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relation between meteorological factors and pain in rheumatoid arthritis in a marine climate.reports indicate that weather conditions may affect some symptoms of rheumatoid arthritis (ra) but not the disease itself. eighty-eight patients living in the marine climate of the dutch coastal provinces scored their pain symptoms daily during a full year. correlation analyses of monthly patient averaged pain scores against each of 6 weather factors indicated that ra pain associates positively and quite significantly (p less than 0.01) with temperature and with vapour pressure, negatively and s ...20144057193
extravasation of polymorphonuclear leukocytes from the cerebral microvasculature. inflammatory response induced by alpha-bungarotoxin.postcapillary venules represent the segment of the microvasculature most vulnerable to inflammatory processes. while there is a considerable body of data on the peripheral vasculature, little is known about the primary events occurring during inflammatory reactions in cerebral blood vessels. we introduce here a model by which the migration of polymorphonuclear leukocytes through the cns endothelial barrier can be studied. alpha-bungarotoxin is used as a chemotactic agent and is shown, for the fi ...19854053172
[the roller discotheque--a quickstep to the hospital? an analysis of 196 accidents].a retrospective study comprising a period of 16 months was made in order to analyse the injuries of 196 patients occurred when visiting a roller discothèque. injuries of the upper extremities had the highest incidence (56.6%); the most frequent of these lesions was the distal fracture of the radius (23.4%, n = 46). rather slight injuries are predominant indeed, however, even severe injuries are observed, e.g. supracondylar fractures of the humerus, fractures of the ankle joint, or vertebral frac ...20144049572
fee and expected therapeutic outcome. 20144046930
selective regulation of carboxypeptidase peptide hormone-processing enzyme during enkephalin biosynthesis in cultured bovine adrenomedullary chromaffin cells.bovine adrenomedullary chromaffin cells in culture were incubated with reserpine or forskolin, two agents acting through different mechanisms, which increase cellular [met]enkephalin levels by 2-fold after 72 h. cells were harvested and chromaffin granules were purified on a linear sucrose gradient. after reserpine treatment, carboxypeptidase-processing enzyme specific activity in chromaffin granule fractions was stimulated 1.9-fold, and co2+-stimulated carboxypeptidase specific activity was sti ...19854039723
determination of treatment disposal for parasuicide patients in a german university hospital. 20134035455
tabulation and assessment of 113 human surveillance cytogenetic studies conducted between 1965 and 1984.there is an increasing tendency to monitor human exposure to genotoxic chemicals by the assessment of chromosomal aberrations or sister-chromatid exchanges (sces) in peripheral blood lymphocytes. in order to assess the sensitivity of these techniques, and to discern minimal criteria for their conduct, a survey of 113 human lymphocyte cytogenetic surveillance studies conducted between 1965 and 1984 has been undertaken. the present survey indicates the urgent need for standardization of study prot ...19854033683
[sequential histochemical studies of the esophageal carcinoma in rats induced by n-methyl-n-amylnitrosamine]. 19854032830
dyschondroplasia/osteochondrosis of the femoral trochanter in the fowl.of 104 lame broilers, 12 birds with femoral trochanteric abnormalities were identified by post-mortem and radiographic examination. defects occurred in ossification of either the trochanteric zenith or its medial aspect. lesions were identified as dyschondroplasia, osteochondrosis or osteochondrosis dissecans affecting the articular surface of the femoral trochanter. in the absence of concomitant musculoskeletal disease, degrees of lameness can be attributed to trochanteric lesions. breaches in ...19854031131
immunization and immunosuppression in mice reared for high or low immune responsiveness against nematospiroides dubius. 19854030203
preferential uptake of intravenously administered hyaluronidase (hyalosidase) by damaged rat myocardium.the induction of myocardial infarction in rats by ligation of the left-anterior coronary artery was confirmed by measurement of increased plasma levels of creatine kinase, aspartate aminotransferase and lactate dehydrogenase. using this model system it has been established that intravenous administration of 125i-labelled hyaluronidase to rats resulted in a preferential uptake of the enzyme by damaged myocardium as compared to normal heart tissue.19854027352
nasogastric intubation as sole treatment of caustic esophageal lesions.in this partly retrospective and partly prospective study, we examined 200 patients with suspected caustic ingestion. no steroids were administered to the patients involved. lesions in the esophagus were found in 93 patients. thirty-two patients with deep circular burns had nasogastric tubes inserted immediately. of these patients, two developed esophageal strictures, but subsequent dilatation was successful. no stricture formation was observed in the group of patients with noncircular lesions. ...20144026118
