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cellular factors. immunologic tolerance: irradiation and bone marrow transplantation in induction of canine allogeneic unresponsiveness. 197717203
the use of behavioral checklists to assess physical examination skills. 199917754
[study of the function of the tubular acidification in 30 cases of cacchi-ricci disease]. 199918000
[bronchodilator therapy of asthma]. 200018798
bone erosions associated with intracranial arteriovenous malformation. 199619392
[experience with treating patients with a hypothalamic snydrome and neurasthenia by electrophoresis of a mixture of ganglioblockaders]. 199819904
antipsychotic drugs--an update. 199723420
compartmentalization of cyclic nucleotide-mediated hormone action. 199925610
[histamine h2 receptor antagonists in gastroduodenal pathology]. 200130144
oxygen metabolism by the anaerobic bacterium veillonella alcalescens. 197831846
carbodiimide-binding protein of h+-translocating atpase and inhibition of h+ conduction by dicyclohexylcarbodiimide.h+-translocating atpase, which catalyzes atp synthesis in biomembranes, is composed of a head piece (f1) and a membrane moiety (f0). using highly-purified f0 from a thermophilic bacterium ps3 (tf0), the following results were obtained. 1. inhibition by n,n'-dicyclohexylcarbodiimide (dccd) of h+ conduction through tf0 followed pseudo-first-order kinetics. the second-order rate constant for inhibitor-enzyme interaction was 5 times 10(3) m(-1)-min(-1). 2. h+ conductivity blocked by dccd was proport ...200033978
[angiographic aspects of hydatid cyst of the liver]. 199834857
[acid-base equilibrium in mother and fetus during labor and the resistance of newborn calves].investigated were a total of 59 cows presenting normal processes, of giving birth as well as dystocia, the time of delivery lasting 2, 10, 24, and 36 hours. seventeen cows with dystocia were treated intravenously with 500 cm3 of a 4 per cent solution of sodium bicarbonate and 40 g glucose. it was found that the changes in the ph values, alkali reserves, glycogen, and the peroxydase activity of the neutrophiles in the mothers and fetuses were dependent on the duration of parturition. cases of dif ...197834922
[the place of dobutamine in cardiovascular distress. mediterranean meeting in anesthesia and intensive care. round table discussion, nice 23 and 24 june 1978]. 199835057
tardive dyskinesia--reversible and persistent.twenty-one hospitalized patients over 50 years of age who had tardive dyskinesia were studied for 13 months. after withdrawal of neuroleptics and antidepressants for three months, dyskinetic symptoms abated in 12 patients and persisted in nine. discriminant function analysis showed that the persistent and reversible dyskinesia groups could be clearly separated and that the best discriminator was the number of drug-free intervals. the persistent dyskinesia group had had significantly longer neuro ...199835116
serum estrone, estradiol and estriol concentrations during oral hormone therapy after oophorectomy.serum estrone, estradiol and estriol concentrations during estradiolvalerate-norgestrel therapy for women who have undergone oophorectomy were studied. the patients in one group received 1 mg of estradiolvalerate in the morning and 2 mg of estriolsuccinate in the evening. the estrone and estradiol concentrations of the first and fifth day were at roughly the same level and the treatment caused no estrogen cumulation. the estriol concentrations on the fifth day were distinctly higher than on the ...200135403
hypnotic efficacy of temazepam: a long-term sleep laboratory evaluation.1 temazepam was evaluated in a strictly defined insomniac patient population under sleep laboratory conditions. two protocols were used: a short-term (26-night) and a long-term (54-night) protocol evaluated the efficacy of the drug administered at night at 15 mg (short-term study) and 30 mg (long-term study), respectively. 2 temazepam seemed to be both safe and effective at doses of 15 and 30 mg with up to 5 weeks of ingestion. 3 suppression of slow wave sleep was observed at the high dose, but ...199541543
filling defect in the urinary bladder. 199345865
