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[clinical use of the trh-tsh stimulation test with special reference to pediatric thyroid-gland diseases]. 199996623
chunking in recall of symbolic drawings. 199988658
minoxidil in resistant hypertension.minoxidil in combination with propranolol and diuretics controlled the blood-pressure in a group of hypertensive patients who were resistant to treatment with large doses of standard drugs. the main problem was fluid retention but subjective side-effects were fewer than in a comparable group on other drugs.199995728
intensive care and the very low birthweight infant. 199989424
rats of the genus rattus are reservoir hosts for pathogenic bartonella species: an old world origin for a new world disease?bartonella species were isolated from the blood of 63 of 325 rattus norvegicus and 11 of 92 rattus rattus from 13 sites in the united states and portugal. infection in both rattus species ranged from 0% (e.g., 0/87) to approximately 60% (e.g., 35/62). a 337-bp fragment of the citrate synthase (glta) gene amplified by polymerase chain reaction was sequenced from all 74 isolates. isolates from r. norvegicus were most similar to bartonella elizabethae, isolated previously from a patient with endoca ...199910353885
[indications for relief and palliative operations].torkildsen and spitz-holter drainages and/or osteoclastic trepanation were performed on 29 patients suffering from a severe increase in intracranial pressure and/or a severely worsened general condition as a relieving intervention in order to permit a tumor operation later. the relieving measure enabled a tumor operation in 28 patients. the same procedure was used as a palliative step for another group of 73 patients suffering from inoperable tumorous processes. evaluation in these cases showed ...199995657
chemotherapy of head and neck cancer: combination treatment with cyclophosphamide, adriamycin, methotrexate, and bleomycin.a combination of cyclophosphamide, adriamycin, methotrexate, and bleomycin (camb) was explored in patients with advanced, nonresectable epidermoid carcinoma from primary sites in the head and neck, recurrent or persistent after radiation or surgery. objective regression (greater than 50%) of measurable tumor was present in 35% of the patients. the median duration of response was 2.5 months. median survival of responders was slightly less than the nonresponders, but the difference was not signifi ...199985249
an experimental study on the effect of plasma expanders on blood coagulability.the effect of various plasma expanders on blood coagulation was studied using the thromboelastography (teg). solutions of 5, 10, 20, and 50% concentration of each expander (6% low molecular weight hydroxyethyl-starch (6% hespander), 3% dextran-40, 6% high molecular weight hydroxyethyl-starch (6 hes), and 6% dextran-70) or solvent (lactated ringer solution and normal saline) in blood were prepared and their coagulability was examined by teg. in the low molecular weight plasma expanders (6% hespan ...199985502
bartonella infections: diagnostic and management issues.bartonella species are emerging pathogens. renewed interest in this group of bacteria has been highlighted by the recent description of new species, which are pathogenic for humans (bartonella elizabethae and bartonella clarridgeae), and their association with an increasing number of clinical manifestations, the more prevalent being cat scratch disease, bacillary angiomatosis, and culture-negative endocarditis.199817033388
bartonella tribocorum sp. nov., a new bartonella species isolated from the blood of wild rats.two bartonella strains from blood of two wild rats (rattus norvegicus) living in a rural environment were isolated. these strains were distinct from all previously known bartonella species based on phenotypic and genotypic characteristics. this new species is distinguished by its trypsin-like activity, the absence of the ability to hydrolyse proline and tributyrin, its 16s rrna and citrate synthase gene sequences and by whole-dna hybridization data. this new species, for which the name bartonell ...19989828434
leber's neuroretinitis in a patient with serologic evidence of bartonella elizabethae. 19989654422
comparison of partial citrate synthase gene (glta) sequences for phylogenetic analysis of bartonella species.nucleotide base sequence data were obtained for a 940-bp fragment of the citrate synthase-encoding gene (glta) of representatives of the eight validly described bartonella species and seven uncharacterized bartonella strains obtained from small mammals. complete 16s rrna gene sequences were also determined for the uncharacterized strains, and these sequences revealed that each strain had a unique sequence which was very similar to the sequences of the previously recognized bartonella species. a ...19968863415
