Publications

[in memoriam ladislav dubay, m.d., c.sc].		1978	352528
depressant effect of sodium nitroprusside on the lower esophageal sphincter of the opossum.	in this study, we evaluated the effect of sodium nitroprusside (snp), a vascular smooth-muscle relaxant, on lower esophageal sphincter (les) pressure in the opossum. resting les pressure was monitored with a perfused sleeve sensor which allows accurate recording of les pressure irrespective of axial les motion. intravenous pulse doses and infusion doses of snp both caused significant decreases in both blood pressure and les pressure. les tone, however, was more sensitive to snp than blood pressu ...	1978	422006
[bacterial endocarditis in patients kept on regular hemodialysis].		1978	1145489
[problems of renal dysfunction in chronic renal insufficiency].		1978	1145488
[vojta's contribution to the solution of precancerous conditions in gynecology].		1978	352546
shunt quantification by mathematical analysis of indicator dilution curves.	mathematical models are presented for describing and analyzing indicator dilution curves recorded in patients with intracardiac and great vessel shunts. the models treat individual segments of the circulation as linear system blocks, each having, at its output, a characteristic time response to a rapid injection of indicator at its input. these blocks are combined in feedback and feed-forward configurations to simulate left-to-right, right-to-left, and bidirectional shunts. a shunt analysis algo ...	1978	352532
preventive dentistry in developing countries.		1978	275305
[broken appointments in the dental clinic for children].		1978	275296
[study of pancreatic exocrine function under the effect of stimulation with increased doses of secretin. ductal cellular mass and secretory capacity].		1978	1145454
sodium valproate and tardive dyskinesia.	twenty-five schizophrenic patients with tardive dyskinesia was given 600 mgs sodium valproate daily with their neuroleptic medication. after one month there was no change in their signs, as judged by a panel of nine viewing films of them taken before and at the end of this treatment.	1978	352469
continuation therapy with amitriptyline in depression.	thirty-two patients who had responded to amitriptyline (150 mg daily) when suffering from a depressive illness were allocated either to receive placebo or to remain on the same medication for one year. plasma concentrations of the drug were regularly estimated. there was no correlation between plasma concentration and subsequent residual affective morbidity. in spite of considerable encouragement, three of the patients did not take the prescribed amitriptyline and they all relapsed. five out of ...	1978	352468
autoimmune sialadenitis: possible models for sjögren's syndrome and a common aging phenomenon.		1978	2129754
professional ideology and the health care system in chile.	doctors' ideology and the role the medical profession plays in the organization and development of health services of a particular country are subjects of scientific interest. this article examines the case of chile, where doctors centralized administrative and professional power over the type of health services provided to the population. changes in this ideology throughout the century have been reflected in changes in the system of medical care. a shift can be traced from a professional ideolo ...	1978	422300
demographic growth and health needs in latin america.	the net effect of the rapid population growth in latin american countries is an increase in the needs for health services. nevertheless, the demographic factor is not the only nor the most important consideration in determining how to satisfy these demands in the region. the main contradiction lies between the magnitude of needs for services generated by the adverse living conditions prevalling among the majority of the population, together with a restricted supply of health services, the availa ...	1978	422299
automated cell sorting with flow systems.		1978	352248
[guy's hospital home dialysis program (author's transl)].	the first home dialysis was carried out from guy's hospital in london in 1968. since then, 141 patients have been treated in this manner. the age of the patients ranged from 4 to 64 years. 24 patients have died (cerebrovascular accidents, myocardial infarction, pulmonary edema, sepsis, peritonitis, hyperkalemia etc.). some of the deaths were due to a slackening of discipline on the part of the patients and nursing staff during the years of constant dialysis. of 60 adults 52 were able to start wo ...	1978	414103