[primary radiotherapeutic eutic results of uterine carcinoma in the years 1960 to 1968].a report is given of 448 cases of corpus carcinoma, treated by primary radiotherapy in the i-st gynecological university hospital in the years 1960 to 1968. the 5-years-healing rate in this period was 50.4 percent. it is emphasized that the cases represent a negative selection, as only inbetween the ages of 61 and 90 years. two women died primarily from pulmonary embolism (0.4 percent). in two patients a rectovaginal fistula developed. the increasing number of patients with diabetes mellitus (23 ...199249095
24-hour control of intragastric acidity by cimetidine in duodenal-ulcer patients.the effects of two dose regimens of cimetidine on 24 h intragastric acidity were investigated in six patients with duodenal ulcer. they received placebo capsules on the first day and cimetidine on the second day. cimetidine 0-8 g/day decreased 24 h mean h+ activity by 55% but 1-6 g/day decreased it by 67%, the difference being due to a greater nocturnal decrease in the high-dose group. intragastric ph remained below 2-0 for much of the treatment day but similar values were found in four post-vag ...199053554
[skin disease in cattle, caused by dermatophilus congolensis]. 197553909
streptococcal m protein extracted by nonionic detergent. i. properties of the antiphagocytic and type-specific molecules.group a streptococcal m protein was extracted with nonionic detergent and subjected to a number of physical, chemical, and immunological tests. m protein thus extracted was composed of multiple protein bands, ranging from 35,000 down to 6,000 daltons, all having type-specific precipitating activity. the anti-phagocytic proteins, however, were limited to three molecular species having mol wt of 28,000, 31,000, and 35,000 daltons, and could be separated from those proteins that had only type speci ...197658958
[surgery in an african hospital]. 200059009
science and art in preparing tissues embedded in plastic for light microscopy, with special reference to glycol methacrylate, glass knives and simple stains.plastic embedding preserves tissue structure much more faithfully than does paraffin. acrylic polymerization is innocuous to dye-binding groups in sections. the water solubility of glycol methacrylate monomer and the hydrophilic properties of the polymer allow for convenience in dehydration and for versatility in staining sections. five years of experience with glycol methacrylate (gma) embedding for light microscopy is summarized. methods for purifying gma monomer are cited. procedures for fixi ...199959421
[microinterferometric demonstration of sulfhydryl groups with 1-(4-chlormercuri-phenylazo)-beta-naphtol]. 197559491
treatment of today's scabies and pediculosis. 200159822
altered vitamin-d metabolism in pregnancy.low levels of plasma-25-hydroxy-vitamin-d (25-ohd) (less than 16 nmol/1) were found in 33% of a group of pregnant women studied in south london. non-white women in the last 10 weeks of pregnancy had significantly reduced levels compared with non-pregnant controls (p less than 0.02). plasma-25-ohd was unrelated to dietary vitamin-d intake, age, parity, social class, plasma-calcium, and plasma-albumin. reduction of plasma-25-ohd could contribute to the fall in plasma-calcium during pregnancy, and ...200164751
[palliative methods permitting oral feeding in patients with carcinoma of the esophagus (author's transl)].405 patient with carcinoma of the esophagus were operated on the unit from 1st january 1972 to 15th february 1977. among these 405 patients, 55 underwent prolonged esophageal intubation and 24 a palliative operation. we considered successively the various methods of prolonged intubation and the various types of palliative operation possible. at the end of this study, it appears that palliative surgery for carcinoma of the esophagus owing to the severity of the operation and the high post-operati ...199984816
plasma steroid and protein hormone concentrations in patients with benign prostatic hypertrophy and in normal men.serum levels of testosterone, fsh, lh and prolactin were measured by ria in patients with bph (benign prostatic hypertrophy) and in control men. the testosterone concentrations in the bph group were significantly lower than that of the control group. serum concentrations of fsh, lh, prolactin and estradiol, did not differ significantly in the 2 groups.199989045
antimicrobial susceptibility of vibrio cholerae from zaire and rwanda. 197990940
