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a patient with thrombotic thrombocytopenic purpura caused by capnocytophaga canimorsus septicemia. 199911856273
effects of instrumentation, irrigation and dressing with calcium hydroxide on infection in pulpless teeth with periapical bone lesions.the aim of this study was to evaluate the fate of microorganisms in root canals of teeth with infected pulps and periapical bone lesions with and without the use of calcium hydroxide medication.200211858203
[dog bite in a splenectomized patient].we present a case of capnocytophaga canimorsus fulminant infection linked to a dog bite in a splenectomized patient. capnocytophaga canimorsus is a gram-negative rod that typically causes septicaemia with disseminated intravascular coagulation in both immunocompromised and immunocompetent hosts. it is associated with high mortality. we also reviewed the literature and provide some recommendations on the management of bite wound as well as on both prevention and treatment of infection in asplenic ...200211899497
skin microflora and bacterial infections of the skin.the skin is a milieu for controlled bacterial growth. skin supports the growth of commensal bacteria, which protect the host from pathogenic bacteria. environmental and local factors, host immunity, and organism adherence and virulence are intricately related to cutaneous infection. resident gram-positive bacteria include staphylococcus, micrococcus, and corynebacterium sp. staphylococcus aureus and streptococcus pyogenes are notoriously pathogenic in the skin. in order for bacteria to be pathog ...200111924823
long-term follow-up of osseointegrated titanium implants using clinical, radiographic and microbiological parameters.the aim of this study was to longitudinally follow up osseointegrated titanium implants in partially dentate patients by clinical, radiographic and microbiological parameters in order to evaluate possible changes in the peri-implant health over time. fifteen individuals treated with titanium implants, ad modum brånemark, and followed for ten years were included in the study. before implant placement ten years previously, the individuals had been treated for advanced periodontal disease and there ...200211952732
brain abscess due to capnocytophaga species, actinomyces species, and streptococcus intermedius in a patient with cyanotic congenital heart disease. 200211957031
actinobacillus actinomycetemcomitans in a rural adult population in southern thailand.the prevalence of actinobacillus actinomycetemcomitans isolates was examined in a rural population of southern thailand. sixty individuals aged 30-39 and 50-59 years were randomly selected from a group of 363 persons, living in four villages, who had been clinically examined previously. a subgingival plaque sample was taken with a curette from the mesial aspect of the two upper and lower first molars. each sample was dispersed in 3.3 ml of vmga iii transport medium and spread onto trypticase soy ...200212030964
prevalent bacterial species and novel phylotypes in advanced noma lesions.the purpose of this study was to determine the bacterial diversity in advanced noma lesions using culture-independent molecular methods. 16s ribosomal dna bacterial genes from dna isolated from advanced noma lesions of four nigerian children were pcr amplified with universally conserved primers and spirochetal selective primers and cloned into escherichia coli. partial 16s rrna sequences of approximately 500 bases from 212 cloned inserts were used initially to determine species identity or close ...200212037085
proposed minimal standards for describing new taxa of the family flavobacteriaceae and emended description of the family.in this paper minimal standards for the description of new genera and cultivable species in the family flavobacteriaceae are proposed in accordance with recommendation 30b of the bacteriological code (1990 revision). in addition to specified phenotypic characteristics, the description of new species should be based on dna-dna hybridization data, and the placement of new taxa should be consistent with phylogenetic data derived from 16s rrna sequencing. an emended description of the family is also ...200212054224
[in vitro sensitivity of oral gram-negative bacteria to the bactericidal activity of defensins].oral gram-negative bacteria, including actinobacillus actinomycetemcomitans, porphyromonas gingivalis, capnocytophaga sputigena, provotella intermedius, provotella melaninogenicus, have been associated with destructive periodontal infection. an ultrasensitive antibacterial assay was applied to determine the sensitivity of a battery of oral gram-negative bacteria to the bactericidal effects of the isolated human neutrophil defensins (hnp) and two kinds of rabbit defensins np1 and np2. all species ...199812078176
[capnocytophaga spp. bacteremia in neutropenic patients]. 200212139833
electrocardiographic myocardial infarction pattern in overwhelming post-splenectomy sepsis due to capnocytophaga canimorsus. 200212162399
capnocytophaga canimorsus sepsis in an immune-competent patient: tiny dog, major sepsis. 200212164399
