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diversity of wolbachia pipientis strain wpip in a genetically admixtured, above-ground culex pipiens (diptera: culicidae) population: association with form molestus ancestry and host selection patterns.analysis of molecular genetic diversity in nine marker regions of five genes within the bacteriophage wo genomic region revealed high diversity of the wolbachia pipentis strain wpip in a population of culex pipiens l. sampled in metropolitan chicago, il. from 166 blood fed females, 50 distinct genetic profiles of wpip were identified. rarefaction analysis suggested a maximum of 110 profiles out of a possible 512 predicted by combinations of the nine markers. a rank-abundance curve showed that fe ...022679853
decapitation improves detection of wolbachia pipientis (rickettsiales: anaplasmataceae) in culex pipiens (diptera: culicidae) mosquitoes by the polymerase chain reaction.polymerase chain reaction (pcr) is often used to detect microorganisms, pathogens, or both, including the reproductive parasite wolbachia pipientis (rickettsiales: anaplasmataceae), in mosquitoes. natural populations of culex pipiens l. (diptera: culicidae) mosquitoes are infected with one or more strains of w. pipientis, and crosses between mosquitoes harboring different wolbachia strains provide one of the best-known examples of cytoplasmic incompatibililty (ci). when we used pcr to monitor wo ...023025192
detection of wolbachia pipientis, including a new strain containing the wsp gene, in two sister species of paraphlebotomus sandflies, potential vectors of zoonotic cutaneous leishmaniasis.individual, naturally occurring phlebotomus mongolensis and phlebotomus caucasicus from iran were screened for infections with the maternally inherited intracellular rickettsia-like bacterium wolbachia pipientis via targeting a major surface protein gene (wsp). the main objective of this study was to determine if w. pipientis could be detected in these species. the sandflies were screened using polymerase chain reaction to amplify a fragment of the wolbachia surface protein gene. the obtained se ...023828002
genomic evolution of the pathogenic wolbachia strain, wmelpop.most strains of the widespread endosymbiotic bacterium wolbachia pipientis are benign or behave as reproductive parasites. the pathogenic strain wmelpop is a striking exception, however: it overreplicates in its insect hosts and causes severe life shortening. the mechanism of this pathogenesis is currently unknown. we have sequenced the genomes of three variants of wmelpop and of the closely related nonpathogenic strain wmelcs. we show that the genomes of wmelcs and wmelpop appear to be identica ...024190075
[studies on the dermotoxins of the 6 clostridium welchii types in rabbits]. 19654287430
effect of hypophysectomy and adrenalectomy on enzymes concerned with nicotinamide adenine dinucleotide synthesis. 19674292487
a new pneumococcus type. type 12a. 19674383090
long-term total parenteral nutrition with growth, development, and positive nitrogen balance. 19684968812
experimental variola in monkeys. i. studies on disease enhancing property of cortisone in smallpox. a preliminary report. 19684979039
[on the pathogenesis of experimental calciphylaxis of salivary glands]. 19694895236
the development of a rest chair profile for healthy and notalgic people. 19694241558
the distribution of tamm horsfall mucoprotein (uromucoid) in the human nephron. 19694906366
[studies on the direct bonding of the orthodontic resin bracket to the tooth enamel. 2. the effect of pretreatment on the enamel surface]. 19694906741
combination chemotherapy in accelerated phase of chronic granulocytic leukemia. 19694303268
[cytotoxicity of silica dust and mixed dust for guinea pig alveolar macrophages in vitro. attempt at quantitative estimation]. 19694323257
human growth hormone and hypopituitargrowth retardation. 19694898810
[salmonella infections, with special reference to carrier state]. 19704988175
foam cells of rabbit atheromatous lesion. identification and cholesterol uptake in isolated cells. 19714331666
effect of phenobarbital on bile flow and bile salt excretion in the rat. 19714253069
interaction of genes controlling ultraviolet sensitivity in neurospora crassa.two independently segregating ultraviolet (uv) sensitivity genes in neurospora crassa interact synergistically resulting in uv sensitivity approximately twice that expected based on an evaluation of the sensitivities of the individual mutants. the mutant genes singly and together reduce photoreactivation (pr) in vivo although a pr enzyme is produced which exhibits normal activity in vitro.19724263406
