Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| [determination of serum immunoglobulin level in patients with immunologic deficiency by thermistography]. | 1999 | 89257 | |
| beta-lactamase inhibitors--a novel approach. | 1999 | 89565 | |
| vitiligo patterns simulating autoimmune and rheumatic diseases. | several variants of generalised vitiligo can be recognised by their cutaneous distribution. in some, certain anatomical regions--e.g., hands--are predominantly affected while the cutaneous depigmentation in other variants shows a similar anatomical distribution to that of the internal structures affected in some of the autoimmune and rheumatic diseases. five patients have been seen, and three described by others, with vitiligo affecting skin of eyelids and lower front of neck, reminiscent of the ... | 1999 | 89452 |
| continuous subcutaneous insulin infusion or subcutaneous insulin injections. | 1999 | 89550 | |
| deaths of infants after triple vaccine. | 1999 | 89408 | |
| peripheral and central 5-hydroxytryptamine in trisomy 21. | 1999 | 93675 | |
| new screening test for colorectal cancer developed in canada. | 1999 | 89207 | |
| diagnostic value of biochemical analysis of pleural effusions. carcinoembryonic antigen and beta 2 microglobulin. | pleural effusions from 105 patients with malignant and nonmalignant diseases were examined for tumor cells, content of cea, beta2 microglobulin, ceruloplasmin, alpha2 macroglobulin, orosomucoid, lysozyme, and hexosaminidase. only cea and beta2 microglobulin determinations were of diagnostic value. cea concentrations greater than 11 ng/ml were found only in malignant effusions. beta 2 microglobulin values were increased in pleural effusions due to lymphoma or immune diseases. measurement of cea a ... | 1999 | 85412 |
| effect on bone of withdrawal of oestrogen therapy. | 1999 | 89300 | |
| frankly speaking: economics: nursing's friend or foe? | 1999 | 96934 | |
| discipline without punishment--part i. | 1999 | 2586930 | |
| preoperative haemoglobin as predictor of outcome of diabetic amputations. | simple factors which may serve as predictors of the success or failure of amputations in the feet were examined in 59 consecutive diabetics. age, sex, method of diabetic control, smoling, presence of neuropathy or peripheral pulses, preoperative blood-urea, and temperature did not correlate with success of amuptations. the average preoperative white-cell count and blood-sugar were higher in the failure group (p less than 0.01 and p less than 0.05 respectively), but there was considerable overlap ... | 1999 | 89280 |
| fatal leishmaniasis in renal-transport patient. | 1999 | 88649 | |
| malabsorption syndrome in ibadan. | 1999 | 97069 | |
| cell communication, cell union, and initiation of meiosis in ciliate conjugation. | 1999 | 97053 | |
| [pathogenesis of pancreatitis (author's transl)]. | 1999 | 96436 | |
| multiple astrocytoma of spinal cord in von-recklinghausen's disease. a case report. | 1999 | 96357 | |
| candida dubliniensis and candida albicans display surface variations consistent with observed intergeneric coaggregation. | adherence of yeasts to other microorganisms and epithelial cell surfaces is important in their colonization. comparative studies based on the coaggregation of candida dubliniensis versus candida albicans with fusobacterium nucleatum and other oral bacteria suggested differences in the surfaces of these yeasts. transmission electron microscopy was used to test the hypothesis that there are morphologic variations in the cell surface of these two species. c. dubliniensis type strain cd36 and c. alb ... | 1999 | 18473545 |
| prevalence of beta-lactamase-producing strains among 149 anaerobic gram-negative rods isolated from periodontal pockets. | in a prospective study, 47 adults presenting a rapidly progressive periodontitis were selected in order to evaluate the prevalence of beta-lactamase-producing strains among oral anaerobic gram-negative rods. predominant anaerobes were identified from two of the deepest periodontal pockets. beta-lactamase-positive strains fulfilled to at least two of three criteria: positive nitrocefin test, penicillin etest minimal inhibitory concentration > 1 microgram/ml, and disk diffusion synergy between amo ... | 1999 | 10895690 |
| periodontopathic bacteria in english hiv-seropositive persons. | selected periodontopathic bacteria were sought in 20 hiv-infected english patients and eight noninfected control subjects with similar periodontal status, using highly specific dna probes. actinobacillus actinomycetemcomitans (a. a), porphyromonas gingivalis, campylobacter rectus, prevotella intermedia, and fusobacterium nucleatum were more frequently detected and were found at higher levels in hiv-infected individuals than in controls. significantly increased levels of treponema denticola but, ... | 1999 | 10842858 |
| bacterial colonisation during gtr treatment. a longitudinal analysis. | the purpose of the present study was to evaluate the long-term biological and clinical effects of a controlled delivery system releasing tetracyclines during the healing of interproximal periodontal defects treated by the technique of guided tissue regeneration (gtr) using e-ptfe membranes. | 1999 | 10768009 |
| comparing periodontal disease in identical twins: a case report. | previous investigators have shown that numerous environmental and genetic variables may contribute to the pathogenesis of periodontal disease. this case report presents clinical and laboratory findings of a set of caucasian female identical twins. one patient presented clinically with mild gingivitis and no clinical or radiographic signs of periodontitis. the other exhibited gingivitis with localized, moderate-to-severe periodontitis. neither patient reported a history of systemic conditions tha ... | 1999 | 10634119 |
| in vitro volatile sulfur compound production of oral bacteria in different culture media. | the purpose of this study was to detect the relative contribution of porphyromonas gingivalis, fusobacterium nucleatum, and prevotella intermedia in the production of oral malodor. | 1999 | 10635291 |
