| antibacterial effects of chemomechanical instrumentation and calcium hydroxide in primary teeth with pulp necrosis. | this study's purposes were to: evaluate the antibacterial effect of chemomechanical instrumentation and a calcium hydroxide-based dressing in primary teeth with pulp necrosis secondary to trauma; and detect the presence of fusobacterium nucleatum and black-pigmented rods in the canals of these teeth. | 2011 | 21902996 |
| The role of aggregation in Fusobacterium nucleatum- induced immune cell death. | Fusobacterium nucleatum, an anaerobic oral bacterium, has been shown to be highly abundant in endodontic infections. Its role in these infections remains unclear. Previous studies have shown that F. nucleatum could aggregate immune cells. We have demonstrated that F. nucleatum can induce significant apoptosis in peripheral blood mononuclear cells (PBMCs). In this in vitro study, we sought to determine what role this aggregation phenomenon has on the induction of apoptosis in PBMCs. | 2011 | 22000457 |
| Levels of periodontal pathogens in neonatal gastric aspirates and possible maternal sites of origin. | Maternal periodontal infection has been recognized as a risk factor for preterm and low birthweight infants. It is suspected that pathogens causing periodontal disease may translocate to the amniotic cavity and so contribute to triggering an adverse pregnancy outcome. This study aimed to determine levels and proportions of periodontal bacteria in neonatal gastric aspirates obtained from complicated pregnancies and the respective maternal oral and vaginal samples using a quantitative polymerase c ... | 2011 | 21896155 |
| Nonvolatile S-alk(en)ylthio-L-cysteine derivatives in fresh onion (Allium cepa L. cultivar). | The L-cysteine derivatives (R)-2-amino-3-(methyldisulfanyl)propanoic acid (S-methylthio-L-cysteine), (R)-2-amino-3-(propyldisulfanyl)propanoic acid (S-propylthio-L-cysteine), (R)-2-amino-3-(1-propenyldisulfanyl)propanoic acid (S-(1-propenylthio)-L-cysteine), and (R)-2-amino-3-(2-propenyldisulfanyl)propanoic acid (S-allylthio-L-cysteine) were prepared from 3-[(methoxycarbonyl)dithio]-L-alanine, obtained from the reaction of L-cysteine with methoxycarbonylsulfenyl chloride. The occurrence of these ... | 2011 | 21854077 |
| Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma. | An estimated 15% or more of the cancer burden worldwide is attributable to known infectious agents. We screened colorectal carcinoma and matched normal tissue specimens using RNA-seq followed by host sequence subtraction and found marked over-representation of Fusobacterium nucleatum sequences in tumors relative to control specimens. F. nucleatum is an invasive anaerobe that has been linked previously to periodontitis and appendicitis, but not to cancer. Fusobacteria are rare constituents of the ... | 2011 | 22009989 |
| fusobacterium nucleatum prosthetic hip infection in an adult with sickle cell-beta thalassemia. | fusobacterium nucleatum is an anaerobic gram-negative bacillus commensal to the human oropharynx and gastrointestinal tract which causes an array of human infection, yet it has never been associated with infection of prosthetic joints. we report the first case of prosthetic hip infection caused by f. nucleatum in a man with sickle cell-beta thalassemia. | 2011 | 22002730 |
| isolation and molecular identification of fusobacterium nucleatum from nigerian patients with oro-facial infections. | fusobacterium nucleatum is one of the most common anaerobic bacteria present in the oral cavity and is often isolated from infections involving other body sites. | 2011 | 21984462 |
| synergy in biofilm formation between fusobacterium nucleatum and prevotella species. | the formation of biofilm by anaerobic, gram-negative bacteria in the subgingival crevice plays an important role in the development of chronic periodontitis. the aim of this study was to characterize the role of coaggregation between fusobacterium nucleatum and prevotella species in biofilm formation. coaggregation between f. nucleatum and prevotella species was determined by visual assay. effect of co-culture of the species on biofilm formation was assessed by crystal violet staining. effect of ... | 2011 | 21945879 |
| analysis of symptomatic and asymptomatic primary root canal infections in adult norwegian patients. | this molecular study analyzed the microbiota of primary root canal infections from adult norwegian patients. | 2011 | 21846535 |
| extracellular deoxyribonuclease production by periodontal bacteria. | palmer lj, chapple ilc, wright hj, roberts a, cooper pr. extracellular deoxyribonuclease production by periodontal bacteria. j periodont res 2011; doi: 10.1111/j.1600-0765.2011.01451.x © 2011 john wiley & sons a/s background and objective: whilst certain bacteria have long been known to secrete extracellular deoxyribonuclease (dnase), the purpose in microbial physiology was unclear. recently, however, this enzyme has been demonstrated to confer enhanced virulence, enabling bacteria to evade the ... | 2011 | 22150619 |
| in vitro antibacterial activity of galls of quercus infectoria olivier against oral pathogens. | the galls of quercus infectoria are commonly used in malay traditional medicine to treat wound infections after childbirth. in india, they are employed traditionally as dental applications such as that in treatment of toothache and gingivitis. the aim of the present study was to evaluate the antibacterial activity of galls of quercus infectoria olivier against oral bacteria which are known to cause dental caries and periodontitis. methanol and acetone extracts were screened against two gram-posi ... | 2012 | 22203875 |
