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protamine and polyarginine bacteriolysis. similarities in its mechanism with chromatin dna picnosis.protamine and polyarginine had bacteriolytic effects indicating their primary sites of action as being wall components and showing bacterial diversity genetically determined. shake-incubation was required in producing cell-lysis. studies on bacillus subtilis revealed a high polycation multiplicity per cell in lytic event displaying multihit lysing kinetics; bacteriolysis was inhibited by trypsin, pronase, purified polyanionic wall polysaccharide, and by dissociative actions of salt hypermolariti ...1979161838
detection of memory cells by chemical modification of the lymphocyte cell surface.stringent alloantigen requirements, necessary for the differentiation of human memory cells into specific secondary cytolytic t cells (2 degrees ctl), can be bypassed by chemical modification of memory cells with the mitogenic oxidising agent, galactose oxidase. treatment of memory cells generated in a long-term primary mixed lymphocyte culture with neuraminidase and galactose oxidase (nago) results in the differentiation of memory cells into 2 degrees ctl. in contrast, treatment of unprimed cel ...1979162003
the biogenesis of mitochondrial membranes in the yeast saccharomyces cerevisiae.membrane lipids of yeast mitochondria have been enriched by growing yeast cells in minimal medium supplemented with specific unsaturated fatty acids as the sole lipid supplement. using the activity of marker enzymes for the outer (kynurenine hydroxylase) and inner (cytochrome c oxidase and oligomycin-sensitive atpase) mitochondrial membranes, arrhenius plots have been constructed using both promitochondria and mitochondria obtained from o2-adapting cells in the presence of a second unsaturated f ...1975164216
phosphohydrolases: inorganic phosphate reaction giving stably stained zymograms using an alternative to benzidine. 2003165755
bone changes in congenital cytomegalic inclusion disease.1. while below 10 degrees c, the initial burst of pi liberation in the hydrolysis of mn(ii)-atp by heavy meromyosin or myosin subfragment 1 was inhibited by the pre-addition of adp without any change in the steady-state activity, it was not inhibited above 10 degrees c. the burst size was about one mole per two moles of myosin active sites. 2. above 10 degrees c, the ultraviolet absorption spectrum of heavy meromyosin induced by atp in mnc12 was similar to that induced in mgc12 and the spectral ...1975165786
cellular hypersensitivity to basic myelin (p2) protein in the guillain-barré syndrome.lymphocytes of 29 subjects were assayed for mif production in response to p2 peripheral nerve protein, crude human peripheral nerve and human central nervous system al basic myelin protein. seven were performed in normal control subjects, 12 in guillain-barre patients (gb), 5 with other polyneuropathies and 5 in patients with multiple sclerosis (ms). only gb patients with acute illness produced mif in response to neuritogenic p2 protein and crude human nerve. two ms patients in the acute phase o ...1975165869
[mechanism of giant cell formation in rfl-cells with infection of murine leukemia virus (author's transl)]. 1975166032
[steroid hormones and liver tumors]. 1975166047
action of cytochalasin d on cells of established lines. iii. zeiosis and movements at the cell surface.the projection of knobby protuberances at the cell surface (zeiosis) is a general cellular response to cytochalasin d (cd), resulting from herniation of endoplasm through undefended places of the cortex during cell contractions and displacement of microfilaments induced by cd. zeiosis is prevented by agents that interfere with the contractile response to cd, such as inhibitors of energy metabolism or cyclic amp. the developed protrusions, which remain relatively stable in the presence of cd, con ...1996168210
viral replication in human ovarian cell culture.a method is presented for the preparation and maintenance of human ovarian cell cultures. sections of normal ovaries removed at surgery were minced, trypsinized, and seeded as cell cultures grown in minimal essential media at 37 c. long-term, low-passage cultures were grown in quantities sufficient to permit viral studies. ovarian cells, of passage 23, were challenged with 57 known viruses. of these viruses, 52 (especially viruses of the picornavirus and adenovirus groups) produced typical cytop ...1975168524