trends in cancer mortality in italy, 1955-1978.trends in age-specific and age-standardized cancer death certification rates in italy from 1955 to 1978 were analyzed. in males total cancer mortality rates increased in all age groups. however, when respiratory and other tobacco-related neoplasms were excluded, death certification rates were roughly stable up to age 64. moderate decreases in overall cancer mortality have been apparent at younger ages (35-44) since the early 1970's. in females, all the age-specific and the age standardized, unde ...19854024279
factors affecting survival after ruptured abdominal aortic aneurysm.to identify the factors affecting the high mortality rates associated with ruptured abdominal aortic aneurysm (aaa), a review was made of the records of 81 patients treated surgically between 1972 and 1983. correlation of data with survival and predictive value of preoperative findings were studied. the mortality rate was 43.2%; there was a 29.2% mortality rate among those surviving the day of surgery. patient-determined variables associated with deaths included age more than 76 years, hematocri ...20144009838
excretion of radioactivity in faeces and urine of rats injected with 3h,14c-lipopolysaccharide.the route of excretion of lipopolysaccharide (lps) and its possible degradation in vivo was studied in rats using biosynthetically radiolabelled lps from salmonella abortus equi, carrying 3h activity exclusively in fatty acids and 14c activity in fatty acids and sugars. following intravenous injection of the above lps in as2 rats with or without anaesthesia, excretion of radioactivity occurred mainly in the faeces and to smaller extent in urine. the rate of excretion was slow, a large part of th ...19854005148
copper deficiency in infants fed cow milk. 19853998919
bleeding pattern before admission as guideline for emergency endoscopy.in a prospective study of 539 patients admitted because of hematemesis and melena the bleeding pattern before admission was compared with the findings obtained on emergency endoscopy and the subsequent clinical course. ranked in order of prognostic importance, red hematemesis with melena, black hematemesis with melena, and red hematemesis alone increased the probability of massive hemorrhage. moreover, black hematemesis with melena was the superior predictor of bleeding ulcer, the commonest lesi ...20143992165
the significance of 3-metoxy-4 hydroxyphenyl-glycol, a monoaminic metabolite. 20143992160
injections of atropine into the caudate nucleus impair the acquisition and the maintenance of passive avoidance.two experiments were performed to test the hypotheses that cholinergic activity of the caudate nucleus (cn) is involved in the acquisition and in the maintenance of passive avoidance behavior. rats were trained, in one trial, to avoid one of two compartments of a conditioning box and retention of the task was measured 24 hours later. several doses of atropine were injected into the cn of independent groups of animals. in experiment 1 the atropine was injected 2 minutes after training and in expe ...19853983217
hypercalcemia in the neuroleptic malignant syndrome.the neuroleptic malignant syndrome (nms) developed in a 32-year-old man following fluphenazine enanthate administration. hypercalcemia was initially present, perhaps reflecting release of calcium from skeletal muscle stores. the elevated serum calcium levels support the existence of a peripheral muscle abnormality in the pathogenesis of the nms and provides another point of similarity between nms and malignant hyperthermia.19853970627
short-term admission for behavior modification.twenty-four children with behavioral problems were hospitalized for four days for intensive enhancement of their parents' parenting skills and a behavior modification program. this method was employed as an alternative approach to an ongoing problem. a questionnaire was designed to gauge parent satisfaction with the results. seventeen children were rated as having improved behavior from four to 36 months after discharge. a standard behavioral checklist was employed before hospitalization (nine p ...20143946353
enhanced responsiveness of the coronary blood vessel of the dog heart-lung preparation to pgi2 after chronic chemical sympathectomy.chronic chemical denervation of the sympathetic nervous system with 6-oh dopamine resulted in an augmentation of the coronary blood flow (cbf) increase inherent in the canine heart-lung preparation, but not in an augmented accumulation of 6-keto pgf1 alpha in the circulating blood. in denervated hlp, 6-keto pgf1 alpha was lower and the vasodilator response to pgi2 larger at the start of the experiments. it was concluded that exaggerated increase in cbf was due to a potentiation of the vasodilato ...19853932732
stoichiometry and kinetics of the interaction of prostaglandin h synthase with anti-inflammatory agents.we have examined the kinetics, stoichiometry, and chemical nature of the interaction of three anti-inflammatory agents (indomethacin, flurbiprofen, and meclofenamic acid) with pure ovine prostaglandin h synthase. the kinetics of the interaction with the synthase for each of the three agents, monitored by the decrease in cyclooxygenase activity, was consistent with the model proposed by rome and lands (rome, l.h., and lands, w.e.m. (1975) proc. natl. acad. sci. u.s.a. 72, 4863-4865): a rapid and ...19853930499
