Publications

[increase of anaerobic infections. prevalence of bacteroides. apropos of 17 cases in abdominal surgery].	seventeen cases of anaerobic infections in abdominal surgery are reported. predominance of bacteroides is evident (9/17), especially bacteroides fragilis. the clinical manifestations of bacteroides infections are severe: 7 septicemias and 2 parietal infections, being the cause of the death in four patients. bacteroides infection develops preferently in an old patient, with severe disease, in colic surgery especially in emergency. bacteroides are characterized by their polyresistance to antibioti ...	1977	900536
bacteroides fragilis infections of the urinary tract.		1977	903332
susceptibility bacteroides fragilis to fusidic acid.		1977	903333
[appearance of metronidazole resistance in bacteroides fragilis].		1977	905136
the cephalosporins.	cephalosporin antibiotics are bactericidal against most gram-positive cocci and many gram-negative bacilli of clinical importance. they are relatively nontoxic but share with penicillins a tendency to elicit hypersensitivity reactions. they are indicated in certain instances for treatment of infections in patients with penicillin allergy and are frequently chosen as one of the agents in an empiric program in life-threatening infections. cephalosporins should not be used in infections caused by g ...	1977	909313
[bacteroides fragilis septicemia during rheumatoid arthritis].		1977	909745
in vitro activity of five oral cephalosporins against anaerobic pathogenic bacteria.	the in vitro inhibitory activities of cefaclor and and cefatrizine, two new orally absorbed cephalosporin antibiotics, against 44 isolates of anaerobic pathogenic bacteria were measured using the agar dilution procedure of the world health organization-international collaborative study. tests also were performed with cephalexin, cephaloglycin, and cephadrine, as well as with the parenteral cephamycin antibiotic cefoxitin. cefoxitin was the most active antibiotic and inhibited the majority of iso ...	1977	915342
[evaluation of the disc-plate method in bacteroides fragilis].		1977	918321
requirement of heme for growth of bacteroides fragilis.	heme or protoporphyrin ix was required for growth of bacteroides fragilis in a defined medium. the amount of heme necessary for half-maximal growth was 2 to 10 ng/ml (3.8 to 15 pmol/ml) among the bacteroides species and strains tested. the growth rate, metabolic products from glucose fermentation, and cell yields were affected by the concentration of heme in the medium and by the length of time the culture was incubated. when heme was growth limiting (4 ng/ml), growth rates decreased by 50%, cul ...	1977	921263
treatment of cerebral abscesses.		1977	922393
bacteriological study of otogenic cerebral abscesses: chemotherapeutic role of metronidazole.	in nine consecutive patients with otogenic cerebral abscesses a mixed growth of aerobic and obligate anaerobic bacteria was isolated from the pus in five patients, and in the remaining four obligate anaerobes were the sole isolates. the commonest obligate anaerobe isolated was bacteroides fragilis, which was present in all but one patient. the patients were all treated with metronidazole for the anaerobic organisms and with appropriate chemotherapy against the aerobic organisms isolated. all the ...	1977	922400
evaluation of kanamycin-esculin bile agar for isolation and presumptive identification of bacteroides fragilis group.	a kanamycin-esculin bile medium was useful for selective isolation and presumptive identification (24 h) of the bacteroides fragilis group.	1977	925149
the germicidal effect of the open air in different parts of the netherlands.	using the microthread technique the survival of escherichia coli mre 162 in open air was measured in different parts of the netherlands. the presence of bactericidal compounds (open air factor = oaf) could be demonstrated on several days and quantitated in relative units of oaf concentration. in the absence of ozone the oaf concentration was always low. in the presence of ozone the oaf concentration was dependent on wind direction. at the selected microthread exposure sites air from areas with h ...	1977	321676
human biology council.		1977	326655
repair, replication and survival in uv-irradiated escherichia coli.	the influence of dimer removal through excision or photoreactivation on the kinetics of dna synthesis, sedimentation profiles of dna molecules and survival of cells was investigated in excision-deficient and excision-proficient escherichia coli k-12 after a flux of 20 j m-2. in excision-deficient cells photoreactivation did not influence the kinetics of dna synthesis for a long period and the sedimentation properties of dna synthesized immediately after photoreactivation were influenced only sli ...	1977	321311