recent taxonomic changes and terminology update of clinically significant anaerobic gram-negative bacteria (excluding spirochetes).because of access to 16s rdna sequencing, changes in the taxonomy and nomenclature of anaerobic gram-negative bacteria have occurred lately. new genera and species have been described, and existing taxa have been reclassified. the present article compiles a list of clinically relevant anaerobes and provides synonyms as well as the old nomenclature used for these bacteria. although names and classifications of anaerobic bacteria are changing quickly, it is important to keep track of new bacterial ...200212173103
microbiological, immunological and genetic factors in family members with periodontitis as a manifestation of systemic disease, associated with hematological disorders.the microflora, immunological profiles of host defence functions, and human leukocyte antigen (hla) findings are reported for a mother, son and daughter who were diagnosed as having 'periodontitis as a manifestation of systemic diseases, associated with hematological disorders'. examinations were made of the bacterial flora from the periodontal pocket, neutrophil chemotaxis, neutrophil phagocytosis, and the genotypes (dqb1) and serotypes (dr locus) of hla class ii antigens. phenotypic analyses o ...200212200976
capnocytophaga canimorsus endophthalmitis following cataract surgery.an elderly man developed endophthalmitis 1 week after cataract extraction and lens implantation. intraocular samples were collected and the patient received intravitreal vanco-mycin and ceftazidime, and topical tobramycin. a gram stain of vitreous humour revealed spindle-shaped gram-negative bacilli. he was then given systemic clindamycin and topical ofloxacin. capnocytophaga canimorsus, a member of the oral flora of dogs and cats, was cultured after 3 days. the infection resolved leaving the pa ...200212213167
stress and the periodontal diseases: effects of catecholamines on the growth of periodontal bacteria in vitro.microorganisms possess the ability to recognize hormones within the host and utilize them to adapt to their surroundings. noradrenaline and adrenaline, which are released during human stress responses, may act as environmental cues to alter the growth of individual organisms within subgingival biofilms. the aims of this study were to modify, for anaerobic culture, existing methodology used in determining microorganism catecholamine responses and to investigate the growth responses to noradrenali ...200212354211
[bacteremia due to capnocytophaga sp. in two oncologic patients]. 200212392680
[meningitis due to capnocytophaga canimorsus following dog bite]. 200212436391
meningitis due to capnocytophaga canimorsus after receipt of a dog bite: case report and review of the literature.we describe a case of meningitis due to capnocytophaga canimorsus and review 18 cases with attention to risk factors, clinical features, diagnosis, treatment, and outcome. in most of the reported cases, contact with dogs and predisposing factors were found. clinical manifestations and the findings of examinations of cerebrospinal fluid specimens were similar to those of classic bacterial meningitis; however, the mortality rate for c. canimorsus meningitis very low when compared with the rate for ...200312539089
effects of selected immunouppressive drugs on prostaglandin release, protein synthesis and cell proliferation in human gingival fibroblasts and on the growth of plaque bacteria.immunosuppressants play an essential role in transplantation therapy. in view of the side effects, e.g. gingival overgrowth, the present in vitro study was performed in order to investigate the effect of selected immunosuppressants on metabolic activities of gingival fibroblasts. furthermore, the effect on the growth of six oral microorganisms was investigated.200312578751
[bacteremia due to capnocytophaga spp.: two cases]. 200312586027
capnocytophaga gingivalis bacteremia detected only on quantitative blood cultures in a child with leukemia.capnocytophaga species are inhabitants of the normal mouth flora. we describe the case of a 6-year-old-girl with leukemia and poor oral hygiene who developed bacteremia caused by capnocytophaga gingivalis. the organism was detected only on quantitative blood cultures.200312613461
capnocytophaga canimorsus meningitis in a newborn: an avoidable infection.capnocytophaga canimorsus causes dog-bite wound induced sepsis in adults, but infection may follow mucous membrane exposure. systemic infection in children is extremely rare. a neonate with frequent exposure to a family dog and no cutaneous infection developed c. canimorsus meningitis. suspicion of this pathogen requires laboratory consultation. parental counseling can limit the risk of pet acquired infections.200312613462
proteolytic and hydrolytic enzymes from putative periodontal pathogens: characterization, molecular genetics, effects on host defenses and tissues and detection in gingival crevice fluid. 200312656998
subgingival microflora and antibody responses against periodontal bacteria of young japanese patients with type 1 diabetes mellitus.periodontal disease is a complication of patients with type 1 diabetes mellitus (t1dm), although the mechanisms responsible for this relationship remain unclear. the aim of this study was to examine oral manifestations and the prevalence of periodontal pathogens from subgingival plaque samples and serum igg antibody levels against them in young japanese type 1 diabetic subjects. one hundred and seventeen japanese t1dm subjects (53 male, 64 female, mean age +/- sd, 16 +/- 6.5 years) participated ...200112666949
