Publications

oxygen metabolism by the anaerobic bacterium veillonella alcalescens.		1978	31846
basic health services in nigeria: models for primary care in america.	the basic problems in delivery of health care in the united states and in nigeria are similar; the major differences are in magnitude. nigeria's basic health services scheme, now being implemented, is a bold effort to make quality health care accessible to the entire population. american health planners should look to such developing countries for concepts adaptable to our own health care delivery system. in developing primary care programs in particular, they should consider three basic compone ...	1994	43402
an erythrocyte membrane-protein anomaly in march haemoglobinuria.	in three patients with march haemoglobinuria a well-defined protein abnormality has been revealed by high-resolution sodium-dodecyl-sulphate/polyacrylamide-gel electrophoresis.	2000	91785
lisuride in parkinson's disease.		2000	91855
[ecg changes in chronic polyarthritis compared to a healthy control group].	ecg from 200 patients with radiologically and clinically definite rheumatoid arthritis were compared with those from a healthy group with the same age and sex distribution. the frequency of pathological changes of the ecg was found to be the same in both groups. therefore doubt remains whether the pathological changes of the ecg can be attributed to rheumatoid arthritis.	2000	92110
evaluation of pseudorabies viral antigens in the agar gel immunodiffusion test.	procedures designed to extract pseudorabies viral (prv) antigens from prv-infected tissue cultures were investigated to determine whether differences in extraction method had an effect upon the final concentrated antigenic product. all four of the preparations made from prv-infected tissue culture cells (trypsin extract and disrupted cells) or entire prv-infected cultures (polysorbate 80 extract and (nh4)2so4 precipitate) contained relatively large amounts of the same antigen, whereas cell-free ...	1979	92905
characterization of various horse thyroid forms of cyclic-nucleotide phosphodiesterase [proceedings].		1979	92956
immunological heterogeneity of the subunits of limulus polyhemus haemocyanin [proceedings].		2001	92962
partial purification of tumour-specific transplantation antigens from methylcholanthrene-induced murine sarcomas by immobilized lectins.	plasma membranes isolated from two immunogenic, non-cross-protecting, mc sarcomas were shown to retain the specific rejection antigens of whole cells as well as serologically detected h-2 antigens. solubilization of the membranes with sodium deoxycholate gave quantitative release of h-2 and retained the rejection specificity of the tumour from which it was derived. polyacrylamide-gel electrophoresis (page) showed no extensive degradation of membrane components during solubilization. the solubili ...	1999	93484
[investigations into the biological disintegration of organic natural substances by aquatic hyphomycetes (author's transl)].	the ability of 5 aquatic hyphomycetes to produce amylase, pectinase and cellulase was investigated. all the tested strains were weak producers of amylase and good producers of pectinase, whereas degradation of cellulose was only found with two strains.	2000	94494
isoelectric focusing of oligopeptides: detection by specific stains.	by using ultrathin (350 micrometers) polyacrylamide gels, which at the end of the fractionation are pasted to filter paper and dried in an oven at 110 degrees c, and after isoelectric focusing it has been possible to detect oligopeptides in the di- to tetradecapeptide range, which could not be detected by protein staining techniques. this is achieved by developing a series of specific stains for the following amino acids: arg, tyr, his, trp, met and cys. except for met and cys, the detection lim ...	1979	95344
production and chemical studies of protease from bacillus subtilis (sh-6) egyptian strain.	bacillus subtilis (sh-6) egyptian strain, isolated from hides, gave the highest protease activity. luxurious growth and protease production were obtained by the use of a medium containing 8% of potato starch, 0,1 m of ammonium phosphate as carbon and nitrogen sources. results indicate that borate buffer exerted a deleterious effect on the protease production. comparing citrate and phosphate buffers, it was found that citrate gave lower protease activity than phosphate. there is a positive respon ...	1978	98932
imipramine in absence and myoclonic-astatic seizures.	a double-blind crossover study with imipramine was conducted in 10 patients with absence and myoclonic-astatic seizures who had not responded to conventional medications. imipramine produced a significant initial decrease in seizure frequency in 5 of the 10 patients, and in 2 patients the beneficial effect was maintained for more than 1 year. an open trial of imipramine in another 16 patients showed an initial reduction in seizure frequency in 10 patients (63 percent), and this decrease persiste ...	2001	99690
