Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| bidirectional transfer between kindling induced by excitatory amino acids and electrical stimulation. | chemical (c) kindling by means of repeated spaced injections into the amygdala (am) of a subconvulsive dose of l-glutamate and l-aspartate combined in a molar ratio of 1:3. (glu/asp) produced progressive seizure development culminating in generalized convulsion strikingly similar to electrically kindled stage 5 seizure in rats. these c-kindled am sites responded readily to electrical stimulation with very rapid development of kindled seizure. when a separate group of rats electrically kindled at ... | 1987 | 2892570 |
| involvement of postsynaptic adrenergic mechanism(s) in the atp-contractions of the rat anococcygeus muscle and the effect of extracellular ca2+. | clonidine, ici-106270 (6-aryl 2,367 tetrahydro 5-h-pyrrolo(1,2-a)-imidazole derivative), b-ht-920 (6-allyl-2-amino-5,6,7,8-tetrahydro-4h-thiozolo = [4,5-d]azepine-dihydrochloride, and guanfacine, agonists at alpha 2-adrenoceptors, produced concentration-dependent contractions of the rat anococcygeus muscle. the order of potency of these agonists in producing the response was clonidine greater than ici-106270 greater than guanfacine greater than b-ht 920. yohimbine (10(-6) m) competitively antago ... | 1988 | 2896487 |
| the glutamate receptor subtype mediating parallel fibre-purkinje cell transmission in rabbit cerebellar cortex. | responses of purkinje cells to parallel fibre stimulation and to ionophoretically applied glutamate agonists, l-glutamate, l-aspartate, quisqualate, kainate and n-methyl-d-aspartate (nmda), were extracellularly recorded in a superficial folium of the dorsal paraflocculus of high-decerebrate rabbits. nmda caused an inhibition of simple spike discharge from purkinje cells. 2-amino-5-phosphonovalerate (apv), a selective nmda receptor antagonist, effectively antagonized this inhibition. however, apv ... | 1988 | 2897650 |
| [prenatal diagnosis of duchenne muscular dystrophy using dna rflp analysis]. | 2010 | 2907413 | |
| diverticular disease of the appendix. | a retrospective study of diverticular disease of the appendix was made in 3,343 consecutive instances of appendectomies. a 2 per cent incidence of diverticular disease was found. these instances were classified into four morphologic types: 1, acute diverticulitis; 2, acute appendicitis with acute diverticulitis; 3, acute appendicitis with diverticulum, and 4, appendix with diverticulum. types 1, 2 and 3 were divided into subgroups with or without perforation. the elements of clinical behavior in ... | 2009 | 2909128 |
| a new technique for use of an anomalous subclavian artery for a systemic-pulmonary arterial shunt. | anomalous subclavian arteries were used as interposition grafts for systemic-pulmonary arterial shunts in three infants and children with good early and long-term results. this is the first report of the use of an anomalous subclavian artery as an interposition graft for a systemic-pulmonary arterial shunt. the advantages and effectiveness of the technique are discussed. | 2010 | 2911186 |
| synthesis and copper-dependent antimycoplasmal activity of 1-amino-3-(2-pyridyl)isoquinoline derivatives. 2. amidines. | in our search for new compounds with antimycoplasmal activity, a series of aromatic amidines derived from 1-amino-3-(2-pyridyl)isoquinoline (1) was synthesized. in the presence of 40 microm copper the most active compounds show growth inhibition of mycoplasma gallisepticum in the nanomolar range. these compounds are 3 times as active as tylosin, an antimycoplasmal therapeutic agent that is used in veterinary practice. in the presence of copper, amidines derived from 1 are 2-3 times more active t ... | 1989 | 2913309 |
| improved sexual function in hemodialysis patients on recombinant erythropoietin: a possible role for prolactin. | as it was reported that correction of anemia in long-term hemodialysis patients by recombinant human erythropoietin (r-huepo) is associated with improved sexual function, we conducted the present study to further delineate the mechanism(s) by which this is brought about. serum prolactin, testosterone, and parathyroid hormone (pth) levels were followed during 4 months of r-huepo therapy. within 4 months of treatment with r-huepo, hematocrit values rose from 23.7 +/- 1.2 to 35.7 +/- 0.2% and hemog ... | 1989 | 2914405 |
| potassium secretion by the cortical collecting tubule: effect of c1 gradients and ouabain. | in various epithelia k and cl transport are molecularly coupled and kcl cotransport is dependent on the na-k pump. the present study examines 1) the effect of a bath-to-lumen cl gradient on k secretion during active na transport and 2) the effect of basolateral ouabain on k secretion and na absorption in the presence and the absence of a bath-to-lumen cl gradient. under symmetrical conditions there was significant k secretion (jk = -24.0 +/- 3.9 pmol.mm-1.min-1) and cl secretion (jcl = -15.7 +/- ... | 1989 | 2916662 |
| energy metabolism of monocytic ehrlichia. | we investigated if the monocytic ehrlichia are totally dependent on their host cells for energy, or, as rickettsia, are capable of some atp synthesis in vitro. the miyayama strain of ehrlichia sennetsu and the maryland and illinois strains of ehrlichia risticii were cultivated in a mouse macrophage cell line, separated from host cell constituents by procedures that included renografin or percoll gradient centrifugation, and tested after cryopreservation. cells incubated without a metabolizing su ... | 1989 | 2922404 |