the relationship of fetal plasma protein concentration and hemoglobin level to the development of hydrops in rhesus isoimmunization.fetoscopic samples of pure fetal blood were obtained at 18 to 25 weeks' gestation from seven hydropic and 10 nonhydropic fetuses affected by rhesus isoimmunization, and the fetal plasma albumin, plasma total protein, and hemoglobin concentrations were determined. all fetuses with sonographic evidence of hydrops had a hemoglobin of 3.8 gm/dl or less, whereas all but one of those without hydrops had a hemoglobin greater than 4.0 gm/dl. the plasma total protein was less than 2 standard deviations b ...20143923839
protein antigens of encapsulated klebsiella pneumoniae surface exposed after growth in the presence of subinhibitory concentrations of cephalosporins.it recently has been reported by us that cephalosporins, at a concentration below that influencing growth rate, reduced the production of enterochelin and capsule formation of iron-depleted klebsiella pneumoniae. we now report on the antigenicity of the outer membrane components and surface-exposed protein antigens of iron-depleted cells grown in the presence or absence of cephalosporins. all major outer membrane proteins, including iron-regulated membrane proteins, were immunogenic. encapsulate ...19853914857
management of perioral burn scarring in the child and adolescent.the experience gained in the treatment of 116 patients with perioral burn scarring is presented. important considerations are the choice of unit release or simple release, the choice of donor site to match the prevailing skin of the remainder of the face, and the timing of the reconstruction. delaying the reconstructive procedure with the routine use of pressure appliances until the scar was mature produced a more pleasing final result. in addition, we found that modifying the traditional aesthe ...20143909897
[a model of the oral glucose tolerance test]. 20143896011
[a utility arch for maximum anchorage]. 20133870256
[keypoints in nursing observation of sle patients]. 20133853704
discharge planning: it's different at night. 20133851770
[the professional responsibility of the nurse]. 20133845649
delayed lactate clearance in patients surviving circulatory shock. 20133843372
diversity and structure of genes of the alpha family of mouse t-cell antigen receptor.we have analysed 19 complementary dna clones encoding the alpha-chain of the t-cell antigen receptor derived from thymic transcripts, and find that 15 of them contain partial or complete variable (v alpha) genes. seven of these genes cross-hybridize to over 40 germline v alpha gene segments in southern blot analyses. of the 19 joining (j alpha) sequences examined, 18 seem to be encoded by distinct gene segments, hence the repertoire of j alpha gene segments is much larger than those of the immun ...19853839904
[retinopathy of prematurity (vi)--changing the fundus findings of rop into the quantity evaluation]. 20133839623
identification of two cases of bovine undifferentiated tumours (squamous cell carcinoma and adenocarcinoma) by electron microscopy.two cases of undifferentiated tumours were found in cows. electron microscopy revealed that one was an undifferentiated squamous cell carcinoma of unknown primary site and the other an undifferentiated adenocarcinoma of the lung.19853837797
nutritional status of the high esophageal cancer risk population in linxian, people's republic of china: effects of vitamin supplementation.plasma levels of nutrients in 196 individuals were assayed as part of a study of the feasibility of a nutrition intervention trial in linxian, a county in north central china with exceptionally high rates of esophageal cancer. high-performance liquid chromatography analyses of samples collected in april 1983 showed low (relative to united states standards) base-line levels for retinol, alpha-tocopherol, and beta- and alpha-carotene. repeat sampling in august 1983 revealed significantly increased ...20133834339
[uv irradiation of autologous blood in the combined treatment of lymphedema of the lower extremities].based on the experience with the treatment of 144 patients the authors recommend to use transfusions of autologous blood subjected to uv irradiation in the complex treatment of lymphostasis of lower extremities.20133832538
benoxaprofen--adverse reactions and monitoring in general practice.we report on the pattern of use of benoxaprofen (opren) in a single group practice for a period which included the complete clinical life of the drug. one hundred and seventy-two patients of the 6495 practice patients had been prescribed benoxaprofen, but 55% had only a small exposure (less than 20 g). recorded adverse reactions, of which none was serious, appeared in 25 patients. most were taking benoxaprofen for osteoarthritis (53%) or non-specific musculoskeletal pain (39.9%). the issue of a ...20133828196
[the effect of a 100 kilometer run on total cholesterol, hdl-cholesterol, triglyceride and lipoprotein levels]. 20133824934
