Publications

TitleAbstractYear(sorted descending)
Filter
PMID
Filter
elucidating transmission dynamics and host-parasite-vector relationships for rodent-borne bartonella spp. in madagascar.bartonella spp. are erythrocytic bacteria transmitted via arthropod vectors, which infect a broad range of vertebrate hosts, including humans. we investigated transmission dynamics and host-parasite-vector relationships for potentially zoonotic bartonella spp. in invasive rattus rattus hosts and associated arthropod ectoparasites in madagascar. we identified five distinct species of bartonella (b. elizabethae 1, b. elizabethae 2, b. phoceensis 1, b. rattimassiliensis 1, and b. tribocorum 1) infe ...201728351673
bartonella in rodents and ectoparasites in the canary islands, spain: new insights into host-vector-pathogen relationships.bartonella genus is comprised of several species of zoonotic relevance and rodents are reservoirs for some of these bartonella species. as there were no data about the range of bartonella species circulating among rodents in the canary islands, our main aim was to overcome this lack of knowledge by targeting both the citrate synthase (glta) and the rna polymerase beta subunit (rpob) genes. a total of 181 small mammals and 154 ectoparasites were obtained in three of the canary islands, namely ten ...201728660292
infection rates of wolbachia sp. and bartonella sp. in different populations of fleas.in the present study, a molecular detection of bartonella sp. and wolbachia sp. in ctenocephalides felis (siphonaptera: pulicidae) isolated from canis lupus familiaris from different geographical areas of spain, iran and south africa, and in stenoponia tripectinata tripectinata isolated from mus musculus from the canary islands has been carried out by amplification of the 16s ribosomal rna partial gene of wolbachia sp. and intergenic spacer region (its region) of bartonella sp. a total of 70 % o ...201627515668
prevalence and diversity of bartonella species in rodents from georgia (caucasus).bartonella infections are widespread and highly prevalent in rodents. several rodent-associated bartonella species have been related to human diseases. recently, bartonella species was reported as the etiology of a human case in the country of georgia (caucasus). however, information on bartonella in rodents in georgia is absent. rodent hearts were collected from georgia to investigate the presence and diversity of bartonella species. bartonella bacteria were cultured from 37.2% (16/43) of roden ...201627162268
zoonotic and vector-borne infections among urban homeless and marginalized people in the united states and europe, 1990-2014.in high-income countries, homeless individuals in urban areas often live in crowded conditions with limited sanitation and personal hygiene. the environment of homelessness in high-income countries may result in intensified exposure to ectoparasites and urban wildlife, which can transmit infections. to date, there have been no systematic evaluations of the published literature to assess vector-borne and zoonotic disease risk to these populations.201627159039
bartonella spp. in small mammals, benin.this study aimed to investigate the prevalence and genetic diversity of bartonella organisms in small mammals in cotonou, benin. we captured 163 rodents and 12 insectivores and successfully detected bartonella dna from 13 of the 175 small mammal individuals. bartonella spp., identical or closely related to bartonella elizabethae, bartonella tribocorum, and bartonella rochalimae, was detected. a potential new bartonella species, proposed as candidatus bartonella mastomydis, was found in three mas ...201626910412
whole-genome sequence analysis and exploration of the zoonotic potential of a rat-borne bartonella elizabethae.bartonella elizabethae has been known to cause endocarditis and neuroretinitis in humans. the genomic features and virulence profiles of a b. elizabethae strain (designated as beum) isolated from the spleen of a wild rat in kuala lumpur, malaysia are described in this study. the beum strain has a genome size of 1,932,479bp and gc content of 38.3%. there is a high degree of conservation between the genomes of strain beum with b. elizabethae type strains (atcc 49927 and f9251) and a rat-borne stra ...201626658020
blood and plasma ascorbic acid in indian childhood cirrhosis. 20164784731
bartonella, rodents, fleas and ticks: a molecular field study on host-vector-pathogen associations in saxony, eastern germany.bartonellae cause zoonotic diseases and are transmitted by arthropods. rodents are reservoirs for most bartonella spp. as the knowledge about bartonella in rodents and their parasitizing ectoparasites is scarce in germany, this study's objectives were to investigate bartonella spp. in small mammals and in their ectoparasites. a total of 79 small mammals (seven species) were captured and their ectoparasites collected at seven sites around leipzig, saxony, germany, in 2010 and 2011. altogether, 79 ...201627220973
the distribution and diversity of bartonella species in rodents and their ectoparasites across thailand.our study highlights the surveillance of bartonella species among rodents and their associated ectoparasites (ticks, fleas, lice, and mites) in several regions across thailand. a total of 619 rodents and 554 pooled ectoparasites (287 mite pools, 62 flea pools, 35 louse pools, and 170 tick pools) were collected from 8 provinces within 4 regions of thailand. bandicota indica (279), rattus rattus (163), and r. exulans (96) were the most prevalent species of rats collected in this study. real-time p ...201526484537
