Publications

TitleAbstractYear(sorted descending)
Filter
PMID
Filter
multispacer typing of rickettsia isolates from humans and ticks in tunisia revealing new genotypes.rickettsioses are important remerging vector born infections. in tunisia, many species have been described in humans and vectors. genotyping is important for tracking pathogen movement between hosts and vectors. in this study, we characterized rickettsia species detected in patients and vectors using multispacer typing (mst), proposed by founier et al. and based on three intergenic spacers (dksa-xerc, rmpe- trna(fmet), mppa-pruc) sequencing.201324380581
rats, cities, people, and pathogens: a systematic review and narrative synthesis of literature regarding the ecology of rat-associated zoonoses in urban centers.urban norway and black rats (rattus norvegicus and rattus rattus) are the source of a number of pathogens responsible for significant human morbidity and mortality in cities around the world. these pathogens include zoonotic bacteria (leptospira interrogans, yersina pestis, rickettsia typhi, bartonella spp., streptobacillus moniliformis), viruses (seoul hantavirus), and parasites (angiostrongylus cantonensis). a more complete understanding of the ecology of these pathogens in people and rats is ...201323590323
murine typhus and leptospirosis presenting with undifferentiated symptoms of an acute febrile illness to waikato hospital, new zealand, 2009-2010.this prospective observational study aimed to identify what proportion of patients presenting to waikato hospital with undifferentiated symptoms of an acute febrile illness (usfi) have leptospirosis or murine typhus infection, and to identify factors at presentation predictive of each infection. it also aimed to identify infecting rickettsial organism(s) causing murine typhus in the region.201323799383
serological evidence for exposure of dogs to rickettsia conorii, rickettsia typhi, and orientia tsutsugamushi in sri lanka.vector-borne rickettsial infection is a major cause of febrile illnesses throughout the world. although vertebrates hosting the vectors play a vital role in the natural cycle of rickettsiae, studies have not been conducted on them in sri lanka. therefore, the present study was designed to determine the exposure of dog population in rajawatta, thambavita, and areas of the western slopes and unawatuna of sri lanka to rickettsial pathogens. a total of 123 dog blood samples were collected from those ...201323930973
rickettsioses in the central hills of sri lanka: serological evidence of increasing burden of spotted fever group.to study the epidemiology, clinical features, and changing pattern of rickettsial infections on the western slopes of the hilly central province of sri lanka over 6 years.201323871280
[management of alcoholism, drug intoxication, and attempted suicide]. 20133845138
murine typhus in humans, yucatan, mexico. 201323735173
murine typhus in tunisia: a neglected cause of fever as a single symptom.we had for aim to describe the epidemiologic and clinic characteristics of murine typhus in a series of 43 serologically confirmed cases, in our region.201323619288
flea-borne rickettsioses in the north of caldas province, colombia.rickettsia typhi and r. felis are the etiological agents of murine typhus and flea-borne spotted fever, respectively. both are emerging acute febrile zoonotic diseases for which fleas are vectors; they also have similar clinical characteristics and global distribution. in 2005, we identified the circulation of murine typhus in 6 towns within the mountainous coffee-growing area north of caldas, colombia. we now report the specific seroprevalence against r. typhi and r. felis, and associated risk ...201323473218
molecular detection of rickettsia typhi in cats and fleas.rickettsiatyphi is the etiological agent of murine typhus (mt), a disease transmitted by two cycles: rat-flea-rat, and peridomestic cycle. murine typhus is often misdiagnosed and underreported. a correct diagnosis is important because mt can cause severe illness and death. our previous seroprevalence results pointed to presence of human r. typhi infection in our region; however, no clinical case has been reported. although cats have been related to mt, no naturally infected cat has been describe ...201323940746
cutaneous leishmaniasis and rickettsial african tick-bite fever: a combination of exotic traveler's diseases in the same patient.cutaneous leishmaniasis and rickettsial african tick-bite fever are two zoonoses increasingly diagnosed in industrialized nations due to more international travel to endemic areas.201222788813
murine typhus: endemic rickettsia in southwest texas.murine typhus is a zoonosis caused by the organism rickettsia typhi and is transmitted to humans by fleas. it is endemic in several areas of texas, california and hawaii where the vector is supported predominantly by rodents in addition to opossums, domestic and feral cats and domestic dogs. we present a typical case in an adult from corpus christi, located in one of the four endemic areas in texas. included is an overview of the organism's pathogenicity and our host responses, both influencing ...201222693777
