. optimal use of rescue resources exemplified by the canton of graubünden]. 20113927607
[seminar on nursing administration. ford development of labor and industrial relations]. 20113204975
second-trimester abortion after vaginal termination of pregnancy. 20144115252
dna damage and its repair in transformable mouse fibroblasts treated with n-methyl-n'-nitro-n-nitrosoguanidine. 19744833913
histological investigations of intravascular coagulation in rats with gradual occlusion of the portal vein. 19734747060
role of the duodenum in vitamin d3 absorption in man. 19715100749
isolation of monocytic serine esterase and evaluation of its proteolytic activity.monocytes are characterized by high activity of alpha-naphthyl acetate esterase (anae), distinguishing them from all other blood cells. the physiological function of this monocyte marker enzyme has not yet been elucidated. in this study anae's potential proteolytic activity was analyzed because serine esterases/proteases can function as effector molecules in cell-mediated cytotoxicity and because monocytes-macrophages are known to exert cytotoxic effects on tumor cells. this enzyme was purified ...20061564403
[derivative spectroscopy and its use in sanitary hygiene control].an analytical method is developed for defining the residual quantities of rodenticide "brodifacoum" (talon) used in the control of harmful field rodents and especially for species microtus. the method is based on extracting the pesticide with chloroform and making use of spectrophotometry in the ultraviolet field in intervals 340-240 nm. the second derivative of the absorption is utilized as well as the band with maximum 288 nm and minimum 228 nm. the peak height in this interval is in proportio ...20072099444
the euiryong experiment: a korean innovation in household contraceptive distribution.although contraceptive practice has increased substantially in korea as a result of a strong national family planning program, surveys indicate the existence of an additional unmet demand. a number of obstacles tend to limit availability of family planning services and supplies. the effects of total availability are being tested in a three-year experiment in household contraceptive distribution, for which an exploratory study was carried out in 1975 in euiryong gun. three distribution systems we ...2003403640
[a new diagnostic test for acute myocardial infarction-immunologic measurement of myoglobin (author's transl)]. 2003430882
[practical evaluation of methods in pharmacokinetics].a short discussion of the differences between kinetic processes of zero and first order is followed by an outline of evaluation methods used in pharmacokinetic practice, e.g. "paper and pencil methods" as well as the use of digital and analog computers. the increasing potency of new drugs requires not only more sophisticated methods of analysis and expensive facilities but also more complex models to generate pharmacokinetic information.20051242344
[clinical study of osteoporosis]. 20082614196
decreased sensitivity of atopic mononuclear cells to prostaglandin e2 (pge2) and prostaglandin d2 (pgd2).the effect of pge2 and pgd2 on several lymphocyte functions in vitro was evaluated in nonatopic and atopic subjects. both pge2 and pgd2 inhibited phytohemagglutinin-induced protein synthesis ([3h] leucine uptake) by nonatopic mononuclear cells and t cells in a dose-dependent manner (10(-6) to 10(-12) m). protein synthesis by atopic mononuclear cells was not significantly suppressed by the above concentration of pge2. although pgd2 effectively suppressed protein synthesis by atopic mononuclear ce ...20093160784
regulation of alcohol consumption by the renin-angiotensin system: a review of recent findings and a possible mechanism of action.the renin-angiotensin system has traditionally been associated with the regulation of fluid and electrolyte balance. in this review we summarize the data which ascribes a completely new function to this system, i.e., the regulation of alcohol consumption. in addition, we suggest a possible mechanism for this effect based on the concept of a satiety or stop process. the approach taken was to examine the effect on alcohol intake of a wide variety of drug, genetic, dietary, surgical and neurosurgic ...20071852316
[testicular damage in elastorrhexis generalisata]. 20165031134
[therapy of peptic ulcer using desoxycorticosterone acetate (doca)]. 20154666352
[epidemiology of dental caries and periodontal disease in guatemala]. 20123269012
the circadian rhythms of acetabularia (primarily photosynthesis) [proceedings]. 200094815
[current approaches to immunological diagnosis of autoimmune and immune complex diseases]. 20102974642
