| the prevalence of salmonella enteritidis and other salmonella sp. among canadian registered commercial chicken broiler flocks. | a nation-wide survey was conducted to estimate the prevalence of salmonella enteritidis and other salmonellas among canadian commercial broiler flocks. environmental (litter and/or water) samples from 226 of 294 (76.9%) randomly selected flocks were contaminated with salmonellas. litter samples were more often contaminated with salmonellas than water samples (47.4 v. 12.3%). fifty different salmonella serovars were isolated. the most prevalent serovars were s. hadar, s. infantis, and s. schwarze ... | 1991 | 1879484 |
| human immune response to an iron-repressible outer membrane protein of bacteroides fragilis. | under conditions of iron starvation, bacteroides fragilis expresses various iron-repressible outer membrane proteins (iromps). a 44-kda protein appears to be one of the major outer membrane proteins (omps) in b. fragilis under iron stress and plays a role in heme uptake by this bacterium. to determine whether the 44-kda iromp of b. fragilis is expressed in vivo and whether this protein is immunogenic, we used western immunoblotting to examine serum samples from patients with an infection caused ... | 1991 | 1879923 |
| [influence of cefodizime on intestinal bacterial flora]. | effects of cefodizime (cdzm), a new injectable cephem antibiotic, on the intestinal bacterial flora were studied in tetra-contaminated mice and in pediatric patients. cdzm was intramuscularly administered at a dose of 100 mg/kg once a day for 5 consecutive days to mice contaminated with 4 different species of organisms: escherichia coli, enterococcus faecalis, bacteroides fragilis and bifidobacterium breve. for 3 species except e. faecalis, bacterial populations in feces were markedly reduced af ... | 1991 | 1880920 |
| meropenem: in-vitro activity and kinetics of activity against organisms of the bacteroides fragilis group. | meropenem was compared with imipenem and nine other antimicrobial agents, against 101 strains of the bacteroides fragilis group. meropenem was active against all strains tested, and its activity was similar to, and in many cases better than, that of imipenem. the activity of meropenem was similar to that of metronidazole, and greater than that of the other antimicrobial agents tested. the bactericidal activity of meropenem against b. fragilis was impressive, since the mbc to mic ratios were no g ... | 1991 | 1885418 |
| in vitro antibacterial activities of the fluoroquinolones pd 117596, pd 124816, and pd 127391. | three new aminopyrrolidine-substituted fluorocyclopropyl quinolones--pd 117596, pd 124816, and pd 127391--were tested for in vitro antibacterial activity against 349 bacterial strains, which are primarily clinical isolates. the minimum inhibitory concentrations (mic) in micrograms/ml required for greater than or equal to 90% of strains were 0.03-0.06 for staphylococci (26 strains); 0.06-0.25 for streptococcus pyogenes, s. agalactiae, s. pneumoniae, and enterococcus faecalis (80); less than or eq ... | 1991 | 1889177 |
| antimicrobial activity of e-1040, a novel thiadiazolyl cephalosporin compared with other parenteral cephems. | e-1040, a new parenteral fourth-generation cephalosporin, was tested against greater than 600 bacteremic pathogens and compared with cefotaxime, ceftazidime, and cefpirome. e-1040 activity against staphylococcus aureus was comparable (mic90, 8 micrograms/ml) to ceftazidime, but inferior to cefotaxime (mic90, 2 micrograms/ml) and cefpirome (mic90, 0.5 microgram/ml). beta-hemolytic streptococci and most gram-positive anaerobes were also susceptible to e-1040. some strains of coagulase-negative sta ... | 1991 | 1889181 |
| the comparative antimicrobial effect of calcium hydroxide. | the antimicrobial effectiveness of calcium hydroxide, camphorated paramonochlorophenol, and formocresol in root canals of extracted human teeth was compared. canals in single-rooted teeth were enlarged and inoculated with streptococcus mutans, actinomyces viscosus, and bacteroides gingivalis or bacteroides fragilis. after treatment with a test agent and sealing and incubation for 1 hour, the canal contents were analyzed for the number of viable test bacteria and compared with that of inoculated ... | 1991 | 1891227 |
| analysis of inducers of the e.coli lac repressor system in mammalian cells and whole animals. | although the inducible prokaryotic lac repressor system has been successfully adapted for control of gene expression in mammalian cells, little information is available on the pharmacokinetics of beta-galactoside inducers in mammalian cells for optimizing this system. these studies directly measure the cell uptake and clearance in cultured cells and animal tissue cells of lac inducers. in these cells, the beta-galactosides, isopropyl beta-d-thiogalactoside (iptg) and methyl beta-d-thiogalactosid ... | 1991 | 1891356 |
| association of antisense oligonucleotides with lipoproteins prolongs the plasma half-life and modifies the tissue distribution. | in order to direct antisense oligonucleotides to specific tissues or cell types in vivo, we are exploring the possibility to utilize lipoproteins as transport vehicles. a 16-mer oligonucleotide (odn) was derivatized at the 5' prime through a 32p phosphate spacer with cholesterol, yielding a 32p-labeled amphiphatic cholesteryl-oligonucleotide (cholodn). incubation of cholodn with low-density lipoprotein (ldl) for 2 hr at 37 degrees c resulted in the formation of a cholodn-ldl complex that migrate ... | 1991 | 1891360 |
| in vitro and in vivo activities of ljc10,627, a new carbapenem with stability to dehydropeptidase i. | the activity of ljc10,627 was compared with the activities of imipenem and other antibiotics. ljc10,627 was more active against most members of the family enterobacteriaceae, pseudomonas spp., and acinetobacter spp. but slightly less active than imipenem against staphylococci and streptococci. ljc10,627 showed stability to mouse dehydropeptidase i and was more effective in vivo than imipenem plus cilastatin against gram-negative bacterial infections and as effective against staphylococcal infect ... | 1991 | 1901698 |
| biochemical properties and purification of metallo-beta-lactamase from bacteroides fragilis. | the beta-lactamase from bacteroides fragilis gai-30144 hydrolyzed imipenem, oxyiminocephalosporins, cephamycins, and penicillins. enzyme activity was inhibited by edta. zinc completely reversed inactivation of the enzyme by edta. the molecular mass of purified enzyme was estimated to be 33,000 daltons. | 1991 | 1902649 |
| formation of glycoprotein degrading enzymes by bacteroides fragilis. | bacteroides fragilis ncdo 2217 produced a wide range of cell-associated hydrolytic enzymes (neuraminidase, alpha-fucosidase, alpha-n-acetylgalactosaminidase, beta-galactosidase, beta-n-acetylglucosaminidase) that could potentially degrade the carbohydrate moieties of mucin, a complex glycoprotein. the type of substrate used for growth markedly influenced their formation in batch cultures. synthesis of neuraminidase, alpha-fucosidase, alpha-n-acetylgalactosaminidase and to a lesser extent, beta-n ... | 1991 | 1903753 |