[rickettsiosis is a neglected cause of fever in returned travellers].we present two cases of rickettsial infections in travellers caused by rickettsia typhi and r. africae respectively. the two cases illustrate the widely varying symptomatology and aetiology. incidence and treatment of the disease are discussed. the diagnosis is complex, and we believe that rickettsiosis is an underestimated cause of fever in returned travellers from the tropics. in the past two years only 26 cases have been diagnosed in denmark. whenever rickettsiosis is clinically suspected, em ...201222668648
murine typhus in returned travelers: a report of thirty-two cases.murine typhus, caused by rickettsia typhi and transmitted mainly by the rat fleas, xenopsylla cheopis, has emerged in the field of travel medicine. we analyzed retrospectively the epidemiological, clinical, and biological characteristics of the 32 murine typhus cases that were diagnosed during the past 3 years at the world health organization collaborative center for rickettsial diseases, marseille, france. all of the cases occurred in travelers and most of them had returned from africa (n = 13 ...201222665617
rickettsia typhi. a new causative agent of round pneumonia in adults. 201222503113
dose-response model of murine typhus (rickettsia typhi): time post inoculation and host age dependency analysis.rickettsia typhi (r. mooseri) is the causative agent of murine typhus. it is one of the most widely distributed flea-borne diseases with a relatively mild febrile initial illness with six to 14 days of incubation period. the bacterium is gram negative and an obligate intracellular pathogen. the disease is transmitted to humans and vertebrate host through fleabites or via contact with infected feces. this paper develops dose-response models of different routes of exposure for typhus in rodents.201222462408
murine typhus: clinical and epidemiological aspects.is an intracellular bacteria who causes murine typhus. his importance is reflected in the high frequency founding specific antibodies against rickettsia typhi in several worldwide seroepidemiological studies, the seroprevalence ranging between 3-36%. natural reservoirs of r. typhi are rats (some species belonging the rattus genus) and fleas (xenopsylla cheopis) are his vector. this infection is associated with overcrowding, pollution and poor hygiene. typically presents fever, headache, rash on ...201224893060
a medical center-based tertiary reference laboratory. experience at mayo medical laboratories (mml). 20123415449
hematological effect of supplementing anemic children with vitamin a alone and in combination with iron.ninety-nine anemic children aged 1-8 y were divided into four groups. each group was supplemented for 2 mo with vitamin a, iron, vitamin a plus fe, or a placebo. clinical, hematological, and fe biochemical evaluations were performed at the beginning and end of the study. vitamin a supplementation produced significant elevations in the serum levels of retinol, blood hemoglobin, hematocrit, erythrocytes, serum fe, and percent transferrin saturation (%ts) and had no effect on total fe binding capac ...20123414574
spider bites.spiders are a ubiquitous component of the fauna of north america. at least 50 to 60 species in the united states are known to bite humans, although in most cases, the diagnosis is never suspected nor is treatment necessary. a few species of spiders are capable of causing necrotic wounds and, occasionally, death. this review is intended to provide an overview of the recent advances in the diagnosis and treatment of spider bites, as well as a compilation of the many species of spiders that have be ...20123541795
korean elders in the united states: intergenerational relations and living arrangements. 20123557149
cheilitis glandularis: a case affecting the upper lip.cheilitis glandularis is a rare disorder characterized by enlarged mucous glands, usually in the lower lip, and possibly predisposing to squamous cell carcinoma. a case affecting the upper lip is presented, which appears to be the first report of the disorder in that site.20123467290
[a triple av nodal pathway in methionine poisoning: the role of atropine in the induction of supraventricular tachycardia]. 20123414037
activity level in hospitalized children during sleep onset latency. 20123370525
foot impact force and intravascular hemolysis during distance running.this study was designed to examine the relationship between foot impact force and the magnitudes of the changes in markers of intravascular hemolysis during distance running. fourteen male distance runners (vo2 max = 66.1 +/- 5.0 ml.kg-1.min-1, mean +/- sd) completed two treadmill runs and a resting control procedure. the two treadmill tests involved running at 215 m.min-1 for 10,000 footstrikes at elevations of either +6% (uphill) or -6% (downhill). mean foot impact force was 11% greater with t ...20123366521