| inflammatory cytokine production and specific antibody responses to lipopolysaccharide from endodontopathic black-pigmented bacteria in patients with multilesional periapical periodontitis. | we examined the induction of the cytokines interleukin (il)-1 beta, il-6, and il-8 by lipopolysaccharides (lpss) from several species of possible endodontopathic black-pigmented bacteria. studies were conducted in human whole blood cultures from six patients (two from each group) with differing numbers of periapical periodontitis lesions (i.e. patients with radiographically clear periapical lesions in 10 or more teeth (high-lesion group, n = 4), in one or two teeth (low-lesion group, n = 6), and ... | 1999 | 10726523 |
| development of a clindamycin-impregnated fiber as an intracanal medication in endodontic therapy. | the effectiveness of traditional endodontic intracanal medications in reducing bacterial numbers and preventing acute flare-ups and pain continues to be questioned. in the present study, a new local delivery device was developed that releases a substantive dose of clindamycin into root canals. clindamycin-impregnated ethylene vinyl acetate (eva) fibers were produced, and the sensitivity of common endodontic microbes to the fibers were established. an in vitro model was developed to persistently ... | 1999 | 10726537 |
| streptococcus viridans intra-amniotic infection associated with antecedent cunnilingus. | introduction of bacteria into the amniotic cavity has been associated with oral sex through an ascending infectious route. previous reports have implicated both capnocytophaga and fusobacterium nucleatum via this process. we report a case of streptococcus viridans intra-amniotic infection occurring at 25 weeks' gestation. patient questioning revealed a close temporal relationship between the onset of symptoms and previous episodes of cunnilingus. the diagnosis of subclinical bacterial colonizati ... | 1999 | 10755795 |
| beta-lactamases producing anaerobic bacteria in dentoalveolar abscesses. | pus samples of 30 patients with closed dentoalveolar abscesses who had not received antimicrobial therapy for at last two months were screened for the presence of beta-lactamase-producing anaerobic bacteria. from these 30 pus samples, a total of 112 bacterial strains were isolated; 83 of them were strict anaerobes and 29 were aerobes. beta-lactamases activity of the selected anaerobic bacteria was tested after identification of the isolates and was detected in 5 of the total 83 (6%) strict anaer ... | 1999 | 10693296 |
| relationship of the subgingival microbiota to a chairside test for aspartate aminotransferase in gingival crevicular fluid. | the aim of the present study was to evaluate the association between the occurrence of certain specific periodontal pathogens and aspartate aminotransferase (ast) levels in gingival crevicular fluid (gcf). | 1999 | 10052771 |
| dominant cross-reactive antibodies generated during the response to a variety of oral bacterial species detect phosphorylcholine. | the intraperitoneal immunization of balb/c mice with subgingival plaque from advanced periodontal pockets or with certain strains of actinobacillus actinomycetemcomitans, fusobacterium nucleatum, actinomyces israelii, streptococcus mitis, or streptococcus oralis yielded frequently indistinguishable igm monoclonal antibodies which were reactive with antigens from a variety of oral bacteria. this study aimed to characterize the specificity of such monoclonal antibodies and the diversity of oral ba ... | 1999 | 10065949 |
| immune response to fusobacterium nucleatum and prevotella intermedia in patients with chronic maxillary sinusitis. | our objective was to study the immune response to 2 anaerobic bacteria in patients with chronic maxillary sinusitis. immunoglobulin g class antibody titers to fusobacterium nucleatum and prevotella intermedia were measured by enzyme-linked immunosorbent assay. serum levels in the patients were determined on the day sinus aspiration for culture was done, and 75 to 90 days later, after completion of antimicrobial therapy, prevotella intermedia was isolated from 16 aspirates, and f. nucleatum from ... | 1999 | 10086624 |
| abscess forming ability of streptococcus milleri group: synergistic effect with fusobacterium nucleatum. | the abscess forming abilities of "streptococcus milleri" strains (streptococcus constellatus, streptococcus anginiosus, and streptococcus intermedius) isolated from dentoalveolar abscesses and the synergistic effect of fusobacterium nucleatum co-inoculated with the isolates were examined on a mouse subcutaneous abscess model. five days after inoculation, all s. milleri strains formed abscesses, which showed less pathological spread to surrounding connective tissues than those formed by staphyloc ... | 1999 | 10338189 |
| effects of hydrogen peroxide on growth and selected properties of porphyromonas gingivalis. | in this study we first evaluated the effects of hydrogen peroxide (h2o2) on growth and selected properties of porphyromonas gingivalis, and compared them with those obtained by a reducing agent (cysteine). the growth of p. gingivalis was only moderately affected when h2o2 was added at concentrations up to 30 mm in a complex culture medium. however, when a defined basal medium was used, h2o2 at a concentration of 3 mm completely inhibited growth of p. gingivalis. incorporation of cysteine at conc ... | 1999 | 10339828 |
| linezolid activity compared to those of selected macrolides and other agents against aerobic and anaerobic pathogens isolated from soft tissue bite infections in humans. | linezolid was tested against 420 aerobes and anaerobes, including 148 pasteurella isolates, by an agar dilution method. linezolid was active against all pasteurella multocida subsp. multocida and p. multocida subsp. septica isolates and most pasteurella canis, pasteurella dagmatis, and pasteurella stomatis isolates. the mic was </=2 microg/ml for staphylococci, streptococci, ef-4b, weeksella zoohelcum, fusobacterium nucleatum, other fusobacteria, porphyromonas spp., prevotella spp., peptostrepto ... | 1999 | 10348773 |