the isolation of erythrocyte membrane proteins in aqueous media. 19724199550
problems in the detection of the oncogenic potential of viruses or cell cultures. 19724349823
enzymatic methylations. ii. in vitro inhibition of trna and protein methylation by nicotinamide and isonicotinic acid hydrazide: activation of a s-adenosylmethionine-splitting enzyme in rat liver. 19724261254
agglutination of african primate and rodent erythrocytes by adenoviruses, reoviruses, and enteroviruses.african nonhuman primate and rodent erythrocytes were tested for agglutination by adenoviruses, reoviruses, and enteroviruses. squirrel erythrocytes were agglutinated by reovirus serotypes and adenovirus types 3, 11, 16, and 21. adenoviruses also agglutinated brazza monkey erythrocytes to the same titers as those obtained with either rhesus or grey monkey cells. prototype reovirus types 1 and 2 agglutinated grey monkey erythrocytes to much lower titers than either squirrel or human group o red c ...19724631106
[a tentative experimental analysis of upright posture]. 19725028037
a computer for the calculation of skeletal muscle vascular resistance. 19724652900
[sequence of amebic hepatic lesions in the rabbit]. 19724349095
human skeletal muscle phosphorylase activities with exercise and training. 19724640795
[experimental studies for the fluorochroming of human spermatozoa with special reference to so-called vital fluorochroming]. 19724651092
studies of phospholipid-requiring bacterial enzymes. 3. purification and properties of uridine diphosphate glucose:lipopolysaccharide glucosyltransferase i. 19724553445
[effect of humoral antibodies on the rejection of renal transplants]. 19724572549
effect of weak acids on amino acid transport by penicillium chrysogenum: evidence for a proton or charge gradient as the driving force.a variety of weak acids at and below their pk(a) are potent inhibitors of transport in penicillium chrysogenum. the effective compounds include sorbate, benzoate, and propionate (common antifungal agents), indoleacetate (a plant hormone), acetylsalicylate (aspirin), hexachlorophene, and a yellow pigment produced by the mycelia under nutrient-deficient conditions, as well as the classical uncouplers 2,4-dinitrophenol, p-nitrophenol, and azide. the results suggest that a proton gradient or charge ...19734632394
study of albumin synthesis in relation to urea synthesis. 19734746768
alterations in cerebral protein-synthesizing systems during maturation. 19734802996
[functional changes of the thyroid and adrenal glands in the course of immunological reactions]. 19734144094
[the teratogenic effect of busulfan on testis cells of the fetal rat]. 19734800446
proceedings: correlation of androgenic activities of the lower testosterone esters in rat, with rm values and hydrolysis rates. 19734150536
immunohistochemistry of liver in alpha1-antitrypsin deficiency. a comparative study. 19744137719
gamma-aminobutyric acid: drug-induced elevation in monkey brain. 19744153580
rate of thrombin-fibrinogen reaction in some mammalian species. 19744213348
importance of sperm capacitation for gamete contact in the rabbit. 19744413787
importance of sperm capacitation for gamete contact in the rabbit. 19744413787
correlation of c-type virus (wf-1) production and heme synthesis in a rat fibroblastic cell line. 19744360116
[abortive infections produced by myxoviruses and rhabdoviruses and their possible causes]. 19744374832
letter: influenza virus vaccination and renal transplant rejection. 19744595178
ionic effects on the motility of bull and chimpanzee spermatozoa. 19744413987
the effect of magnesium deficiency on serum aldosterone in rats fed two levels of sodium. 19751196006
[effects of combination alfaxalone and alfadolone, anesthetic derivatives of pregnanedione, on cerebral hemodynamics in cats].intravenous injection of ct 1341 (a mixture of alphaxalone and alphadolone dissolved in cremophor el) induced a decrease in cerebral blood flow (cbf) measured by 133xe clearance in cats with artificial respiration (the mean reduction in cbf was 2 ml/100 g/mn for 1,2 mg/kg or ct 1341. so, cbf was decreased by 22% when ct 1341 (7,2 mg/kg) was intravenously injected, (mean pa co2 equals 30 mm hg). changes in cbf following ct 1341 intravenous injection seems to be caused by cerebral vascular constri ...1975126719
