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[nursing--a woman's job!]. 20061489626
[ectotoxin-forming pyogenic staphylococcus aureus (s. aureus) as a cause of toxic shock syndrome (tss) in man].basing considerations on an extremely carefully examined case of toxic shock syndrome (tss), an analysis of this phenomenon is presented from the clinical and forensic points of view. tss is often associated with the term "tampon disease" but in the meantime it has turned out that it may also arise as a non-menstrual disorder, caused by local infections, for example after surgical interventions. the inevitable symptoms include: fever, exanthema, desquamation on the palms of the hands and soles o ...19921489323
acquisition of icu data: concepts and demands.as the issue of data overload is a problem in critical care today, it is of utmost importance to improve acquisition, storage, integration, and presentation of medical data, which appears only feasible with the help of bedside computers. the data originates from four major sources: (1) the bedside medical devices, (2) the local area network (lan) of the icu, (3) the hospital information system (his) and (4) manual input. all sources differ markedly in quality and quantity of data and in the dema ...19721484274
postoperative analgesia using a computerised infusion of alfentanil following aortic bifurcation graft surgery.a psion microcomputer controlled infusion system for alfentanil was assessed for the provision of post-operative analgesia in 14 patients who had undergone aortic bifurcation graft surgery. the system employed a pharmacokinetic model working in real time to deliver any selected target plasma concentration of alfentanil. the alfentanil infusion system was used for a mean time of 39 hours and for 96% of this time, patients were scored as having no pain or only mild pain. severe pain was recorded f ...19721484271
coordinated delivery of clinical care: the "re-integration" of the medical group practice.this paper suggests that for medical knowledge to be effective, it must be reliably translated into a series of synchronized activities, both clinical and operational. the goal of medical information science must be not only to identify the best course of care, but also through the use of systems for the ordering, scheduling, and deployment of staff and resources to assure that the planned course of care is reliably and efficiently delivered in actual practice settings. we present a brief histor ...20061482950
the development of a virtual database to provide on-line access to a large archive of clinical data.the archival database of the help hospital information system at lds hospital is too large to be stored on line. the archival data are important for clinical and research applications. demountable disk packs have been used to store the archival database. this method of storage has four significant disadvantages. a virtual database was developed to overcome the limitations of this data-management scheme. this virtual database enables the transparent use of appropriate low-cost network-based stora ...20061482943
konno procedure for congenital aortic stenosis with a single coronary artery from the left coronary sinus.a right coronary artery originating from the left coronary sinus and traversing anteriorly is thought to be one of the contraindications for a konno aortoventriculoplasty in congenital aortic stenosis because this procedure necessitates incision of the right ventricular outflow tract. the case of a 5-year-old girl with congenital aortic stenosis associated with a single coronary artery, successfully treated surgically by the konno procedure and right coronary artery reimplantation, is reported. ...20051482829
costs of pharmaceutical care: can the profession do anything?to review some of the factors that influence the cost of pharmaceuticals and the delivery of pharmaceutical care as well as some possible measures for decreasing these costs.20061482817
wire-guided endoscope passage. 19781473685
management strategies in tuberculous atlanto-axial dislocation.tuberculous atlanto-axial dislocation is an uncommon disease. five of six patients with tuberculous atlanto-axial dislocation were successfully managed using different strategies. the advantages and disadvantages of these different protocols and their appropriateness in a particular clinical situation are discussed.20061472318
chromosomal illegitimate recombination in mammalian cells is associated with intrinsically bent dna elements.illegitimate recombination is the most frequent mechanism for chromosomal rearrangements in mammalian cells, yet little is known about this process. most of the studies to date have looked at the sequences present at illegitimate junctions. these revealed the presence of recurrent dna motifs, none of which was consistently found. we have undertaken to determine if intrinsic dna structures such as bent dna elements could be a major determinant in chromosomal illegitimate recombination. using a tw ...20061464328