structural studies on two adenovirus 2-sv40 hybrids containing the entire sv40 genome. 1975169085
[drug sensitivity of recently isolated bordetella pertussis and bordetella parapertussis]. 1975170435
[hydrogenase (author's transl)]. 1997170645
functional properties of mitochondria isolated from murine l5178 lymphoblasts grown in cell culture.mitochondria were isolated from lymphoblasts grown for 5 days in cell culture. measurement of mitochondrial respiratory activity revealed poor response to adenosine 5'-diphosphate with reduced nicotinamide adenine dinucleotide-linked substrates but well-coupled active respiration with succinate as substrate. these mitochondria also exhibited rapid initial rates of respiration-supported calcium uptake as measured by dual-beam spectrophotometry. h+/2e- and ca2+/2e- ratios were in normal limits for ...1988172230
effects of drugs and axotomy on acetylcholine levels in central cholinergic neurons.administration of cholinergic nuscarinic agonists either did not alter, or increased hippocampal ach levels, while antagonists lowered the levels. as observed previously, placement of lesions in the medial septal area resulted in a rise in hippocampal ach levels in the first thirty minutes. agonist drugs administered immediately before lesion, further increased the post-lesion rise in ach levels. with antagonists, inconsistent results were obtained in that atropine blocked the post-lesion rise, ...1975172807
the relationship between prostaglandin release and lung c-amp levels during anaphylaxis in the guinea-pig.a four-fold transient rise in c-amp levels was seen when sensitized guinea-pig lungs were challenged with antigen in vitro. this rise in c-amp also occurred in vivo and was shown to be due to release of prostaglandin e2. this conclusion is supported by the finding that inhibitors of prostaglandin synthesis (indomethacin and poly phloretin phosphate) prevent the rise in c-amp while neither ici 74, 917, an inhibitor of histamine release, nor antihistamines had any effect on the c-amp levels.1975172983
[cytological examination in the routine diagnosis of urethritis with inclusions]. 1995173008
antibodies to herpesvirus hominis types 1 and 2 among women with neoplastic change of uterine cervix.the occurrence of antibodies to herpesvirus hominis types 1 and 2 was studied in finland among patients with a neoplastic change of the uterine cervix. the following groups were studied: 220 patients with malignant or premalignant lesions of the uterine cervix, 143 control patients matched for age, socioeconomic level, marital status, home district and number of deliveries and 82 patients with breast or stomach cancer. antibodies to hvh types 1 and 2 were determined using the neutralization test ...1975173131
the cockerel as an animal model for atherosclerosis research.the chicken is a good animal model for the study of atherosclerosis research because it is: 1. omnivorous. 2. small and suitable for prolonged laboratory investigation. 3. able to develop spontaneous atherosclerosis. 4. capable of producing atherosclerosis after cholesterol feeding with elevated hypercholesterolemia. a diet of 1/4% cholesterol plus 5% cottonseed oil added to starter-grower-mash resulted in aortic atherosclerosis with a slight but significant increase in plasma cholesterol. 5. pl ...1975173152
human erythrocyte galactokinase and galactose-1-phosphate uridylyltransferase: a population survey.erythrocyte (rbc) galactokinase (galk) and galactose-1-phosphate uridylyl-transferase (galt) activities were measured in a random sample of 1,700 (1.082 black and 618 white) pregnant women from the philadelphia area to estimate the frequency of the genes galkg and galtg responsible for the two biochemically distinct forms of galactosemia. blacks have significantly lower mean rbc galk activities than whites (p less than .0005). the distribution of individual galk activities for blacks differs fro ...1975173184
[experimental investigations on the accumulation of radioactive compounds in autochtonal tumors in the rat (author's transl)].for the first time results of investigations on rats with radioactive compounds in autochtonal tumors of the central nervous system, induced via placenta by ethyl-nitrose-urea (enu), are reported. in contrast to transplantation tumors the tumors induced by enu are comparable in regard to the szintigrafic results with human brain tumors. the radiopharmaceuticals 131i-hsa, 99mtc-pertechnetate, 203hg-chlormerodrin and 113m/111in-dtpa are similar to human brain tumors taken up by the enu-tumors. for ...1975173256