nursing in europe: france.		1978	242824
multiple myeloma or benign monoclonal gammopathy? a study of differential diagnostic criteria in 44 cases.		1979	352592
studies on the mitogen responses of germfree allogeneic chimeras. i. maturation of mitogen responsiveness with duration of chimerism.		1979	352591
[postoperative jaundice].		1979	352858
[spinocellular carcinoma of the hand].	the proper treatment of squamous cell carcinoma of the hand is surgical only. radical cure and preservation of function need not exclude one another if the following points are considered: praeoperative biopsy and intraoperative pathological examination, consideration of the degree of malignancy and the possibilities of surgical reconstruction.	1979	352849
[the 80th anniversary of marc iselin].		1979	352847
[in memoriam friedrich pfeiffer, d.v.m. hannover].		1979	352662
[the use of direct skin graft and compression osteosynthesis in the treatment of secondary pseudarthrosis of the tibia].		1979	352646
endotoxins of anaerobic gram-negative rods.	endotoxic lipopolysaccharides (lps) isolated from fusobacterium are similar to those of salmonella with respect to chemical composition, o-antigenic specificity and endotoxic activity. bacteroides lps are highly atypical with respect to the chemical composition, and their endotoxic activity is low. o-antigenic specificity is present. b. fragilis lps is chemotactic for polymorphonuclear leukocytes in vitro and in vivo. the chemotactic activity is brought about by activation of the alternative com ...	1979	88759
on the occurrence of serum antibodies to bacteroides fragilis and serogroups of e. coli in patients with crohn's disease.	eight strains of bacteroides fragilis, five isolated from patients with crohn's disease and three from healthy individuals, and according to biochemical tests belonging to four subspecies, were subjected to a serologic examination with tube agglutination and passive hemagglutination (ha) tests using hyperimmune rabbit antisera. a close antigenic relationship was demonstrated between two of the strains and minor relationships between three other strains. cross absorption experiments showed that t ...	1979	88760
alterations in distribution of sudanophilic lesions in rabbits after cessation of a cholesterol-rich diet.		1979	88945
the pathophysiology of asthma.	because postmortem studies of humans provide little information on the initial pathophysiologic events in asthma, animal models have been developed. recently the ascaris-allergic rhesus monkey has provided an opportunity to examine the onset of pathophysiologic changes following challenge and to correlate them with airway structure. these studies have suggested that the initial interaction between antigen and mast cells may occur in the bronchial lumen or in the epithelium superficial to the tig ...	1979	89006
disposition of the pulmonary toxin, bleomycin.	the disposition of bleomycin in rats was investigated with the use of a 57co-labeled bleomycin radioimmunoassay. bleomycin (1 mg/kg, ip) reached a peak serum level of 0.7-1.0 microgram/ml in 54 +/- 4 min (mean +/- se) and was eliminated with a t 1/2 of 32 +/- 1 min. the apparent volume of distribution in rats was 184 +/- 11 ml/kg. no change in t 1/2 was observed when rats were pretreated with phenobarbital (1 mg/ml in drinking water for 4 days) or exposed to ozone (3 ppm, 24 hr). probenecid (0.2 ...	1979	89025
mac-1: a macrophage differentiation antigen identified by monoclonal antibody.		1979	89034
preparative isolation of the cell receptor for immunoglobulin e.		1979	89114
inheritance of tolerance susceptibility to human gamma-globulin in congenic mice.	the genetic control of susceptibility to tolerance induction with human gamma-globulin (hgg) was studied by using h-2 congenic mice. strains tested that were congenic with c57bl/10sn were completely tolerized by 1.0 mg deaggregated hgg. in contrast a/sn mice showed full tolerance whereas a.sw mice were only intermediately tolerant. it was further shown that (b10 x sjl)f1 mice could be rendered tolerant but (b10.s x sjl)f1 mice could not. these data indicate a role for h-2 linked genes in control ...	1979	89162