serum phenytoin concentration and igg antibody titre to periodontal bacteria in patients with phenytoin-induced gingival overgrowth.epileptic patients taking phenytoin with gingival-overgrowth and those without gingival-overgrowth were compared for daily drug dose, plasma total phenytoin concentration, plasma free-phenytoin concentration and serum igg antibody titre against 13 periodontal bacteria. significantly higher daily drug dose was noted in patients with gingival overgrowth (p < 0.05) when compared with those without overgrowth. in addition, both total and free forms of plasma phenytoin concentration were significantl ...200112666977
purpura fulminans associated with capnocytophaga canimorsus infection. 200312670324
microbiology of mandibular third molar pericoronitis: incidence of beta-lactamase-producing bacteria.the purpose of this study was to evaluate the predominant flora associated with pericoronitis in third molars and to investigate the presence of beta-lactamase-producing strains.200312789143
subgingival microbiota levels and their associations with periodontal status at the sampled sites in an adult sudanese population using miswak or toothbrush regularly.little information is available on the effect of miswak use on gingival microbiota. we assessed levels of 28 oral bacteria in subgingival plaque of adult sudanese miswak (n = 38) and toothbrush users (n = 36) age range 20-53 years (mean 34.6 years) to study associations between these bacteria, oral hygiene method, and periodontal status at the sampled sites. a pooled subgingival plaque sample from 6 probing sites of 1 selected tooth in each jaw was obtained from each subject. whole genomic dna p ...200312790510
microbiologic and radiographic analysis of ligature-induced peri-implantitis with different dental implant surfaces.the goal of this study was to evaluate microbiota and radiographic peri-implant bone loss associated with ligature-induced peri-implantitis.200312814313
antibacterial activity of medicinal plant extracts against periodontopathic bacteria.this study was performed to evaluate the antibacterial activity of althaea officinalis l. roots, arnica montana l. flowers, calendula officinalis l. flowers, hamamelis virginiana l. leaves, illicium verum hook. fruits and melissa officinalis l. leaves, against anaerobic and facultative aerobic periodontal bacteria: porphyromonas gingivalis, prevotella spp., fusobacterium nucleatum, capnocytophaga gingivalis, veilonella parvula, eikenella corrodens, peptostreptococcus micros and actinomyces odont ...200312820224
a series of infections due to capnocytophaga spp in immunosuppressed and immunocompetent patients.to investigate the epidemiology, microbiology and outcome of infections caused by capnocytophaga spp. at a single center.200312848750
coaggregation of streptococcus salivarius with periodontopathogens: evidence for involvement of fimbriae in the interaction with prevotella intermedia.streptococcus salivarius is divided into two serological subgroups that carry either fibrils or fimbriae. although fimbriae have been observed on up to 50% of s. salivarius strains in the human oral cavity, no function has yet been assigned to them. to determine whether s. salivarius fimbriae have a role in adhesion, we examined the ability of s. salivarius to coaggregate with selected microorganisms involved in periodontal diseases. our results show that s. salivarius coaggregated with fusobact ...200312930529
localized aggressive periodontitis in primary dentition: a case report.a 5-year-old japanese boy presented with persistent gingival inflammation and severe mobility of the right lower primary incisors. due to severe alveolar bone loss and a deep periodontal pocket (5 mm), the incisors were extracted at the second visit.200312931770
capnocytophaga sp. isolated from a cat with chronic sinusitis and rhinitis.a capnocytophaga sp. was inadvertently isolated from a cat with chronic sinusitis and rhinitis when cytopathic effects were observed in crandall-reese feline kidney cells that had been inoculated with oropharyngeal swab samples. although capnocytophaga spp. are of considerable zoonotic importance, their clinical relevance for dogs or cats has not been established. however, failure to do so may be attributed to the infrequent use of specialized isolation techniques that are required to grow capno ...200314605195
in vitro antibacterial effects of glycyrrhetinic acid on periodontopathogenic and capnophilic bacteria isolated from adult periodontitis. 200314616694
infective endocarditis due to capnocytophaga canimorsus.we report the case of a 41-year-old woman with severe mitral regurgitation due to infective endocarditis caused by a rare zoonotic microorganism (capnocytophaga canimorsus). she had had a rheumatic mitral endocarditis successfully treated with antibiotics when she was 13 years old. she arrived to our attention for a fever of unknown origin. she had been bitten by her dog and medicated the wound herself. about 2 weeks later she developed a fever with values up to 39.5 degrees c. blood cultures we ...200314664287
[capnocytophaga bacteriemia and pulmonary embolism]. 200314697095
mixed bacteremia with capnocytophaga sputigena and escherichia coli following bone marrow transplantation: case report and review. 200414712364
