Publications

dengue fever.		1998	19690
cytotoxicity of oxidation derivatives of cholesterol on cultured aortic smooth muscle cells and their effect on cholesterol biosynthesis.	aortic smooth muscle cell death is an important initial lesion of atherosclerosis. a number of autooxidation products of cholesterol which has been recognized recently has the capability of inducing rabbits' aortic smooth cell death in vitro. twelve oxidation derivatives of cholesterol, available commercially, were dissolved in small amounts of ethanol, then added to the culture medium at levels not exceeding 0.8%. the medium contained 10% fetal calf's serum which served as an in situ vehicle fo ...	1979	34998
["information field dental health", an integral part of continuing dental education].		2000	89765
[effect of human antigens on the biological properties of the causative agents of typhoid fever and paratyphoid b].		1979	91281
the development of mesosomes of staphylococcus aureus during autolysis.	mesosomes of staphylococcus aureus were examined morphologically under the electron microscope. three different methods of specimen preparation (thin section, freeze-fracture, and negative staining) were used to eliminate artifacts due to sample processing. mesosomes were rarely seen in intact cells but were quite distinct in autolysed cells incubated in 1.2m sucrose -0.33m acetate buffer (ph 5.8) at 25 degrees c. the phospholipid content increased by 20% of the control as autolysis proceeded. s ...	1979	91308
[effect of the prolonged administration of chlormadinone acetate on platelet function and blood chemistry with older male persons (author's transl)].		1999	91459
spontaneous interictal spiking in the awake kindled rat.	the spontaneous interictal spike (sis) noted in eeg recordings is a signal of the abnormally excitable behavior of neurons in an epileptic focus. this study provides a detailed, quantitative, temporal and spatial profile of sis in the amygdaloid kindled rat. the reproducible nature of the development and decline of sis in kindling provides a useful model for biochemical study of the mechanisms that initiate and regulate sis.	1979	91486
condensation--inhibition by 33258-hoechst of centromeric heterochromatin in prematurely condensed mouse chromosomes.		1979	91529
[infection as indicator of finding complex environmental noxious agents within a short time (author's transl)].	we do not know whether complexes of chemical agents produce an accumulation of their respective noxious effects or whether these effects weaken each other and we have no exact methods to quantify these effects. knowledge of such methods would be important for investigation of environmental health. in the course of researches how to influence infectious diseases by altering natural resistance we have found that it might be possible to use an indicator method: animals exposed to such a light envir ...	1979	92117
an investigation of the optimal conditions for the in vivo production of immunologically sensitised rat mast cells.	experiments were designed to develop an optimal method for inducing in vivo production of sensitised peritoneal mast cells. rats of different strains were sensitised with whole egg-white and killed at suitable intervals to harvest the peritoneal mast cells. release of histamine was induced in vitro by both whole egg-white and its major protein constituents, and assayed by a standard spectrofluorometric method. wistar rats showed higher levels of sensitisation than black-hooded lister rats; it wa ...	1979	92507
raised maternal serum-alpha-fetoprotein levels and spontaneous fetomaternal transfusion.	study of blood smears showed that spontaneous fetomaternal transfusions were significantly more common among 42 pregnant women with raised serum-alpha-fetoprotein (afp) levels than among 45 pregnant women with normal serum-afp levels. raised serum-afp was associated with a spontaneous fetomaternal transfusion of greater than or equal to 0.1 ml in at least 21 of the 42 women in the study group.	2001	92622
mechanism of the interaction of desipramine with (na+, k+) atpase and p-nitrophenylphosphatase [proceedings].		2001	92937
partial amino acid sequences of rabbit and rat beta 2-microglobulins.		1979	93696
purification of antibodies to influenza a virus structural proteins by affinity chromatography, and their participation in haemagglutination-inhibition, neutralization and enzyme-linked immunosorbent assay.	affinity chromatography was used to purify rabbit antibodies to common and strain-specific antigeneic determinants of haemagglutinin, to neuraminidase, and to a combination of the internal proteins of influenza a viruses. the purity of the antibodies was assessed by haemagglutination-inhibition, enzyme-linked immunosorbent assay (elisa) and competition elisa. the antibodies were examined for their participation in neutralization and haemagglutination-inhibition assays, and in elisa. elisa was fo ...	1979	93960