acid fast staining of oxidized neuromelanin and lipofuscin in the human brain.	acid fast staining of the bleached residuum of substantia nigra neuromelanin and of oxidized inferior olive lipofuscin was demonstrated in paraffin and frozen sections stained with the acetic acid, carbol fuchsin method of barbeito-lopez and the aldehyde fuchsin method of gomori. acid fast staining occurred when sections were exposed to a prestain oxidation with potassium permanganate in conjunction with a poststain differentiation with dilute hydrochloric acid. the acid fast staining with aceti ...	1979	89189
definition of cellular immune responses to brain antigens in human head trauma.	cellular immune responses to brain antigens in patients with head injury were studied by applying the leukocyte adherence inhibition (lai) assay. the investigation was conducted in three phases. 1) in the initial phase, evaluation of a series of 22 test and 25 control cases obtained at random during a 2- to 6-week time frame following a traumatic event indicated significant non-adherence of leukocytes (nal) in 77% of the test group and 20% of the control group in the presence of brain antigen. 2 ...	1979	89190
antigenic changes associated with liver carcinogenesis.	carcinogen-induced experimental hepatomas are often characterized by new individually distinct antigens capable of inducing tumor immunity in syngeneic hosts. these antigens arise as a consequence of cell-carcinogen interaction and may result from modification or replacement of normal cell-surface components. their role in immunosurveillance is not established, but they offer a target for tumor immunotherapy. reexpressed fetal antigens have also been detected, either as secretory products (alpha ...	1979	89200
the glomerulus.		1979	89456
cea-like antigens in different histologic types of human lung carcinoma.	comparative studies on the presence and immunological reactivity of cea and cea-like antigens in lung and digestive tract cancers were performed. specific goat and rabbit anti-cea immune sera were used. immunofluorescence studies revealed in histologically different types of the lung carcinomas the presence of the cross reacting antigen with classical cea. absorption procedures, and double diffusion tests have shown the existence of two at least antigenic determinants in cea molecule: 1. the det ...	1979	89630
[experimental study on intraventricular and intrathecal administration of antibiotics (author's transl)].		1979	89640
strain-specific antigens in rhizobium leguminosarum.	fifty strains of rhizobium leguminosarum, isolated from five species of host plant (pisum sativum, p. arvense, vicia sativa, v. faba, and a lathyrus sp.) were examined for the presence of strain-specific somatic antigens by immune-diffusions against 13 antisera. thirty eight strains (76 per cent) were found to belong to the same sero-group and were serologically indistinguishable from each other, but four of these strains also exhibited non-reciprocal cross reactivity with other antisera. in con ...	1979	89766
[method of preparing the tularemia antigen for an erythrocyte diagnosticum].		1979	85742
metronidazole-resistant bacteroides from untreated patient.		1979	86085
x-linked immunocompetence and epstein-barr virus oncogenesis.		1979	86133
localization of nors in chromosomes of mouse cell lines by a combined 33258-hoechst and ag-staining technique.		1979	84805
rapid diagnosis of bacteroides infections by indirect immunofluorescence assay of clinical specimens.	43 specimens from a variety of sites were directly examined by indirect immunofluorescence assay (i.f.a.) with specific antisera against the capsular polysaccharide of bacteroides fragilis and pooled antisera against a number of serotypes of bacteroides sp. (all of the former b. fragilis subspecies). the findings were compared with those of routine anaerobic bacteriology and gas liquid chromatography for short chain fatty acids. examination by i.f.a. was a sensitive (100%) and specific (90.3%) m ...	1979	84899
highly purified insulins.		1979	85008
intracellular polysaccharide of bacteroides fragilis.	formation of iodophilic polysaccharide (ips) from glucose was demonstrated in 27 strains of bacteroides fragilis. synthesis was dependent on the glucose concentration of the medium, the ph and the growth phase. when glucose was in short supply the cellular polysaccharide was degraded rapidly at ph 4.5 to 6.5 and fatty acids accumulated in the medium. storage of ips was not responsible for the low carbon recoveries observed in fermentation balance studies. in electron micrographs of thin sections ...	1979	37285