| diarrhoeal diseases: perceptions and practices in nepal. | a study undertaken in nepal collected information on believed causes of diarrhoea and traditional treatments. natural causes for diarrhoea were more frequently reported than supernatural causes, the most important being teething (75% of respondents reporting it to be a cause) followed by food considered to be 'cold' in the hindu ayurvedic classification (57.5%), stale food (52.5%), hot food (41%) and dirty water (38%). the terminology reported for dehydration however, indicates strong links with ... | 2009 | 2928835 |
| homonymous hemianopsia due to posterior ischemia as a model for quantification of neurologic deficit. | 2010 | 2929034 | |
| human t helper cells specific for antigens of typhus group rickettsiae enhance natural killer cell activity in vitro. | the peripheral blood mononuclear cells (pbmc) from 5 individuals immune to typhus group rickettsiae and from 13 nonimmune individuals were stimulated in vitro for 7 days with typhus group rickettsial antigen (tgra). at the end of day 7, lysis of the natural killer (nk)-susceptible target k562 by these pbmc was determined. as controls, pbmc from both groups of donors were cultured in vitro for 7 days without antigen or were freshly isolated, and lysis of the k562 target was determined. there was ... | 1986 | 2945787 |
| jaundice. clinical pearls and perils revisited. | i recount some clinical "pearls and perils" to help reassess the contributions of abdominal ultrasound, cholangiography, needle biopsy of the liver, and laparoscopy. abdominal ultrasound demonstrates stones in the gallbladder in approximately 98% of cases, but in only 15% in the common bile duct, whereas computerized tomography scan reveals them in greater than or equal to 50%. on cholangiography a blood clot (in hemobilia) may closely resemble a common duct stone, as may spasm or tumor of the d ... | 2003 | 2958535 |
| cutaneous reactions to vitamin k. | in four patients the development of erythematous plaques after vitamin k injections was apparently due to delayed hypersensitivity reactions. the 36 cases described in the literature indicate that most patients with the reaction received vitamin k injections for liver disease and that a late sclerodermatous reaction develops rarely. | 2003 | 2972759 |
| cellular receptors for type beta transforming growth factor. ligand binding and affinity labeling in human and rodent cell lines. | type beta transforming growth factor (beta tgf) purified from human platelets to homogeneity as judged by nh2-terminal amino acid sequence analysis has been labeled with 125i to characterize its interaction with cellular receptors. binding of 125i-beta tgf to target cells is temperature- and time-dependent, specific, saturable, and reversible. about 1.6-1.9 x 10(4) binding sites/cell with high affinity for beta tgf (kd = 5.6-7.8 x 10(-11) m and 9.1-14 x 10(-11) m, respectively) are found in nrk- ... | 1985 | 2982829 |
| constitutive and conditional suppression of exogenous and endogenous genes by anti-sense rna. | plasmid dna directing transcription of the noncoding (anti-sense) dna strand can specifically inhibit the expression of several test genes as well as normal, endogenous genes. the anti-sense plasmid constructions can be introduced into eukaryotic cells by transfection or microinjection and function in both transient and stable transformation assays. anti-sense transcripts complementary to as little as 52 bases of 5' untranslated target gene mrna specifically suppress gene activity as well as, or ... | 1985 | 2990048 |
| prevalence and distribution of spotted fever and typhus infections in sierra leone and ivory coast. | a serosurvey for evidence of rickettsial infections was conducted in the rural populations of several tropical rain forest areas in sierra leone and ivory coast. seropositivity rates were surprisingly high in both countries, with more than 7% of the individuals in some districts having antibodies to spotted fever-group rickettsiae. no significant difference was found in the overall prevalence of diagnostic antibody titers to spotted fever-group rickettsiae in sierra leone (5.3%) and ivory coast ... | 1986 | 3025125 |
| sulbactam plus ampicillin: interim review of efficacy and safety for therapeutic and prophylactic use. | the efficacy and safety of sulbactam/ampicillin has been evaluated in 39 studies of therapeutic use and six studies of prophylaxis. studies of therapy were conducted in 899 patients: 751 seriously ill, many of whom had multiple concurrent diseases, and 148 with gonorrhea. overall clinical and bacteriologic success was achieved in 92% of assessable cases; 88% of 768 pathogens in these patients were eradicated. of these pathogens, 43% were resistant to ampicillin; eradication rates of 91% and 85% ... | 2011 | 3026019 |
| effects of "partial axotomy" upon synaptic function. | a lesion limited to the dorsal columns, at the level of l3-l4, was carried out in chronic cats. this operation produced a "partial axotomy" type of lesion on the ascending branches of ia hind limb afferents. two to six months after this operation, intracellular studies on l7-s1 motoneurons were carried out. similar studies were done in normal animals. the peak amplitude and the rate of rise (dv/dt) of heteronymous epsp's were studied during control conditions (sampling at 1 hz) and during the po ... | 1986 | 3026830 |
| [herpes genitalis, in prostitutes. detection of asymptomatic viral excretors and their epidemiological role]. | 1986 | 3027823 | |