insensitivity, limited joint mobility, and plantar ulcers in patients with diabetes mellitus.the purpose of this study was to determine whether differences in sensation, ankle dorsiflexion (df), and subtalar joint (stj) motion exist between 1) diabetic patients with a history of plantar ulcer (dmw group), 2) diabetic patients without a history of plantar ulcer (dmwo group), and 3) a nondiabetic control group (ndc group). there were 23, 23, and 24 subjects in the respective groups. the mean age for each group was 58, 63, and 60 years, respectively. the mean df for each group was 2, 5, an ...20092727069
[determination of serum acth]. 2002186651
long-term follow-up (5-12 years) of proliferative diabetic retinopathy treated with xenon arc photocoagulation. 200195033
sequence dependent dna conformations: raman spectroscopic studies and a model of action of restriction enzymes.raman spectra have been examined to clarify the polymorphic forms of dna, a, b, and z forms. from an analysis we found that the guanine ring breathing vibration is sensitive to its local conformation. examination of nine crystals of guanosine residues in which the local conformations are well established revealed that a guanosine residue with a c3'endo-anti gives a strong line at 666 +/- 2 cm-1, o4'endo-anti at 682 cm-1, c1'exo-anti at 673 cm-1, c2'endo-anti at 677 cm-1 and syn-forms around 625 ...20103010660
xeromammography at a community hospital. a year's experience. 20051183210
community care--up in the air? 20092771747
problems related to diet management of maternal phenylketonuria.provision of nutritionally complete elemental diets for pregnant women with pku requires greater knowledge of 'conditionally' essential nutrient requirements than is presently available as well as application of known information. formulation of elemental products needs to be improved to enhance aroma and taste and to decrease osmolality. designers of the metal and vitamin components should keep in mind that a major portion (70-80%) of most of these nutrients must be obtained from the elemental ...20102877116
children's toys. 20123348046
loss of ambulatory ability in patients with old anterior poliomyelitis. 20124117381
threat to the phls. 20143918677
[cytological diagnosis of metastatic lesions of the lymph nodes]. 20154575426
electromyography in the diagnosis and treatment of myasthenia gravis. 20144300143
electromyography in the diagnosis and treatment of myasthenia gravis. 20144300143
[organizing a visiting service for the isolated elderly]. 20154495716
[changes in lymphocytes in acute suppurative-destructive lung diseases].a study of the content of lymphocytes and their populations, indices of intracellular viral involvement of the lymphocytes in 32 patients with acute purulent-destructive pulmonary diseases and 46 healthy persons revealed an increase of the percent of non-viable lymphocytes containing viral inclusions. viral involvement of lymphocytes is considered one the leading causes of increased lymphocyte death.20082588523
incidence and causes of sepsis in glucose-6-phosphate dehydrogenase-deficient newborn infants.to determine the susceptibility to sepsis in newborn infants deficient in glucose-6-phosphate dehydrogenase (g6pd), we screened 33,943 saudi arab infants. deficiency of g6pd was found in 18%. sepsis was determined by the presence of clinical signs of sepsis and confirmed by positive blood cultures. sepsis was documented in 75 infants (2.2/1000). the incidence of sepsis was significantly higher in 6138 g6pd-deficient infants (3.4/1000) than in the 27,805 with normal g6pd activity (1.9/1000; p les ...20092715888
handlight retroillumination in hotv visual acuity testing. 20134062629
complications of the burn injury.complications secondary to thermal, chemical, or electrical injury are varied and involve organ systems other than the skin. they proceed, to some degree, in a chronologic sequence and can thus be anticipated.20133870968
strength training for children.the indications for progressive resistive strength training for prepubescent children in sports training and rehabilitation have been a source of controversy. eighteen prepubescent children, two at tanner stage ii and the remainder at tanner stage i, were studied. examination included anthropometric upper and lower extremity strength and flexibility measurements. the study group participated in progressive resistive strength training sessions on machines three times per week. the study group had ...20143958165
immunohistochemical study of lysozyme in lupus miliaris disseminatus faciei.the lysozyme activity in tissue samples from patients with lupus miliaris disseminatus faciei (lmdf), sarcoidosis and foreign body granuloma was investigated using the immunoperoxidase technique. the majority of epithelioid cells and giant cells in lmdf and sarcoidosis showed strong lysozyme staining in their cytoplasm. however, most macrophages and giant cells in foreign body granulomas, including granulomatous reactions to epidermal cysts and other foreign materials, stained weakly for lysozym ...20133527252
[amyloidosis of the dialysis patient]. 20113077074
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