| specific requirement of nadph-cytochrome c reductase for the microsomal heme oxygenase reaction yielding biliverdin ix alpha. | | 1979 | 105935 |
| the effect of treatment with a polychlorinated-biphenyl mixture on hepatic and extrahepatic xenobiotic metabolism in the rat and ferret [proceedings]. | | 1978 | 105952 |
| passage of immunoglobulins from plasma to the oral cavity in rhesus monkeys. | the passage of immunoglobulin from plasma to the oral cavity was studied in rhesus monkeys. immunoglobulins g, a and m were purified from pooled rhesus monkey serum, radiolabelled with 125i and injected intravenously into twelve monkeys. sequential samples of oral fluids were taken over a 24 h period and were assayed for radioactivity. radioactivity could be detected in crevicular fluid washings after 0.5 h in monkeys injected with igg and iga, and after 2 h in monkeys given igm. maximal levels ... | 1978 | 104924 |
| p-hydroxyphenylacetaldoxime, an inhibitor of beta-galactosidase, produced by actinomycetes. | | 1979 | 104950 |
| isolation, homogeneity, and properties of core particle from pyocin r1. | by a mild alkaline treatment of pyocin r1, the core particle was released from the contracted sheath. after sucrose density-gradient centrifugation, core-rich fractions were treated with anti-sheath serum and by a second density-gradient centrifugation, purified core particles were isolated. homogeneity of the preparation was confirmed by observation under the electron microscope, immuno-precipitation reaction, and sucrose density-gradient centrifugation. the core particle exhibited a sedimentat ... | 1979 | 106048 |
| characterization of the extracellular lipase of bacillus subtilis and its relationship to a membrane-bound lipase found in a mutant strain. | bacillus subtilis cmk33 is a mutant that is more osmotically fragile than the wild type when it is converted to the protoplast form. the protoplasts of this mutant contain a membrane-bound lipase, which is not found in protoplasts of the wild type. hydrolysis of the membrane lipid of mutant protoplasts by the lipase is the cause of their fragility. a protein found in the wild type organism specifically inhibits the lipase (kent, c., and lennarz, w. j. (1972) proc. natl. acad. sci. u. s. a. 69, 2 ... | 1979 | 105000 |
| construction of a recombinant plasmid composed of b. subtilis leucine genes and a b. subtilis (natto) plasmid: its use as cloning vehicle in b. subtilis 168. | | 1978 | 105237 |
| [effect of polychlorinated biphenyls in the rat: ii.--preliminary report on metabolic alterations (author's transl)]. | rats were fed with a diet containing 10 and 100 ppm (wet weight) of phenoclor dpr for 4 weeks in order to evaluate the toxicity of a french pcb mixture. the influence of pcb was studied by determining the liver weights, the hepatic and muscular proteins, glycogen and humidity content as well as hematocrite, glucose, proteins and lipids in the plasma, and the lipidic contents of the liver and the carcass. there was a significant increase in both liver to body weight ratios and liver lipid and pro ... | 1978 | 105425 |
| characterization of a pituitary cell culture system derived from pregnant rats. | | 1979 | 106735 |
| polychlorinated biphenyls induced rat liver adenomas. | multiple liver adenomas were found in 30 month old female rats which had received for 28 months, 200 ppm polychlorinated biphenyls (arochlor 1254) in their drinking water. no lung metastases were detected. the examination of fragments of these adenomas under the electron microscope showed group polymorphism of the hyperplastic liver cells. the ultrastructural changes were considered to be as a result of chemical lesions induced by polychlorinated biphenyls and as adaptive morphological responses ... | 1978 | 105426 |
| [evolution and transformation in animal organism of some polychlorobiphenyls (author's transl)]. | intoxication by pure polychlorobiphenyls and a commercial product is studied, in rats, after intraperitoneal and oral administration. their fixation and excretion of their metabolites is greater by intraperitoneal than by oral administration. the only hydroxy metabolites, identified by means of synthesis, gas chromatography and mass spectrometry are, all, derivatives from trichlorobiphenyl. it appears that administration of commercial product induces a more rapid degradation of these compounds i ... | 1978 | 105430 |
| serological study of trichloroacetic acid extracts of bacteroides fragilis. | immunodiffusion techniques were used on trichloroacetic acid extracts from 10 strains of bacteroides fragilis in detecting precipitating antibodies against this species in immune rabbit sera. species and even strain specificities were observed in these precipitin reactions. multiple antigens were detected in the extracts from some strains, whereas only one precipitin band per extract developed during agar-gel diffusion tests of others. the antigen extracts were found to be both heat stable and r ... | 1979 | 107193 |
| insulin counteraction of alpha-adrenergic effects on liver glycogen metabolism. | insulin counteracted the effects of a pure alpha-adrenergic agonist, phenylephrine, on hepatocyte glycogen synthase and phosphorylase. these results argue against current concepts of insulin increasing cytoplasmic ca2+ concentration. | 1978 | 103580 |
| a new sequence-specific endonuclease from anabaena cylindrica. | | 1978 | 103749 |