antibodies to bartonella species in inner-city intravenous drug users in baltimore, md.bartonella quintana has recently been associated with homeless alcoholic men. both b quintana and bartonella henselae have been shown to be opportunistic pathogens of people with acquired immunodeficiency syndrome. the reservoirs and modes of transmission of these infections are incompletely known.19968944742
[cat-scratch disease and disease caused by bartonella (rochalimaea)].the aetiology of cat scratch disease remains controversial since both afipia felis and bartonella (rochalimaea) henselae have been isolated from diseased lymph nodes. bartonella henselae, bartonella (rochalimaea) quintana and bartonella (rochalimaea) elizabethae cause endocarditis and bartonella bacilliformis cause septicemia (oroya's fever) in non-immunocompromized patients, and bartonella henselae and bartonella quintana cause fever, bacillary angiomatosis, and visceral peliosis in human immun ...19957534931
use of bartonella antigens for serologic diagnosis of cat-scratch disease at a national referral center.bartonella henselae (formerly the genus rochalimaea) has recently been isolated from patients with cat-scratch disease and their cats, and since september 1992 the centers for disease control and prevention has offered an indirect fluorescent antibody assay for bartonella-specific antibody.19957542443
proposals to unify the genera bartonella and rochalimaea, with descriptions of bartonella quintana comb. nov., bartonella vinsonii comb. nov., bartonella henselae comb. nov., and bartonella elizabethae comb. nov., and to remove the family bartonellaceae from the order rickettsiales.dna hybridization data (hydroxyapatite method, 50 to 70 degrees c) indicate that rickettsia prowazekii, the type species of the type genus of the family rickettsiaceae, is substantially less closely related to rochalimaea species than was previously thought. the levels of relatedness of rickettsia prowazekii to rochalimaea species and to bartonella bacilliformis under optimal conditions for dna reassociation were 0 to 14%, with 25.5% or greater divergence in related sequences. when stringent rea ...19938240958
rochalimaea elizabethae sp. nov. isolated from a patient with endocarditis.a rochalimaea-like organism (strain f9251) was isolated from a patient with endocarditis after blood drawn for culture before antimicrobial therapy was subcultured onto blood and chocolate agars and incubated for 2 weeks in 5% co2. the strain was phenotypically similar to known rochalimaea species. the cellular fatty acid composition of strain f9251 was close to but distinct from those of the three known rochalimaea species and was most similar to that of r. vinsonii. labeled dna from strain f92 ...19937681847
structure of the human centromere at metaphase.until recently the centromere was thought to be a relatively homogeneous region of densely packed heterochromatin with a single differentiated domain--the kinetochore--at its surface, representing the point of attachment of the mitotic spindle. we now know that the centromere of higher eukaryotes is composed of several domains that have been identified using antibody probes. somewhere within the domains are located both the factor(s) that control the disjunction of sister chromatids and the mole ...19902193435
air sampling for legionella. 19902232037
modification of allergen-induced airway obstruction and airway hyperresponsiveness in an allergic rabbit model by the selective platelet-activating factor antagonist, bn 52021.allergen challenge of eight ragweed-immunized rabbits elicited a prolonged airway obstruction that was evident during the 6-hour study period. airway responsiveness to histamine was enhanced 24 hours after allergen exposure (geometric mean of the 50% reduction in effective dose [ed50] of dynamic compliance [cdyn] before challenge, 3.46 mg/ml, decreased to 0.52 mg/ml after challenge, p less than 0.01; pulmonary resistance ed50 geometric mean before challenge, 3.50 mg/ml, decreased to 0.65 mg/ml a ...19892600327
[experimental study on the changes of bile acids and their fractions after liver ischemia].serum bile acids and their fractions in the systemic and portal vein were measured after liver ischemia of 0, 30, 60, and 90 minutes with extracorporeal venous bypass in 20 dogs. the following results were obtained: 1) total concentration of bile acids in the serum rapidly increased during the ischemic phase because of extinction of enterohepatic circulation due to flow of portal blood into the systemic circulation. 2) portal blood flow decreased after recirculation of the liver, and this decrea ...19892811841