effect of some bacterial products on platelet electrophoretic mobility (pem).	bacterial lps, used in our experiments, are able to decrease pem at concentration of 100 microgram/ml after incubation with 1 x 10(7) platelets/ml for 30 min at 37 degrees c. such effect is statistically significant for bacteroides fragilis lps, s. enteritidis and s. typhi. e. coli lps 026:b6 w and e. coli 055:b5 w are not effective at all, s. minnesota (incomplete) lps 595 and 345 free of 0-polysaccharide and partially lacking core in their molecule did not influence pem, while s. minnesota lps ...	1977	410424
acute pelvic inflammatory disease.		1977	412258
anterograde transneuronal degeneration in the limbic system: clinical-anatomic correlation.	a 64-year-old man with diffuse atherosclerosis developed an organic mental syndrome, followed by hypothalamic symptoms. autopsy showed an old large cystic infarct involving the left temporal lobe including the hippocampus, and atrophy of the ipsilateral fornix, mammillary body, hypothalamus, mammillothalamic tract, and the anterior thalamic nucleus. the clinical deterioration and pathologic findings may be explained by anterograde transneuronal degeneration within the limbic system following the ...	1977	412120
[bacteroides fragilis (author's transl)].		1977	559144
[anaerobic bacterial infections (author's transl)].		1977	560553
office treatment of anaerobic infections.		1977	561288
[isolation of anaerobic bacteria from clinical specimens and the drug susceptibility of bacteroides fragilis].	in the routine bacteriological examination of 8,423 clinical specimens, 906 strains of anaerobic bacteria were isolated at national taiwan university hospital between april 1972 and april 1976. most of the strains were isolated from sites allied to the abdominal cavity and genito-urinary tract. bacteroides fragilis was the most commonly isolated pathogen. the minimal inhibitory concentrations of 10 different antimicrobial agents to 74 clinical isolates of b. fragilis were determined by an agar d ...	1977	578133
doxycycline in abdominal surgery.	twenty patients undergoing urgent or emergency surgical procedures where intra-abdominal infection was suspected were treated with doxycycline hyclate. wound infections involving anaerobic, aerobic, or facultative bacteria developed in four of 11 patients treated with doxycycline alone. nine other patients received higher doses of doxycycline plus gentamicin sulfate. five of these had postoperative infections primarily involving anaerobic organisms. bacteremia with a doxycycline-resistant bacter ...	1977	578553
susceptibility to erythromycin of anaerobes of the genera bacteroides, fusobacterium, sphaerophorus, veillonella, clostridium, corynebacterium, peptococcus, peptostreptococcus.	the minimal inhibitory concentrations (mic) of erythromycin were determined by broth dilution tests for 313 anaerobic strains, most of which were clinical isolates. all the gram-positive anaerobes tested (84 peptococcaceae, including 21 peptostreptococcus anaerobius and 15 peptococcus variabilis; 65 corynebacterium acnes and 29 clostridium strains, including 13 c. perfringens) were sensitive (mic values 0.012 through 3.12 microgram erythromycin/ml); so were 111 cultures of gram-negative anaerobe ...	1977	580038
[anaerobic infections].		1977	584899
[in vitro activity of mezlocillin, azlocillin and carbenicillin against bacteroidaceae with particular reference to bacteroides fragilis (author's transl)].	the in vitro susceptibility of approximately 90 bacteroidaceae strains to the the new broad-spectrum penicillins mezlocillin and azlocillin was determined by tube dilution tests and compared to susceptibility to carbenicillin. bacteroides fragilis and bacteroides thetaiotaomicron predominated among the strains tested. these strains are particularly important as pathogens and are known to produce beta-lactamase. at concentrations of 16 microng/ml or less, mezlocilin inhibited 81% of the bacteroid ...	1977	585371
susceptibility of bacteroides to noxythiolin.		1977	589283
the degradation of cholic acid and deoxycholic acid by bacteroides species under strict anaerobic conditions.		1977	598575
an h.p.l.c. assay for cephalosporinase activity.		1977	599089
bactericidal activity of metronidazole, tinidazole and ornidazole against bacteroides fragilis in vitro.		1977	599119