| [effects of 5-hydroxytryptamine creatinine sulfate on development of the in vitro cultivated explants of the cerebrocortex of neonatal rats (author's transl)]. | explants of the cerebrocortex of neonatal rats were cultivated up to 15 div in addition to 5-hydroxytryptamine creatinine sulfate at the final concentration of 0.1 mm. fluorescence histochemical investigations were accomplished with a modified glyoxylic acid "heat reaction" according to lindvall and björklund (1974). depending on the duration of the cultivation and/or influence of the 5-hydroxytryptamine creatinine sulfate in varied fiber and cell elements of the explants varied effects were fou ... | 1978 | 105555 |
| multiple sclerosis: immunochemical studies on the demyelinating serum factor. | sera from patients with multiple sclerosis (ms) frequently produce demyelination of central nervous system tissue cultures. the nature of the factors responsible for demyelination is not as yet clearly established. however, several authors previously reported, in in vivo and in vitro models, demyelinating activity in igg fractions isolated from sera and cerebrospinal fluid of ms patients14,42,48. we found the demyelinating activity of ms sera to be extremely labile to conventional biochemical tr ... | 1979 | 105780 |
| thermostable antigens from the bone marrow of several animal species. | studies on bone marrow extracts from ten animal species have revealed the presence of thermostable antigens. similar antigens were found in other organs as shown by immunodiffusion and cross-reactivity was demonstrated between the thermostable proteins from horse and dog and between cow and sheep proteins. using an immunoenzymatic reaction with glucose oxidase as the marker, the thermostable antigens were localized in the blood and bone marrow polymorphonuclear leukocytes and the myeloid cell li ... | 1978 | 105786 |
| isolation of meningococci in meningococcal endophthalmitis. | we describe a case of bilateral hypopyon in a 7-year-old african male receiving systemic antibiotic therapy for meningococcal meningitis. aqueous from paracentesis of the left eye contained intra- and extra-cellular gram negative diplococci. we believe this is the first report of isolation of the organism since the advent of antibiotic treatment. | 1979 | 105789 |
| synchronous, sustained oscillation of c-peptide and insulin in the plasma of fasting monkeys. | the previously reported synchronous oscillations in plasma glucose and insulin levels have been further studied to determine whether the phenomenon can be attributed to cyclic secretion or degradation of the hormone. plasma c-peptide concentrations were measured and found to cycle with the same period as plasma insulin suggesting that the oscillations of insulin arise from changing secretion rather than degradation. the amplitude of c-peptide oscillation was 50 percent that of insulin. assuming ... | 1978 | 105880 |
| effects of trh and ergocryptine on mammary arterial and venous concentrations of growth hormone in lactating cows. | | 1979 | 107518 |
| [the immunhistochemical investigation of trypsin and trypsin-like-activity in the small intestine, pancreas and isolated langerhans islets. a light-, fluorescent- and electron microscopic study (author's transl)]. | by means of the indirect immunofluorescence and immunenzyme technique trypsin and trypsin-like activity in fixed cryostate sections of pancreas and gut and pellets of isolated pancreatic islets respectively were investigated using specific antiserum against trypsin. the enzyme was demonstrated in the cytoplasma of the acinus cells, the epithel cell of the intercalated ducts and the excretory (interlobular) ducts of the exocrine pancreas. by light and fluorescence microscopy we could also localiz ... | 1978 | 105556 |
| transport of oligomeric iga of systemic origin into external secretions. | | 1978 | 105568 |
| case report: intestinal clearance of calcium and protein in waldenstrom's macroglobulinemia. | a 63-year-old man with waldenstrom's macroglobulinemia had severe steatorrhea, marked protein-losing enteropathy, and excessive endogenous fecal calcium clearance. the malabsorption and protein loss resulted in weight loss and hypoalbuminemia. in contrast, the striking enteric calcium loss was completely compensated by an increase in calcium absorption resulting in a positive calcium balance. | 1978 | 105640 |
| [kinetics of the serological response in the experimental primary hydatid disease of mice infected with echinococcus granulosus embryophores (author's transl)]. | a serological response kinetics study was carried out in cf-1 mice orally infected with echinococcus granulosus embryophores using immuno-electrophoresis, double diffusion, latex agglutination and passive hemagglutination. starting from the 76th day after the infection, serum antibodies reach the minimum detectable level by immunoelectrophoresis test. band number 5, now considered as specific for e. granulosus, was proved to be the first precipitating system exhibited in this test. double diffus ... | 1978 | 105664 |
| relationship between biotin-binding proteins from chicken plasma and egg yolk. | the plasma of laying hens contains a specific biotin-binding protein that appears to be identical with an egg-yolk biotin-binding protein. both proteins are saturated with biotin and require elevated temperatures to effect the exchange of [14c]biotin for the protein-bound vitamin. the heat-exchange curve in each case is the same and differs sharply from that of avidin, the egg-white biotin-binding protein. on sephadex g-100 gel filtration, plasma and yolk biotin-binding proteins were each eluted ... | 1978 | 105724 |
| unique conformational properties of muscle carbonic anhydrase iii as demonstrated by circular dichroism spectrometry. | | 1979 | 105751 |