comparative morphology of genital cones of genus ancylostoma dubini, 1843.male worms of ancylostoma braziliense, a. ceylanicum, a. kusimaense, a. malayanum, a. duodenale, a. caninum, a. tubaeforme, agriostomum vryburgi and cyclodontostomum purvisi have the external appendages beside the anogenital aperture. these anogenital structures are morphologically similar and are assumed to be homologous among the species with three pairs of teeth or more. in hookworms with two pairs of teeth, the anogenital structures are complex. anogenital features can be used as a taxonomic ...19751166351
changes in monoamine oxidase and monoamines with human development and aging.a series of studies of monoamines and their metabolism in a variety of human tissues indicate that there are aging effects that may alter neurotransmitter substances. monoamine oxidase (mao) activity has a significant positive correlation with age in plasma and blood platelets of normal subjects and patients suffering from depressive disorders. monoamine oxidase and age correlate positively in hindbrain and in eight separate ares of human brains from patients who died from a variety of causes. h ...19751088942
an electromyographic study of uterotubal activity in the ewe.the electrical activity of the oviduct and uterus was automatically registered on a potentiometric pen recorder in ewes fitted with an extracellular multielectrode assembly. the duration and amplitude of local non-propagating activity of the uterus increased and became progressively grouped into phases as natural oestrus progressed. phases of contractions lasting 5-6 min were initially propagated at a rate of 2/hr. their frequency increased within 24 hr of the decline in plasma progesterone leve ...197660491
tissue fractionation in neurobiochemistry: an analytical tool or a source of artifacts. 197722511
ultrastructural localization of calcium around the membrane of the surface connected system in the human platelet.the localization of calcium in the membrane system of human platelets was determined by ultrahistochemical methods equipped with an electron probe x-ray microanalyzer. after potassium oxalate-glutaraldehyde treatment large amounts of electron opaque precipitates were observed around the membrane of the surface connected system. electron probe x-ray microanalysis clearly defined that the precipitates were composed of calcium oxalate. the localization of calcium on the membrane of the surface conn ...197896043
proceedings of the fifteenth congress of the european dialysis and transplant association, istanbul, turkey, 1978. 197833380
the ultrastructure of the rickettsia-like microorganism wolbachia pipientis and associated virus-like bodies in the mosquito culex pipiens. 1978671578
origin and early development of canine circumanal glands. 1979517821
[intravenous cholangiography in hyperbilirubinaemia (author's transl)].the effect of bilirubin on biliary and renal excretion of methylglucamine-iodipamide at an infusion rate of 1.3, 2.6 and 5.2 mu mol/min/kg was studied by intravenous injection into five dogs with normal liver functions and chronic duodenal fistulas. unconjugated bilirubin administered in a dose of 0.1 mu mol/min/kg reduced biliary iodipamide excretion and concentration significantly, but did not affect renal contrast material excretion. this indicates that the unsatisficatory radiological result ...1979153309
guinea pig transfer factor: restriction of macrophage migration inhibitory activity to extraordinary dilution confirmed with demonstration of diminished potency of stored preparations. 197988292
an evaluation of three new commercial peptones used in some nutrient media designed for the isolation and characterization of pathogenic vibrios. 1979262509
persistence of ketosis despite suppression of lipolysis by 16,16-dimethylprostaglandin e2 in experimental diabetic ketoacidosis in rats. 1979113273
serial prolactin and thyrotropin responses to thyrotropin-releasing hormone throughout normal human pregnancy. 1979107178
a rickettsia-like microorganism similar to wolbachia pipientis and its occurrence in culex mosquitoes. 19836863975
reproduction of an inbred strain of culex pipiens prevented by loss of wolbachia pipientis. 19836404990