| inactivation of metronidazole by enterococcus faecalis. | the in-vitro inactivation of metronidazole by different clinical isolates of enterococcus faecalis was investigated by means of association experiments in which ent. faecalis strains and bacteroides fragilis group strains were cultured in the same liquid medium. all of the tested ent. faecalis strains (20 isolates) were able to protect the b. fragilis group strains against the killing effect of metronidazole at a concentration four or eight times higher than the normal mic. different strains of ... | 1991 | 1904851 |
| hydrophobic membrane thickness and lipid-protein interactions of the leucine transport system of lactococcus lactis. | the effect of the phospholipid acyl chain carbon number on the activity of the branched-chain amino acid transport system of lactococcus lactis has been investigated. major fatty acids identified in a total lipid extract of l. lactis membranes are palmitic acid (16:0), oleic acid (18:1) and the cyclopropane-ring containing lactobacillic acid (19 delta). l. lactis membrane vesicles were fused with liposomes prepared from equimolar mixtures of synthetic phosphatidylethanolamine (pe) and phosphatid ... | 1991 | 1905573 |
| nucleotide sequence of ermfu, a macrolide-lincosamide-streptogramin (mls) resistance gene encoding an rna methylase from the conjugal element of bacteroides fragilis v503. | | 1991 | 1905805 |
| inhibition of no3-, nh4+, and po4(3-) uptake in anabaena doliolum exposed to a petroleum oil. | the aqueous extract of assam crude inhibited the uptake of no3-, nh4+, and po4(3-) in anabaena doliolum and the response was essentially concentration dependent. inhibition was most severe for the uptake of nh4+ followed in decreasing order by po4(3-) and no3-. uptake of nutrients was competitively inhibited as in all the cases oil extract did not change vmax; however, apparent km was increased. the nature of oil components competing with nutrient ions is not certain at present. oil-induced inhi ... | 1991 | 1905997 |
| measurement of human cerebral monoamine oxidase type b (mao-b) activity with positron emission tomography (pet): a dose ranging study with the reversible inhibitor ro 19-6327. | eight normal subjects (3 females and 5 males) were studied using intravenous l-[11c] deprenyl and positron emission tomography. in a single blind study one subject received tracer alone, one subject received an oral pre-dose of 20 mg of l-deprenyl and 6 subjects received oral pre-doses of 10 to 50 mg of a novel reversible mao-b inhibitor (ro 19-6327). dynamic pet scans beginning 12 h after the oral dose were collected over 90 min and arterial blood was continuously sampled. data analysis was mod ... | 1991 | 1906004 |
| biological functions of the water-insoluble fraction of mouse seminal vesicle fluid. i. suppression of the blastogenic response of lymphocytes. | the effects of the water-insoluble fraction of mouse seminal vesicle fluid (wif-svf) on lymphocytes was investigated to clarify its role in reproductive immunity. wif-svf inhibited the blastogenic response of t-cells to concanavalin-a (con-a), but it did not inhibit the blastogenic response of b-cells to lipopolysaccharide (lps). pretreatment of splenocytes with wif-svf did not suppress the blastogenic response of splenocytes to con-a when treated cells were washed prior to culture. wif-svf did ... | 1991 | 1906049 |
| in vivo kinetics and characterization of ifn-gamma-producing cells during a thymus-independent immune response. | using immunohistochemical techniques, we studied ifn-gamma-producing cells (ifn-gamma-pc) in vivo during immune responses to thymus-independent type-2 (ti-2) ag. detection of ifn-gamma-pc in cryostat sections of spleen-tissue was performed with an enzyme labeled mab directed against ifn-gamma. after tnp-ficoll immunization, ifn-gamma-pc and tnp-specific antibody-forming cells (tnp-afc) displayed similar kinetics reaching a maximum number at day 5 to 7. the ifn-gamma-pc were localized in the same ... | 1991 | 1906499 |
| inhibitory effect of cyclosporine a on the activity of oral hypoglycemic agents in rats. | diabetic patients often have a kidney or pancreas allograft requiring cyclosporine a (csa) to prevent transplant rejection. these patients usually take p.o. hypoglycemic agents to control their diabetes. because of the reported adverse effects of csa on glucose metabolism as well as its potential use in type ii diabetics, we were interested in evaluating the in vivo effect of csa on the activity of p.o. hypoglycemic agents. we also wanted to determine if tolbutamide produced any adverse effects ... | 1991 | 1906541 |
| sds-page and immunological analysis of different axenic blastocystis hominis strains. | consistent major differences were detected by sds-page, western blotting and ouchterlony immunodiffusion in four axenic and microscopically indistinguishable strains of the anaerobic human parasite blastocystis hominis from different sources. it is concluded that at least two variants with different polypeptide patterns and antigens exist and the biological significance of these findings is discussed. | 1991 | 1906543 |
| antibiotic ge2270 a: a novel inhibitor of bacterial protein synthesis. i. isolation and characterization. | a novel antibiotic, ge2270 a, was isolated from the fermentation broth of a strain of planobispora rosea. the product was found to inhibit bacterial protein synthesis. structural characteristics showed similarities between ge2270 a and thiazolyl peptides such as micrococcin which is known to inhibit protein synthesis by acting directly on the ribosome. despite this similarity ge2270 a showed functional analogy to kirromycin-like antibiotics and pulvomycin, as its molecular target was found to be ... | 1991 | 1908853 |
| transmembrane diffusion of hydrophobic antimicrobial agents and cell surface hydrophobicity in bacteroides fragilis. | the transmembrane diffusion of hydrophobic antimicrobial agents, e.g. lincomycin and clindamycin, was examined in bacteroides fragilis which is sensitive to these agents. the results showed that these agents penetrate efficiently through the outer membrane. cell surface hydrophobicity measured by the partition assay between water and p-xylene revealed that the cell surface of b. fragilis is more hydrophobic than that of salmonella typhimurium or pseudomonas aeruginosa. furthermore, treatment wit ... | 1991 | 1909281 |
| in vitro antimicrobial activity of sparfloxacin (at-4140, ci-978, pd 131501) compared with numerous other quinolone compounds. | sparfloxacin (at-4140, ci-978, pd 131501) was tested against over 800 recent bacteremic strains and compared with ciprofloxacin and six other fluoroquinolones. the 90% minimum inhibitory concentration (mic90) ranges for the enterobacteriaceae species were (a) sparfloxacin, 0.03-1 microgram/ml and (b) ciprofloxacin, 0.015-0.25 microgram/ml. moraxella catarrhalis, haemophilus influenzae, and neisseria gonorrhoeae were very susceptible to sparfloxacin (mic90s, 0.004- less than or equal to 0.03 micr ... | 1991 | 1909615 |