| [contribution of phlebography in the surgical treatment of chronic venous insufficiency of the lower extremities]. | in which circumstances does a surgeon request phlebograms and which ones? what is the contribution of phlebography regarding therapeutic indications and surgical technique. | 2011 | 3043471 |
| [x-ray computed tomography in venous pathology]. | after presenting the tomodensitometric semiology of venous thromboses in various territories, the authors define its indications. it is essentially in deep territories, head, chest and abdomen that the ct-scan is used to study and diagnose unrecognized thromboses as well as determine the venous repercussion of various neighboring ailments. the respective place of the ct-scan, ultrasonography and various phlebographies is analyzed. | 2011 | 3043474 |
| [accuracy of fit of castings in relation to impression, model and technical parameters]. | 2011 | 3044749 | |
| multiple subdural abscesses following colonic perforation--a rare complication of a ventriculoperitoneal shunt. | a case of colonic perforation by a ventriculoperitoneal shunt, its subsequent migration and protrusion from the anal orifice is reported. the shunt reservoir and ventricular catheter were removed percutaneously, and the disconnected peritoneal catheter was pulled out through the anus. blood culture grew klebsiella pneumoniae and streptococcus fecalis. ct scan showed multiple subdural abscesses with evidence of ventriculitis. removal of the shunt (as described), evacuation of subdural pus and sys ... | 1988 | 3050846 |
| characterization of mannoproteins from a virulent candida albicans strain and its derived, avirulent strain. | antigenic differences between a wild-type virulent strain of candida albicans 4918 (wt) and its spontaneous avirulent mutant (m-10) were found with crossed-immunoelectrophoresis and western blotting. mannoprotein fractions from yeast and mycelial forms were obtained by affinity chromatography on concanavalin a and analyzed with use of patient sera or sera from rabbits infected with live wt cells and boosted with whole extracts or rabbits immunized with purified wt cell wall preparations. a spike ... | 1988 | 3055210 |
| cyclophosphamide-induced liver necrosis: a possible interaction with azathioprine. | cyclophosphamide is a valuable drug for the treatment of vasculitis and hepatic toxicity resulting from its use has been reported rarely. we describe four patients in whom cyclophosphamide was associated with liver injury when its administration had been preceded by azathioprine. microscopy of hepatic biopsy material in three of these cases showed liver cell necrosis. in two of the patients, cyclophosphamide had been given previously without earlier azathioprine and hepatic damage had not been n ... | 2011 | 3060893 |
| within-subjects, parametric manipulations to investigate aging. | parametric manipulation of experimental variables is important for both practical and theoretical reasons. practically, age-related impairments in memory may be detected only at certain levels of difficulty. if the task is too simple, age-related cognitive impairments may not be sufficient to alter performance. if the task is too difficult, age-related cognitive impairments may not add significantly to the poor performance of younger controls. thus, some intermediate level of difficulty is neces ... | 1988 | 3062458 |
| estrogenic control of spermidine/spermine n1-acetyltransferase activity in rat uterus. | 1988 | 3076330 | |
| [treatment of 75 patients with malaria caused by plasmodium falciparum, in porto velho (rondonia), with mefloquine]. | 1988 | 3078220 | |
| altered cell cycle phase distributions in cultured human carcinoma cells partially depleted of polyamines by treatment with difluoromethylornithine. | we have studied the effects of partial polyamine depletion, induced by treatment with alpha-difluoromethylornithine (dfmo) on cell cycle phase distributions in five cultured human carcinoma cell lines. we used flow cytometry of cells stained with chromomycin-a3 and computer analysis to measure phase distributions of treated and control cultures. all five lines respond to 1-5 mm dfmo treatment with a total absence of measurable putrescine, a loss of greater than 90% of spermidine, and a 30-40% de ... | 1986 | 3079590 |
| mechanisms of immunity to rickettsial infection: characterization of a cytotoxic effector cell. | rickettsiae, as other intracellular bacteria, are relatively sequestered from the effects of antibody and local antibody-independent responses. considering the obligate intracellular nature of rickettsia, the exact mechanisms by which lymphocytes and macrophages encounter rickettsial antigens and eliminate the infection depends upon the appropriate presentation of antigen to the immune system. we demonstrate here that cells taken from the spleens of rickettsia typhi- or r. tsutsugamushi-infected ... | 1986 | 3080523 |
| characterization of human cytotoxic lymphocytes directed against cells infected with typhus group rickettsiae: evidence for lymphokine activation of effectors. | an in vitro culture and assay system was used to determine whether cytotoxic lymphocytes are generated in humans after rickettsial infection. peripheral blood mononuclear cells (pbmc) were obtained from six individuals with serologic evidence of prior infection with typhus group rickettsiae and from six nonimmune individuals. after pbmc from immune individuals were stimulated in vitro for 7 days with rickettsial antigen, they were capable of lysing typhus group rickettsia-infected, autologous ph ... | 1986 | 3081648 |
