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[screening for cardiovascular risk factors in a large workplace].a screening investigation was carried out in a large industry in the copenhagen region and 1,472 of the employees were offered examination of blood cholesterol and measurement of blood pressure. at this examination the employees completed a one-page questionnaire about other cardiovascular risk factors. 45% of those invited participated in the investigation, the poorest participation was among women and the greatest among the male officials. on account of the limited number of female employees, ...20072238226
[screening for cardiovascular risk factors in a large workplace].a screening investigation was carried out in a large industry in the copenhagen region and 1,472 of the employees were offered examination of blood cholesterol and measurement of blood pressure. at this examination the employees completed a one-page questionnaire about other cardiovascular risk factors. 45% of those invited participated in the investigation, the poorest participation was among women and the greatest among the male officials. on account of the limited number of female employees, ...20072238226
[aids and dementia].two case histories are presented of patients with aids. in both cases, the initial symptom, apart from the generalized symptoms, was rapidly progressive dementia. the most important neurological symptoms in the aids dementia complex are reviewed and the cns complications of aids are mentioned. in patients with atypical neurological clinical pictures, the diagnosis of aids should be considered.20072238215
[aids and dementia].two case histories are presented of patients with aids. in both cases, the initial symptom, apart from the generalized symptoms, was rapidly progressive dementia. the most important neurological symptoms in the aids dementia complex are reviewed and the cns complications of aids are mentioned. in patients with atypical neurological clinical pictures, the diagnosis of aids should be considered.20072238215
decline in the prevalence of childhood deafness in the jewish population of jerusalem: ethnic and genetic aspects.a longitudinal study was performed on 147 jewish children with bilaterally sensorineural hearing loss of moderately severe to profound degree, born in jerusalem during the eighteen years 1968-85. the prevalence rate of these children declined during the years 1977-85, and at the same time the rate of consanguinity of their parents decreased; this decline was more evident in the genetic group among children with non-ashkenazi ethnic origin. no such decline was found among the ashkenazi children a ...20082230571
transesophageal echocardiography to detect atrial clots in candidates for percutaneous transseptal mitral balloon valvuloplasty.left atrial thrombi are common in patients with mitral stenosis. when percutaneous balloon mitral valvuloplasty is performed on such patients, there is a potential risk of thrombus dislodgment and embolization. in this study conventional transthoracic echocardiography and transesophageal echocardiography were performed for percutaneous balloon mitral valvuloplasty on 19 consecutive candidates (6 men, 13 women, 23 to 81 years old). in five patients (26%), transesophageal echocardiography revealed ...19592229782
the effect of methylxanthines on milk volume and composition, and growth of rat pups.a study was conducted to investigate the effect of differential dose levels of methylxanthines on lactational performance, with respect to milk volume and composition and pup growth. the methylxanthines; caffeine, theophylline and theobromine, were administered via drinking water in the proportions occurring in tea, at a dose of 50, 1 and 2 mg/kg body-weight respectively to wistar albino rats throughout pregnancy and for up to the 14th day of lactation. a fourth group received a mixture of all t ...19902223739
the effect of methylxanthines on milk volume and composition, and growth of rat pups.a study was conducted to investigate the effect of differential dose levels of methylxanthines on lactational performance, with respect to milk volume and composition and pup growth. the methylxanthines; caffeine, theophylline and theobromine, were administered via drinking water in the proportions occurring in tea, at a dose of 50, 1 and 2 mg/kg body-weight respectively to wistar albino rats throughout pregnancy and for up to the 14th day of lactation. a fourth group received a mixture of all t ...19902223739
the effect of abdominal surgery on the serum concentration of the tumour-associated antigen ca 125.the ca 125 assay is used to monitor the course of disease in women with adenocarcinoma of the genital tract. we measured serum ca 125 levels longitudinally in three different groups of patients who had normal serum ca 125 levels (less than or equal to 16 u/ml) before extensive intraperitoneal abdominal surgery (group 1, second-look laparotomy in 28 women with ovarian cancer; group 2, radical hysterectomy in 42 patients with cervical cancer; group 3, 13 men and one woman who had aortic surgery fo ...20072223686
the effect of abdominal surgery on the serum concentration of the tumour-associated antigen ca 125.the ca 125 assay is used to monitor the course of disease in women with adenocarcinoma of the genital tract. we measured serum ca 125 levels longitudinally in three different groups of patients who had normal serum ca 125 levels (less than or equal to 16 u/ml) before extensive intraperitoneal abdominal surgery (group 1, second-look laparotomy in 28 women with ovarian cancer; group 2, radical hysterectomy in 42 patients with cervical cancer; group 3, 13 men and one woman who had aortic surgery fo ...20072223686
