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serum alkaline phosphatase activity in acrodermatitis enteropathica: an index of the serum zinc level.a significant positive correlation between serum zinc and serum alkaline phosphatase levels was demonstrated in four patients suffering from acrodermatitis enterophathica for which they received oral zinc sulphate therapy. in one of the male patients a significant inverse relation between serum zinc and serum copper was found.199984482
x-associated immunocompetence. 199984980
chemotherapy of head and neck cancer: combination treatment with cyclophosphamide, adriamycin, methotrexate, and bleomycin.a combination of cyclophosphamide, adriamycin, methotrexate, and bleomycin (camb) was explored in patients with advanced, nonresectable epidermoid carcinoma from primary sites in the head and neck, recurrent or persistent after radiation or surgery. objective regression (greater than 50%) of measurable tumor was present in 35% of the patients. the median duration of response was 2.5 months. median survival of responders was slightly less than the nonresponders, but the difference was not signifi ...199985249
axonal transport of lipid in goldfish optic axons.after injection of labeled glycerol, choline, or serine into the eye of goldfish, labeled lipids were axonally transported along the optic nerve to the optic tectum. although the different precursors were presumably incorporated into somewhat different lipid populations, all three were approximately equally effective in labeling the lipids transported to the tectum, but the amount of transported material remaining in the nerve was different, being highest with choline and lowest with serine. the ...199985271
[role of anti-brain antibodies in the development of mineralocorticoid deficiency]. 197985292
an experimental study on the effect of plasma expanders on blood coagulability.the effect of various plasma expanders on blood coagulation was studied using the thromboelastography (teg). solutions of 5, 10, 20, and 50% concentration of each expander (6% low molecular weight hydroxyethyl-starch (6% hespander), 3% dextran-40, 6% high molecular weight hydroxyethyl-starch (6 hes), and 6% dextran-70) or solvent (lactated ringer solution and normal saline) in blood were prepared and their coagulability was examined by teg. in the low molecular weight plasma expanders (6% hespan ...199985502
[relationship of the structure of specific somatic antigen polysaccharides in shigella dysenteriae bacteriae to the immunochemical properties]. 197985516
[irradiation combined with bleomycin. 5-year results with 27 o.r.l. epitheliomas (proceedings)]. 199985709
preganglionic neurons in the sacral spinal cord of the rat: an hrp study. 197986176
journal of autism and childhood schizophrenia. change of journal scope and title. 200086533
potentiating effect of nitrate and other anions on contraction in vascular smooth muscle. 197887173
general-practice training, exeter style. 200087562
adult respiratory-distress syndrome in salicylate intoxication. 200187755
control of thyroglobulin synthesis and secretion (second of two parts). 200188013
trauma care: don't forget the patient. nursing grand rounds. 200188032
immunologic studies of native and modified human factor viii/von willebrand factor.factor viii/von willebrand factor (fviii/vwf) is a glycoprotein with a molecular weight greater than one-million daltons. two activities are associated with this large molecule: fviii procoagulant activity and vwf activity. incubation of fviii/vwf with proteolytic enzymes causes rapid inactivation of the fviii procoagulant activity but has little effect on the vwf activity or antigenicity. in an attempt to gain insight into the structural features required for these two activities, antisera were ...197988237
hippocampal evoked potentials and eeg changes during classical conditioning in the rat.hippocampal evoked potentials (eps) and eeg responses were studied in rats, using a classical conditioning paradigm (water, us), with a spatially discontiguous cs-us arrangement in order to separate the cs and goal-related responses. in early training, when the orienting score was high, the tone cs, instead of eliciting a definite ep, usually reset hippocampal theta activity in phase, i.e. theta rhythm became time-locked to cs. with further training, orienting activity (ori) decreased to the pre ...197988362
effect of radiotherapy on the neutrophil and the lymphocyte enzymatic equipment and serum immunoglobulins in patients with cancer of the larynx.in 30 patients with cancer of the larynx, aged 40 to 70 years, treated by radiotherapy 6 to 9 years ago the decreased activity of neutrophil beta-glucuronidase and n-acetyl-beta-glucosaminidase accompanied by a decrease of absolute count of enzyme-positive cells was noted. numbers of acid phosphatase-positive neutrophils were also decreased. moderate increase of the neutrophil alkaline phosphatase activity and of numbers of enzyme-positive cells was another observed feature. the main finding in ...200188387