discrepant behaviour of clotrimazole against bacteroides fragilis in liquid and solid media.		1977	599124
erythromycin and anaerobic infection.	the theoretical basis of the use of erythromycin in peri-operative prophylaxis after bowel surgery will be discussed and the results of the use of erythromycin in such patients and the sensitivity to the antibiotic of isolates from human peritonitis described. this work will be related to results obtained in a rabbit experimental model for the study of peritonitis.	1977	601557
lethality for mice and chick embryos, pyrogenicity in rabbits and ability to gelate lysate from amoebocytes of limulus polyphemus by lipopolysaccharides from bacteroides, fusobacterium and veillonella.	phenol-water extracted lipopolysaccharides (lps) from veillonella, fusobacterium nucleatum, bacteroides fragilis and bacteroides melaninogenicus were lethal for mice and 11-days-old chick embryos, pyrogenic in rabbits, and gelated limulus amoebocyte lysate. mouse lethality was considerably enhanced by actinomycin-d. in all test systems the endotoxin activity of veillonella and fusocbacterium lps was comparable to that of lps from salmonella enteritidis, which was included as a reference endotoxi ...	1977	564596
[electromagnetic therapy in inflammatory processes of the larynx and trachea].		1977	352011
[various principles and trends in the development of current transplantology (scientific prognosis)].		1977	352003
the laboratory diagnosis of megaloblastic anemias.	the diagnostic approach to megaloblastic anemia involves four usually sequential steps. the first step, recognition of megaloblastosis, requires attention to altered blood cell size and morphology. these changes may sometimes be subtle or masked. the cornerstone of the second step, identification of the specific vitamin deficiency, is assay of serum vitamin b(12) and folic acid levels, although they may occasionally be misleading. the third step, identification of the specific disease entity res ...	1977	351964
the effects of a clamping regime on voiding dysfunction rate after low anterior resection and abdominal-perineal resection.		1977	274524
injection of corticosteroids into mother to prevent neonatal respiratory distress syndrome.	in this study, 500 mg. of hydrocortisone were injected intravenously into 126 women every 12 hours for four doses in a double-blind, randomized fashion. these 126 subjects were at risk for delivery of a premature infant because of premature labor of fetomaternal disease necessitating intervention. there were 67 patients in the treatment group and 59 in the placebo group. all patients had immature lecithin/sphingomyelin ratios and/or were at less than 34 weeks' gestation. from these data, it appe ...	1977	352152
proliferative vitreoretinopathy.		1977	2129936
[testing of the marginal closure of so-called carvable composites].	66 composite filings of the brands classecond, epoxydent and compocap were examined for marginal fit. the two first brands can be carved, the latter cannot. the fillings were examined by vacuum color diffusion tests, and replicas of the fillings were viewed with the em. 91% of the compocap fillings were found to be color impermeable, while 64% of the epoxydent and 55% of the classecond fillings proved to be leaking at the margins. the em examination showed that carving the fillings causes consid ...	1977	274809
hypofibrinolysis in patients with a history of idiopathic deep vein thrombosis and/or pulmonary embolism.	an impaired fibrinolytic activity after a venous occlusion test is the most common abnormality associated with thomboembolic disease. to better characterize the causes of abnormal responses we have measured different fibrinolytic parameters, before and after 10 and 20 min of venous occlusion, in 77 patients with a history of idiopathic deep vein thrombosis and/or pulmonary embolism and in 38 healthy volunteers. the patients had a lower mean fibrinolytic response to venous occlusion than the cont ...	1977	1631786
pneumonia in multiple myeloma: a case report.		1977	274786
[sequence and method of education of patients with diabetes mellitus: a case studied at a research group for management of diabetes mellitus].		1977	242668
cicatricial pemphigoid.		1977	352096
[membership list. royal belgian society of gastroenterology].		1977	352080
carcinoembryonic antigen.		1977	274620
termination of pregnancy in gisborne.	the 182 abortion cases referred to the cook hospital in gisborne, new zealand from november 1973 to december 1975 were analyzed in regard to referral patterns, operative methods, pregnancy duration prior to abortion, complication rates, and patient characteristics, including their contraceptive practices before and after abortion. the results of the analysis were compared to data on a series of new zealand women who obtained abortions in melbourne, and to abortion data obtained from the auckland ...	1977	274617