radioimmunotargeting of human tumour cells in immunocompetent animals.a tumour model system is reported that for many purposes may be an alternative to xenografted nude mice. the model allows immunotargeting of human tumour cells in immunocompetent animals. the target cells are contained in i.p. diffusion chambers (dc) with micropore membrane walls that are permeable to molecules, including the cell specific monoclonal antibodies (moab), but impermeable to cells. thus, the tumour cells are protected from the host immunocompetent cells. in the work here presented t ...19902223574
radioimmunotargeting of human tumour cells in immunocompetent animals.a tumour model system is reported that for many purposes may be an alternative to xenografted nude mice. the model allows immunotargeting of human tumour cells in immunocompetent animals. the target cells are contained in i.p. diffusion chambers (dc) with micropore membrane walls that are permeable to molecules, including the cell specific monoclonal antibodies (moab), but impermeable to cells. thus, the tumour cells are protected from the host immunocompetent cells. in the work here presented t ...19902223574
non-hodgkin's lymphoma: a histopathologic and immunohistochemical study of 79 cases.recently immunophenotyping has become a valuable tool in the diagnostic workup of malignant lymphoma. we classified 79 consecutive cases of non-hodgkin's lymphoma experienced at our hospital during the last two years according to the working formulation and immunologically using mt1, uchl1 and mb2 monoclonal antibodies. the results of this study are as follows: 1) four cases (5.1%) were low grade, 54 cases (68.4%) were intermediate grade, and 21 cases (23.3%) were high grade. the most common sub ...20062219970
the effects of stress during the brain growth spurt. 19902206630
[doppler examination as an indication for surgical delivery. a case report].pathological alterations in foetoplacental circulation can lead to zero flow or even to reverse flow in the diastole. in these cases, a high fetal risk can be expected. based on our doppler measurements, we recommend by zero flow in the umbilical artery or foetal aorta, that the childbirth could be postponed under an observant attitude using intensive controls (ctg, foetal movements), but pregnancy has to be terminated immediately by caesarean section at the first sign of reverse flow.20062197168
gene-deleted ibrv marker vaccine. 19902175520
adrenal findings with cmv infection in aids. 19902168675
[2 cases of a combination of arterial and arteriovenous cerebellar aneurysms]. 20072168653
genetic controls of mitochondrial development and function. genetic analysis of subunits 6 and 9 of yeast ubiquinol-cytochrome c oxidoreductase complex. 19902168205
effects of intrastriatal hormones on the dorsal immobility response in male rats.previous research has shown that estradiol administered either peripherally or directly into the striatum potentiates the dorsal immobility response (dir) in ovariectomized female rats. male rats are even more responsive than females to intrastriatal estradiol, and furthermore respond to the effects of catecholestrogens while females do not. in order to determine whether the heightened effects of estrogens in males are due to conversion to catecholestrogens, castrated male rats were given bilate ...19902157227
effects of intrastriatal hormones on the dorsal immobility response in male rats.previous research has shown that estradiol administered either peripherally or directly into the striatum potentiates the dorsal immobility response (dir) in ovariectomized female rats. male rats are even more responsive than females to intrastriatal estradiol, and furthermore respond to the effects of catecholestrogens while females do not. in order to determine whether the heightened effects of estrogens in males are due to conversion to catecholestrogens, castrated male rats were given bilate ...19902157227
a short dna sequence from lambda phage inhibits protein synthesis in escherichia coli rap.the escherichia coli rap mutant inhibits vegetative growth of bacteriophage lambda. phage mutations termed bar, which overcome the rap defect, have been mapped to three genetic loci in the pl operon. plasmids with a lambda wild-type bar dna segment cloned downstream from an active promoter cannot be maintained in rap mutant bacteria. the viability of a rap mutant strain decreases rapidly after induction of transcription through bar regions present on plasmids. under these (restrictive) condition ...19902147720
preparation and characterization of anti-paroxetine antibodies.6-nitroparoxetine was synthesized and reduced to 6-aminoparoxetine. after coupling to glutaraldehyde at the 6-position and to bovine serum albumin, the resulting schiff's base was further reduced into an amino-derivative which served as the antigen. anti-paroxetine antibodies were raised against this antigen in rabbits and the anti-paroxetine igg purified by protein a affinity chromatography. the anti-paroxetine igg demonstrated high specificity towards paroxetine and 6-nitroparoxetine without s ...19902147049
quality of life measurement--breast cancer. 19982143942
interactions between estrogens, androgens, progestins, and glucocorticoids in zr-75-1 human breast cancer cells.the human breast cancer cell line zr-75-1 possesses androgen, estrogen, progesterone, and glucocorticoid receptors, thus offering a good model to study the specific role of each class of steroids in the control of breast cancer growth. although the stimulatory action of classical estrogens (e2 and estrone) is well known, we have found a potent mitogenic effect of the adrenal estrogen androst-5-ene-3 beta,17 beta-diol (delta 5-diol) at concentrations within the range of those found in the serum o ...19902142871
cell cycle kinetics of insect cell cultures compared to mammalian cell cultures.cell cycle kinetic of lepidopteran cell lines sf9 (spodoptera frugiperda) and izdmb0503 (mamestra brassicae) were investigated and compared to mammalian cell cycle distributions. the resting phase (g0) of mammalian cells is characterized by a 2c-dna content whereas g0-phase of insect cell lines is characterized by a 4c-dna content. flow cytometric data in combination with growth curves of partially synchronized and asynchronously growing cells proved the existence of this phenomenon. kinetics of ...19902142463