| antimicrobial effects of o-cymen-5-ol and zinc, alone & in combination in simple solutions and toothpaste formulations. | this study aimed to evaluate antimicrobial effects of an o-cymen-5-ol/zinc system. | 2011 | 21762153 |
| Signal peptide of FadA adhesin from Fusobacterium nucleatum plays a novel structural role by modulating the filament's length and width. | FadA, a novel adhesin of periodontal pathogen Fusobacterium nucleatum is composed of two forms, pre-FadA and mature FadA (mFadA), constituting the functional FadA complex (FadAc). By electron microscopy, we observed that mFadA formed uniformly long and thin filaments, while FadAc formed heterogeneous filaments of varying lengths and widths, as well as "knots". Mutants in signal peptide or in the non-alpha-helical loop retaining heterogeneous structures had binding activity while those forming ag ... | 2012 | 22108653 |
| effect of a self-etching adhesive containing an antibacterial monomer on clinical periodontal parameters and subgingival microbiologic composition in orthodontic patients. | the aims of this study were to evaluate the effect of a self-etching adhesive system containing an antibacterial monomer on periodontal health and subgingival microbiologic composition in orthodontic patients and to compare it with a conventional adhesive system. | 2011 | 21967952 |
| evaluation of the subgingival microbiota of alcoholic and non-alcoholic individuals. | the aim of this study was to evaluate the composition of the subgingival microbiota of alcoholic and non-alcoholic individuals. | 2011 | 21864643 |
| a role of oral bacteria in bisphosphonate-induced osteonecrosis of the jaw. | no consensus has yet been reached to associate oral bacteria conclusively with the etio-pathogenesis of bisphosphonate-induced osteonecrosis of the jaw (bonj). therefore, the present study examined the effects of oral bacteria on the development of bonj-like lesions in a mouse model. in the pamidronate (pam)-treated mice, but not control non-drug-treated mice, tooth extraction followed by oral infection with fusobacterium nucleatum caused bonj-like lesions and delayed epithelial healing, both of ... | 2011 | 21921248 |
| [septic arthritis due to fusobacterium nucleatum in an immunocompetent patient.] | | 2011 | 22089068 |
| A case of craniocervical abscess with sinus thrombosis in Lemierre?s syndrome. | Abstract A 74-year old gentleman with a cranio-cervical abscess failed to improve after incision and drainage and standard intravenous antibiotic therapy. Imaging demonstrated thrombosis of the internal jugular vein, sigmoid sinus and transverse sinus; and microbiological analysis isolated Fusobacterium nucleatum. The diagnosis of Lemierre's syndrome was confirmed, and he was effectively treated with appropriate antibiotics and anti-coagulation. | 2011 | 22077587 |
| antibacterial activity of povidone-iodine against an artificial biofilm of porphyromonas gingivalis and fusobacterium nucleatum. | objective: to investigate the antibacterial activity of povidone-iodine (pvp-i) on an artificial dual species biofilm of periodontal pathogens. design: porphyromonas gingivalis or fusobacterium nucleatum grown in broth culture was inoculated on polycarbonate membrane (pcm) tissue culture inserts. after incubation for 72h, pvp-i solutions were applied to the biofilm for the time period ranging from 0.5 to 5min. after addition of a deactivator, each pcm was removed and the biofilm on the pcm was s ... | 2011 | 21958970 |
| Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential. | Isoliquiritigenin (1) and liquiritigenin (2) are structurally related flavonoids found in a variety of plants. The purpose of this study was to perform a comparative analysis of biological properties of these compounds in regard to their therapeutic potential for oral infections. Compound 1 demonstrated significant antibacterial activity against three major periodontopathogens, Porphyromonas gingivalis, Fusobacterium nucleatum, and Prevotella intermedia. In contrast, 2 exerted less pronounced ef ... | 2011 | 21866899 |
| The adhesion of oral bacteria to modified titanium surfaces: role of plasma proteins and electrostatic forces. | OBJECTIVES: Modifications of titanium (Ti) implant surfaces have a significant effect on early biofilm formation and the outcome of implant procedures. The aim of this study was to examine the role of plasma proteins and electrostatic forces in the adhesion mechanism of oral bacteria to modified Ti surfaces. MATERIALS AND METHODS: Ti discs with three different types of surface modifications, machined, acid-etched, and acid-etched and blasted, were examined for adhesion of oral bacteria: Streptoc ... | 2011 | 22150723 |
| investigation of six selected bacterial species in endo-periodontal lesions. | didilescu ac, rusu d, anghel a, nica l, iliescu a, greabu m, bancescu g, stratul si. investigation of six selected bacterial species in endo-periodontal lesions. international endodontic journal, 45, 282-293, 2012. abstract: aim to investigate and determine possible associations of six tested bacteria belonging to 'orange' and 'green' complexes, in endo-periodontal lesions: parvimonas micra, fusobacterium nucleatum, campylobacter rectus, eubacterium nodatum, eikenella corrodens and capnocytopha ... | 2011 | 22077868 |