past history and future trends in cme.		2000	101942
anal tonometry and anal tone in clinically healthy persons and patients with chronic diseases of the digestive apparatus.		1999	103788
a report on genetic registers. based on the report of the clinical genetics society working party.		1998	106123
interaction of phenosafranine with nucleic acids and model polyphosphates. iii. heterogeneity in phenosafranine interactions with dna base pairs.	fluorescence and circular dichroism spectral measurements, thermal denaturation studies and binding competition experiments with netropsin and actinomycin d were carried out in systems containing phenosafranine bound to dna's differing in base composition. the investigated properties exhibit a heterogeneity related to the content of a.t and g.c pairs in dna and to the nature of phenosafranine binding modes. at low level of saturation of binding sites (r less than 0.1) phenosafranine does not sho ...	1979	106900
inhibition of passive lung anaphylaxis in the rat by ay-25,674.	the antiallergic properties of ay-25,674 were studied in a model of passive lung anaphylaxis. ay-25,674 caused a dose-related inhibition of antigen-induced bronchoconstriction in the passively sensitized rat. ay-25,674 was found to be twice as potent as disodium cromoglycate (dscg) when injected intravenously. the oral administration of ay-25,674 also effectively inhibited antigen-induced bronchoconstriction. a tachyphylactic effect of repeated administration was found when the rats were pretrea ...	1979	106941
current concepts in portal hypertension.		1998	107346
[typical changes of the intestinal wall due to oral stenosing processes (author's transl)].	two different changes of the intestinal wall, which seem to be of stenotic orgin, can be observed prä-stenotically. one of these changes is represented by diverticulosis, whereas the other is the so-called ischaemic-ulcerous lesion of the mucosa. the latter accompanying disease supplies highly important preoperative information. this condition can be diagnosed practically exclusively by the roentgenologist. in many cases, stenosis makes endoscopic assessment impossible. diverticulosis is of theo ...	2000	111337
[ecological aspects of south american trypanosomiasis. xiii. domestic enzootic potential in an area of occurrence of panstrongylus megistus, under epidemiological surveillance].		1978	111341
[anthropological studies on the cossacks in bulgaria].		2002	126579
the influence of age on the wound healing of experimental myocardial infarction in rats.	in 6-weeks-old, 5-months-old and 21-months-old rats myocardial infarction was induced by coronary artery ligature. after performing the ligature the animals were administered 3h-thymidine, 3h-proline or 35s-sulphate at different times. the following parameters were determined: number of dna- and tropocollagen-synthesizing connective tissue cells at the infarction border and at the infarction site; mean silver grain density above the nuclei or cells; duration of a cycle; number of mitoses, and in ...	1975	134906
the effects of varying digit message structures on their recall by mongols and non-mongol subnormals.		2002	135091
reduced nicotinamide adenine dinucleotide-nitrate reductase of chlorella vulgaris. purification, prosthetic groups, and molecular properties.	nadh:nitrate reductase (ec 1.6.6.1) from chlorella vulgaris has been purified 640-fold with an over-all yield of 26% by a combination of protamine sulfate fractionation, ammonium sulfate fractionation, gel chromatography, density gradient centrifugation, and deae-chromatography. the purified enzyme is stable for more than 2 months when stored at minus 20 degrees in phosphate buffer (ph 6.9) containing 40% (v/v) glycerol. after the initial steps of the purification, a constant ratio of nadh:nitra ...	2003	165192
lipoproteins: structure and function.		2002	166603
myelographic cervical nerve root deformities.	myelograms of nerve roots and adjacent subarachnoid space were reviewed to characterize 231 cervical root deformities from both symptomatic and asymptomatic patients. good correlation between specific features of root deformities and clinical significance could not be demonstrated. some features were slightly suggestive of clinical significance but occurred in a sufficient number of asymptomatic patients to make them unreliable. the most accurate determinants of root deformity significance are c ...	1997	168615
evidence for hydroxyl radical generation by human monocytes.	a number of highly reactive oxygen species have been implicated in the oxygen-dependent mechanisms involved in bactericidal activity of phagocytic leukocytes. hydrogen peroxide and superoxide, two agents known to occur during phagocytosis, are thought to interact to generate hydroxyl radical, singlet oxygen, and other potentially reactive molecules. using an assay system of ethylene generation from methional, cell preparations of human monocytes were demonstrated to generate hydroxyl radical or ...	1977	194926