prevalence of psychiatric disorders in a mandatory screening program for infection with human immunodeficiency virus: a pilot study.ninety-five randomly selected human immunodeficiency virus (hiv)-seropositive air force personnel were psychiatrically examined during a routine medical evaluation. of the 95, 95% did not have acquired immunodeficiency syndrome and were largely asymptomatic; 61.1% had clinical axis i diagnoses, which included simple phobia, adjustment disorders, hypoactive sexual desire disorder, alcohol use disorder, major depression, and organic mental disorders; 30.5% had personality disorders. significantly ...19902106656
susceptibility to lysis of pulmonary alveolar macrophages by human lymphokine-activated killer cells.in this study we addressed the question of whether lymphokine-activated killer (lak) cells, besides killing neoplastic cells, may exert a certain degree of lysis on the normal counterpart; in particular we took into consideration the toxicity against pulmonary alveolar macrophages (pam). we demonstrated that human lak cells generated in vitro following incubation of peripheral blood mononuclear cells with recombinant interleukin 2 for 4 days were able to lyse normal pam in a 4-h 51cr release ass ...19902106387
transvaginal sonography in early pregnancy. 19632106242
dual functions of insect immunity proteins in defence and development. 20072100024
oxygen-transport fluid based on perfluorochemicals: effects on liver biochemistry.the effects of (1) i.v. injection of various perfluorochemical (pfc) emulsions, (2) different fractions of the non-ionic poloxamer surfactant, pluronic f-68, or (3) i.p. injection of component pfc oils have been studied separately in male and female rats. injection of 10 ml/kg body wt of either fluosol-da 20% (f-da) or a novel perfluorodecalin emulsion containing a c-16 oil additive in male rats increased liver weight up to 7 days later; no corresponding effect occurred in response to injection ...19902096632
[recurrent thromboembolism disclosing protein c deficiency. apropos of a case with familial investigation].every thromboembolic manifestation, especially in young subjects, calls for an aetiological study in which haemostasis is evaluated primarily with assays of physiological coagulation inhibitors: protein c, protein s and antithrombin iii. protein c deficiency is found in 6 to 7% of thromboembolic manifestations. we report the case of a 21-year old man who had phlebitis followed by pulmonary embolism without facilitating factors. protein c level was 50% of normal value (0.50 iu/ml). the patient re ...19902075365
the effects of oral contraceptives on well-being and sexuality.the extent to which the high discontinuation rate for oral contraceptives is due to adverse effects of mood, well-being and sexuality is explored, taking into account early studies on high dose combined and sequential pills, recent studies on low-dose combined and triphasics, experimental design factors, effects of ocs on free androgen levels, psychosocial factors and reasons for choosing or stopping pills, effects on depressive illness, premenstrual syndrome, sexuality, and possible mechanisms ...20072075004
[differential roentgenological diagnosis of injuries of the lower cervical vertebrae].on the basis of 14 experiments with simulation of the lower cervical vertebra dislocations on cadavers and human cervical vertebra blocks, combined with stage discography, the authors singled out 3 groups of +disk and ligament structure damages: damage of capsular--ligamentous apparatus of the rear support complex; damage of ligamentous--capsular apparatus and disk; damage of ligamentous-capsular apparatus, frontal longitudinal ligament and total rupture of a disk. differentiation is made accord ...19902074961
bullous pemphigoid antigen: cdna cloning, cellular expression, and evidence for polymorphism of the human gene.a human epidermal keratinocyte lambda gt11 recombinant cdna library was screened with a 0.45-kb cdna that was generated by polymerase chain reaction (pcr) amplification of a segment of human bullous pemphigoid (bp) antigen mrna. the screen yielded five clones, the largest one, pcbpa-4, being 2.3 kb in size. the pcbpa-4 cdna hybridized in northern analyses with an approximately 9-kb mrna from cultured keratinocytes, whereas no hybridization signal was detected with rna from human skin fibroblast, ...19912045679
an evaluation of waist to hip ratio measurement methods in relation to lipid and carbohydrate metabolism in men.the purpose of this study was to determine which method of measuring waist to hip ratio (whr) was the most effective in assessing decrements associated with an abdominal fat distribution in 46 non-obese, middle to older aged men (mean +/- s.e., age 52.8 +/- 0.88 years; body fat 19.7 +/- 0.72 percent). circumferences were obtained at the following sites and whr calculated (waist circumference/hip circumference): (1) minimal waist/maximal hip; (2) level of umbilicus/maximal hip; (3) level of umbil ...20072045211
characterization of refractory period extension by transcardiac shock.to better understand the refractory period extension (rpe) produced by transcardiac shocks and its possible role in defibrillation, we measured rpe under various experimental conditions.19912040057
coeliac disease. 20071976395
effects of beta-casomorphin derivatives on gastrointestinal transit in mice.some d-amino acid-substituted derivatives of beta-casomorphin (cm) were found to exhibit a special affinity to central opiate receptors. concerning their affinity to peripheral opiate receptors our knowledge is still limited. the results of our experiments indicate that cm derivatives interfere with peripheral opiate receptors and that there is a close connection with the affinity to different subtypes of this receptor.20071965564