| salivary β-galactosidase activity affects physiological oral malodour. | previous reports have associated salivary β-galactosidase activity with non-periodontopathic oral malodour. in this study, we investigated the localization of β-galactosidase and elucidated the relationship between its enzymatic activity and physiological oral malodour. | 2012 | 21885033 |
| Detection of odoriferous subgingival and tongue microbiota in diabetic and nondiabetic patients with oral malodor using polymerase chain reaction. | Halitosis has been correlated with the concentration of volatile sulfur compounds (VSCs) produced in the oral cavity by metabolic activity of bacteria colonizing the periodontal pockets and the dorsum of the tongue. It has been assumed that there is a relationship between periodontal disease and diabetes mellitus. | 2011 | 21891897 |
| The comparative evaluation of xanthan gel with chlorhexidine (Chlosite) in smokers and non-smokers: A clinical and microbiological assessment. | Prevention of the periodontal disease progression is the primary goal of periodontal therapy. When conventional therapy is found inadequate to attain periodontal health in chronic periodontitis, local antimicrobial agents have been used as an adjunct with scaling and root planning (SRP) which has reproduced encouraging results. Hence, this study was undertaken to evaluate the new sustained released local drug Chlosite clinically and microbiologically in smokers and non-smokers. | 2011 | 22028508 |
| colonisation of the oral cavity by periodontopathic bacteria in complete denture wearers. | gerodontology 2011; doi: 10.1111/j.1741-2358.2011.00506.x colonisation of the oral cavity by periodontopathic bacteria in complete denture wearers objective: the purpose of this study was to investigate colonisation by periodontopathic bacteria and the sites of colonisation in elderly upper and lower complete denture wearers. we also investigated the relationship between level of oral hygiene and colonisation by periodontopathic bacteria. materials and methods: forty edentulous and 37 dentate ... | 2011 | 21929616 |
| fusobacterium nucleatum and human beta-defensins modulate the release of antimicrobial chemokine ccl20/macrophage inflammatory protein 3α. | cells of the innate immune system regulate immune responses through the production of antimicrobial peptides, chemokines, and cytokines, including human beta-defensins (hbds) and ccl20. in this study, we examined the kinetics of primary human oral epithelial cell (hoec) production of ccl20 and hbds in response to fusobacterium nucleatum, a commensal bacterium of the oral cavity, which we previously showed promotes hoec induction of hbds. hoecs secrete maximal levels of ccl20 at 6 h, following st ... | 2011 | 21911466 |
| colorectal cancer: fusobacterium nucleatum found in colon cancer tissue--could an infection cause colorectal cancer? | | 2011 | 22083120 |
| limited in-depth invasion of fusobacterium nucleatum into in vitro reconstructed human gingiva. | objective: fusobacterium nucleatum is an opportunistic pathogen with a key role in subgingival plaque formation and it is found in increased numbers in periodontally affected sites. this study aimed to investigate the potential of f. nucleatum to penetrate and induce alterations in an in vitro reconstructed human gingival mucosa model. methods: three-dimensional (3d) organotypic models of human gingiva were engineered using primary gingival keratinocytes and fibroblasts. the reconstructed tissue ... | 2011 | 22024403 |
| Oral Bacterial DNA Differ in Their Ability to Induce Inflammatory Responses in Human Monocytic Cell Lines. | BACKGROUND: DNA of periodontal pathogens, Porphyromonas gingivalis (Pg-DNA) and Tannerella forsythia, stimulate cytokine production in human monocytic cells (THP-1) through Toll like receptor 9 (TLR-9) and nuclear factor kappa B signaling. Fusobacterium nucleatum is one of the most frequently isolated bacteria in periodontally-diseased tissues and reported to synergize with Porhyromonas gingivalis enhancing the pathogenicity. We investigated inflammatory mediator production in THP-1 cells challe ... | 2011 | 22166166 |
| microbial profile of patients with periodontitis compared with healthy subjects. | objective: to define and compare the microbiologic profile of subgingival plaque in german patients with periodontitis (including aggressive and advanced chronic periodontitis) and healthy subjects and to determine significant association between isolates and clinical status. aggregatibacter actinomycetemcomitans, porphyromonas gingivalis, and tannerella forsythia are major periodontal pathogens, though it is recognized that other species may also contribute to the pathogenesis of periodontal di ... | 2012 | 22257880 |
| fusobacterium nucleatum biofilm induces epithelial migration in an organotypic model of dento-gingival junction. | background: effects of fusobacterium nucleatum biofilm on epithelial cell proliferation, apoptotic cell death and basement membrane constituent collagen iv production were examined in an organotypic dento-epithelial (od-e) model. methods: the od-e model was constructed by seeding keratinocytes on fibroblast-containing collagen gels and by placing tooth pieces on the top. a 3-day-old biofilm of either a laboratory strain (atcc 25586) or a clinical strain (ahn 9508) of f. nucleatum was placed on ... | 2012 | 22248219 |