| positive correlation between the level of protein-carboxyl methylase in spermatozoa and sperm motility. | levels of protein-carboxyl methylase (pcm) activity were measured in spermatozoa from infertile patients with less than 50% sperm motility and compared with those of normal fertile controls. when spermatozoa were washed by a standard centrifugation procedure, the level of pcm activity in a subgroup of patients with sperm motility ranging from 0% and 20% (24.0 +/- 5.2 pmol/mg protein, mean +/- standard error of the mean) was significantly different from that of controls (35.9 +/- 2.3 pmol/mg). ho ... | 2011 | 3086132 |
| lymphokine-activated-killer-mediated lysis of cells infected with typhus group rickettsiae can be inhibited by okt3 monoclonal antibody. | we examined the ability of monoclonal antibodies directed against lymphocyte surface antigens to block the lysis of typhus group rickettsia-infected cells by lymphokine-activated killer effectors. lysis was significantly inhibited by okt3 monoclonal antibody but not by okt4 or okt8 monoclonal antibody. | 1986 | 3087881 |
| an endemic focus of murine typhus in europe. | 1986 | 3090154 | |
| aflatoxins in the livers of children with kwashiorkor in ghana. | autopsy liver specimens from 22 kwashiorkor children in ghana were analysed for the presence of aflatoxins using both high performance liquid chromatography and thin layer chromatography. aflatoxin b1 was found in the livers of 20 subjects and aflatoxicol in the livers of the remaining two subjects. these results confirm previous findings of aflatoxin b1 and aflatoxicol in the livers of children with kwashiorkor and provide further evidence of associations between these toxic compounds and kwash ... | 2011 | 3092419 |
| the effects of alpha adrenergic blockade on arachidonic acid metabolism and shock sequelae in endotoxemia. | previous studies have suggested that increased alpha adrenergic activity stimulated prostaglandin synthesis and may be involved in the modulation of eicosanoid metabolism. these observations prompted investigation of the effect of the alpha adrenergic receptor antagonist phenoxybenzamine and the cyclo-oxygenase inhibitor indomethacin on endotoxin-induced shock severity, and on plasma immunoreactive itxb2 and i6-keto-pgf1 alpha, the stable metabolites of txa2 and pgi2, respectively. pretreatment ... | 1986 | 3096591 |
| serological cross-reactions between rickettsia typhi, proteus vulgaris ox19, and legionella bozemanii in a series of febrile patients. | the sera of 19 patients with a febrile disease of undetermined etiology were positive in the indirect immunofluorescence assay (ifa) to legionella bozemanii serogroup 1 (lb) and rickettsia typhi (rt). to both antigens, high titers of igg-class and igm-class antibodies were demonstrated. several of the patients also had positive ifa and weil-felix reactions to proteus vulgaris ox19 (px 19). a sharp reduction of the serotiters to all three antigens was achieved by absorption of the sera with any o ... | 1986 | 3098699 |
| a serological survey of scrub, tick, and endemic typhus in sabah, east malaysia. | a seroepidemiological survey of 837 people and 383 febrile patients was performed in rural areas of sabah. we determined that the rickettsial diseases scrub typhus and endemic typhus were uncommon causes of febrile illness, as was tick typhus, except in forest dwelling peoples. the rate of occurrence of sfgr specific antibody was 16.5% among 412 forest dwellers, indicating that tick typhus may be a frequent cause of illness in this population. | 1986 | 3107139 |
| serologic evidence of acute murine typhus infection in a patient with culture-negative endocarditis. | a patient with culture-negative infective endocarditis is presented in whom detailed serological studies were indicative of acute infection with murine typhus. the patient had aortic and mitral regurgitation with congestive heart failure and typical peripheral manifestations of subacute endocarditis, but no documented fever. aortic and mitral valve replacement surgery and a 6-week course of doxycycline therapy produced a clinical cure in this patient, as well as a diagnostic fall in markedly ele ... | 1987 | 3109241 |
| suppression of rickettsia typhi transmission in fleas maintained on murine typhus-immune rats. | the presence of host antibodies against rickettsia typhi in the hemolymph of xenopsylla cheopis fed on immune rats was studied using an indirect immunofluorescent antibody (ifa) test and enzyme-linked immunosorbent assay (elisa). the time course experiment revealed that antibody to r. typhi appears in the flea hemolymph after 18 hr exposure to host and persists for 24 hr. ifa tests utilizing specific antisera to rat igg (fc) and rat igg (fab) fragments, indicate that some unaltered rat igg to r. ... | 1987 | 3120611 |
| lysis of cells infected with typhus group rickettsiae by a human cytotoxic t cell clone. | cytolytic human t cell clones generated in response to the intracellular bacterium rickettsia typhi were characterized. growing clones were tested for their ability to proliferate specifically in response to antigens derived from typhus group rickettsiae or to lyse targets infected with r. typhi or rickettsia prowazekii. two clones were able to lyse targets infected with typhus group rickettsiae. one of these clones was more fully characterized because of its rapid growth characteristics. this c ... | 1987 | 3121731 |