bacterial colonization during de novo plaque formation.to determine microbial changes that occur during plaque formation in a dentition free of gingival inflammation.200314761122
genetic analysis of an ambler class a extended-spectrum beta-lactamase from capnocytophaga ochracea.a beta-lactamase gene (cfxa3, 966 bp) was isolated from a beta-lactam-resistant capnocytophaga ochracea clinical isolate and amplified using primers from the cfxa gene of bacteroides vulgatus. the mics of third-generation cephalosporins were much higher than those of the transconjugant escherichia coli strain. the deduced protein sequence, by comparison with cfxa2 of prevotella intermedia, had a y239d substitution and possessed the characteristics of a class a, group 2e beta-lactamase.200414766881
gingival crevice microbiota from chinese patients with gingivitis or necrotizing ulcerative gingivitis.the objective of this study was to quantitatively compare the bacterial population structure in plaque from the gingival margin of two groups of 21 chinese patients with gingivitis or necrotizing ulcerative gingivitis (nug). subjects were recruited in four dental clinics in eastern china. samples were quantitatively assessed by immunofluorescence and fluorescent in situ hybridization for taxa known to be associated with periodontal diseases. the analyses showed that the fusiform taxa (fusobacter ...200414871191
capnocytophaga canimorsus endocarditis.capnocytophaga canimorsus is a fastidious, gram-negative rod that forms part of the normal oral flora of dogs and cats. known for its ability to cause fulminant sepsis following dog bites, particularly in asplenic patients or alcoholics, this bacterium is also an uncommon cause of endocarditis. this article reviews 12 cases of endocarditis caused by c. canimorsus. mean age of patients was 53 years, with 78% of cases occurring in males. overall, a history of dog-bite was documented in four cases ...200414970251
occurrence of periodontal bacteria in healthy children: a 2-year longitudinal study.to examine the occurrence of specific periodontal bacteria in children and adolescents.200314986909
[meningitis due to capnocytophaga canimorsus with misleading initial digestive symptom].we set out a case of capnocytophaga canimorsus septicemia complicated by a meningitis in a chronic alcoholic male pensioner. the capnocytophaga canimorsus bacterium contaminated the patient after his dog licked little varicose wounds. initial symptoms led to a digestive infectious syndrome. capnocytophaga canimorsus grows more slowly than usual bacteria and appeals to a bacteriological deductive reflection which is provided in this article for its identification in a general hospital. in order n ...200415047501
[analysis of oral microflora early colonized in infants].to observe the dynamic changes of oral microflora early colonized in infants.200415190795
capnocytophaga canimorsus sepsis with purpura fulminans and symmetrical gangrene following a dog bite in a shelter employee.the authors describe a fatal case of purpura fulminans with symmetrical peripheral gangrene and sepsis caused by capnocytophaga canimorsus in a 45-year-old, previously healthy woman who was bitten by a dog at an animal shelter where she was employed. absent in this patient were the usual risk factors, including immunosuppression, alcohol abuse, corticosteroid therapy, and splenectomy. the patient's presentation to the emergency room late in the course of the infection probably effected her death ...200415201655
[septic shock with purpura fulminans due to capnocytophaga canimorsus]. 200415207129
relationship between volatile sulphide compounds concentration and oral bacteria species detection in the elderly.to evaluate the relationship between oral bacteria species detection and volatile sulphide compounds (vsc) concentration in the elderly.200415218895
fibrinolytic therapy in capnocytophaga canimorsus sepsis after dog bite. 200415232682
cellulitis caused by capnocytophaga cynodegmi associated with etanercept treatment in a patient with rheumatoid arthritis. 200415278747
chemotaxis-guided movements in bacteria.motile bacteria often use sophisticated chemotaxis signaling systems to direct their movements. in general, bacterial chemotactic signal transduction pathways have three basic elements: (1) signal reception by bacterial chemoreceptors located on the membrane; (2) signal transduction to relay the signals from membrane receptors to the motor; and (3) signal adaptation to desensitize the initial signal input. the chemotaxis proteins involved in these signal transduction pathways have been identifie ...200415284186
beta-lactamase production and antimicrobial susceptibility of subgingival bacteria from refractory periodontitis.this study assessed the extent of beta-lactamase-producing bacteria in subgingival plaque samples obtained from 25 patients with refractory marginal periodontitis in the usa. beta-lactamase-positive isolates were characterized using commercial diagnostic kits and partial sequencing of the 16s rrna gene. the susceptibilities to different antimicrobial agents were tested and, in addition, the isolates were screened for the presence of extended spectrum beta-lactamases (esbls). beta-lactamase-produ ...200415327642