haemorrhagic shock with paradoxical bradycardia. 20123403782
the current status of panoramic radiography.the current status of dental panoramic tomography (rotational panoramic radiography) is reviewed. this technique is based on a combination of tomography and slit-beam radiography to provide an image of both jaws on a single film. there is a greater degree of image degradation when compared with conventional radiographic techniques due to tomographic blurring, magnification and distortion, secondary images and burn-out. meticulous patient position is essential to accommodate their jaws to the ima ...20123294598
acute rheumatic fever in new york city. 20123405514
[tumor necrosis factor]. 20123310111
a request for hormone replacement therapy. 20123255965
bloodstream infection among children presenting to a general hospital outpatient clinic in urban nepal.there are limited data on the etiology and characteristics of bloodstream infections in children presenting in hospital outpatient settings in south asia. previous studies in nepal have highlighted the importance of murine typhus as a cause of febrile illness in adults and enteric fever as a leading bacterial cause of fever among children admitted to hospital.201223115652
detection of rickettsia spp. and host and habitat associations of fleas (siphonaptera) in eastern taiwan.rickettsia typhi and rickettsia felis (rickettsiales: rickettsiaceae) are two rickettsiae principally transmitted by fleas, but the detection of either pathogen has rarely been attempted in taiwan. of 2048 small mammals trapped in eastern taiwan, apodemus agrarius pallas (24.5%) and mus caroli bonhote (24.4%) (both: rodentia: muridae) were the most abundant, and m. caroli hosted the highest proportion of fleas (63.9% of 330 fleas). two flea species were identified: stivalius aporus jordan and ro ...201222390200
surface proteome analysis and characterization of surface cell antigen (sca) or autotransporter family of rickettsia typhi.surface proteins of the obligate intracellular bacterium rickettsia typhi, the agent of murine or endemic typhus fever, comprise an important interface for host-pathogen interactions including adherence, invasion and survival in the host cytoplasm. in this report, we present analyses of the surface exposed proteins of r. typhi based on a suite of predictive algorithms complemented by experimental surface-labeling with thiol-cleavable sulfo-nhs-ss-biotin and identification of labeled peptides by ...201222912578
tolc-dependent secretion of an ankyrin repeat-containing protein of rickettsia typhi.rickettsia typhi, the causative agent of murine (endemic) typhus, is an obligate intracellular pathogen with a life cycle involving both vertebrate and invertebrate hosts. in this study, we characterized a gene (rt0218) encoding a c-terminal ankyrin repeat domain-containing protein, named rickettsia ankyrin repeat protein 1 (rarp-1), and identified it as a secreted effector protein of r. typhi. rt0218 showed differential transcript abundance at various phases of r. typhi intracellular growth. ra ...201222773786
[medium-term results of radial keratotomies and discussion]. 20123269275
two pathogens and one disease: detection and identification of flea-borne rickettsiae in areas endemic for murine typhus in california.results of an environmental assessment conducted in a newly emergent focus of murine typhus in southern california are described. opossums, didelphis virginiana kerr, infested with cat fleas, ctenocephalides felis buché, in the suburban area were abundant. animal and flea specimens were tested for the dna of two flea-borne rickettsiae, rickettsia typhi and rickettsia felis. r. felis was commonly detected in fleas collected throughout this area while r. typhi was found at a much lower prevalence ...201223270180
francisco de santillana: first veterinary practitioner in north america? 20123533868
oral biopsy technique. the pathologist's perspective. 20123524767
prolonged control of increased intracranial pressure with glycerin. 20125049685
murine typhus: an important consideration for the nonspecific febrile illness.murine typhus is a widely distributed flea-borne infection caused by rickettsia typhi. symptoms of murine typhus are nonspecific and mimic a variety of other infectious diseases. we herein report a case of murine typhus in an area where the broad use of ddt in the mid-20th century has now made it a rare disease. the patient described presented with headache, fever, and a faint macular rash. initial laboratory studies revealed a slight transaminase elevation. further questioning revealed exposure ...201223326268