differentiation of the chick embryo floor plate.in a number of species, the floor plate of the developing neural tube and spinal cord has been ascribed specialized functions associated with the patterning of neuronal differentiation. the differentiation of the floor plate itself is believed to be closely related to the presence of the underlying notochord. grafting experiments have previously shown that in the chick embryo an implanted segment of notochord is capable of inducing the adjacent host neural plate or neural tube to produce an addi ...20071952103
[microbiological care of ventilated intensive care patients. feasibility of diagnosis and therapy of pulmonary infection].pulmonary infections are the most life-threatening infections in mechanically ventilated patients. methods to avoid these infections by prophylactic systemic or local administration of antibiotics may promote resistance and selection of distinct groups of pathogens. in mechanically ventilated patients we studied the impact of early diagnosis and specific therapy on the prevention of pulmonary infections. due to the very short interval between colonization and infection, daily microscopic and mic ...19911952044
interpersonal aspects of the supervision of individual psychotherapy.both the pleasures and pains of psychotherapy supervision have been described for the three parties--resident, supervisor, and patient--involved in such work. although both positive and negative aspects have been included in order to be comprehensive, it is clear to those who have engaged in supervision for many years that the pleasures far outweigh the pains for those concerned. a variety of means of facilitating the growth and increasing the knowledge of student psychotherapists have been unde ...20071951784
effects of experimental hyper- and hypothyroidism on natural defense activities against lewis lung carcinoma and its spontaneous pulmonary metastases in c57bl/6 mice.the effects of expermentally induced hyper- and hypothyroidism on the growth and development of spontaneous pulmonary metastases of lewis lung carcinoma (3ll) cells were studied in a murine system. progression of 3ll tumors growing in mice was associated with significant reduction in the serum levels of t3 and t4. subcutaneous (s. c.) injections (3 times/week) of t3 resulted in a hyperthyroid state with elevated t3 and reduced t4, whereas treatment with t4 induced a hyperthyroid state with eleva ...19911948998
maternal hydration increases amniotic fluid index.although adequate amniotic fluid (af) volume is considered an important aspect of fetal well-being, the etiology of decreased af volume is not well understood. a randomized blinded trial was designed to examine our hypothesis that maternal hydration would increase the af index in women with low af indexes. women seen in our testing centers were randomized into control or hydration groups. the control group was instructed to drink their normal amount of fluid; the hydration group was instructed t ...20061945215
maternal hydration increases amniotic fluid index.although adequate amniotic fluid (af) volume is considered an important aspect of fetal well-being, the etiology of decreased af volume is not well understood. a randomized blinded trial was designed to examine our hypothesis that maternal hydration would increase the af index in women with low af indexes. women seen in our testing centers were randomized into control or hydration groups. the control group was instructed to drink their normal amount of fluid; the hydration group was instructed t ...20061945215
imaging of the temporomandibular joint in juvenile rheumatoid arthritis. 20071932822
a nonexponential, nonlogarithmic pharmacokinetic dosing method for gentamicin. 20071914430
relationship between severity and clinical importance of symptoms in osteoarthritis.seventeen patients with primary osteoarthritis of the knee were evaluated with respect to the severity and clinical importance of pain, stiffness and physical function during the conduct of a double-blind randomized controlled trial of flurbiprofen sr versus diclofenac sodium sr using the womac osteoarthritis index. mean importance scores were similar for items within the same dimension as well as between items in different dimensions. in general, low levels of correlation were noted between the ...20071914413
treatment of malignant leydig cell tumor.malignant leydig cell tumors (lct) are rare. only 32 cases of malignant lct (as evidenced by metastatic spread) were reported. generally metastatic spread occurs within 2 years of the primary lct, and the patient dies within 2 years of the discovery of metastatic disease. the tumor is highly resistant to both radiation and chemotherapy. it also has a great propensity for recurring after surgical resection. a case is reported of a patient whose metastatic disease occurred 8 years after his primar ...20071913469
prognostic value of rhesus blood groups in oral squamous cell carcinomas.in the current study of the prognosis of all patients (n equals 70) with squamous cell carcinomas (scc) of floor of mouth in norway during the period 1963 to 1972, the authors found that patients with rhesus (rh) (d)-negative blood group had significantly poorer prognosis (mean 5-year survival, 8%) than patients with rh (d)-positive blood group (5-year survival, 30%) (p equals 0.04). this extends the authors' previous observations in another group of oral cancer patients. the authors do not know ...19911913459
aerosol ventilation scintigraphy in the evaluation of bronchopleural fistula: a case report and literature review.radioaerosol scanning is simple to perform and is widely used in conjunction with perfusion imaging to detect pulmonary emboli. it may also be a valuable tool for the early diagnosis of postpneumonectomy bronchopleural fistula. the authors present an illustrative case in which radioactive aerosol imaging was used to confirm a bronchopleural fistula secondary to pneumonectomy for squamous cell carcinoma.20071913391