effect of adrenergic receptor blockade on the responses to isometric handgrip: studies in normal and hypertensive subjects.	heart rate and blood pressure (bp) responses to a standardized 3 min isometric handgrip (ihg) test were measured in 32 normotensive men and compared with those found in 35 age-matched, drug-free men with established essential hypertension (bp range: 140--170/90--110). ihg testing in the normal subjects induced significant increases in heart rate (mean +/- se: 7.6 +/- 3.3 beats/min), systolic blood pressure (19.4 +/- 5.3 mm hg), and diastolic blood pressure (15.6 +/- 4.6 mm hg). although beginnin ...	2000	94394
control of lactate production by selenomonas ruminantium: homotropic activation of lactate dehydrogenase by pyruvate.	selenomonas ruminantium produced one mole of d(-)-lactate per mole of glucose used at all dilution rates in ammonia-limited continuous culture. in contrast, lactate production varied according to the dilution rate when glucose was the limiting nutrient. at dilution rates of less than 0.2 h-1, acetate and propionate were the main fermentation products and lactate production was low. at dilution rates above 0.2 h-1, the pattern changed to one of high lactate production similar to that under ammoni ...	1978	103995
an unstable donor-recipient dna complex in transformation of bacillus subtilis.	in re-extracted dna obtained shortly after uptake of transforming dna by bacillus subtilis, increased amounts of donor dna radioactivity banding at the position of donor-recipient dna complex (drc) are observed in cscl gradients, if the cells are irradiated with high doses of uv prior to reextraction of the dna. qualitatively, the same phenomenon is observed if lysates of transforming cells are irradiated. uv-irradiation of lysates of competent cells to which single-stranded dna is added after l ...	1978	106232
[the operative surgery of cancer of the tongue].		1998	106345
[seasonal changes in spermatozoas and fertility of stallions in the tropics].	an attempt was made to express the relationship of spermiological characteristics with the fertility on the basis of seasonal variability of the fertility of stallions and of the ejaculate quality. a positive correlation between the activity of spermatozoa and the fertility ensues from the values of correlation coefficients. there is a negative correlation between the fertility and the concentration of citric acid. in the other characteristics, i.e. in the production of spermatozoa, volume of ge ...	1998	106512
changes in lung ultrastructure following heterologous and homologous serum albumin infusion in the treatment of hemorrhagic shock.	the object of this study was to compare the ultrastructure pulmonary effects of the infusion of homologous and heterologous serum albumin solution in the treatment of hemorrhagic shock in baboons. adult baboons subjected to hemorrhagic shock were resuscitated with either baboon serum albumin, human serum albumin, or ringer's lactate solution. the lungs were fixed in vivo with potassium pyroantimony, a solution which produces electron dense interstitial precipitation of sodium. the lungs from ani ...	1979	106780
office microbiology.		1979	111268
use of micro-elisa for quantitating antibody to trypanosoma cruzi and trypanosoma rangeli.	of 229 residents of a panamanian village where both trypanosoma cruzi and trypanosoma rangeli are endemic, 52% had antibody to one or both species by the enzyme-linked immunosorbent assay (elisa), 26% were positive by complement fixation, 17% were positive by direct agglutination, and 32% were positive on the basis of clinical impression. although the sensitivity of elisa makes it the procedure of choice for sero-epidemiologic studies, there does appear to be some serologic cross-reactivity betw ...	1979	116559
localization of sodium pump sites in frog urinary bladder.	[3h]ouabain binding in frog and toad urinary bladder was investigated by short-circuit current (scc), scintillation counting and autoradiographic techniques. scc data and analysis of tissue digests following serosal exposure to ouabain showed that ouabain binding and inhibition of na+ transport was completely reversible in toad bladder whereas, in frog bladder, [3h]ouabain was tightly bound and na+ transport remained suppressed even after a 60-min washout. mucosal exposure of frog bladder to [3h ...	2002	123762
investigation on huntington's disease in the canadian prairies. ii. fecundity and fitness.	the reproductive performance of 157 patients with huntington's disease, their 170 normal siblings and 150 matched unrelated controls is presented. comparison with the general canadian prairie population in the appropriate age group is undertaken. patients with huntington's disease are not only more fecund than their unaffected sibs but also out-reproduce unrelated normal controls and members of the general population of corresponding age. their fitness is thus estimated to be 1.14. should the pr ...	2002	123838
xanthine, hypoxanthine and muscle pain. histochemical and biochemical observations.	a suspected case of xanthine oxidase deficiency has been further investigated. the patient complained of arthralgia and myalgia. further studies included histochemical and ultramicroscopic analysis of muscle sarcoplasmic reticulum, and biochemical studies. high levels of xanthine and hypoxanthine were found, while uric acid was absent in the muscle extracts.	2001	125457