different activation domains stimulate transcription from remote ('enhancer') and proximal ('promoter') positions.we reported previously that the lymphocyte-derived octamer transcription factor 2a (oct-2a or otf-2a) activated both natural immunoglobulin promoters and synthetic promoters which contain the 'octamer' site, but was unable by itself to stimulate transcription from a remote enhancer position. here we examine a larger set of transcription factors with respect to their proximal versus remote activation. since a transcription factor may contain more than one activation domain, we have chosen to stud ...20061464321
importance of maintaining normal nasal function in the cleft palate patient.the external nose is a structure that provides prominence to the face. the internal nose is a paired nasal cavity that extends from the face to the pharynx. turbinates are major structures within the lateral walls of the nose. they perform the major functions of the nose that include respiration, humidification, temperature regulation, and filtration of the inspired air. conditions that obstruct the nose interfere with its optimal function. these range from acute or chronic infection to enlarged ...20061450189
design and inhibitory properties of synthetic bowman-birk loops.a cyclic tridecapeptide based on the sequence of an anti-tryptic loop of a bowman-birk inhibitor was synthesized, and demonstrated to be active as an inhibitor of trypsin. molecular modeling of this sequence suggested an improved sequence which demonstrated an order of magnitude improvement in the inhibitory constant.20061446974
long-term effects of exercise training and hyperalimentation in adult cystic fibrosis patients with severe pulmonary dysfunction. 20061428393
the regulation of endopeptidase-24.11 expression on human osteoblast-like cells in culture. 19921426566
midirs has set up the world's first computer midwifery data base. 20061403180
value of dundee coronary risk-disk. 20061392968
the spliceosome assembly pathway in mammalian extracts.a mammalian splicing commitment complex was functionally defined by using a template commitment assay. this complex was partially purified and shown to be a required intermediate for complex a formation. the productive formation of this commitment complex required both splice sites and the polypyrimidine tract. u1 small nuclear ribonucleoprotein (snrnp) was the only spliceosomal u snrnp required for this formation. a protein factor, very likely u2af, is probably involved in the formation of the ...20051383687
expression of her2/neu oncogene product p185 in correlation to clinicopathological and prognostic factors of gastric carcinoma.the expression of the her2/neu gene product p185 was retrospectively analyzed in 58 patients with gastric carcinoma. the results were correlated to various clinicopathological and prognostic factors. positive membrane staining for p185 could be detected in 38% of the patients (22/58). membrane staining was significantly greater in well and moderately differentiated tumors of the intestinal type when compared with poorly differentiated lesions and carcinomas of the diffuse type (p less than 0.01) ...20061352299
effects on body temperature in mice differentiate between dopamine d2 receptor agonists with high and low efficacies.the effects of different dopamine (da) d2 receptor agonists and the da d2 receptor antagonist, emonapride, on body temperature were studied in male mice. the aim of the study was to test whether da d2 receptor agonists ranging from full agonists to agonists with low efficacy could be differentiated by means of their effect on body temperature. talipexole induced a marked hypothermia (maximum decrease of 6.5 degrees c). apomorphine, quinelorane, (+)-4-propyl-9-hydroxy-naphtoxazine((+)-phno), and ...20061352251
pcr amplification of alleles at the dis80 locus: comparison of a finnish and a north american caucasian population sample, and forensic casework evaluation.allele and genotype frequencies for the highly polymorphic d1s80 locus were determined in a finnish population sample by using pcr followed by high-resolution page and silver staining, a procedure called the amplified-fragment-length polymorphism (amp-flp) technique. in 140 unrelated finnish individuals 15 alleles and 43 phenotypes were observed. the d1s80 locus demonstrated a heterozygosity of .77, and the power of discrimination was .92 in this sample representing a genetically isolated finnis ...19921347970
thymocytopoiesis is maintained by blood-borne precursors throughout postnatal life. a study in parabiotic mice.this study was designed to resolve the long standing controversy as to whether hematogenous precursors or resident intrathymic precursors maintain thymocytopoiesis in postnatal life. the kinetics of thymic chimerism was examined over a 21-wk period in 105 pairs of nonirradiated, thy-1-alloantigen-disparate, parabiotic b10.s mice. thymic chimerism reached reached maximum levels of 25% in the thy-1b and 16% in the thy-1a partners (mean 20.5% and 9.8%, respectively) 6 to 7 wk after parabiotic union ...20061347301