| transmission of murine typhus rickettsiae by leptopsylla segnis (siphonaptera: leptopsyllidae). | 1987 | 3121858 | |
| [gastric carcinoid associated with duodenal diverticulum]. | 2011 | 3121905 | |
| murine typhus among khmers living at an evacuation site on the thai-kampuchean border. | an outbreak of febrile disease involving 170 khmer adults at an evacuation site in thailand occurred during the dry season of 1986, only 8 months after the camp was constructed. the illnesses were characterized by persistent fever, retro-orbital headache, myalgias, and clinical response to tetracycline within 2-3 days. the symptoms, effectiveness of tetracycline, and presence of a large rat population raised the suspicion of murine typhus. fourteen (74%) of 19 patients had elevated or rising ant ... | 1988 | 3124646 |
| regulation of ige synthesis in atopic disease. | 2011 | 3125207 | |
| intravenous indomethacin for postoperative pain. a double-blind study of ankle surgery. | intravenous indomethacin infusion (75 mg/10 h) for relief of pain after ankle surgery was compared with placebo in a double-blind study. ninety-seven patients were operated on for a malleolar fracture or ruptured ligament of the ankle under single-dose spinal anesthesia. in the indomethacin group, 14 out of 49 patients were free from pain, 4/47 in the control group. severe pain was experienced by 24/49 in the indomethacin group and by 41/47 in the control group. supplementary intramuscular oxyco ... | 2011 | 3128054 |
| update: acquired immunodeficiency syndrome (aids)--worldwide. | as of march 21, 1988, 136 countries or territories throughout the world had reported a total of 84,256 cases of aids to the global programme on aids (gpa) (formerly the special programme on aids) of the world health organization (who). 37 countries or territories had reported no aids cases. reports are based on either the centers for disease control (cdc)/who surveillance definition, the who clinical definition, or a physician's diagnosis. from 1979 through march 21, 1988, the number of aids cas ... | 2011 | 3129644 |
| [experimental chemo- and chemoendocrine therapy of human breast carcinomas serially transplanted into nude mice]. | four human breast carcinoma strains serially transplanted into nude mice were used for the experimental chemotherapy and combination chemoendocrine therapy. whereas three of these strains (mcf-7, br-10, tm-61) possessed cytosol estrogen receptor (erc) and were dependent on estradiol for the tumor growth, the other strain (mx-1) without erc was hormone independent. for the chemotherapy, mitomycin c (mmc), adriamycin (adm), cyclophosphamide (cpm) and 5-fluorouracil (5-fu) were administered 3 times ... | 1988 | 3129645 |
| recognition of typhus group rickettsia-infected targets by human lymphokine-activated killer cells. | lymphokine-activated killer cells caused significant lysis of target cells infected with typhus group rickettsiae (tgr) but not cells infected with rickettsia tsutsugamushi. monoclonal and polyclonal antibodies against tgr or tgr-infected cells failed to bind specifically to infected targets, as determined by flow cytometry or by immunoprecipitation of radiolabeled cell surface proteins. major unaltered antigenic determinants of tgr therefore cannot be detected on the surface of infected targets ... | 1988 | 3137174 |
| tripelennamine enhances buprenorphine-, but not pentazocine-induced hyperactivity in mice. | the opioid agonist-antagonist pentazocine (1-30 mg/kg) and the partial agonist buprenorphine (0.05-0.25 mg/kg) were tested, alone or in combination with the histamine h1-receptor antagonist tripelennamine (1, 2.5, 5 or 10 mg/kg), on locomotor activity in mice of the cd-1 strain. when given alone, pentazocine produced slight and non-dose-related activity increments, while buprenorphine induced strong and dose-related locomotor stimulation. tripelennamine slightly increased activity by itself and ... | 2011 | 3137594 |
| ovarian carcinoma: abdominopelvic irradiation following reexploration. | twenty patients with ovarian cancer, who following reexploration were left with residual disease nodules of less than 2 cm diameter, received abdominopelvic irradiation. of these patients 18 had previous chemotherapy. fifteen patients completed treatment, 13 of whom had prior chemotherapy. six of the 18 patients with invasive tumors were alive and disease free 18-53 months postradiotherapy, while only 4 patients had died at the time of follow-up. no patient with residual nodules greater than 1 c ... | 2011 | 3141249 |
| newborn rats in the murine typhus enzootic infection cycle: studies on transplacental infection and passively acquired maternal antirickettsial antibodies. | this study focused attention on the newborn rat as a possible significant participant in the highly successful enzootic cycle of murine typhus. we examined the influence of maternal rickettsia typhi (r. mooseri) infection in rats on the offspring with respect to the possible vertical transmission of r. typhi and the passive transfer of maternal antirickettsial antibodies. transmission of r. typhi by rickettsemic pregnant rats did not occur either transplacentally during gestation to their fetuse ... | 1988 | 3142287 |
| role of natural killer cells in the early clearance of rickettsia typhi in mice. | 1988 | 3144156 | |
| a prolonged decline in the incidence of necrotizing enterocolitis after the introduction of a cautious feeding regimen. | 2011 | 3144829 | |