applied teaching concepts of animated motion slides in otolaryngology.motion is an essential part of otolaryngologic function, and an understanding of concepts of motion is critical in teaching otolaryngology. standard movie projection devices have intrinsic defects, such as considerable expense to make, complexity of operation, and a lack of flexibility. slide projection transparencies (2x2) offer instructional flexibility but could not be used to project motion until recently. using applications of gelatin films of images with polarizing light, we have been able ...199991151
cell-free synthesis and segregation of beta 2-microglobulin.beta2-microglobulin has been synthesized in vitro by using a rabbit reticulocyte lysate system and mrna from the mouse tumor cell line el4. the molecule is synthesized as a precursor with an nh2-terminal extension of 19 amino acids: ser-x-ser-val-x-leu-val-phe-leu-val-leu-val-ser-leu-x-gly-leu-tyr-x. the processing and segregation of this peripheral membrane protein are directly comparable to those of secretory proteins and integral membrane proteins: addition of dog pancreas microsomal membrane ...197991168
high prevalences of hla-b15 and hla-dw6 in patients with cryptogenic fibrosing alveolitis. 199991222
the zinc-iodide-osmium technique in studies of the neurosecretory system in rats. 197991310
[basic and clinical studies on serum alpha-fetoprotein by radioimmunoassay (author's transl)]. 199991460
the murine kupffer cell. i. characterization of the cell serving accessory function in antigen-specific t cell proliferation.murine kupffer cells, the tissue macrophages of the liver, were isolated by collagenase digestion, differential sedimentation over metrizamide, and glass adherence. the resultant cell population was more than 86% phagocytic, and 95% of cells stained positively for alpha-naphthyl butyrate esterase activity. the cells also had cell surface receptors for complement (c) and the fc portion of igg. in addition, a large proportion of kupffer cells was shown to bear ia antigens: about half of the cells ...197991637
an erythrocyte membrane-protein anomaly in march haemoglobinuria.in three patients with march haemoglobinuria a well-defined protein abnormality has been revealed by high-resolution sodium-dodecyl-sulphate/polyacrylamide-gel electrophoresis.200091785
male fertility after successful chemotherapy for lymphoblastic leukaemia. 200091850
distinction between endocervical and endometrial adenocarcinoma with immunoperoxidase staining of carcinoembryonic antigen in routine histological tissue specimens.the differential diagnosis of endocervical and endometrial adenocarcinomas can be improved by the demonstration of carcinoembryonic antigen (cea) in tissue by means of immunoperoxidase staining. tissue from 131 (80%) of 163 patients with endocervical adenocarcinoma but only 11 (8%) of 137 patients with endometrial adenocarcinoma was cea-positive. the commonest exceptions were endocervical mesonephroid adenocarcinomas (which were cea-negative) and endometrial adenosquamous carcinomas (which were ...200091890
intravenous immunoglobulin. 200091896
[orthosympathetic stimulation after hypercapnia in the rat].inhalation of a gas mixture : co2, 25% -- o2, 37.5% -- n2, 37.5%, provokes regularly in the light anaesthetized rat, an increase of catecholaminemia of central origin, associated with systemic arterial hypertension.197992225
[current modifications in lipoprotein staining method on acetate gel cellulose].some modification are proposed to standardize better the staining technique of lipoprotein fractions. these modifications facilitate greatly the procedure originally reported by colfs and verheyden.200092322
evidence for reappearance of trypanosoma brucei variable antigen types in relapse populations.seven out of 11 bovines infected with different clones of trypanosoma brucei showed 2 peaks of antibody activity against the infecting clone within 7 weeks, as measured by immunofluorescence, radioimmunoassay, and neutralization of infectivity tests. using other clones from an unrelated stock, antibodies to these clones were not detectable, indicating that the antibodies produced were specific to the infecting organisms. these results suggest that there was a reappearance or increase in numbers ...197992560