| the effects of histatin-derived basic antimicrobial peptides on oral biofilms. | susceptibility of bacteria to antimicrobial agents is strongly reduced by the formation of complex biofilms. we investigated whether synthetic histatin analogs with broad-spectrum antibacterial activity in vitro were also active against these complex mixtures of bacteria, as present in saliva and plaque. in a simplified model system for dental plaque, hydroxyapatite discs were placed in a continuous culture system comprised of streptococcus mutans, s. sanguis, s. salivarius, actinomyces naeslund ... | 1999 | 10371248 |
| antibiotic susceptibility of putative periodontal pathogens in advanced periodontitis patients. | in the present study, the antibiotic susceptibility of most prevalent micro-organisms in advanced periodontitis patients was evaluated. in 56 patients, pooled subgingival plaque samples were taken from the deepest site of each quadrant and were cultivated anaerobically. from each patient, the 4 most frequently encountered types of bacterial colonies were subcultured and identified (rapid id 32 a). from all bacterial species identified in the 224 subcultures, the 4 most prevalent were used for su ... | 1999 | 10382573 |
| intra-familial distribution of fusobacterium nucleatum strains in healthy families with optimal plaque control. | fusobacterium nucleatum, a gram-negative anaerobic rod associated with periodontal disease, is also found in healthy individuals and is considered part of the indigenous oral microflora. although intra-familial transmission of periodontal pathogens has been documented, there are no data relating transmission of f. nucleatum. this study investigated the distribution of f. nucleatum strains in 4 strictly healthy families. 32 f. nucleatum strains were isolated from 19 individuals (8 parents and 11 ... | 1999 | 10382581 |
| flow cytometry to monitor phagocytosis and oxidative burst of anaerobic periodontopathogenic bacteria by human polymorphonuclear leukocytes. | the reduced susceptibility to phagocytosis found among some periodontopathogenic anaerobes may account for the differences between invasive and non-invasive strains. we applied flow cytometry as a powerful tool to analyze and quantify phagocytosis using standardized cultures of oral anaerobes (porphyromonas gingivalis, prevotella intermedia, p. nigrescens, capnocytophaga gingivalis, c. ochracea, c. sputigena, fusobacterium nucleatum and peptostreptococcus micros) and heparinized whole blood. bac ... | 1999 | 10384401 |
| beta-lactamase production by oral anaerobic gram-negative species in infants in relation to previous antimicrobial therapy. | the frequency of beta-lactamase production in gram-negative bacteria has increased considerably during recent years. in this study, beta-lactamase production by oral anaerobic gram-negative rods isolated from saliva was longitudinally examined for 44 caucasian infants at the ages of 2, 6, and 12 months in relation to their documented exposure to antibiotics. isolates showing decreased susceptibility to penicillin g (1 microg/ml) were examined for beta-lactamase production by using a chromogenic ... | 1999 | 10390208 |
| a 15-month evaluation of the effects of repeated subgingival minocycline in chronic adult periodontitis. | a double-blind, randomized, parallel, comparative study was designed to evaluate the long-term safety and efficacy of subgingivally administered minocycline ointment versus a vehicle control. | 1999 | 10397521 |
| clinical and microbiological effects of initial periodontal therapy in conjunction with amoxicillin and clavulanic acid in patients with adult periodontitis. a randomised double-blind, placebo-controlled study. | the aim of the present study was to investigate the clinical and microbiological effects of initial periodontal therapy in conjunction with systemic amoxicillin plus clavulanic acid in adult periodontitis patients using a double-blind, parallel-group, and placebo-controlled protocol. 21 patients with a clinical diagnosis of generalised adult periodontitis were recruited. clinical measurements and microbiological assessments were carried out at baseline, 3, and 12 months post-treatment. approxima ... | 1999 | 10412851 |
| comparative antimicrobial activity of an essential oil and an amine fluoride/stannous fluoride mouthrinse in vitro. | although laboratory studies are not necessarily predictive of clinical activity; they can help to elucidate mechanisms underlying clinical activity when the latter has been established. in a recent clinical study, an essential oil mouthrinse (listerine antiseptic) was shown to be significantly more effective than an amine fluoride/stannous fluoride mouthrinse (meridol) in inhibiting supragingival plaque formation. this paper reports the results of laboratory studies comparing the antimicrobial e ... | 1999 | 10412853 |
| porphyromonas gingivalis prevalence related to other micro-organisms in adult refractory periodontitis. | forty-six adult periodontal patients, selected on the basis of clinical examination, and 46 adult healthy subjects were examined. the subgingival plaque samples from one inflammatory and one non-inflammatory site of each periodontal patient were studied to determine porphyromonas gingivalis prevalence related to other periodontal micro-organisms and to periodontal tissue destruction. the results showed porphyromonas gingivalis as the main pathogenic micro-organism isolated in the inflammatory si ... | 1999 | 10423739 |
| oral microflora in subjects with reduced salivary secretion. | it is generally assumed that a decreased salivary secretion rate will promote plaque accumulation and increase the risk for caries, gingival inflammation, and mucosal infections. in this study, the effect of hyposalivation on the oral microflora was examined. the following micro-organisms were analyzed in rinsing samples from 14 subjects with hyposalivation: the total number of anaerobically growing micro-organisms, alpha-hemolytic streptococci, mutans streptococci, lactobacilli, fusobacterium n ... | 1999 | 10439028 |
| antigen activation of thp-1 human monocytic cells after stimulation with lipopolysaccharide from oral microorganisms and granulocyte-macrophage colony-stimulating factor. | a human thp-1 monocyte cell line culture system has been utilized to evaluate the morphological changes in thp-1 cells and to measure expression of activation antigens (cd-11b, cd-11c, cd-14, cd-35, cd-68, cd-71 and hla-dr) as evidence of maturation of thp-1 cells in response to stimulation by lipopolysaccharide (lps) from the oral microorganisms, fusobacterium nucleatum and porphyromonas gingivalis, and granulocyte-macrophage colony-stimulating factor. thp-1 cells were stimulated with lps (1 mi ... | 1999 | 10444744 |