| report of the second public health service aids prevention and control conference. women and aids. | 2011 | 3147491 | |
| studies on the effect of long-term use of low dose aspirin in kawasaki disease. | 2011 | 3148261 | |
| creatinine excretion rates for evaluation of kidney function in children. | a protein load protocol for evaluation of kidney function was tested in normal children and pediatric renal patients. an overnight, timed urine collection was used for calculation of the baseline creatinine clearance and creatinine excretion rate. one hour following ingestion of a standardized protein meal (baked chicken), a 2-3 h urine collection was begun. the post-protein meal changes in creatinine clearance showed considerable variation in both the normal children and those with renal disord ... | 1988 | 3153054 |
| present criteria for the diagnosis of in vivo of olivopontocerebellar atrophy. | we present 6 cases of olivopontocerebellar atrophy (opca) of dèjérine-thomas type. the diagnosis was based on an appropriate clinical picture, anomalous brainstem auditory evoked potentials (baep) and computerized tomography (ct) and/or magnetic nuclear resonance (mnr) imaging which demonstrated atrophy of the cerebellum and the pons. we believe that these methods will provide greater uniformity in the diagnosis of such an heterogeneous entity as opca. | 2011 | 3163874 |
| antibacterial action of powdered semiconductor on a serotype g streptococcus mutans (short communication). | 1988 | 3165714 | |
| a new approach to the quality control of steroid receptor assays. | lyophilized cytosols prepared from calf uterus and human breast tumor tissue are commonly used to assess the reliability of routine steroid receptor assays. however, preanalytical error (sample preparation, storage, homogenization) cannot be detected in this way. participating laboratories were asked to mail us all their receptor results obtained over a four-month interval, and to include some information about the patients involved (age, menopausal status, nodal status). after verifying the hom ... | 1988 | 3168219 |
| the use of a pharmacological indicator to investigate compliance in patients with a poor response to antirheumatic therapy. | twenty-six patients with rheumatoid arthritis which was poorly controlled despite high dose d-penicillamine were studied. compliance was assessed by standard methods (return tablet count and interview). in addition low-dose phenobarbitone was included in the penicillamine formulation as a pharmacological indicator of compliance. using these techniques incomplete compliance was apparent in 11 patients (42%). all such patients were identified by the pharmacological marker. only one admitted poor c ... | 2009 | 3179627 |
| the use of a pharmacological indicator to investigate compliance in patients with a poor response to antirheumatic therapy. | twenty-six patients with rheumatoid arthritis which was poorly controlled despite high dose d-penicillamine were studied. compliance was assessed by standard methods (return tablet count and interview). in addition low-dose phenobarbitone was included in the penicillamine formulation as a pharmacological indicator of compliance. using these techniques incomplete compliance was apparent in 11 patients (42%). all such patients were identified by the pharmacological marker. only one admitted poor c ... | 2009 | 3179627 |
| training of general practitioners in interpreting chest radiographs. | easily accessible chest and skeleton roentgen examinations are needed in primary health care. in finland the health centres perform about a third of all roentgen examinations. many of the films are interpreted by health centre doctors at least in the primary phase. about 40% of them are chest radiographs. in 2640 chest radiographs interpreted by general practitioners the final roentgen diagnosis was pathological in 54%. pathological conditions were totally overlooked in 13%. of normal cases 19% ... | 2011 | 3205199 |
| [value of determining myoglobin and creatine phosphokinase levels in the evaluation of the cardiovascular status in children with acute pneumonia]. | 2011 | 3205644 | |
| hypocholesterolaemic effects of dietary propionate: studies in whole animals and perfused rat liver. | in adult male rats fed a non-purified diet supplemented with 5% sodium propionate, plasma cholesterol concentrations were significantly depressed. although liver cholesterol was increased by feeding propionate, rates of hepatic cholesterol and fatty acid synthesis were unchanged. tissue concentrations and rates of synthesis of cholesterol were also unaffected by dietary propionate in stomach, small intestine and caecum. concentrations of propionate in hepatic portal venous plasma were raised by ... | 1988 | 3214141 |
| [asymptomatic myocardial ischemia: which tests? which treatment?]. | 2011 | 3219450 | |
| serum free thyroxine and free tri-iodothyronine in normal children. | serum free thyroxine (ft4) and free tri-iodothyronine (ft3) were measured in 138 normal school children, adolescents and their younger siblings, whose ages ranged from 3 months to 18 years. mean ft4 concentration (16.8 pmol/l) was similar to the adult mean concentration of 17 pmol/l and all the values were within the adult reference range. at all ages the ft3 range was considerably higher than the adult reference range and the overall mean ft3 concentration (8.3 pmol/l) was at the upper limit of ... | 2011 | 3232955 |
| [prognostication of the outcome of traumatic disease and the optimal therapy at the initial period]. | 2012 | 3247108 | |