antibiotic susceptibility of anaerobic bacteria with special reference to bacteroides fragilis.	it was shown that recent swedish clinical isolates of anaerobic bacteria are susceptible to many antibiotics by the agar dilution method with the exception of the bacteroides group versus beta-lactam antibiotics or tetracyclines. strains of b. fragilis were inhibited by 4--greater than 128 micrograms benzylpenicillin or cephalothin/ml, 1.0--64 micrograms cefoxitin/ml, 0.064--2 micrograms clindamycin or metronidazole/ml, 2--8 micrograms chloramphenicol/ml, 2--16 micrograms fusidic acid/ml and 0.0 ...	1979	37593
[anaerobic gram negative septicemias in digestive tract surgery and in surgical intensive care].		1979	39472
characterization of anaerobic gram-negative bacilli by using rapid slide tests for beta-lactamase production.	a total of 175 isolates of anaerobic gram-negative bacilli were tested for beta-lactamase production by using a slide test modification of the chromogenic cephalosporin (nitrocefin, glaxo, middlesex, england) assay and the iodometric slide test. included isolates were bacteroides melaninogenicus (46), b. fragilis (78), other bacteroides isolates (21), fusobacterium (25), and other gram-negative bacilli (5). both slide tests detected 25 b. melaninogenicus isolates that were beta-lactamase produce ...	1979	41001
anaerobic isolates in chronic recurrent suppurative otitis media. treatment with carbenicillin alone and in combination with gentamicin.	tympanocentesis was performed in 32 pediatric patients with chronic recurrent suppurative otitis media. the aspirate was cultured aerobically and anaerobically. aerobes were isolated from ten patients (31.2%); anaerobes from one patient; and both aerobes and anaerobes from 21 patients (65.6%). there were 46 aerobic isolates. the aerobes commonly recovered were pseudomonas aeruginosa (24 isolates) proteus sp. (5) and staphylococcus aureus (3). there were 32 anaerobes isolated including anaerobic ...	1979	41811
fluorescent antibody test kit for rapid detection and identification of members of the bacteroides fragilis and bacteroides melaninogenicus groups in clinical specimens.	the fluoretec fluorescent antibody test kit (pfizer inc., new york, n.y.), developed for the rapid detection of members of the bacteroides fragilis and b. melaninogenicus groups, was evaluated by testing 58 stock cultures and 76 clinical specimens. the test reagents detected 100% of 40 b. fragilis and b. thetaiotaomicron stock culture strains, although only 22% of 18 b. vulgatus, b. distasonis, and b. ovatus strains showed positive fluorescence. the 76 clinical specimens were evaluated by examin ...	1979	41847
rapid diagnosis of anaerobic infections by gas-liquid chromatography.	it was postulated that the short chain fatty acids (scfa) produced by anaerobic bacteria might serve as microbial markers in purulent material. eighteen pus specimens from various sources were analysed by gas-liquid chromatography (glc), and the scfa detected were compared with the microorganisms isolated by conventional methods. it was found that the detection of propionic, isobutyric, butyric, or isovaleric acids by direct glc of pus specimens is strong evidence for anaerobic infection but not ...	1979	41850
virulence factors of anaerobic bacteria: summary of the symposium.		1979	44924
chromogenic cephalosporin spot test to detect beta-lactamase in clinically significant bacteria.	lactamase production. reacteroides melaniongenicus, 14	1979	34624
anaerobic subareolar breast abscess.	15 non-puerperal women with breast abscess were seen during one year. in 8, anaerobes were cultured from pus obtained from the abscess, in 6, staphylococcus aureus was grown, and in 1 the pus was sterile on culture. all 7 breast abscesses in puerperal women seen during the same period were staphylococcal. the anaerobic abscesses were all subareolar; they were recurrent in 4 patients and were associated with retracted nipples in 7. the anaerobes isolated were those found as normal commensals in t ...	1979	83476
bacteroides species in subareolar breast abscess.		1979	84281