[use of l-asparaginase in therapy with special reference to acute lymphatic leukemia]. 20154502507
[uterine metastasis from a colloid epithelioma of the appendix]. 20154350561
preliminary survey of ectoparasites and associated pathogens from norway rats in new york city.the norway rat (rattus norvegicus) is a reservoir of many zoonotic pathogens and lives in close proximity to humans in urban environments. human infection with rodent-borne disease occurs either directly through contact with a rat or its excreta, or indirectly via arthropod vectors such as fleas and ticks. here, we report on the diversity and abundance of ectoparasitic arthropod species and associated pathogenic bacteria from 133 norway rats trapped over a 10-mo period in manhattan, new york, ny ...201526336309
molecular detection of zoonotic bartonellae (b. henselae, b. elizabethae and b. rochalimae) in fleas collected from dogs in israel.fleas represent an acknowledged burden on dogs worldwide. the characterization of flea species infesting kennel dogs from two localities in israel (rehovot and jerusalem) and their molecular screening for bartonella species (rhizobiales: bartonellaceae) was investigated. a total of 355 fleas were collected from 107 dogs. the fleas were morphologically classified and molecularly screened targeting the bartonella 16s-23s internal transcribed spacer (its). of the 107 dogs examined, 80 (74.8%) were ...201525865162
changes in renal size following intra-arterial administration of water-soluble contrast medium. 20154430589
are tranquilizers used as "chemical strait-jackets"? do adequate safeguards exist? 20154481720
editorial: carotid endarterectomy and t.i.a. 20144128839
comparison of two statistical techniques for the surveillance of birth defects through a monte carlo simulation. 20143961319
injury to the glenoid fossa.an illustrated case of fracture through the confines of the glenoid fossa by the mandibular condyle is presented. the mechanism of injury and postinjury sequelae of this rarely reported but frequently suspected occurrence are discussed and a treatment rationale proposed. the key to the diagnosis of this entity is an awareness of vector forces directed to the region of the glenoid fossa with or without evidence of subcondylar fracture.20143945692
bartonella species in invasive rats and indigenous rodents from uganda.the presence of bartonellae in invasive rats (rattus rattus) and indigenous rodents (arvicanthis niloticus and cricetomys gambianus) from two districts in uganda, arua and zombo, was examined by pcr detection and culture. blood from a total of 228 r. rattus, 31 a. niloticus, and 5 c. gambianus was screened using genus-specific primers targeting the 16s-23s intergenic spacer region. furthermore, rodent blood was plated on brain heart infusion blood agar, and isolates were verified as bartonella s ...201424575846
high prevalence of rickettsia typhi and bartonella species in rats and fleas, kisangani, democratic republic of the congo.the prevalence and identity of rickettsia and bartonella in urban rat and flea populations were evaluated in kisangani, democratic republic of the congo (drc) by molecular tools. an overall prevalence of 17% bartonella species and 13% rickettsia typhi, the agent of murine typhus, was found in the cosmopolitan rat species, rattus rattus and rattus norvegicus that were infested by a majority of xenopsylla cheopis fleas. bartonella queenslandensis, bartonella elizabethae, and three bartonella genot ...201424445202
histogenesis of malignant melanoma with an adjacent component of the superficial spreading type.there has been a world-wide exponential increase in the incidence of thin malignant melanoma. at the sydney melanoma unit, the proportion of patients diagnosed as having superficial spreading melanoma has more than doubled from 33% prior to 1960 to 78% during 1980-83. a study was made of the non-invasive component of malignant melanoma with an adjacent non-invasive component of the superficial spreading type in an attempt to elucidate the pathogenetic mechanisms involved in these changing trends ...20144047726
bartonella species in fleas from palestinian territories: prevalence and genetic diversity.bartonellosis is an infectious bacterial disease. the prevalence and genetic characteristics of bartonella spp. in fleas of wild and domestic animals from palestinian territories are described. flea samples (n=289) were collected from 121 cats, 135 dogs, 26 hyraxes and seven rats from northern (n=165), central (n=113), and southern palestinian territories (n=11). the prevalent flea species were: ctenocephalides felis (n=119/289; 41.2%), ctenocephalides canis (n=159/289; 55%), and xenopsylla sp. ...201425424254
design and data quality of a mixed longitudinal study to elucidate the role of dietary calcium and phosphorus on bone mineralization in pre-, peri-, and postmenopausal women.the study design and data quality control of an ongoing study (10 yr duration) in a few hundred women are presented. good variables with respect to their longitudinal usefulness are: body weight, body height, and span-width. reasonable variables are the bone parameters of the radius (bmc, bw, and bmc/bw). poor variables are: dietary calcium and phosphorus intake, dietary calcium-to-phosphorus ratio, urinary calcium-to-creatinine ratio, urinary sodium-to-creatinine ratio, hematocrit, serum alkali ...20143962907