| infection-stimulated infraosseus inflammation and bone destruction is increased in p-/e-selectin knockout mice. | infections of the dental pulp commonly result in infraosseus inflammation and bone destruction. however, the role of phagocytic leucocytes in the pathogenesis of pulpal infections has been uncertain. in this work we used p/e-/- selectin-deficient mice, which lack rolling adhesion of leucocytes to endothelium and mimic the human syndrome, leucocyte adhesion deficiency ii (lad-ii), to test the hypothesis that phagocytic leucocytes protect against pulpal infection and subsequent periapical infraoss ... | 1999 | 10447722 |
| fusobacterium nucleatum septicemia and portal vein thrombosis. | 1999 | 10451179 | |
| the effects of hiv viral load on the phagocytic activity of monocytes activated with lipopolysaccharide from oral microorganisms. | a study was undertaken to determine whether viral load status in hiv+ patients has any potential effect on monocyte phagocytic function both before and after challenge of the monocytes with lipopolysaccharide (lps) isolated from oral microorganisms. lps of two putative periodontal pathogens porphyromonas gingivalis (p. gingivalis) and fusobacterium nucleatum (f. nucleatum) was prepared. whole blood samples in edta were collected from 30 hiv+ patients presenting for dental care at the university ... | 1999 | 10466072 |
| in vitro activity of gemifloxacin (sb 265805) against anaerobes. | gemifloxacin mesylate (sb 265805), a new fluoronaphthyridone, was tested against 359 recent clinical anaerobic isolates by the national committee for clinical laboratory standards reference agar dilution method with supplemented brucella blood agar and an inoculum of 10(5) cfu/spot. comparative antimicrobials tested included trovafloxacin, levofloxacin, grepafloxacin, sparfloxacin, sitafloxacin (du-6859a), penicillin g, amoxicillin clavulanate, imipenem, cefoxitin, clindamycin, and metronidazole ... | 1999 | 10471570 |
| microbiological response of localized sites with recurrent periodontitis in maintenance patients treated with tetracycline fibers. | whether adjunctive tetracycline fibers can provide an additive effect to scaling and root planing in treating non-responsive sites in maintenance subjects is still controversial. recolonization of the bacteria from untreated sites or from the extracrevicular region may explain the insignificant response to local therapy. the purpose of the present study was to evaluate the microbiological response of sites treated with tetracycline fibers combined with scaling and root planing. | 1999 | 10476893 |
| primary psoas abscess due to fusobacterium nucleatum. | a case of primary pyogenic psoas abscess due to fusobacterium nucleatum is described. clinicians must maintain a high index of clinical suspicion for the diagnosis of psoas abscess. although staphylococcus aureus accounts for most cases of primary psoas abscess, this report emphasizes the importance of bacteriological confirmation of the microorganism involved. | 1999 | 10482067 |
| microbiological features of papillon-lefèvre syndrome periodontitis. | papillon-lefevre syndrome patients exhibit hyperkeratosis palmo-plantaris and severe periodontitis. the syndrome is an autosomal recessive trait, but the mechanism of periodontal destruction is not known. this report presents the clinical and microbiological features of an 11-year old girl with papillon-lefèvre syndrome. clinical examination included conventional periodontal measurements and radiographic analysis. in samples from 3 deep periodontal lesions, the occurrence of major suspected peri ... | 1999 | 10487314 |
| 2-hydroxyglutaryl-coa dehydratase from clostridium symbiosum. | component d (hgdab) of 2-hydroxyglutaryl-coa dehydratase from clostridium symbiosum was purified to homogeneity. it is able to use component a from acidaminococcus fermentans (hgdc) to initiate catalysis together with atp, mg2+ and a strong reducing agent such as ti(iii)citrate. component d from c. symbiosum has a 6 x higher specific activity compared with that from a. fermentans and contains a second [4fe-4s] cluster but the same amount of riboflavin 5'-phosphate (1.0 per heterodimeric enzyme, ... | 1999 | 10491198 |
| establishment of oral anaerobes during the first year of life. | anaerobic species constitute a significant part of the bacterial community of the mouth. although the time and species involved in the primary colonization of infants are of great importance by forming the basis for further colonization, the development of the oral anaerobic microflora with age is still inadequately understood. in the present study, time and succession of colonization of oral anaerobes were longitudinally examined in 44 healthy caucasian infants at 2, 6, and 12 months of age. un ... | 1999 | 10520968 |
| utilization of d-amino acids by fusobacterium nucleatum and fusobacterium varium. | the utilization of d- and l-amino acids with acidic, basic or polar side chains was demonstrated by hplc. two species of the anaerobe fusobacterium utilized d-lysine and the l isomers of glutamate, glutamine, histidine, lysine and serine. only f. varium used l-arginine, d-glutamate and d-serine as substrates, whereas f. nucleatum specifically utilized d-histidine and d-glutamine. d-glutamate accumulated in f. nucleatum cultures supplemented with d-glutamine, and ornithine was detected when eithe ... | 1999 | 10524276 |
| an evaluation of the action of different root canal irrigants on facultative aerobic-anaerobic, obligate anaerobic, and microaerophilic bacteria. | the aim of this study was to test the effect of different concentrations of sodium hypochlorite, chlorhexidine, and cetrimide on the following bacterial strains: facultative aerobes-anaerobes: candida albicans atcc 10231; enterococcus faecalis atcc 29212; escherichia coli atcc 25,922; pseudomonas aeruginosa atcc 27,853; streptococcus mitis atcc 9811; streptococcus mutans atcc 35668; streptococcus salivarius atcc 13419; and streptococcus sanguis atcc 10556. microaerophiles: actinobacillus actinom ... | 1999 | 10530260 |