diisopropylfluorophosphate-evoked inhibition of anaphylactic histamine release from human skin: decrease of the inhibition by storing the skin specimens.	antigen-induced histamine release from human skin slices passively sensitized with reaginic serum in vitro was inhibited by dfp, suggesting involvement of serine esterase activation in the reaction. the magnitude of dfp-evoked inhibition of the histamine release was not the same in each skin sample and no correlationship was observed between the magnitude of the dfp-evoked inhibition of the histamine release and that of the histamine release in the absence of dfp. the magnitude of the histamine ...	1979	84487
coupling between neuronal activity and focal blood flow in experimental seizures.	local blood flow, ecog and single cortical neurone activity were recorded simultaneously from single microelectrodes in 17 cats. seizures were induced by repeated intravenous injections of pentylenetetrazol (ptz, 10-20 mg/kg) or by local application of 1 m na-penicillin. seven to 20 sec after appearance of burst activity in cortical neurones and ecog, focal flow increased up to 300% of control. the extent of this flow increase was significantly correlated with the change in firing rate of the ne ...	1979	89943
a functional measure of brain activity: brain stem transmission time.	surface-recorded auditory nerve and brain stem responses are being used routinely for diagnostic purposes in man. when interest is in auditory diagnosis, the electric response threshold is of primary importance. however, when used in neurological diagnosis, the wave form of the response is important. as a measure of one aspect of response wave form, this paper suggests the use of brain stem transmission time (btt), defined as the time interval between the first earlobe-negative wave (response of ...	1979	89952
vasoactive intestinal peptide (vip) stimulates prolactin (prl) release and camp production in a rat pituitary cell line (gh3/b6). additive effects of vip and trh on prl release.		1979	89971
ribosomal ambiguity (ram) mutations facilitate diyhydrostreptomycin binding to ribosomes.		1979	89972
distribution of myosin isoenzymes among skeletal muscle fiber types.	using an immunocytochemical approach, we have demonstrated a preferential distribution of myosin isoenzymes with respect to the pattern of fiber types in skeletal muscles of the rat. in an earlier study, we had shown that fluorescein-labeled antibody against "white" myosin from the chicken pectoralis stained all the white, intermediate and about half the red fibers of the rat diaphragm, a fast-twitch muscle (gauthier and lowey, 1977). we have now extended this study to include antibodies prepare ...	1979	90047
comparative serology of two clinical isolates of bacteroides fragilis and bacteroides thetaiotaomicron.	antiserum prepared in rabbits against bacteroides fragilis showed numerous bands when reacted with b. fragilis antigen in ouchterlony plates. this antiserum also reacted with bacteroides thetaiotaomicron and showed one band of apparent identity with b. fragilis. the band of identity common for both organisms was lost if the antigen was heated at 80 degrees c for 30 min. antisera prepared against b. thetaiotaomicron did not react with b. fragilis.	1979	90054
the histochemical distribution of protein bound sulfhydryl groups in human epidermis by the new staining method.	recently, we synthesized a new fluorescent thiol reagent, n-(7-dimethylamino-4-methylcoumarinyl)-maleimide (dacm) which is nonfluorescent by itself but will react readily with -sh groups to form highly fluorescent addition products. by the use of this reagent, we studied the localization and concentration of -sh groups and s--s linkages in the human epidermis. the distribution of -sh groups in living layers was abundant in cytoplasm but not in nuclei. the fluorescence was concentrated on the cel ...	1979	90070
the use of avidin-biotin interaction in immunoenzymatic techniques.	biotin was covalently attached to antibodies, antigens and enzymes, and the effects of this labeling on the antigen and antibody binding capacity and on enzymatic activity were tested. based on avidin-biotin interaction, the labeled proteins were used in quantitative enzyme-immunoassay and enzyme-immunohistochemical staining procedures. two procedures were developed. in the first procedure, named the bridged avidin-biotin (brab) technique four steps were used sequentially in order to quantify or ...	1979	90074