| [presence of neuritic plaques and neurofibrillary changes in the cerebral cortex of an aged lemuride primate]. | some aged microcebus murinus brains (8 to 11-years old animals) displayed a dramatic atrophy particularly in the neocortex, hippocampus, basal ganglia, hypothalamus, brainstem and cerebellum, associated with a conspicuous increase in the size of the cerebral ventricles. these morphological changes were accompanied by certain histological profiles indicative of pathology. in the cortex, these histological changes consisted of (1) a large number of neuritic plaques formed by degenerated neurites s ... | 1991 | 1913260 |
| a study of the candidate virulence factors of bacteroides fragilis. | bacteroides fragilis strains were classified as virulent or avirulent on the basis of their clearance from the subcutaneous tissues of mice. to determine the factors which may contribute to the virulence of b. fragilis strains, we studied encapsulation, hydrophobicity, growth rate, serum sensitivity, agglutination with erythrocytes of different origin, and neuraminidase production. the strains of the virulent group displayed a higher growth rate in broth and a lower sensitivity to the bactericid ... | 1991 | 1919517 |
| anaerobic bacteremia: decreasing rate over a 15-year period. | at the mayo clinic, the number of cases of anaerobic bacteremia decreased 45% between 1974 and 1988. in addition, the percentage of blood cultures positive for anaerobes decreased significantly even though the total number of blood cultures performed increased. the number of anaerobic bacteremias per 100,000 patient-days also declined over the 15-year period. organisms of the bacteroides fragilis group ranked third in frequency with respect to other organisms that caused aerobic and anaerobic ba ... | 1991 | 1925283 |
| [beta-lactam/beta-lactamase inhibitor combinations for oral administration]. | beta-lactamase inhibitors are compounds which are able to bind many beta-lactamase and to inactivate them irreversibly ("suicide inactivators"). their intrinsic antimicrobial activity is weak. however, in combination with aminopenicillins they exhibit marked synergism both in vitro and in vivo against many beta-lactamase producing bacterial strains. at the achievable serum and tissue concentrations after oral administration, various aminopenicillin/beta-lactamase inhibitor combinations are activ ... | 1991 | 1925470 |
| susceptibilities of 394 bacteroides fragilis, non-b. fragilis group bacteroides species, and fusobacterium species to newer antimicrobial agents. | the susceptibilities of 374 selected beta-lactamase-producing gram-negative anaerobes (including 22 cefoxitin-resistant strains and 36 strains refractory to the enhancing effect of beta-lactamase inhibitors) and 20 beta-lactamase-negative strains were tested by agar dilution against selected new agents. the organisms included 217 bacteroides fragilis group strains, 137 non-b. fragilis group bacteroides spp., and 40 fusobacteria. all strains were susceptible to piperacillin-tazobactam, imipenem, ... | 1991 | 1929264 |
| effect of beta-lactamase inhibitors on the activities of various beta-lactam agents against anaerobic bacteria. | the in vitro activities of several new beta-lactam-beta-lactamase inhibitor combinations (piperacillin plus tazobactam, ceftizoxime and cefonicid with sulbactam and clavulanic acid, and ampicillin plus 8 micrograms of sulbactam per ml) were tested with anaerobic bacteria and compared with known beta-lactam-beta-lactamase inhibitor combinations and other potent antianaerobe agents. all the combinations tested (except for the cefonicid-inhibitor combinations) were active against almost all strains ... | 1991 | 1929265 |
| intravascular plastic catheters. how they potentiate tumor necrosis factor release and exacerbate complications associated with sepsis. | we tested the hypothesis that long-term intravascular cannulation exacerbates the harmful effects of an infectious challenge. four groups of rats were initially studied: rats without intravascular catheters or infection (group 1), rats without catheters with a polymicrobial infection (group 2), rats with catheters but no infection (group 3), and rats with catheters and infection (group 4). infected animals had an increased mortality and generated a significantly increased tumor necrosis factor r ... | 1991 | 1929838 |
| insulin dependent diabetes mellitus hypothesis of autoimmunity. | | 1991 | 1932509 |
| purification and cdna sequencing of an oleate-selective acyl-acp:sn-glycerol-3-phosphate acyltransferase from pea chloroplasts. | the soluble acyl-acp:sn-glycerol-3-phosphate acyltransferase from chloroplasts of chilling-sensitive and -resistant plants differ in their fatty acid selectivity. enzymes from resistant plants discriminate against non-fluid palmitic acid and select oleic acid whereas the acyltransferase from sensitive plants accepts both fatty acids. to use this difference for improving plant chilling resistance by biotechnology the gene for an oleate-selective enzyme is required. therefore, the oleate-selective ... | 1991 | 1932680 |
| identification of novel protein tyrosine phosphatases of hematopoietic cells by polymerase chain reaction amplification. | polymerase chain reaction (pcr) conditions were used to amplify cdnas that encode putative protein tyrosine phosphatases (ptps) from a murine interleukin-3-dependent myeloid cell line. primers for the reactions were based on conserved sequences of the catalytic domain that are shared among all known ptps. sequencing of 100 pcr-amplified cdna clones identified seven different cdna sequences. two of these sequences were identical to the murine ptp genes ly5/cd45/lca and lrp/r-ptp-alpha. two of the ... | 1991 | 1932742 |
| the gene for the alpha 4 subunit of the vla-4 integrin maps to chromosome 2q31-32. | the vla-4 integrin (cd49d/cd29), initially discovered on lymphoid cells, is actually known to be highly expressed on t cells, b cells, monocytes, and derived cell lines. unlike other vla integrins, mainly involved in cell-matrix adhesive interactions, vla-4 has also been implicated in several cellular interactions. based on the published alpha 4 cdna sequence, a 1,142-bp alpha 4 cdna fragment was amplified using the polymerase chain reaction. this fragment was used to isolate three overlapping g ... | 1991 | 1932750 |
| purification of a gsh-affinity binding protein from bacteroides fragilis devoid of glutathione transferase activity. | an affinity binding protein from the cytosolic fraction of bacteroides fragilis was purified by using epoxy activated-sepharose 6b resin immobilized with gsh or with hexyl-gsh. this protein showed a subunit molecular mass (22 kda) similar to that of glutathione transferase purified from proteus mirabilis (22.5 kda). however, the affinity binding protein of bacteroides fragilis, unlike the gsh-affinity binding protein of proteus mirabilis, was devoid of the capacity to conjugate gsh to the most c ... | 1991 | 1936932 |