the accessibility of antigenic determinants of ribosomal protein s4 in situ.antibodies to escherichia coli ribosomal protein s4 react with s4 in subribosomal particles, eg, the complex of 16s rna with s4, s7, s8, s15, s16, s17, and s19 and the ri reconstitution intermediate, but they do not react with intact 30s subunits. antibodies were isolated by three different methods from antisera obtained during the immunization of eight rabbits. some of these antibody preparations, which contained contaminant antibodies directed against other ribosomal proteins, reacted with sub ...197992615
nocturnal hypoglycaemia and haemoglobin a1. 200192646
aberrant form of hymenolepis nana: possible opportunistic infection in immunosuppressed patients. 197992715
the carbohydrate content of apolipoprotein e from human very low density lipoproteins. 197992742
[effect of sympathetic nerve stimulation on the microvascular permeability for proteins and lipoproteins]. 197992794
immunological heterogeneity of the subunits of limulus polyhemus haemocyanin [proceedings]. 200192962
collagen in idiopathic pulmonary fibrosis. 200193187
delayed hypersensitivity to chlamydia trachomatis: cause of chronic prostatitis. 197993221
management of complications associated with lathe-cut soft contact lenses.at the present time, nine lathe-cut lenses are fda approved and commercially available in the united states. complications of lathe-cut soft contact lenses cover a wide spectrum of problems. five significant complications of lathe-cut lenses and their prevention and therapeutic management are discussed.200193259
calcium-dependent increase in adenosine 3',5'-monophosphate and induction of the acrosome reaction in guinea pig spermatozoa.experiments were designed to determine the interrelationship between cyclic amp and ca(2+) during the processes of sperm capacitation and the acrosome reaction. in minimal culture media containing pyruvate and lactate as substrates, guinea pig spermatozoa required a minimum of 1.0-1.5 hr to capacitate in the presence of 1.7 mm ca(2+) and a minimum of 0.5-1.0 hr to capacitate in the absence of added ca(2+). sperm cyclic amp concentrations were increased by as much as 30-fold within 0.5 min after ...197993280
[recent acquisitions concerning the relationships between vasoactive amines and delayed hypersensitivity]. 200193298
a method for the differentiation of t and b lymphocytes and monocytes migrating under agarose.this report describes alterations in the agarose lymphocyte migration technique which resulted in satisfactory differentiation of t and b lymphocytes and monocytes which have migrated as a monolayer for 1-3 days. the wright-giemsa staining used in the original method did not permit identification of individual migrating cell types. the most important modifications were changing from a plastic to a glass migration surface, and significantly reducing the overlying thickness of agarose which permit ...200193323
development assessment: the children's assessment team, f.m.c. 199993474
reverse transcriptase-associated rnase h. part iv. pyrophosphate does not inhibit rnase h activity of amv dna polymerase. 197993479
sickle cell trait and diabetic retinopathy.the presence of sickle cell trait and the prevalence and severity of retinopathy were assessed in 124 negro diabetics. sickle cell trait had no adverse effect on diabetic retinopathy.199993492
the fine specificity of regulatory t cells. iv. idiotypic complementarity and antigen-bridging interactions in the anti-lysozyme response.the hen egg-white lysozyme (hel)-specific b cells which are activated in response to hel share a cross-reactive idiotype as well as submolecular specificity. helper t cells of two different specificities are implicated in their optimal activation, one recognizing the idiotype and the other, an epitope on the hel molecule opposite to the one recognized by b cells. thus, efficient t-b collaboration involves both idiotypic complementary and antigen bridging.197993548
[purification and characterization of the free secretory piece of human colostrum (author's transl)].the free secretory piece is isolated from human colostrum by gel filtration and ion-exchange chromatography in high yield (200 mg/l colostrum). deae-cellulose chromatography separates the free secretory piece in two fractions which are electrophoretically distinct, but otherwise have the same characteristics, like molecular weight, antigenic determinants, n-terminal sequence, peptide map and amino acid composition. it was therefore concluded that the protein part of the secretory piece is homoge ...197993565