influence of mouse genotype on responses of central biogenic amines to alcohol intoxication and aging.dopamine and serotonin responses to various periods of alcohol treatment have been followed in striatum and hippocampus of two inbred strains of mice and related to the effect of aging. a striking strain dependency was noted for chronic alcohol effects and also for senescence. for both neurotransmitters studied the c57bl strain loses tolerance to prolonged alcohol injury earlier than the balb/c strain. this loss of tolerance accompanying aging may be indicative of more widespread changes in cns ...19863814344
[surgical indications in the asymptomatic gallstone].as long as long-term observations of operated and nonoperated patients with silent gallstones are missing, the question of general, differentiated or absent indication for operation in such cases cannot be answered by facts. to day only by 20% of people with gallstones are operated. 50-70% of those with silent gallstones probably remain free of complaints and symptoms during life. each case of symptomatic cholelithiasis must be operated as soon as possible, but a general indication for operation ...20133807594
immunization with heat-killed pneumococci, but not pneumococcal capsular polysaccharides, improves survival in splenectomized mice.immunization with pneumococcal capsular polysaccharides (pn ps) is advocated after splenectomy to decrease the risk of overwhelming sepsis. the clinical and experimental evidence for the benefit of immunization after splenectomy is controversial. various reports in the literature have claimed a benefit of immunization after splenectomy, but careful review of methodologies reveals that heat-killed pneumococci (pn) were used to immunize the experimental animals. since we have not been able to prot ...19873807350
[neutralization of low molecular weight heparin kabi 2165 by protamine chloride].low molecular weight (lmw) heparin kabi 2165 possesses improved pharmacodynamic properties compared with conventional heparin. it is currently investigated in the prophylaxis of thromboembolism. the neutralization of kabi 2165 by protamine chloride was analysed after i.v. injection of both the agent and the antidot in healthy persons. the anticoagulant effects of the lmw heparin on the activated partial thromboplastin time, thrombin, and thromboelastography are completely and immediately suppres ...20133807263
[the effect of neythumun in comparison with 2-cyanoethylurea on the white blood count of the rat].the stimulation effect of neythymun-sol f+k (nthy) and 2-cyanethylcarbamide (cec) on the leucocytopoesis was studied in 30 wistar rats and a moderate but significant increase in the total number of leucocytes was found. the increase produced by cec didn't prove significantly higher than that by nthy. after 32 d the blood count showed a substantial difference concerning the neutrophils with an increase from 3000 to 9000 without deviation to the left, which was found only under neythymun. this com ...19863797457
immunoelectrophoresis in quality control of veterinary clostridial products.each year the pharmaceutical industry produces 150-250 batches of anti-clostridial vaccines and sera for veterinary use in the u.k. under medicines act requirements these products must be tested for potency before release to the public, such tests being performed in animals. the ministry of agriculture, as licensing authority, also carries out potency test on representative samples of these products. to avoid unnecessary use of animals we employ immunoelectrophoresis (iep) as a screening test. r ...19863792642
unusual association of bone marrow necrosis, disseminated intravascular coagulation, and a rare 8;16 chromosomal translocation in an adult patient with acute nonlymphocytic leukemia.in a patient with acute nonlymphocytic leukemia of the classic type (fab subtype m2), three infrequently observed phenomena occurred together; bone marrow necrosis, disseminated intravascular coagulation, and an 8;16 chromosomal translocation. all three resolved with antileukemic therapy, only to reemerge when the leukemia relapsed, suggesting a causal relationship among these phenomena. such observations and the consistent application of cytogenetic studies to patients with leukemia may help el ...19873791177
hydatid disease: research and control in turkana. ii. the role of immunological techniques for the diagnosis of hydatid disease.immunological studies have been applied to the immunodiagnosis of human hydatidosis in turkana and for the specific identification of echinococcus eggs, particularly in regard to their potential for the assessment of a hydatid control programme in the north-west of the district. a high rate of false negatives has been obtained with sensitive antibody tests for proven hydatid patients in turkana and presents problems for prevalence estimation in the population. a seroepidemiological study using s ...19863787677
influence of single neonatal treatment with allylestrenol or diethylstilbestrol on microsomal enzyme activity of rat liver in adulthood.a single neonatal treatment of rats with a steroid (allylestrenol or diethylstilbestrol) did not alter the later activity of the hepatic microsomal (cytochrome p-450) enzyme system, but inhibited the inducer action of another steroid (testosterone) administered at the age of six weeks. this suggests that a hormonal imprinting-like mechanism also operates in the case of enzymes.19863784633