| nonenteric gram negatives, 1976. | | 1979 | 109001 |
| comparative in vivo nitrogen-15 nuclear magnetic resonance study of the cell wall components of five gram-positive bacteria. | the proton-decoupled 9.12 mhz 15n nmr spectra of 15n-labeled bacillus subtilis, bacillus licheniformis, staphylococcus auresu, streptococcus faecalis, and micrococcus lysodeikticus intact cells, isolated cells walls, and cell wall digests have been examined. the general characteristics of gram-positive bacteria 15n nmr spectra and described and spectral assignments are provided, which allow in vivo 15n nmr to be applied to a wide range of problems in bacterial cell wall research. the qualitative ... | 1979 | 105756 |
| membrane changes during growth of tetrahymena in the presence of ethanol. | after a brief lag period for acclimation, tetrahymena pyriformis, strain nt-1, is capable of growing in culture medium containing high levels of ethanol. when grown in a medium having 1.6% ethanol, the membrane phospholipid composition was significantly different from that of control cells. the principal changes included a reduction in hexadecenoic acids (16 : 1 and 16 : 2) from 23% to 5% and an increase in linoleic acid (18 : 2) from 14% to 25% similar but less pronounced changes were observed ... | 1979 | 105757 |
| precipitating antibodies against e. coli, b. fragilis, and p. aeruginosa in cf patients and normal persons determined by means of crossed immunoelectrophoresis. | | 1979 | 111037 |
| [changes in certain biochemical parameters of rat skin following prolonged gamma irradiation after radioprotection]. | | 1978 | 106409 |
| tk polyagglutination associated with reduced a and h activity. | tk polyagglutinable erythrocytes are described in which a and h activities were reduced. it is suggested that bacteroides fragilis isolated from cultures of the patient's blood was responsible for each of these membrane modifications. | 1978 | 106548 |
| [isolation of treponemas from the colon of pigs with clinical dysentery]. | optimal culture conditions in artificial nutritive media were determined for a defined avirulent strain of treponema hyodysenteriae and for four field strains of treponemas in pigs with clinical dysentery. the treponemas were isolated with the use of milliporous filters with pores of 0.3 micrometer in diameter, which were located on the surface of blood agar. no significant difference in the influence of equine, bovine or sheep blood on the growth of treponemas was determined. the commercial amo ... | 1979 | 105448 |
| bacteriology of acute pelvic inflammatory disease. suboptimal survival of neisseria gonorrhoeae in a nonbuffered transport system. | in our earlier study, neisseria gonorrhoeae was infrequently isolated while bacteroides fragilis was totally absent from cul-de-sac aspirates of patients with acute pelvic inflammatory disease (pid). twenty additional women were studied to further elucidate the bacteriology of this disease. recovery rate of n. gonorrhoeae from cul-de-sac aspirates collected in selective transport medium (transgrow) was 25 per cent among patients with gonococcal pid, compared to only 8 per cent when specimens wer ... | 1979 | 107802 |
| transfer of multiple antibiotic resistance between subspecies of bacteroides fragilis. | resistance to clindamycin, erythromycin, streptogramins, and tetracycline was shown to be transferable from a clinical isolate of bacteroides fragilis subspecies distasonis to a sensitive strain of b. fragilis subspecies fragilis. resistance to clindamycin, erythromycin, and streptogramins was transferable from a clinical isolate of b. fragilis subspecies fragilis to the sensitive strain of b. fragilis subspecies fragilis. except for tetracycline, resistance to all of these antibiotics was spont ... | 1979 | 108340 |
| growth and food intake of prematurely weaned rats: effect of cortisone and thyroxine injection during the suckling period. | | 1979 | 108369 |
| dietary modification of amphetamine stereotyped behaviour: the action of tryptophan, methionine, and lysine. | rats fed diets high in tryptophan, methionine, and tryptophan plus methionine or lysine were subsequently injected with 10 mg/kg d-amphetamine. the amount of amphetamine-induced stereotyped behaviour observed varied as a function of the dietary addition, with methionine showing the greatest difference to controls, and lysine the least. whole brain catecholamine levels and 5-hydroxytryptamine levels also showed amino acid-specific changes. | 1979 | 108724 |
| dissociation of autonomic and cognitive effects of thc in man. | intravenous thc, 30--44.8 microgram/kg, was administered to four subjects. each received thc on four occasions preceded by either i.v. saline, 0.04 mg/kg atropine sulfate, 0.2 mg/kg propranolol, or both drugs together. heart rates, subjective intoxication and symptom ratings, time productions, and eeg activity were measured. in the absence of autonomic blocking drugs, thc produced characteristic tachycardia, subjective intoxication, and eeg effects. after combined autonomic blockade, thc had no ... | 1979 | 108734 |
| exclusion of vha and vhy loci expression on individual b cells from normal and vh allotype-suppressed rabbits. | the distribution of two heavy chain subgroups, vha and vhy, on rabbit peripheral blood lymphocytes was examined by double membrane immunofluorescence. fluroescent anti-a1 and anti-y33 were found to react with separate b cell populations; no doubly stained cells were observed. further evidence for the independent expression of genes controlling the vha and vhy subgroups were obtained by neonatal suppression of a 2 or y33 in a2y33/a3y- heterozygous rabbits. suppression of vha did not affect the ex ... | 1979 | 108111 |