effects of arachidonic acid and its metabolites on antigen-induced histamine release from human basophils in vitro.		1979	90097
rapid detection of malaria and other bloodstream parasites by fluorescence microscopy with 4'6 diamidino-2-phenylindole (dapi).	dapi is a fluorescent dye which appears to complex specifically with dna. we have used this probe to detect and identify malarial infections by fluorescence microscopy. experiments were conducted using plasmodium berghei yoeli--infected mouse blood, p. lophurae--infected duck blood, and p. vivax--infected human blood. infected avian blood was used to detect parasites within nucleated erythrocytes. control blood smears from uninfected hosts revealed fluorescence only in the leukocytes of mammalia ...	1979	90141
structure of products of the moloney murine leukemia virus endogenous dna polymerase reaction.	we have investigated the process by which the single-stranded rna genome of moloney murine leukemia virus is copied into dna in vitro. dna synthesis if initiated near the 5' end of the genome, and the elongation of the growing chain occurs by a jumping mechanism whereby the dna synthesized at the 5' end of the genome is elongated along the 3' end. unique dna fragments synthesized beyond the 5' end of the genome in vitro have, at their 5' and 3' ends, copies of unique sequences from the 5' and 3' ...	1979	90161
steroid treatment of male subfertility caused by antisperm antibodies.	47 subfertile men with significant titres of antisperm antibodies were treated with one of two steroid regimens. the results were assessed by changes in sperm-counts and in serum antibody titres and by subsequent pregnancies. 15 oligozoospermic men were treated with prednisone 5 mg three times a day for 3--12 months. sperm-counts became normal in 10 men and 4 of their wives became pregnant. 14 men with normal sperm-counts received the same treatment: antibody titres fell slightly and 3 of their ...	1979	90218
surface structure of mammalian articular cartilage viewed at low temperature.		1979	90268
polyribonucleotide inhibition of ribonucleic acid directed deoxyribonucleic acid polymerase of mouse mammary tumor (type b) virus and simian sarcoma (type c) virus.		1979	90331
the elephant man.		1979	90342
detection by antihapten antibodies of liver-bound compounds related to azocarcinogens or their metabolites.	the localization of known azocarcinogens and metabolites such as p-aminoazobenzene and n-methyl-p-aminoazobenzene bound to components of liver cells of rats fed single or multiple doses of 3'-methyl-p-dimethylaminoazobenzene has been determined with the use of antibodies raised against p'-azo-p-aminoazobenzene and p'-azo-n-monomethyl-p-aminoazobenzene in the indirect fluorescent antibody procedure. these 2 antisera reacted with liver cells of rats fed 3'-methyl-p-dimethylaminoazobenzene, p'-amin ...	1979	90352
[pharmacological properties and antitumor activity of a preparation diiodo-benzo-tepa in experiments].	experimental data on the pharmacokinetics, toxicity, antitumor activity of the antitumor drug diiodo-benzo-tepa are reported.	1979	90429
the expression of a human b-lymphocyte antigen and surface membrane immunoglobulin by lymphoid cells from patients with lymphocytic lymphoma, multiple myeloma and benign monoclonal gammapathy.		1979	90449
isolation and immunological reactivity of soluble fractions from rat seminiferous tubule basement membrane.	a preparation rich in basement membranes isolated from rat testes (stbm) was exposed to pepsin, collagenase, trypsin, and pronase to obtain soluble fractions. the immunological reactivity of these fractions was studied by gel immunodiffusion or by passive hemagglutination tests against an anti-stbm serum. all fractions reacted with the antiserum, but the highest titer was detected when the antiserum was reacted with a fraction that contained only traces of hydroxyproline (fraction 1), whereas lo ...	1979	90490
strain differences in tolerance induction to human gamma-globulin subclasses: dependence on macrophages.		1979	90559
in vitro studies of the replication of moloney murine leukemia virus.		1979	90575