chunking in recall of symbolic drawings. 199988658
comparison of metal complexes between depyruvamide bleomycin and bleomycin: an important effect of axial donor on metal coordination and oxygen activation. 200088941
[immunohistochemical study of the differentiation of the cephalic lobe of the adenohypophysis in chick embryos].it was shown by means of indirect immunofluorescence that acth appeared in the cephalic lobe of the chick embryo pituitary beginning from the 8th day of the development. a new tissue-specific antigen (a3) is revealed, which is localized in the cephalic lobe of adenohypophysis and becomes manifest at the 7th day of embryogenesis. quantitative analysis of acth and a3 localization in the cells of 11-day chick embryo adenohypophyses allows a conclusion that a3 is localized in corticotropic cells.200188969
intensive care and the very low birthweight infant. 199989424
[indications for relief and palliative operations].torkildsen and spitz-holter drainages and/or osteoclastic trepanation were performed on 29 patients suffering from a severe increase in intracranial pressure and/or a severely worsened general condition as a relieving intervention in order to permit a tumor operation later. the relieving measure enabled a tumor operation in 28 patients. the same procedure was used as a palliative step for another group of 73 patients suffering from inoperable tumorous processes. evaluation in these cases showed ...199995657
minoxidil in resistant hypertension.minoxidil in combination with propranolol and diuretics controlled the blood-pressure in a group of hypertensive patients who were resistant to treatment with large doses of standard drugs. the main problem was fluid retention but subjective side-effects were fewer than in a comparable group on other drugs.199995728
deficiency of the ninth component of complement in man.the studies of serum from a case with c9 (the ninth component of complement) deficiency are described. a 29-year-old woman in good health was found to have low serum complement levels (ch50). c9 of her serum was undetectable by the hemolytic assay and by the immunochemical analysis but all other components were normal. it was demonstrated that low ch50 of her serum was due to the hemolysis of the sensitized sheep erythrocytes (ea) by the complement components from c1 to c8.197995812
[the lice of the gerbils of tajikistan].2606 gerbils of four species from tajikistan were examined. on them there were found over 14 thousand sucking lice of 10 species, four of which are typical to gerbils. hoplopleura merionidis ferris is a mongolian-turkestan species, which in central asia parasitizes meriones meridianus pallas and m. unguiculatus milne-edw. and in middle asia--m. meridianus and m. erythrourus gray, seldom m. tamariscinus pallas. polyplax chinensis ferris, a parasite of m. meridianus, is a mongolian-turkestan speci ...197995816
[the adrenergic innervation of the thoracic lymphatic duct in dogs in postnatal ontogeny].using histochemical fluorescence technique, studies have been made on the adrenergic innervation of the wall of the thoracal lymphatic duct in postnatal development of puppies. adrenergic fibers were found in the adventitial layer of the duct. during postnatal development of the animals, adrenergic innervation of this duct becomes more perfect, reaching the level of adult animals to the age of 2-3 months.197995857
cardiac tamponade and peripheral eosinophilia in a patient receiving cromolyn sodium. 200095924
naturally occurring diatomaceous pneumoconiosis in sub-human primates. 197896157
[clinical use of the trh-tsh stimulation test with special reference to pediatric thyroid-gland diseases]. 199996623
effects of pure chlorobiphenyls (2,4',5-trichlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl) on the reproductive capacity in female mice.the effects of two pure chlorobiphenyls (2,4',5-trichlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl) on the reproductive capacity in female mice have been studied. the results obtained show that females given 0.5 mg 2,5',5-trichlorobiphenyl (tcb)/day or 0.5 mg 2,2',4,4',5,5'-hexachlorobiphenyl (hcb)/day for six consecutive days, starting on the first day of pregnancy, have significantly lower frequencies of implanted ova than the control females, whereas the frequency of implanted ova does n ...200197920
administration of thyrotropin releasing hormone (trh) to rats releases dopamine in n. accumbens but not n. caudatus. 1979105304
[thrombocytopenias. radioisotope studies. platelet survival studies]. 2002120271
the clinical response of 328 private patients to acupuncture therapy.it is the attempt of this study to determine the efficacy of response to acupuncture at 24 hours, one week, and three week intervals at the end of a series of treatments in 328 patients. treated for a variety of disorders, approximately 60% had satisfactory responses of up to 3 weeks duration. the 328 patients were classified into 13 categories of problem disorders: headaches, cervical pain, lumbar pain without radiation, lumbar pain with radiation, isolated sciatica, parathoracic pain, knee pai ...2002123703