modification of the response to opioid and nonopioid drugs by chronic opioid antagonist treatment.chronic exposure to opioid antagonists increases the analgesic actions of opioids such as morphine. in the present studies, morphine's analgesic potency was increased (supersensitivity) following an 8 day subcutaneous naltrexone implant in mice, but not following a 1 day implant. supersensitivity was maximal 24hr following the 8 day implant and declined linearly and had returned to control levels by 120hr. implantation of naltrexone pellets for 8 days was found to increase the relative analgesic ...20123362035
'treatment ind' is an oxymoron. 20123352116
Transmission of flea-borne zoonotic agents (*).Flea-borne zoonoses such as plague (Yersinia pestis) and murine typhus (Rickettsia typhi) caused significant numbers of human cases in the past and remain a public health concern. Other flea-borne human pathogens have emerged recently (e.g., Bartonella henselae, Rickettsia felis), and their mechanisms of transmission and impact on human health are not fully understood. Our review focuses on the ecology and epidemiology of the flea-borne bacterial zoonoses mentioned above with an emphasis on rece ...201221888520
the role of dogs in the eco-epidemiology of rickettsia typhi, etiological agent of murine typhus.rickettsia typhi, etiological agent of murine typhus (mt), is transmitted to humans from an animal reservoir through two cycles: a classic rat-flea-rat cycle, and a peridomestic animal cycle. there are not many studies concerning which animals are involved in the peridomestic cycle, and most of them are focused on cats. the aim of this study was to determine the presence of r. typhi in dogs, not only by serological methods but also by direct methods such as culture and molecular detection. two h ...201223290118
hypophosphatemia-associated respiratory muscle weakness in a general inpatient population.although hypophosphatemia has been implicated as a cause of respiratory failure, its impact on respiratory muscle function in patients hospitalized for other reasons remains to be determined. maximal inspiratory pressures (mip) and maximal expiratory pressures (mep) were measured at the bedside in 23 hospitalized patients with serum phosphate levels less than 2.5 mg/dl, and these measurements were repeated daily during phosphate repletion until serum phosphate levels reached the normal range. a ...20123364446
[epidemiology of dental caries and periodontal disease in guatemala]. 20123269012
rickettsia felis infections, new zealand.to the editor: members of the genus rickettsia have garnered much attention worldwide in recent years with the emergence of newly recognized rickettsioses. in new zealand, only rickettsia typhi and r. felis, belonging to the typhus and spotted fever groups, respectively, have so far been found (1). r. typhi, primarily transmitted by the oriental rat flea (xenopsylla cheopis), has a worldwide distribution and causes murine typhus in humans (2). at the end of 2009, a total of 47 cases of murine ty ...201222261304
investigation of an outbreak of rickettsial febrile illness in guatemala, 2007.we describe an outbreak of spotted fever group (sfg) rickettsiosis that occurred in 2007 in a farming community in southeastern guatemala. we identified 17 cases of an acute febrile illness, among which 10, including two fatalities, were confirmed or probable cases of rickettsial disease (case-fatality proportion 12%).201223266334
focal dermal hypoplasia syndrome (goltz syndrome): the first dental case report. 20123466146
radiographic anatomy of the calcaneus. part iii: superior surface. 20123430354
[kidney concentrating ability in children and adolescents with normal kidneys]. 20123398393
the scoop on sugar. 20123371737
the illusion of catch-up growth in premature infants. use of the growth index and age correction.growth data of 61 premature infants who were observed for 29 months were analyzed to determine if there is validity to the concept of catch-up growth. weight, length, and head circumference were recorded at each visit. for each measurement, a growth index was calculated to facilitate comparison of infants of different ages and sexes. the age of a child at each visit was also corrected for prematurity by subtracting the number of weeks premature from the postnatal chronological age to generate a ...20123578164
[analysis of the health and social status of 50 very old patients]. 20123442863
[prognostication of the outcome of traumatic disease and the optimal therapy at the initial period]. 20123247108
[clinical study of cefmenoxime in thoracic surgery. transfer of cefmenoxime to lung tissue and pleural fluid and prophylaxis of postoperative infections].twenty-six patients who underwent pulmonary resection for the lung disease were administered 1 g of cefmenoxime (cmx) by intravenous drip infusion just before the operation. the cmx levels in the serum, lung tissue and pleural fluid were measured using the agar-well technique. the effect of the drug on the prophylaxis of postoperative infections was investigated. the obtained results are summarized as follows; 1. the peak concentration of cmx in the serum was 58.23 micrograms/ml 1 hour after sta ...20123480362