the intra-nucleolar localization of amplified rdna in xenopus laevis oocytes.	a fluorescent feulgen-stain was adapted in order to demonstrate dna-containing structures inside the amplified nucleoli of xenopus laevis. at all stages of oogenesis this method reveals granules or complex structures of dna in each nucleolus. the micronucleoli which do not stain with this method and which do not reveal an internal structure in low molarity saline, unlike real nucleoli are considered as nucleolus-like bodies. the dna-containing structures in the nucleoli can be composed of one or ...	1979	90588
biosynthesis of a blood-group-i determinant reacting with anti-i ma serum (group 1).	a blood-group-i determinant reacting specifically with anti-i ma serum (group 1) has been produced biosynthetically by the action of a beta-galactosyl transferase isolated from human milk on a precursor glycoprotein produced by formic acid hydrolysis and beta-d-galactosidase action on blood-group h substance prepared from hog gastric mucosa.	1979	90615
[animal experimental studies on the volume expanding effect of hydroxyethyl starch 40000 in the dog acute hemorrhagic shock].	after acute hemorrhagic shock in dogs the hemodynamics of hydroxyethyl starch (mw: 40,000) are studied. the experiment shows that this plasma expander has a good efficiency for 3 to 4 hours. the indications of application of this colloidal solution are discussed.	1979	90651
[concerning the contribution by f. jesch, g. hübner, v. zumtobel, m. zimmermann and k. messmer, hydroxyethyl starch (has 450/0,7) in plasma and liver--course of concentration and human histologic changes [infusionstherapie 6:112-117 (1979)].		1979	90652
the indirect rat mast cell degranulation test reconsidered.	the indirect rat mast cell degranulation test for the detection of human reaginic antibodies was reinvestigated. when the mast cells were incubated with human reaginic serum at concentrations exceeding approximately 3%, a massive, non-specific histamine release occurred, irrespective of the presence or absence of allergen. at tolerated serum concentrations (below 3%), the allergen concentration did not influence the release process. we conclude that the indirect rat mast cell test is not applica ...	1979	90655
antigens in penicillin allergy. iv. induction of ige antibody response in mice after daily treatment with contaminated but not with pure penicillin.		1979	90657
characterization of a type-c virus produced by co-cultures of human leukemic bone-marrow and fetal canine thymus cells.	the putative human helper virus ska-21/a204v, isolated by nooter et al. in 1977 from human leukemic bone-marrow cells following co-culture with normal fetal canine thymus cells, cf2th, has been characterized with respect to its major viral core protein, reverse transcriptase, and nucleic acid sequences. the results of these analyses show that this virus is not distinguishable from the woolly monkey type-c virus, ssav-1, by the techniques employed.	1979	90662
purification of a new high activity form of glucose-6-phosphate dehydrogenase from rat liver and the effect of enzyme inactivation on its immunochemical reactivity.	a new form of cytoplasmic glucose-6-phosphate dehydrogenase (e.c.1.1.1.49) was purified from rat liver by protamine sulfate precipitation, ammonium sulfate fractionation, ion exchange chromatography with diethylaminoethyl cellulose, and affinity chromatography with cibacron blue agarose and nadp agarose. this form of the enzyme has a specific activity of over 600 units/mg of protein and gives essentially a single band by polyacrylamide gel electrophoresis. the form of the enzyme isolated by this ...	1979	90677
schistosome patterns in egypt.		1979	90881
metronidazole in large-bowel surgery.		1979	90991
soluble immune complex disease associated with antigen heterogeneity an hla related disorder.	it is suggested that soluble immune complex diseases arising after infections may result from the liberation of partially synthesized bacterial polypeptide or viral nucleic acid antigens. these disrupted antigens will have heterogeneous molecular weights due to antigenic material which is incomplete as a result of premature termination of synthesis. antigens of this type have been shown to result in significant soluble complex formation in vitro when reacted with antisera from many individuals. ...	1979	91086
[effect of human antigens on the biological properties of the causative agents of typhoid fever and paratyphoid b].		1979	91281
the specificity of nonspecific concanavalin a-induced helper factors.		1979	91523