diagnosis of carrion's disease by direct blood pcr in thin blood smear negative samples.bartonella bacilliformis is the etiologic agent of carrion's disease. this disease has two well established phases, the most relevant being the so called oroya fever, in which b. bacilliformis infect the erythrocytes resulting in severe anemia and transient immunosuppression, with a high lethality in the absence of adequate antibiotic treatment. the presence of b. bacilliformis was studied in 113 blood samples suspected of carrion's disease based on clinical criteria, despite the absence of a po ...201424651298
prevalence and diversity of bartonella species in commensal rodents and ectoparasites from nigeria, west africa.bartonellae are fastidious bacteria causing persistent bacteremia in humans and a wide variety of animals. in recent years there is an increasing interest in mammalian bartonelloses in general and in rodent bartonelloses in particular. to date, no studies investigating the presence of bartonella spp. in rodents and ectoparasites from nigeria were carried out.201323738028
bartonella prevalence and genetic diversity in small mammals from ethiopia.more than 500 small mammals were trapped at 3 localities in northern ethiopia to investigate bartonella infection prevalence and the genetic diversity of the bartonella spp. we extracted total dna from liver samples and performed pcr using the primers 1400f and 2300r targeting 852 bp of the bartonella rna polymerase beta subunit (rpob) gene. we used a generalized linear mixed model to relate the probability of bartonella infection to species, season, locality, habitat, sex, sexual condition, wei ...201323421888
transmission dynamics of bartonella sp. strain oe 1-1 in sundevall's jirds (meriones crassus).a high prevalence of bartonella infection is found in many natural systems; however, the transmission dynamics leading to observations of these infections is not fully understood. the capability of xenopsylla ramesis fleas to serve as competent vectors of bartonella sp. oe 1-1 (a strain closely related to the zoonotic bartonella elizabethae) to meriones crassus jirds was investigated. naïve x. ramesis fleas were placed for 72 h on naïve jirds or jirds that were either experimentally or naturally ...201323241972
findings with cis-z-clopenthixol in the treatment of acute mania and schizophrenia.the authors report the results of an open clinical trial with cis(z)-clopenthixol (cisordinol), the isolated cis-isomer of the clopenthixol racemate (sordinol). the drug was applied to 18 patients with severe forms of manic or schizophrenic disease, diagnosed according to icd 9. the compound was applied intravenously or orally, daily doses ranging from 10-160 mg. for the duration of the study (6 weeks) the patients were repeatedly rated with the cgi, bprs or imps (abbreviated version), and sever ...20133797470
assessment of a bubble tonometer as a quality control system for blood gas analyzers (po2 and pco2).a blood gas tonometer device, comprising an accurate gas mixer (corning 192) associated with a dual channel bubble tonometer (corning 184) was tested for reliability, accuracy and ease of use as a quality control system for po2 and pco2 blood gas analyzers. from our results it is apparent that this system can be used instead of older and more bulky tonometry devices, gas mixing systems or cylinders of fixed composition.20133889784
hypercalcemia and acute renal insufficiency in a 24-year-old white male with lung disease. 20133754694
plasma exchange for failure of early resuscitation in thermal injuries. 20133648044
comparative efficacy of calcium antagonist drugs in the prophylaxis of migraine. 20133908401
identification of diverse bartonella genotypes among small mammals from democratic republic of congo and tanzania.small mammals from the democratic republic (dr) of the congo and tanzania were tested to determine the prevalence and genetic diversity of bartonella species. the presence of bartonella dna was assessed in spleen samples of the animals by rpob- and glta-polymerase chain reactions (pcrs). by rpob-pcr, bartonella was detected in 8 of 59 animals of dr congo and in 16 of 39 tanzanian animals. by glta-pcr, bartonella was detected in 5 and 15 animals of dr congo and tanzania, respectively. the gene se ...201222855765
reflections from a decade of carotid reconstructive surgery.carotid artery reconstructive surgery for atherosclerotic lesions of the extracranial cerebral circulation has become the most common operation in peripheral vascular surgery. a better understanding of the indications for operative intervention, enhanced monitoring during surgery, and more precise management of intraoperative anesthesia have all helped decrease the risks associated with internal carotid endarterectomy. to evaluate the safety and efficacy of extracranial carotid reconstructive su ...20123358162
bartonella bacteria in nature: where does population variability end and a species start?the application of new molecular approaches has permitted the differentiation of numerous strains belonging to the genus bartonella and identification of new bartonella species. however, the molecular typing of these organisms should be coupled with studies aimed at defining the biological properties of the newly described species. the long-history of co-adaptation between bartonella(1) bacteria and their mammalian hosts and possibly arthropod vectors provides a unique opportunity for applying t ...201222449771