poncimarin, a new coumarin from poncirus trifoliata l.	a new coumarinic derivative (poncimarin; c19h22o5; m.p. 140 c degrees) was isolated from unripe fruits of poncircus trifoliata l. which from spectroscopic evidences was formulated as 7-(2,3-epoxy-3-methyl butyloxy)-8-(2,3-epoxy-3-methyl butyl) coumarin.	2002	126585
letter: bromide intoxication.		2002	126712
surface properties and in vitro functional capacities of human t lymphocyte subsets separated by linear density gradients.	human lymphocytes derived from various central and peripheral sources were separated on linear density gradients (ldg). cells from individual density fractions were tested in parallel for: the capacity to form nonimmune rosettes with neuraminidase-treated srbc, the number of surface-associated htla, and in vitro proliferative responses to mitogenic lectins and alloantigens. heterogeneous density distribution profiles were obtained for all sources of human t cells and revealed an organ specificit ...	1979	156234
reversible hypothyroidism in growth hormone-deficient children treated with human growth hormone.	six children with human growth hormone (hgh) deficiency became hypothyroid during the course of their therapy with hgh. this was accompanied by a decreasing growth rate, clinical symptoms of hypothyroidism and decreased serum t4 concentrations. three of the 6 patients returned to the euthyroid state, both clinically and biochemically, with cessation of hgh therapy, and reinstitution of hgh precipitated hypothyroidism again in 2 of the three. the patients who remained hypothyroid have evidence of ...	1975	165211
protein-binding assay for cyclic amp: possible interference by traces of trichloroacetate.		1995	167609
conditional lethal mutants of vesicular stomatitis virus.		1975	169102
relationship of lactate dehydrogenase specificity and growth rate to lactate metabolism by selenomonas ruminantium.	a lactate-fermenting strain of selenomonas ruminantium (hd4) and a lactatenonfermenting strain (ga192) were examined with respect to the stereoisomers of lactate formed during glucose fermentation, the stereoisomers of lactate fermented by hd4, and the characteristics of the lactate dehydrogenases of the strains. ga192 formed l-lactate and hd4 formed l-lactate and small amounts of d-lactate from glucose. hd4 fermended l- but not d-lactate. both strains contain nicotinamide adenine dinucleotide ( ...	1975	174490
a structural study of pig liver glyceraldehyde-3-phosphate dehydrogenase.	a substantial portion of the primary structure of pig liver glyceraldehyde-3-phosphate dehydrogenase has been investigated and the results compared with those previously reported for the pig muscle enzyme. liver and muscle glyceraldehyde-3-phosphate dehydrogenases show the same amino acid content, and the first n-terminal residues occur in the same sequence. no differences in n-terminal residues and amino acid composition have been evidenced by analysis of several tryptic peptides, which account ...	1976	182238
human plasma lipoproteins as accelerators of prothrombin activation.	the activation rate of bovine prothrombin by factor xa and ca2+ has long been known to be greatly enhanced by addition of phospholipid. upon substitution of human plasma lipoproteins for phospholipid (cephalin) in this activation system, only very low density lipoprotein enhances prothrombin activation. low density lipoprotein and high density lipoprotein have no stimulatory effect on prothrombin activation. on the other hand, the sonicated lipid extracts from very low, low, and high density lip ...	1976	182693
the fine structure of a tri-lamellar body in various species of anabaena.		1976	184493
giant cell tumor of soft parts. an ultrastructural study.	the light-microscopic and ultrastructural findings in a case of so-called giant cell tumor of soft parts, localized at the dorsal side of the left foot of a 23-years-old male are described. an amputation of the lower extremity was performed and subsequently chemotherapy with adriamycin was given for 3 months. despite the histology and cytologic malignant appearance and the evident vascular invasion, already present at the time of the first excision, the last known status 2 years later seems favo ...	1990	184582
particulate carbonic anhydrase in homogenates of human kidney.	about 2% of human kidney carbonic anhydrase (carbonate hydro-lyase, ec 4.2.1.1) has been found in particulate fractions. its distribution in the particulate fractions obtained by differential centrifugation suggests that it may be concentrated in the brush border. the particulate enzyme is like red cell carbonic anhydrace c in its susceptibility to inhibition by anions. particulate carbonic anhydrase is firmly bound to the membrane and is not released by incubation at ph 10.6 and 37 degrees c or ...	1976	184830
sv40 and adenovirus early functions involved in dna replication and transformation.		1976	184845
some specific radiological findings and consideration of linitis plastica of the gastrointestinal tract.	linitis plastica denotes a diffuse, intramurally infiltrating, anaplastic carcinoma in a hollow structure resulting in a shrunken organ with thickened walls. microscopically, linitis plastica is characterized by tumor cells in the presence of inflammatory changes with much fibrosis. linitis plastica is found most frequently in the stomach where it may produce the classical "leather-bottle stomach". metastases to the colon are frequent via contiguity along mesenteric fascial planes. therefore, wh ...	1990	185007