chlorpyrifos and 3,5,6,-trichloro-2-pyridinol: residues in the body tissues of cattle wearing chlorpyrifos-impregnated plastic ear tags. 197993609
substance p as neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation. 197993706
preferential replication of murine xenotropic type-c virus in human lymphosarcoma-derived cell lines.murine xenotropic virus, designated 698/x, was recovered by implantation of human lymphosarcoma-derived cells u-698m into nude mice of giovanella's colony. the budded and extracellular particles revealed typical type-c morphology, the latter possessing reverse transcriptase (rt) activity and exhibiting a buoyant density 1.17 g/ml in sucrose gradient. in competitive radioimmunoassay using iodinated p30 of rauscher mulv, the 698x viral concentrate and cell extracts of both implanted lymphosarcoma ...197993707
16, 16 dimethyl prostaglandin e2 reduces histamine release from the stomach and protects the gastric mucosal barrier altered by ethanol in neutral solution.damage to the gastric mucosal barrier results in histamine release from intramucosal stores. previous reports have shown that 16, 16 dimethyl prostaglandin e2 (dm pge2) protects the stomach from injury by various damaging agents in either acidic or neutral solution. furthermore histamine released in response to a damaging drug in an acidic medium was reduced by dm pge2. using the heidenhain pouch dog preparation, the present study examined the action of dm pge2 on ethanol-induced barrier breakin ...197993761
has myelin basic protein received a fair trial in the treatment of multiple sclerosis?autosensitization to some central nervous system antigen still remains one of the best hypotheses for the continuing pathogenesis of multiple sclerosis (ms). enough is now known about the cause, pathogenesis, and treatment of experimental allergic encephalomyelitis (eae) to test this hypothesis. reports of therapeutic failure of the encephalitogen myelin basic protein (bp) in the treatment of ms have their counterparts in similar therapeutic failures in eae. only highly inbred strain 13 guinea p ...197993873
solid phase radioimmunoassay for beta 2-microglobulin; a sensitive index for renal allograft evaluation. 199993992
photocoagulation treatment in diabetic retinopathy: a two-year pre- and five-year post-treatment study.a randomized controlled study covering a two-year pre-treatment and a five-year post-treatment period was performed in 42 patients with diabetic retinopathy given photocoagulation treatment in one eye. patients with progressive diabetic retinopathy of equal intensity in both eyes were selected from a single diabetes department. the course of diabetic retinopathy was assessed by ophthalmoscopy and composite fundus photographs as well as fluorescence angiography. in the first two-year post-treatme ...199994008
[histological and histochemical studies of the gastric mucosa of the mouse under normal conditions and following various treatments]. 197994241
[effects and adverse effects of colloid-containing solutions]. 200094260
characterization of the coronary vasodilator and hemodynamic actions of monensin, a carboxylic ionophore.the effects of monensin on coronary blood flow (cbf) and other hemodynamic parameters were studied in anesthetized dogs. a dose-response relationship was established, and it was found that the lowest doses of monensin (5-25 micrograms/kg) produced a dose-dependent increase (3-5x) in cbf with a concomitant decrease in total peripheral resistance (tpr). pretreatment with diphenhydramine, atropine, indomethacin, or propranolol resulted in no reduction in peak increase in cbf or in the duration of r ...197994374
influence of atropine on spontaneous or catecholamine-induced arrhythmias after experimental infarction in the dog.the effects of atropine on ventricular tachyarrhythmias induced by ligature of the anterior descending coronary artery were studied in conscious dogs. on the first day after surgery, animals received a mixture of quinidine and phenytoin orally in order to partially correct rhythm disturbances on the second day. the same animals were used on the third and fourth days after occlusion, when spontaneous regression of arrhythmias was occurring. atropine (0.2 mg/kg i.v.) or methscopolamine (0.2 mg/kg ...197994403