| the use of bacteriophages of bacteroides fragilis as indicators of the efficiency of virucidal products. | the potential use of bacteriophage b40-8 of bacteroides fragilis for the evaluation of the virucidal activity of antiseptics or disinfectants was investigated. the antiviral activity of two antiseptics and two disinfectants was evaluated according to a standard guideline. the effect of the virucidal agents was assessed on (i) viruses usually spread by direct contact with surfaces with contaminated secretions, i.e. herpes virus 1 and 2, and vaccinia virus, and (ii) viruses transmitted by the feca ... | 1991 | 1936937 |
| detection of bacteroides infection by counter immunoelectrophoresis test. | the counterimmunoelectrophoresis (cie) test using sonicated antigens of bacteroides fragilis nctc 2553 and a b. asaccharolyticus strain, standardised in the laboratory yielded a negative result in the 50 normal sera tested, while it was positive in 24 of 34 (71%) patients with infection due to black pigmented bacteroides and in 10 of 15 (67%) with b. fragilis infection. the microagglutination test (mat) done in parallel showed a positivity of only 44 and 40 per cent respectively. the cie test do ... | 1991 | 1937595 |
| ribosomal binding and accumulation of rokitamycin in bacteroides fragilis. | | 1991 | 1938610 |
| evaluation of the e test for susceptibility testing of anaerobic bacteria. | the susceptibilities of 105 clinical isolates of anaerobic bacteria were determined by a new method, the e test (ab biodisk, solna, sweden), and were compared with the mics for these organisms obtained by the reference agar dilution method by using supplemented brucella and wilkins-chalgren agars. the e test is a plastic strip with a predefined antibiotic gradient immobilized on one side and a mic interpretive scale printed on the other side. strips with cefoxitin, cefotaxime, imipenem, penicill ... | 1991 | 1939571 |
| comparison of the activity of imipenem and beta-lactams combined with sulbactam and clavulanic acid in beta-lactamase-producing strains of bacteroides fragilis. | we compared the "in vitro" activity of imipenem with 14 beta-lactams, both alone and in combination with clavulanic acid, and sulbactam against 110 beta-lactamase-producing strains of bacteroides fragilis. the following antibiotics were tested: amoxycillin, penicillin, mezlocillin, piperacillin, cephalothin, cephazolin, cefamandole, cefmetazole, cefonicid, cefoxitin, cefotaxime, ceftazidime, ceftizoxime, and ceftriaxone. in all cases, except those of cefoxitin and cefmetazole, these combinations ... | 1991 | 1940333 |
| [venous thrombosis in gastroenterology]. | venous thrombosis involving the digestive tract affects the suprahepatic veins and the terminal part of the inferior vena cava, the portal vein and its roots. the etiology and diagnosis of this condition have made considerable progress. a thrombogenic disease can now be recognized in 90% of cases of involvement of the suprahepatic veins, and 75% of portal involvements. the most frequent causes are primary myeloproliferative syndromes, paroxysmal nocturnal hemoglobinuria, hereditary deficiency in ... | 1991 | 1940649 |
| high propionic acid fermentations and mineral accumulation in the cecum of rats adapted to different levels of inulin. | the digestive and metabolic effects of inulin (from chicory) were studied in rats adapted to semipurified diets containing 0, 5, 10 or 20% inulin (wt/wt). moderate levels of inulin (5-10%) did not significantly affect food intake or body weight gain. dietary inulin resulted in considerably greater cecal fermentation and a significantly greater intraluminal concentration of propionate (peaking at 58.4 mmol/l). a lower concentration of acetate (42.6 mmol/l) was observed in rats fed 20% inulin. lac ... | 1991 | 1941180 |
| ceftriaxone (rocephin) in abdominal trauma. | a prospective study was undertaken to evaluate the use of ceftriaxone in patients with abdominal trauma admitted to our hospital over a period of 6 months. because of the large trauma load and an unacceptable waiting period before surgery combined with the fact that many patients on 6-hourly antibiotic regimes often did not receive their second and third doses, it was decided to use ceftriaxone because of its long half-life with maintenance of fluid and tissue concentrations for 24-48 hours. bec ... | 1991 | 1942169 |
| [trophic and regulatory relations between intestinal microflora and the macro-organism (on the pathogenesis of irritable bowel syndrome)]. | | 1991 | 1942966 |
| adenomatous hyperplasia of the bile duct epithelium of the canine liver, caused by bacterial infection. | morphologic changes of the intrahepatic bile ducts after induction of bile stasis and bacterial infection of the biliary tract in two lobes of the liver in mongrel dogs were studied to examine the pathophysiology of hepatolithiasis. three groups of dogs were prepared by cannulation of the bile duct branch draining the left lateral lobes of the liver and were treated as follows: in group 1 the cannula was clamped after injection of 10(7) escherichia coli (aerobic bacteria) and 10(7) bacteroides f ... | 1991 | 1947778 |
| [postcoital uterine microbe colonization and endometritis in the mare]. | in the mare, natural breeding is associated with bacterial contamination of the reproductive tract. the purpose of this study was to examine postcoital bacterial contamination and the resulting inflammatory response of the uterus. uterine swabs for bacteriological and cytological examination were obtained from 80 mares. each mare was sampled once between 4 and 69 hours postbreeding. in mares which did not conceive, sampling was repeated at the following estrus. the findings were compared with th ... | 1991 | 1948985 |
| ultrastructural lesions of enterotoxigenic bacteroides fragilis in rabbits. | | 1991 | 1949512 |
| [the austrian vaccination plan]. | in march 1991 the supreme board of health issued new recommendations for immunization of children which are basically similar to those issued in 1989, but were partially reformulated. again, bcg vaccination is not generally recommended and should be given only to individuals at high risk of contracting the disease. it is therefore not listed any more in the general recommendations (a) but only mentioned under special vaccinations (b). special indications for bcg vaccination were clearly reformul ... | 1991 | 1949818 |