| thyroxine inactivation by starvation in cultured hepatocarcinoma cells, formation of reverse triiodothyronine. | the effect of starvation on thyroid hormone metabolism was studied in monkey hepatocarcinoma monolayer cultures. nonphenolic ring monodeiodination of thyroxine, 3, 5, 3'-triiodothyronine and 3, 3'-diiodothyronine was accelerated. since phenolic ring deiodination of 3, 3',5'-triiodothyronine (reverse t3) was unaffected, this metabolite accumulated in the medium during thyroxine metabolism. this suggests that increased serum reverse t3 in malnourished humans may be caused by enhanced deiodination ... | 1978 | 105981 |
| anti-kappa/lambda immunobead for detection of human b lymphocytes. | several methods were compared for quantitating the b lymphocytes in human peripheral blood. rbc rosette assays including sheep and bovine red blood cells, and immunobead rosette assays including beads coated with anti-kappalambda and trivalent anti-gam antibodies respectively were investigated. the anti-kappalambda bead assay proved to be simpler, faster, higher in reproducibility, and appeared to be more accurate than any of the other assays. | 1978 | 105987 |
| a monolayer study of the reaction of trinitrobenzene sulphonic acid with amino phospholipids. | the reaction of trinitrobenzene sulphonic acid with amino phospholipids, and in particular phosphatidylethanolamine has been studied by the monolayer technique. injection of trinitrobenzene sulphonic acid under a monolayer of amino phospholipid results in an increase in surface pressure. the rate and extent of the pressure change is greatly affected by the initial surface pressure, the fatty acid composition of the lipid, and the presence of other non-reactive lipids, especially negatively charg ... | 1979 | 106889 |
| affinity chromatography of endoglucanase of trichoderma viride by concanavalin a-agarose. | endoglucanase (c kappa cellulase) and cellobiase are often cross-contaminated in separation procedures by ion-exchange chromatography such as deae-cellulose. by using concanavalian a (con a)-agarose chromatography, c kappa cellulase and cellobiase from trichoderma virde can be separated. c kappa cellulase showed affinity toward con a. indicating a glycoprotein containing alpha-d-mannopyransyl and alpha-d-glucopyranosyl end groups or internal 2-o-d-mannopyranosyl residues in sugar moieties. this ... | 1979 | 106904 |
| suppression of uterine motor activity by prostaglandin synthetase inhibitor naproxen. | rats were ovariectomized on day 16 of pregnancy and they were fitted with a pressure sensor uterine microballoon assembly and were given a daily dose of naproxen-sodium. daily uterine activity recordings were taken and subjected to statistical analysis and the rats were carefully checked for either aborting or delivering their fetuses. our data showed that naproxen treatment effectively and significantly prevented the autocatalytic evolution of the uterine motor activity and the regulatory "see- ... | 1978 | 105529 |
| macaca assamensis as a new host for experimental plasmodium knowlesi infection. | | 1978 | 108217 |
| precipitating antibodies against escherichia coli, bacteroides fragilis ss. thetaiotaomicron and pseudomonas aeruginosa in serum from normal persons and cystic fibrosis patients, determined by means of crossed immunoelectrophoresis. | | 1979 | 111468 |
| [cholangiogenic bacteroides sepsis]. | | 1979 | 112392 |
| limitations of aeruginocine typing of ps. aeruginosa as an epidemiological marker. | | 1978 | 108218 |
| the in vitro activity of mezlocillin when combined with cefoxitin or clavulanic acid. | | 1979 | 113377 |
| sodium dodecyl sulphate--polyacrylamide gel electrophoresis of cell-surface proteins as an aid to the identification of the bacteroides fragilis group. | the outer-membrane complexes from 40 strains of bacteroides, representing eight of the species included in the bacteroides fragilis group, were released by edta treatment. the component polypeptides were examined by sodium dodecyl sulphate-polyacrylamide gel electrophoresis on slab gels. within a species (biotype) the patterns produced indicated marked similarities in the structures of the surface proteins among the strains examined. the patterns produced by strains belonging to different specie ... | 1979 | 113487 |
| bacteriology of rattlesnake venom and implications for therapy. | although the incidence of infection secondary to the bites of venomous snakes remains unknown, the routine use of prophylactic antimicrobial therapy is advocated. in this study, the venom from 15 rattlesnakes was cultured, and 58 aerobic and 28 anaerobic strains of bacteria were isolated. the most common species isolated were pseudomonas aeruginosa, proteus species, coagulase-negative staphylocci, and clostridium species. bacteroides fragilis was also recovered. when the fang sheaths of four add ... | 1979 | 119002 |
| [clinical bacteriological studies on the beta-lactamase produced by bacteroides fragilis (author's transl)]. | | 1979 | 119017 |
| the influence of attending on seizure activity in epileptic monkeys. | six studies are presented on the influence of attending upon epileptic activity in the alumina-gel monkey model of focal motor and secondarily generalized tonic--clonic seizures. seizure frequency and eeg paroxysms are reported during (a) scheduled feeding periods, (b) visual attending, and (c) three different operant tasks, including the conditioning of single neurons. an explanatory hypothesis of the cumulative data is proposed in terms of the different bursting behavior of group 1 (strongly e ... | 1979 | 110584 |