[recurrent jaundice in the course of natural and iatrogenic estrogen metabolism disorders].the authors report about a woman who had several recurrences of jaundice between 1974 and 1977. jaundice was connected with pregnancy and administration of female steroid hormones. (authors' modified)200094437
[prognostic value of alpha-foetoprotein in fulminant hepatitis (author's transl)].serum concentrations of alpha-foetoprotein (afp) were measured sequentially by radioimmunoassay in 32 patients with fulminant hepatitis and coma, 22 of whom died. levels were significantly elevated in 100% of patients who survived and in 7 out of 22 patients (38.5%) who died (p = less than 0.005). in the survivors the rise of afp levels was found early after the development of coma and subsequently in all serum samples obtained during acute phase of illness. in 2 of 7 fatal cases who had raised ...197994446
neovasculogenesis. triggering factors and possible mechanisms.the possible regulating mechanism(s) of neovascularization are discussed. experimental data supporting the view that ocular neovascularization might be triggered by a fundamental metabolic mechanism are presented. based on his own data and scattered evidence from the literature, the author suggests a model for a possible regulating mechanism of the neovascular process in which the prostaglandins fulfill the role of neovascular mediating substances. preliminary results demonstrating that indometh ...197994468
dependence of macromolecular composition and morphology of streptomyces hygroscopicus on specific growth rate.the dependence of macromolecular composition and morphology of streptomyces hygroscopicus on specific growth rate micron was investigated. the percentage of dna on dry weight (%dna) is constant, % protein is also nearly independent of micron whereas %rna rises considerably with increasing micron, regarding mycelia grown in glucose-limited and ammonium-limited continuous cultures as well as in discontinuous cultures with various carbon sources. it is probable that the overall synthesis of dna, rn ...197994484
the role of antigen-specific t cell factors in the immune response. 197994504
factors involved in the age-dependent resistance of mice infected with low-virulence mouse hepatitis virus.four-week-old weanling mice survived, whereas 1-week-old suckling mice died, after intraperitoneal inoculation of mouse hepatitis virus, mhv-s strain. the factors involved in this difference in susceptibility were studied. after virus inoculation, differences in virus growth in the liver and spleen were observed, which correlated with the susceptibility of animals to the virus. interferon, detected at an early stage of infection, was considerably lower in suckling mice than in weanling mice. tit ...197994538
effects of prazosin in the control of blood pressure in hypertensive dialysis patients.twenty-two chronic hemodialysis patients with hypertension were treated with prazosin. eight patients had volume-responsive hypertension, 11 volume-indpendent, and 3 high-renin hypertension. blood pressure fell in all volume-responsive patients from a predialysis level of 175 +/- 5/100 +/- 3 to 148 +/- 4/75 +/- 3 mm hg (p less than 0.001) after 3 months of therapy. prazosin alone was effective in volume responsive patients at a dose of 5 +/- 1.0 mg daily. the blood pressure fell in volume-indpen ...200094639
[multilayer analytical film system and its use in clinical chemistry]. 200094719
correlation between hepatic transport of cholephilic organic anions and their effect on hepatic mitochondrial respiration.the maximum biliary excretion rate (tm) of some nonmetabolized organic anions was investigated in anaesthetized male rats and was found to increase in the following order: indocyanine green (icg), rose bengal (rb), bromsulphthalein (bsp; its conjugation with glutathione was prevented by diethyl maleate), bromcresol green (bcg), eosine (e), bsp-glutathione conjugate (bsp-gsh), iodoxamic acid (ia) and amaranth (a). the accumulation of icg, rb, bsp and bcg in liver was relatively high, whereas e, b ...197994737
the effects of metiamide and h1 receptor blocking agents on anaphylactic response in guinea-pigs.the effects of metiamide and of four h1 receptor blocking agents (mepyramine, promethazine, clemastine and ketotifene) on anaphylactic reaction were studied in the guinea-pig. the h1 blockers conferred partial protection which shows that with the experimental protocol utilized (challenge injection with high doses of antigen), histamine plays a lesser role than other mediators released or synthesized. metiamide (30.0 mg/kg i.v.) noticeably enhanced the increase in pulmonary resistance observed du ...197994763