5-hydroxytryptamine receptor activity of the dopamine receptor agonist fenoldopam in canine tracheal smooth muscle.fenoldopam is a new vasodilator undergoing clinical trials for the treatment of hypertensive emergencies. its pharmacologic effects result from activation of vascular dopamine-1 receptors. in canine tracheal smooth muscle strips, fenoldopam caused a concentration- and calcium-dependent increase in tension, which was not antagonized by atropine, indomethacin or the dopamine-1 receptor antagonist, sch 23390. the ec50 (1.89 x 10(-6) m) exceeded that of serotonin or acetylcholine (8.38 x 10(-8) and ...19921346635
freeze-dried, cross-linked bovine type i collagen: analysis of properties.this study was undertaken to assess the physical and biological properties of freeze-dried cross-linked bovine type i collagen and to assess its potential for use in the guided tissue regeneration method of treatment of periodontal disease in human adult subjects. the modulus of elasticity, swelling ratio, and biodegradation rate were investigated. the collagen sponge was implanted subdermally into sprague-dawley rats and a histological study carried out at 2, 7, 21, 35, and 49 days post implant ...19921317425
the molecular mechanisms of cardiovascular and renal regulation by endothelin peptides.in summary, we have seen that endothelins are potent cardiovascular and renal regulatory peptides. cardiovascular regulation by endothelin requires complex spatial and temporal regulation of endothelin gene expression and the coordinated interplay of numerous signaling pathways. although the precise physiologic role for endothelin peptides in the cardiovascular and renal systems remains uncertain, two general models can be proposed, as follows. (1) endothelin appears to act as an autocrine or pa ...20051317401
maintenance therapy for cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome: foscarnet.the use of ganciclovir in the treatment of cytomegalovirus (cmv) retinitis in patients with acquired immunodeficiency syndrome (aids) is limited by marrow toxicity and by the development of resistance to this agent in cmv strains capable of causing progressive disease. foscarnet retains activity against ganciclovir-resistant cmv and has an adverse effect profile different from that of ganciclovir. preliminary data from studies conducted under the aids clinical trials group (actg) program indicat ...19921310573
expression and release of neuroregulators during development: monoamines and neuropeptides.the turnover of catecholamines (ca) was determined in the adrenal medulla and brain of rat fetuses and pups. in general we found a considerable increase soon after birth. the expression of mrna for ca-synthesizing enzymes was also considerably enhanced in the adrenals shortly after birth. furthermore, we demonstrated increased expression of neuropeptides after birth, increased synthesis of mrna encoding for neuropeptide y in the adrenals 24 h after birth; and considerable activation of the subst ...19921306802
a saved little heart--transposition of great arteries. 20051305656
st. john's medical college, bangalore. 20041304308
effect of tooth storage and cavity cleansing on cervical gap formation in class ii glass-ionomer/composite restorations.class ii cavities with the cervical margin just below the c-e junction and with two cervical retention grooves were prepared in intact human premolars, 31 cavities in teeth stored frozen and 29 cavities in teeth stored in 1% chloramine solution. the teeth from both storage conditions were assigned to two groups; in one group, the cavities were cleaned with a water spray, in the other group, with a cleaner containing 0.2% edta and 1% naf. all cavities were lined with vitrebond and restored with p ...19921303376
[the microbiological purification of industrial sulfur-containing sewage]. 19921303100
high-risk coronary angioplasty using percutaneous cardiopulmonary bypass support.balloon angioplasty has a high success rate but results in abrupt closure of the vessel in 2% to 6% of patients. this can lead to haemodynamic collapse and death, particularly if the patient has poor left ventricular function. in the event of abrupt closure of the coronary vessels, such patients may not survive long enough to undergo emergency bypass surgery. the prophylactic use of cardiopulmonary bypass to support patients at high-risk for angioplasty has been reported recently. we describe ou ...19981302578
appraisal of teachers in the faculty of veterinary science, university of liverpool.in 1988, the faculty of veterinary science, university of liverpool, introduced a system of teacher appraisal, following the report of a faculty working party. the system is designed to provide information which will help the personal development of teaching skills, and also to provide the information required by the university for promoting a lecturer to senior lecturer. it incorporates opinions from students, collected formally by means of questionnaires, and from personal peers chosen by the ...20051287953