the psychopathology of psychiatric consultation: a different view.		1977	421454
adherence of bacteroides fragilis in vivo.	the ability of the encapsulated species bacteroides fragilis to adhere to rat peritoneal mesothelium was compared to the adherence of unecapsulated strains of bacteroides (b. distasonis, b. vulgatus, b. thetaiotaomicron, b. ovatus, and b. "other"). adherence was assayed by attaching plexiglas plates containing 8-mm holes to the peritoneal mesothelium of anesthetized rats. cell suspension (0.25 ml) was incubated in each well, after which the suspension was aspirated, and a 4-mm punch biopsy was r ...	1978	640723
encapsulation of bacteroides species.	capsules were detected by the india ink method in cultures of bacteroides fragilis, b. vulgatus, b. thetaiotaomicron, and b. ovatus. no capsules were found in the five strains of b. distasonis examined.	1978	640724
[infections caused by bacteroides fragilis resistant to clindamycin: 2 further cases].		1978	643586
use of high-pressure liquid chromatography to determine plasma levels of metronidazole and metabolites after intravenous administration.	a rapid and sensitive high-pressure liquid chromatography assay for metronidazole and its two principle metabolites, 1-(2-hydroxyethyl-2-hydroxymethyl)-5-nitro-imidazole [hydroxy metabolite] and 1-acetic acid-2-methyl-5-metronidazole [acid metabolite], was developed. the retention times observed were 5.7, 3.3, and 4.5 min, respectively. a reverse-phase muc(18) bondapak column using a solvent system of methanol, acetonitrile, and 0.005 m ph 4 potassium dihydrogen phosphate (4:3:93, vol/vol) was u ...	1978	646342
bacteroides fragilis endotoxin-induced histopathological lesions in mice and rabbits.		1978	647432
enhancement of experimental anaerobic infections by blood, hemoglobin, and hemostatic agents.	certain foreign materials have been demonstrated to enhance the infectivity of aerobic and anaerobic bacteria. whole blood and other protein compounds encountered in surgical settings or trauma were tested for their effect on infectivity of nonsporeforming anaerobic bacteria. infectious synergistic mixtures of bacteroides fragilis plus peptostreptococcus anaerobius and bacteroides melaninogenicus plus fusobacterium necrophorum were each diluted to a barely noninfectious or minimally infectious c ...	1978	631883
breakdown of psyllium hydrocolloid by strains of bacterioides ovatus from the human intestinal tract.	strains of bacteroides ovatus from human feces produced extracellular enzymes which degraded psyllium hydrocolloid. other species of saccharolytic bacteria which are found in high concentrations in human feces did not degrade psyllium.	1978	647481
the role of bacteroides fragilis in abcesses of the central nervous system: implications for therapy.		1978	624699
the bacteriology of cavitating pulmonary infections and empysema. studies of transtracheal aspirates and pleural fluid.	a prospective study of bacteriology in 14 cases of cavitating pulmonary infections and empyema is reported. bacteriologic results were based on transtracheal aspirates or pleural fluid. appropriate anaerobic bacteriologic methods were employed. anaerobic bacteria were recovered in 11 patients (79%); they were the only pathogens isolated in 6 patients. the predominant species were fusobacterium nucleatum, bacteroides melaninogenicus, bacteroides fragilis and peptostreptococcus. aerobic bacteria w ...	1978	352421
rabbit polymorphonuclear leukocyte chemotactic factor generated in vivo by bacteroides fragilis lipopolysaccharide. i. isolation and physico-chemical characterization.	by chromatographic separation on sephadex gels a peptide, termed the lipopolysaccharide-induced chemotactic factor (lps-cf), has been isolated from inflammatory exudate. the exudate was obtained from teflon chambers implanted subcutaneously in rabbits 3 h after lps from bacteroides fragilis ss. fragilis had been injected. three chemotactic peaks were eluted by fractionation of the exudate on sephadex g-200 columns; one major peak with molecular weight of approximately 16,000 and two minor peaks ...	1978	358747