molecular hybridization probes for research in liver disease: studies with albumin cdna.	a major avenue of our research has been to develop molecular probes (cdnas) for studying the pathogenesis of liver disease (i.e., applied molecular pathophysiology). during the last 2-3 yr, we have developed and used molecular hybridization to study regulation of albumin synthesis in normal, protein-calorie deprived, uremic, and cirrhotic rat liver. our current work is directed toward cloning the albumin gene to permit further analysis of albumin transcriptional and posttranscriptional control. ...	1979	91541
radioprotection of mouse intestine by inhibitors of cyclic amp phosphodiesterase.		1979	91600
immunochemical evidence for multiple serotypes of bacteroides fragilis.	an immunochemical comparison of outer membrane antigens obtained from five select and biochemically defined strains indicated that there are several serotypes of bacteroides fragilis. each strain was serologically defined by individual or by combinations of determinant groups composed of carbohydrates in the form of polysaccharides or glycoproteins. the carbohydrate constituents were tentatively identified as glucose, galactose, fucose, rhamnose, glucosamine, galactosamine, and traces of mannose ...	1979	91622
binding of purified, soluble major histocompatibility complex polypeptide chains onto isolated t-cell receptors. i. reactivity against allo- and self-determinants.	in this study, we tried to get information about the fine antigen-binding ability of purified, soluble, idiotype-positive t-cell receptor molecules. lewis anti-da t-cell receptors were purified from normal lewis serum by the use of anti-idiotypic immunosorbent and sodium dodecyl sulfate-polyacrylamide gel, and were coupled to cyanogen bromide-activated sepharose 4b. in parallel, lewis anti-da, lewis anti-bn, and da anti-lewis alloantibody immunosorbents were prepared. the major ag-b chain (44,00 ...	1979	91653
trace polypeptides in cellular extracts and human body fluids detected by two-dimensional electrophoresis and a highly sensitive silver stain.	development of a highly sensitive silver stain permits the characterization of trace cellular and body fluid proteins separated by the two-dimensional electrophoresis technique of o'farrell. many of the proteins detected by the silver stain in urine, spinal fluid, amniotic fluid, and cells were undetected with the widely used coomassie blue stain. trace polypeptides observed in escherichia coli cell lysates with this silver stain could be detected previously only by growth in radioactive precurs ...	1979	92027
epithelioid sarcoma: ultrastructural observation of lymphoid cell-induced lysis of tumor cells.	epithelioid sarcoma of the palm of 7 months' duration was observed in a 30-year-old man. six months after wide surgical excision there was no evidence of recurrence or metastasis. by light microscopic examination the tumor showed typical nodular arrangement of malignant cells, with necrosis of these cells in the centers of the nodules. patchy lymphocytic infiltrates were observed at the peripheries of the nodules and also extended in places between the tumor cells. other types of inflammatory ce ...	1979	92147
sodium dodecyl sulphate interactions with mouse interferon [proceedings].		1979	92245
membrane-bound mitochondrial dna: isolation, transcription and protein composition.	mitochondrial membrane-bound dna complex from bovine heart mitochondria lysed in the presence of triton x-100 was isolated by differential centrifugation. the yield of "nucleoid" is about 30 microgram protein/mg mitochondrial protein. it contains about 3-5 microgram dna/mg protein and varying amounts of rna. the heart mitochondrial nucleoid actively synthesizes rna. the nucleoid fraction contains about sixteen different proteins as evidenced by urea-sds gel electrophoresis and about twenty-one p ...	1979	92288
immunologic regulation in pregnancy.	theories to explain the failure of rejection of the fetus by the mother during pregnancy include immunologic privilege of the uterus as a graft site, lack of transplantation antigen expression on the trophoblast, weakening of maternal cellular immunity during pregnancy, and separation of maternal and fetal circulations. evidence for and against each of these theories is discussed. local concentration of a variety of hormones, including human chorionic gonadotropin (hcg), sex steroids, alpha-feto ...	1979	92318