the first fatal case of capnocytophaga canimorsus sepsis caused by a cat scratch.a case is presented of fatal capnocytophaga canimorsus sepsis caused by a neglected cat scratch. although fatalities are known to occur as a result of sepsis caused by this organism, death following cat scratch transmission has not previously been reported. the case is important as it demonstrates how a seemingly innocuous injury can have devastating consequences that may have been prevented by simple first aid measures.200415457651
subgingival microbiota of chronic periodontitis subjects from different geographic locations.most clinical studies assume that the subgingival microbiota is similar from one geographic location to another. the purpose of the present investigation was to examine the composition of the subgingival microbiota in chronic periodontitis subjects from four countries.200415491316
rate of cultivable subgingival periodontopathogenic bacteria in chronic periodontitis.although microbiological studies have identified more than 400 bacterial species in periodontal pockets, only a limited number have been implicated as periodontal pathogens. the purpose of this study was to investigate the incidence of cultivable subgingival periodontopathogenic bacteria in chronic periodontitis. bacterial samples were collected with sterile paper points from the deepest periodontal pockets ((5 mm) of 203 patients: 92 males and 111 females, aged 35-55 years. the samples were cul ...200415508748
killing of periodontopathogenic bacteria by photodynamic therapy.the aim of this study was to evaluate a new approach for killing periodontopathogenic bacteria using photodynamic therapy (pdt).200415562911
capnocytophaga spp. brain abscess in an immunocompetent host: problems in antimicrobial chemotherapy and literature review.the fourth case report of a brain abscess due to the fastidious gram-negative organism capnocytophaga spp. is described and discussed on the grounds of clinical, microbiological, and therapeutic evidence. a probable origin from a cat bite and/or an underlying severe mandibulary granuloma is suspected. due to lack of clinical and neuroradiological response to neurosurgery and a combination of imipenem-amikacin-clindamycin-fluconazole, second-line empiric llnezolid treatment proved rapidly success ...200415565920
capnocytophaga bacteremia in a girl with relapsed acute lymphoblastic leukemia. 200415573857
[an unusual aetiology for septic shock: capnocytophaga canimorsus. is always dog man's best friend?].the mortality of overwhelming postsplenectomy infections (opsi) is significant (50 to 80 percent). capnocytophaga canimorsus belongs to the normal oral flora of dogs and cats. it is seldom responsible for human infections, but its prognosis is bad (about 30 percent of overall mortality), especially in asplenic patients. we report a case of a splenectomized patient who suffered from communal septic shock due to c. canimorsus septicaemia. the course of events was rapidly fatal. diagnosis and mode ...200415589360
[bite wound infections].the lifetime risk of experiencing a bite wound, human or animal, is approximately 50%, and bite wounds account for approximately 1% of all visits to emergency departments. the majority of bite wounds are inflicted by dogs and cats.200415608763
detection and characterization of beta-lactamase genes in subgingival bacteria from patients with refractory periodontitis.fifty-three beta-lactamase-producing strains of oral bacteria isolated from patients with refractory periodontitis in norway and usa were screened for the presence of the bla(tem), bla(shv), bla(oxa), bla(ampc), bla(cfxa), and bla(cepa/cbla) genes by the polymerase chain reaction (pcr). the pcr products were characterized by direct sequencing of the amplified dna. thirty-four of the 53 enzyme-producing strains (64%) were positive in one of the pcr assays. all beta-lactamase-producing prevotella ...200515621454
differences in the subgingival microbiota of swedish and usa subjects who were periodontally healthy or exhibited minimal periodontal disease.previous studies have shown differences in the mean proportions of subgingival species in samples from periodontitis subjects in different countries, which may relate to differences in diet, genetics, disease susceptibility and manifestation. the purpose of the present investigation was to determine whether there were differences in the subgingival microbiotas of swedish and american subjects who exhibited periodontal health or minimal periodontal disease.200515642056
[bite-associated bacterial wound infections in humans].bite wounds are common injuries that are often mistakenly considered innocuous by both patients and physicians. these wounds consist of laserations, evulsions, punctures, and scratches. while many of these wounds require minimal or no therapy, a significant number results in infections, which may even be life-threatening. the bacteria associated with bite-wound infections generally originate from the oropharyngeal flora of the biting animal. the clinical presentation and appropriate treatment of ...200415700676
isolation and characterization of aminopeptidase from capnocytophaga granulosa atcc 51502.there is evidence that enzymes from the genus capnocytophaga play a role in dental calculus formation. although most of the species in the genus produce aminopeptidases, there is a paucity of data on the purification and characterization of the enzyme, except in the case of capnocytophaga gingivalis. the aim of this study was to purify aminopeptidase from culture supernatant of capnocytophaga granulosa atcc 51502, a new species of the genus. purification was performed using ammonium sulfate frac ...200515720565