| dexamethasone differentially regulates cytokine transcription and translation in macrophages responding to bacteria or okadaic acid. | many microorganisms and microbial products induce expression of pro-inflammatory cytokines such as interleukin-1 (il-1alpha/beta) and tumour necrosis factor-alpha (tnf-alpha) in macrophages, primarily by transcriptional activation. we show here, by using mouse macrophages in primary culture, that pre-treatment with dexamethasone inhibits bacteria-induced il-1beta expression as mrna and cellular pro-il-1beta in parallel, consistent with an effect primarily on transcriptional activation. in contra ... | 1999 | 10530874 |
| arbitrarily primed-polymerase chain reaction for identification and epidemiologic subtyping of oral isolates of fusobacterium nucleatum. | fusobacterium nucleatum is the most frequently isolated bacterium in periodontal disease and plays an important role in serious infections in other parts of the body. arbitrarily primed-polymerase chain reaction (ap-pcr) was used to construct primers for specific identification and subtyping of f. nucleatum. subtypes may differ in virulence and, hence, are important as periodontal pathogens. subtypes also may differ in antibiotic susceptibility; therefore, knowing the subtypes may influence choi ... | 1999 | 10534075 |
| infective endocarditis due to fusobacterium nucleatum in an intravenous drug abuser. | infective endocarditis due to anaerobic non-spore-forming gram-negative bacilli in intravenous drug abusers is exceedingly rare, with only two cases being previously reported in the literature. a case of endocarditis due to fusobacterium nucleatum in an intravenous drug abuser is reported, accompanied by a review of the literature. | 1999 | 10534188 |
| enhanced interleukin-8 production in thp-1 human monocytic cells by lipopolysaccharide from oral microorganisms and granulocyte-macrophage colony-stimulating factor. | granulocyte-macrophage colony-stimulating factor (gm-csf) has been used to assist in bone marrow recovery during cancer chemotherapy. interleukin-8 (il-8) plays an important role in macrophage mediated inflammatory processes including exacerbation of periodontal diseases, one of the most common complications in gm-csf receiving cancer patients. the effect of gm-csf supplementation on il-8 production was investigated in a human monocyte cell line thp-1, stimulated with lipopolysaccharide extracte ... | 1999 | 10551153 |
| nosocomial sinusitis with isolation of anaerobic bacteria in icu patients. | to determine the frequency and the eventual clinical characteristics of nosocomial sinusitis with anaerobic bacteria isolation in patients in the intensive care unit (icu). | 1999 | 10551960 |
| acquisition of plasmin activity by fusobacterium nucleatum subsp. nucleatum and potential contribution to tissue destruction during periodontitis. | fusobacterium nucleatum subsp. nucleatum has been associated with a variety of oral and nonoral infections such as periodontitis, pericarditis, bone infections, and brain abscesses. several studies have shown the role of plasmin, a plasma serine protease, in increasing the invasive capacity of microorganisms. in this study, we investigated the binding of human plasminogen to f. nucleatum subsp. nucleatum, and its subsequent activation into plasmin. plasminogen-binding activity of bacterial cells ... | 1999 | 10569761 |
| fusobacterium nucleatum empyema necessitans. | 1999 | 10585835 | |
| longitudinal study of dental implants in a periodontally compromised population. | the purpose of this longitudinal study was to determine the clinical status and the composition of the subgingival microbiota of dental implants and natural teeth in patients with a history of periodontitis. | 1999 | 10588495 |
| pre- and post-implantation microbiota of the tongue, teeth, and newly placed implants. | this investigation sought intra-oral sources of species colonizing dental implants. | 1999 | 10599911 |
| oral microbial flora in sjögren's syndrome. | to study presence of microorganisms associated with caries, gingivitis, oral opportunistic infections, and extent of hyposalivation in dentate patients with primary and secondary sjögren's syndrome (ss). | 1999 | 9918250 |
| unexpected cross-reaction with fusobacterium necrophorum in a pcr for detection of mycoplasmas. | cross-reactions with fusobacterium necrophorum were found in a pcr designed for detection of a wide range of mycoplasma species. twenty-five strains of fusobacterium were examined; all 14 f. necrophorum strains reacted positively, whereas all 7 fusobacterium nucleatum strains reacted negatively. two strains that were not f. necrophorum yielded variable results. | 1999 | 9986867 |
| elastase activity of anaerobes isolated from amniotic fluid with preterm premature rupture of membranes. | a total of 131 anaerobes isolated from amniotic fluid with preterm premature rupture of membranes and stored were examined for elastolytic activity by the method described by williams et al (lett appl microbiol 1988;7:173-6). | 1999 | 9988804 |
| microbiota of successful osseointegrated dental implants. | the long-term survival of dental implants depends, in part, on control of bacterial infection in the peri-implant region. periodontal pathogens colonized implants symptomatic through infection, whereas the microbiota of successful implants was similar to that of periodontal health. this study examined the impact on the peri-implant microbiota of crown restorations; implant type; length of time of loading; history of implant or periodontal infections; and whether implants replaced single or multi ... | 1999 | 10102550 |
| identification of positively charged residues of foma porin of fusobacterium nucleatum which are important for pore function. | foma porin is the major outer-membrane protein of fusobacterium nucleatum. it exhibits the functional properties of a general diffusion porin, but has no sequence similarity to other porins. according to the proposed topology model, each monomer of this trimeric protein is a beta-barrel consisting of 16 transmembrane segments with eight surface-exposed loops. several conserved charged residues are proposed to extend from the beta-barrel wall into the aqueous channel lumen, and may contribute to ... | 1999 | 10103012 |