vulvovaginal reconstruction following radical resections. 20123757340
experimental infection of three laboratory mouse stocks with a shrew origin bartonella elizabethae strain: an evaluation of bacterial host switching potential.bartonella elizabethae has been reported as a causative agent of human illnesses and strains of this bacterium are commonly isolated from commensal small mammals in asia.201222957127
prolonged control of increased intracranial pressure with glycerin. 20125049685
rural hospitals rely more on outpatient revenue. 20123391547
mallet fractures.contrary to our observations, reports in the literature maintain that only a third of mallet finger deformities are caused by intra-articular fractures of the posterior margin of the distal phalanx. as functional impairment sometimes remains after treatment, there is still much discussion as to the relative merits of conservative and surgical management of this lesion. this article presents 21 cases of mallet finger deformities with fracture of the distal phalanx, of which 17 received surgical t ...20123426323
basal metabolism of obese adolescents: inconsistent diet and exercise effects.effects of 20 wk of diet-plus-behavior (db) therapy or exercise-plus-diet-plus-behavior (edb) therapy on changes in basal energy expenditure (bee) were studied in 36 obese male and female adolescents. bee was assessed by open-circuit spirometry and body composition by hydrostatic weighing. dietary restriction was based on the dietary-exchange program. behavioral treatment included record-keeping, stimulus-control, and reinforcement techniques. edb therapy included 50 min/d, 3 d/wk of aerobics. a ...20123414571
human seroreactivity against bartonella species in the democratic republic of congo.to assess the presence and identity of bartonella species in a pool of human blood samples from drc congo.201121771478
identification of novel bartonella spp. in bats and evidence of asian gray shrew as a new potential reservoir of bartonella.many studies indicated that small mammals are important reservoirs for bartonella species. using molecular methods, several studies have documented that bats could harbor bartonella. this study was conducted to investigate the relationship of bartonella spp. identified in bats and small mammals living in the same ecological environment. during may 2009 and march 2010, a total of 102 blood specimens were collected. by whole blood culture and molecular identification, a total of 6 bats, 1 rodent a ...201122005177
bartonellae of the namaqua rock mouse, micaelamys namaquensis (rodentia: muridae) from south africa.the aim of this study was to determine bartonella prevalence and diversity in namaqua rock mice, micaelamys namaquensis, a species endemic to south africa, which can attain pest status. a total of 100 heart samples collected monthly from march to december were screened for bartonella genome presence using three primer sets targeting the citrate synthase (glta) gene, the nadh dehydrogenase gamma subunit (nuog) gene and the rna polymerase β-subunit-encoding gene (rpob). an overall prevalence of 44 ...201122204791
a multi-gene analysis of diversity of bartonella detected in fleas from algeria.we report the molecular detection of several bartonella species in 44 (21.5%) of 204 fleas from algeria collected from 26 rodents and 7 hedgehogs. bartonella elizabethae and b. clarridgeiae were detected in the fleas collected on hedgehogs. bartonella tribocorum and b. elizabethae were detected in fleas collected from rats and mice, and sequences similar to an unnamed bartonella sp. detected in rodents from china were detected in rats as well as a genotype of bartonella closely related to barton ...201122153359
epidemiology of bartonella infection in rodents and shrews in taiwan.during the period of august 2002 and november 2004, an epidemiological investigation for bartonella infection was conducted in small mammals in taiwan. using whole blood culture on chocolate agar plates, bartonella species were successfully isolated from 41.3% of the 310 animals tested. the isolation rate of bartonella species varied among different animal species, including 52.7% of the 169 rattus norvegicus, 28.6% of the 126 sucus murinus, 10% of the 10 rattus rattus and 66.7% of the three rat ...201019538457
variability of bartonella genotypes among small mammals in spain.in order to study which bartonella genotypes are circulating among small mammals in spain, we analyzed the spleens of 395 animals from three different areas-247 animals from the basque country (northern spain), 121 animals from catalonia (northeastern spain), and 27 animals from madrid (central spain)-by a triplex pcr combined with a reverse line blot previously described by our group. the prevalence of bartonella was 26.8% (106/395), and in 4.8% (19/395) of the animals more than one bartonella ...201020935117
bartonella infection in shelter cats and dogs and their ectoparasites.abstract mainly through vector transmission, domestic cats and dogs are infected by several bartonella spp. and represent a large reservoir for human infections. this study investigated the relationship of prevalences of bartonella infection in shelter dogs and cats and various ectoparasite species infesting them (fleas, ticks, and lice). moreover, relationships between bartonella infection and animal gender and age and presence of ectoparasites were analyzed. blood samples were collected from 1 ...201021142966