[diabetes mellitus and pancreatic cancer: a case-control study in greater montreal, quebec, canada].in a population-based case-control study of dietary risk factors in french canadians in montreal, a total of 179 cases and 239 controls were interviewed between 1984 and 1988. it was found that the frequency of diabetes was almost three times higher in cases of pancreatic cancer (16%) than in the controls (6%), with an odds ratio (or) of 2.52 and a confidence interval (ci) of 1.04-6.11. fifty per cent of the pancreatic cancer cases had this disease before the cancer was diagnosed, compared with ...20051287744
changes in the spectrum of organisms causing respiratory tract infections: a review.over the last decade, the spectrum of organisms causing community-acquired acute lower respiratory tract infections has changed. streptococcus pneumoniae now causes approximately 30% of outpatient acute pneumonia-less than in former decades-whereas mycoplasma pneumoniae is found in both young and elderly patients. the enterobacteriaceae and staphylococcus aureus are now seen more frequently as respiratory tract pathogens in community-acquired pneumonia patients, and they are the major organisms ...19921287613
treatment of hypertension: the place of angiotensin-converting enzyme inhibitors in the nineties.the past decade has seen a shift in the strategy for hypertension treatment from stepped therapy--a highly structured monolithic series of steps--to recommendations for a more individualized selection of treatment. severe hypertension is a clear indicator to bypass traditional steps. demographic factors, such as age, gender, and race, are often cited, but have proved to be less helpful. concomitant medical conditions and problems are very common and are more often the crucial determinants in the ...20051283428
[polymorphism mi detected through the enzyme mspi in the study of congenital protein c deficiency].in order to find alternatives for the diagnosis of hereditary protein c (pc) deficiency, we have studied the diagnostic informativity of the restriction fragment length polymorphism (rflp) mi, located 7 kb upstream of the pc gene and detected with the restriction enzyme mspi.20051280311
body composition changes in women: effects of high and low exercise intensity.twenty college-age women participated in a ten-week physical training program involving two intensities of exercise. eleven women trained at a relatively high exercise intensity (hi) of 840 kgm/min while nine women trained at a low exercise intensity (li) of 420 kgm/min. body composition and residual lung volume changes were analyzed before and after the training program for both groups. there were no significant changes in body weight, body density, percent body fat, lean body weight and residu ...19941275684
long-chain (z)-9-alkenes are "psychedelics" to houseflies with regard to visually stimulated sex attraction and aggregation.three different tests on houseflies (musca domestica l.) revealed that both pheromone-free pseudoflies and male partner flies exhibit in the presence of mixtures of long-chain (z)-9-alkenes or pure (z)-9-tricosene enhanced releasing effects for two optical cues, which stimulate male houseflies to mating strikes and houseflies of both sexes to aggregation.19541269604
hydrocelectomy. evaluation of technique.a quick, simple, safe, and efficient means of hydrocelectomy is presented. the technique consists of extruding and fixing the testicle into a scrotal pouch. twenty hydroceles were repaired without complication or recurrence.20051265943
[report on the 17th convention of the vereinigung norddeutscher urologen, june 19-21, 1975, in malente]. 20051265938
[crystalline derivatives of d,l-gamma-carboxyglutamic acid-gamma, gamma'-di-t-butylesters]. 19921262225
electron microscopic evidence for a transsynaptic migration of tetanus toxin in spinal cord motoneurons: an autoradiographic and morphometric study.adult rats were injected intramuscularly (musculus deltoideus) with 125i-labeled tetanus toxin. first signs of tetanic rigidity became visible 12-13 h after injection: death occurred 1-2 h later. electron microscopic autoradiography of the ventrolateral spinal cord gray matter showed a large part of the radioactivity to be located in motoneurons (perikaryon, axon and dendrites) at 7 and 14 h after injection. a great majority of the rest of the label was found over synaptic terminals, most of the ...19761260442
[active eradication of streptococci in closed populations]. 20051251622
response of the human nasal mucous membrane to anti-human ige serum.the response of the nasal mucous membrane to anti-human ige serum was examined. the application of anti-ige sera to the nasal mucous membrane induced a nasal allergy-like symptom as well as nasal eosinophilia. this symptom was observed in the majority of nasal allergy cases and in some vasomotor rhinitis cases, while not in non-allergic normal persons. the nasal eosinophilia, however, increased not only in allergic patients, but in non-allergic persons in whom no nasal symptoms were induced. suc ...19751243638
transactional analysis for the physician: an introduction. 19951236336