[characteristics of human dental pulp cells in cell cultures].the generation time and the division rate were measured with routine methods of cell culturing. the conditions contributing to the stagnation of growth were examined; the synchrony of the growth process was investigated. the biochemical composition of the cells was assessed via colorimetry and then compared with other cell systems. the cell culture examined may be used to test capping materials; only cells up through the eighth generation however should be utilized.197994854
on the pharmacology of venous smooth muscle from dog and man.changes in tension of spiral strips from canine and human veins induced by various drugs are compared with results from the literature on human veins. the order of potencies of alpha-adrenoceptor stimulating amines (adrenaline greater than noradrenaline greater than dopamine greater than isoprenaline) is similar in human and canine veins. comparison of the affinities for alpha-adrenoceptors of pharmacologic drugs (thymoxamine, indoramine, clonidine, dihydroergotamine) suggest marked differences ...197994863
[prevention of cardiovascular complications in manifest arteriosclerosis by the use of micristine].a long-term clinical trial in micristin-treated patients suffering from organic arterial circulatory disturbances is reported. problems of therapy monitoring by determination of the asa level in plasma and of control of platelet aggregation are discussed. acute cardiovascular complications (myocardial infarction, stroke, acute vascular occlusion, amputation and angiographically demonstrated progression) were observed. the observation time did not suffice to establish statistically significant di ...200194872
pyrazolidine derivatives: a comparative study of their effects on platelet aggregation.quantitative studies were carried out of the in vitro and ex vivo effects of phenylbutazone and 3-oxoalkyl substituted diphenyldioxopyrazolidines (kebuzone, tribuzone, benzopyrazone) on platelet aggregation. the specified pyrazolidine derivatives exhibited in vitro inhibitory effects on secondary platelet aggregation (induced by adrenaline and collagen), commensurable with the effects of sulfinpyrazone. the ex vivo efficacy was markedly influenced by the height of the drug level in blood and by ...197994876
[tumor plasminogen activators and their clinical significance].by means of a radio-immunological method the amount of plasminogen activators released by tumours was determined. the concentrations of tumour plasminogen activators was considerably higher in the venous blood of ovarial tumours than in the peripheral blood. in the uterine fluid the uterus cavity the concentration of plasminogen activator was increased in cases with neoplastic endometrium compared to those with normal endometrium.200194895
staining with chromoxane cyanine r.since pearse in 1957 introduced chromoxane cyanine r as a dual nuclear and cytoplasmic stain there have appeared numerous procedures for use of this dye. these have differed widely, sharing in common mainly the implication that each is best. a defendable procedure has been developed on an experimental basis and is reported here. four stock solutions are needed: (1) a 0.2% solution of chromoxane cyanine r in 0.5% aqueous h2so4 (v/v); boil this solution for 5 min, (2) 10% fecl3 in 3% hcl, (3) 1% a ...197994954
the effect of cyclophosphamide on a secondary ocular immune response in rabbits.treatment of rabbits with immunosuppressive doses of cyclophosphamide during the primary response to intravitreally injected bovine gamma globulin did not prevent priming for a secondary response to the same antigen. high antibody titers were found in the aqueous humor and serum of most of the treated rabbits. ocular tissue plaque forming cell numbers were similar to those of the controls in many of the rabbits, and slightly lower in others. treatment with cyclophosphamide completely suppressed ...197994972
integrated care: the hospital-based hospice. 200195041
[so-called refractory hypoxemia: treatment with acexamic acid].acexamic acid is currently used to avoid pulmonary fibrosis in patients treated with bleomycim. it seems to be equally effective to prevent pulmonary fibrosis in adult respiratory distress syndrome. the complications of this therapy are hypercalcemia and hypernatremia.200195046