| necrotizing periodontal diseases in hiv-infected brazilian patients: a clinical and microbiologic descriptive study. | objective: nowadays, necrotizing periodontal diseases have a low prevalence; however, a better understanding of the etiopathogenesis of these diseases is necessary for determining more adequate preventive and therapeutic strategies. method and materials: from a pool of 1,232 hiv-infected patients, 15 presented with necrotizing periodontal diseases, which were evaluated by full-mouth periodontal clinical measurements. subgingival biofilm samples were collected from necrotizing lesions of six of t ... | 2012 | 22259811 |
| synergistic effect on biofilm formation between fusobacterium nucleatum and capnocytophaga ochracea. | the formation of dental plaque biofilm by specific gram-negative rods and spirochetes plays an important role in the development of periodontal disease. the aim of this study was to characterize biofilm formation by fusobacterium nucleatum and capnocytophaga ochracea. coaggregation between f. nucleatum and capnocytophaga species was determined by visual assay. biofilm formation was assessed by crystal violet staining. enhancement of biofilm formation by f. nucleatum via soluble factor of c. ochr ... | 2012 | 22252100 |
| oral microbial biofilm stimulation of epithelial cell responses. | oral bacterial biofilms trigger chronic inflammatory responses in the host that can result in the tissue destructive events of periodontitis. however, the characteristics of the capacity of specific host cell types to respond to these biofilms remain ill-defined. this report describes the use of a novel model of bacterial biofilms to stimulate oral epithelial cells and profile select cytokines and chemokines that contribute to the local inflammatory environment in the periodontium. monoinfection ... | 2012 | 22266273 |
| fusobacterium nucleatum groel induces risk factors of atherosclerosis in human microvascular endothelial cells and apoe(-/-) mice. | infection and inflammation are risk factors in the initiation and progression of atherosclerosis. periodontitis is one of the most prevalent chronic inflammations of the oral cavity, and has been reported to be associated with systemic disease. in this study, we evaluated whether the heat-shock protein groel of fusobacterium nucleatum, one of the most prevalent bacteria in periodontitis, induces factors that predispose to atherosclerosis in human microvascular endothelial cells (hmec-1) and apol ... | 2011 | 22394469 |
| internal decompressive craniectomy with craniotomy: a novel surgical therapy of giant frontal mucocele complicated by subdural empyema. | giant frontal mucocele (gfm) is an extremely rare cause of frontal lobe syndrome. subdural empyema (sde) is an uncommon complication of paranasal sinisutis, for which craniotomy and decompressive craniotomy are the most effective surgical procedures. | 2011 | 22368985 |
| evaluation of periodontal pathogens in amniotic fluid and the role of periodontal disease in pre-term birth and low birth weight. | pre-term birth and/or low birth weight (ptlbw) is a serious problem in developing countries. the absence of known risk factors in ≈ 50% of ptlbw cases has resulted in a continued search for other causes. the aim of this study was to examine the effect of periodontitis on pregnancy outcomes. | 2012 | 23638858 |
| antibacterial activity of essential oils against periodontal pathogens: a qualitative systematic review. | periodontal diseases are among the most common infectious diseases that lead to the destruction of periodontal tissues. anaerobic gram-negative bacteria (aggregatibacter actinomecetemcomitans, porphyromonas gingivalis, fusobacterium nucleatum...) isolated from periodontal lesions, have been shown to be related to the onset and progression of periodontal disease. given the incidence of periodontitis, increased resistance of oral bacteria to antibiotics and adverse effects of some antibacterial ag ... | 2012 | 23513511 |
| microbiology of the gut of the kola nut weevil, balanogastris kolae. | reports have shown that many insects have microbes in their gut system. gut microbes are very important for insect vitality and much of their nutrition is derived from products of microbial metabolism. the habitat of balanogastris kolae (desbrocher des loges) (coleoptera: curculionidae) suggests that they possess the ability to digest varieties of sugars particularly starch and protein materials present in the kola nut, cola nitida schott & endlicher (malvales: malvaceae). the aim of this study ... | 2012 | 23421598 |
| [expression of cytokines in dentogingival sulcus in patients after dental implantation and during development of peri-implantitis]. | determination of cytokine content in various areas of dentition in patients with peri-implantitis associated with parodontopathogenic bacteria species of i and ii order. | 2012 | 23297645 |
| variations in the oral anaerobic microbial flora in relation to pregnancy. | pregnancy gingivitis is a major oral infection. periodontium acts as a reservoir of inflammatory mediators and sub gingival biofilms of bacteria. | 2012 | 23285437 |