the case of a reluctant mule. 20071913381
assessment of congenital hip dislocation with real-time ultrasound: a pictorial essay.real-time ultrasound (us) is the imaging method of choice for diagnosis and follow-up of congenital dislocation of the infant hip (cdh). clinical aspects and the role of imaging are reviewed. technique and anatomy, both normal and abnormal, are illustrated, as well as, the use of sonography during treatment with pavlik harness and spica cast. correlation of ultrasound findings with clinical examination, other available imaging studies and long-term patient follow-up shows 100% sensitivity and 10 ...20071913315
effects of long-term inhalation of n-nitrosodimethylamine in rats.the toxicological evaluation and histopathological findings of a long-term inhalation study in progress with n-nitrosodimethylamine (ndma) are presented. exposure was to three concentrations of ndma: 0.04, 0.2 and 1.0 ppm (corresponding to 120, 600 and 3000 micrograms/m3). a significant reduction in median survival time (nine months) was seen in animals treated with the highest concentration of ndma. tumours occurred mainly in the nasal cavity, with the highest incidences in the groups receiving ...19911855872
relevance of n-nitrosamines to oesophageal cancer in china.oesophageal cancer occurs at a very high frequency in certain areas of china, especially in linxian county, henan province. previous studies suggested that n-nitroso compounds play a causative role. in order to study further the exposure of linxian inhabitants, the intake of n-nitrosamines in the diet was determined. the total daily intake of volatile nitrosamines and of n-nitroso-n-methylbenzylamine (nmbza) was higher in linxian than in two other counties. nmbza can induce cancer in animal and ...19911855832
major histocompatibility complex (mhc) class ii region in humans. 20071855818
plasminogen polymorphism in libyans: description of a new rare variant.the genetic polymorphism of human plasminogen (plg) was investigated in libyans using wide-scale ultrathin-layer polyacrylamide isoelectric focusing with subsequent immunoblotting. the 2 common alleles, plg*a and plg*b, and 4 previously reported rare ones, plg*a3, plg*m4, plg*b1 and plg*b2, were observed. in addition, a new intermediate rare allele designated plg*mtripoli (plg*mt) was encountered. the estimated allele frequencies for the genes plg*a, plg*b, plg*a3, plg*mt, plg*m4, plg*b1 and plg ...19911855784
clinical validation of a second-generation fructosamine assay.the serum fructosamine assay, used to monitor short-term clinical glycemic control, reportedly has several technical drawbacks. however, technical improvements have resulted in a new second-generation assay of fructosamine. we evaluated this second-generation assay (from roche diagnostics) in 529 nondiabetic and diabetic patients and found a highly significant correlation with results of the first-generation assay (r = 0.91, p less than 0.001). use of the second-generation assay with samples fro ...20071855298
miniature manipulator with microelectrode for chronic recording of single units from freely-moving animals.we report a simple recording and stimulating system, a miniature manipulator with a microelectrode (mmm) that can be mounted on animal's skull. the system consists of a miniature manipulator and a microelectrode which are used in one body. several mmms can be implanted simultaneously into the brain as the part of the manipulator is small. with this device, recording of single units from several different cortices is possible from awake and unrestricted animals.19911851979
interaction of guanylic acid with the mg(ii), ca(ii), sr(ii), and ba(ii) ions in the crystalline solid and aqueous solution: evidence for the ribose c2'-endo/anti and c3'-endo/anti conformational changes.the interaction of guanosine-5'-monophosphoric acid (h2-gmp) with the alkaline earth metal ions has been studied in aqueous solution at neutral ph. the crystalline salts of the type mg-gmp.5h2o, ca-gmp.6h2o, sr-gmp.7h2o, and ba-gmp.7h2o were isolated and characterized by fourier transform ir, 1h-nmr and x-ray powder diffraction measurements. two types of macrochelate complexes have been identified: (a) the direct metalbase and indirect metal-phosphate bindings (inner and outer sphere interaction ...20071851044
oral administration of ssg, a beta-glucan obtained from sclerotinia sclerotiorum, affects the function of peyer's patch cells.the effect of orally administered ssg, a beta-1,3-glucan obtained from the culture filtrate of a fungus, sclerotinia sclerotiorum ifo 9395, on the function of peyer's patch (pp) cells was investigated in comparison with that on spleen cells in mice. oral administration of ssg enhanced the proliferative response of pp cells to a t-cell mitogen, concanavalin a (con a), and a b-cell mitogen, lipopolysaccharide (lps), although the response of spleen cells was not affected. peyer's patch cells taken ...19911828793
isoproterenol selectively releases endogenous and [14c]-labelled taurine from a single cytosolic compartment in astroglial cells.taurine is stored in and released from astroglial cells. we have investigated whether taurine is stored in multiple subcellular compartments and whether taurine is released from a distinct pool. taurine compartmentation was examined by determining the subcellular distribution of labelled taurine and by comparing the specific radioactivities of taurine in cells with that of the taurine released into the superfusion medium during receptor stimulation. three observations indicate that taurine is fo ...20071828789