molecular identification of capnocytophaga spp. via 16s rrna pcr-restriction fragment length polymorphism analysis.capnocytophaga spp. have been implicated as putative periodontal pathogens associated with various periodontal diseases. although the genus is known to contain five human oral isolates, accurate identification to species level of these organisms recovered from subgingival plaque has been hampered by the lack of a reliable method. hence, most studies to date have reported these isolates as capnocytophaga spp. previous attempts at identification were based on biochemical tests; however, the result ...200515815015
effect of khat chewing on 14 selected periodontal bacteria in sub- and supragingival plaque of a young male population.the habit of chewing khat (catha edulis) for its amphetamine-like effects is highly prevalent in yemen and east africa, and has expanded to western countries. the purpose of this study was to estimate and compare the prevalence and levels of 14 periodontal bacteria in gingival plaque of khat chewers and khat nonchewers, as well as of khat chewing sides and khat nonchewing sides.200515836514
detection of heat shock proteins but not superantigen by isolated oral bacteria from patients with behcet's disease.we isolated bacteria from periodontal sites and mixed saliva in eight patients with behcet's disease and surveyed them to determine whether they produced heat shock proteins (hsps) and superantigen. cultivable bacterial compositions from periodontal sites and saliva were examined by anaerobic culture using blood agar plates. gram-negative anaerobic rods such as prevotella intermedia, fusobacterium nucleatum, and capnocytophaga species were predominant in the isolates from the subgingival plaque ...200515836518
prevalence of oropharyngeal beta-lactamase-producing capnocytophaga spp. in pediatric oncology patients over a ten-year period.the aim of this study was to evaluate the prevalence of beta-lactamase-producing capnocytophaga isolates in young children hospitalized in the pediatric oncology department of hôpital sud (rennes, france) over a ten-year period (1993-2002).200515882453
sepsis and meningitis due to capnocytophaga cynodegmi after splenectomy. 200515889384
molecular identification of an invasive gingival bacterial community.a woman with neutropenia developed gingival hyperplasia. biopsy showed invasion of gingival tissue with mats of filamentous organisms, and molecular analysis by polymerase chain reaction and fluorescence in situ hybridization revealed capnocytophaga sputigena, leptotrichia species, and fusobacterium nucleatum. oral bacterial flora may cause invasive gingival disease with hyperplasia in immunocompromised patients.200515937752
capnocytophaga spp. in periodontitis patients manifesting diabetes mellitus.the subgingival microflora in patients presenting concurrently with periodontitis and diabetes mellitus (dm) are poorly understood. while traditional putative periodontal pathogens are implicated, research involving other oral organisms; e.g., capnocytophaga spp., is lacking. these organisms produce a range of bacterial enzymes relevant to periodontal breakdown. it is inferred that periodontal bacteria acquire systemic access through the ulcerated periodontal pocket surface; conclusive evidence ...200515974842
prevalence of periodontopathic bacteria in aggressive periodontitis patients in a chilean population.actinobacillus actinomycetemcomitans is considered a major etiologic agent of aggressive periodontitis (agp). other periodontopathic bacteria such as porphyromonas gingivalis are also suspected of participating in aggressive periodontitis although the evidence to support this is controversial. the aim of the present study was to determine the prevalence of eight periodontopathic bacteria in chilean patients with agp.200515974855
periodontal disease and coronary heart disease: a reappraisal of the exposure.results from studies relating periodontal disease to cardiovascular disease have been mixed. residual confounding by smoking and use of clinical measures of periodontal disease rather than measures of infection have been 2 major criticisms. the aims of this study were to investigate relationships between prevalent coronary heart disease (chd) and 2 exposures, (1) clinical periodontal disease and (2) igg antibodies to 17 oral organisms, and to evaluate the role of smoking in these relationships.200515983248
the salivary microbiota as a diagnostic indicator of oral cancer: a descriptive, non-randomized study of cancer-free and oral squamous cell carcinoma subjects.the purpose of the present investigation was to determine if the salivary counts of 40 common oral bacteria in subjects with an oral squamous cell carcinoma (oscc) lesion would differ from those found in cancer-free (oscc-free) controls.200515987522