deficiencies in suppressor t cell activity seen in patients with active systemic lupus erythematosus are due to the dilution of normally functioning suppressor t cells by nonsuppressor t cells.concanavalin a (con a)-activated t lymphocytes from patients with active, but not inactive, systemic lupus erythematosus (sle) failed to express normal suppressor activity, regardless of the phenotype of cd4+ or cd8+. con a-activated cd4+ or cd8+ t lymphocytes from the sle patients and from normal controls were further separated into two populations, using the autologous erythrocyte rosette technique. one population very rich in cells capable of forming rosettes with autologous erythrocytes from ...20102946769
the jama journal club. 20102911174
isolation and genetic characterization of a bartonella strain closely related to bartonella tribocorum and bartonella elizabethae in israeli commensal rats.ten bartonella isolates were cultured from blood drawn from black rats (rattus rattus) captured in the tel aviv area. genetic characterization included amplification and sequencing of five gene fragments including the ribc, rpob, 16s, groel, and glta and the 16s-23s intergenic spacer region. sequence comparisons showed that all 10 isolates were identical in all genes studied comprising a total of 3,873 bp analyzed. the sequences of each of the partial genes analyzed indicated a high sequence sim ...200919556567
prevalence and genetic heterogeneity of bartonella strains cultured from rodents from 17 provinces in thailand.to study the distribution and diversity of bartonella in rodents from thailand, 330 rodents belonging to 13 species were tested. the majority (80.6%) of rodents examined belonged to the genus rattus. bartonellae were cultured from 41.5% of the rodents with a wide range of prevalence by host species and regions. sequencing of glta revealed diverse bartonella strains. bartonellae from rattus spp. belonged to 23 variants and clustered with bartonella coopersplainensis, bartonella elizabethae, barto ...200919861616
diarrhoeal diseases: perceptions and practices in nepal.a study undertaken in nepal collected information on believed causes of diarrhoea and traditional treatments. natural causes for diarrhoea were more frequently reported than supernatural causes, the most important being teething (75% of respondents reporting it to be a cause) followed by food considered to be 'cold' in the hindu ayurvedic classification (57.5%), stale food (52.5%), hot food (41%) and dirty water (38%). the terminology reported for dehydration however, indicates strong links with ...20092928835
[present state of conservative breast therapy in canada]. 20082746948
bartonella dna in the blood and lymph nodes of golden retrievers with lymphoma and in healthy controls.although lymphoma is the most common neoplastic process reported in dogs, its precise etiology is unknown. golden retrievers are more likely to develop lymphoma, suggesting a breed predisposition; however, other factors, including environment, immunity, and infection, are likely contributors to oncogenesis.200818289294
molecular evidence for bartonella spp. in cat and dog fleas from germany and france.nine hundred and fifty-two fleas were collected from 148 cats and 133 dogs at 18 widely distributed geographic locations in germany and france and examined for the presence of six different bartonella spp. (bartonella bacilliformis, bartonella clarridgeiae, bartonella elizabethae, bartonella henselae, bartonella quintana, bartonella vinsonii subsp. berkhoffii) by pcr. thirty-five specimens (3.7%) tested positive for either b. henselae (14 positive fleas) or b. clarridgeiae (21 positive fleas). d ...200818489542
isolation of bartonella species from rodents in taiwan including a strain closely related to 'bartonella rochalimae' from rattus norvegicus.an increasing number of bartonella species originally isolated from small mammals have been identified as emerging human pathogens. during an investigation of bartonella infection in rodent populations carried out in taiwan in 2006, a total of 58 rodents were tested. it was determined that 10.3 % (6/58) of the animals were bartonella bacteraemic. after pcr/rflp analysis, four isolates were identified as bartonella elizabethae and one isolate as bartonella tribocorum. however, there was one speci ...200819018019
the emergence of a health insurance system in a developing country: the case of south korea.in an attempt to understand the social forces and the economic and political conditions under which new social policies emerge in developing countries, this study outlines factors affecting the introduction of the health insurance system in south korea. the emergence of the south korean health insurance system was influenced by changing labor needs of the industrial sector, increasing social expectations, external and international pressures, increasing medical costs, and class conflict. these p ...20082600387
phase ii study of combining vinblastine and cyclosporin-a to circumvent multidrug resistance in renal cell cancer. 20071868026
overdose of cyclobenzaprine, the tricyclic muscle relaxant.a case of cyclobenzaprine (flexeril) overdose in a 31-year-old woman is presented. the treatment rendered was analogous to treatment protocols implemented for tricyclic overdose. a review of the pharmacology of cyclobenzaprine, as well as the management of patients who overdose on this drug, is presented.20072870671