[aging of the crystillin]. 2002130884
the measurement of oestrone, equilin and dehydroepiandrosterone in the peripheral plasma of pregnant pony mares by radioimmunoassay. 2002154595
steroid production by quartered and capsular rat adrenal gland in response to haemorrhage.60 min after rapid bleeding (1.5--2.0 per cent of b. w.) both aldosterone and corticosterone production rate by quartered rat adrenals were found to be elevated. however, no difference was observed in the rate of aldosterone and corticosterone production by capsular adrenals of sham operated and hypovolaemic rats. corticosterone production rate by decapsulated adrenals was much more higher after haemorrhage than in the control group. the same alterations could be observed incubating adrenal tiss ...1975179800
effects of althesin and its steroidal components on a variety of excised smooth muscle preparations. 1979262472
chemotherapy in advanced gastric cancer: a controlled, prospective, randomised multi-centre study.seventy-six patients with advanced gastric adenocarcinoma were studied in a prospecitive, randmoised, controlled trial using vincristine, methotrexate, cyclophosphamide, and 5-fluorouracil in an initiation course and mitomycin-c with 5-fluorouracil as maintenance therapy. thirty-seven patients were inoperable and 39 had the primary tumour resected with histological evidence of residual disease. survival in the inoperable group was short and showed no significant difference between treated and co ...2004387542
electrocardiographic changes under moderate hypoxia. 2005546723
[effect of aflatoxin b 1 on respiration and oxidative phosphorylation in the rabbit. ii. research on cardiac and renal mitochondria].the effect of various concentrations of aflatoxin b1 (ab1) is studied "in vitro" on heart (hm) and kidney mitochondria of rabbit (km). ab1 inhibits (4 x 10(-4)m) the respiratory rate up to a maximum 50-35% in hm and 28-35% in km by glutamate and succinate as substrates respectively, but it does not uncouple oxidative phosphorylation nor does it inhibit site iii (ascorbate + tmpd). the inhibited site appears to be between cytochromes b and c (c1). ab1 seems to be easily transported across heart m ...1979548060
the role of macrophages in the generation of t-helper cells. ii. the genetic control of the macrophage-t-cell interaction for helper cell induction with soluble antigens.helper cell induction to nonparticle antigens in vitro requires the cooperation of t cells and macrophages, but does not occur if the macrophages are allogenic. the reasons for this were investigated. malfunction of allogenic macrophages was excluded by cultures with their syngenic t cells; suppressor cell induction was excluded by admixture experiments. thus, t cells and macrophages only cooperated if they were genetically similar. the genetic locus (loci) involved was mapped. using congenic li ...20051079849
phase ii study of combining vinblastine and cyclosporin-a to circumvent multidrug resistance in renal cell cancer. 20071868026
structure of the human centromere at metaphase.until recently the centromere was thought to be a relatively homogeneous region of densely packed heterochromatin with a single differentiated domain--the kinetochore--at its surface, representing the point of attachment of the mitotic spindle. we now know that the centromere of higher eukaryotes is composed of several domains that have been identified using antibody probes. somewhere within the domains are located both the factor(s) that control the disjunction of sister chromatids and the mole ...19902193435
air sampling for legionella. 19902232037
modification of allergen-induced airway obstruction and airway hyperresponsiveness in an allergic rabbit model by the selective platelet-activating factor antagonist, bn 52021.allergen challenge of eight ragweed-immunized rabbits elicited a prolonged airway obstruction that was evident during the 6-hour study period. airway responsiveness to histamine was enhanced 24 hours after allergen exposure (geometric mean of the 50% reduction in effective dose [ed50] of dynamic compliance [cdyn] before challenge, 3.46 mg/ml, decreased to 0.52 mg/ml after challenge, p less than 0.01; pulmonary resistance ed50 geometric mean before challenge, 3.50 mg/ml, decreased to 0.65 mg/ml a ...19892600327
the emergence of a health insurance system in a developing country: the case of south korea.in an attempt to understand the social forces and the economic and political conditions under which new social policies emerge in developing countries, this study outlines factors affecting the introduction of the health insurance system in south korea. the emergence of the south korean health insurance system was influenced by changing labor needs of the industrial sector, increasing social expectations, external and international pressures, increasing medical costs, and class conflict. these p ...20082600387