[tumor metastasis and growth factors].massive investigations are being carried out on growth factors. growth factors are an important determinant for the formation of successive tumor metastasis at target organs. we review the findings, including our data, of growth factors in relation to tumor metastasis.19892679395
estrogenic control of spermidine/spermine n1-acetyltransferase activity in rat uterus. 19883076330
high mutagenic activity of 3-azido-1,2-propanediol (azidoglycerol, ag) in strain d7 of saccharomyces cerevisiae.3-azido-1,2-propanediol (azidoglycerol, ag) showed a high mutagenicity in strain d7 of saccharomyces cerevisiae. at 5 mm it increased the spontaneous frequency of isoleucine revertants 3500 times and the frequency of gene convertants 3000 times during 24 h of growth, reducing the growth rate to 30%. in non-growth conditions, treatment with 150 mm of ag for 3 h reduced cell survival to 60% and enhanced the frequency of isoleucine revertants 490 times and tryptophan-independent convertants 50 time ...19873553915
radiometric-high-performance liquid chromatographic assay for nicotine and twelve of its metabolites.a sensitive, reproducible radiometric-high-performance liquid chromatographic assay has been developed to measure concentrations of nicotine and twelve of its metabolites in biological fluids. following administration of nicotine ([2-14c]pyrrolidine) to rats, the assay was used in a pharmacokinetic investigation.19873667778
effects of noise on pure-tone thresholds in blackbirds (agelaius phoeniceus and molothrus ater) and pigeons (columba livia).blackbirds and pigeons were trained to detect tones in quiet and in broadband noise by using positive-reinforcement techniques. in experiment 1, thresholds in noise were obtained in blackbirds as a function of both tone frequency and noise intensity for a pulsed noise masker (noise gated on and off with tone). for blackbirds, critical ratios (the ratio of the power of the just-detectable tone in noise to the power of the noise masker) obtained in pulsed noise showed no consistent relation to ton ...19873568604
plasmodium falciparum malaria: band 3 as a possible receptor during invasion of human erythrocytes.human erythrocyte band 3, a major membrane-spanning protein, was purified and incorporated into liposomes. these liposomes, at nanomolar concentrations of protein, inhibited invasion of human erythrocytes in vitro by the malaria parasite plasmodium falciparum. liposomes containing human band 3 were ten times more effective in inhibiting invasion than those with pig band 3 and six times more effective than liposomes containing human erythrocyte glycophorin. liposomes alone or liposomes containing ...19853880920
the temporal evolution of hypoglycemic brain damage. i. light- and electron-microscopic findings in the rat cerebral cortex.in the course of a study on the pathogenesis of neuronal necrosis in severe hypoglycemia, the morphological characteristics reflecting reversible and irreversible neuronal lesions were examined as a function of time following normalization of blood glucose. to that end, closely spaced time intervals were studied in the rat cerebral cortex before, during, and up to 1 year after standardized pure hypoglycemic insults of 30 and 60 min of cerebral isoelectricity. both the superficial and deep layers ...19854024866
[distribution of antibodies against the human t-cell leukemia virus in healthy venezuelan adults]. 19853008469
administration of thyrotropin releasing hormone (trh) to rats releases dopamine in n. accumbens but not n. caudatus. 1979105304
[relationship of the structure of specific somatic antigen polysaccharides in shigella dysenteriae bacteriae to the immunochemical properties]. 197985516
preganglionic neurons in the sacral spinal cord of the rat: an hrp study. 197986176
immunologic studies of native and modified human factor viii/von willebrand factor.factor viii/von willebrand factor (fviii/vwf) is a glycoprotein with a molecular weight greater than one-million daltons. two activities are associated with this large molecule: fviii procoagulant activity and vwf activity. incubation of fviii/vwf with proteolytic enzymes causes rapid inactivation of the fviii procoagulant activity but has little effect on the vwf activity or antigenicity. in an attempt to gain insight into the structural features required for these two activities, antisera were ...197988237