| validation of a quantitative real-time pcr assay and comparison with fluorescence microscopy and selective agar plate counting for species-specific quantification of an in vitro subgingival biofilm model. | subgingival biofilms are the prime etiological factor of periodontal disease. owing to their complex polymicrobial nature, quantification of individual bacterial species within the biofilm for research and diagnostic purposes can be methodologically challenging. the aims of this study were to establish a quantitative real-time pcr (qpcr) assay to quantify the bacteria used in our 10-species in vitro 'subgingival' biofilm model and to compare the quantitative outcome with fluorescence microscopy ... | 2012 | 23278531 |
| cerebral perfusion pressure: a hemodynamic mechanism of mannitol and the postmannitol hemogram. | sixteen patients each received infusions of 1 g of mannitol per kg over 5 to 10 minutes, and serial determinations of intracranial pressure (icp), systemic arterial blood pressure (sabp), central venous pressure, cerebral perfusion pressure (cpp), hematocrit, hemoglobin, serum na+, k+, osmolarity, and fluid balance were carried out for 4 hours. urine output was replaced volume for volume with 5% dextrose in 0.45% nacl solution. we tested the hypothesis that patients with high (greater than or eq ... | 2010 | 3116451 |
| [primary transport of acute patients. optimal use of rescue resources exemplified by the canton of graubünden]. | | 2011 | 3927607 |
| [subcutaneous rupture of tendons and muscles of the extremities]. | under study there were 278 patients with 285 subcutaneous ruptures of tendons and muscles of the upper and lower extremities. the tendon of the long head of the humeral biceps muscle and achilles tendon are most liable to subcutaneous ruptures (123 patients--43.2% and 97 patients--34% respectively). pathohistological examinations have shown that subcutaneous ruptures of tendons and muscles usually take place against the background of dystrophic alterations reducing their mechanical strength. the ... | 2012 | 3303625 |
| note on the oscillations of collapsible tubes. | | 2003 | 309045 |
| marijuana: pro and con. | | 2003 | 403763 |
| [experiences with incus autografts and preserved incus homografts in ear surgery (author's transl)]. | the healing process of free-transplantated incus autografts and preserved homografts in the middle-ear is largely non-irritating. they are suited for sound transmission. under the osteoinductive influence of the non-vital graft, ingrowing vascular connective tissue of the host differentiates itself in osteoblasts, osteoclasts and chondroblasts. the grafts are revitalised in relation to time. rarely a marked resorption of preserved incus homografts was noticed in consequence of an antigen-antibod ... | 2003 | 142874 |
| molecular orbital studies on lipids: conformation of glycerol trivalerate by the pcilo method. | | 2004 | 535925 |
| inducibility of metallothionein biosynthesis in cultured normal and menkes kinky hair disease fibroblasts: effects of copper and cadmium. | metallothionein biosynthesis is not induced by extracellular copper in menkes kinky hair disease (mkhd) or in normal cultured fibroblasts under the conditions of these experiments. in the presence of copper, mkhd fibroblasts also incorporated less cysteine than did normal fibroblasts. extracellular cadmium greatly enhanced the uptake of cysteine in both normal and mkhd cultures. by the technique of polyacrylamide gel electrophoresis, it was demonstrated that metallothionein is induced by cadmium ... | 2004 | 471576 |
| [low-molecular weight nuclear rna's]. | | 2004 | 395786 |
| practical use of electron microscopy for the diagnosis of glomerular disease. | in the past few years many clinically significant new glomerular lesions have been reported from observations made on renal biopsy specimens by electron microscopy. the clinical applicability of electron microscopy is illustrated by examples of specific ultrastructural patterns of glomerular reaction making possible a more accurate diagnosis, prognosis, and prediction of the response to treatment. | 2005 | 1150220 |
| pattern and depth discrimination from random dot stereograms. | the discrimination of depth and pattern was investigated using random dot stereograms. for all four subjects, the psychometric function for depth judgments (probability of correct response) was clearly superior to pattern judgments over a range of ten crossed or uncrossed binocular disparity values. degrading the visual images, either monocularly or binocularly, with various convex lens power (fogging lenses) reduced both depth and pattern discrimination across all disparity values, rather than ... | 2005 | 1130488 |
| morphometric analysis of the loss of chief and parietal cells after partial gastrectomy for duodenal ulcer. | relative chief and parietal cell volume densities were estimated morphometrically in the remnant mucosa of 98 male patients ("series"), operated on for duodenal ulcer by the billroth ii, and in the body mucosa of 55 subjects, age and sex matched, from a random series of a finnish population ("controls"). the relative volumes of chief and parietal cells were significantly lower in the series than in the controls. the mean chief cell: parietal cell ratio was significantly higher in the series than ... | 2005 | 549432 |
| acute myocardial infarction after blunt chest trauma in young people: need for prompt intervention. | we describe four cases of acute myocardial infarction in young patients, secondary to blunt chest trauma. one case was treated with intracoronary thrombolysis and angioplasty, two cases received systemic thrombolysis, and the last one did not have any reperfusion therapy. the coronary angiograms of the left anterior descending artery showed thrombosis in two cases, coronary dissection in one case, and no morphological lesions in the other. we encourage the early performance of angiographic studi ... | 2006 | 1764738 |