| major salivary gland lymphoepithelial lesions and the acquired immunodeficiency syndrome. | presently, there is no consensus regarding the most appropriate diagnostic and therapeutic approach to patients with human immunodeficiency virus (hiv)-associated lymphoepithelial lesions of the major salivary glands. a retrospective review of 60 consecutive patients with lymphoepithelial lesions is presented. thirty-eight cases were associated with hiv infection. lesions associated with hiv infection were usually bilateral, multiple, cystic, and associated with lymphadenopathy. in contrast, in ... | 1991 | 1951883 |
| antiseptic effectiveness with fibroblast preservation. | the efficacy of topical antiseptic therapy for wounds and skin ulcers has been shown to be at the expense of fibroblast and leukocyte function and, in general, wound healing. specifically, continued fibroblast function after exposure to antiseptics has been correlated to the concentration of the antiseptic. at concentrations that preserve fibroblast function, 0.005% sodium hypochlorite, 0.001% providone-iodine, 0.0025% acetic acid, and 0.003% hydrogen peroxide were tested for their effectiveness ... | 1991 | 1952753 |
| comparison of the inoculum effect of cefoxitin and other cephalosporins and of beta-lactamase inhibitors and their penicillin-derived components on the bacteroides fragilis group. | we compared the inoculum effects for 109 recent clinical isolates of the bacteroides fragilis group of cefoxitin, cefotetan, ceftizoxime, ceftriaxone, and three beta-lactamase inhibitors (clavulanic acid, sulbactam, and tazobactam) and their penicillin-derived components. bactericidal activity was assayed and morphologic changes were monitored for selected strains exhibiting a large inoculum effect. ceftizoxime demonstrated the largest inoculum effect, followed by cefotetan and ceftriaxone. the ... | 1991 | 1952860 |
| [bacteremia caused by bacteroides fragilis originating in the urinary bladder]. | | 1991 | 1954271 |
| escherichia coli chromosomal mutations that permit direct cloning of the bacteroides fragilis metallo-beta-lactamase gene, ccra. | the class b, metallo-beta-lactamase genes ccra (carbapenem- and cephamycin resistance) from three bacteroides fragilis isolates--qmcn3, qmcn4, and tal3636--were cloned and expressed in escherichia coli. cloning of the genes, by selecting for ampicillin resistance, was facilitated by two classes of escherichia coli chromosomal mutations which resulted in at least a 5-10-fold increase in metallo-beta-lactamase enzymatic activity. the observed increase in enzymatic activity is due to either increas ... | 1991 | 1956298 |
| virulence factors in bacteroides fragilis group. | attempts were made to study the virulence factors in some strains of b. fragilis group in the rat model. subcutaneous wound abscesses could be produced by 10(9) cfu/ml of live cells of all the five species of b. fragilis group tested. for determination of virulence factor cellular components (capsular polysaccharide and lipopolysaccharide) of b. fragilis were separated using gel filtration technique and injected in rats. abscesses could be produced only by capsular polysaccharide fraction sugges ... | 1991 | 1959952 |
| evaluation of the rapid id 32a system for the identification of bacteroides fragilis and related organisms. | this study evaluated the ability of a rapid identification system for anaerobic bacteria, atb 32a, now renamed rapid id 32a (api-biomérieux uk ltd., basingstoke), to identify accurately 74 strains of the 'b. fragilis group'. atb 32a identified correctly 78.4% of strains to species level, without supplemental tests. the percentage of strains identified to species level rose to 94.6% when a supplementary test (advised by biomérieux) for catalase production was used to differentiate between bactero ... | 1991 | 1960112 |
| comparative efficacy of cefoperazone, cefoperazone plus sulbactam, ciprofloxacin, clindamycin, metronidazole, and penicillin g against anaerobic bacteria in an animal model. | treatment efficacy of various antimicrobial regimens against anaerobes was studied in semipermeable chambers simulating a closed-space, locally neutropenic infection site in rabbits. bacteroides fragilis, bacteroides melaninogenicus, clostridium perfringens, and peptostreptococcus anaerobius were inoculated (at a mean of 5.3 log10 cfu/ml in prereduced pooled rabbit serum) into the chambers (one isolate per chamber) in triplicate. antimicrobial therapy consisted of cefoperazone, cefoperazone plus ... | 1990 | 1967626 |
| [development and preliminary characterization of monoclonal antibodies to 987p adhesin antigen of e. coli]. | a panel of 11 monoclonal antibodies (mabs) to 987p adhesin antigen of e. coli were developed and partially characterized. they only reacted with e. coli strains bearing 987p adhesin but neither with other e. coli (k88+, k99+ and f41+) strains nor other species in family of enterobacteriaceae in if or elisa. the amount of 987p+ bacteria which could be detected by the hrpo-conjugated mab epn3 was as small as 2 x 10(3) cells/ml, and the detected rate of fecal or intestinal samples from piglets with ... | 1990 | 1971468 |
| [anaerobic gram-negative bacilli]. | | 1990 | 1976009 |
| the role of alpha- and beta-adrenoceptor subtypes in mediating the effects of catecholamines on fasting glucose and insulin concentrations in the rat. | 1. the role of alpha- and beta-adrenoceptor subtypes in the regulation of plasma glucose and immunoreactive insulin (iri) levels has been investigated in normal conscious fasted rats by employing selective agonists and antagonists. 2. adrenaline (0.2 mg kg-1)-induced hyperglycaemia was abolished by the selective alpha 2-adrenoceptor antagonist idazoxan (1.0 mg kg-1), unaltered by non-selective beta-adrenoceptor blockade (propranolol, 1.0 mg kg-1) and potentiated by the selective alpha 1-adrenoce ... | 1990 | 1976400 |
| the viability of microorganisms in preservation solutions. | in 1988 the university of wisconsin solution was introduced into clinical transplantation. this solution is unique in that it contains no glucose but rather raffinose, lactobionate, and hydroxyethyl starch. in addition, it contains two antibiotics, penicillin and bactrim. prior studies have shown that other preservation solutions allow the transmission of bacterial contamination from organ donor to recipient. however, there are no data on whether uw solution, with its unique composition and exte ... | 1991 | 1987693 |
| aerobic and anaerobic microbiologic factors and recovery of beta-lactamase producing bacteria from obstetric and gynecologic infection. | specimens obtained from 736 patients with obstetric and gynecologic infections were studied for aerobic and anaerobic bacteria. bacterial growth was present in 714 specimens. these included 53 specimens of infected fallopian tubes, 470 of infected endometrium, 94 of infected amniotic fluid, 57 of aspirates of cul-de-sacs in instances of pelvic inflammatory disease, 14 labial and vaginal abscesses and 26 of bartholyn's cyst abscess. a total of 2,052 isolates (2.9 per specimen), 1,139 anaerobes (1 ... | 1991 | 1989117 |