a study of the surface and somatic antigens of bacteroides fragilis.	antisera against live cultures of 20 strains of bacteroides fragilis produced in rabbits agglutinated homologous whole-cell as well as o-antigen suspensions with several cross-reactions. pure specific antisera were produced by absorbing cross-reacting antigens. o-antisera reacted against o-antigens but failed to do so against most whole-cell suspensions, suggesting the presence of surface structures which might have blocked the reactions. the titres of the whole-cell antisera were not significan ...	1978	649950
inactivation of penicillin g during experimental infection with bacteroides fragilis.	an animal model implanted with intraperitoneal plastic reservoirs was used for study of the penetration of penicillin g into sites infected with bacteroides fragilis. penicillin g was given to rabbits, and its concentration in uninfected reservoirs and in those infected with b. fragilis was determined. the mean percentage penetration ([concentration in capsule divided by peak concentration in serum] x 100) of penicillin into uninfected capsules was 19.9%, whereas that into heavily infected capsu ...	1978	649987
clinical experience with cefamandole for treatment of serious bone and joint infections.	the safety and efficacy of treatment with cefamandole were evaluated in 30 patients (from 18 institutions) with serious bone and joint infections. five of the subjects were children. the antibiotic was given intramuscularly or intravenously in doses ranging from 2 to 12 g daily for five to 44 days. twenty-six of the 30 patients responded satisfactorily. fourteen of the fifteen infections due to staphylococcus aureus were among the successful cases. other pathogens were streptococci, escherichia ...	1978	649996
a case of septic arthritis in multiple joints due to bacteroides fragilis in a patient with rheumatoid arthritis.	a case of arthritis in multiple joints due to b. fragilis ssp. fragilis is described. the patient was a 55-year-old man badly disabled by rheumatoid arthritis. the patient's immune response to the isolated strain was studied and a significant titre reduction during the course of the disease was observed. the serum antibodies of the patient cross-reacted with heterologous strains of b. fragilis ssp. fragilis. it is suggested that indirect immunofluorescence tests against a certain number of b. fr ...	1978	654904
quantitative gas chromatography of bacteroides species under different growth conditions.	from 56 strains of strictly anaerobic gram-negative rods isolated from stool and purulent lesions the fermentation products in the presence and absence of hemin were determined by quantitative gas-solid chromatography, using a simple and more rapid chromatographic procedure. with hemin the fermentation products were propionic, acetic, lactin and succinic acid. without hemin no or little succinic acid was formed and the main products were lactic and acetic acid. in both groups the distribution of ...	1978	655693
new medium for selection and presumptive identification of the bacteroides fragilis group.	a medium, bacteroides fragilis bile-esculin (bbe) agar, was designed for the selection and, presumptive identification of the b. fragilis group. bbe agar contains bile, esculin, ferric ammonium citrate, hemin, and gentamicin in a trypticase soy agar base. growth in the presence of 20% bile and esculin hydrolysis, detected by blackening of the medium, provide presumptive evidence for the identification of the b. fragilis group. in addition to stimulating the growth of many strains of the b. fragi ...	1978	659574
gas-lipuid chromatographic analysis of metabolic products in the identification of bacteroidaceae of clinical interest.	the acid end-products of 185 isolates from the family bacteroidaceae were separated and analysed by gas-liquid chromatography on broth cultures. different media were evaluated and definitive studies were performed in a fully supplemented complex medium. the limitations of this approach to the identification of a wide range of strains from various clinical sources were determined and the results were compared with those of a series of morphological, biochemical, tolerance and antibiotic-resistanc ...	1978	660640
bacteriologic culture results obtained before and after elective midtrimester urea abortion.	twenty patients undergoing elective midtrimester abortion by urea amnioinfusion had bacteriologic culture data obtained before and after the procedure. despite the presence of pathogens in the vagina and cervix prior to the procedure, only 20% of patients exhibited endometrial growth following abortion. factors that seem to favor such endometrial growth include increased injection-abortion intervals and the requirement for curettage to manage incomplete abortion.	1978	668370