[proportions of the femur and humerus in relation to bone length].taking as a starting point the known fact that the vertical proportions of man are dependent upon stature, a study has been made to investigate if the relations between individual segments of long tubular bones are also dependent upon overall bone length. for these investigations, use was made of 356 human femurs of unknown sex, which were obtained from the bone collection of the institute of anatomy (kurp 1979), and 70 human humeri of known sex (kropf 1979), which were obtained from the institu ...19854073525
hypercalcemia in the neuroleptic malignant syndrome.the neuroleptic malignant syndrome (nms) developed in a 32-year-old man following fluphenazine enanthate administration. hypercalcemia was initially present, perhaps reflecting release of calcium from skeletal muscle stores. the elevated serum calcium levels support the existence of a peripheral muscle abnormality in the pathogenesis of the nms and provides another point of similarity between nms and malignant hyperthermia.19853970627
selective regulation of carboxypeptidase peptide hormone-processing enzyme during enkephalin biosynthesis in cultured bovine adrenomedullary chromaffin cells.bovine adrenomedullary chromaffin cells in culture were incubated with reserpine or forskolin, two agents acting through different mechanisms, which increase cellular [met]enkephalin levels by 2-fold after 72 h. cells were harvested and chromaffin granules were purified on a linear sucrose gradient. after reserpine treatment, carboxypeptidase-processing enzyme specific activity in chromaffin granule fractions was stimulated 1.9-fold, and co2+-stimulated carboxypeptidase specific activity was sti ...19854039723
extravasation of polymorphonuclear leukocytes from the cerebral microvasculature. inflammatory response induced by alpha-bungarotoxin.postcapillary venules represent the segment of the microvasculature most vulnerable to inflammatory processes. while there is a considerable body of data on the peripheral vasculature, little is known about the primary events occurring during inflammatory reactions in cerebral blood vessels. we introduce here a model by which the migration of polymorphonuclear leukocytes through the cns endothelial barrier can be studied. alpha-bungarotoxin is used as a chemotactic agent and is shown, for the fi ...19854053172
dyschondroplasia/osteochondrosis of the femoral trochanter in the fowl.of 104 lame broilers, 12 birds with femoral trochanteric abnormalities were identified by post-mortem and radiographic examination. defects occurred in ossification of either the trochanteric zenith or its medial aspect. lesions were identified as dyschondroplasia, osteochondrosis or osteochondrosis dissecans affecting the articular surface of the femoral trochanter. in the absence of concomitant musculoskeletal disease, degrees of lameness can be attributed to trochanteric lesions. breaches in ...19854031131
identification of two cases of bovine undifferentiated tumours (squamous cell carcinoma and adenocarcinoma) by electron microscopy.two cases of undifferentiated tumours were found in cows. electron microscopy revealed that one was an undifferentiated squamous cell carcinoma of unknown primary site and the other an undifferentiated adenocarcinoma of the lung.19853837797
enhanced responsiveness of the coronary blood vessel of the dog heart-lung preparation to pgi2 after chronic chemical sympathectomy.chronic chemical denervation of the sympathetic nervous system with 6-oh dopamine resulted in an augmentation of the coronary blood flow (cbf) increase inherent in the canine heart-lung preparation, but not in an augmented accumulation of 6-keto pgf1 alpha in the circulating blood. in denervated hlp, 6-keto pgf1 alpha was lower and the vasodilator response to pgi2 larger at the start of the experiments. it was concluded that exaggerated increase in cbf was due to a potentiation of the vasodilato ...19853932732
legionella in power station cooling waters. 19852862486
diversity and structure of genes of the alpha family of mouse t-cell antigen receptor.we have analysed 19 complementary dna clones encoding the alpha-chain of the t-cell antigen receptor derived from thymic transcripts, and find that 15 of them contain partial or complete variable (v alpha) genes. seven of these genes cross-hybridize to over 40 germline v alpha gene segments in southern blot analyses. of the 19 joining (j alpha) sequences examined, 18 seem to be encoded by distinct gene segments, hence the repertoire of j alpha gene segments is much larger than those of the immun ...19853839904