facial bite wounds: management update.bite wounds are frequently located on the face; injuries inflicted by dogs are most common, especially in children. bacteriology of infected dog and cat bite wounds includes pasteurella multocida, staphylococcus aureus, viridans streptococci, capnocytophaga canimorsus, and oral anaerobes. infected human bites yield a similar spectrum of bacteria except for pasteurellae and c. canimorsus; instead human bites are frequently complicated by eikenella corrodens. antibiotic therapy against these bacte ...200516053863
lower respiratory tract infection due to capnocytophaga cynodegmi in a cat with pulmonary carcinoma.a 10-year-old male castrated domestic shorthair cat was evaluated for coughing and lethargy. thoracic radiographs revealed a soft tissue lung mass and diffuse peribronchial infiltrates. bronchoscopy was performed and capnocytophaga cynodegmi was cultured from bilateral bronchoalveolar lavage samples. clinical signs and bacterial colonization resolved following treatment with enrofloxacin. a lung lobectomy was performed to remove the lung mass, which was diagnosed as pulmonary carcinoma. c cynode ...200516055008
identification of candidate periodontal pathogens and beneficial species by quantitative 16s clonal analysis.most studies of the bacterial etiology of periodontitis have used either culture-based or targeted dna approaches, and so it is likely that pathogens remain undiscovered. the purpose of this study was to use culture-independent, quantitative analysis of biofilms associated with chronic periodontitis and periodontal health to identify pathogens and beneficial species. samples from subjects with periodontitis and controls were analyzed using ribosomal 16s cloning and sequencing. several genera, ma ...200516081935
biochemical differentiation and comparison of desulfovibrio species and other phenotypically similar genera.seventeen human clinical isolates representing four species of desulfovibrio were characterized using 16s rrna gene sequences and tests for catalase, indole, nitrate, bile, urease, formate-fumarate stimulation, desulfoviridin, motility, and hydrogen sulfide production, plus susceptibility to antimicrobial agents. eighty additional strains representing 10 phenotypically similar genera (bilophila, selenomonas, capnocytophaga, campylobacter, bacteroides, sutterella, anaerobiospirillum, dialister, v ...200516081948
chromosome- and plasmid-encoded beta-lactamases in capnocytophaga spp.chromosome- and plasmid-encoded cfxa2 and cfxa3 beta-lactamases were detected in capnocytophaga spp. from oral sources in france, norway, and the united states. unidentified chromosome-encoded beta-lactamases were present in capnocytophaga sputigena. nucleotide sequence analysis of the cfxa3-encoding plasmid from c. ochracea revealed an unreported insertion sequence (iscoc1) upstream of the cfxa gene.200516127077
linezolid in the treatment of severe central nervous system infections resistant to recommended antimicrobial compounds.the progressive emergence of antimicrobial-resistant gram-positive cocci especially in the setting of surgery and intensive care, recommends particular attention in making sound therapeutic choices to overcome both microbial resistances and haemato-encephalic barriers to effective local drug penetration. as in other western countries, the occurrence of methicillin-resistant staphylococcus aureus is particularly high also in italy, especially when high-risk patients and/or settings are involved. ...200516220032
distribution of 10 periodontal bacteria in saliva samples from japanese children and their mothers.we analyzed the distribution of 10 periodontal bacteria species (porphyromonas gingivalis, tannerella forsythensis, prevotella intermedia, prevotella nigrescens, campylobacter rectus, eikenella corrodens, actinobacillus actinomycetemcomitans, capnocytophaga ochracea, capnocytophaga sputigena, and treponema denticola) in children, and then compared their distribution in those children and their mothers, with special attention given to three of the species known as the red complex (p. gingivalis, ...200616269128
epiglottitis and necrotizing fasciitis: a life-threatening complication of infectious mononucleosis.life-threatening cervical complications associated with infectious mononucleosis are rare. the combination of acute epiglottitis and subsequent necrotizing fasciitis of the head and neck in a patient with infectious mononucleosis has not been reported to date.a 47-year-old female with infectious mononucleosis and epiglottitis was admitted to hospital for i.v. therapy. owing to her poor clinical condition and the spread of the infection to the throat and superior mediastinum, as evidenced by ct, ...200516298800
once bitten, twice shy: an unusual case report of a mycotic aortic aneurysm.primary mycotic aneurysms of the aorta are a rare, but potentially lethal condition comprising less than 1% of all aortic aneurysms. all age groups are affected but patients younger than 50 years are most susceptible. organisms commonly implicated in aortitis and mycotic aortic aneurysms include salmonella species and staphylococcus aureus(1). we present the first case report of a primary aortic mycotic aneurysm caused by capnocytophaga canimorsus, a commensal organism found in the mouth of dogs ...200516336402
capnocytophaga in the dental plaque of immunocompromised children with cancer.(i) to compare the prevalence and levels of capnocytophaga, a known systemic pathogen in immunocompromised patients, in the dental plaque of healthy children and children with cancer, and (ii) to determine the susceptibility of strains isolated from cancer patients to a range of antibiotics.200616430520