[study of the sensitivity of halprowia (microorganisms of the olt group) isolated in joint pathology to antibiotics and sodium sulfapyridazine in in ovo experiments].sensitivity to antibiotics and sodium sulfapiridasin of the microorganisms of group olt, i. e. halprowia and chlamidia isolated from the joint fluid and synovial of the affected joints in patients with rheumatoid or non-specific infectious arthritis and raiter syndrome was studied in ovo. the data provided determination of the spectrum of their sensitivity to various drugs. the antibiotics of the tetracycline group, i. e. olemorphocycline, tetracycline and rondomycin were shown to have the highe ...19751225213
[prevention of cerebrovascular disorders with adrenergic substances].the author suggests an experimental model of cerebrovascular disorders of the neurogenic (adrenergic) nature following the administration of kcl into the lateral ventricles of the brain of cats or dogs. surgical desympathization considerably reduced the spasms of the cerebral vessels caused by the central effect of kcl. dihydroergotoxin, phenoxybenzamine, tropaphene, guanethidine and nialamide produced both the therapeutic and the prophylactic influence under the mentioned experimental disorders ...19751218262
in vitro neutrophil function and lysosomal enzyme levels in patients with sepsis. 19561216240
effects of pregnancy on bile acid metabolism. 19751216188
[the possibility of influenza virus reproduction in cultures of insect cells]. 19751214662
[effect of iaa on the content of rna in the cells and isolated nuclei of aspergillus oryzae].the content of rna in mycelium and isolated nuclei of aspergillus oryzae 3-9-15 was studied after its growth during two days on the modified capek medium containing 0.01 and 10 mg% of iaa. a direct correlation has been established between the extracellular concentration of iaa and its content in the mycelium and isolated nuclei of the fungus. the stimulating effect of the extracellular iaa on the content of rna in the isolated nuclei was optimal after one hour of incubation in the capek medium c ...19751214614
[variety of effects of vitamins on yeast cells in aerobic conditions].the effect of thiamine and biotin on the processes of cell division, assimilation of glucose, and accumulation of the biomass and nitrogen in the cells was studied with the candida yeast. the action of the vitamins depended on the source of nitrogen. in some strains, asparagine can substitute for biotin. biotin has different effect on the production of gamma-aminobutyric acid in candida pulcherrima, c. guilliermondii. c. tropicalis k3-10. high concentrations of arginine were found in c. guillie ...19751214604
[varicocele and male sterility]. 19651206792
[auto-immune interstitial cystitis]. 19651206791
a volumetric assessment of pollen levels in the air of ann arbor, michigan. 20051196148
furanoid fatty acids from fish lipids.fatty acids, recently reported as constituents of certain fish lipids, were identified to be derivatives of furan (furanoid fish fatty acids). 12,15-epoxy-13,14-dimethyleicosa-12,14-dienoic acid is predominant among the furan acids and is associated with bis-homologs in regard to chain length. monomethyl acids, such as 12,15-epoxy-13-methyleicosa-12,14-dienoic, are present in appreciable amounts. the structures were concluded from oxidative degradations, from mass spectrometry of methyl esters o ...20051196019
overview: nutrition and cancer. 19691187565
phosphatidyl choline: donor of 18-carbon unsaturated fatty acids for glycerolipid biosynthesis.kinetics of radiocarbon inforporation into the phyosphatidyl choline of pumpkin leaf fed 1(-14)c-acetate at low light intensity were strongly suggestive of lipid bound fatty acids acting as substrates for desaturase enzymes. after pulse labeling in direct sunlight with the same precursor, phosphatidyl choline and phosphatidyl glycerol contained up to 90% of total glycerolipid radiocarbon at the shortest sampling times. subsequent loss of radiocarbon from phyosphatidyl choline and a corresponding ...19791186446
[clinico-laboratory observations of patients with brucellosis]. 19781186061
problems associated with study of cell-mediated immunity to human tumors by microcytotoxicity assays. 19751185800
purine n-oxides. lxii. 2,4-dioxopyrido(2,3-d)pyrimidine n-oxides. 19701185329
direct dehydrogenation of aporphine alkaloids. 19701185328
[digitalization for acute myocardial infarction: haemodynamic changes in patients with heart failure at rest (author's transl)].haemodynamic changes after intravenous administration of 0.4 mg beta-methyldigoxin or 0.4 mg digoxin daily were measured on the first to fourth day in 42 patients in heart failure after onset of transmural myocardial infarction. regular reduction in filling pressure and increased stroke volume while arterial blood pressure remained unaltered pointed to improved contractility. digitalization in the first few days after infarction achieved sustained tendency towards improved haemodynamics. it is c ...20051183355