a survey of zoonotic pathogens carried by norway rats in baltimore, maryland, usa.norway rats (rattus norvegicus) carry several zoonotic pathogens and because rats and humans live in close proximity in urban environments, there exists potential for transmission. to identify zoonotic agents carried by rats in baltimore, maryland, usa, we live-trapped 201 rats during 2005-2006 and screened them for a panel of viruses, bacteria, and parasites. antibodies against seoul virus (57.7%), hepatitis e virus (hev, 73.5%), leptospira interrogans (65.3%), bartonella elizabethae (34.1%), a ...200717224086
bartonella strains in small mammals from dhaka, bangladesh, related to bartonella in america and europe.ecological and bacteriologic observations of small mammals captured in dhaka, bangladesh, indicated that bartonella infections occurred in high prevalence among lesser bandicoot rats (bandicota bengalensis), black rats (rattus rattus), and house shrews (suncus murinus). sequence analysis of the citrate synthase gene of bartonella isolates showed that small mammals in bangladesh harbored a diverse assemblage of strains. some cultures were genetically related to bartonella elizabethae, a species i ...200717827381
selective vestibular neurectomy through the posterior fossa in ménière's disease.the authors report on a series of 18 patients operated through the posterior fossa approach for selective vestibular neurectomy. the indication for surgery consisted of intractable vertigo in cases of ménière's disease. results were excellent with a 94% cure of vertigo and 100% improvement. postoperative hearing results were good with 78% of patients maintaining their discrimination score and 94% their pure tone average threshold. the results and the advantages of this approach are discussed and ...20073225882
molecular detection of rickettsia felis, rickettsia typhi and two genotypes closely related to bartonella elizabethae.a total of 56 fleas were collected from mice, rats, and one hedgehog in national parks of mainland portugal and the madeira island. all fleas were tested for the presence of bacteria of the genera rickettsia and bartonella using pcr assays. in fleas from mainland portugal, we detected rickettsia felis in one archaeopsylla erinacei maura flea and in one ctenophtalmus sp. in five leptopsylla segnis fleas taken from rats in the madeira island, we identified rickettsia typhi. in addition, in four fl ...200617038702
the role of macrophages in the generation of t-helper cells. ii. the genetic control of the macrophage-t-cell interaction for helper cell induction with soluble antigens.helper cell induction to nonparticle antigens in vitro requires the cooperation of t cells and macrophages, but does not occur if the macrophages are allogenic. the reasons for this were investigated. malfunction of allogenic macrophages was excluded by cultures with their syngenic t cells; suppressor cell induction was excluded by admixture experiments. thus, t cells and macrophages only cooperated if they were genetically similar. the genetic locus (loci) involved was mapped. using congenic li ...20051079849
electrocardiographic changes under moderate hypoxia. 2005546723
chemotherapy in advanced gastric cancer: a controlled, prospective, randomised multi-centre study.seventy-six patients with advanced gastric adenocarcinoma were studied in a prospecitive, randmoised, controlled trial using vincristine, methotrexate, cyclophosphamide, and 5-fluorouracil in an initiation course and mitomycin-c with 5-fluorouracil as maintenance therapy. thirty-seven patients were inoperable and 39 had the primary tumour resected with histological evidence of residual disease. survival in the inoperable group was short and showed no significant difference between treated and co ...2004387542
jaundice. clinical pearls and perils revisited.i recount some clinical "pearls and perils" to help reassess the contributions of abdominal ultrasound, cholangiography, needle biopsy of the liver, and laparoscopy. abdominal ultrasound demonstrates stones in the gallbladder in approximately 98% of cases, but in only 15% in the common bile duct, whereas computerized tomography scan reveals them in greater than or equal to 50%. on cholangiography a blood clot (in hemobilia) may closely resemble a common duct stone, as may spasm or tumor of the d ...20032958535
detection and characterization of feline bartonella henselae in the czech republic.the aims of the study were to characterize isolates of bartonella henselae and to determine the prevalence of bacteremic domestic cats in urban and suburban parts of prague, czech republic. five (18%) gram-negative fastidious bacterial single-cat isolates were recovered from 27 hemocultures incubated without previous freezing. four of these isolates originated from flea infested stray cats (n=6) and one from a shelter cat without any ectoparasites (n=21). none of the 34 previously frozen specime ...200312695049
bartonella spp. antibodies in forensic samples from swedish heroin addicts.a high frequency of bartonella elizabethae seropositivity (39%) was recorded among intravenous heroin addicts in stockholm, sweden, who died from a lethal injection. some of the b. elizabethae-seropositive individuals also had antibodies to b. henselae houston-1, b. grahamii, and b. quintana, but none had antibodies to b. henselae marseille or b. vinsonii subsp. vinsonii. hepatitis was a frequent finding but no case had peliosis hepatitis. there was no case of endocarditis, but in three persons ...200312860665
[aging of the crystillin]. 2002130884