[microbiological evaluation of cefoxitin, a new beta-lactamase resistant cephamycin antibiotic, compared to cephalothin, cephaloridine and cefazolin].	cefoxitin (mefoxitin), cephaloridin, cephalothin and cefazolin were tested in vitro against 380 clinical isolates of staph. aureus and enterobacteriaceae using the tube dilution procedure. of the gramnegative microorganisms a selection of 150 strains was examined regarding susceptibility to the antibiotic combinations cefoxitin/gentamicin and cefoxitin/sisomicin in comparison to cephalothin/gentamicin and cephalothin/sisomicin. cefoxitin has a broad antimicrobial spectrum and a high beta-lactama ...	1978	669547
the role of bacteroides fragilis in abscesses of the central nervous system: implications for therapy.		1978	670122
susceptibility of the bacteroides fragilis group of anaerobes to carbenicillin and ticarcillin.		1978	670123
[bacteroides fragilis bacteremias: clinical and evolutive features about 33 cases (author's transl)].	the frequency of non soil dwelling anaerobic infections is increasing. the authors report 33 cases of bacteroides fragilis bacteremias, and study the responsabilities of different factors of prognosis (especially age and underlying conditions). nitroimidazoles are very active against all bacteroides fragilis. this therapy is the drug of choice for such infections.	1978	673771
metronidazole treatment of liver abscess due to bacteroides fragilis.	a 67-year-old woman with a liver abscess due to bacteroides fragilis was treated with metronidazole 0.4 g orally every 8 h for 6 weeks. there was a rapid clinical improvement even though no surgical drainage was performed. by the indirect immunofluorescence technique using the patient's own strain as an antigen the antibody titer declined from 5120 to 80 in 6 months, suggesting eradication of the infecting agent.	1978	675165
[postoperative necrotizing enteritis with ristella septicemia. apropos of a case followed by recovery].		1978	677497
in vitro studies of piperacilin, a new semisynthetic penicillin.	piperacillin, a new semisynthetic penicillin, was compared with other semisynthetic penicillins, cephalosporins, and aminoglycosides by the agar dilution method against 3,600 isolates of facultative gram-negative bacilli, bacteroides fragilis, and enterococci. at 64 mug/ml, piperacillin inhibited 90% of the isolates in each group of organisms tested except for escherichia coli (83% inhibited by 64 mug/ml). compared with carbenicillin, piperacillin had a 16-fold increase in activity by weight aga ...	1978	677861
antibiotic therapy of endometritis following cesarean section. treatment successes and failures.	a prospective clinical and microbiologic study was carried out on 413 indigent patients undergoing cesarean section. operative site infection developed in 160 (38.5%). initial treatment with penicillin and kanamycin was successful in 125 of these 160 infections (78%). thirty-five patients (22%) failed to respond to penicillin and kanamycin and were treated with clindamycin or chloramphenicol. twenty-eight of the 35 responded promptly to the additional antibiotic therapy. the remaining 7 patients ...	1978	683627
bacteroides fragilis endocarditis, bacteremia and other infections treated with oral or intravenous metronidazole.		1978	686012
in vitro activity and beta-lactamase stability of bl-s786 compared with those of other cephalosporins.	in vitro activity of bl-s786, a new parenterally semisynthetic cephalosporin, was investigated against 570 bacterial isolates. bl-s786 inhibited most escherichia coli, klebsiella pneumoniae, proteus mirabilis, and salmonella. it inhibited some enterobacter and indole-positive proteus, but it was less active against these later species than was cefamandole, cefuroxime, or cefoxitin. it was not active against serratia marcescens, pseudomonas aeruginosa, or bacteroides fragilis. bl-s786 was the lea ...	1978	686701
veterans administration cooperative study on bowel preparation for elective colorectal operations: impact of oral antibiotic regimen on colonic flora, wound irrigation cultures and bacteriology of septic complications.	a ten hospital cooperative study comparing prophylactic oral neomycin and erythromycin base versus placebo demonstrated clinical efficacy of the antibiotics in preventing septic complications following elective colon operations. the present report concerns microbiological studies accomplished during this trial. cultures of colon contents during surgery showed the antibiotic prep reduced concentrations of both aerobes and anaerobes by approximately 10(5) bacteria/ml. virtually all major bacterial ...	1978	686893