pathological hyperprolactinemia suppresses hot flashes in menopausal women.hyperprolactinemia impairs pituitary-gonadal function in young women, but its effect in menopausal women is not known. the purpose of this report is to describe the effect of hyperprolactinemia on gonadotropin secretion and hot flashes in menopausal women before and after treatment with a dopamine agonist. we studied two such women with prolactinomas. both had plasma lh and fsh levels in the range found in premenopausal women and no hot flashes. treatment with bromocriptine was associated with n ...20123346363
[somatic effects of radiation]. 20123254662
"where" and "what" in vision.the mixture of a few horizontal and vertical line segments embedded in an aggregate of diagonal line segments can be rapidly counted and their positions rapidly determined by a parallel (preattentive) process. however, the discrimination between horizontal and vertical orientation (that is, discrimination of a single conspicuous feature) requires serial search by focal attention. under recent theories of attention, focal attention has been assumed to be required for the recognition of different ...20124001937
present criteria for the diagnosis of in vivo of olivopontocerebellar atrophy.we present 6 cases of olivopontocerebellar atrophy (opca) of dèjérine-thomas type. the diagnosis was based on an appropriate clinical picture, anomalous brainstem auditory evoked potentials (baep) and computerized tomography (ct) and/or magnetic nuclear resonance (mnr) imaging which demonstrated atrophy of the cerebellum and the pons. we believe that these methods will provide greater uniformity in the diagnosis of such an heterogeneous entity as opca.20113163874
[value of determining myoglobin and creatine phosphokinase levels in the evaluation of the cardiovascular status in children with acute pneumonia]. 20113205644
studies on the effect of long-term use of low dose aspirin in kawasaki disease. 20113148261
aflatoxins in the livers of children with kwashiorkor in ghana.autopsy liver specimens from 22 kwashiorkor children in ghana were analysed for the presence of aflatoxins using both high performance liquid chromatography and thin layer chromatography. aflatoxin b1 was found in the livers of 20 subjects and aflatoxicol in the livers of the remaining two subjects. these results confirm previous findings of aflatoxin b1 and aflatoxicol in the livers of children with kwashiorkor and provide further evidence of associations between these toxic compounds and kwash ...20113092419
tripelennamine enhances buprenorphine-, but not pentazocine-induced hyperactivity in mice.the opioid agonist-antagonist pentazocine (1-30 mg/kg) and the partial agonist buprenorphine (0.05-0.25 mg/kg) were tested, alone or in combination with the histamine h1-receptor antagonist tripelennamine (1, 2.5, 5 or 10 mg/kg), on locomotor activity in mice of the cd-1 strain. when given alone, pentazocine produced slight and non-dose-related activity increments, while buprenorphine induced strong and dose-related locomotor stimulation. tripelennamine slightly increased activity by itself and ...20113137594
[contribution of phlebography in the surgical treatment of chronic venous insufficiency of the lower extremities].in which circumstances does a surgeon request phlebograms and which ones? what is the contribution of phlebography regarding therapeutic indications and surgical technique.20113043471
coagulation and inflammation in scrub typhus and murine typhus-a prospective comparative study from laos.clin microbiol infect abstract: scrub typhus (caused by orientia tsutsugamushi) and murine typhus (caused by rickettsia typhi) cause up to 28% of febrile episodes in thailand and laos. the current understanding of coagulation and inflammation in the pathogenesis of these clinically very similar vasculotropic diseases is limited. this study compared human in vivo changes in 15 coagulation, inflammation and endothelial activation markers in prospectively collected admission and follow-up samples o ...201122192733
development of a duplex real-time pcr for the detection of rickettsia spp. and typhus group rickettsia in clinical samples.molecular diagnosis using real-time polymerase chain reaction (pcr) may allow earlier diagnosis of rickettsiosis. we developed a duplex real-time pcr that amplifies (1) dna of any rickettsial species and (2) dna of both typhus group rickettsia, that is, rickettsia prowazekii and rickettsia typhi. primers and probes were selected to amplify a segment of the 16s rrna gene of rickettsia spp. for the pan-rickettsial pcr and the citrate synthase gene (glta) for the typhus group rickettsia pcr. analyt ...201122098502
case report: severe typhus group rickettsiosis complicated by pulmonary edema in a returning traveler from indonesia.we report a severe case of typhus group rickettsiosis in a returning traveler from indonesia. this typically mild illness was characterized by progressive pulmonary edema and prolonged fever, with defervescence 4 days after the commencement of doxycycline.201122144455