hemagglutinating properties of celo, an oncogenic avian adenovirus.chicken-embryo-lethal-orphan (celo) virus, phelps strain, agglutinated erythrocytes at 37 c. the hemagglutinating activity, which is a function of complete and incomplete virus particles, was sensitive to heat but not to ph. the soluble components of the virus were similar in sedimentation characteristics to those obtained from human adenovirus type 1. the effects of chemical and physical agents on celo hemagglutinin, celo infectivity, and red-cell receptors suggested that the last were protein ...1975173279
inhibition of the binding of progesterone receptor to nuclei: effects of o-phenanthroline and rifamycin af/013. 1975173315
effect of calcium on cyclic amp-dependent and cyclic gmp-dependent endogenous protein phosphorylation in mouse brain cytosol. 1975173328
triiodothyronine binding proteins in rat liver cytosol. 1975173337
[studies on the influence of anticoagulants on metastase formation of autochthonic hepatomas in the rat (author's transl)].the frequency of metastases of malignant diethylnitrosamine-induced hepatomas and haemangioendotheliomas of the liver of female sprague-dawley rats (29%) was not influenced by application of acetyl-salicylic acid or phenprocoumon. likewise the anticoagulants did not alter tumor yields and induction periods.1975173350
editorial: depression and curtailment of sleep. 1995173447
evidence for 16alpha-hydroxylation of estrone 3-sulphate by guinea pig liver slices.[6,7-3h,35s]estrone 3-sulfate (e13s) of 3h/35s = 3.57 was incubated with female guinea pig liver slices. small amounts of free steroid and estrone-3-glucuronide, each containing 3h, were found. in addition, e13s, 17beta-estradiol 3-sulfate, and a 'disulfate' fraction, with 3h/35s = 4.4, 4.3, and 4.7, respectively, were also isolated from the incubated tissue. the latter fraction was a major metabolite and about 45% of it consisted of 'disulfates' of 16alpha-hydroxyestrone and estriol, thus provi ...1975173453
effects of levamisole and imidazole on lymphocyte proliferation and cyclic nucleotide levels. 1995173469
epidermal and other congenital organoid nevi. 1995173496
independent regulation of the nuclear and mitochondrial dna synthesis induced by either simian virus 40 or serum in mouse fibroblast 3t3 cells.resting cultures of 3t3 cells (an established line of mouse fibroblasts) were released from density inhibition by either infection with simian virus 40 or addition of serum. the increased rate of thymidine incorporation into dna, induced by these two agents, was measured in the presence and in the absence of three inhibitory conditions (cycloheximide or dibutyryladenosine 3':5'-monophosphate added to the medium, or lack of anchorage). the inhibition was found to be quite similar in cultures stim ...1975173546
structural studies on d-specific polysaccharide of shigella flexneri serotype 6. 1976173550
proceedings: separation of the "estrogen-induced protein" from phosphoprotein phosphatase activity of immature rat uteri.the distribution of phosphoprotein phosphatase (pppase) and estrogen-induced protein (ip) from 19- to 20-day-old rat uteri before and after fractionation of uterine cytosol, by ammonium sulfate, and by preparative cellulose acetate gel electrophoresis was studied. there was a lack of significant difference between the specific activity of pppase or its electrophoretic mobility in control extracts and those of extracts made 1 hour after injection of the rats with 5 mcg estradiol-17beta. most o ...1975173673
proceedings: energy requirement of the breakdown of rna in cultured hepatoma cells. 1995173680
proceedings: repression of cholinesterase production in pseudomonas aeruginosa by nh4+ and glucose and its prevention by cyclic amp. 1975173681
proceedings: pituitary plasma membrane-luteinizing hormone releasing hormone binding: evidence for the presence of specific binding sites in other tissues. 1975173780
proceedings: studies on the receptors to the odoriferous steroid, 5alpha-androst-16-en-3-one, in sow nasal epithelium. 1975173782
stoppage of glycogenesis and "over-shoot" of induction of lipogenesis and its related enzyme activities in the liver of fasted-refed rats.to elucidate the causes of changes of carbohydrate metabolic pathways, the time course of utilization of dietary [u-14c]sucrose and induction of enzyme activities in the livers of rats were investigated. adult male rats of bhe strain were refed after a fast of 2 days. the nutritionally complete refeeding diet contained 60% sucrose as the only source of carbohydrate. [u-14c]sucrose was included in the diet on either day 1 or day 2, or both of refeeding. during the first day of refeeding, the radi ...1976173817