in vitro activity of tiamulin (81.723 hfu), a new pleuromulin derivative, against clinically significant anaerobes.	the susceptibility of more than 40 strains of gram-negative and gram-positive anaerobes to tiamulin (sandoz 81.723 hfu), a new pleuromulin (pleuromutilin) derivative, was determined by broth dilution and agar dilution tests. the influences of density of the inoculum upon mics was studied by a specially designed pour plate-technique. bacteroides fragilis, b. vulgatus, b. splanchnicus, b. oralis, b. asaccharolyticus, b. melaninogenicus, fusobacterium fusiforme (f. nucleatum), sphaerophorus necroph ...	1978	690009
the bacteriology and chemotherapy of otogenic cerebral abscesses.		1978	690058
the distribution of bacteroides fragilis serotypes amongst clinical strains.	three hundred and twenty-two strains of bacteroides fragilis isolated from infected patients at three different hospitals were tested against 20 type specific b. fragilis antisera using the tube agglutination technique. of these strains 41.3% were assigned to a single o-serotype, a further 20.5% were agglutinated by several antisera and could not be classified and the remainder showed no reactions. three different serotypes were prevalent in the three hospitals and minor geographical variation w ...	1978	690426
the importance of c5 and the role of the alternative complement pathway in leukocyte chemotaxis induced in vivo and in vitro by bacteroides fragilis lipopolysaccharide.	chambers implanted subcutaneously in c5 normal (c5 n) and c5 deficient (c5 d) mice were used to examine the migration of polymorphonuclear leukocytes (pmns) into the wound chamber fluid in response to injected bacteroides fragilis lipopolysaccharide (lps). the difference in pmn migration was highly significant between the two mouse strains, the c5 d mice showing no initial, but a low, delayed migration. the results from the study indicated that chemotaxis plays a major role in the accumulation o ...	1978	696326
anaerobic and aerobic bacteriology in head and neck cancer surgery.	a prospective study of wound infections following major head and neck cancer surgery was undertaken to define a rational approach to trials of antibiotic prophylaxis and initial therapy of these infections. preoperative aerobic cultures were taken from the planned site of skin incision and from the oropharynx. both aerobic and anaerobic cultures were obtained from all wound infections. patients receiving prophylactic antibiotics were excluded from the study. the data indicate that preoperative c ...	1978	697638
participation of immunoglobulin and the alternative complement pathway in opsonization of bacteroides fragilis and bacteroides thetaiotaomicron.	studies were conducted to determine the requirements for immunoglobulin and complement for opsonization of bacteroides fragilis and bacteroides thetaiotaomicron. the ability of human sera depleted of immunoglobulin or complement components to promote phagocytosis and intracellular killing of the strains of bacteroides by human leukocytes was measured in vitro under anaerobic conditions. neither hypogammaglobulinemic sera nor pooled normal human serum (pnhs) heated at 56 c for 30 min supported ph ...	1978	701850
[asporogenic anaerobic bacterial cells isolated from extrahepatic abscesses and human breast tumor].		1978	704449
inactivation of metronidazole by anaerobic and aerobic bacteria.	the rate of inactivation of metronidazole in vitro was determined during the course of time-kill curves against anaerobic and aerobic bacteria in the stationary phase of growth. metronidazole at a concentration of 10 mug/ml, as measured by bioassay, was rapidly inactivated in broth culture by susceptible anaerobic bacteria (minimum bactericidal concentration </= 3 mug/ml), and this correlated closely with its bactericidal activity. in contrast, the drug was neither inactivated nor had any bacter ...	1978	708015
susceptibility of anaerobic bacteria to sulfamethoxazole/trimethoprim and routine susceptibility testing.	the minimal inhibitory concentrations (mics) of sulfamethoxazole and trimethoprim against 144 strains of obligately anaerobic bacteria were determined on diagnostic sensitivity test agar (oxoid) or in prereduced diagnostic sensitivity test broth, both supplemented with sodium pyruvate (1 mg/ml), hemin (5 mug/ml), and vitamin k(1) (1 mug/ml). fifty-eight percent of the strains were susceptible to sulfamethoxazole alone (mic </= 16 mug/ml), only 12% were susceptible to trimethoprim alone (mic </= ...	1978	708016
bacteroides fragilis meningitis in a neonate successfully treated with metronidazole.		1978	712483