murine typhus returns to new south wales: a case of isolated meningoencephalitis with raised intracranial pressure.murine typhus (mt) occurs worldwide, but, in australia, is only regularly diagnosed in south-west western australia. meningoencephalitis is an uncommon complication of mt, often accompanied by rash or systemic involvement. we report a case of mt presenting exclusively with meningoencephalitis, raised intracranial pressure, papilloedema and bilateral 6th cranial nerve palsies. mt should be considered in patients with "aseptic" meningitis or meningoencephalitis, even in the absence of other typica ...201121692726
serum free thyroxine and free tri-iodothyronine in normal children.serum free thyroxine (ft4) and free tri-iodothyronine (ft3) were measured in 138 normal school children, adolescents and their younger siblings, whose ages ranged from 3 months to 18 years. mean ft4 concentration (16.8 pmol/l) was similar to the adult mean concentration of 17 pmol/l and all the values were within the adult reference range. at all ages the ft3 range was considerably higher than the adult reference range and the overall mean ft3 concentration (8.3 pmol/l) was at the upper limit of ...20113232955
training of general practitioners in interpreting chest radiographs.easily accessible chest and skeleton roentgen examinations are needed in primary health care. in finland the health centres perform about a third of all roentgen examinations. many of the films are interpreted by health centre doctors at least in the primary phase. about 40% of them are chest radiographs. in 2640 chest radiographs interpreted by general practitioners the final roentgen diagnosis was pathological in 54%. pathological conditions were totally overlooked in 13%. of normal cases 19% ...20113205199
[asymptomatic myocardial ischemia: which tests? which treatment?]. 20113219450
intravenous indomethacin for postoperative pain. a double-blind study of ankle surgery.intravenous indomethacin infusion (75 mg/10 h) for relief of pain after ankle surgery was compared with placebo in a double-blind study. ninety-seven patients were operated on for a malleolar fracture or ruptured ligament of the ankle under single-dose spinal anesthesia. in the indomethacin group, 14 out of 49 patients were free from pain, 4/47 in the control group. severe pain was experienced by 24/49 in the indomethacin group and by 41/47 in the control group. supplementary intramuscular oxyco ...20113128054
seroprevalence of rickettsia typhi and rickettsia conorii infections in the canary islands (spain).objective: the aim of this work was to evaluate the prevalence of past infection due to rickettsia typhi and rickettsia conorii in the canary islands (spain). methods: a representative sample of the population of the seven islands, formed of 662 people aged between 5 and 75 years (368 females, 294 males), was analyzed. epidemiological data were obtained by direct survey. the detection of serum igg antibodies against both microorganisms was based on an indirect immunofluorescence test, considered ...201121612963
[gastric carcinoid associated with duodenal diverticulum]. 20113121905
ovarian carcinoma: abdominopelvic irradiation following reexploration.twenty patients with ovarian cancer, who following reexploration were left with residual disease nodules of less than 2 cm diameter, received abdominopelvic irradiation. of these patients 18 had previous chemotherapy. fifteen patients completed treatment, 13 of whom had prior chemotherapy. six of the 18 patients with invasive tumors were alive and disease free 18-53 months postradiotherapy, while only 4 patients had died at the time of follow-up. no patient with residual nodules greater than 1 c ...20113141249
[primary transport of acute patients. optimal use of rescue resources exemplified by the canton of graubünden]. 20113927607
widespread use of real-time pcr for rickettsial diagnosis.we report 2 years of experience with rickettsial molecular diagnosis using real-time pcr at the french national reference center. all rickettsia genomes available were compared to discover specific sequences to design new sets of primers and probes. the specificity was verified in silico and against a panel of 30 rickettsial species. sensitivity was determined using 10-fold serial dilutions. finally, primers and probes that were both specific and sensitive were routinely used for the diagnosis o ...201122092999
bilateral simultaneous facial palsy following scrub typhus meningitis: a case report and literature review.scrub typhus is widely distributed across the asia-pacific region, taiwan included. the clinical manifestations and complications of scrub typhus vary and the illness ranges in severity from mild to fatal. the etiology of facial nerve palsy varies and infectious agents have been associated with this condition. rickettsiae species have, however, rarely been reported as the causative agents. we report the case of a 49-year-old man who had fever, malaise, headache, oligouria and tea-colored urine. ...201122208541