proceedings: the role of the locus coeruleus in the acquisition of a conditioned avoidance response. 1975173834
response of c3h-avyfb female mice to a low oncogenic, milk-borne mammary tumor virus.when low oncogenic milk-borne mammary tumor virus (mtv) of strain dd was tested in c3h-avyfb mice, as compared with the similar strain c3hfb, mammary tumors occurred with a higher incidence and at lower age in c3h-avyfbfdd (with dd-mtv) than in c3hfbfdd (with dd-mtv), as observed in virgin females. since the effect of breeding tended to mask any difference between the breeders, mammary tumor incidences were similar with a slightly higher age at tumor occurrence in the c3h-avyfbfdd females. thus ...1975173862
[round-table discussion on plastic and reconstructive surgery improving function. speech perforamnce, grip performance of hand]. 1996173945
[carcinochemotherapy in pediatric surgery (author's transl)].one hundred sixteen children with malignant tumors were treated by surgery and additional chemotherapy from 1969 to 1974. the chemotherapy was standardized as far as possible for the commonest tumors of childhood (neuroblastoma, wilm's tumor rhabdomyosarcoma, osteosarcoma). the results are presented in detail.1996173946
general mediquiz. 1996173972
'glioblastoma'. induction of a reproducible autochonous tumor in rats with murine sarcoma virus.inoculation of 0.02 ml of high-titer kirsten strain murine sarcoma virus into the brains of 10-day-old wistar/furth rats yields, with 100 percent incidence, a uniform glioblastoma-like tumor within 16 days. light and electronmicroscopy confirmed the neuroectodermal origin of the parenchymal cells. the remarkable vascular component was studied with extracellular tracers. the permeability of the abnormal endothelium to constituents of the blood vascular compartment was confirmed. accessory vascula ...1976174026
a phase iii study in lung carcinoma comparing hexamethyl-melamine (nsc 13875) to dibromodulcitol (nsc 104800) 1,2.a phase iii study was designed comparing the effectiveness of hexamethyl-melamine (nsc 13875) to dibromodulcitol (nsc 104800) in lung carcinoma. 250 of the 316 patients entered on the study were stratified into groups according to stage of disease and cell type. the results showsed hexamethylmelamine to be more effective in patients with squamous cell carcinoma and slightly superior to dibromodulcitol in patients with anaplastic/undifferentiated cell carcinoma, whereas dibromodulcitol proved to ...1996174041
viral hepatitis--a primer: 1. epidem.iology.hepatitis a is most often transmitted by the fecal-oral route under conditions of crowding, poor hygiene, and prolonged exposure to infected persons. direct spread of hepatitis b via person-to person contact has only recently been proved. hepatitis b is usually transmitted indirectly proved. hepatitis b is usually transmitted indirectly by percutaneous routes, and the increase in drug abuse has brought about a change in its epidemiologic pattern.1976174067
on the iron-sulfur cluster in hydrogenase from clostridium pasteurianum w5.hydrogenase, purified to an average specific activity of 328 mumol of h2 evolved/(min x mg of protein) from clostridium pasteurianum w5, was found to have 4-5 fe and 4-5 labile sulfur atoms per molecule of 60,000 molecular weight, in contrast with earlier reports of 12 fe per molecule. displacement of the iron-sulfur cluster from hydrogenase by thiophenol in 80% hexamethyl phosphoramide:20% h2o yielded the fe4s4 (thiophenyl)4 dianion according to absorption spectroscopy. electron paramagnetic re ...1975174076
order of transcription of genes of vesicular stomatitis virus.the effect of ultraviolet radiation on the expression of the genes of vesicular stomatitis virus (vsv) was studied in a cell-free system which executed coupled transcription and translation of the viral genes. in this system, which contained detergent-activated virus and a cytoplasmic extract of mouse l-cells, three of the five viral proteins (n, ns, and m) were synthesized accurately and efficiently; a putative precursor to the viral glycoprotein (g) was also made, but synthesis of the l protei ...1976174107