| bacterial killing in vitro by abscess-derived neutrophils. | in the absence of antimicrobial therapy, bacteria such as bacteriodes fragilis, escherichia coli and proteus mirabilis may persist within an intra-abdominal abscess in the presence of large numbers of neutrophils which, under optimal conditions in vitro, can readily phagocytose and kill the same bacterial strains. neutrophils taken from abscesses induced by gram-negative bacteria such as those above contain viable organisms. on incubation in vitro in the presence of serum, these neutrophils kill ... | 1991 | 1990143 |
| phospholipase c activity in microorganisms associated with reproductive tract infection. | phospholipase c (lecithinase or phosphatidylcholine phosphorylase) catalyzes the hydrolysis of lecithin into phosphorylcholine and 1,2-diglyceride. bacterial production of phospholipase c may damage reproductive tract tissues by both direct and indirect mechanisms. use of the synthetic substrate p-nitrophenylphosphorylcholine phospholipase c activity was determined in 204 isolates representative of those found in female genital tract. multiple aerobic (28%) and anaerobic (28%) reproductive tract ... | 1991 | 1992722 |
| transient and distant infections alter later intraperitoneal abscess formation. | transient nosocomial infections, such as line sepsis and pneumonia, are common in today's critical care patient population. although generally well treated, the effect of these transient antigen exposures on the immune system is unclear. we have previously shown that prior intraperitoneal inoculation with live bacteria leads to increased numbers of intraperitoneal abscesses. data presented here demonstrate in a murine model that two immunizations with live escherichia coli, bacteroides fragilis, ... | 1991 | 1992993 |
| multivariate analyses of cellular fatty acids in bacteroides, prevotella, porphyromonas, wolinella, and campylobacter spp. | the genera bacteroides, wolinella, and campylobacter contain several similar species that require taxonomic revision. fatty acid profiles of whole bacterial cells have proven useful for taxonomy. in this study, cellular fatty acids from bacteroides, prevotella, porphyromonas, wolinella, and campylobacter spp. were identified and quantitated by gas chromatography and gas chromatography-mass spectrometry, and the data were subjected to principal component analyses. bacteroides fragilis, the type s ... | 1991 | 1993755 |
| preexposure of the peritoneum to live bacteria increases later mixed intraabdominal abscess formation and delays mortality. | intraabdominal infections are a major source of morbidity and mortality for the trauma and postoperative patient. transient peritoneal contamination with bacteria after either intentional or unintentional violation of the gut are common. the effect of this intermittent antigen exposure upon later formation of intraabdominal abscesses is unclear. previous experiments by others have demonstrated that repeated exposure to bacteroides fragilis capsular polysaccharide can induce a t lymphocyte-mediat ... | 1991 | 1995742 |
| the peritoneal environment during infection. the effect of monomicrobial and polymicrobial bacteria on po2 and ph. | intraperitoneal (ip) abscesses frequently are composed of aerobes and anaerobes, and, in experimental models, a particulate adjuvant. the environmental changes effected by these components, either singularly or in combination, have not been well defined. the ip po2, ph, and recoverable bacteria from the peritoneum of rats were quantified over 6 hours during simple aerobic and anaerobic infections and during mixed peritonitis with and without a sterile feces-barium sulfate adjuvant (sfa). fourtee ... | 1991 | 1998406 |
| the effect of antimicrobial therapy on mixed infections with bacteroides species. is eradication of the anaerobes important? | antimicrobial agents were used alone or in combinations in order to explore their effect on mixed aerobic-anaerobic infections. subcutaneous abscesses were induced in mice by single and mixed infections of bacteroides fragilis, bacteroides melaninogenicus, staphylococcus aureus, streptococcus pyogenes, streptococcus faecalis, escherichia coli, klebsiella pneumoniae and pseudomonas aeruginosa. the infected animals were treated for 5 days with spiramycin, gentamicin or metronidazole alone, or metr ... | 1991 | 2002230 |
| microbiological study of hiv-related periodontitis. | the subgingival microbiota in 14 persons with hiv-periodontitis was examined. subgingival plaque samples were collected with paper points, transported in vmga iii, and plated on anaerobic enriched brucella blood agar and various selective media. hiv-periodontitis sites revealed actinobacillus actinomycetemcomitans, wolinella recta, peptostreptococcus micros, and bacteroides intermedius, each averaging 7% to 16% of the cultivable subgingival flora in positive patients. high levels of spirochetes ... | 1991 | 2002434 |
| anaerobic osteomyelitis. a new experimental rabbit model. | experimental studies of osteomyelitis have been hampered by methodologic problems. for inducing experimental anaerobic osteomyelitis, the medullary cavity of the proximal tibial metaphysis of five new zealand white rabbits was excavated and filled with a polyvinyl alcohol sponge. on the right side, 1 ml of a suspension containing bacteroides fragilis (10(7) colony-forming units/ml) was injected, while on the left side, ringer's solution was used as a control substance. within five weeks, all ani ... | 1991 | 2009670 |
| antimicrobial effects of the combination of ceftibuten and an orally absorbed penem sch 29482. | ceftibuten is a new beta-lactamase-stable 3-aminothiazolyl cephalosporin that lacks activity against staphylococci and group-b streptococci. we determined the effect of the combination of ceftibuten with sch 29482, an orally absorbed penem. the combination of the two agents was additive for 25% or indifferent for 57% of the gram-positive species, haemophilus, and moraxella tested with a mean fractional inhibitory concentration (fic) index of 0.75. the combination of ceftibuten and sch 29482 was ... | 1991 | 2013213 |
| antimicrobial activity of intravenous quinolones on the intestinal microflora in dogs. | the antimicrobial activity of intravenously given quinolones on the intestinal microflora was unknown and therefore studied in dogs with a surgically isolated loop of the jejunum. ciprofloxacin, enoxacin and norfloxacin were actively excreted by the intestinal mucosa and achieved therapeutic levels within the lumen of this isolated jejunal loop. also the total counts of enterococci and escherichia coli decreased in this loop of the jejunum as well as in the stool. all three quinolones, when give ... | 1991 | 2013243 |