influence of single neonatal treatment with allylestrenol or diethylstilbestrol on microsomal enzyme activity of rat liver in adulthood.a single neonatal treatment of rats with a steroid (allylestrenol or diethylstilbestrol) did not alter the later activity of the hepatic microsomal (cytochrome p-450) enzyme system, but inhibited the inducer action of another steroid (testosterone) administered at the age of six weeks. this suggests that a hormonal imprinting-like mechanism also operates in the case of enzymes.19863784633
physiology: is it time to cross the new frontier? 20133781974
[antiviral properties of various extracts of natural origin]. 20133777778
[detection of the thyrostatic drug methylthiouracil (mtu) using high performance liquid chromatography (hplc) and high performance thin layer chromatography in tissues and tissue extracts of fattening cattle]. 19863775348
pulmonary function testing in the screening of workers: guidelines for instrumentation, performance, and interpretation.medical surveillance of workers exposed to potential respiratory hazards may be a valuable tool in early recognition and prevention of certain occupational lung diseases. the use of pulmonary function tests, particularly spirometry, has been widely accepted as an integral part of respiratory surveillance. a national aeronautics and space administration contract report on the occupational safety and health administration medical and workplace surveillance requirements and recommendations by the n ...20123772542
pulmonary function testing in the screening of workers: guidelines for instrumentation, performance, and interpretation.medical surveillance of workers exposed to potential respiratory hazards may be a valuable tool in early recognition and prevention of certain occupational lung diseases. the use of pulmonary function tests, particularly spirometry, has been widely accepted as an integral part of respiratory surveillance. a national aeronautics and space administration contract report on the occupational safety and health administration medical and workplace surveillance requirements and recommendations by the n ...20123772542
adequacy of chemically defined, water-soluble diet for germfree balb/c mice through successive generations and litters.to determine dietary adequacy, germfree balb/cann mice were fed ad libitum an ultrafiltered solution of chemically defined, water-soluble, low-molecular-weight nutrients. they received a measured daily supplement of membrane-filtered, distillation-purified soy oil containing vitamins a, d, e and k. mice were kept on ash-free filter paper bedding, which they freely consumed. on this regimen, germfree balb/c mice reproduced through nine generations, and through eight litters in one generation. ave ...20123772524
adequacy of chemically defined, water-soluble diet for germfree balb/c mice through successive generations and litters.to determine dietary adequacy, germfree balb/cann mice were fed ad libitum an ultrafiltered solution of chemically defined, water-soluble, low-molecular-weight nutrients. they received a measured daily supplement of membrane-filtered, distillation-purified soy oil containing vitamins a, d, e and k. mice were kept on ash-free filter paper bedding, which they freely consumed. on this regimen, germfree balb/c mice reproduced through nine generations, and through eight litters in one generation. ave ...20123772524
simple diagnosis of the zellweger syndrome by gas-liquid chromatography of dimethylacetals.the absence of peroxisomes in patients with the cerebrohepatorenal syndrome of zellweger leads to several biochemical abnormalities, including deficient synthesis of plasmalogens as well as accumulation of very long-chain fatty acids and intermediates in bile acid biosynthesis. accumulation of very long-chain fatty acids in serum and fibroblasts has hitherto been used most extensively for diagnosis. due to the relatively small amounts of the very long-chain fatty acids also in the zellweger pati ...20083760714
effect of sodium pentobarbital on behavioral thermoregulation in rats and mice.in this study on behavioral thermoregulation, male sprague-dawley rats were given intraperitoneal (ip) injections of sodium pentobarbital in doses of 0, 1, 5, 10 or 15 mg/kg and male cba/j mice were given doses of 0, 5, 10, 15 or 30 mg/kg. the animals were immediately placed in a temperature gradient which allowed them to select their preferred ambient temperature (ta). the preferred ta of rats increased following an injection of 10 mg/kg sodium pentobarbital, whereas, the barbiturate had no eff ...19863754969
diagnosis of wide qrs tachyarrhythmias: poor atrial echogram specificity in cases of atrioventricular association. 20133751944
teaching in medicine.this brief review has highlighted the important role of the clinician as a medical teacher. indeed, it is difficult to be one without the other. the aims and challenges to medical education have been described, together with the various settings in which teaching can occur. the medical teacher has a range of functions, including the development of educational programmes for special groups, a knowledge of a wide range of techniques for medical education and the ability to identify informal teachi ...20133738474