stoichiometry and kinetics of the interaction of prostaglandin h synthase with anti-inflammatory agents.we have examined the kinetics, stoichiometry, and chemical nature of the interaction of three anti-inflammatory agents (indomethacin, flurbiprofen, and meclofenamic acid) with pure ovine prostaglandin h synthase. the kinetics of the interaction with the synthase for each of the three agents, monitored by the decrease in cyclooxygenase activity, was consistent with the model proposed by rome and lands (rome, l.h., and lands, w.e.m. (1975) proc. natl. acad. sci. u.s.a. 72, 4863-4865): a rapid and ...19853930499
injections of atropine into the caudate nucleus impair the acquisition and the maintenance of passive avoidance.two experiments were performed to test the hypotheses that cholinergic activity of the caudate nucleus (cn) is involved in the acquisition and in the maintenance of passive avoidance behavior. rats were trained, in one trial, to avoid one of two compartments of a conditioning box and retention of the task was measured 24 hours later. several doses of atropine were injected into the cn of independent groups of animals. in experiment 1 the atropine was injected 2 minutes after training and in expe ...19853983217
excretion of radioactivity in faeces and urine of rats injected with 3h,14c-lipopolysaccharide.the route of excretion of lipopolysaccharide (lps) and its possible degradation in vivo was studied in rats using biosynthetically radiolabelled lps from salmonella abortus equi, carrying 3h activity exclusively in fatty acids and 14c activity in fatty acids and sugars. following intravenous injection of the above lps in as2 rats with or without anaesthesia, excretion of radioactivity occurred mainly in the faeces and to smaller extent in urine. the rate of excretion was slow, a large part of th ...19854005148
trends in cancer mortality in italy, 1955-1978.trends in age-specific and age-standardized cancer death certification rates in italy from 1955 to 1978 were analyzed. in males total cancer mortality rates increased in all age groups. however, when respiratory and other tobacco-related neoplasms were excluded, death certification rates were roughly stable up to age 64. moderate decreases in overall cancer mortality have been apparent at younger ages (35-44) since the early 1970's. in females, all the age-specific and the age standardized, unde ...19854024279
immunization and immunosuppression in mice reared for high or low immune responsiveness against nematospiroides dubius. 19854030203
[sequential histochemical studies of the esophageal carcinoma in rats induced by n-methyl-n-amylnitrosamine]. 19854032830
tabulation and assessment of 113 human surveillance cytogenetic studies conducted between 1965 and 1984.there is an increasing tendency to monitor human exposure to genotoxic chemicals by the assessment of chromosomal aberrations or sister-chromatid exchanges (sces) in peripheral blood lymphocytes. in order to assess the sensitivity of these techniques, and to discern minimal criteria for their conduct, a survey of 113 human lymphocyte cytogenetic surveillance studies conducted between 1965 and 1984 has been undertaken. the present survey indicates the urgent need for standardization of study prot ...19854033683
protein antigens of encapsulated klebsiella pneumoniae surface exposed after growth in the presence of subinhibitory concentrations of cephalosporins.it recently has been reported by us that cephalosporins, at a concentration below that influencing growth rate, reduced the production of enterochelin and capsule formation of iron-depleted klebsiella pneumoniae. we now report on the antigenicity of the outer membrane components and surface-exposed protein antigens of iron-depleted cells grown in the presence or absence of cephalosporins. all major outer membrane proteins, including iron-regulated membrane proteins, were immunogenic. encapsulate ...19853914857
copper deficiency in infants fed cow milk. 19853998919
preferential uptake of intravenously administered hyaluronidase (hyalosidase) by damaged rat myocardium.the induction of myocardial infarction in rats by ligation of the left-anterior coronary artery was confirmed by measurement of increased plasma levels of creatine kinase, aspartate aminotransferase and lactate dehydrogenase. using this model system it has been established that intravenous administration of 125i-labelled hyaluronidase to rats resulted in a preferential uptake of the enzyme by damaged myocardium as compared to normal heart tissue.19854027352