psychiatric morbidity in a sample of a london coroner's open verdicts.one hundred and thirty-four deaths recorded as open verdicts in the inner west london coroner's district during 1969 and 1970 have been surveyed for evidence of mental illness. for 110 (82 per cent) of these deaths the probable verdicts were suicide or accident and they were reclassified as undetermined deaths. of these deaths 73 per cent were diagnosed as mentally ill, 54 per cent were receiving medical treatment for psychological symptoms before death, 42 per cent had a history of psychiatric ...20051182365
results of orbital ultrasonography in 200 clinical cases. 19731177891
job involvement and satisfaction as related to mental health and personal time devoted to work. 20051176425
failure to consult specialist. 20051173090
part ii: the photic environment of clear tropical seas during the day. 20051166605
ultrastructure of rectum epithelium in isopoda (crustacea). 19811163151
[10 suggestions in hyposensitization]. 19811162675
[accidents as a function of the development of transport facilities. selected problems of medical assessment of someone's fitness to be a driver]. 19801161596
[recurrent idiopathic atrioventricular block (apropos of a case of 22 years development)]. 19791161469
[oxyphedrine: its positive inotropic action in normal subjects and in patients with myocardial infarct]. 19791161166
glucose-6-phosphate dehydrogenase (g-6-pd) deficiency in the newborn. 19821158512
[chronic peritoneal dialysis]. 19821158281
the cape town obstetric flying squad.the number and nature of the calls received by the cape town flying squad service during 1972 are compared with those received from 1954 to 1960. a threefold increase in the total number of calls received per year is related to a fall from 74% to 30% in calls connected with postpartum complications. reasons for these changes are suggested.19831154169
studies on etiology of essential hypertension. hemodynamics, water-sodium balance and response to pressor substances during long-term sodium restriction and after spontaneous blood pressure fall--.ci, tpri, pv, ecfv, nae, pra and a pressor response to na and at was measured before and after 1) sodium restriction and 2) spontaneous blood pressure fall (spontaneous fall) in the patients with essential hypertension and the following results were obtained. 1) ci did not change during sodium restriction and increased after spontaneous fall. tpri was reduced and the degree of this reduction was positively correlated with that of blood pressure reduction under these two conditions. 2) sodium res ...19831152191
impact of a retention program for disadvantaged medical students upon the medical school community. 19831152008
effects of afferent volleys from the limbs on the discharge patterns of interpositus neurones in cats anaesthetized with alpha-chloralose.1. in cats anaesthetized with alpha-chloralose, micro-electrodes have been used to record the discharge patterns of single neurones in the region of the nucleus interpositus. 2. almost all cells tested could be antidromically invaded following electrical stimulation of the contralateral red nucleus, showing that they were cerebellar efferent neurones. 3. a little over half of the interpositus neurones were spontaneously active, usually at rates of less than 20 impulses/sec. 4. about 40% of the c ...19751151794
effect of 3-(p-trifluoromethylphenoxy). n. n. methyl-3-phenylpropylamine on the depletion of brain serotonin by 4-chloroamphetamine.3-(p-trifluoromethylphenoxy)-n-methyl-3-phenylpropylamine (lilly 110140), when injected into rats at i.p. doses of 1 to 10 mg/kg, prevented the lowering of brain serotonin by 4-chloroamphetamine. the duration of 110140 action was very long, significant antagonism of 4-chloroamphetamine action being apparent still at 48 hours after a single dose of 10 mg/kg of 110140. the n,n-dimethyl tertiary amine derivative was as effective as 110140 itself in antagonizing serotonin depletion by 4-chloroamphet ...19751151729
bacteremia in febrile children under 2 years of age: results of cultures of blood of 600 consecutive febrile children seen in a "walk-in" clinic. 19751151561
the renal lesion of the laurence-moon-biedl syndrome.in nine children with the laurence-moon-biedl syndrome a high incidence of nephropathy was documented. renal involvement was noted in seven patients before or simultaneously with the diagnosis of lmbs. five have uremia and two have died. all patients had an abnormal urogrum. the spectrum of renal lesions ranged from mesangial tissue proliferation to glomerular clerosis, interstitial scarring, and medullary and cortical cyst formation. a relationship between the lesions seen in the lmbs and those ...19911151560
[surgical pulmonary stenosis used as an experimental model]. 19751149992