| creutzfeld-jakob disease and corneal grafts. | the possible danger of surgical transmission of creutzfeld-jakob disease from one human being to another has been reported in three instances. although laboratory attempts at transmission of this disease by corneal grafting have so far failed in animals, it is emphasized that great care should be exercised in the selection of donor material for corneal grafts and renal transplants. | 1979 | 111011 |
| [prevention of sequelae after transcutaneous radiotherapy for epitheliomas of the oral cavity (author's transl)]. | close cooperation between the radiotherapist, surgeon, and patient is necessary in order to prevent sequelae following transcutaneous radiotherapy for epitheliomas of the oral cavity. the most effective therapeutic results combined with a minimum of sequelae are obtained by the use of a good irradiation technique, close supervision, careful treatment of any oral or dental affection, prescribing simple medications only, and stopping the use of tobacco and alcohol. | 1979 | 111344 |
| an animal model of intra-abdominal sepsis. | | 1979 | 111347 |
| betamethasone and the rhesus fetus: multisystemic effects. | in this controlled study of betamethasone administration to pregnant rhesus monkeys, using dosages per gram of fetal body weight similar to those reported in several human clinical studies, the most significant fetal pulmonary changes observed were increases in maximum lung volumes. the fact that comparable increases in peak volumes were demonstrated on saline filling supports our contention that these changes are related primarily to lung structural alterations rather than surfactant effects. a ... | 1979 | 106730 |
| [human myeloma igg-kappa half-molecules: a case study (author's transl)]. | | 1979 | 116015 |
| the etiology of acute pelvic inflammatory disease. | | 1979 | 116376 |
| cryosurgery of major and minor salivary gland: a light microscopic evaluation in the rhesus monkey. | the minor salivary glands in the hard palate and the submandibular gland of the rhesus monkey were subjected to a liquid nitrogen, direct-spray, one-cycle freeze. a 4-min freeze in the temperature range of -40 degrees c to -60 degrees c was used. the extent of tissue destruction was determined at intervals up to 1 year. clinically relevant findings resulted and form the basis for subsequent studies by this group of investigators. | 1979 | 115981 |
| clinical and microbiologic surveillance of neonatal staphylococcal disease. relationship to hexachlorophene whole-body bathing. | neonatal staphylococcal disease occurred in the nurseries of a university hospital three weeks after discontinuation of routine, daily, whole-body bathing of newborns with hexachlorophene. of 16 infants who had clinical manifestations within a two-week period, 11 cases were confirmed bacteriologically. shortly after onset of the outbreak, daily clinical and microbiologic surveillance and control measures on all infants and personnel were inaugurated. clinical surveillance after the outbreak did ... | 1975 | 123704 |
| liver abscess complicating embolization of focal nodular hyperplasia. | | 1979 | 114026 |
| a craniometric study of the black and white colobus illiger 1811 (primates: ceropithecoidea). | this study examines the craniometry of black and white colobus monkeys using 1072 specimens representing all the recognized subspecies (after rahm, '70) of the genus. seventy-six measurements were taken on each individual, and examined using canonical variates analysis and clustering by ward's error sum method. the assumptions of the analytical techniques are shown to be met, and the results demonstrated to be stable. examination of the populations for statistical difference and taxonomic distin ... | 1979 | 114059 |
| frequency and fate of human renal allografts contaminated prior to transplantation. | bacterial cultures were done from donor ureter and/or graft perfusion fluid on 92 of 112 patients who had renal transplantations during 1977. three samples of perfusion fluid and 14 samples of donor ureter contained bacteria. in nine cases there was a gram-positive organism, and in 10 cases a gram-negative rod was (among) the contaminant(s). there was no difference in the rate of graft survival, patient survival, or in the frequency of major postoperative complications between the two groups. on ... | 1979 | 107605 |
| altered hypothalamic-pituitary regulation of thyrotropin in male rats during aging. | | 1979 | 108086 |
| [preventive and therapeutic application possibilities of newer antibiotics (author's transl)]. | today, however aminoglycosides are nearly indispensable owing to their broad antibacterial spectrum and genuine bactericidal effect as well as the possible synergic effect with beta-lactam preparations. the new cephalosporins are distinguished by a high beta-lactam stability and are active against the majority of pathogens causing nosocomial infections. an exceptional position is held by cefotaxim with its generally outstanding antibacterial potency, and by cefoxitin with its activity against ba ... | 1979 | 114782 |
| experimental infections with staphylococcus aureus, streptococcus sanguis, pseudomonas aeruginosa, and bacteroides fragilis in the jaws of dogs. | | 1979 | 114906 |
| histochemical patterns in human breast tumours. | histochemical investigations carried out on 104 breast tumours (10 benign proliferations and 94 carcinomas) showed that breast carcinomas were characterized by various enzymological equipments in relation to tumour differentiation degree, histogenesis, functional stage, site of tumour cells in the carcinomatous islands or cords and to hormonal factors. tumour cells -- stroma interrelationships study pointed out that high glycolysis (high ldh, nadph2-tr, nadh2-tr activities) and an intense lepa-a ... | 1979 | 115209 |