multilayer-enzyme linked immunosorbent assay (ml-elisa) for detection of entamoeba histolytica trophozoite coproantigen.multilayer elisa (ml-elisa) method for entamoeba histolytica trophozoite coproantigen was developed for diagnosis of amoebiasis and its usefulness vis-a-vis microscopic examination analysed for paired specimens from 87 patients from lucknow and hyderabad, india. all the stool specimens positive for trophozoites were also found to be positive in ml-elisa. out of a total 32 samples positive for cysts in microscopy 21 (65.62%) gave positive reactions for coproantigen. results on 26 samples drawn fr ...19852867033
identification of apolipoproteins involved in the interaction of human high density lipoprotein3 with receptors on cultured cells.human high density lipoprotein (hdl), devoid of apolipoproteins e or b, binds with high affinity and specificity to cultured cells derived from several tissues. in order to investigate the ligand specificity of the putative receptor, we have performed competitive inhibition studies to identify the components of high density lipoprotein that bind to cell surfaces of rat adrenal cortical cells and human skin fibroblasts. radiolabeled hdl3 was displaced with unlabeled apolipoprotein-dimyristoylphos ...19852982866
studies on the mechanism of action of omeprazole.the effects of omeprazole on preparations of pig gastric (h+ + k+)-atpase have been studied. omeprazole was found to inhibit the (h+ + k+)-atpase activity in a time-dependent manner. inhibition was more pronounced at ph 6.1 compared with ph 7.4 and decreased as the concentration of (h+ + k+)-atpase preparation increased. the potency of omeprazole was therefore highly dependent upon the conditions used. when pre- incubated with (h+ + k+)-atpase preparation (30 micrograms protein/ml) for 30 min at ...19852992525
[the effect of intraperitoneal administration of isoprenaline on atpase activity in the brain of rats of different ages]. 19853155871
thio-analogues of inorganic pyrophosphate inhibit the replication of influenza virus a in vitro.mono- and bisthiopyrophosphate can inhibit the replication of influenza virus a/x49 in madin-darby canine kidney (mdck) cells at concentrations at which no cytotoxic effect is observed after 3 days. the thiopyrophosphate analogues inhibit the rna transcriptase activity of this virus possibly by chelating with an essential metal ion in the transcriptase complex. [31p]nmr spectroscopy indicates that bisthiopyrophosphate coordinates to zinc through sulphur and magnesium through oxygen which may inf ...19852990333
physiology and pathophysiology of the colonic circulation.there is growing evidence that colonic blood flow is controlled by both intrinsic and extrinsic factors. the existence of intrinsic vascular control mechanisms is evidenced by pressure-flow (and oxygen uptake) autoregulation, reactive hyperemia, vascular responses to acute venous hypertension, and a functional hyperemia. although myogenic factors have long been considered to be solely responsible for the intrinsic ability of the colon to regulate its blood flow, recent developments indicate that ...19863536216
[requirement of cyclic 3',5'-monophosphate in the production of a permeability increasing factor by vibrio cholerae]. 19863018312
[osmotic resistance of erythrocytes in cattle]. 19863087113
cellular distribution of lysosomal hydrolase activities in the regenerating rat liver.cathepsins b and d, beta-galactosidase, and acid phosphatase activities were found to be decreased in the regenerating rat liver, the reduction being maximal around the peak of hepatocyte mitoses (30 h). to investigate whether these changes could be heterogeneously distributed among hepatic cells, total cell populations from control or two-thirds hepatectomized rat livers were dissociated by the collagenase perfusion technique and analysed by different procedures. isopycnic centrifugation in a m ...19863089641
effects of total parenteral nutrition on the development of intestinal endotoxemia in rats: a comparison between glucose and lipid.the effects of parenteral nutrition (pn) and of the difference in the pn regimens between glucose and lipid emulsion on the development of endogenous endotoxemia were studied in 40 wister rats. endotoxemia was induced by occluding the superior mesenteric vein (smv) for 30 min. the plasma endotoxin in the portal blood at the time of the release of the smv occlusion and that in the arterial blood 10 min after the release were quantified. twenty of the 40 rats had received pn for 48 hr prior to the ...19863091866