association of cell surface receptors for melanotropin with the golgi region in mouse melanoma cells.binding of beta-melanotropin (betal-melanocyte stimulating hormone) to mouse melanoma cells occurs in a region on the cell surface overlying the golgi complex. this association was demonstrated by labeling cells with fluorescein isothiocyanate hormone and by locating the golgi complex with a histochemical test for thiamine pyrophosphatase activity. the biologically active fluorescent hormone appears on the surface and later in vesicles in the malanized cells, as judged by fluorescence microscopy ...1976174112
testing veterinary vaccines. 1975174269
[sensitivity of cells of the transplanted sheep kidney line to foot-and-mouth disease virus]. 1975174273
[diagnosis of adenovirus infection in man using fitz-immunoglobulins to whole virion and to the purified hexone component (author's transl)]. 1975174329
[several properties of the recruiting response]. 1975174338
differences in action of lh and fsh on the formation of cyclic amp in the prepubertal rat ovary.the actions of lh (nih-lh-b8) and fsh (nih-fsh-s9) on the cyclic amp (camp) system in ovaries of 23-24 day old rats have been analyzed. an intravenous injection of lh increased ovarian camp levels in vivo after only 20 seconds. maximal camp levels were seen after 15 min. addition of lh or fsh in vitro to the isolated ovaries produced dose dependent increases of camp in the tissue as well as in the incubation medium. low concentrations of lh caused a release of camp into the incubation medium wit ...1976174360
a simple competitive protein-binding assay for adenosine-3',5'-monophosphate in plasma and urine.a modified competitive protein-binding assay for the measurement of adenosine-3',5'-monophosphate is described. the procedure allows measurement of adenosine-3',5'-monophosphate in unextracted plasma samples. the mean plasma values in 25 normal, fasting and ambulatory subjects were 22.7 +/- 4.7 pmol/ml (mean +/- sd) (range 13-31 pmol/ml. the mean urinary content was 3.2 +/- 1.0 mumol per g creatinine (mean +/- sd) (n=24).1996174364
horizontally and vertically transmitted oncornaviruses of cats. 1975174397
hormone and prostaglandin e1 control of potassium and cyclic amp levels in isolated rat liver cells. 1975174402
contractile inactivation in frog single denervated muscle fibers.after preliminary conditioning depolarizations, single muscle fibers of the frog were tested for ability to contract in response to depolarization by 100 mm k+ ringer solution. denervated fibers (6-42 days) lose their ability to produce a 100 mm k+ contracture more rapidly than do control fibers. this decrease in 100 mm k+ contracture size (inactivation) is dependent on length of exposure to and magnitude of the conditioning depolarization and on the calcium concentration in the external medium. ...1996174446
hepatic metabolism of genetically diabetic (db/db) mice. i. carbohydrate metabolism.hepatic carbohydrate metabolism in genetically diabetic mice (db/db) and their normal littermates has been studied. in db/db mice, body water was below normal and declined with age. the liver of db/db mice was abnormally large in relation to the metabolic mass of the body at all ages studied. in db/db mice, hepatic glycogenolysis, glycogen synthesis, glycogen synthetase, and phosphorylase were markedly increased. gluconeogenesis from alanine or lactate in perfused livers of db/db mice was greate ...1975174448
ultrasound of the parotid gland.five cases of parotid gland masses were studied by ultrasound. only retention cysts and true cysts of the parotid gland appear sonolucent at low and high gain settings. benign and malignant tumor present as solid masses except for the warthin's tumor which is sonolucent at lower gain settings but has a lattice of internal echoes at higher gain settings.1997175095
[hypoglycemic syndromes]. 1997175257
the use of steroids in the treatment of idiopathic polyneuritis.the efficacy of steroids in the treatment of acute idiopathic polyneuritis (guillain-barré syndrome) continues to be uncertain. since 1965, 38 patients with idiopathic polyneuritis have been at the university of kentucky medical center, and 16 of them were entered in a prospective double blind study designed to assess the effectiveness of steroid therapy. seriously ill patients were excluded from the study and most of them received steroids. in both the double-blind group and the entire group of ...1997175314