albumin excretion rate is not increased in atherosclerotic patients with peripheral vascular disease.in type i diabetic patients, microalbuminuria is considered predictive of nephropathy and has been found associated with an increased mobility and mortality for atherosclerosis. an association between microalbuminuria and atherosclerosis has been reported in non diabetic atherosclerotic patients with hypertension. the aim of this study is to evaluate whether albumin excretion rate (aer) is increased in a selected group of normotensive patients with documented peripheral atherosclerotic disease. ...20071821046
biting behavior of anopheles mosquitoes in costa marques, rondonia, brazil.mosquito collections were made in and near costa marques, rondonia, brazil, to determine anopheline anthropophilic/zoophilic behavior. collections from a non-illuminated, bovine-baited trap and indoor and outdoor human-bait collections were compared. anopheles darlingi and anopheles deaneorum were more anthropophilic than the other anophelines collected. the remainder of the anopheles species were collected much more frequently in bovine-baited traps than in human-bait collections. anopheles dar ...19911815282
[comparative study of culture media for isolating brucella ovis].for the isolation of brucella ovis, modified thayer-martin medium with the addition of 0.01 micrograms/ml of trimethoprim and 100 iu of nystatin (tmm) was compared with skirrow agar (sk). using viable counting technique, 11 strains were evaluated and the results were compared with those using columbia base agar with bovine blood 7% (cba). ninety-four semen samples of 33 rams from a flock with infection antecedents were cultured on the same media. growth of brucella ovis strains was similar in al ...19911815277
non-adrenergic, non-cholinergic neural activation stabilizes smooth-muscle tone independently of eicosanoid factors in guinea-pig isolated airways.1. we examined the effect of variations in resting smooth-muscle tone induced eicosanoid inhibitors on the direction and magnitude of the non-adrenergic, non-cholinergic (nanc) nervous response in guinea-pig isolated airways. 2. nanc responses (in the presence of 1 microm atropine, 10 microm guanethidine) to electrical field stimulation (1200 ma; 0.5 ms; 240 s; 3 hz) were studied in guinea-pig isolated airway preparations (n = 4-7) taken from the proximal trachea, the distal trachea and the main ...19911797314
non-adrenergic, non-cholinergic neural activation stabilizes smooth-muscle tone independently of eicosanoid factors in guinea-pig isolated airways.1. we examined the effect of variations in resting smooth-muscle tone induced eicosanoid inhibitors on the direction and magnitude of the non-adrenergic, non-cholinergic (nanc) nervous response in guinea-pig isolated airways. 2. nanc responses (in the presence of 1 microm atropine, 10 microm guanethidine) to electrical field stimulation (1200 ma; 0.5 ms; 240 s; 3 hz) were studied in guinea-pig isolated airway preparations (n = 4-7) taken from the proximal trachea, the distal trachea and the main ...19911797314
immobilisation of enzymes to nylon film. 20071783118
injury severity: better data through direct physician entry of anatomic injuries?the authors compared the injury diagnoses and injury severity scores (isss) generated by three data-collection and -coding methods, and examined the times needed and costs associated with the methods. one method involved direct electronic entry of injury data by a physician in the admitting area. codes, severity scores, and times and costs varied significantly with the different methods, thus suggesting a need for further study of the derivation of injury severity codes.20071770847
cyclic changes in amphibian egg microvilli occur during the division cycle: implication of mpf.the microvilli (mv) of pleurodeles (amphibian) eggs were examined following fertilization and compared with those of artificially activated eggs and enucleated eggs using scanning and transmission electron microscopy. the mv pattern in fertilized eggs was found to undergo a cyclic transformation during the course of the first few division cycles. similar changes also occurred in the mv of artificially activated eggs and enucleated eggs. the reorganization of the mv was sensitive to cycloheximide ...20061769344
the effect of age on motor neurone death following axotomy in the mouse.the ability of mouse motor neurones to survive axotomy during the first month of life was studied. the motor neurones that lie in the dorsolateral columns of spinal segments c7 and c8 and supply the flexor muscles of the forepaw were axotomized by cutting and removing part of the median and ulnar nerves above the elbow. the number and position of cell bodies with axons in these nerves were confirmed by retrograde labelling of the cut axons with horseradish peroxidase. the ability of these neuron ...19911769343
growth hormone prevents steroid-induced growth depression in health and uremia.treatment with supraphysiological doses of corticosteroids results in protein wasting and impairment of growth, whereas exogenous growth hormone (gh) causes anabolism and improvement of growth. we wanted to know whether the growth depressing effects of methylprednisolone (mp) are more expressed in an organism which is chronically diseased and whether these effects can be counterbalanced by concomitant treatment with recombinant human growth hormone (rhgh). mp in doses from 1 to 9 mg/kg/day cause ...19911762304
laryngectomy: the patient's view.the disabilities following laryngectomy are well recognized. the incidence of these disabilities and the acceptability of the surgery to the patients were assessed by a questionnaire method. sixty-five patients participated in the study. the incidence of disabilities are discussed. total laryngectomy was felt to be a worthwhile operation by most of the patients in the study despite the disabilities they experienced afterwards.20061761948