[tumor metastasis and growth factors].massive investigations are being carried out on growth factors. growth factors are an important determinant for the formation of successive tumor metastasis at target organs. we review the findings, including our data, of growth factors in relation to tumor metastasis.19892679395
[present state of conservative breast therapy in canada]. 20082746948
[experimental study on the changes of bile acids and their fractions after liver ischemia].serum bile acids and their fractions in the systemic and portal vein were measured after liver ischemia of 0, 30, 60, and 90 minutes with extracorporeal venous bypass in 20 dogs. the following results were obtained: 1) total concentration of bile acids in the serum rapidly increased during the ischemic phase because of extinction of enterohepatic circulation due to flow of portal blood into the systemic circulation. 2) portal blood flow decreased after recirculation of the liver, and this decrea ...19892811841
overdose of cyclobenzaprine, the tricyclic muscle relaxant.a case of cyclobenzaprine (flexeril) overdose in a 31-year-old woman is presented. the treatment rendered was analogous to treatment protocols implemented for tricyclic overdose. a review of the pharmacology of cyclobenzaprine, as well as the management of patients who overdose on this drug, is presented.20072870671
the jama journal club. 20102911174
diarrhoeal diseases: perceptions and practices in nepal.a study undertaken in nepal collected information on believed causes of diarrhoea and traditional treatments. natural causes for diarrhoea were more frequently reported than supernatural causes, the most important being teething (75% of respondents reporting it to be a cause) followed by food considered to be 'cold' in the hindu ayurvedic classification (57.5%), stale food (52.5%), hot food (41%) and dirty water (38%). the terminology reported for dehydration however, indicates strong links with ...20092928835
deficiencies in suppressor t cell activity seen in patients with active systemic lupus erythematosus are due to the dilution of normally functioning suppressor t cells by nonsuppressor t cells.concanavalin a (con a)-activated t lymphocytes from patients with active, but not inactive, systemic lupus erythematosus (sle) failed to express normal suppressor activity, regardless of the phenotype of cd4+ or cd8+. con a-activated cd4+ or cd8+ t lymphocytes from the sle patients and from normal controls were further separated into two populations, using the autologous erythrocyte rosette technique. one population very rich in cells capable of forming rosettes with autologous erythrocytes from ...20102946769
jaundice. clinical pearls and perils revisited.i recount some clinical "pearls and perils" to help reassess the contributions of abdominal ultrasound, cholangiography, needle biopsy of the liver, and laparoscopy. abdominal ultrasound demonstrates stones in the gallbladder in approximately 98% of cases, but in only 15% in the common bile duct, whereas computerized tomography scan reveals them in greater than or equal to 50%. on cholangiography a blood clot (in hemobilia) may closely resemble a common duct stone, as may spasm or tumor of the d ...20032958535
[distribution of antibodies against the human t-cell leukemia virus in healthy venezuelan adults]. 19853008469
estrogenic control of spermidine/spermine n1-acetyltransferase activity in rat uterus. 19883076330
selective vestibular neurectomy through the posterior fossa in ménière's disease.the authors report on a series of 18 patients operated through the posterior fossa approach for selective vestibular neurectomy. the indication for surgery consisted of intractable vertigo in cases of ménière's disease. results were excellent with a 94% cure of vertigo and 100% improvement. postoperative hearing results were good with 78% of patients maintaining their discrimination score and 94% their pure tone average threshold. the results and the advantages of this approach are discussed and ...20073225882
reflections from a decade of carotid reconstructive surgery.carotid artery reconstructive surgery for atherosclerotic lesions of the extracranial cerebral circulation has become the most common operation in peripheral vascular surgery. a better understanding of the indications for operative intervention, enhanced monitoring during surgery, and more precise management of intraoperative anesthesia have all helped decrease the risks associated with internal carotid endarterectomy. to evaluate the safety and efficacy of extracranial carotid reconstructive su ...20123358162
comments on references to the american board of psychiatry and neurology in an article. 20023369584
rural hospitals rely more on outpatient revenue. 20123391547