[bronchopulmonary aspergilloma in children and bronchogenic cyst. a new case].the authors report a new case of aspergilloma developing in an intra-pulmonary bronchogenic cyst in a girl aged 10 years. a cure was obtained after surgical excision. the possibility of serious complications, such as hemoptysis, abscess formation and spread of the aspergillus, has two consequences; the first is the utility of regular supervision of any intra-pulmonary air cavity and, eventually, surgical removal. the second is the necessity of operation as soon as the diagnosis of aspergilloma h ...1975175446
[detection of anti-dna antibodies by electroimmunodiffusion. comparison of the results with the study of antinuclear factors by immunofluorescence].the detection of anti-dna antibodies was carried out by the electroimmunodiffusion method. the results were compared to those of the immunofluorescent method for anti-nuclear factors. positive results were obtained with the electroimmunodiffusion method in 86% of the lupus erythematosus cases, 77% of the sero-positive rhumatoid polyarthritis cases and 67% of the scleroderma cases. they are comparable to those obtained by other methods. the electroimmunodiffusion method allowed in 3 out of 54 ser ...1997175459
[gastric volvulus and absence of the left lobe of the liver]. 1997175501
[asthma caused by di-isocyanate]. 1997175535
[persistence of the foot-and-mouth disease virus in experimentally infected jackdaws]. 1975175553
[isolation and identification of autoimmune lipoprotein-antibody complex from blood serum of rabbits with experimental atherosclerosis]. 1975175569
[effect of hydrocortisone on lipid composition of blood serum lipoproteins in the development of experimental atherosclerosis].single administration of hydrocortisone into rabbits with experimental atherosclerosis increased the content of atherogenous classes of lipoproteins (low density lipoproteins (ldl) and very low density lipoproteins (vldl) in the animals with distinct atheromatosis. content of the lipoproteins was decreased in animals, which had no atheromatous alterations in aorta under the effect of atherogenous diet. within 5 hrs after the single administration of hydrocortisone in rabbits with pronounced athe ...1975175572
clinical and laboratory evaluation of epidemic keratoconjunctivitis due to adenovirus types 8 and 19.during a community outbreak of epidemic keratoconjunctivitis due to adenovirus types 8 and 19, we compared the clinical and laboratory characteristics of the two viruses. much of the disease was mild and the keratoconjunctivitis associated with adenovirus type 8 was indistinguishable clinically from that associated with adenovirus type 19. adenovirus type 8 was isolated only from the conjunctival sac, whereas adenovirus type 19 was frequently cultured from the nose, throat, and conjunctiva. the ...1976175659
angiography and ultrasonography. a comparative study of abdominal aortic aneurysms.ultrasound is presently the diagnostic procedure of choice in pulsatile abdominal masses. the ease and accuracy of this method have many advantages over aortography, and ultrasonography can accurately define the size of an abdominal aortic aneruysm. in addition, a normal aorta with an overlying mass, or a tortuous aorta which feels unusually prominent, can be detected, and aortography may not be necessary. although ultrasound can detect involvement of iliac arteries, it does not allow assessment ...1997175689
effect of temperature on the viability of bacillus stearothermophilus.one of the obligate thermophilic bacteria, bacillus stearothermophilus, was unable to grow at temperatures below 35 degrees c. about 80% of the population in the bacterial culture died at the temperatures, and the same extent of loss in either of the activities of oxygen consumption or synthesis of protein or nucleic acid of the organisms was observed. with the progress of death of the organisms, reduced nicotinamide-adenine dinucleotide came to be oxidized by the organisms, enzymes such as fruc ...1976175753
proceedings: macrophage adenyl cyclase tachyphylaxis-a new property of migration inhibitory factor. 1975176132
[restoration of the automatic contractile activity of k+-arrested heart muscle cells in culture by means of dibutyryl-3', 5'-adenosine monophosphate].cultured myocardial cells of new-born rats which were arrested by 17.6-37.6 mm kcl regained their ability to contract spontaneously after perfusion with 8-10(-4)-4-10(-3) m dibutyryl cyclic amp. this adrenaline-like action of dbcamp is compatible with the notion that cyclic amp is involved as a second messenger in the action of cyclic amp-raising adrenergic agents on cardiac activity.1975176854