rapid analysis of the central nervous system stimulants, amphetamines, via gas chromatography-mass spectrometry: rapid acylation in the presence of a mercury catalyst.a simple, direct, instantaneous, and quantitative acetylating procedure for amphetamines has been developed. the method uses trifluoroacetic anhydride in the presence of mercuric trifluoroacetate as a catalyst. the product was characterized by a gas chromatography-mass spectrometry system. the salient features of this technique are: (a) rapidity of analysis; (b) no previous cleanup to remove adulterants; and (c) detection of amphetamines at the picomole level. we have routinely applied this tech ...20051149413
effect of lidocaine and quinidine on steady-state characteristics and recovery kinetics of (dv/dt)max in guinea pig ventricular myocardium.we studied the effects of quinidine and lidocaine on the steady-state relationship between membrane potential and the maximum rate of rise of the action potential, (dv/dt)max, and on the recovery kinetics of (dv/dt)max in guinea pig papillary muscles. the steady-state relationships were determined in fibers stimulated at 0.2/sec and depolarized with kcl. recovery kinetics were determined at various resting membrane potentials by assessing (dv/dt)max in progressively earlier premature action pote ...19751149184
inhibition and recovery of dna synthesis in host tissues and sensitive and resistant b16 melanoma after 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea, a predictor of therapeutic efficacy.single doses of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea caused transient suppression of [3h]thymidine incorporation into dna in bone marrow and gastrointestinal mucosa and more prolonged inhibition of such incorporation in b16 melanoma. a single dose of 1-(2-chloroethyl) -3- (trans-4-methylcyclohexyl) -1-nitro-sourea, 16 mg/kg, doubled the mean life-span after treatment of c57bl times dba/2f1 male mice bearing 12-day-old b16 melanomas. subsequent doses timed to minimize toxi ...19881149044
preliminary experience with 15 (s) 15-methyl prostaglandin f2 alpha for midtrimester abortion.twenty-six women received intramuscular or intra-amniotic 15 (s) 15-methyl prostaglandin f2 alpha to induce midtrimester abortion. the median initial injection-abortion interval was 10 hours and 25 minutes. the advantages of intramuscular analogue are somnolence and reduced discomfort during labor. disadvantages include severe gastrointestinal toxicity in the majority of patients and symptoms of acute respiratory distress in two patients.19861146878
effectiveness of the nitroblue tetrazolium test in demonstrating reduced bactericidal activity of polymorphonuclear neutrophils in schistosomal hepatosplenomegaly and ascites.the nitroblue tetrazolium (nbt) test was carried out on blood from ten normal individuals and 20 schistosomal patients, ten of whom had hepatosplenomegaly and ten hepatosplenomegaly and ascites. the test revealed defective neutrophils in patients who had hepatosplenomegaly accompained by ascites. the phagocytic and bactericidal effects from five of each of the two groups of patients; results substantiated tose obtained by the nbt screening test. the nbt screening test thus proved useful in detec ...19861146763
the concentration of ketone bodies, free fatty acids, and glycerol in the blood of obese perons after injection of insulin and glucose. studies before and during absolute fasting.the blood patterns of acetoacetate (aa), 3-hydroxybutyrate (3-hb), free fatty acids, and glycerol were registered after intravenous injection of insulin or glucose in seven obese persons. in each individual investigated the study with insulin was carried out first and that with glucose 2 days later. both sets of studies were repeated after 8 and 10 days of absolute fasting. in the studies both before and during fasting the concentration of aa and 3-hb in blood varied independently of lipolysis. ...19851145108
[experimental coronary artery obstruction and heart rate]. 19751144997
the availability to sheep of copper in pig-slurry and slurry-dressed herbage. 19751144412
proceedings: the effect of ketamine on renal blood-flow in greyhounds. 19751138789
[hemoptysis related to vascular, pulmonary, aortic and systemic causes]. 19941137301
relationship between static muscle strength and endurance: an interpretive review. 19901136926
[some factors determining the values of spirometric studies in an urban population]. 19881135046
editorial: cea-s-a more specific cea? 19931134520
a method for the separation of plasma amino acids by ion-exchange chromatography combined with a semi-automatic computation of plasma amino acid concentrations.a method is described for combining the separation of plasma amino acids on a single column amino acid analyzer with semi-automatic computation of the plasma amino acid concentrations. the system used for the quantitation of the amino acids consists of an integrator with a teletype printer fitted with a puncher, and a table calculator with a punch reader and a converter. by using this system, the total time required for the calculation of the molar plasma concentration of 30 amino acids from one ...19921133138
[nucleotides, coenzymes and indirect glycolysis metabolites in newborn infants' erythrocytes in a case of 13th pair trisomy with 13/13 translocation]. 19751132763
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