a cluster of pediatric endemic typhus cases in orange county, california.murine typhus is typically a mild febrile illness caused by rickettsia typhi, generally con?ned to texas and southern california. clinicians should consider early treatment with doxycycline when presented with a child having protracted fever, rash, and headache.we present 5 pediatric cases and a literature review highlighting the changing epidemiology and diagnostic dif?culty of typhus.201121298850
[bilateral anterior uveitis and rickettsia typhi infection]. 201121324556
structural features of lipid a-áof rickettsia typhi.lipid a isolated from the rickettsia typhi lipopolysaccharide (lps) was investigated for its composition and structure using chemical analyses, gas chromatography-mass spectrometry (gc-ms), and electrospray ionization (esi) combined with the tandem mass spectrometry (ms/ms). our studies revealed a noticeable compositional and structural heterogeneity of lipid a with respect to the content of phosphate groups and the degree of acylation. it appeared that at least two molecular species were presen ...201121434703
[an outbreak of endemic typhus in baoshan city, yunnan province.]objective: to understand the epidemiologic characteristics of endemic typhus in baoshan city. methods: epidemiological data were collected and characteristics were analyzed. igg antibody (ab) of rickettsia mooseri and orientia tsutsugamushi in serum of patients were tested using both weil-felix and ifa method. the rickettsia mooseri glta gene, rickettsia prowazekii glta gene, orientia tsutsugamushi 56 kda protein gene, sfgr ompa gene, ehrlichia sp. 16s rrna gene and anaplasma sp. 16s rrna gene i ...201121518541
detection of rickettsia felis and rickettsia typhi and seasonal prevalence of fleas collected from small mammals at gyeonggi province in the republic of korea.abstract fleas were collected from live-captured small mammals to identify flea-borne pathogens, host associations, and seasonal prevalence of flea species, as part of the 65th medical brigade rodent-borne disease surveillance program at 20 military installations and training sites, gyeonggi province, republic of korea, 2005-2007. a total of 1251 fleas were recovered from 2833 small mammals. apodemus agrarius, the striped field mouse, accounted for 93.1% (2,637/2,833) of all small mammals captur ...201121612536
q fever, spotted fever group, and typhus group rickettsioses among hospitalized febrile patients in northern tanzania.background. the importance of q fever, spotted fever group rickettsiosis (sfgr), and typhus group rickettsiosis (tgr) as causes of febrile illness in sub-saharan africa is unknown; the putative role of q fever as a human immunodeficiency virus (hiv) coinfection is unclear. methods. we identified febrile inpatients in moshi, tanzania, from september 2007 through august 2008 and collected acute- and convalescent-phase serum samples. a ≥4-fold increase in immunoglobulin (ig) g immunfluorescence ass ...201121810740
investigation of anaplasmosis in yiyuan county, shandong province, china.to investigate the situation of anaplasmosis in yiyuan county, shandong province.201121803311
postinfectious optic neuropathy in endemic typhus.endemic typhus (rickettsia typhi), also known as murine typhus, is a flea-borne bacterial disease rarely found in most of the developed world. known ocular manifestations linked to endemic typhus include mild vitritis, retinal lesions, and retinal vascular leakage. optic neuropathy, however, is rarely associated with r. typhi, and postinfectious optic neuropathy is even less common. to highlight this unusual complication, we report a patient who developed postinfectious optic neuropathy a few we ...201121897295
[x-ray computed tomography in venous pathology].after presenting the tomodensitometric semiology of venous thromboses in various territories, the authors define its indications. it is essentially in deep territories, head, chest and abdomen that the ct-scan is used to study and diagnose unrecognized thromboses as well as determine the venous repercussion of various neighboring ailments. the respective place of the ct-scan, ultrasonography and various phlebographies is analyzed.20113043474
protein candidates for the serodiagnosis of rickettsioses.the laboratory diagnosis of rickettsioses is based on serology (reference method), cell culture and/or molecular tools. however, the main drawback of serology is its incapacity to provide identification of rickettsiae at the level of species. the aim of this study was to propose the versatile protein markers able to discriminate the patients with murine typhus from those with mediterranean spotted fever. we have cloned and expressed 20 proteins of rickettsia prowazekii and rickettsia rickettsii, ...201122098357
regulation of ige synthesis in atopic disease. 20113125207