a laboratory investigation of two new portable gas analysers.two new portable infrared gas analysers, the irina (drägerwerke, lübeck, germany) and the normac (datex instrumentarium corporation, helsinki, finland), were tested and the results compared to those from such established methods as gaschromatography and the beckman lb-2 (beckman, usa) infrared gas analyser using exactly defined gas mixtures from a vaporizer developed in our laboratory. the analysers were evaluated for their accuracy and precision, noise, zero stability, gain stability and the im ...20133722981
hypermagnesemia and progression of renal failure associated with renacidin therapy.renacidin is a urinary stone dissolving agent composed primarily of gluconic and citric acids and their magnesium salts, buffered to a ph of 4. we describe its use in a child with oxalosis, disabling renal colic and deteriorating renal function in whom its use was associated with hypermagnesemia and rapid progression of the renal failure. possible mechanisms for the deterioration in renal function are discussed.20133720036
[pregnancy and functional disorders of the thyroid gland]. 20133719755
[modification of tear film break-up time by hormonal contraceptives]. 20133710337
infant mortality decline in malaysia, 1946-1975: the roles of changes in variables and changes in the structure of relationships.this analysis has identified several factors contributing to the dramatic decline in infant mortality since world war ii in malaysia, as well as one factor that prevented the infant mortality rate from declining even more rapidly. our main findings are the following: on average, mothers' education more than doubled over the study period, contributing to the decline in their infants' mortality. in addition, the beneficial effect of mothers' education on infant survival appears to have become stro ...20133709892
[experimental hypovitaminosis d in guinea pigs administered different amounts of vitamin c].the experimental model of d-hypovitaminosis is first obtained on guinea pigs. it is established that the least degree of its manifestation is determined under conditions of the optimal supply of the organism with vitamin c. the necessity of using ascorbic acid in a complex of rachitis prophylaxis measures is substantiated.19863705209
[relationship between microflora of the upper small intestine and steatorrhoea in patients with extensive gastric resection]. 20133694857
a new autosomal dominant craniofacial deafness syndrome.a jewish family is reported in which the proband and her father had congenital hearing loss and unusual facies consisting of facial asymmetry, temporal alopecia with frontal bossing, a broad nasal root and small nasal alae. in addition, both were born with a short frenulum of the tongue. we believe these findings represent a new autosomal dominant deafness syndrome with distinct craniofacial features.20133690878
[successful chemotherapy with adriamycin and methotrexate in a case of advanced transitional cell carcinoma of the ureter--a clinical application of subrenal capsule assay].a case of advanced transitional cell carcinoma of the left ureter was treated with a combination of adriamycin and methotrexate. these drugs were selected using the subrenal capsule assay for which tumor tissues were obtained from a biopsy specimen of the left supraclavicular lymph node. complete regression of left supraclavicular lymph node metastasis and 90% regression of para-aortic lymph node metastasis were obtained after four courses of the combination therapy. subsequently, left total nep ...20133688896
health risks among submarine personnel in the u.s. navy, 1974-1979.this study evaluated health risks associated with u.s. navy submarine duty by comparing hospitalization rates of submariners with surface ship personnel. the groups were compared using age-adjusted hospitalization rates for 16 major diagnostic categories and several specific diagnoses postulated to be submarine associated. submarine personnel did not have significantly higher hospitalization rates for any diagnostic categories nor for any of the submarine-associated illnesses. submariner relativ ...20133686743
effect of prostaglandin e1 on deposition of autologous labelled platelets onto human atherosclerotic lesions in vivo.the effects of infusions of prostaglandin e1 (pge1) on platelet deposition at atherosclerotic sites in vivo in man have been examined. thirteen patients with atherosclerotic vascular disease received intravenous pge1 25 mg/kg/min for 6 hours daily for 5 days. prostaglandin e1 had no effect on platelet uptake at atherosclerotic sites but prolonged platelet half-life significantly (p less than 0.001).19873684830
sensitivity and criterion effects in the spatial cuing of visual attention. 20133684496
delayed spontaneous alternation in purkinje cell degeneration mutant mice.purkinje cell degeneration (pcd) mutant mice lose cerebellar purkinje cells. it was found that pcd mice, contrary to normal mice, did not alternate spontaneously at any of 3 inter-trial intervals (15 s, 3 or 6 min). deficits in spontaneous alternation are typical of animals with brain damage in areas important in spatial learning. results are discussed in terms of a role for the cerebellum in spatially mediated behavior and behavioral inhibition.20123683990