cross-reactions between bordetella pertussis and twenty-eight other bacterial species.	cross-reactions between b. pertussis and 28 other bacterial species were studied by various quantitative immunoelectrophoretic methods. a sonicated b. pertussis antigen preparation and a corresponding pooled rabbit antiserum were used as reference system. two of the b. pertussis antigens were cross-reactive with antigens from 17, respectively 19, other bacterial species mainly gram-negative species. as judged by absorption of antibodies, the degree of cross-reactivity of these b. pertussis antig ...	1976	187010
role of dna repair in natural resistance of rat ascites hepatomas to nitrogen mustard.	mechanism of natural resistance of rat ascites hepatomas to nitrogen mustard was examined with tumors, especially ah-13 and ah-44, sensitive and resistant to the chemical, respectively. there was found little difference in the uptake and binding of the chemical among the two lines. in contrast, dna repair activity of the resistant line was higher than that of the sensitive line. this result suggested that natural resistance of ah-44 to the drug may be, at least partially, due to its higher activ ...	1977	193752
the equilibrium constant and the reversibility of the reaction catalysed by nicotinamide-adenine dinucleotide kinase from pigeon liver.	the reversibility of the nad+ kinase reaction was established, and the kinetic parameters of the rate equation in the reverse direction were determined. the equilibrium constant of the reaction was determined by using the purified pigeon liver enzyme and radioactively labelled nicotinamide nucleotides. the relationship between kinetic parameters of the forward and reverse reactions is in reasonable agreement with the measured equilibrium constant. as expected from the proposed mechanism of actio ...	2003	201249
the chronic patient: perspectives from the 29th institute on hospital & community psychiatry. making rehospitalization part of the plan [proceedings].		1994	201559
[acute diarrhea in childhood--new aspects].		1977	202052
fibrous histiocytoma of the tarsus.	a 21-year-old white man had an asymptomatic eyelid mass that had slowly enlarged for one year. on clinical examination the lesion was well circumscribed; it appeared subconjunctivally but provoked no conjunctival inflammation, and had a consistency suggestive of cartilage. microscopic examination showed it was matted and composed of elongated fibro-histiocytes and an evenly distributed population of xanthoma cells and touton giant cells. the lesion was easily removed by local excision because of ...	1977	202162
poly (adp-ribose) polymerase activity in nucleotide permeable cells.		1988	202502
neuromuscular transmission in arterioles of guinea-pig submucosa.	1. intracellular recordings were made from arterioles lying in the submucosa of guinea-pig small intestine. 2. low frequency perivascular nerve stimulation evoked subthreshold excitatory junction potentials which facilitated. 3. higher frequency stimulation caused summation of excitatory junction potentials and the initiation of muscle action potentials. 4. arteriolar constriction was only observed following the initiation of a muscle action potential.	1977	202698
[sebastian kneipp, his life and his work].		1988	202779
mammary tumors, hepatocellular carcinomas, and pancreatic islet changes in c3h-avy mice.	studies of tumor incidence and assorted lesions found in 187 c3h-avy mice throughout their natural life-spans revealed the following: hepatocellular carcinomas occurred in 54.3% of males, mammary carcinomas in 95% of females, pancreatic islet cell adenomas in 9.4% of males and in no females, and pancreatic islet cell hyperplasia in 41% of males and 23% of fefemales. islet cell hyperplasia and adenomas appeared to consist predominantly of alpha and delta cells. multiple tumors, or hyperplasia, or ...	1978	203711
intestinal calcium binding protein levels in the one month old turkey poult.	intestinal calcium binding protein cabp) was studied in one month old poults which had been fed a vitamin d3-deficient diet unsupplemented or with 399, 600, 900 or 1200 i.u. vitamin d3 added per kg. diet. cabp levels increased with vitamin d3 supplementation up to 600 i.u. but showed no further increase with higher dietary vitamin d3. poults supplemented with 600 to 1200 i.u. vitamin d3/kg. diet had an average of 1.03 mg. cabp/g. of duodenal mucosa cells collected. the calcium binding activity o ...	1977	203920
[diaphyseal bone tuberculosis].	the authors report a case of diaphyseal bony tuberculosis, in which the diagnosis was not made for a long time as bony tuberculosis is considered exceptional and owing to the presence of a staphylococcus which oriented the diagnosis towards osteomyelitis. bony tuberculosis certainly affects more easily immigrant patients, in whom one may see multifocal forms, but also affects those who, by their environment, might imagine they are protected, and it is not exceptional to see unifocal forms.	1977	204049