[statistics point out a great need for safety activities].		1983	242392
[x-ray crystallography in the study of urinary lithiasis. methodological aspects and clinical results].		2003	262274
isolation and surface labeling of murine polymorphonuclear neutrophils.	methods for the induction of an exudate of polymorphonuclear neutrophilic leukocytes (pmn) in the peritoneal cavity of c57bl, balb/c, sjl and cba mice were analysed. peritoneal exudates in male mice were highly enriched for pmn (80-90%) three hours after a single injection of calcium caseinate whereas eosinophils comprised less than 1% of the exudate population. female mice were a less satisfactory source of pmn because the proportion of eosinophilis in the exudate was variable. purification of ...	2000	313932
osteomyelitis and arthritis caused by salmonella typhimurium in a crow.	salmonella typhimurium was isolated from an arthritic elbow joint of a crow (corvus brachyrhynchos) which also had bilateral osteomyelitis of proximal tibias. the prevalence of salmonella organisms in wild birds is reviewed briefly.	1978	368353
[aplastic anemia treated by isogeneic or allogeneic bone marrow transplantation (author's transl)].		2004	368376
potency of 10 bcg vaccines as evaluated by their influence on the bacillemic phase of experimental airborne tuberculosis in guinea-pigs.		1979	387796
a comparison of wisc and wisc-r subtest scatter.		2004	438638
erythrocyte sedimentation rate and plasma fibrinogen in animals.		2004	522104
replanting and transplanting teeth. part three. transplantation of teeth other than canines.		2005	1065351
[hypothetical concept: the physiopathological entity of monoaminergic psychoses].	the importance of amino acid transport across the blood-brain barrier as the limiting factor in the metabolism of monoamines has been emphasized by many recent publications. particularly critical is the transport of tryptophan, since tryptophan hydroxylase is not saturated. this transport is regulated by complex mechanisms, both at the periphery (total and free plasmatic levels and levels of the other essential amino acids) and centraly (by feedback mechanism initiated at the pre- and post-synap ...	1975	1082812
pattern detection and the two-dimensional fourier transform: circular targets.		2005	1166624
the role of prophylactic antibiotics in caesarean section--a randomised trial.	a prospective randomised controlled study was conducted over a 6 month period on the value of administering prophylactic antibiotics in patients undergoing emergency caesarean section at the ipoh general hospital. a total of 222 patients were randomised to receive 24 hours of ampicillin (500 mg per dose), cefoperazone (1 gm per dose) or no antibiotics. in all parameters of patient morbidity, the group receiving cefoperazone showed significantly better results as compared to the group not receivi ...	2003	1303479
ion channel selectivity, permeation, and block.		2006	1382215
value of dundee coronary risk-disk.		2006	1392968
ultrasonographic assessment of osteoporosis.		2006	1393241
thallium-201 accumulation by epidermoid inclusion cyst.	an elderly male undergoing re-evaluation for coronary artery disease demonstrated an extra-cardiac focus of 201tl accumulation during the performance of a planar myocardial perfusion scan. this corresponded to a subcutaneous lesion of the left posterior thorax found on a concurrent computerized axial tomographic (cat) scan and upon surgical excision proved to be an "epidermoid inclusion cyst." a follow-up nuclear scan failed to reveal any residual extracardiac tracer localization. confusing this ...	1992	1403158
coordinated delivery of clinical care: the "re-integration" of the medical group practice.	this paper suggests that for medical knowledge to be effective, it must be reliably translated into a series of synchronized activities, both clinical and operational. the goal of medical information science must be not only to identify the best course of care, but also through the use of systems for the ordering, scheduling, and deployment of staff and resources to assure that the planned course of care is reliably and efficiently delivered in actual practice settings. we present a brief histor ...	2006	1482950
tailoring national guidelines to fit the needs of individual facilities.		2006	1539966
[hyperthyroidism caused by non-neoplastic inappropriate tsh secretion].	we report a case of hyperthyroidism due to non-neoplastic inappropriate thyrotrophin secretion in a 31 year old woman. increased t3 and ths levels after thyroidectomy led us to suspect the diagnose. serum levels were further increased by trh and only partially suppressed by triiodothyronine and computerised axial tomography showed a normal sellar region. these features are characteristic of inappropriate tsh secretion due to thyrotroph resistance to thyroid hormones. bromocriptine and octreotide ...	2006	1595367