basal metabolism of obese adolescents: inconsistent diet and exercise effects.effects of 20 wk of diet-plus-behavior (db) therapy or exercise-plus-diet-plus-behavior (edb) therapy on changes in basal energy expenditure (bee) were studied in 36 obese male and female adolescents. bee was assessed by open-circuit spirometry and body composition by hydrostatic weighing. dietary restriction was based on the dietary-exchange program. behavioral treatment included record-keeping, stimulus-control, and reinforcement techniques. edb therapy included 50 min/d, 3 d/wk of aerobics. a ...20123414571
mallet fractures.contrary to our observations, reports in the literature maintain that only a third of mallet finger deformities are caused by intra-articular fractures of the posterior margin of the distal phalanx. as functional impairment sometimes remains after treatment, there is still much discussion as to the relative merits of conservative and surgical management of this lesion. this article presents 21 cases of mallet finger deformities with fracture of the distal phalanx, of which 17 received surgical t ...20123426323
high mutagenic activity of 3-azido-1,2-propanediol (azidoglycerol, ag) in strain d7 of saccharomyces cerevisiae.3-azido-1,2-propanediol (azidoglycerol, ag) showed a high mutagenicity in strain d7 of saccharomyces cerevisiae. at 5 mm it increased the spontaneous frequency of isoleucine revertants 3500 times and the frequency of gene convertants 3000 times during 24 h of growth, reducing the growth rate to 30%. in non-growth conditions, treatment with 150 mm of ag for 3 h reduced cell survival to 60% and enhanced the frequency of isoleucine revertants 490 times and tryptophan-independent convertants 50 time ...19873553915
effects of noise on pure-tone thresholds in blackbirds (agelaius phoeniceus and molothrus ater) and pigeons (columba livia).blackbirds and pigeons were trained to detect tones in quiet and in broadband noise by using positive-reinforcement techniques. in experiment 1, thresholds in noise were obtained in blackbirds as a function of both tone frequency and noise intensity for a pulsed noise masker (noise gated on and off with tone). for blackbirds, critical ratios (the ratio of the power of the just-detectable tone in noise to the power of the noise masker) obtained in pulsed noise showed no consistent relation to ton ...19873568604
plasma exchange for failure of early resuscitation in thermal injuries. 20133648044
radiometric-high-performance liquid chromatographic assay for nicotine and twelve of its metabolites.a sensitive, reproducible radiometric-high-performance liquid chromatographic assay has been developed to measure concentrations of nicotine and twelve of its metabolites in biological fluids. following administration of nicotine ([2-14c]pyrrolidine) to rats, the assay was used in a pharmacokinetic investigation.19873667778
hypercalcemia and acute renal insufficiency in a 24-year-old white male with lung disease. 20133754694
vulvovaginal reconstruction following radical resections. 20123757340
findings with cis-z-clopenthixol in the treatment of acute mania and schizophrenia.the authors report the results of an open clinical trial with cis(z)-clopenthixol (cisordinol), the isolated cis-isomer of the clopenthixol racemate (sordinol). the drug was applied to 18 patients with severe forms of manic or schizophrenic disease, diagnosed according to icd 9. the compound was applied intravenously or orally, daily doses ranging from 10-160 mg. for the duration of the study (6 weeks) the patients were repeatedly rated with the cgi, bprs or imps (abbreviated version), and sever ...20133797470
plasmodium falciparum malaria: band 3 as a possible receptor during invasion of human erythrocytes.human erythrocyte band 3, a major membrane-spanning protein, was purified and incorporated into liposomes. these liposomes, at nanomolar concentrations of protein, inhibited invasion of human erythrocytes in vitro by the malaria parasite plasmodium falciparum. liposomes containing human band 3 were ten times more effective in inhibiting invasion than those with pig band 3 and six times more effective than liposomes containing human erythrocyte glycophorin. liposomes alone or liposomes containing ...19853880920
assessment of a bubble tonometer as a quality control system for blood gas analyzers (po2 and pco2).a blood gas tonometer device, comprising an accurate gas mixer (corning 192) associated with a dual channel bubble tonometer (corning 184) was tested for reliability, accuracy and ease of use as a quality control system for po2 and pco2 blood gas analyzers. from our results it is apparent that this system can be used instead of older and more bulky tonometry devices, gas mixing systems or cylinders of fixed composition.20133889784
comparative efficacy of calcium antagonist drugs in the prophylaxis of migraine. 20133908401
injury to the glenoid fossa.an illustrated case of fracture through the confines of the glenoid fossa by the mandibular condyle is presented. the mechanism of injury and postinjury sequelae of this rarely reported but frequently suspected occurrence are discussed and a treatment rationale proposed. the key to the diagnosis of this entity is an awareness of vector forces directed to the region of the glenoid fossa with or without evidence of subcondylar fracture.20143945692