phylogenetic classification of bartonella species by comparing groel sequences.bartonella is a bacterial genus classified in the alpha-proteobacteria on the basis of 165 rdna sequence comparison. the highly conserved heat-shock chaperonin protein, groel, has proved to be a valuable resolving tool to classify ten bartonella species. the groel gene was amplified and sequenced from ten bartonella isolates: bartonella alsatica, bartonella vinsonii subsp. arupensis, bartonella taylorii, bartonella tribocorum, bartonella birtlesii, bartonella henselae marseille (urlly8), b. hens ...200211837299
genetic and ecologic characteristics of bartonella communities in rodents in southern china.ecologic and bacteriologic observations of small mammals captured in yunnan province in the people's republic of china indicated that bartonella infections occurred at a high prevalence among some rodent species. sequence analyses of the citrate synthase genes of these bartonella demonstrated that rodents in this region harbored a diverse assemblage of strains. the bartonella isolates obtained from apodemus, eothenomys, and rattus typically clustered separately by genus of rodent host. cultures ...200212201602
prevalence study of antibody to ratborne pathogens and other agents among patients using a free clinic in downtown los angeles.norway rats (rattus norvegicus) are hosts for various microbes. homeless people who have contact with rats may be at risk of infection by them. the los angeles county department of health services initiated a seroepidemiologic study among patients who used a free clinic in downtown los angeles; 200 serum specimens obtained for other routine assays were tested for antibodies to ratborne pathogens and other agents. the seroprevalence of antibody to hepatitis e virus in this population was 13.6%; t ...200212447746
the measurement of oestrone, equilin and dehydroepiandrosterone in the peripheral plasma of pregnant pony mares by radioimmunoassay. 2002154595
the clinical response of 328 private patients to acupuncture therapy.it is the attempt of this study to determine the efficacy of response to acupuncture at 24 hours, one week, and three week intervals at the end of a series of treatments in 328 patients. treated for a variety of disorders, approximately 60% had satisfactory responses of up to 3 weeks duration. the 328 patients were classified into 13 categories of problem disorders: headaches, cervical pain, lumbar pain without radiation, lumbar pain with radiation, isolated sciatica, parathoracic pain, knee pai ...2002123703
[thrombocytopenias. radioisotope studies. platelet survival studies]. 2002120271
comments on references to the american board of psychiatry and neurology in an article. 20023369584
bartonella henselae and bartonella elizabethae as potential canine pathogens.bartonella henselae or bartonella elizabethae dna from edta-anticoagulated blood samples obtained from four dogs was amplified and sequenced. the results showed that b. elizabethae should be added to the list of bartonella species (i.e., b. vinsonii subsp. berkhoffii, b. henselae, and b. clarridgeiae) that are currently recognized as infectious agents in dogs. furthermore, these results may have potential zoonotic implications, particularly if dogs can serve as a previously unrecognized reservoi ...200212454170
control of thyroglobulin synthesis and secretion (second of two parts). 200188013
effects of pure chlorobiphenyls (2,4',5-trichlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl) on the reproductive capacity in female mice.the effects of two pure chlorobiphenyls (2,4',5-trichlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl) on the reproductive capacity in female mice have been studied. the results obtained show that females given 0.5 mg 2,5',5-trichlorobiphenyl (tcb)/day or 0.5 mg 2,2',4,4',5,5'-hexachlorobiphenyl (hcb)/day for six consecutive days, starting on the first day of pregnancy, have significantly lower frequencies of implanted ova than the control females, whereas the frequency of implanted ova does n ...200197920
trauma care: don't forget the patient. nursing grand rounds. 200188032
urban zoonoses caused by bartonella, coxiella, ehrlichia, and rickettsia species.the last half of the 20th century witnessed an increase in the occurrence and recognition of urban zoonoses caused by members of the genera bartonella, coxiella, ehrlichia, and rickettsia, all traditionally considered to be members of the family rickettsiaceae. in recent years, new human pathogens (bartonella elizabethae, bartonella henselae, and rickettsia felis) have been recognized in urban environments. other newly recognized pathogens (ehrlichia chaffeensis and ehrlichia phagocytophila in t ...200112653141
[immunohistochemical study of the differentiation of the cephalic lobe of the adenohypophysis in chick embryos].it was shown by means of indirect immunofluorescence that acth appeared in the cephalic lobe of the chick embryo pituitary beginning from the 8th day of the development. a new tissue-specific antigen (a3) is revealed, which is localized in the cephalic lobe of adenohypophysis and becomes manifest at the 7th day of embryogenesis. quantitative analysis of acth and a3 localization in the cells of 11-day chick embryo adenohypophyses allows a conclusion that a3 is localized in corticotropic cells.200188969