cerebral hemodynamics and cerebral blood volume: mr assessment using gadolinium contrast agents and t1-weighted turbo-flash imaging.	to assess the degree and regional pattern of first-pass brain enhancement using dynamic mr imaging.	2006	1595482
selective embolisation of intrahepatic aneurysms.	the radiological techniques that can be used to selectively embolise small arteries have improved markedly in the past few years. this article discusses the use of transcatheter embolisation in the management of three patients with aneurysms involving the intrahepatic arterial tree.	2006	1610327
rating of the lesions in senile dementia of the alzheimer type: concordance between laboratories. a european multicenter study under the auspices of eurage.	the study reported was intended to compare the impressions and analyses of investigators from 11 different laboratories on 2 slides, each from 6 cases with varying quantities of neuropathological change of the type found in alzheimer's disease and normal ageing. the material came from 6 selected female patients over 75 years of age all of whom had been examined in detail and assessed by the blessed test score. two were severely demented, 2 mildly demented and 2 were considered to be normal. unst ...	2006	1698217
characterization of the human gene for a newly discovered carbonic anhydrase, ca vii, and its localization to chromosome 16.	six carbonic anhydrase (ca) isozymes (ca i-vi) in mammals and other amniotes have been described. we have isolated an additional ca gene from a human genomic library and designated its putative product carbonic anhydrase vii (ca vii). the gene is approximately 10 kb long and contains seven exons and six introns found at positions identical to those determined for the previously described ca i, ca ii, and ca iii genes. the finding of a 17-bp gt-rich segment in a position 28 bp downstream of the p ...	1991	1783392
postoperative urinary retention in patients undergoing anorectal surgery.		2006	1796976
design of site-specific protein drugs.	the ability to clone and express proteins at high levels of abundance and purity has led to their increasing consideration as therapeutic agents. the use of various protein engineering and recombinant dna techniques has enabled progression to where proteins can be tailored so that they have not only the ability to interact with a unique (extra)cellular component in order to produce a pharmacological effect, but their structure can be altered so as to achieve a selective biological disposition. t ...	1991	1815386
pathologic review of consecutive radical prostatectomy specimens. nerve sparing versus nonnerve sparing.	retrospective pathologic analysis was conducted of specimens from 88 radical retropubic prostatectomy operations performed between 1982 and 1987 inclusive. the median age of patients was sixty years (range, 46 to 73 years). of the 88 radical prostatectomies performed, 51 were nerve-sparing (40 bilateral) and 37 were nonnerve-sparing (11 unilateral) procedures. preoperative clinical staging was similar in both groups. thirty-five of 37 patients (95%) in nonnerve-staging group and 51 of 51 patient ...	2007	1887533
investigation and treatment of a multiple limb birth.	we report a baby born with three fully developed normally functioning legs. the third leg was attached to the baby's sacrum via an iliac bone at the site of a spina bifida. a primitive perineum was present. innervation of the limb was via a sacral hiatus with a myelomeningocele. a rudimentary peritoneal sac was found at operation containing a blind loop of bowel suspended by a mesentery. the additional leg was found to have no cortical representation using somatic evoked potentials although lumb ...	2007	1892571
aerosol ventilation scintigraphy in the evaluation of bronchopleural fistula: a case report and literature review.	radioaerosol scanning is simple to perform and is widely used in conjunction with perfusion imaging to detect pulmonary emboli. it may also be a valuable tool for the early diagnosis of postpneumonectomy bronchopleural fistula. the authors present an illustrative case in which radioactive aerosol imaging was used to confirm a bronchopleural fistula secondary to pneumonectomy for squamous cell carcinoma.	2007	1913391
university of north carolina caries risk assessment study. iii. multiple factors in caries prevalence.	the baseline caries experienced of approximately 5,000 children in south carolina and maine was used as the dependent variable in caries risk assessment analyses. clinical, microbiologic, and demographic factors served as independent variables in a multivariate relationship to caries through regression and discriminant function analyses. four factors--number of dental visits by the child in the past year, presence of white spot lesions, and both the urgency of need for restorative care and the f ...	1991	1920265