cyclic amp-induced slow inward current: its synaptic manifestation in aplysia neurons.three presynaptic neurons, monosynaptically connected to the medial cells of the pleural ganglion of aplysia californica and previously shown to elicit camp-mediated diminutions in k conductance in those cells (kehoe, 1985a, b), were shown to elicit still another slow synaptic current that resembles the camp-induced cationic current described in the preceding paper (kehoe, 1990). the synaptic current elicited by these so-called "blocking" neurons was compared, in hyperpolarized medial cells, wit ...20061698941
human prolactin gene expression. the use of an alternative noncoding exon in decidua and the im-9-p3 lymphoblast cell line.the prolactin (prl) gene is normally expressed in the anterior pituitary lactotrope and the decidualized stromal cell of the human endometrium. we have recently described the ectopic expression of the human prl gene in a b-lymphoblastoid cell line, im-9-p. the im-9-p and decidual prl mrnas are approximately 150 nucleotides longer than the pituitary transcript. the protein coding sequence of the im-9-p and decidual prl cdnas is identical to the pituitary prl message, and the 3'-untranslated regio ...19901697858
human prolactin gene expression. the use of an alternative noncoding exon in decidua and the im-9-p3 lymphoblast cell line.the prolactin (prl) gene is normally expressed in the anterior pituitary lactotrope and the decidualized stromal cell of the human endometrium. we have recently described the ectopic expression of the human prl gene in a b-lymphoblastoid cell line, im-9-p. the im-9-p and decidual prl mrnas are approximately 150 nucleotides longer than the pituitary transcript. the protein coding sequence of the im-9-p and decidual prl cdnas is identical to the pituitary prl message, and the 3'-untranslated regio ...19901697858
the dysmyelinating mouse mutations shiverer (shi) and myelin deficient (shimld).shiverer (shi/shi) is an autosomal recessive mouse mutation that produces a shivering phenotype in affected mice. a shivering gait can be seen from a few weeks after birth until their early death, which occurs between 50 and 100 days. the central nervous system of the mutant mouse is hypomyelinated but the peripheral nervous system appears normal. the myelin of the cns, wherever present, is not well compacted and lacks the major dense line. myelin basic protein (mbp), which is associated with th ...19901693848
expression and processing of the rooster protamine mrna.in situ hybridization in immature and mature testis sections shows that the rooster protamine mrna is transcribed in the post-meiotic stages of spermatogenesis. two distinct populations of rooster protamine mrna are expressed as determined by northern blot analysis. since there are two copies of the chicken protamine gene per haploid genome, the question was raised of whether the two mrna populations correspond to the two different genes or was a result of differential mrna processing. the fact ...19911664677
antagonism of the motor effects of cgrp and of capsaicin on the guinea pig ileum by human cgrp8-37. 19921637118
[counseling is a success--ann-christine starts a course on the climacteric now. interview by eva aldstedt]. 20061636293
[you can lose money when you get sick during the course]. 20061636284
[the human chorionic gonadotropin (hcg) receptor: a new class within the family of gtp protein coupled receptors. epitope mapping of receptor-bound agonistic and antagonistic forms of hcg].human chorionic gonadotropin (hcg) is a member of the glycoprotein hormone family. it is composed of an alpha and a beta subunit, the latter being closely homologous to that of human luteinizing hormone (hlh). hcg and hlh bind to the same receptor. the molecular mass of hcg is 38 kd, up to 30% of which is contributed by the carbohydrate moieties linked to each of the two subunits. structure-function relationship studies have indicated that both subunits interact with the receptor and that altoge ...19921636261
recurrent or aggressive bladder cancer. indications for adjuvant intravesical therapy.advances in understanding of the variables that adversely affect the prognosis of patients with superficial bladder cancer allow more accurate predictions of the aggressive biologic potential of tumors. intravesical therapy appears to be an effective and essential adjuvant in those patients with high-risk tumor variables. multiple risk factors related to the tumor, individual patient characteristics, and treatment modality must be evaluated. assignment of the relative importance of these risk fa ...20061636233
stroke risk from alcohol consumption using different control groups.our aim in this study was to investigate the relation between chronic alcohol consumption and stroke.20061636184
effects of norethisterone on pressor response to angiotensin ii in men.we examined the effects of norethisterone and/or mestranol on the pressor response to angiotensin ii in 20 healthy men.20061635747
the rat mast cell antigen ad1 (homologue to human cd63 or melanoma antigen me491) is expressed in other cells in culture.previously we reported that the mab ad1 recognized a heavily glycosylated 50- to 60-kda protein (ad1 ag) sterically close to the high-affinity ige receptor on rat basophilic leukemia (rbl-2h3) cells. the n-terminal amino acid sequence of the ad1 ag was nearly identical to that of human cd63 (melanoma-associated ag me491). in this study we cloned the cdna of ad1 ag from a rat basophilic leukemia 2h3 cdna library. an open reading frame of 238 amino acids was identified that contained the n-termina ...19921634775
[cryptococcosis in aids patients: a study of 19 cases].we discuss 19 cases of infection due to cryptococcus neoformans diagnosed in 438 aids patients admitted to our center (4%). fourteen of them showed meningitis confirmed by culture of c. neoformans in csf. clinical features were rather unspecific and disorders in csf parameters were non striking. the diagnostic techniques performed with best results were culture of c. neoformans and antigen determination, especially in serum. survival probability at one year was 75%. treatment response was good. ...19921626090