| [renewed appearance of penicillinase-forming neisseria gonorrhoeae in germany]. | | 1979 | 111433 |
| influence of neomycin and metronidazole on colonic microflora of volunteers. | the influence on colonic microflora of neomycin and metronidazole alone, or in combination, was studied in volunteers taking a normal diet. bacterial counts on daily faecal samples revealed that metronidazole had no influence on anaerobic faecal bacteria. neomycin on the other hand, was effective against sensitive aerobes. however, the combination of neomycin and metronidazole profoundly reduced both aerobic and bacteria. assay of faecal antibiotic concentrations showed that neomycin achieved hi ... | 1979 | 115830 |
| effects of methamphetamine and scopolamine on variability of response location. | methamphetamine and scopolamine were studied in monkeys responding under a multiple fixed-ratio fixed-interval schedule of reinforcement. a response on any one of six levers could satisfy the schedule requirements. variability of response location was evaluated in terms of switches, where a switch was defined as a response on one lever followed by a response on a different lever. under baseline conditions the fixed-ratio schedule generated a high rate of responding and a low level of variability ... | 1979 | 115956 |
| in vitro study of clavulanic acid in combination with penicillin, amoxycillin, and carbenicillin. | the activity of clavulanic acid alone and in combination with penicillin, amoxycillin, and carbenicillin was studied. marked reductions in the minimum inhibitory concentrations (mics) for a wide spectrum of beta-lactamase-producing clinical isolates were found. of particular interest were the decreased mics of penicillin for bacteroides fragilis and beta-lactamase-producing strains of neisseria gonorrhoea in the presence of the clavulanic acid. beta-lactamase-producing strains of escherichia col ... | 1978 | 122520 |
| folacin deficiency and requirement in the squirrel monkey (saimiri sciuresus). | acute folacin deficiency was studied in eight young squirrel monkeys (saimiri sciureus). half of the animals were fed a semipurified deficient diet (no added folic acid) and half were fed a control diet (0.84 mg of added folic acid per kilogram of dry diet). monkeys fed the deficient diet lost weight and suffered from diarrhea and dehydration leading to the death of one of the animals after 6 weeks. folacin deficiency also was studied in six older animals fed diets containing varying levels of a ... | 1979 | 116540 |
| isolation and characterization of recombinant dna plasmids carrying drosophila trna genes. | recombinant plasmids carrying drosophila melanogaster trna genes were constructed by ligation of hindiii-cleaved drosophila dna to hindiii cut pbr322 dna. 90 clones were isolated that contained genes for one or more of eleven trnas. 43 of the plasmids were characterized by a number of methods: restriction nuclease digestion; agarose gel electrophoresis; hybridization with individual, purified, 125i-labelled drosophila trna molecules and in situ hybridization to drosophila chromosomes. the result ... | 1979 | 118082 |
| pediatric osteomyelitis: iii. anaerobic microorganisms. | primary osteomyelitis consequent to obligate anaerobic microorganisms represents an infrequently encountered type of infection in pediatric patients. unlike osteomyelitis caused by more common microorganisms such as staphylococcus, children with osseous lesions due to anaerobic microorganisms are frequently minimally symptomatic and rarely present the classic signs of fulminant osteomyelitis. radiographically, the lesions may mimic malignant osseous tumors. fastidious microbiologic analysis of t ... | 1979 | 119602 |
| does bacteroides fragilis cause septic shock in primates? | | 1979 | 120028 |
| methionine transport in pseudomonas aeruginosa. | a high-affinity (km = 2.7 x 10(-7) m) energy-requiring methionine-transport system has been characterized in rm 46 and rm 48, two different pao methionine auxotrophs of pseudomonas aeruginosa. after 8 s of transport 40--60% of the methionine label in the alcohol extract appears in s-adenosyl-l-methionine (sam) with the remaining activity in free methionine. methionine transport required a high degree of structural specificity for transport. stimulation of transport occurred by addition of glucos ... | 1979 | 120222 |
| nervous functioning during ontogenesis: facts and reflections. | | 1979 | 120624 |
| chemotaxis by lipids isolated from bacteroides fragilis. | living, heat or formalin killed bacteroides fragilis and a crude preparation of their cell walls were examined by the boyden technique for chemotactic activity upon guinea pig peritoneal exudate cells. their relative chemotactic activity ranged from 3.0 to 5.2 compared to an average value of 6.4 for the positive control, an endotoxic culture filtrate of escherichia coli. a culture filtrate of b. fragilis and an index of 3.7. miocrogram quantities of cytoplasmic preparations obtained by ammonium ... | 1979 | 122317 |
| piperacillin, a new penicillin active against many bacteria resistant to other penicillins. | the in vitro activity of piperacillin, a new semisynthetic piperazine penicillin derivative, was evaluated against 626 clinical isolates and compared with the activity of other beta-lactam antibiotics. at a concentration of 0.1 microgram/ml, piperacillin inhibited all streptococci except enterococci. non-beta-lactamase-producing staphylococci were inhibited by 1.6 microgram or less per ml. both beta-lactamase- and non-beta-lactamase-producing haemophilus were inhibited by 0.1 microgram/ml. piper ... | 1978 | 122519 |