transient diminished airway protection after transhiatal esophagectomy.	fifteen consecutive patients undergoing transhiatal esophagectomy for esophageal carcinoma were studied cineradiographically to evaluate postoperative pharyngeal function. cinepharyngo-esophagograms were obtained preoperatively and 1 week (range: 6 to 10 days) and 1 month (range: 18 to 52 days) postoperatively. one week after transhiatal esophagectomy, new radiographic swallowing abnormalities were identified in 10 patients (67%). the most common abnormalities observed were laryngeal penetration ...	2007	1951906
assessment of abdominal fat deposition in female cynomolgus monkeys.	computed tomography (ct) was used to assess abdominal fat distribution in adult, female cynomolgus macaques (macaca fascicularis). the technique used was similar to that applied in human beings and allowed intra-abdominal, subcutaneous and total abdominal fat to be quantitated in 1 cm thick sections. correlations between single scans and the average of scans at several levels ranged from r = 0.96 to r = 1.00, indicating that a single scan is representative of abdominal fat distribution. signific ...	1991	2045214
the purification and characterization of recombinant human renin expressed in the human kidney cell line 293.	the cdna encoding human preprorenin has been introduced into the adenovirus-transformed human kidney cell line 293. the recombinant 293 cells expressed and secreted prorenin; trypsin was used to activate the secreted prorenin to renin in vitro. the recombinant protein was purified to homogeneity by a single affinity chromatographic step. using synthetic tetradecapeptide, the km was 57.1 +/- 9.3 microm and the kcat was (7.48 +/- 1.57) x 10(3)/hr. activation with trypsin resulted in a secondary cl ...	1990	2203348
[anomalous branching of the inferior thyroid artery from the left vertebral artery].	in a 53 years old woman hospitalized for a suddenly developed picture of vascular insufficiency in the verterobrobasillary vascular bed the authors detected an anomalous division of the left vertebral artery from aortic arch. moreover, at the level of thyroid gland there was the division of inferior thyroid artery from the vertebral artery. we express the opinion that the finding did not participate in the clinical symptomatology.	2006	2225222
antibodies to distal carboxyl terminal epitopes in the v-fms-coded glycoprotein do not cross-react with the c-fms gene product.	the product of the v-fms oncogene is an integral transmembrane glycoprotein that is closely related to the cell surface receptor for the macrophage colony stimulating factor, csf-1. a fragment of the v-fms gene encoding a major portion of the extracellular amino terminal domain, the membrane-spanning segment, and the entire carboxyl terminal tyrosine kinase domain of the glycoprotein was molecularly cloned into an inducible prokaryotic expression plasmid. polypeptide products consisting only of ...	1986	2425481
nifedipine: variability in its kinetics and metabolism in man.		1989	2519350
receptor-independent metabolism of platelet-activating factor by myelogenous cells.	human neutrophils incorporate and metabolize platelet-activating factor (paf). we dissociated these events from paf binding to its receptors. cells were pretreated with either pronase, a paf antagonist (l652731), or excess paf. this reduced paf receptor numbers by 70 to almost 100% but had no comparable effect upon the neutrophil's ability to metabolize paf. furthermore, hl-60 cells efficiently metabolized, but did not specifically bind, paf. thus, paf receptor availability did not correlate wit ...	1989	2546802
[what should be done in a meniscal lesion?].	the treatment of meniscal lesions closely depends on the context in which they occur. in isolated lesions of the medial meniscus, meniscectomy under arthroscopy remains the best method. when the meniscal lesion complicates a rupture of the anterior cruciate ligament, meniscal suture associated with reconstruction of the ligament may be contemplated. in case of degeneration of the medial meniscus or lesion of the lateral meniscus, various therapeutic approaches may be envisaged.	2008	2602876
the behaviour of sensory ganglia in relation to their environment.	the nodose ganglion was removed from rats and transplanted into the denervated tongue and into the denervated or innervated sternocleidomastoid muscle. in another procedure the ganglion was sutured to the distal hypoglossal or sciatic nerve. the ganglia failed to develop motor end-plates on denervated muscle. they did, however, induce formation of taste buds on the lingual epithelium. the regenerated nerve fibres ramified extensively within the connective tissue, invading perivascular tissue and ...	1989	2606773