comparison of two statistical techniques for the surveillance of birth defects through a monte carlo simulation. 20143961319
design and data quality of a mixed longitudinal study to elucidate the role of dietary calcium and phosphorus on bone mineralization in pre-, peri-, and postmenopausal women.the study design and data quality control of an ongoing study (10 yr duration) in a few hundred women are presented. good variables with respect to their longitudinal usefulness are: body weight, body height, and span-width. reasonable variables are the bone parameters of the radius (bmc, bw, and bmc/bw). poor variables are: dietary calcium and phosphorus intake, dietary calcium-to-phosphorus ratio, urinary calcium-to-creatinine ratio, urinary sodium-to-creatinine ratio, hematocrit, serum alkali ...20143962907
the temporal evolution of hypoglycemic brain damage. i. light- and electron-microscopic findings in the rat cerebral cortex.in the course of a study on the pathogenesis of neuronal necrosis in severe hypoglycemia, the morphological characteristics reflecting reversible and irreversible neuronal lesions were examined as a function of time following normalization of blood glucose. to that end, closely spaced time intervals were studied in the rat cerebral cortex before, during, and up to 1 year after standardized pure hypoglycemic insults of 30 and 60 min of cerebral isoelectricity. both the superficial and deep layers ...19854024866
histogenesis of malignant melanoma with an adjacent component of the superficial spreading type.there has been a world-wide exponential increase in the incidence of thin malignant melanoma. at the sydney melanoma unit, the proportion of patients diagnosed as having superficial spreading melanoma has more than doubled from 33% prior to 1960 to 78% during 1980-83. a study was made of the non-invasive component of malignant melanoma with an adjacent non-invasive component of the superficial spreading type in an attempt to elucidate the pathogenetic mechanisms involved in these changing trends ...20144047726
editorial: carotid endarterectomy and t.i.a. 20144128839
gonococcal conjunctivitis. 19744205793
[uterine metastasis from a colloid epithelioma of the appendix]. 20154350561
formation of lithogenic bile in man. 19734362764
characterization of phospholipase b of culex pipiens fatigans.phospholipase b has been found in the mosquito culex pipiens fatigans, and some of its properties have been studied. the enzyme had a high optimum temperature (45 degrees c) and broad alkaline ph optimum (8-9). it was inactive toward diacylphospholipids, and hydrolyzed lysolecithin at a higher rate than lysophosphatidyl ethanolamine. the enzyme was heat labile, but lysolecithin protected it against heat inactivation. phosphatidyl ethanolamine, phosphatidyl choline, deoxycholate, fe(+++), and hg( ...19694390654
changes in renal size following intra-arterial administration of water-soluble contrast medium. 20154430589
are tranquilizers used as "chemical strait-jackets"? do adequate safeguards exist? 20154481720
[use of l-asparaginase in therapy with special reference to acute lymphatic leukemia]. 20154502507
blood and plasma ascorbic acid in indian childhood cirrhosis. 20164784731
prolonged control of increased intracranial pressure with glycerin. 20125049685
[cat-scratch disease and disease caused by bartonella (rochalimaea)].the aetiology of cat scratch disease remains controversial since both afipia felis and bartonella (rochalimaea) henselae have been isolated from diseased lymph nodes. bartonella henselae, bartonella (rochalimaea) quintana and bartonella (rochalimaea) elizabethae cause endocarditis and bartonella bacilliformis cause septicemia (oroya's fever) in non-immunocompromized patients, and bartonella henselae and bartonella quintana cause fever, bacillary angiomatosis, and visceral peliosis in human immun ...19957534931
use of bartonella antigens for serologic diagnosis of cat-scratch disease at a national referral center.bartonella henselae (formerly the genus rochalimaea) has recently been isolated from patients with cat-scratch disease and their cats, and since september 1992 the centers for disease control and prevention has offered an indirect fluorescent antibody assay for bartonella-specific antibody.19957542443
rochalimaea elizabethae sp. nov. isolated from a patient with endocarditis.a rochalimaea-like organism (strain f9251) was isolated from a patient with endocarditis after blood drawn for culture before antimicrobial therapy was subcultured onto blood and chocolate agars and incubated for 2 weeks in 5% co2. the strain was phenotypically similar to known rochalimaea species. the cellular fatty acid composition of strain f9251 was close to but distinct from those of the three known rochalimaea species and was most similar to that of r. vinsonii. labeled dna from strain f92 ...19937681847