| [somatic effects of radiation]. | 2012 | 3254662 | |
| a request for hormone replacement therapy. | 2012 | 3255965 | |
| inhibition of the proliferative response of human b lymphocytes to b cell growth factor by transforming growth factor-beta. | the effects of transforming growth factor-beta (tgf-beta) on the proliferative response of human b cells to the low molecular weight b cell growth factor (bcgf) have been investigated in this study. it was found that tgf-beta, at picomolar concentrations, strongly inhibited the bcgf-induced proliferation of anti-mu chain or staphylococcus aureus cowan i-activated human b cells and also of a bcgf-dependent cell line derived from a human lymphocytic nodular lymphoma. this inhibitory effect was det ... | 1988 | 3257917 |
| [epidemiology of dental caries and periodontal disease in guatemala]. | 2012 | 3269012 | |
| [medium-term results of radial keratotomies and discussion]. | 2012 | 3269275 | |
| circular intermediates with missing nucleotides in the conversion of supercoiled or nicked circular to linear duplex dna catalyzed by two species of bal 31 nuclease. | the extracellular nucleases from alteromonas espejiana bal 31 can catalyze the endonucleolytic and/or exonucleolytic hydrolysis of duplex dna in response to a variety of alterations, either covalent or noncovalent, in dna structure. the nuclease can exist as at least two kinetically and molecularly distinct protein species. the two species that have been studied, called the 'fast' (f) and 'slow' (s) nucleases, both readily convert negatively supercoiled dnas to linear duplex molecules and accomp ... | 1988 | 3275464 |
| the effects of some synthetic prostanoids on the contractility of the human lower uterine segment in vitro. | we have investigated the ability of three synthetic prostanoids to directly influence uterine contractility by studying the effects in vitro. strips of lower uterine segment smooth muscle were obtained from women undergoing elective cesarean section at term. the ability of these strips to develop tension in the presence of cumulative additions of prostanoids or oxytocin was assessed. spontaneous contractions were inhibited by zk 96.480, a stable synthetic analog of prostaglandin i2, with a 50th ... | 1988 | 3277428 |
| is withdrawal of steroids hazardous to cadaveric renal transplants under treatment with cyclosporine? | 2006 | 3291225 | |
| results of conversion immunosuppression in 193 cadaver and 42 living-related donor renal allografts. | 2006 | 3291232 | |
| [thyroid cancer: new knowledge and therapeutic strategy in an endemic area]. | the epidemiological data of thyroid carcinoma are difficult to evaluate. several variables influence the biologic behaviour and the great number of occult papillary carcinomas obscure the picture. among our 1116 patients we found as first symptoms solitary nodules in 41,4% being localized in differentiated carcinomas significantly more frequently in the right than is the left lobe. multinodular goiter was seen in 24,2%, cervical lymph nodes in 10,9% and distant metastases in 3,2%. in medullary c ... | 2006 | 3291428 |
| the current status of panoramic radiography. | the current status of dental panoramic tomography (rotational panoramic radiography) is reviewed. this technique is based on a combination of tomography and slit-beam radiography to provide an image of both jaws on a single film. there is a greater degree of image degradation when compared with conventional radiographic techniques due to tomographic blurring, magnification and distortion, secondary images and burn-out. meticulous patient position is essential to accommodate their jaws to the ima ... | 2012 | 3294598 |
| the moral limits to federal funding for kidney disease. | in the current era of cost-containment, congress may reconsider its support for the end-stage renal disease program. substantial reductions in funding for this program could be made by eliminating non-beneficial, marginally beneficial, and relatively inefficient modes of treatment. these measures, however, will only postpone the inevitable day when clearly beneficial treatment must be withheld. | 2006 | 3294741 |
| [tumor necrosis factor]. | 2012 | 3310111 | |
| cardiac and great vessel trauma: assessment, pathophysiology, and intervention. | 2005 | 3320442 | |
| utilization of monoclonal antibody l26 in the identification and confirmation of b-cell lymphomas. a sensitive and specific marker applicable to formalin-and b5-fixed, paraffin-embedded tissues. | immunophenotypic analysis of paraffin-embedded tissues of lymphoproliferative disorders has been facilitated by recent developments of monoclonal antibodies that react with epitopes that survive histologic processing. leukocyte common antigen (lca) antibody has made a significant contribution to the immunocytochemical separation of non-hodgkin's lymphomas from nonlymphoid neoplasms. however, a small percentage of lymphomas, particularly some large cell or immunoblastic b-cell tumors, will not la ... | 2010 | 3322020 |
| autotransplantation of teeth; a review of current thoughts. | 2004 | 3323099 | |
| monensin inhibits secretion of extracellular matrix and the spreading of mesoderm cells in the early chick embryo. | chick embryos in culture were treated with the secretion-inhibiting ionophore monensin at the gastrulation stage of development. after treatment for 5 h at a concentration of 10(-5) m the embryos showed a drastic reduction in the tissue space between the upper and lower epithelia, and reduced spreading of the mesoderm cells that occupied this space. the basement membrane, to which many mesoderm cells are normally attached, showed varying degrees of disruption, which permitted blebbing of the ove ... | 2004 | 3323209 |