[breast eczema and breast neoplasms. pseudo paget's disease of the breast].		1987	204113
polysomes and polysomal mrnas in sv40-infected cv-1 cells. in vivo observations.	sv40-specific polysomes are relatively larger than host polysomes. both 16 s and 19 s virus-specific late mrnas are found associated with these polysomes and they are present in a ratio of approximately 2 : 1. the rates at which these virus-specific mrnas are translated are the same, so that the relative amounts of virus-specific polypeptides synthesized in the virus-infected cells is determined by the relative amounts of 16 s and 19 s mrnas coding for them.	1978	208616
[mononucleosis syndrome and thrombocytopenic purpura in q fever (rickettsia burneti)].	case of a patient with a mononucleosis syndrome and thrombocytopenic purpura during q fever. this etiology could lead to a systematic search for a rickettsial cause for such a symptomatology with a negative paul-bunnell-davidson reaction.	1978	211604
[prescribing tiapridal for headache and other painful conditions].	tiapridal a new molecule of the benzamide family, raises the pain-threshold level in the mesolimbic system. it has been shown to be effective in 66% of cases of headaches and pain resistant to therapy, and 75% of patients with nausea and vomiting associated with headaches. the average dosage is between 150 and 300 mg or day (1/2 to 1 tablet, 3 times a day). the product is extremely well-tolerated. somnolence, the most frequent side-effect was noted in 17% of cases. because of its excellent toler ...	1988	211605
myasthenia in patients with dermatomyositis: clinical, electrophysiological and ultrastructural studies.	in 4 patients with clinical signs of dermatomyositis, confirmed by electromyography and muscle biopsy, a form of muscle fatigue was detected which was expressed clinically by predominantly proximal motor deficit, with phonation and deglutition disturbances, slightly influenced by prostigmine. in all patients, stimulation of the ulnar nerve at 3--10 hz induced a decrement of muscle-evoked potentials in abductor digiti minimi and at 15--50 hz an increment at the end of the trains (1.2 sec in durat ...	1986	213537
interstitial cystitis: early diagnosis, pathology, and treatment.	in a retrospective review, 52 patients with interstitial cystitis have been studied. patients with persistent lower tract irritative symptoms, repeatedly sterile urine, and negative urine cytology must be suspected of having interstitial cystitis, and a diagnosis of urethral syndrome in such patients is highly questionable until cystoscopy under anesthesia has been performed. we believe that the finding of multiple petechia-like hemorrhages (glomerulations) on the second distention of the bladde ...	1987	213864
postoperative irradiation of glioblastomas. results in a randomized series.	a material of 108 patients with glioblastoma is presented. the series was randomized in two groups: cases only operated upon and cases with postoperative irradiation in addition. patients dead within 2 months after operation were excluded in estimating the real value of the postoperative irradiation. the irradiated cases had a 6-month survival rate of 64 per cent and a one-year survival rate of 19 per cent; the non-irradiated cases a 6-month survival rate of 28 per cent and a one-year survival r ...	1981	216238
[concentration of serum iron and transferrin saturation with iron as indices of changes resulting from chronic exposure to chemicals in industry].	an attempt was undertaken to use the following indices of systemic changes resulting from longlasting occupational exposure to some chemicals: -- ferrum concentration in blood serum, the level of latent capacity to bind ferrum, and the degree of transferrin saturation with ferrum. the examination involved 177 clinically healthy men, aged 18--60. the control group consisted of 40 healthy men, aged 22--60. in 30.5% of persons, deviations were found, which might be induced by disturbances in genera ...	1979	216880
pathobiology of cortical neurons in metabolic and unclassified amentias.	visualization of the neuron in its entirety through the use of the rapid golgi method has permitted detection of several pathobiological features of neurons that are intimately associated with profound mental retardation in infants and children. in cases of unclassified mental retardation, dendrites and particularly dendritic spines exhibit severe developmental abnormalities. dendritic spines, the postsynaptic components of axospinodendritic synapses, may be absent or abnormally long and thin in ...	1979	217050
poliomyelitis in the united states.		1981	217252
the potential histogenic relationship of the peripheral nerve to synovioma.	the belief that synoviomas differentiate from the synovial membrane has been widely accepted. absolute proof is lacking, mainly because precancerous synovial atypia has not been documented in human tissue. during the last 50 years, pain has emerged as one of the significant features of synovioma, occurring very early in the course of the disease in some patients. gross relationship to nerve, cumulative histological data, and theoretical relationships with three other cancers of neural origin sug ...	1979	225019