| haemagglutination and haemolysis by oral fusobacterium nucleatum. | haemagglutination and haemolytic activity of 80 fusobacterium nucleatum isolates from human and animal origin, on different human blood types was evaluated. all the isolates were able to agglutinate erythrocytes and the most were either alpha-haemolytic or beta-haemolytic. no specificity between haemolysin or haemagglutinin and blood type was observed. haemagglutination activity was inhibited when d-galactose, d-lactose or d-raffinose were used. haemagglutination and haemolysis may be important ... | 1999 | 10190119 |
| coaggregation of candida dubliniensis with fusobacterium nucleatum. | the binding of microorganisms to each other and oral surfaces contributes to the progression of microbial infections in the oral cavity. candida dubliniensis, a newly characterized species, has been identified in human immunodeficiency virus-seropositive patients and other immunocompromised individuals. c. dubliniensis phenotypically resembles candida albicans in many respects yet can be identified and differentiated as a unique candida species by phenotypic and genetic profiles. the purpose of ... | 1999 | 10203506 |
| induction of anti-thymocyte/t lymphocyte antibodies in mice injected with lipopolysaccharides from periodontopathic bacteria. | we examined the levels of anti-thymocyte/t lymphocyte autoantibody (ata) in the serum of mice injected intraperitoneally with lipopolysaccharides (lps) from periodontopathic bacteria; porphyromonas gingivalis, actinobacillus actinomycetemcomitans, fusobacterium nucleatum, capnocytophaga ochracea, and non-oral escherichia coli. all of the lps induced igm-ata. among these, lps from c. ochracea induced the highest level of igm-ata, whereas that of p. gingivalis induced the lowest. the peritoneal t ... | 1999 | 10207839 |
| beta-lactamase production and antimicrobial susceptibility of oral heterogeneous fusobacterium nucleatum populations in young children. | oral fusobacterium nucleatum populations from 20 young, healthy children were examined for beta-lactamase production. ten children (50%) harbored, altogether, 25 beta-lactamase-positive f. nucleatum isolates that were identified as f. nucleatum subsp. polymorphum, f. nucleatum subsp. nucleatum, and f. nucleatum subsp. vincentii (j. l. dzink, m. t. sheenan, and s. s. socransky, int. j. syst. bacteriol. 40:74-78, 1990). in vitro susceptibility of these beta-lactamase-producing and 26 non-beta-lact ... | 1999 | 10223950 |
| periodontal bacteria in adult twins. | both environmental and genetic factors are known to influence clinical measures of periodontal disease. the purpose of this study was to determine whether genetic factors similarly influence the presence of specific periodontal bacteria in subgingival plaque. | 1999 | 10225542 |
| microbiological and clinical effects of a 1% chlorhexidine-gel in untreated periodontal pockets from adult periodontitis patients. | the aim of this study was to report the microbiological and clinical effects of repeated subgingival administration of a 1% chlorhexidine-gel in periodontal pockets from 10 patients with adult periodontitis. results showed that the experimental treatment significantly improved clinical parameters (plaque index, gingival bleeding index, and pocket probing depth). direct subgingival administration of chlorhexidine-gel also produced a remarkable modification in the proportions of putative periodont ... | 1999 | 10322610 |
| [effect of lipopolysaccharide on recombinant human osteogenic protein-1-induced responses in human dental pulp cells]. | to investigate the effects of lipopolysaccharide (lps) on recombinant human osteogenic protein-1 (rhop-1) induced proliferation and differentiation. | 1999 | 12539700 |
| [anaerobic infection and its rapid detection in surgical patients]. | to investigate anaerobic infection and its rapid detection in surgical patients. | 1999 | 11829950 |
| evaluation of the rapid id 32a system for identification of anaerobic gram-negative bacilli, excluding the bacteroides fragilis group. | objective: to evaluate the rapid id 32a system (biomérieux, marcy-l'etoile, france) for the identification of anaerobic gram-negative bacilli, excluding the bacteroides fragilis group. methods: five hundred and twenty-eight identified clinical isolates of non-b. fragilis group anaerobic gram-negative bacilli were tested in the rapid id 32a system, and identifications were compared with those obtained with conventional biochemical tests and gas-liquid chromatography. results: the rapid id 32a sys ... | 1999 | 11856276 |
| antianaerobic activity of a cecropin---melittin peptide. | objective: several small, 15-residue peptides that contain portions of the amino acid sequences of both cecropin a and melittin have previously been shown to have broad-spectrum antibacterial activities against aerobic microorganisms, with no undesirable hemolytic properties. it would also be useful to know what effect these hybrid peptides have on anaerobic bacteria. methods: the minimum inhibitory concentrations of one hybrid, ca(1--7)m(2--9)nh2, were compared with those of seven other antimic ... | 1998 | 11864323 |
| c-telopeptide pyridinoline cross-links (ictp) and periodontal pathogens associated with endosseous oral implants. | detection of periodontal or peri-implant sites exhibiting progressing disease or those at risk of deterioration has proven difficult. pyridinoline cross-linked carboxyterminal telopeptide of type i collagen (ictp), a marker specific for bone degradation found in gingival crevicular fluid (gcf), has been associated with both bone and attachment loss in periodontitis and may be useful for predicting disease activity. the aim of this cross-sectional study was to examine the relationship between ict ... | 1998 | 11429938 |