| pathological hyperprolactinemia suppresses hot flashes in menopausal women. | hyperprolactinemia impairs pituitary-gonadal function in young women, but its effect in menopausal women is not known. the purpose of this report is to describe the effect of hyperprolactinemia on gonadotropin secretion and hot flashes in menopausal women before and after treatment with a dopamine agonist. we studied two such women with prolactinomas. both had plasma lh and fsh levels in the range found in premenopausal women and no hot flashes. treatment with bromocriptine was associated with n ... | 2012 | 3346363 |
| 'treatment ind' is an oxymoron. | 2012 | 3352116 | |
| geriatric education: training and practice perspectives. | 2010 | 3358111 | |
| testosterone-sensitive vasotocin-immunoreactive cells and fibers in the canary brain. | a sexual difference in vasotocin (vt) immunoreactivity was observed in the canary brain. the male canary displays denser vt innervation of the lateral septum and more vt-immunoreactive cells are visible in the dorsal diencephalon than in the female canary. this sex difference is the consequence of gonadal influences. castration of male canaries resulted in a substantial decrease of vt immunoreactivity in these septal and diencephalic cells and fibers. testosterone administration to castrated mal ... | 1988 | 3359249 |
| modification of the response to opioid and nonopioid drugs by chronic opioid antagonist treatment. | chronic exposure to opioid antagonists increases the analgesic actions of opioids such as morphine. in the present studies, morphine's analgesic potency was increased (supersensitivity) following an 8 day subcutaneous naltrexone implant in mice, but not following a 1 day implant. supersensitivity was maximal 24hr following the 8 day implant and declined linearly and had returned to control levels by 120hr. implantation of naltrexone pellets for 8 days was found to increase the relative analgesic ... | 2012 | 3362035 |
| hypophosphatemia-associated respiratory muscle weakness in a general inpatient population. | although hypophosphatemia has been implicated as a cause of respiratory failure, its impact on respiratory muscle function in patients hospitalized for other reasons remains to be determined. maximal inspiratory pressures (mip) and maximal expiratory pressures (mep) were measured at the bedside in 23 hospitalized patients with serum phosphate levels less than 2.5 mg/dl, and these measurements were repeated daily during phosphate repletion until serum phosphate levels reached the normal range. a ... | 2012 | 3364446 |
| foot impact force and intravascular hemolysis during distance running. | this study was designed to examine the relationship between foot impact force and the magnitudes of the changes in markers of intravascular hemolysis during distance running. fourteen male distance runners (vo2 max = 66.1 +/- 5.0 ml.kg-1.min-1, mean +/- sd) completed two treadmill runs and a resting control procedure. the two treadmill tests involved running at 215 m.min-1 for 10,000 footstrikes at elevations of either +6% (uphill) or -6% (downhill). mean foot impact force was 11% greater with t ... | 2012 | 3366521 |
| hypothyroidism and sex chromosomes. | the observation of campbell and price in 1979 that their unit had diagnosed four subjects with both klinefelter's syndrome and congenital hypothyroidism raised the suspicion of an association between the two conditions. this, and the published reports of an xx male, five xxy males, and one mosaic xy/xxy with congenital or acquired forms of hypothyroidism, together with the higher incidence in women and the absence of sex difference among inherited congenital cases, suggested a possible sex chrom ... | 2005 | 3367350 |
| effect of chronic naltrexone administration and its withdrawal on the regional activity of neurons that contain norepinephrine, dopamine and serotonin. | a method is described that permits the simultaneous quantitation of norepinephrine (ne), dopamine (da) serotonin (5-ht) and their respective major metabolites, 3-methoxy-4-hydroxy phenylglycol (mhpg), 3-methoxytyramine (3-mt), dihydroxyphenyl acetic acid (dopac) and 5-hydroxyindole acetic acid (5-hiaa) in discrete brain regions. the ratio of mhpg/ne, dopac/da and 5-hiaa/5-ht was used to assess the effects of the chronic administration of the narcotic antagonist, naltrexone, and its withdrawal on ... | 1988 | 3370455 |
| activity level in hospitalized children during sleep onset latency. | 2012 | 3370525 | |
| the scoop on sugar. | 2012 | 3371737 | |
| [central pontine myelinolysis following rapid correction of hyponatremia: diagnosis by ct scan]. | 2006 | 3373100 | |
| ischaemia-induced changes in the phosphorylase activity in different parts of the cardiac conduction system. | the phosphorylase specific activity was lowered in total ischaemia in all examined parts of the myocardium and the conduction system of the heart. sixty-minute ischaemia had a considerable effect on glycogen degradation in right bundle branch and in the working myocardium, however, its glycogenolytic effect on the av-node and penetrating bundle of his was insignificant. phosphorylase "a" evaluated as a percentage of the total phosphorylase activity decreased in the working myocardium and increas ... | 1988 | 3391039 |