on the significance of the increase in homovanillic acid (hva) caused by antipsychotic drugs in corpus striatum and limbic forebrain.	the effect of various antipsychotic drugs on the blockade of dopaminergic receptors in striatum and limbic forebrain was examined by establishing dose-response curves for the increase in hva and for the antagonism of d-amphetamine-induced rotation in rats with unilateral lesions of the substantia nigra. a good quantitative correlation was found between dopaminergic blockade in the striatum as reflected by the ed100 for striatal hva increase and the ed50 for rotational antagonism and the occurren ...	1975	242028
[human science. behavioral science. 4. social awareness and human behavior--a theme in sociological behavior theory concerning the patient].		1977	242705
understanding the placenta. part 3: the fetus and the placental barrier.		1978	242832
nursing care supplement series b. specialised care. 10. microvascular surgery.		1979	243250
any complaints?		1979	243251
nursing care study: joint replacement.		1979	243252
the essence of operating room nursing. the problem of isolation.		1979	243437
temporal arteritis and polymyalgia rheumatica.		1981	243839
the medicinal mistletoe.		1981	243851
the nurse who came to play.		1981	243968
induced structural transitions in trna.		1971	248323
[community social service in the field of health education].		2003	262313
suppression of phytohemagglutinin response by fungi from a "leukemia" house.	fungal isolates from the house of a husband and wife who both developed acute myelomonocytic leukemia were assayed for effects on the in vivo response to phytohemagglutinin in guinea pigs. skin responses to intradermal phytohemagglutinin were measured following injections of sterile fungal extracts. isolates of penicillium canescens, curvularia, fusarium sambucinum, fusarium equiseti and trichoderma koningii from the leukemia-associated house depressed the responses to phytohemagglutinin, but no ...	1979	291385
inactive mrna-protein complexes from mouse sarcoma-180 ascites cells.	mouse sarcoma ascites cells do not utilize fully their capacity for protein synthesis. a considerable portion of their ribosomes occur as inactive monomers. also, a substantial amount of the cellular mrna is in the form of ribonucleoprotein particles that sediment in the 20-70s range. this is indicated both by measurements of poly(a) content and by translation of the rna in cell-free systems. the population of polypeptides synthesized under the direction of the rna from these particles is less h ...	1979	293664
structure of carboxymyoglobin in crystals and in solution.	the configuration of the heme-carbonyl group upon binding of carbon monoxide to sperm whale myoglobin (mb) in crystals is evaluated on the basis of infrared spectroscopic methods. multiplets of the totally symmetric c-o stretching mode are observed for the heme-bound ligand near 1933, 1944, and 1967 cm-1, corresponding to three different heme-carbonyl conformers. variations in the relative proportions of these conformers can be induced by incorporation of small fractions of metmb or deoxymb into ...	1980	293700
a possible folding pathway of bovine pancreatic rnase.	a theoretical pathway for the folding of rnase into its native conformation is derived from the contact map computed from crystallographic coordinates. the pathway is based on the hypothesis of tanaka and scheraga, according to which localized conformations stabilized by short- and medium-range interactions form before those conformational features that are stabilized primarily by long-range interactions. the pathway deduced from the contact map agrees with experimental information on intermedia ...	1979	293701
[from our master examination].		2004	355976
biochemical and topographical studies on escherichia coli cell surface. iv. giant spheroplast formation from a filamentous cell.	long, nonseptate filamentous cells consisting of 5 to 40 single-cell unit lengths were formed from escherichia coli surface mutant ont-3 by treatment with a sublethal concentration of sodium dodecyl sylfate. as distinct from several other elongated cells (e.g., thymine-starved filaments), it was found here that stable giant spheroplasts, 5 to 10 micrometers in diameter, were produced by the action of lysozyme in the presence of bovine serum albumin via the gradual fusion of distinct spheroplasti ...	1979	374397
thyrotrophin releasing hormone-induced growth hormone and prolactin release: physiological studies in intact rats and in hypophysectomized rats bearing an ectopic pituitary gland.	to determine how the sensitivity of the ectopic anterior pituitary gland to the gh-releasing effect of thyrotrophin releasing hormone (trh) might be affected by the time lapse from transplantation, trh (0-15 and 0-6 microng) was injected i.v. into hypophysectomized (hypox)-transplanted rats under urethane anaesthesia 1,3,8,15,30 and 60 days after transplantation, and plasma samples were taken 5 and 10 min later. baseline gh values gradually decreased with time from about 16-0 ng/ml (1 day) to ab ...	1977	404376
pleural effusion: a diagnostic dilemma.		2004	404437