| biologic activity of soluble collagen-anticollagen immune complexes as demonstrated by passive cutaneous anaphylaxis. | collagen-anticollagen immune complexes were prepared by gel filtration. complex formation was chemically and serologically demonstrated. complexes eluting in gammam- and gammag-peaks of antigen-antiserum mixture showed strong positive reactions in pca experiments performed with 20 guinea pigs. control preparations of gammam- and gammag-peaks of antiserum devoid of antigen gave significantly lower pca-response. the positive reaction of control preparations can be explained in part by a certain de ... | 1975 | 127469 |
| repeated pulmonary thromboembolism in rabbits. | ten rabbits received 24 to 76 intravenous injections of finely divided thrombi prepared by a modification of chandler's apparatus. eight rabbits were killed soon after the last injection (group a) and two rabbits were allowed to survive for 4 months after the last introduction of thrombi (group b). ten rabbits received repeated saline injections only, and six animals underwent no manipulation whatever. six test rabbits and six control rabbits underwent catheterization of the pulmonary artery. th ... | 1975 | 123612 |
| [homologous transplants in the middle ear (author's transl)]. | the original concept of tympanoplasty included besides the closure of the middle ear, the removal of pathological middle ear components leaving intact the functional and healthy components. the special conditions that prevail in the middle ear (aeration, absence of intrinsic trauma) allow the reconstruction of the middle ear mechanics to a great extent. animal experiments and clinical experience reveal good transplantation properties of denatured and preserved ear ossicles. they are partly repla ... | 1975 | 123985 |
| [androgen metabolism and leydig-cell function in acute and chronic liver disease (author's transl)]. | diurnal variations of plasma testosterone and urinary excretion rates of testosterone-, androsterone-, aetiocholanolone-, and dha-glucuronide, as well as dha-sulphate were measured before and after selective leydig-cell stimulation (with 3 x 5000 iu human gonadotrophin) in eight patients with alcoholic liver cirrhosis, ten with acute hepatitis and four with haemochromatosis. the circadian variation of plasma testosterone and the maximal testosterone concentration after human gonadotrophin stimul ... | 1975 | 127698 |
| [proceedings: the myocardial efficiency of the hypertonic heart--bases for evaluations and typical misinterpretations]. | | 1975 | 128243 |
| histochemistry and histoenzymology of the hydatid cyst (echinococcus granulosus batsch, 1786). ii. scolices and brood capsules. | scolices and brood capsules of healthy hydatid cysts from lungs of human patients were studied with histochemical and histoenzymatic methods. the subtegumental and flame cells were sepcially rich in glycogen, rna and some dehydrogenases such as sdh, mdh, nadh-reductase and g-6-pdh. the rostellar zone or invaginated pole, an area of marked contractile movements, showed intense activity in atp'ase and simple esterase. the so-called excretory pole shows strong activity in simple esterases, lipase, ... | 1975 | 130750 |
| [histochemical study of carbonic anhydrase and hco3(-)-stimulated adenosine triphosphatase in the rat stomach during hydrochloric acid secretion]. | by means of histochemical methods it was established that carboanhydrase of the parietal cells of fundal glands and hco-3 stimulated atp-ase of the rat's gastric mucosa capillaries disposed next to the parietal cells were activated by food and histamine. the obtained data confirm the idea of the multicellular functional essembly sustaining hcl secretion (r. i. salganik, 1974). should gastrin induce the formation of histamine in endocrinous cells and the histamine activate carboanhydrase in parie ... | 1976 | 130854 |
| amino-acid sequence of the cyanogen-bromide fragment from human plasminogen that forms the linkage between the plasmin chains. | the complete amino acid sequence of a cyanogen bromide fragment (122 residues) obtained from plasminogen is described. this fragment forms the overlap between heavy (a) and light (b) chains of human plasmin. the particular arginyl-valyl bond cleaved in the second step of the activation process is shown to be arg98-val99 in this fragment. this site is not very similar to the one in the nh2-terminal part of the molecule (arg68-met69). remarkable homologies with the 'triple loops' ('kringle structu ... | 1975 | 126863 |
| [nuclei of the mammillary bodies and their fiber connections in cattle (bos taurus var. domesticus). i. nuclei of the mammillary bodies in cattle]. | 1. in the present neuroanatomic study the topography and cytoarchitectonic of the nuclei of the mamillary body of cattle are described and quantitative-morphologically investigated in 14 series of brains (6 frontal, 4 sagittal and 4 horizontal series, stained by the methods after nissl, klüver and barrera and after heidenhain). 2. the medial mamillary nucleus of cattle is with an average volume of 47.7 mm3 the largest nucleus of the mamillary body. it contains about 715,000 cells with a cell den ... | 1978 | 107664 |