proposals to unify the genera bartonella and rochalimaea, with descriptions of bartonella quintana comb. nov., bartonella vinsonii comb. nov., bartonella henselae comb. nov., and bartonella elizabethae comb. nov., and to remove the family bartonellaceae from the order rickettsiales.dna hybridization data (hydroxyapatite method, 50 to 70 degrees c) indicate that rickettsia prowazekii, the type species of the type genus of the family rickettsiaceae, is substantially less closely related to rochalimaea species than was previously thought. the levels of relatedness of rickettsia prowazekii to rochalimaea species and to bartonella bacilliformis under optimal conditions for dna reassociation were 0 to 14%, with 25.5% or greater divergence in related sequences. when stringent rea ...19938240958
comparison of partial citrate synthase gene (glta) sequences for phylogenetic analysis of bartonella species.nucleotide base sequence data were obtained for a 940-bp fragment of the citrate synthase-encoding gene (glta) of representatives of the eight validly described bartonella species and seven uncharacterized bartonella strains obtained from small mammals. complete 16s rrna gene sequences were also determined for the uncharacterized strains, and these sequences revealed that each strain had a unique sequence which was very similar to the sequences of the previously recognized bartonella species. a ...19968863415
antibodies to bartonella species in inner-city intravenous drug users in baltimore, md.bartonella quintana has recently been associated with homeless alcoholic men. both b quintana and bartonella henselae have been shown to be opportunistic pathogens of people with acquired immunodeficiency syndrome. the reservoirs and modes of transmission of these infections are incompletely known.19968944742
leber's neuroretinitis in a patient with serologic evidence of bartonella elizabethae. 19989654422
bartonella tribocorum sp. nov., a new bartonella species isolated from the blood of wild rats.two bartonella strains from blood of two wild rats (rattus norvegicus) living in a rural environment were isolated. these strains were distinct from all previously known bartonella species based on phenotypic and genotypic characteristics. this new species is distinguished by its trypsin-like activity, the absence of the ability to hydrolyse proline and tributyrin, its 16s rrna and citrate synthase gene sequences and by whole-dna hybridization data. this new species, for which the name bartonell ...19989828434
rats of the genus rattus are reservoir hosts for pathogenic bartonella species: an old world origin for a new world disease?bartonella species were isolated from the blood of 63 of 325 rattus norvegicus and 11 of 92 rattus rattus from 13 sites in the united states and portugal. infection in both rattus species ranged from 0% (e.g., 0/87) to approximately 60% (e.g., 35/62). a 337-bp fragment of the citrate synthase (glta) gene amplified by polymerase chain reaction was sequenced from all 74 isolates. isolates from r. norvegicus were most similar to bartonella elizabethae, isolated previously from a patient with endoca ...199910353885
in vitro susceptibilities of rickettsia and bartonella spp. to 14-hydroxy-clarithromycin as determined by immunofluorescent antibody analysis of infected vero cell monolayers.the in vitro susceptibilities of rickettsia akari, rickettsia conorii, rickettsia prowazekii, rickettsia rickettsii, bartonella elizabethae, bartonella henselae and bartonella quintana to different concentrations of clarithromycin, 14-hydroxy-clarithromycin (the primary metabolite of clarithromycin) and tetracycline in vero cell cultures, were determined by enumeration of immunofluorescently-stained bacilli. the extent of antibiotic-induced inhibition of foci was recorded for each dilution of an ...200010702548
a bacteriophage-like particle from bartonella bacilliformis.bartonella bacilliformis and bartonella henselae, the respective agents of oroya fever and cat-scratch disease in humans, are known to produce bacteriophage-like particles (blps) that package 14 kbp segments of the host chromosome. data from this study suggest that other bartonella species including bartonella quintana, bartonella doshiae and bartonella grahamii also contain similar blps, as evidenced by the presence of a 14 kbp extrachromosomal dna element in their genomes, whereas bartonella e ...200010746763
molecular phylogeny of the genus bartonella: what is the current knowledge?species of the genus bartonella are involved in an increasing variety of human diseases. in addition to the 14 currently recognized species, several bartonella strains have been recovered from a wide range of wild and domestic mammals in europe and america. such a high diversity of geographic distributions, animal reservoirs, arthropod vectors and pathogenic properties makes clarification of our knowledge about the phylogeny of bartonella species necessary. phylogenetic data have been inferred m ...200111410341
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