demonstration of 5'-methylthioadenosine phosphorylase activity in various rat tissues. some properties of the enzyme from rat lung.	an enzyme (5'-methylthioadenosine phosphorylase) that catalyzes the phosphorolytic cleavage of 5'-methylthioadenosine to 5-methylthioadenosine to 5-methylthioribose-1-phosphate and adenine was found in various rat tissues. liver and lung had the highest enzyme activities and heart the lowest, most of the activity (greater than 90%) was recovered in soluble tissue fractions. the enzyme from rat lung was purified about 30-fold by ph treatment (nh4)2so4 fractionation, and gel filtration. the enzyme ...	1978	415762
some effects of uncouplers and inhibitors on growth and electron transport in rumen bacteria.	uncouplers and inhibitors of electron transport affected growth and electron transport of rumen bacteria in various ways. selenomonas ruminantium was not affected by inhibitor and uncoupler concentrations which affected growth and electron transport of bacteroides ruminicola, b. succinogenes, and butyrivibrio fibrisolvens. inhibitors, when active, led to accumulation of reduced electron carriers before the site of action, but differences were found among organisms in the site of action of these ...	1979	457609
synthesis of alpha-ketoglutarate by reductive carboxylation of succinate in veillonella, selenomonas, and bacteriodes species.	evidence for reductive carboxylation of succinate to synthesize alpha-ketoglutarate was sought in anaerobic heterotrophs from the rumen and from other anaerobic habitats. cultures were grown in media containing unlabeled energy substrates plus [14c]succinate, and synthesis of cellular glutamate with a much higher specific activity than that of cellular asparate was taken as evidence for alpha-ketoglutarate synthase activity. our results indicate alpha-ketoglutarate synthase functions in selenomo ...	1979	533772
transformation of mercuric chloride and methylmercury by the rumen microflora.	the microflora in strained rumen fluid did not methylate or volatilize 203hg2+ at detectable rates. however, there was an exponential decay in the concentration of added ch3hg+, which was attributed to demethylation. the major product of demethylation was metallic mercury (hg0), and it was released as a volatile product from the reaction mixture. demethylation occurred under both anaerobic and aerobic conditions. the rate of demethylation was proportional to the concentration of added ch3hg+-hg ...	1979	539820
[visual field changes in mesopic and scotopic conditions using friedmann visual field analyser. iii. acquired chorioretinal diseases (author's transl)].		2005	546186
alkaline phosphatase activity of rumen bacteria.	of the 54 strains of rumen bacteria examined for alkaline phosphatase (apase) production, 9 of 33 gram-negative strains and none of 21 gram-positive strains produced the enzyme. the apase of the cells of the three strains of bacteroides ruminicola that produced significant amounts of the enzyme was located in the periplasmic area of the cell envelope, whereas the enzyme was located in the strains of selenomonas ruminantium and succinivibrio dextrinosolvens was associated with the outer membrane. ...	1977	563216
effects of heavy metals and other trace elements on the fermentative activity of the rumen microflora and growth of functionally important rumen bacteria.	the inhibitory effects of high concentrations of essential and non-essential trace elements were tested on the rumen microflora using the rate of fermentation in vitro as the assay. the elements (and the concentration causing 50% inhibition) in decreasing order of toxicity were hg2+ (20 microgram/ml), cu2+ (21 microgram/ml), cr6+ (70 microgram/ml), se4+ (73 microgram/ml), ni2+ (160 microgram/ml), cd2+ (175 microgram/ml), as3+ (304 microgram/ml) and as5+ (1610 microgram/ml). the elements tested t ...	1978	565671
production of branched-chain volatile fatty acids by certain anaerobic bacteria.	net production of isobutyric acid, isovaleric acid, and 2-methylbutyric acid by cultures of bacteroides ruminicola and megasphaera elsdenii on media that contained trypticase or casein hydrolysate continued (up to 5 days) after growth had ceased. only trace quantities of these acids were produced in a medium that contained a mixture of amino acids that did not include the branched-chain amino acids. m. elsdenii produced increased quantities of the branched-chain fatty acids in a medium that cont ...	1978	566082
influence of ch4 production by methanobacterium ruminantium on the fermentation of glucose and lactate by selenomonas ruminantium.	a method is described for increasing the production of h2 from glucose or lactate by selenomonas ruminantium by sequential transfers in media containing pregrown methanobacterium ruminantium. the methanogen uses the h2 formed by the selenomonad to reduce co2 to ch4. analysis of fermentation products from glucose showed that lactate was the major product formed from glucose by s. ruminantium alone. several sequential transfers in the presence of the methanogen caused a marked decrease in lactate ...	1977	596874