| epidemiology, antimicrobial susceptibility, pathogenicity, and significance of bacteroides fragilis group organisms isolated at los angeles county-university of southern california medical center. | the epidemiology of species of the bacteroides fragilis groups isolated at los angeles county-university of southern california medical center was examined. in addition, frequency of resistance to six beta-lactam antibiotics (cefmetazole, cefotetan, ceftizoxime, imipenem, penicillin, and cefoxitin) and to clindamycin, chloramphenicol, and metronidazole was determined for each species. while b. fragilis was most commonly isolated, the other species of the b. fragilis group accounted for half of t ... | 1991 | 2017610 |
| resistance of anaerobic bacteria to antimicrobial agents. | | 1991 | 2017623 |
| foreign-body-associated experimental osteomyelitis induced with bacteroides fragilis and staphylococcus epidermidis in rabbits. | bacteroides fragilis and staphylococcus epidermidis, alone and in combination, were used to induce foreign-body-associated osteomyelitis in a rabbit model. in this model, a catheter, used as a foreign body, was implanted into the medullary cavity of the tibia. only two of five animals infected with s. epidermidis alone developed culture-positive osteomyelitis, whereas all three animals infected with b. fragilis alone developed osteomyelitis. all six animals infected with both microorganisms deve ... | 1991 | 2019061 |
| bfai, a new maei isoschizomer from bacteroides fragilis, recognizes the sequence 5' c decreases tag 3'. | | 1991 | 2020550 |
| cefmetazole sodium: pharmacology, pharmacokinetics, and clinical trials. | cefmetazole sodium is a semisynthetic cephamycin antibiotic. it has a broad spectrum of activity comparable to that of the second-generation cephalosporins, covering gram-positive, gram-negative, and anaerobic bacteria. unlike the second-generation cephalosporins, cephamycins such as cefmetazole are usually active against bacteroides fragilis. cefmetazole is also active against beta-lactamase-producing organisms that are resistant to first-generation cephalosporins or penicillins. the pharmacoki ... | 1991 | 2020609 |
| microbiological studies of decubitus ulcers in children. | specimens from 58 children with decubitus ulcers were cultured for aerobic and anaerobic bacteria. aerobic bacteria only were present in 29 (50%) ulcers, anaerobic bacteria only were recovered in 5 (9%), and mixed aerobic and anaerobic flora were present in 24 (41%). a total of 132 isolates (79 aerobes, 53 anaerobes) were recovered, an average of 2.3 isolates per specimen (1.4 aerobes, 0.9 anaerobes). the smallest number of isolates was recovered in ulcers of the skull (1.7 per site), and the hi ... | 1991 | 2023086 |
| role of newer antimicrobial agents in the treatment of mixed aerobic and anaerobic infections. | mixed infections with aerobic and anaerobic bacteria are being recognized with increasing frequency in clinical practice. several concepts regarding such infections are clinically significant for the physician. these include the presence and significance of species in the bacteroides fragilis group at clinical sites of infection, the facilitation of b. fragilis virulence by beta-lactamase producing aerobic bacteria and the role of enterococci in such infections. in response to the need for new f ... | 1991 | 2024228 |
| rapid differentiation of the species of the genus bacteroides sensu stricto by capillary gas chromatography of cellular carbohydrates. | whole-cell hydrolysates of bacteroides fragilis, the type species of the genus bacteroides castellani and chalmers 1919, and the genetical closely related species b. vulgatus, b. ovatus, b. eggerthii, b. distasonis, b. uniformis, b. thetaiotaomicron, b. stercoris, b. merdae, and b. caccae were used to determine characteristic carbohydrate patterns by capillary gas chromatography. on the basis of the chemical derivatization of the carbohydrates seven characteristic peaks for peracetylated aldonon ... | 1991 | 2030096 |
| temafloxacin: in vitro comparison with five other antibacterial agents. | the in vitro activity of the new fluorinated quinolone temafloxacin was compared with the activities of ciprofloxacin, fleroxacin, ofloxacin, ceftazidime and tobramycin. a total of 662 recent clinical isolates were included in the study, representing a variety of gram-negative and gram-positive bacteria. an agar dilution method was employed for the determination of minimal inhibitory concentrations (mics). ciprofloxacin showed the highest potency against the enterobacteriaceae, 90% of the isolat ... | 1991 | 2032475 |
| [purification and immunological behavior of beta-lactamase from bacteroides fragilis]. | the beta-lactamase crude extract of bacteroides fragilis 55 was chromatographed with deae-sepharose cl-6b and sephadex g-100. the partial purified enzyme proteins was further purified by cutting the band on page in which the beta-lactamase was distinguishable from other proteins by our method of fluorescent staining. using purified preparations to be mixed with liposome-cps-k, prepared specific antisera against the purified beta-lactamase. serological reactions were carried out by igg-elisa toge ... | 1991 | 2035276 |
| immunochemical characterization of two surface polysaccharides of bacteroides fragilis. | immunochemical analysis of the capsular polysaccharide from bacteroides fragilis nctc 9343 revealed a novel structure composed of two distinct polysaccharides. immunoelectrophoresis of an extract of purified surface polysaccharide from fermenter-grown organisms showed a complex precipitin profile with varying anodal mobility. deae-sephacel anion-exchange chromatography of the polysaccharide extract failed to separate the majority of this aggregate. disaggregation of this complex was accomplished ... | 1991 | 2037368 |
| anaerobic infections. the basics for primary care physicians. | anaerobic bacteria constitute a major portion of the normal human microflora, and some of them can cause disease in contiguous body parts, especially if there is a mucosal break. most anaerobic infections are polymicrobial. because anaerobes are difficult to culture, diagnosis is often made on the basis of clinical clues. thus, knowledge of the common sites, predisposing conditions, and other representative features of anaerobic infections is critical. for anaerobic infections above the diaphrag ... | 1991 | 2038594 |
| in vitro and in vivo antibacterial activities of e-4497, a new 3-amine-3-methyl-azetidinyl tricyclic fluoroquinolone. | the in vitro and in vivo antibacterial activities of a new tricyclic fluoroquinolone, e-4497 [s(-)-9-fluoro-3-methyl-10-(3-amine-3-methyl-azetidin-1-yl)-7-oxo- 2,3-dihydro- 7h-pyrido-(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid], were evaluated in comparison with those of dr-3355 [s-(-)-ofloxacin], norfloxacin, and ciprofloxacin. e-4497 was more potent than norfloxacin and as potent as or more potent than dr-3355 and ciprofloxacin against staphylococcus spp., streptococcus spp., and enterococcus ... | 1991 | 2039195 |