screening for ischaemic heart disease risk factors at a health fair: low attendance by those at highest risk.	among people attending a heart disease screening project at a health fair in sheffield, only 22 of 425 (5.2%) lived in areas with more than 25% of the population belonging to social classes iv or v. the incidence of heart disease is known to be particularly high in these areas, where 15.1% of the total population live. by analysis of the attendance rates from districts other than those immediately adjacent to the site of the health fair, we found that the strength of this inverse correlation inc ...	2008	2607301
autosomal dominant retinitis pigmentosa: exclusion of a gene from extensive regions of chromosomes 6, 13, 20, and 21.	members of a large pedigree of irish origin presenting with early onset type i autosomal dominant retinitis pigmentosa (adrp) have been typed for polymorphic dna markers from chromosomes 6, 13, 20, and 21. for each marker close linkage to adrp has been excluded by pairwise analyses. using distances fixed from well-established genetic maps of these chromosomes and multipoint analyses with two or three contiguous markers, exclusion of adrp was extended to the areas between markers, resulting in th ...	1989	2613243
biopharmaceutical evaluation of sustained-release ethylcellulose microcapsules containing amoxicillin using beagle dogs.	a beta-lactam antibiotic, amoxicillin, was microencapsulated with ethylcellulose using a solvent evaporation process in liquid paraffin containing sorbitan tristearate as a dispersing agent, and the microcapsules obtained showed first-order drug release. usage of the previous log-log relationship of cefadroxil between in vitro dissolution half-lives (t50) and the experimental release rate constants (k'r) of the drug in vivo, and the nomogram for the design of satisfactory sustained-release prepa ...	1989	2632091
biopharmaceutical evaluation of sustained-release ethylcellulose microcapsules containing amoxicillin using beagle dogs.	a beta-lactam antibiotic, amoxicillin, was microencapsulated with ethylcellulose using a solvent evaporation process in liquid paraffin containing sorbitan tristearate as a dispersing agent, and the microcapsules obtained showed first-order drug release. usage of the previous log-log relationship of cefadroxil between in vitro dissolution half-lives (t50) and the experimental release rate constants (k'r) of the drug in vivo, and the nomogram for the design of satisfactory sustained-release prepa ...	1989	2632091
dna-dna hybridization studies and phenotypic characteristics of strains within the 'streptococcus milleri group'.	twenty-five strains resembling 'streptococcus milleri' were compared by dna-dna hybridization, by whole-cell-derived polypeptide patterns on sds-page, and by biochemical tests. four homology groups were revealed by dna-dna hybridization. dna homology groups 1, 2 and 3 were closely related and contained the type strains ncdo 2226 (streptococcus constellatus), ncdo 2227 (streptococcus intermedius) and nctc 10713 (streptococcus anginosus), respectively. dna homology group 4 consisted of four strain ...	1989	2632666
[improvement in the interpretation of the lh-lh perfusion test].		2009	2660763
current management of salivary gland tumors. part 2.	the authors base their treatment of salivary gland malignancies on the size of the primary and the histopathologic diagnosis. group 1 includes smaller tumors in the t1 and t2 classification with cell types that are associated with slow growth. a parotidectomy is usually sufficient therapy for tumors in this group. group 2 contains t1 and 2 tumors with more aggressive behavior. total parotidectomy is indicated here, with postoperative radiotherapy. t3 tumors and patients with nodal metastasis or ...	1989	2701414
single unit response of suprachiasmatic neurons to arginine vasopressin (avp) is mediated by a v1-like receptor in the hamster.	a large population of local circuit neurons within the suprachiasmatic nucleus (scn) exhibit immunopositive staining for arginine-vasopressin (avp). avp has been reported to be released from scn neurons in a circadian pattern that peaks during the subjective day. using an in vitro hypothalamic slice preparation, the present study investigated how scn neurons respond to avp over the circadian cycle and whether the response to avp is mediated by v1- or v2-like avp receptors. exposure of the slice ...	2009	2702494
blunt injury of the abdominal aorta.		2009	2716321
final maturation and ovulation provoked by supply of homologous hypophysis in hoplias m. malabaricus (pisces, erythrinidae).	the final maturation and the ovulation were induced in recently collected specimenes of hoplias m. malabaricus that show oocytes with complete vitellogenesis, by using homologous hypophysis. the hormonal supply was a gradual and positive results were obtained with 9 to 10 hypophysis/kg injected according to 3 different methods. the time of oocytes' maturation from the first dose ranges between 32 and 60 hours a 18 degrees c. the stages of maturation of the oocyte were controlled by intraovaric c ...	2009	2762598