| the microbial spectrum of brain abscess with special reference to anaerobic bacteria. | the bacteriological and clinical findings of 18 cases of brain abscess are presented. identification and antimicrobial susceptibility of anaerobic strains was performed both by conventional methods and the newer rapid ana ii panel and e-test methods, respectively. characterization of the anaerobic isolates was done by restriction fragment length polymorphism (rflp). anaerobic or aerobic organisms alone were recovered in three (16.6%), and mixed aerobic and anaerobic in another three (16.6%) pati ... | 1998 | 11013664 |
| inflammatory cytokine production and specific antibody responses against possible causative bacteria in patients with multilesional periapical periodontitis. | we examined the induction of inflammatory cytokines (including interleukin-1, interleukin-6, interleukin-8, and tumor necrosis factor-alpha) by several species of possible causative bacteria in periapical periodontitis. assays were done on human whole blood cultures from patients with differing numbers of periapical lesions; those having radiographically clear periapical lesions in 10 or more teeth (high lesion group), in one or two teeth (low lesion group), and healthy volunteers having no peri ... | 1998 | 10023261 |
| coronal leakage: endotoxin penetration from mixed bacterial communities through obturated, post-prepared root canals. | coronal leakage has been considered as one of the major causes of failure in root canal treatment. bacteria have been shown to penetrate the root canal obturating materials and influence the periapical tissues. endotoxin, a component of gram-negative bacteria, is a potent inflammatory agent and may be able to penetrate obturating materials faster than bacteria. this in vitro study examined the possible penetration of post-prepared canals by endotoxin and bacterial cells derived from mixed bacter ... | 1998 | 9922745 |
| characterization of a novel n-acetylneuraminic acid-specific fusobacterium nucleatum pk1594 adhesin. | fusobacterium nucleatum has been identified as significantly associated with sites with active periodontal disease and, as a group, the oral fusobacteria coaggregate with members of all oral bacteria genera tested. monoclonal antibodies were prepared and used in conjunction with other potential inhibitors, such as simple sugars and amino acids, to characterize coaggregation interactions, of f. nucleatum pk1594. four unique monoclonal antibodies, 5h11, 14c7, 19f2 and 29c12, were obtained by their ... | 1998 | 9573822 |
| helicobacter pylori adheres selectively to fusobacterium spp. | helicobacter pylori strains atcc 43504 and atcc 43629 were tested for their ability to coaggregate with 79 strains of bacteria representing 16 genera. all except two of the strains were of human origin, and most of the strains were isolated from the oral cavity. the helicobacters failed to coaggregate with all strains except the fusobacteria. several coaggregations were partially or completely inhibited by lactose. strong coaggregation was seen with each of four subspecies of fusobacterium nucle ... | 1998 | 9573823 |
| trovafloxacin compared with levofloxacin, ofloxacin, ciprofloxacin, azithromycin and clarithromycin against unusual aerobic and anaerobic human and animal bite-wound pathogens. | the activity of trovafloxacin and five other oral agents against 250 aerobic and 137 anaerobic strains isolated from human and animal bite wounds was determined by an agar dilution method. trovafloxacin was active against all aerobic and fastidious facultative isolates at < or = 0.5 mg/l and all anaerobes at < or = 2 mg/l (bacteroides tectum, porphyromonas salivosa and prevotella heparinolytica, < or = 0.25 mg/l; porphyromonas spp., < or = 0.5 mg/l; prevotella spp. and peptostreptococci, < or = ... | 1998 | 9578167 |
| activities of hmr 3004 (ru 64004) and hmr 3647 (ru 66647) compared to those of erythromycin, azithromycin, clarithromycin, roxithromycin, and eight other antimicrobial agents against unusual aerobic and anaerobic human and animal bite pathogens isolated from skin and soft tissue infections in humans. | the activities of hmr 3004 and hmr 3647 and comparator agents, especially macrolides, were determined by the agar dilution method against 262 aerobic and 120 anaerobic strains isolated from skin and soft tissue infections associated with human and animal bite wounds. hmr 3004 and hmr 3647 were active against almost all aerobic and fastidious facultative isolates (mic at which 90% of the isolates are inhibited [mic90], < or = 0.5 and 1 microg/ml, respectively) and against all anaerobes [bacteroid ... | 1998 | 9593139 |
| volatile fatty acid, metabolic by-product of periodontopathic bacteria, induces apoptosis in wehi 231 and raji b lymphoma cells and splenic b cells. | the ability of butyric acid, an extracellular metabolite from periodontopathic bacteria, to induce apoptosis in murine wehi 231 cells, splenic b cells, and human raji cells was examined. the culture filtrate of porphyromonas gingivalis, prevotella loescheii, and fusobacterium nucleatum, which contains high a percentage of butyric acid, induced dna fragmentation in wehi 231 cells. volatile fatty acid, especially butyric acid, significantly suppressed b-cell viability in a concentration-dependent ... | 1998 | 9596720 |
| granulocyte-macrophage colony-stimulating factor amplification of interleukin-1beta and tumor necrosis factor alpha production in thp-1 human monocytic cells stimulated with lipopolysaccharide of oral microorganisms. | cytokines, including granulocyte-macrophage colony-stimulating factor (gm-csf), are used to assist in bone marrow recovery during cancer chemotherapy. interleukin-1beta (il-1beta) and tumor necrosis factor alpha (tnf-alpha) play important roles in inflammatory processes, including exacerbation of periodontal diseases, one of the most common complications in patients who undergo this therapy. a human monocyte cell line (thp-1) was utilized to investigate il-1beta and tnf-alpha production followin ... | 1998 | 9605989 |
| studies on fusobacteria associated with periodontal diseases. | the physiological and metabolic characteristics of representative isolates of the various subspecies of fusobacterium nucleatum were investigated by growing them in continuous culture in chemically-defined, media. behaving almost identically, these organisms were found to obtain energy from the fermentation of simple carbohydrates such as glucose or fructose or from the fermentation of certain amino acids, free or in the form of small peptides. the latter can be attacked by aminopeptidase activi ... | 1998 | 9612984 |