| [a case of idiopathic aseptic osteonecrosis of the patellae: repeat study of tc-99m hmdp bone scintigraphy in a reparative phase]. | a 37-year-old woman entered our hospital because of bilateral knee pain. tc-99m hmdp bone scintigram demonstrated increased activity in the bilateral patellae and cold lesion in the center and left lateral segments of the left patellae, so-called doughnut pattern. trephine biopsy was performed to prove bilateral idiopathic asepct osteonecrosis of the patellae. the knee pain subsided and a bone scan 5 months later demonstrated increased activity in the bilateral patellae more widely than initial ... | 2006 | 1800777 |
| [a case of idiopathic aseptic osteonecrosis of the patellae: repeat study of tc-99m hmdp bone scintigraphy in a reparative phase]. | a 37-year-old woman entered our hospital because of bilateral knee pain. tc-99m hmdp bone scintigram demonstrated increased activity in the bilateral patellae and cold lesion in the center and left lateral segments of the left patellae, so-called doughnut pattern. trephine biopsy was performed to prove bilateral idiopathic asepct osteonecrosis of the patellae. the knee pain subsided and a bone scan 5 months later demonstrated increased activity in the bilateral patellae more widely than initial ... | 2006 | 1800777 |
| carbohydrate specificity of the receptor sites of mistletoe toxic lectin-i. | the carbohydrate specificity of mistletoe toxic lectin-i (ml-i) was studied by haemagglutination-inhibition assay. the results indicated that ml-i has a broad range of affinity for gal alpha,beta linked sequences. the galabiose (e, gal alpha 1----4gal) sequence, a receptor of the uropathogenic e. coli ligand, was one of the best disaccharide inhibitors tested. the lectin also exhibits affinity for lac(gal beta 1----4glc), t(gal beta 1----3galnac), i/ii(gal beta 1----3/4glcnac) and b(gal alpha 1- ... | 2006 | 1525184 |
| "raynaud's disease" in migraineurs: one entity or two? | two cases are reported of patients who were diagnosed as having both migraine and raynaud's disease. because they were able to achieve effective control of both headaches and extremity temperature after undergoing a comprehensive approach--utilizing medication, biofeedback, and psychotherapy--it is suggested that both conditions are manifestations of the same disorder. it is recommended that a first step in approaching concurrent diagnoses of this type involve combined treatment as is often used ... | 2006 | 1446993 |
| milk--a better drink? relationships with total serum cholesterol in a cross-sectional survey. the nordland health study. | cross-sectional studies have not consistently shown a positive association between milk drinking and serum cholesterol. we studied this relationship in a cohort of 7506 men and women aged 40-42 years in the county of nordland in northern norway (72% of all subjects in the age-bracket living in the county). we found a positive relationship between the percentage of fat in the milk and total serum cholesterol, but no positive relationship between whole fat milk consumption (number of glasses per d ... | 2006 | 1475646 |
| architectonics of the parietal and temporal association cortex in the strepsirhine primate galago compared to the anthropoid primate macaca. | a number of higher order association areas have been described in the parietal and temporal cortex of large-brained anthropoid primates such as macaca. however, little is known about the evolution of these areas, and the existence of homologous areas has not yet been clearly demonstrated in other mammalian groups. we addressed this issue by comparing the myelo- and cytoarchitecture of posterior association cortex in the anthropoid macaca to that of the small-brained, strepsirhine ("prosimian") p ... | 2007 | 1939733 |
| seventh international meeting of the society for advancement of contraception. singapore, 4-11 november 1990. | | 2007 | 1950709 |
| regulation of alcohol consumption by the renin-angiotensin system: a review of recent findings and a possible mechanism of action. | the renin-angiotensin system has traditionally been associated with the regulation of fluid and electrolyte balance. in this review we summarize the data which ascribes a completely new function to this system, i.e., the regulation of alcohol consumption. in addition, we suggest a possible mechanism for this effect based on the concept of a satiety or stop process. the approach taken was to examine the effect on alcohol intake of a wide variety of drug, genetic, dietary, surgical and neurosurgic ... | 2007 | 1852316 |
| differential expression of the il-2 receptor subunits, p55 and p75 on various populations of primary peripheral blood mononuclear cells. | unstimulated pbl were examined for expression of il-2r subunits, il-2rp55 and il-2rp75, by two-color flow cytometric analyses using mab. nkh-1+ non-t non-b cells expressed il-2rp75 but not il-2rp55, and the il-2rp75 sites on purified nkh-1+ cells were determined to be 1630 sites/cell by binding of 125i-labeled tu27 mab specific for il-2rp75. in the cd4+ t cell population, il-2rp55+ cells were significantly detected, but little or marginally of the il-2rp75+ cells. however, il-2rp75+ cells were s ... | 2008 | 2584707 |