why aged men become impotent.	despite frequent erectile impotence in aged men, etiologic data are scarce. we evaluated 121 impotent male veterans (mean age, 68 +/- 5.3 years) to obtain information on potential pathophysiologic mechanisms. subjects related a complete medical history and underwent physical examination, metabolic assessment, nocturnal penile tumescence monitoring, and vascular and neurologic assessment. the most frequent cause of impotence was the coexistence of neurologic and vascular disorders (30.3%). other ...	2009	2786397
dermal graft harvest technique for use in temporomandibular joint disc repair.		2009	2795307
heavy- and free light-chain myeloma associated with peripheral polyneuropathy.	peripheral polyneuropathy, a rare complication of multiple myeloma, is generally associated with heavy-chain m-proteins and, in very rare instances, with free light-chain myeloma proteins. here we describe a case of multiple myeloma and polyneuropathy with both monoclonal igg and free lambda light chains in the blood. the patient also had free lambda light chains in the cerebrospinal fluid and urine.	2010	2848651
glucagon, glicentin, proglucagon, pyy, pp and propp-icosapeptide immunoreactivities of rectal carcinoid tumors and related non-tumor cells.	glucagon/pp-related peptides were detected immunohistochemically in 18 out of 22 cases of rectal tumors investigated. the reactive tumors showed prevalence of trabecular or mixed trabecular-acinar structure and moderate staining with grimelius' silver and lead-hematoxylin. three of the remaining 4 cases were characterized by reactivity for 5-hydroxytryptamine only, prevalence of a solid nest structural component and intense staining with grimelius' silver technique and lead-hematoxylin. fifteen ...	1987	2882565
insurers, hmos and bc/bs plans talk about aids.		2010	2910793
topical hemostatic agents for dermatologic surgery.		2010	2921403
trefoil balloon for percutaneous valvuloplasty.	a new balloon (trefoil balloon) was developed to avoid complete interruption of blood flow during percutaneous balloon valvuloplasty. it consists of three identical 2- to 4-cm-long angioplasty balloons mounted in a parallel fashion on a single catheter. filled simultaneously, they assume the cross section of a rosette, allowing for continued blood flow. trefoil balloons of various sizes were tested in five dogs (aorta and aortic valve). they created a gradient ranging from 5 to 40 mmhg where con ...	1986	2944597
human milk-derived lactoferrin inhibits mitogen and alloantigen induced human lymphocyte proliferation.	purified lactoferrin (lf), isolated from human milk, was tested for its effect on human t-lymphocyte proliferative responses to phytohemagglutinin (pha) and to alloantigens in mixed lymphocyte culture. lf inhibited proliferation in both assays in a dose-dependent manner. the suppressive effect was not due to lf mediated cytotoxicity since washing cells that had been pre-incubated with lf restored their proliferative activity. lf was most effective in suppressing the pha response when added withi ...	1987	2963123
[current approaches to immunological diagnosis of autoimmune and immune complex diseases].		2010	2974642
dental discrimination?		2010	2975208
high-level production of the ecori endonuclease under the control of the pl promoter of bacteriophage lambda.	escherichia coli strains overproducing the ecori restriction endonuclease have been constructed, using lambda pl promoter expression vectors. in a first step we constructed endri::lacz gene fusions by fusing the n-terminal part of the endri gene with a lacz gene fragment, whereafter the hybrid gene was positioned randomly under the control of the pl promoter to optimize the level of expression. these plasmids direct the synthesis of large amounts of fusion protein approaching 30% of the total ce ...	1985	2996986
calmodulin-mediated cadmium inhibition of phosphodiesterase activity, in vitro.	ion-stripped bovine brain calmodulin (cam) binds 4 moles cd2+ as well as 4 moles ca2+ per mole protein, with similar affinity; in the presence of 1 mm mg2+ the molar binding ratio of cam for ca2+ decreased to 3, the apparent k0.5 for ca2+ nearly doubled, but the binding characteristics of cam for cd2+ were not changed. saturating concentrations ca2+ did not affect the molar binding ratio of cam for cd2+, but increased the apparent k0.5 for cd2+; vice versa, saturating concentrations cd2+ decreas ...	1987	3034196