the measurement of heart size in the antero-posterior chest radiograph.a computed tomography model was used in eight patients to show how the heart diameter and cardiothoracic ratio might change between antero-posterior and postero-anterior positions. results were compared with measurements made on erect antero-posterior chest radiographs taken on 103 patients without cardiac failure (controls) and 106 with cardiac failure. an upper limit of cardiothoracic ratio of 55% and of heart diameter of 165 mm in males and 150 mm in females was shown to provide useful discri ...20133676657
[rectal bladder. evaluation of its tolerance]. 20133674992
perceptual and behavioural effects of immobility and social isolation in hospitalized orthopedic patients. 20133644253
promoting informed consent of women in labor.laboring women are increasingly being asked to participate in perinatal research. these women should be considered captive or special subjects who deserve greater protection of their rights. essential elements of informed consent are reviewed. specific guidelines are suggested for promoting informed consent for women in labor participating in clinical research.19863639933
cardiovascular response to sudden strenuous exercise.cardiac responses to sudden strenuous exercise were studied in seven dogs instrumented to measure cardiac output (q), stroke volume (sv), left ventricular (lv) pressure, aortic pressure and circumflex coronary blood flow (cbf). the dogs were run on a treadmill at 12.9 km/h, 20% grade for 15s without prior warm-up. during the first 10s of the run, hr and q increased rapidly. by 2s, myocardial o2 requirements, as estimated from either the tension time index (tti) or calculated wall tension, had in ...19873632566
[various aspects of the pathogenesis, clinical picture and treatment of migraine].in a series of 108 patients with migraine the authors studied the characteristics of the emotional-personality sphere and autonomic nervous system, as well as the status of the brain nonspecific systems. the findings of nocturnal electropolygraphy were also used in the study. the efficacy of drugs with antiserotonin action versus multiple modality therapy was compared. the observed disorders in the psychic, autonomic and endocrine systems are interpreted as a consequence of dysfunction of the ce ...20123630504
[various aspects of the pathogenesis, clinical picture and treatment of migraine].in a series of 108 patients with migraine the authors studied the characteristics of the emotional-personality sphere and autonomic nervous system, as well as the status of the brain nonspecific systems. the findings of nocturnal electropolygraphy were also used in the study. the efficacy of drugs with antiserotonin action versus multiple modality therapy was compared. the observed disorders in the psychic, autonomic and endocrine systems are interpreted as a consequence of dysfunction of the ce ...20123630504
bronchial obstruction caused by a solitary endobronchial non-hodgkin lymphoma. 20133622663
monte carlo study of electron spectra produced in semi-infinite and finite water phantoms irradiated by photons of energies up to 2 mev.a monte carlo calculation for the initial electron energy spectra produced in semi-infinite and finite water phantoms irradiated by photons of energies up to 2 mev and photons from 60co are presented incorporating successive compton scattering, photoelectric absorption and auger effect. the backscattering of photons through the top of the phantom and transmission of photons out of the finite phantom through the sides also are considered. the results are compared with the earlier calculation for ...20133610642
alcohol and the brain: neuropsychological correlates. 20133597943
ethanol-induced inhibition of testosterone biosynthesis in vitro: lack of acetaldehyde effect.acute ethanol intake has been shown to decrease plasma testosterone levels in rodents and man. this is mainly due to inhibition of testosterone synthesis, but there is still some controversy about the mechanisms responsible for the inhibition. these mechanisms were studied in the present experiments with isolated rat leydig cells. leydig cells were incubated for two hours in sealed plastic vials with various concentrations of ethanol (0.3-40 mm) or acetaldehyde (5-40 microm). very low ethanol co ...19873593480
the illusion of catch-up growth in premature infants. use of the growth index and age correction.growth data of 61 premature infants who were observed for 29 months were analyzed to determine if there is validity to the concept of catch-up growth. weight, length, and head circumference were recorded at each visit. for each measurement, a growth index was calculated to facilitate comparison of infants of different ages and sexes. the age of a child at each visit was also corrected for prematurity by subtracting the number of weeks premature from the postnatal chronological age to generate a ...20123578164
fine structure of the organic matrix of human pancreatic stones.pancreatic stones that were removed from the pancreatic ducts of patients with chronic calcifying pancreatitis were decalcified so the organic matrix could be studied by scanning and transmission electron microscopy. the observations made by scanning electron microscopy were compared with those made on undecalcified stones, and the findings were correlated with light microscopic observations. after the calcium carbonate was removed, the stones consisted of multiple partitions arranged like a spo ...19863575306