effects of beta-endorphin on narcotic abstinence syndrome in man.		1978	351136
active immunization of female rats with luteinizing hormone releasing hormone (lhrh).		1978	352412
septic induced acute gastric erosions: the role of cimetidine.		1978	417217
colonization resistance against potentially pathogenic bacteria in hexaflora-associated gnotobiotic mice.	a study of colonization resistance against potentially pathogenic bacteria (escherichia coli and pseudomonas aeruginosa) was conducted in hexaflora-associated gnotobiotic mice. groups of germfree akr mice were swabbed with five bacterial and a single gastrointestinal yeast species: streptococcus faecalis. lactobacillus brevis. staphylococcus epidermidis, enterobacter aerogenes, bacteroides fragilis var. vulgatus, and torulopsis sp. all species became established in the gut in 8 weeks. later thes ...	1978	417787
microflora of the cervix during normal labor and the puerperium.	the normal flora of the cervix was studied in 50 healthy women in labor and on the third day postpartum. aerobic bacteria were the exclusvie isolates in 25% of these women, and 75% had anaerobic bacteria in addition to aerobes. anaerobes were always found in association with aerobes. the most frequent isolate of bacteroides was bacteroides melaninogenicus, found in 20% of the women during labor and 14% during the puerperium. bacteroides fragilis was distinctly absent during labor but was found i ...	1978	351071
bacteriologic culture results obtained before and after elective midtrimester urea abortion.	twenty patients undergoing elective midtrimester abortion by urea amnioinfusion had bacteriologic culture data obtained before and after the procedure. despite the presence of pathogens in the vagina and cervix prior to the procedure, only 20% of patients exhibited endometrial growth following abortion. factors that seem to favor such endometrial growth include increased injection-abortion intervals and the requirement for curettage to manage incomplete abortion.	1978	363343
metabolism of 2-deoxy-2-fluoro-d-[3h]glucose and 2-deoxy-2-fluoro-d-[3h]mannose in yeast and chick-embryo cells.	2-deoxy-2-fluoro-d-[3h]glucose and 2-deoxy-2-fluoro-d-[3h]mannose have been prepared by tritiation of the corresponding unlabeled 2-fluoro sugars. the tritiated 2-fluoro sugars are phosphorylated and activated by utp and by gtp to yield udp-2-deoxy-2-fluoro-d-[3h]glucose, udp-2-deoxy-2-fluoro-d-[3h]mannose, gdp-2-deoxy-2-fluoro-d-[3h]glucose and gdp-2-deoxy-2-fluoro-d-[3h]mannose in both cell types. the nucleotide derivatives could also be labeled in the nucleotide moiety by feeding the cells wi ...	1978	352691
localization of luteinizing hormone (lh) and testosterone (t) or dihydrotestosterone (dht) in the gonadotropic cells of the anterior pituitary by using ultra-cryomicrotomy and immunocytochemistry.		1978	352889
nonspecific immunostimulant activities of synthetic trehalose-6,6'-diesters (lower homologs of cord factor).	mycobacterial cord factors (6,6'-diesters of trehalose with mycolic acids ranging from c80 to c90) have been shown to protect mice effectively against infection with klebsiella pneumoniae or with listeria monocytogenes. our present findings indicate that the low-molecular-weight cord factor of corynebacterium diphtheriae (with corynomycolic acids ranging from c28 pto c36) is equally active. moreover, its synthetic analog (with synthetic c32 mycolic acid) has the same activity. two lower syntheti ...	1978	352926
ribosomal proteins l7/l12 localized at a single region of the large subunit by immune electron microscopy.		1978	368343
effects of storage in an anaerobic transport system on bacteria in known polymicrobial mixtures and in clinical specimens.	an anaerobic transport system (ats) which provides for catalytic removal of oxygen was evaluated by using in vitro-prepared polymicrobial mixtures of logphase bacteria and clinical specimens. inoculated swabs were stored at room temperature in (i) aerobic, (ii) anaerobic glove box, and (iii) ats environments, and bacteria were quantitated after 2, 24, 48, and 72 h. bacteria in a three-part mixture of bacteroides fragilis, peptostreptococcus anaerobius, and escherichia coli and in a five-part mix ...	1978	370142
simple method for detection of penicillinase-producing neisseria gonorrhoeae.	a simple, reliable, and economical method for detection of penicillinase-producing neisseria gonorrhoeae using a penicillin disk and a penicillin-sensitive organism is described.	1978	415067
surgical treatment of valvular heart disease.		1978	415632