phosphoenolpyruvate carboxykinase as a selective indicator of ochratoxin a induced nephropathy. 19862881768
dose-related effects of synthetic human beta-endorphin and naloxone on fed gastrointestinal motility.in humans, plasma beta-endorphin levels rise during application of acute stressful stimuli (vertigo, cold pain, and transcutaneous electrical stimulation) that induce gut motor disturbances. whereas it is possible that circulating beta-endorphin participates in the mediation of these central effects on gut motility, its role cannot be established solely on the basis of changes in plasma levels. therefore, we designed the present study to investigate 1) the dose-related effects of intravenous syn ...19862942039
structure-activity relationships of sex steroid analogs determined in vitro in a thyroid hormone-responsive membrane ca2+-atpase model.physiological concentrations of l-t4 were found previously to stimulate ca2+-atpase activity in vitro in reticulocyte membranes from female rabbits and to inhibit this enzyme in reticulocyte membranes from males. in these previous studies, preincubation of intact cells or ghosts with testosterone (5 x 10(-11) m) converted female-source reticulocyte membranes to male-type responsiveness to thyroid hormone (inhibition of ca2+-atpase activity). preincubation of reticulocyte membranes with 17 beta-e ...19862946570
fine structure of the organic matrix of human pancreatic stones.pancreatic stones that were removed from the pancreatic ducts of patients with chronic calcifying pancreatitis were decalcified so the organic matrix could be studied by scanning and transmission electron microscopy. the observations made by scanning electron microscopy were compared with those made on undecalcified stones, and the findings were correlated with light microscopic observations. after the calcium carbonate was removed, the stones consisted of multiple partitions arranged like a spo ...19863575306
insulin stimulates cord blood erythroid progenitor growth: evidence for an aetiological role in neonatal polycythaemia.polycythaemia in the neonate is a serious pathologic entity which occurs particularly in infants of diabetic mothers (idm) and small-for-gestational age (sga) infants. both of these conditions are associated with fetal hyperinsulinaemia. cultures of cord blood mononuclear cells from polycythaemic idm showed increased growth of late erythroid progenitor colonies, compared to cord blood mononuclear cells from non-polycythaemic infants, reflecting a possible expansion of this progenitor population ...19863539174
relationships between pulmonary inflammation, plasma transudation, and oxygen metabolite secretion by alveolar macrophages.we have previously shown that alveolar macrophages from normal rabbit lungs do not synthesize reactive oxygen intermediates unless first conditioned by culture in vitro in the presence of serum for 24 to 48 hr. this conditioning process is mediated by a serum constituent that partitions on gel exclusion columns with an apparent m.w. of 30,000 to 50,000 daltons. alveolar macrophage conditioning in vitro requires protein synthesis, is associated with the generation of membrane nadph oxidase activi ...19863486910
a common mechanism of chromosomal translocation in t- and b-cell neoplasia.the chromosomal breakpoint involved in the t(8;14)(q24;q11) chromosome translocation in the skw-3 cell line, which directly involves the 3' flanking region of the c-myc gene, was cloned and sequenced. the breakpoint on chromosome 8 mapped to a position 3 kb 3' of c-myc while the chromosome 14 breakpoint occurred 36 kb 5' of the gene for the constant region of the alpha chain of the t-cell receptor (tcr). the translocation resulted in a precise rearrangement of sequences on chromosome 8 and what ...19863490692
influence of single neonatal treatment with allylestrenol or diethylstilbestrol on microsomal enzyme activity of rat liver in adulthood.a single neonatal treatment of rats with a steroid (allylestrenol or diethylstilbestrol) did not alter the later activity of the hepatic microsomal (cytochrome p-450) enzyme system, but inhibited the inducer action of another steroid (testosterone) administered at the age of six weeks. this suggests that a hormonal imprinting-like mechanism also operates in the case of enzymes.19863784633
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