| recovery from coma that results as a complication of cardiac arrest followed by cardiopulmonary bypass. | many possible complications are associated with cardiopulmonary bypass. they are similar to the risks accompanying most surgical procedures and include stroke, renal failure, and death. this potential for complication increases when bypass exceeds 2 hours and rises sharply when pump time is prolonged more than 3 to 4 hours. one group of serious complications is major neurologic disorders. the risk of significant cerebral dysfunction, that is, severe focal stroke or coma, is about 1%, and this ri ... | 2008 | 2584045 |
| [clinical study of osteoporosis]. | | 2008 | 2614196 |
| construction of an ileal reservoir in patients with a previous straight endorectal ileal pull-through. | a decade has passed since martin and associates presented the first series of endorectal ileal pull-through (pt) procedures with straight ileoanal anastomosis for treatment of ulcerative colitis and polyposis. during the ensuing years, several medical centers have reported their results using the pt. although some children have experienced good results, the majority of adults and children have had severe problems associated with high stool frequency, urgency, and incontinence. between 1977 and 1 ... | 2009 | 2839124 |
| construction of an ileal reservoir in patients with a previous straight endorectal ileal pull-through. | a decade has passed since martin and associates presented the first series of endorectal ileal pull-through (pt) procedures with straight ileoanal anastomosis for treatment of ulcerative colitis and polyposis. during the ensuing years, several medical centers have reported their results using the pt. although some children have experienced good results, the majority of adults and children have had severe problems associated with high stool frequency, urgency, and incontinence. between 1977 and 1 ... | 2009 | 2839124 |
| hope for aids vaccines. | | 2009 | 2781299 |
| [plastic surgery in otorhinolaryngology: reconstruction flaps in oncologic surgery]. | | 2009 | 2701493 |
| longitudinal and cross-sectional assessments of age changes in physical strength as related to sex, social class, and mental ability. | | 2011 | 4833758 |
| initiation of blood coagulation at artificial surfaces. | | 2012 | 3439730 |
| [risks of postcoital contraception using a d-norgestrel-ethinyl estradiol combination]. | | 2013 | 3726780 |
| haemobilia from ruptured right hepatic artery aneurysm. a complication after aortic valve replacement. | | 2015 | 4547216 |
| retreatodontics and ultrasonics. | | 2011 | 3162934 |
| [surgical treatment of primary chronic pancreatitis]. | surgical methods of treatment of chronic alcoholic pancreatitis must be chosen with special reference to the state of the duct and parenchyma of the pancreas. treatment of alcoholic patients should be performed with the participation of psychiatrists. | 2012 | 3424549 |
| transcardiac passage of thrombus--ultrasonographic visualization. | a patient is described in whom a right atrial thrombus was seen, by two-dimensional echocardiography, in the act of embolizing into the pulmonary circulation. | 2009 | 2702500 |
| [essential arterial hypertension in patients with non-insulin-dependent diabetes mellitus during and after balneotherapy followed-up for 6 years]. | the statistical correlations between body weight, glycemia, total lipids, cholesterol in 200 patients with essential hypertension, especially borderline essential hypertension, followed up for 6 years indicate that the complex environmental factors in slănic-moldova health resort associated with balneotherapy may induce a return to normal values of the above mentioned parameters. good results were also obtained in the patients with essential hypertension and non-insulin dependent diabetes mellit ... | 2009 | 2636767 |
| plasma camp and renin in diabetics during insulin induced hypoglycemia. | | 2002 | 187538 |
| electrodiagnosis in peripheral nerve injury. | | 2002 | 135753 |
| myeloid and erythroid progenitor cells from normal bone marrow adhere to collagen type i. | one of the mechanisms by which normal hematopoietic progenitor cells remain localized within the bone marrow microenvironment is likely to involve adhesion of these cells to extracellular matrix (ecm) proteins. for example, there is evidence that uncommitted, hla-dr-negative progenitor cells and committed erythroid precursors (bfu-e) bind to fibronectin. however, fibronectin is not known to mediate binding of committed myeloid (granulocyte-macrophage) progenitors, raising the possibility that ot ... | 2004 | 1370640 |
| [measurement of orthodontic appliance force using prototype sensors]. | in introductory remarks the most important biomechanical principles, which are relevant for the research, and conditions which must be satisfied presented in intraoral measuring of orthodontic forces were pointed out. first the aim of the research was defined, and then the investigation of mechanical properties of acrylics as a material for orthodontic appliances were carried out. the type of strain gauges, bonds and measuring system configurations, as well as measuring amplifiers and recording ... | 2008 | 2635572 |
| 31p-nmr study on intracellular energy transport in muscle. | | 2009 | 2798486 |
| 31p-nmr study on intracellular energy transport in muscle. | | 2009 | 2798486 |