tobacco's radiation: its sources and potential hazards. 20133574847
choice of techniques in nasal repairs.the authors after classifying skin loss of the nose according to their size and site, resume the techniques they normally use in every kind of loss. they suggest those most reliable and easy to perform.20123557208
the silk wrap technique for composite bonding. 20133554047
age-related changes in postprandial plasma glucose, insulin, and free fatty acid concentrations in nondiabetic individuals.plasma glucose, insulin, and free fatty acid (ffa) concentrations were measured from 0800 to 1600 hours in 40 nondiabetic individuals, separated into younger (38 +/- 1.4 years) and older (64 +/- 1.5 years) age groups. meals were served at 0800 (20% total daily calories) and 1200 h (40% of total daily calories), and blood drawn just before the 0800 hours meal and at hourly intervals thereafter until 1600 hours. statistical evaluation of the results of these measurements indicated that day-long pl ...20123546468
incidence of fetal alcohol syndrome and economic impact of fas-related anomalies.the world-wide incidence of the fetal alcohol syndrome (fas) is 1.9 per 1000 live births. incidence rates vary considerably, however, depending on study site. mental retardation is a cardinal feature of fas and is now recognized as the leading known cause of mental retardation in the western world. conservatively estimated for the united states, the economic cost associated with fas-related growth retardation, surgical repair of organic anomalies (e.g. cleft palate, tetralogy of fallot), treatme ...20123545731
interferon in renal cell carcinoma. the ucla experience.three sequential studies of alpha interferon were performed in a total of 84 evaluable patients with metastatic renal cell carcinoma. in study i, conducted from 1981 to 1982, 43 patients received human leukocyte alpha interferon (ifn alpha) 3 x 10(6) u/day, 5 days per week for 12 weeks. in study ii, performed in 1983, vinblastine (0.1 mg/kg/week) was added to the same ifn alpha regimen in 22 subjects. study iii, held from 1984 to 1985, evaluated the effects of escalating doses of interferon alfa ...19873542184
insulin stimulates cord blood erythroid progenitor growth: evidence for an aetiological role in neonatal polycythaemia.polycythaemia in the neonate is a serious pathologic entity which occurs particularly in infants of diabetic mothers (idm) and small-for-gestational age (sga) infants. both of these conditions are associated with fetal hyperinsulinaemia. cultures of cord blood mononuclear cells from polycythaemic idm showed increased growth of late erythroid progenitor colonies, compared to cord blood mononuclear cells from non-polycythaemic infants, reflecting a possible expansion of this progenitor population ...19863539174
physiology and pathophysiology of the colonic circulation.there is growing evidence that colonic blood flow is controlled by both intrinsic and extrinsic factors. the existence of intrinsic vascular control mechanisms is evidenced by pressure-flow (and oxygen uptake) autoregulation, reactive hyperemia, vascular responses to acute venous hypertension, and a functional hyperemia. although myogenic factors have long been considered to be solely responsible for the intrinsic ability of the colon to regulate its blood flow, recent developments indicate that ...19863536216
tooth loss, mastication, and nutrition: an overview. 20123510240
[cigarette smoking and lung metabolism--effects of cigarette smoking on plasma levels of complement c3a and c5a in rabbits]. 19873500346
a common mechanism of chromosomal translocation in t- and b-cell neoplasia.the chromosomal breakpoint involved in the t(8;14)(q24;q11) chromosome translocation in the skw-3 cell line, which directly involves the 3' flanking region of the c-myc gene, was cloned and sequenced. the breakpoint on chromosome 8 mapped to a position 3 kb 3' of c-myc while the chromosome 14 breakpoint occurred 36 kb 5' of the gene for the constant region of the alpha chain of the t-cell receptor (tcr). the translocation resulted in a precise rearrangement of sequences on chromosome 8 and what ...19863490692
relationships between pulmonary inflammation, plasma transudation, and oxygen metabolite secretion by alveolar macrophages.we have previously shown that alveolar macrophages from normal rabbit lungs do not synthesize reactive oxygen intermediates unless first conditioned by culture in vitro in the presence of serum for 24 to 48 hr. this conditioning process is mediated by a serum constituent that partitions on gel exclusion columns with an apparent m.w. of 30,000 to 50,000 daltons. alveolar macrophage conditioning in vitro requires protein synthesis, is associated with the generation of membrane nadph oxidase activi ...19863486910
abnormal distribution of t cell subsets in athymic mice. 20123486898
[insurance (third party) dental health care over the years 1981-1985. trends in the private dental health care sector]. 20123484133
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