h2 production by selenomonas ruminantium in the absence and presence of methanogenic bacteria.	selenomonas ruminantium is a nonsporeforming anaerobe that ferments carbohydrates primarily to lactate, propionate, acetate and co2. h2 production by this species has not been previously reported. we found, however, that some strains produce trace amounts of h2 which can be detected by sensitive gas chromatographic procedures. h2 production is increased markedly, in some cases almost 100-fold, when the selenomonads are co-cultured with methane-producing bacteria. growth of the methane-producing ...	1975	804850
effect of ruminal lactic acid-utilizing bacteria on adaptation of cattle to high-energy rations.	heifers, unadapted to a concentrate ration, were intraruminally inoculated (1 dose) with cultures of ruminal lactic acid-utilizing bacteria or with ruminal fluid from a steer adapted to a concentrate ration. inoculation with cultures (1 l) of selenomonas ruminantium or megasphaera elsdenii did not produce better average daily weight gains or feed efficiency of heifers fed a high-energy ration for 21 days, if these values were compared with the performance of noninoculated heifers. average daily ...	1977	883707
lactic acid-utilizing bacteria in ruminal fluid of a steer adapted from hay feeding to a high-grain ration.	a mature, rumen-cannulated steer fed coastal bermuda grass hay for 8 weeks was adapted to a high-grain ration by stepwise increases in grain over a period of 4 weeks. the grain rations had concentrate-to-roughage ratios of 40:60, 70:30, and 85:15 and were fed for 10, 7, and 11 days, respectively. numerical estimates of lactate-utilizing bacteria in ruminal fluid of the steer the last 3 days each ration was fed were made by colony counts. lactate-utilizing bacteria were identified as megasphaera ...	1976	1275348
dap-decarboxylase activity and lysine production by rumen bacteria.	the last step of pathway of lysine biosynthesis by rumen bacteria was tested. the first measurements of dap-decarboxylase activity and of lysine production by megasphera elsdenii, selenomonas ruminantium, clostridium spp., butyrivibrio fibrisolvens and bacteroides succinogenes as well as the first attempts to increase the lysine production by ruminal streptococci by mutation are described. the highest values were measured in selenomonas ruminantium (dap-decarboxylase activity = 146 micrograms da ...	1992	1295484
complete nucleotide sequence of a selenomonas ruminantium plasmid and definition of a region necessary for its replication in escherichia coli.	a plasmid from selenomonas ruminantium subspecies lactilytica has been subcloned in escherichia coli k-12 and completely sequenced. three open reading frames (orfs) of 909, 801, and 549 bp were identified and the complete sequence was analyzed by comparison with dna and protein databases. no significant deoxynucleotide or amino acid sequence homology with other published genes or proteins was detected. the plasmid was shown to replicate independently in e. coli k-12 by a dna polymerase i-depende ...	1992	1409969
mechanism of action of d-galacturonan digalacturonohydrolase of selenomonas ruminantium on oligogalactosiduronic acids.	the mechanism of action of the specific d-galacturonan digalacturonohydrolase [poly-(1----4)-alpha-d-galactosiduronate digalacturonohydrolase, ec 3.2.1.82] of selenomonas ruminantium was investigated by using reducing-end [1-3h]-labeled oligogalactosiduronates having degree of polymerization 3-5 as the substrates. the reaction products, incorporation and distribution of radioactivity in products, and the frequency of oligogalactosiduronate bond-cleavage were quantitatively estimated as functions ...	1992	1473108
effect of direct-fed microbials on rumen microbial fermentation.	nonbacterial, direct-fed microbials added to ruminant diets generally consist of aspergillus oryzae fermentation extract, or saccharomyces cerevisiae cultures, or both. results from in vivo research have been variable regarding effects of direct-fed microbials on ruminant feedstuff utilization and performance. some research has shown increased weight gains, milk production, and total tract digestibility of feed components, but others have shown little influence of direct-fed microbials on these ...	1992	1500571
australia's most pressing social problem: nursing vs non-nursing students' views.	nursing and non-nursing students (n = 297) were surveyed in 1989 for their opinion of 'australia's most pressing social problem'. significant differences were found between the two groups. although race relations in australia headed the concerns of both groups of students, nursing students consistently chose health-related issues as their choices for 'the most pressing social problem' facing the australian nation. several explanations for this 'focused' interest of nursing students are discussed ...	2006	1538676
interaction of ruminal bacteria in the production and utilization of maltooligosaccharides from starch.	the degradation and utilization of starch by three amylolytic and one nonamylolytic species of ruminal bacteria were studied. pure cultures of streptococcus bovis jb1, butyrivibrio fibrisolvens 49, and bacteroides ruminicola d31d rapidly hydrolyzed starch and maltooligosaccharides accumulated. the major starch hydrolytic products detected in s. bovis cultures were glucose, maltose, maltotriose, and maltotetraose. in addition to these oligosaccharides, b. fibrisolvens cultures produced maltopenta ...	1992	1539992