hippocampal evoked potentials and eeg changes during classical conditioning in the rat.hippocampal evoked potentials (eps) and eeg responses were studied in rats, using a classical conditioning paradigm (water, us), with a spatially discontiguous cs-us arrangement in order to separate the cs and goal-related responses. in early training, when the orienting score was high, the tone cs, instead of eliciting a definite ep, usually reset hippocampal theta activity in phase, i.e. theta rhythm became time-locked to cs. with further training, orienting activity (ori) decreased to the pre ...197988362
[effect of aflatoxin b 1 on respiration and oxidative phosphorylation in the rabbit. ii. research on cardiac and renal mitochondria].the effect of various concentrations of aflatoxin b1 (ab1) is studied "in vitro" on heart (hm) and kidney mitochondria of rabbit (km). ab1 inhibits (4 x 10(-4)m) the respiratory rate up to a maximum 50-35% in hm and 28-35% in km by glutamate and succinate as substrates respectively, but it does not uncouple oxidative phosphorylation nor does it inhibit site iii (ascorbate + tmpd). the inhibited site appears to be between cytochromes b and c (c1). ab1 seems to be easily transported across heart m ...1979548060
[role of anti-brain antibodies in the development of mineralocorticoid deficiency]. 197985292
effects of althesin and its steroidal components on a variety of excised smooth muscle preparations. 1979262472
[the adrenergic innervation of the thoracic lymphatic duct in dogs in postnatal ontogeny].using histochemical fluorescence technique, studies have been made on the adrenergic innervation of the wall of the thoracal lymphatic duct in postnatal development of puppies. adrenergic fibers were found in the adventitial layer of the duct. during postnatal development of the animals, adrenergic innervation of this duct becomes more perfect, reaching the level of adult animals to the age of 2-3 months.197995857
[the lice of the gerbils of tajikistan].2606 gerbils of four species from tajikistan were examined. on them there were found over 14 thousand sucking lice of 10 species, four of which are typical to gerbils. hoplopleura merionidis ferris is a mongolian-turkestan species, which in central asia parasitizes meriones meridianus pallas and m. unguiculatus milne-edw. and in middle asia--m. meridianus and m. erythrourus gray, seldom m. tamariscinus pallas. polyplax chinensis ferris, a parasite of m. meridianus, is a mongolian-turkestan speci ...197995816
deficiency of the ninth component of complement in man.the studies of serum from a case with c9 (the ninth component of complement) deficiency are described. a 29-year-old woman in good health was found to have low serum complement levels (ch50). c9 of her serum was undetectable by the hemolytic assay and by the immunochemical analysis but all other components were normal. it was demonstrated that low ch50 of her serum was due to the hemolysis of the sensitized sheep erythrocytes (ea) by the complement components from c1 to c8.197995812
potentiating effect of nitrate and other anions on contraction in vascular smooth muscle. 197887173
naturally occurring diatomaceous pneumoconiosis in sub-human primates. 197896157
steroid production by quartered and capsular rat adrenal gland in response to haemorrhage.60 min after rapid bleeding (1.5--2.0 per cent of b. w.) both aldosterone and corticosterone production rate by quartered rat adrenals were found to be elevated. however, no difference was observed in the rate of aldosterone and corticosterone production by capsular adrenals of sham operated and hypovolaemic rats. corticosterone production rate by decapsulated adrenals was much more higher after haemorrhage than in the control group. the same alterations could be observed incubating adrenal tiss ...1975179800
gonococcal conjunctivitis. 19744205793
formation of lithogenic bile in man. 19734362764
characterization of phospholipase b of culex pipiens fatigans.phospholipase b has been found in the mosquito culex pipiens fatigans, and some of its properties have been studied. the enzyme had a high optimum temperature (45 degrees c) and broad alkaline ph optimum (8-9). it was inactive toward diacylphospholipids, and hydrolyzed lysolecithin at a higher rate than lysophosphatidyl ethanolamine. the enzyme was heat labile, but lysolecithin protected it against heat inactivation. phosphatidyl ethanolamine, phosphatidyl choline, deoxycholate, fe(+++), and hg( ...19694390654
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