striatal monoamines and reserpine and chlorpromazine rigidity. 1976178006
[aspects of the value of humoral antibodies in encephalomyelitis of neuroallergic origin].the importance of humoral antibodies formed in the course of neuroallergic diseases characterized by a cytergic type of reaction and especially in the course of experimental allergic encephalomyelitis (eaem) is discussed, special attention being given to the importance of pathogenetic, immunodynamic, diagnostic, and therapeutic factors. the circulating antibodies of eaem induced by cellular and humoral immunoprocesses are assumed to produce either intensifying or mitigating effects. among the mo ...1996178016
esr of hydrogen addition radicals in single crystals of 1-methylcytosine and 1-methyluracil. 1996178023
replication of human cytomegalovirus dna: lack of dependence on cell dna synthesis.human cytomegalovirus (cmv) dna synthesis was studied in 5-fluorouracil (fu)-treated and untreated human embryonic lung cells, which differ greatly with respect to the number of cells in the culture synthesizing cellular dna. cmv dna synthesis proceeded at the same rate in fu-treated and in untreated cells. cmv infection also reversed the inhibitory effects of fu and activated cellular dna synthesis in some of the cells in the fu-treated culture. autoradiographic studies showed that more than 20 ...1976178912
viral diseases of cats: current concepts. 1976179185
effect of aspirin and dexamethasone on intraocular pressure in primary uveitis produced by herpes simplex virus.the intracameral injection of new zealand white male rabbits with type 1 herpes simplex virus produced acute anterior uveitis with biphasic elevation of the intraocular pressure (iop). the first iop increase occurred on day 1 and 2 and the second increase on day 8. there was no significant correlation between the iop changes and multiplication of herpes simplex virus in the uvea and cornea, nor between the iop changes and histopathologic alteration of the tissue. aspirin suppressed significantly ...1976179324
hormonal variations in secondary amenorrhoea during the metyrapone test.the occurrence of uterine bleeding following administration of metyrapone in cases of secondary amenorrhoea and oligomenorrhoea led the authors to measure pituitary, gonadal and adrenal hormone levels, before and after the oral administration of this drug in sixteen patients, in an attempt to provide an interpretation of this phenomenon. there were expected changes in plasma acth and urinary 17-hydroxycorticosteroids, but no variations were noted in serum fsh and lh, plasma oestradiol and urinar ...1994186219
renal adenylate cyclase-effects of diuretics.the in vitro effect of various diuretics on rat kidney adenylate cyclase was investigated in crude homogenates of the cortex, the outer and inner medulla. 10-3 m furosemide inhibited adenylate cyclase by 40% in the cortex, by 16% in the outer medulla and by 43% in the inner medulla. 10-3 m ethacrynic acid inhibited adenylate cyclase activity by 65% in the cortex, 59% in the outer medulla and by 57% in the inner medulla. amiloride produced no significant inhibition of the adenylate cyclase reacti ...1975186272
effects of cytochalasin and alkaloid drugs on the biological expression of herpes simplex virus type 2 dna. 1976186287
3': 5'-nucleotide phosphodiesterase in the superior cervical ganglion of the rat. evidence for multiple forms and influence of the beta-adrenergic receptor system in the electrophoretic pattern of the enzyme.two forms of a camp phosphodiesterase were found in the superior cervical ganglia of the rat. the influence of various detergents on solubility and activity of the enzyme was studied. two km values were determined, one of 0.9mum and the other 270mum camp. separation by polyacrylamide disc electrophoresis revealed four distinct peaks of enzyme activity. one of these activities was increased when ganglia were incubated with adrenaline for at least 4 h. the increase caused by adrenaline was unaffec ...1976186378
safrole, isosafrole and dihydrosafrole. 1976186386
abnormal ultrastructural changes in sodium periodate-stimulated lymphocytes from patients with chronic lymphocytic leukemia.lymphocytoid and plasmacytoid blasts have been identified in both normal and chronic lymphocytic leukemia lymphocyte cultures exposed to naio4. however, the appearance of ultrastructurally abnormal blasts in chronic lymphocytic leukemia cultures suggests that naio4 also stimulates the transformation of an abnormal subpopulation of lymphocytes. development of invaginated nuclei produced morphological features similar to nuclear blebs, a cellular abnormally described in blood cells from other canc ...2003187326