| in vitro activity of sparfloxacin. | sparfloxacin, a new fluoroquinolone, inhibited the majority of members of the family enterobacteriaceae at less than or equal to 1 microgram/ml. it was less active than ciprofloxacin but more active than ofloxacin. against pseudomonas aeruginosa, it was less active than ciprofloxacin but twofold more active than ofloxacin. it inhibited staphylococcus aureus and most streptococcus pneumoniae and streptococcus pyogenes isolates at 0.25 micrograms/ml, whereas ciprofloxacin and ofloxacin inhibited t ... | 1991 | 2039209 |
| efficacy and safety of recombinant human erythropoietin to prevent the anaemias of prematurity. european randomized multicenter trial. | | 1991 | 2040194 |
| media- and method-dependent variation in mic values of ceftizoxime for clinical isolates of the bacteroides fragilis group. | although ceftizoxime has been used effectively in several clinical trials for infections involving anaerobic bacteria, reports of its in-vitro activity against anaerobes are contradictory and confusing. in an effort to clarify the discrepant reports, we tested 90 strains of bacteroides fragilis group organisms from patients with perforated or gangrenous appendicitis using eight different susceptibility testing procedures. the minimal inhibitory concentration values were dependent on the techniqu ... | 1991 | 2040893 |
| [antibacterial activity of ciprofloxacin against fresh clinical isolates from superficial suppurative foci]. | the minimum inhibitory concentrations (mics) of 5 drugs (ciprofloxacin (cpfx), and 4 drugs used as standard) were determined to investigate antibacterial potencies of cpfx against bacterial strains isolated in 1989 from superficial suppurative foci. the clinical isolates tested included 375 strains from 11 aerobic bacterial species, and 50 strains from 2 anerobic bacterial genera (group) for a total of 425 isolates. interpreting mic level distributions of these drugs as the expression of antibac ... | 1991 | 2041153 |
| effects of beta-lactamase-mediated antimicrobial resistance: the role of beta-lactamase inhibitors. | production of beta-lactamase is the most common mechanism of bacterial resistance to beta-lactam antibiotics. virtually all bacteria have the capability of synthesizing the enzyme. microorganisms may already possess the native genetic information necessary for beta-lactamase production (i.e., chromosomal), or may acquire the capacity by transfer of dna from another organism (i.e., plasmid-mediated). the level of beta-lactamase production may be stable and noninducible (constitutive enzyme produc ... | 1991 | 2041831 |
| newer beta-lactam agents and the bacteroides fragilis group. | a continuing nationwide susceptibility survey of the bacteroides fragilis group, begun in 1981, is being conducted at the new england medical center. review of susceptibility testing in years 1986 through 1988 is reported here. totals of 557 strains in 1986, 506 in 1987, and 534 in 1988 were obtained from seven centers in the united states. the most active beta-lactam drugs were beta-lactamase-inhibitor combinations ticarcillin-clavulanic acid, ampicillin-sulbactam, cefoperazone-sulbactam and th ... | 1991 | 2041832 |
| antimicrobial therapy of anaerobic infections, 1991. | most anaerobic infections are polymicrobial and must be treated with agents active against a variety of both aerobic and anaerobic bacteria. antimicrobial therapy is used both to contain infections and to treat those that have not been contained (bacteremia). bacterial resistance, especially to penicillins and tetracyclines, but also to newer agents of other classes, continues to increase and often requires treatment with more than one drug. combination therapy is also frequently necessary in se ... | 1991 | 2041835 |
| paradoxical sleep increases predict successful learning in a complex operant task. | the sleep of 16 sprague-dawley rats was continuously monitored both before and during task acquisition. eight rats were exposed in turn to autoshaping, 10-response fixed-ratio (fr 10), and sequential operant (so) tasks. they all learned the autoshaping and fr 10 tasks with equal ease. however, 4 rats were unable to solve the so task and were labeled as slow learning (sl). the other 4 rats did learn the task and were labeled as fast learning (fl). fl rats exhibited more paradoxical sleep than eit ... | 1991 | 2043274 |
| assessment of abdominal fat deposition in female cynomolgus monkeys. | computed tomography (ct) was used to assess abdominal fat distribution in adult, female cynomolgus macaques (macaca fascicularis). the technique used was similar to that applied in human beings and allowed intra-abdominal, subcutaneous and total abdominal fat to be quantitated in 1 cm thick sections. correlations between single scans and the average of scans at several levels ranged from r = 0.96 to r = 1.00, indicating that a single scan is representative of abdominal fat distribution. signific ... | 1991 | 2045214 |
| comparative efficacies of ticarcillin, ticarcillin/clavulanic acid, piperacillin and cefoxitin against polymicrobial infections in mice caused by escherichia coli and bacteroides fragilis. | a model of localised abscess formation was used to establish mixed infections caused by escherichia coli and bacteroides fragilis. the beta-lactamase producing, ticarcillin-resistant strains e. coli e96 and b. fragilis vpi 8708 were used to produce one infection, and in another infection, a beta-lactamase hyperproducing strain e. coli 41548 was combined with a ticarcillin-susceptible strain, b. fragilis b3. treatment, at doses producing clinically achievable concentrations in mouse serum, began ... | 1991 | 2050417 |
| in-vitro activity of four penicillin/beta-lactamase inhibitor combinations against cefoxitin-susceptible and cefoxitin-resistant bacteroides fragilis isolates. | | 1991 | 2055814 |
| vaginal bacteroides species are associated with an increased rate of preterm delivery among women in preterm labor. | the relationship of high concentrations of vaginal microorganisms with an increased rate of preterm delivery (less than or equal to 34 weeks) among women in preterm labor was evaluated. quantitative vaginal cultures were obtained from 211 women in preterm labor between gestational ages of 22 and 34 completed weeks. preterm delivery occurred in 139 (66%). the rate of preterm delivery was determined by cox proportional hazards models. women with greater than 10(7) cfu/ml of vaginal fluid of facult ... | 1991 | 2056221 |
| [acute anaerobic paraproctitis complicated by phlegmon of the perineum and scrotum in a patient with diabetes mellitus]. | | 1991 | 2056725 |
| [penoscrotal gangrene: our series of cases]. | ten cases of penoscrotal gangrene seen in our department over the last 8 years are presented. in 80% of patients causative factors of the gangrenous process were demonstrated and were equally distributed between urology and colorectal pathologies. the most commonly associated pathology was diabetes mellitus affecting up to 50% of our patients. two or more germs were isolated from the necrotic-purulent material for cultures, mainly e. coli (90%) and proteus mirabilis (50%) as aerobic organisms, a ... | 1991 | 2058440 |