[hepatitis b virus during pregnancy and its consequences in perinatology]. 197995065
visualization of mitochondrial coupling factor f1(atpase) by freeze-drying.it is known that the negatively stained preparations of inner mitochondrial membrane display characteristic approximately 9 nm f1 (atpase) knobs projecting from the matrix surface. freeze-etch studies have reported the absence of such knobs from the "etched" surface of the inner mitochondrial membranes. we have demonstrated their presence on the surface of smp (submitochondrial particles) prepared by freeze-drying for transmission electron microscopy. this identification has been substantiated b ...197995168
subclassification of murine t cells by computerized microphotometric analysis.splenocytes separated by physical means and classified as t cells bay immunologic tests and computerized microphotometric analysis are differentiated into subgroups by analysis of the distribution patterns of feulgen-positive nuclear dna. in like fashion t cells obtained as purified preparations after separation on a nylon column, and accepted as t cells by micromorphometric analysis were subjected to further computerized morphometric analysis of nuclear dna to form subgroups of cells. in each c ...200195181
theoretical basis for interest in acetylprocainamide and clinical experiences with this new antiarrhythmic agent.in conclusion, it was the differential responses of slow and rapid acetylators to procainamide therapy that gave the initial clues that acetylprocainamide might be a safer drug than procainamide. so far, the experience with acetylprocainamide has been encouraging.200195247
determination of small differences in buoyant density of macromolecules by analytical density gradient equilibrium centrifugation.a sensitive method is proposed for the determination of small differences between the buoyant densities of different species of monodisperse macromolecules by analytical density gradient equilibrium centrifugation. the procedure involves the measurement at sedimentation equilibrium of the bandwidths of the concentration distribution of the separate macromolecules and of a mixture of the different species. the difference in buoyant densities can then be estimated from the difference between the b ...200195253
world veterinary manpower: comparative aspects.the number of veterinarians in relation to livestock units, human population, milk and meat production and gross national product for 93 countries is presented. the structure of veterinary manpower is discussed and information on veterinary involvement with companion animals and public health is given. for 23 countries representing all the continents, the number of livestock units, human population and gross national product per veterinary school are presented.197995360
radioimmunoassay for the detection of hbeag and anti-hbe.we describe a solid-phase radioimmunoassay, based on the "sandwich" principle, using anti-hbe1/anti-hbe2 containing igg precoated to polystirene beads as the solid-phase, and 125i-anti-hbe as labelled antibody for the detection of hbeag and a two steps competitive procedure for the detection of anti-hbe. comparison of titre obtained by id and ria or reference sera containing hbeag and anti-hbe revealed that ria is about 200 fold more sensitive than id in detecting both hbeag and anti-hbe. moreov ...200195390
dextran anaphylactoid reaction in sprague-dawley cfy rats.from a closed colony of randomly-bred sprague-dawley cfy rats about 23% failed to respond to intravenous dextran with the characteristic generalized anaphylactoid reaction, but still exhibited an inflammatory response when dextran was given into the foot pad. brother-sister mating of rats showing the most expressed generalized reaction (reactor rats) yielded good responder offsprings, while the non-reactors had descendants completely unresponsive to systemic dextran. brother-sister mating of sel ...197995467
[clinical evaluation of the use of prifinium bromide in urologic patients]. 200195506
[desoxyribonucleid and ribonucleid acids and 5-hydroxytriptamine in the endometrium of patients with bleedings from the uterus (author's transl)]. 200195556
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