prostaglandin inhibition of acid is camp dependent.	prostaglandin e (pge) potently inhibits acid secretion stimulated by histamine, but not by acetylcholine or gastrin, and is accompanied by decreased intracellular camp. adenylate cyclase receptor systems are composed of three complex proteins: cell receptor, nucleotide binding protein, and the catalytic subunit. the exact mechanism of pge interaction with this complex remains unclear and elucidation of this site of action is the purpose of this study. we utilized molecular probes directed at the ...	1987	3035281
physiology of alpine skiing.	physiological profiles of elite alpine skiers reveal the importance of muscular strength, anaerobic power, anaerobic endurance, aerobic endurance, coordination, agility, balance, and flexibility. on-hill snow training and dryland training programmes should focus on the elevation of these fitness components. physical characteristics of elite skiers reveal an average height and body mass. today, successful skiers are taller and heavier than their predecessors. slalom skiers tend to be leaner than ...	2011	3067309
localization of the kras2 oncogene in the domestic rabbit (oryctolagus cuniculus).	the kras2 gene was localized in the rabbit by chromosomal in situ hybridization, using a 3h-labeled human cdna probe. there were 201 silver grains on 144 metaphase spreads; 12.9% of the grains resided on chromosome 16, and 54% of these grains were located close to the centromere at 16p11----q11. statistical analysis indicated that labeling at this region represents a significant deviation from a random distribution and thus provided evidence for the assignment of kras2 to 16p11----q11. in additi ...	1988	3073912
echinococcus granulosus: absorption of cycloleucine and alpha-aminoisobutyric acid by protoscoleces.	protoscoleces of echinococcus granulosus absorb the amino acids cycloleucine and alpha-aminoisobutyric acid (aib) by a combination of mediated uptake and diffusion. after correcting for the latter, values for kt and vmax of 0.124 mm and 0.947 nmoles/mg protein/2 min for cycloleucine were calculated; corresponding values for aib were 0.039 mm and 0.139 nmoles/mg protein/2 min. both amino acids were accumulated against a concentration gradient and a comparison of kt and ki values determined in mut ...	1986	3083393
cerebral perfusion pressure: a hemodynamic mechanism of mannitol and the postmannitol hemogram.	sixteen patients each received infusions of 1 g of mannitol per kg over 5 to 10 minutes, and serial determinations of intracranial pressure (icp), systemic arterial blood pressure (sabp), central venous pressure, cerebral perfusion pressure (cpp), hematocrit, hemoglobin, serum na+, k+, osmolarity, and fluid balance were carried out for 4 hours. urine output was replaced volume for volume with 5% dextrose in 0.45% nacl solution. we tested the hypothesis that patients with high (greater than or eq ...	2010	3116451
thyroid function in affective disorders and alcoholism.	the psychoneuroendocrinology of mood disorders and alcoholism is reviewed here. for reasons of both space and clarity, the article focuses on the clinical data and largely omits the basic science data.	2011	3132602
[contributions to clinical myology. classification].		2011	3136470
participation of endothelial cells in murine schistosomiasis.	the endothelial cells participate in the morphological events occurring during murine schistosomiasis, taking part in the development of hepatic periovular granuloma. the cells also show an increase in the expression of factor viii-related antigen in the portal vessels and hepatic sinusoids during the infection. endothelial cells are suggested to play an important role in the pathogenesis of the disease and in the balance of the coagulant-anticoagulant mechanisms which favor the intravascular su ...	2011	3150298
haemolytic uraemic syndrome associated with faecal cytotoxin and verotoxin neutralizing antibodies.	forty-nine patients with a diagnosis of idiopathic haemolytic uraemic syndrome (hus) were investigated to determine evidence of infection by verotoxin-producing escherichia coli (vtec). free faecal cytotoxin active on vero cells (vt) was detected in 15 out of 49 patients (31%). seroconversion or high titres of vt-neutralizing antibodies were detected in 11 out of 18 patients (61%). the results of the present study suggest an association between hus and infection by vtec.	1988	3153027
nephrotoxic drugs.	the nephrotoxic effects of cyclosporine, aminoglycoside antibiotics, cisplatin, amphotericin b, beta-lactam antibiotics and indomethacin are reviewed. these drugs were chosen because they are among the most frequent causes of renal injury in children. in addition, their nephrotoxicity is caused by different mechanisms. several generalizations can be made, however. first, agents which cause tubular damage tend to be synergistic in their toxic effects. this synergism is seen when several nephrotox ...	2011	3153061
recall strategies reported to be used by general dental practitioners in scotland.		2011	3165659
nifedipine induced gingival hyperplasia.		1998	3182672