effect of radiotherapy on the neutrophil and the lymphocyte enzymatic equipment and serum immunoglobulins in patients with cancer of the larynx.in 30 patients with cancer of the larynx, aged 40 to 70 years, treated by radiotherapy 6 to 9 years ago the decreased activity of neutrophil beta-glucuronidase and n-acetyl-beta-glucosaminidase accompanied by a decrease of absolute count of enzyme-positive cells was noted. numbers of acid phosphatase-positive neutrophils were also decreased. moderate increase of the neutrophil alkaline phosphatase activity and of numbers of enzyme-positive cells was another observed feature. the main finding in ...200188387
adult respiratory-distress syndrome in salicylate intoxication. 200187755
molecular phylogeny of the genus bartonella: what is the current knowledge?species of the genus bartonella are involved in an increasing variety of human diseases. in addition to the 14 currently recognized species, several bartonella strains have been recovered from a wide range of wild and domestic mammals in europe and america. such a high diversity of geographic distributions, animal reservoirs, arthropod vectors and pathogenic properties makes clarification of our knowledge about the phylogeny of bartonella species necessary. phylogenetic data have been inferred m ...200111410341
in vitro susceptibilities of bartonella and rickettsia spp. to fluoroquinolone antibiotics as determined by immunofluorescent antibody analysis of infected vero cell monolayers.the in vitro susceptibilities of bartonella and rickettsia spp. to different concentrations of ciprofloxacin, levofloxacin, ofloxacin and sparfloxacin in vero cell cultures, were determined by enumeration of immunofluorescent-stained bacilli. after incubation in a co(2)-enriched atmosphere, inocula were replaced and tested with media containing 12 different concentrations of each antibiotic in replicate for each species and the monolayers were re-incubated. growth status was determined by evalua ...200111673033
evidence of rodent-associated bartonella and rickettsia infections among intravenous drug users from central and east harlem, new york city.we tested serum samples collected in 1997 and 1998 from a cohort of 204 injection drug users (idus) recruited from central and east harlem, new york city, new york, for antibodies reactive with seven rickettsial or bartonella spp. antigens. rodent-associated bartonella elizabethae and rickettsia akari were the primary etiologic agents of interest. the testing panel also included bartonella henselae, bartonella quintana, rickettsia prowazekii, rickettsia rickettsii, and rickettsia typhi. the high ...200111791987
in vitro susceptibilities of rickettsia and bartonella spp. to 14-hydroxy-clarithromycin as determined by immunofluorescent antibody analysis of infected vero cell monolayers.the in vitro susceptibilities of rickettsia akari, rickettsia conorii, rickettsia prowazekii, rickettsia rickettsii, bartonella elizabethae, bartonella henselae and bartonella quintana to different concentrations of clarithromycin, 14-hydroxy-clarithromycin (the primary metabolite of clarithromycin) and tetracycline in vero cell cultures, were determined by enumeration of immunofluorescently-stained bacilli. the extent of antibiotic-induced inhibition of foci was recorded for each dilution of an ...200010702548
a bacteriophage-like particle from bartonella bacilliformis.bartonella bacilliformis and bartonella henselae, the respective agents of oroya fever and cat-scratch disease in humans, are known to produce bacteriophage-like particles (blps) that package 14 kbp segments of the host chromosome. data from this study suggest that other bartonella species including bartonella quintana, bartonella doshiae and bartonella grahamii also contain similar blps, as evidenced by the presence of a 14 kbp extrachromosomal dna element in their genomes, whereas bartonella e ...200010746763
cardiac tamponade and peripheral eosinophilia in a patient receiving cromolyn sodium. 200095924
journal of autism and childhood schizophrenia. change of journal scope and title. 200086533
comparison of metal complexes between depyruvamide bleomycin and bleomycin: an important effect of axial donor on metal coordination and oxygen activation. 200088941
general-practice training, exeter style. 200087562
x-associated immunocompetence. 199984980
axonal transport of lipid in goldfish optic axons.after injection of labeled glycerol, choline, or serine into the eye of goldfish, labeled lipids were axonally transported along the optic nerve to the optic tectum. although the different precursors were presumably incorporated into somewhat different lipid populations, all three were approximately equally effective in labeling the lipids transported to the tectum, but the amount of transported material remaining in the nerve was different, being highest with choline and lowest with serine. the ...199985271
[irradiation combined with bleomycin. 5-year results with 27 o.r.l. epitheliomas (proceedings)]. 199985709
chemotherapy of head and neck cancer: combination treatment with cyclophosphamide, adriamycin, methotrexate, and bleomycin.a combination of cyclophosphamide, adriamycin, methotrexate, and bleomycin (camb) was explored in patients with advanced, nonresectable epidermoid carcinoma from primary sites in the head and neck, recurrent or persistent after radiation or surgery. objective regression (greater than 50%) of measurable tumor was present in 35% of the patients. the median duration of response was 2.5 months. median survival of responders was slightly less than the nonresponders, but the difference was not signifi ...199985249
Displaying items 1 - 100 of 146