| the conus with no great artery. | in three patients with complex cyanotic congenital heart disease, the conus was found to have no arterial outlet. the semilunar valves were at similar, caudad levels, and there was malposition of the great arteries. the aorta was related to the body--not the outflow portion--of the right ventricle in two patients with transposition and to the body of the left ventricle in one child with single ventricle. these cases confirm the independent embryological segregation of the conus and the truncus. ... | 2011 | 3207481 |
| deficiency of eosinophil peroxidase detected by automated cytochemistry. | | 2011 | 3122494 |
| proceedings from a workshop symposium of the 14th international congress of chemotherapy. kyoto, japan, june 23-28, 1985. | | 2012 | 3510504 |
| cancer, stress and personality: a correlational investigation of life-events, repression-sensitization and locus of control. | this study investigated the hypothesis that stress-inducing life experiences and the personality factors of external locus of control and tendency to repress emotion are relevant in the aetiology of cancer. fifty cancer patients scored higher than 50 matched controls on a life-events scale (especially negative events), but were found to be lower on repression of emotion. there was no difference between groups on locus of control. | 2012 | 3401426 |
| an intrarenal foreign body. | | 2016 | 5041547 |
| hospital indicators. | | 2016 | 4820306 |
| a report on genetic registers. based on the report of the clinical genetics society working party. | | 1998 | 106123 |
| the effects of dihydrotachysterol therapy on the measurement of plasma 1,25-(oh)2-vitamin d in humans. | anephric patients have undetectable plasma concentrations of 1,25-(oh)2-d, but when anephric patients are treated with dht2 (hytakerol), their plasma contains a substance that is co-purified with and displaces authentic 3h-1,25(oh)2-d3 from its intestinal cytoplasmic receptor. the concentration of this substance in the plasma of anephric patients taking dht2 is proportional to the administered daily dose of dht2 per kilogram body weight. when dht2 therapy is discontinued, the substance disappear ... | 2004 | 438604 |
| rating of the lesions in senile dementia of the alzheimer type: concordance between laboratories. a european multicenter study under the auspices of eurage. | the study reported was intended to compare the impressions and analyses of investigators from 11 different laboratories on 2 slides, each from 6 cases with varying quantities of neuropathological change of the type found in alzheimer's disease and normal ageing. the material came from 6 selected female patients over 75 years of age all of whom had been examined in detail and assessed by the blessed test score. two were severely demented, 2 mildly demented and 2 were considered to be normal. unst ... | 2006 | 1698217 |
| preventing the kidney disease of diabetes mellitus: public health perspectives. | | 2007 | 2643304 |
| two cytochrome p-450 isoforms catalysing o-de-ethylation of ethoxycoumarin and ethoxyresorufin in higher plants. | the o-dealkylating activities of 7-ethoxycoumarin o-de-ethylase (ecod) and 7-ethoxyresorufin o-de-ethylase (erod) have been fluorimetrically detected in microsomes prepared from manganese-induced jerusalem artichoke tubers. cytochrome p-450 dependence of the reactions was demonstrated by light-reversed co inhibition, nadph-dependence, nadh-nadph synergism and by use of specific inhibitors: antibodies to nadph-cytochrome p-450 reductase, mechanism-based inactivators and tetcyclasis. apparent km v ... | 2008 | 2241905 |
| effects of early maturation on fetal growth. | while the association of young maternal age with low birthweight (lbw) is well known, the contribution of early menarche to this association has never been studied. we examined the effects of early menarche (less than or equal to 11 years) on lbw and its two major underlying causes: pre-term delivery and smallness-for-gestational-age (sga). results represent a narrow chronological age range, 17-18 years, of a larger geographically based cohort of 2789 pregnant adolescents. adjusted odds ratios ( ... | 2009 | 2782851 |
| allocation and the physician: the impacts of aging and aids. | | 2009 | 2709175 |
| serum levels of bilirubin and biliverdin in the sea lamprey, petromyzon marinus l., before and after their biliary atresia. | 1. the sera of ammocoetes, juvenile adults, and upstream migrants of the sea lamprey, petromyzon marinus l., were analyzed for the presence of the bile pigments, biliverdin and bilirubin. 2. bile pigment was not detected in the sera of ammocoetes. 3. after biliary atresia (degeneration of bile ducts at metamorphosis), bilirubin and biliverdin were detected in the sera of both juvenile adults and upstream migrants. 4. these data suggest that lampreys have some bile stasis following biliary atresi ... | 2010 | 2887360 |
| effects of momorcharins on ovarian response to gonadotropin-induced superovulation in mice. | alpha- and beta-momorcharins, which are abortifacient proteins isolated from momordica charantia seeds, were tested for a possible effect on ovulation and plasma levels of ovarian steroids in mice induced to superovulate by pmsg and hcg. the plant proteins did not affect follicular recruitment and maturation as evidenced by ovarian histology and serum 17 beta-estradiol level. both proteins diminished the number of oocytes ovulated when given on the day prior to or on the day of pmsg treatment, b ... | 2010 | 2898450 |