| development of an anaerobic bacterial leakage model. | the majority of bacteria associated with infections of endodontic origin are strict anaerobes. the purpose of this study was to develop an endodontic microleakage model using strict anaerobic bacteria in a two-chamber system. nine species of anaerobic bacteria were tested for viability and detection by either turbidity or color change of the broth. a survey of ph chromogenic substrates revealed that bromcresol purple (ph 5.2 = yellow, ph 6.8 = purple) could be used as a chromogenic indicator to ... | 1998 | 9641124 |
| the effect of herbal extracts in an experimental mouthrinse on established plaque and gingivitis. | the purpose of the present study was to establish in vitro the inhibiting effect of a herbal extract mixture on a selected number of micro-organisms and to test in vivo the effect of a mouthwash containing 6.3 mg/ml herbal extract mixture on plaque and gingivitis as compared to a minus active control mouthrinse. the herbal extract was a mixture of: juniperus communis (juniper), urtica dioca (nettle), achillaea millefolium (yarrow); 1:1:1. in the study, in-vitro, the effect of pure herbal extract ... | 1998 | 9650877 |
| subgingival microflora associated with nifedipine-induced gingival overgrowth. | the purpose of this study was to examine the composition of subgingival plaque of 140 periodontal lesions in 35 patients with cardiovascular disorders who were administered nifedipine and manifested nifedipine-induced gingival overgrowth (go). age was inversely associated with the go. plaque index and bleeding index showed a significant association with go, while nifedipine dosage and duration of nifedipine therapy were not found to be significant predictors of go. the gingival inflammation as e ... | 1998 | 9660335 |
| severity of localized juvenile periodontitis as related to polymorphonuclear chemotaxis and specific microbial isolates. | the purpose of this study was twofold: (a) to determine if an association exists between severity of localized juvenile periodontitis (ljp) and impairment of polymorphonuclear leukocyte (pmn) chemotaxis and/or colonization by specific microbial isolates; (b) to determine if the number of specific microbial isolates, i.e., actinobacillus actinomycetemcomitans, porphyromonas gingivalis, prevotella intermedia, fusobacterium nucleatum, eikenella corrodens, and campylobacter rectus correlates to clin ... | 1998 | 9663117 |
| cytotoxic effect of endodontic bacteria on periapical fibroblasts. | this study was conducted to investigate the effects of sonicated bacterial extracts (sbes) from anaerobic gram-negative bacteria on periapical fibroblast obtained from the apical portion of human periodontal ligaments. porphyromonas endodontalis, porphyromonas gingivalis, prevotella intermedia, and fusobacterium nucleatum were chosen from among the endodontic bacteria isolated from root canals having a periapical lesion and compared in terms of their cytotoxicity. the purpose of this study was t ... | 1998 | 9759015 |
| sinusitis in neurologically impaired children. | the microbiologic features of infected sinus aspirates in nine children with neurologic impairment were studied. anaerobic bacteria, always mixed with aerobic and facultative bacteria, were isolated in 6 (67%) aspirates and aerobic bacteria only in 3 (33%). there were 24 bacterial isolates, 12 aerobic or facultative and 12 anaerobic. the predominant aerobic isolates were klebsiella pneumoniae, escherichia coli, and staphylococcus aureus (2 each) and proteus mirabilis, pseudomonas aeruginosa, hae ... | 1998 | 9781990 |
| microbiological findings in prepubertal periodontitis. a case report. | generalized pre-pubertal periodontitis (gpp) is a rare entity that usually affects children with severe systemic diseases. we report the case of a 7-year-old male patient diagnosed with gpp, with no apparent systemic condition, who lost all his primary teeth to periodontal disease. before extractions, while he was still in mixed dentition the subgingival plaque was collected and analyzed using dna probes to 40 different microorganisms. putative periodontopathogens such as prevotella intermedia, ... | 1998 | 9802719 |
| functional changes in thp-1 human monocytic cells after stimulation with lipopolysaccharide of oral microorganisms and granulocyte macrophage colony stimulating factor. | a human thp-1 monocyte cell line culture system has been utilized to observe the effect of granulocyte macrophage colony stimulating factor (gm-csf) supplementation with lipopolysaccharide (lps) of oral microorganisms to stimulate monocyte/macrophage functional activity. lps of oral microorganisms, fusobacterium nucleatum and porphyromonas gingivalis was produced by phenol-water extraction and characterized. the phagocytosis assay was performed using f1tc labeled saccharomyces yeast particles. p ... | 1998 | 9805230 |
| bacterial eradication from root dentine by ultrasonic irrigation with sodium hypochlorite. | the study aimed to evaluate intracanal irrigation procedures in eradicating bacteria from surface, shallow and deep layers of root dentine using extracted human teeth. artificial bacterial smear layer was successfully produced by rubbing a mixture of dental plaque and artificially decalcified dentine or carious dentine on root canal walls. the reservoir holes were 3.5 mm in depth, 1 mm in diameter prepared 1.5 mm apart and parallel to the root canals on the decrowned planes, in which five separa ... | 1998 | 9823113 |
| polymicrobial coronal leakage of super eba root-end fillings following two methods of root-end preparation. | the aim of this study was to compose in vitro coronal leakage of a super eba root-end filling material after two root-end cavity preparation techniques. a mixed anaerobic microbial marker was used. forty-five extracted human teeth with straight, single root canals were prepared chemo-mechanically to a size 40 master apical file. the teeth were divided into experimental groups (35 teeth) and control groups (10 teeth). forty teeth (35 experimental teeth and five negative control teeth) were obtura ... | 1998 | 9823138 |