rubella. winter outbreak in the australian capital territory (act). 20061622773
cholelithiasis in patients treated with a very-low-calorie diet.one hundred seventy-nine obese patients (mean body mass index = 36.3) were retrospectively evaluated for the development of cholelithiasis associated with the use of a 2530-kj/d (605-kcal) very-low-calorie diet (vlcd). nine percent of patients had preexisting gallstones and 11% of patients developed gallstones either during or within 6 mo of completing the diet. six percent had subsequent cholecystectomy. ursodeoxycholic acid administered to one patient resulted in spontaneous stone dissolution ...20061615894
late onset familial hallervorden-spatz disease: mr findings in two sisters.two sisters affected by late onset hallervorden-spatz disease are described. in both patients, mr showed rings of decreased signal intensity surrounding hyperintense areas that gave a target-like appearance to the globi pallidi, a finding that corresponds with the known pathologic lesions in the disease. mr reflects the metabolic and anatomic evaluation of this disease.20061595483
food composition tables and food composition analysis in east europe. 20061589999
search for the optimal treatment of ovarian cancer: heavy metals, "belly baths," and ... yew trees. 20061569441
electrophysiologic basis of dynamic extensor splinting.the use of dynamic extension splinting in the rehabilitation of extensor tendon injuries is gaining interest because of its apparent ability to improve clinical results. with such splinting, the extensor musculature is theoretically quiescent during both active flexion and rubber band-mediated extension; the gliding produced thereby decreases adhesion formation. our initial intent was to perform electromyographic studies on volunteers in dynamic extension splinting to test this electrophysiologi ...20061564273
modulation of venular microvessel permeability by calcium influx into endothelial cells.it has been proposed that calcium ion influx into endothelial cells modulates the permeability of venular microvessels via a calcium-dependent contractile process. the results of recent investigations using permeabilized endothelial cell monolayers conform to this hypothesis by demonstrating a calcium-dependent interaction of endothelial actin and myosin during the retraction of adjacent endothelial cells exposed to inflammatory agents. little is known about the pathway for calcium influx into e ...19921563597
an autopsy case of renal cell carcinoma associated with extensive peliosis hepatis.an autopsy case of renal cell carcinoma with extensive peliosis hepatis is reported. the patient was a 34-year-old female, who had had a left nephrectomy for renal cell carcinoma but died of multiple metastases one year and 4 months after surgery, despite chemotherapy and interferon treatment. at autopsy, the liver was enlarged markedly with multiple metastatic nodules and the non-neoplastic hepatic parenchyma had a spongy appearance, due to diffusely scattered, blood-filled cystic lesions. hist ...20061557990
a portuguese/brazilian study of expressed emotion.expressed emotion is a measure of family interaction, widely used in studies around the world to predict relapse in severe psychiatric disorders. the instrument was originally developed in london. it depends on subtle vocal nuances emerging in the course of the camberwell family interview (cfi). the extent to which these can be picked up in different languages and different cultures is an interesting question. this paper presents the results of a study of ee from brazil. the two raters achieved ...20061557678
diagnosis of sickle cell disease in chronically transfused patients.standard electrophoretic methods for the diagnosis of hemoglobinopathies are confounded in individuals chronically transfused. we present the accurate diagnosis of sickle cell disease in two such transfused patients by the application of polymerase chain reaction technology to analyze patient's hemoglobin beta-chain genes directly.19921550267
peripartum cardiomyopathy with recovery in a patient with coincidental eisenmenger ventricular septal defect.severe pulmonary vascular disease was found during pregnancy in a 31 year old woman with a large ventricular septal defect. three months after delivery peripartum cardiomyopathy with severe biventricular failure developed. this was a chance association. recovery of ventricular function was slow but was complete two years later. there was no advance in the pulmonary vascular disease.20051540442
surgical decision analysis: esophagectomy/esophagogastrectomy with or without drainage?decision analysis was used to compare three management strategies for patients undergoing esophagogastrectomy for carcinoma of the esophagus or gastric cardia: drain all patients with either pyloromyotomy or pyloroplasty, drain no patient, or perform a test that stratifies patients into high-risk and low-risk groups for development of gastric outlet obstruction and drain the high-risk group. results indicate that a "drain all" approach is appropriate in clinical settings where the risk of gastri ...20061540069
mechanisms of flow-mediated signal transduction in endothelial cells: kinetics of atp surface concentrations.intracellular free calcium ([ca2+]i) was measured in single cells of a confluent endothelial monolayer subjected to defined flow. flow medium containing adenosine triphosphate (atp) was used to study the influence of flow forces upon agonist-response coupling as mediated via the p2y-purinoceptor. [ca2+]i responses were highly sensitive to the fluid motion at the cell surface; consecutive small increases of flow stimulated large [ca2+]i transients with the levels returning to baseline at the new ...19921489886
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