capnocytophaga canimorsus mycotic abdominal aortic aneurysm: why the mailman is afraid of dogs.we describe the first case report of a mycotic abdominal aortic aneurysm secondary to capnocytophaga canimorsus in an immunocompetent 65-year-old man. the exposure occurred after his dog scratched his arm and subsequently licked the wound. a review of c. canimorsus, a rarely pathogenic but potentially devastating bacterium, is also presented.200616455937
etiologic diagnosis of capnocytophaga canimorsus meningitis by broad-range pcr. 200616482426
is pre-term labour associated with periodontitis in a danish maternity ward?to reveal differences in periodontal status and presence of subgingival bacteria in a scandinavian population of women with pre-term birth compared with women who delivered at term.200616489943
diagnosing capnocytophaga canimorsus infections.we reviewed clinical and epidemiologic features of 56 human capnocytophaga canimorsus isolates submitted during a 32-year period to california's microbial diseases laboratory for identification. an increasing number of isolates identified as c. canimorsus have been submitted since 1990. many laboratories still have difficulty correctly identifying this species.200616494769
[extensive purpura and septic schock in two patients with capnocytophaga canimorsus].capnocytophaga canimorsus is a gram negative bacillus present in oral flora and in saliva of dogs and cats. it can be responsible for septicaemia and meningitides in some patients after dog or cat bite two patient with a septic shock due to c. canimorsus, who presented with an extensive pupura are reported.200616495847
[meningitis due to capnocytophaga canimorsus without dog bite].capnocytophaga canimorsus is a fusiform and filamentous gram-negative rod, part of the normal oral flora of dogs and cause rare human febrile acute meningitis, usually severe but curable.200616550132
important unusual infections in australia: a critical care perspective.to review a number of the important unusual infections in australia that can lead to critical illness.200116573516
supragingival plaque may modify the effects of subgingival bacteria on attachment loss.bacterial interactions in response to local and systemic factors may explain important features of the pathogenesis of periodontal disease. this study evaluates the role of supragingival plaque level on the relationship between subgingival microorganisms and the risk of attachment loss.200616671872
fatal capnocytophaga infection associated with splenectomy.a case of fatal sepsis due to capnocytophaga species is described. capnatophaga canimorsus and c. cynodegmi can cause localized wound infections and/or systemic infections in people who have been bitten, licked, scratched, or merely exposed to cats or dogs, especially splenectomized individuals. a thorough social, medical, and surgical history, the clinical presentation, and cultures are important in making the diagnosis of capnocytophaga infections. it is important that the forensic pathologist ...200616696717
meningitis due to capnocytophaga canimorsus: contribution of 16s rna ribosomal sequencing for species identification.we report a case of capnocytophaga canimorsus meningitis, which is distinguishable from previous reports by the use of 16s rrna sequencing for species identification. our case report highlights the interest of molecular new tools for bacteriological diagnosis of human infections.200616709541
characterisation of prototype nurmi cultures using culture-based microbiological techniques and pcr-dgge.undefined nurmi-type cultures (ntcs) have been used successfully to prevent salmonella colonisation in poultry for decades. such cultures are derived from the caecal contents of specific-pathogen-free birds and are administered via drinking water or spray application onto eggs in the hatchery. these cultures consist of many non-culturable and obligately anaerobic bacteria. due to their undefined nature it is difficult to obtain approval from regulatory agencies to use these preparations as direc ...200616814892
[suppurative hepatic lesion with extension to soft tissues]. 200616863627
capnocytophaga ochracea causing severe sepsis and purpura fulminans in an immunocompetent patient.capnocytophaga ochracea (c. ochracea), a known human microflora, has been reported to cause sepsis in immunocompromised patients and less severe infections such as intrauterine infections, endocarditis, peritonitis and septic arthritis in the immunocompetent patient. we present the first described case of c. ochracea causing severe sepsis and purpura fulminans in an immunocompetent host.200716882454
periodontal microflora of hiv infected patients with periodontitis.the aim of this study was to determine the microbial profile of periodontal lesions in hiv seropositive patients and to compare it with rapidly progressing periodontal lesions in systemically healthy patients. the subgingival microflora of 20 cdc ii, 20 cdc iii, 20 cdc iv/v and 20 systemically healthy patients with rapidly progressing periodontitis was examined. four sites with greatest probing depth in each patient were selected for microbiological sampling. the samples were cultured aerobicall ...199716887570
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