positive correlation between the level of protein-carboxyl methylase in spermatozoa and sperm motility.levels of protein-carboxyl methylase (pcm) activity were measured in spermatozoa from infertile patients with less than 50% sperm motility and compared with those of normal fertile controls. when spermatozoa were washed by a standard centrifugation procedure, the level of pcm activity in a subgroup of patients with sperm motility ranging from 0% and 20% (24.0 +/- 5.2 pmol/mg protein, mean +/- standard error of the mean) was significantly different from that of controls (35.9 +/- 2.3 pmol/mg). ho ...20113086132
Murine typhus in the homeless.Homeless populations are particularly exposed to many vector-borne diseases because of their poor living conditions. We tested sera from 299 homeless people recruited in 2010 and 2011 in Marseilles, France for antibodies to Rickettsia typhi by microimmunofluorescence using a titer of 1:25 as a cut-off titer, and we confirmed the results by Western blot and cross-adsorption studies. Sixty-three persons (22%) had antibodies against R. typhi. The murine typhus seroprevalence rates have significantl ...201122093517
[gastroenteritis with fever, headache and rash after travelling in india].a 63-year-old patient presented to our emergency unit two days after returning from india suffering from watery diarrhea, nausea, fever and headache. on admission we found a maculopapular rash on his trunk and forehead. laboratory findings revealed a leuko-thrombopenia and elevated levels of crp and procalcitonin. we started treatment with ciprofloxacin. after 48 hours of treatment the diarrhea subsided, whereas the rush on his trunk increased. under the suspicion of rickettsial fever we started ...201120945058
[sero-epidemiological investigation on rickettsia typhi, bartonella henselae and orientia tsutsugamushi in farmers from rural areas of tianjin, 2007 - 2009.]objective: to study the sero-epidemiological status regarding rickettsia (r.) typhi, bartonella (b.) henselae and orientia (o.) tsutsugamushi in farmers from rural areas of tianjin. methods: field epidemiological surveys were performed in 8 districts (county) of tianjin city from 2007 to 2009. 886 farmers were randomly recruited and their serum samples collected to detect the specific antibodies of r. typhi, b. henselae and o. tsutsugamushi by micro-indirect immunoflorescence (ifa). results: the ...201121457660
a prolonged decline in the incidence of necrotizing enterocolitis after the introduction of a cautious feeding regimen. 20113144829
[accuracy of fit of castings in relation to impression, model and technical parameters]. 20113044749
sulbactam plus ampicillin: interim review of efficacy and safety for therapeutic and prophylactic use.the efficacy and safety of sulbactam/ampicillin has been evaluated in 39 studies of therapeutic use and six studies of prophylaxis. studies of therapy were conducted in 899 patients: 751 seriously ill, many of whom had multiple concurrent diseases, and 148 with gonorrhea. overall clinical and bacteriologic success was achieved in 92% of assessable cases; 88% of 768 pathogens in these patients were eradicated. of these pathogens, 43% were resistant to ampicillin; eradication rates of 91% and 85% ...20113026019
[two travellers suffering from typhus].endemic typhus, caused by rickettsia typhi, belongs to the typhus group of the rickettsioses. the disease is prevalent worldwide and is probably an underestimated cause of illness accompanied by fever in travellers, due to its frequently mild presentation and resemblance to diseases like typhoid- or dengue fever. broad-spectrum antibiotics are not effective in the treatment of endemic typhus, but the disease is responsive to doxycycline.201122217240
cyclophosphamide-induced liver necrosis: a possible interaction with azathioprine.cyclophosphamide is a valuable drug for the treatment of vasculitis and hepatic toxicity resulting from its use has been reported rarely. we describe four patients in whom cyclophosphamide was associated with liver injury when its administration had been preceded by azathioprine. microscopy of hepatic biopsy material in three of these cases showed liver cell necrosis. in two of the patients, cyclophosphamide had been given previously without earlier azathioprine and hepatic damage had not been n ...20113060893
clinical evaluation of ocular and visual functions in insulin-dependent juvenile diabetics.ocular and visual functions were evaluated in 30 insulin-dependent diabetics, aged 12 to 20 years, and 30 age- and sex-matched nondiabetics. the test and control groups were compared in terms of visual resolution, accommodative ability, color discrimination, functional retinal reserve, and afferent optic nerve function. these results were considered along with the blood-glucose level, crystalline lens, fundus appearance, level of diabetic control, and disease duration. no widespread differences ...20113740205
Refresh
firstprev
12345678910...
nextlast
Displaying items 201 - 300 of 1111