is nimh's dream coming true? wyoming centers reduce state hospital admissions.do comprehensive community mental health services reduce admissions to state hospital? a recent nader report says no. surprisingly few studies have documented the success of comprehensive community mental health programs. wyoming had four unique characteristics that aided in evaluating the impact of centers on hospital admissions. the results of this study indicated that community-based comprehensive mental health services do, in fact, reduce psychiatric hospitalization.2003187372
isolation and some properties of mitochondria from the abdomen muscle of the crayfish orconectes limosus. 2003187373
plasma camp and renin in diabetics during insulin induced hypoglycemia. 2002187538
[principles of personnel management]. 1993187861
[isolation of preparations of type b monoamine oxidase from liver mitochondria]. 1977193582
using hospital staff to provide aftercare: kudos and criticism. 2003193775
adenovirus of ring-necked pheasants: purification and partial characterization of marble spleen disease virus.a method for purification of marble spleen disease virus (msdv) from the spleens of infected turkeys and pheasants is described. it combines chloroform or fluorocarbon extraction with subsequent purification by centrifugation on a cushion of cesium chloride (cscl). further purification of msdv was accomplished with a cscl equilibrium density gradient. a viral buoyant density of approximately 1.32 to 1.33 g/cm3 was determined. negative-stain electron microscopy revealed that virus isopycnically b ...1977193796
the storage lipids in tangier disease. a physical chemical study.the physical states and phase behavior of the lipids of the spleen, liver, and splenic artery from a 38-yr-old man with tangier disease were studied. many intracellular lipid droplets in the smectic liquid crystalline state were identified by polarizing microscopy in macrophages in both the spleen and liver, but not in the splenic artery. the droplets within individual cells melted sharply over a narrow temperature range, indicating a uniform lipid composition of the droplets of each cell. howev ...1977193870
purification and characterization of high-molecular-weight forms of adrenocorticotropic hormone of ovine pituitary glands.a highly purified preparation of high-molecular-weight adrenocorticotropic hormone (acth) was prepared from ovine pituitary glands by dilute acetic acid extraction, oxycellulose fractionation. sephadex gel filtration, and affinity chromatography on immobilized alphap(1-39)acth antibodies. two acth peptides of molecular weights of 24 000 and 34 000 were detected by sodium dodecyl sulfate-acrylamide gel electrophoresis in this preparation. it appeared that the immobilized antibodies adsorbed two f ...1977195594
on the mode of action of clonidine: relationship between effects on behaviour and cyclic nucleotide content in mouse brain. 1977196226
recent advances in the identification of hepatitis viruses.resulting directly from the discovery of virus-related antigens, rapid progress has marked the last decade of viral hepatitis research. the hepatitis b virion has been tentatively identified as a dna virus with an endogenous dna polymerase, and new serological markers for type b hepatitis have been discovered. hepatitis a antigen has been identified on a virus-like particle thought to be the hepatitis a virion. progressively more sophisticated assays for hepatitis antigens and antibodies have be ...1977196274
interaction between isoprenaline and aminophylline in asthma. 2003201045
[pathomorphology of infectious bursitis in chicks].morphologic studies were carried out on birds aged 17 to 90 days, affected with gumboro disease and occasionally died from the same disease (infectious bursitis). established were hemorrhages in the leg and breast musculature, substantial enlargement of the bursa of fabricius, and lesions in the kidneys. in some cases hemorrhages were also found on the serous membrane of the parenchymal organs. the histologic investigation of the involved parenchymal organs revealed necrobiotic changes (karyopyc ...1977201083
[after-care of surgical removal of wisdom teeth]. 2003201125
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