| acyl-coenzyme-a synthetase i from candida lipolytica. purification, properties and immunochemical studies. | acyl-coenzyme-a synthetase i from candida lipolytica has been purified to homogeneity as evidenced by polyacrylamide gel electrophoresis in the presence and absence of dodecylsulfate as well as by ouchterlony double-diffusion analysis. the purification procedure involves resolution of cellular particles with triton x-100 and chromatography on phosphocellulose, blue-sepharose and sephadex g-100. the purified enzyme exhibits a specific activity of 20--24 u/mg protein at 25 degree c, which is about ... | 1979 | 108099 |
| effects of urinary proteins from certain leukemics upon macromolecular synthesis and enzyme levels in bone marrow cultures. | urinary proteins from human leukemic patients have been found to alter quantitatively macromolecular synthesis in primary mouse bone marrow cultures. urinary protein-stimulated incorporation of [3h]uridine into rna was found after 1 day of culture. increased levels of adenine phosphoribosyltransferase and lysozyme were demonstrable at 3 and 5 days, respectively, with urinary protein-supplemented cultures. the incorporation of 3h-labeled deoxynucleosides into dna was higher in the presence of uri ... | 1975 | 126996 |
| the possible role of tightly bound adenine nucleotides in oxidative and photosynthetic phosphorylation. | the tightly bound nucleotides of the beff-heart mitochondrial atpase are released during cold inactivation followed by ammonium sulfate precipitation. during incubation at 0 degrees c the sedimentation coefficient (s20w) of the atpase first declines from 12.1s to 9s. prolonged incubation or precipitation with ammonium sulfate leads to dissociation of the 9s component into subunits with s20w of 3.5s. the 9s component still bears bound nucleotides which exchange more extensively and rapidly with a ... | 1975 | 127089 |
| pathway of succinate and propionate formation in bacteroides fragilis. | cell suspensions of bacteroides fragilis were allowed to ferment glucose and lactate labeled with (14)c in different positions. the fermentation products, propionate and acetate, were isolated, and the distribution of radioactivity was determined. an analysis of key enzymes of possible pathways was also made. the results of the labeling experiments showed that: (i) b. fragilis ferments glucose via the embden-meyerhof pathway; and (ii) there was a randomization of carbons 1, 2, and 6 of glucose d ... | 1978 | 148460 |
| effect of essential phospholipids on the properties of atpases of isolated rat liver plasma membranes of young and old animals. | "essential" phospholipids (epl), rich in dilinoleyl-phosphatidylcholine were given orally to young and 780-800 day-old rats. the double-labelled (14c/32p) dilinoleyl-phosphatidylcholine was incorporated in plasma membranes and the amounts incorporated into different organs investigated. old animals incorporated higher radioactivity than young. the 14c/32p ratio however decreased in comparison with the substance administered. the amount of (na+-k+)-atpase in rat liver plasma membranes of old anim ... | 1975 | 127894 |
| the influence of specific antibodies and cellular immunity in the induction of tolerance of chemotactic activity caused by bacteroides fragilis lipopolysaccharide. | exudate aspirated from wound chambers implanted subcutaneously on rabbits at different time intervals after local lipopolysaccharide (lps) injection, showed a peak of chemotactic mediator concentration in vitro about two hours before the peak of polymorphonuclear lekocytes accumulated in vivo was demonstrated. injection of lps locally into the wound chambers three days after the first injection of lps showed a reduced number of pmns accumulated in the exudate. antibodies to the lps preparation w ... | 1979 | 117673 |
| equine infectious respiratory disease. | during the past 20 years the equine population of great britain and ireland has increased with the result that the practising veterinary surgeon is more frequently called upon to advise on equine problems. a significant portion of this advice is concerned with the examination of horses showing signs of this advice is concerned with the examination of horses showing signs of respiratory disease. numerous pathogens, which include viruses, bacteria, parasites and moulds invade the respiratory tract ... | 1975 | 163516 |
| letter: susceptibility of bacteroides fragilis to spectinomycin. | | 1975 | 126984 |
| [a histochemical study of mesotheliomas of the pleura, induced by asbestos in rats]. | | 1976 | 132768 |
| effect of infrequent feeding and increased physical activity on cholesterol kinetics in the rat. | the authors studied the effect of chronic physical exercise (running in a rotating drum at 850 m/hour, 5 times a week for 16 weeks) on the size of the cholesterol body pools and on cholesterol kinetics in adult male wistar rats fed on a standard diet either ad libitum or 2 hours daily [33 weeks]. these data were obtained by mathematical analysis of the curve expressing the correlation of specific plasma cholesterol activity to time after a single dose of cholesterol-4-14c. chronic physical stres ... | 1978 | 149317 |
| [hemodynamic study of postural regulation in the dog treated or not treated with levomepromazine]. | analysis of hemodynamic parameters in untreated and treated dogs (levomepromazine 5 mg/kg i.v.) during supine and erect position showed, 1) that the regulation of cerebral blood flow remained in the anaesthetized (pentobarbital 25 mg/kg i.v.) dogs ; 2) that the sympathetic reaction induced different effects in various vascular regions ; 3) that levomepromazine induced an impairement of the mechanisms involved in the regulation of the encephalic irrigation. | 1976 | 134816 |