| [cat scratch disease]. | | 1999 | 10088350 |
| [bartonellosis]. | | 1999 | 10088493 |
| ocular manifestation of systemic infections. | patients with various systemic infections can often be diagnosed on the basis of their presenting ocular signs and symptoms. recognition of the ocular manifestations of systemic infections will expedite diagnosis and allow rapid institution of appropriate therapy thereby reducing morbidity and mortality. recent literature discussing ophthalmologic findings in the following diseases are reviewed: whipple's disease, endogenous endophthalmitis, cat-scratch disease, toxoplasmosis, and hepatitis c. | 1995 | 10160425 |
| prevalence of bartonella henselae immunoglobulin g antibodies in singaporean cats. | bartonella henselae causes several clinical diseases in humans. the most common infection is the classical cat-scratch disease (csd) occurring in immunocompetent and immunocompromised children exposed to newly acquired kittens. this is the first study of b. henselae infection in singaporean cat population. | 1999 | 10093952 |
| [trench fever]. | | 1999 | 10201203 |
| clinical and pathologic evaluation of chronic bartonella henselae or bartonella clarridgeiae infection in cats. | human bartonella infections result in diverse medical presentations, whereas many cats appear to tolerate chronic bacteremia without obvious clinical abnormalities. eighteen specific-pathogen-free cats were inoculated with bartonella henselae- and/or bartonella clarridgeiae-infected cat blood and monitored for 454 days. relapsing bacteremia did not correlate with changes in protein profiles or differences in antigenic protein recognition. intradermal skin testing did not induce a delayed type hy ... | 1999 | 10203518 |
| evaluation of human seroreactivity to bartonella species in sweden. | among the species that compose the expanding genus bartonella, thus far only b. henselae and b. quintana have reportedly been isolated from humans in europe. to evaluate the prevalence of bartonella infection in sweden, we conducted a retrospective serological examination of 126 human serum samples. these samples were analyzed for antibodies to b. henselae, b. quintana, and b. elizabethae. serum samples from 100 blood donors, who spanned the ages of 20 to 60 and had no apparent clinical signs of ... | 1999 | 10203491 |
| [three children with systemic cat scratch disease]. | three girls with systemic cat scratch disease, aged 10, 13 and 9 years, were reported. they presented a prolonged fever and back pain in the early stage of the disease, and had no regional lymphadenopathy. two of them had hepatosplenic granulomas, one with multiple 5 mm hypoechoic lesions in the liver and spleen, and the other with a single 2.5 cm hypodense lesion in the left hepatic lobe. the latter patient underwent a partial left hepatic lobectomy. all patients had elevated titers of antibodi ... | 1999 | 10222672 |
| bartonella spp infection as a possible cause of uveitis in a cat. | a 6-year-old castrated mixed-breed cat was evaluated because of unilateral anterior uveitis. the cat was seronegative for antibodies to toxoplasma gondii, coronaviruses, and feline immunodeficiency virus, and antigens for felv p27 and cryptococcus neoformans. antibodies to bartonella spp were detected in serum and aqueous humor. the antibody coefficient (c value) for igg antibodies to bartonella spp in the aqueous humor was 4.42; values > 1 suggest ocular production of antibodies and supports a ... | 1999 | 10212684 |
| paronychia caused by bartonella henselae. | | 1997 | 10213558 |
| serologic response to bartonella henselae in patients with cat scratch disease and in sick and healthy children. | indirect fluorescent antibody assay (ifa) is the most reliable test for detecting antibody to bartonella henselae in the diagnosis of cat scratch disease (csd). recently, an elisa test has been proposed, but conflicting results are reported. we compared igg-ifa and igg-igm elisa methods in csd patients and in healthy children. we also tested elisa specificity in a large group of healthy controls and in children with lymphoma-associated lymphadenopathy and with pyogenic lymphadenitis. the elisa p ... | 1999 | 10229038 |
| experimental infection of cotton rats with three naturally occurring bartonella species. | the kinetics of infection and humoral immune response of laboratory-bred cotton rats (sigmodon hispidus) challenged with three bartonella spp. recovered from the blood of naturally infected cotton rats captured in georgia (usa) are described. bartonella spp. infection, as determined by bacteremia, occurred in all 18 cotton rats inoculated with live bartonella of each species at either a low dose, 10(3) colony-forming units (cfu's), or high dose, 10(7) cfu. cotton rats inoculated with lower doses ... | 1999 | 10231754 |
| culture of bartonella quintana and bartonella henselae from human samples: a 5-year experience (1993 to 1998). | bartonella quintana and bartonella henselae are fastidious gram-negative bacteria responsible for bacillary angiomatosis, trench fever, cat scratch disease, and endocarditis. during a 5-year period, we received 2,043 samples for culture of bartonella sp. we found bartonella sp. to be the etiologic agent in 38 cases of endocarditis, 78 cases of cat scratch disease, 16 cases of bacteremia in homeless people, and 7 cases of bacillary angiomatosis. we correlated the results of positive cultures with ... | 1999 | 10325344 |
| cat-scratch disease simulating a malignant process of the chest wall. | cat-scratch disease is a well-known cause of regional adenopathy in immunocompetent children. rarely, patients may present with symptoms simulating a neoplastic disease. the case of a 12-year-old boy with fever, swelling of the chest wall and hepatosplenic nodules is reported. histological analysis of biopsy specimen obtained from the chest wall lesion and the liver revealed granulomatous reaction without malignant cells. serological investigations were positive for bartonella species. the sympt ... | 1999 | 10333124 |
| culture-positive bartonella quintana endocarditis. | a 50-year-old alcoholic man with a 1-year history of pyrexia of unknown origin was admitted with symptoms of endocarditis. large vegetations on his mitral and aortic valve were found on echocardiography. using the bactec 9240 system. bartonella quintana could be grown from two culture sets of blood collected before the start of antimicrobial therapy. this is the first case report of culture-proven bartonella infection in the uk. and is noteworthy because bartonella quintana was detected in conve ... | 1999 | 10219581 |
| cat-scratch disease encephalopathy: a cause of status epilepticus in school-aged children. | we describe 6 school-aged patients who presented with status epilepticus (se) secondary to cat-scratch disease (csd) encephalopathy to alert clinicians to this distinctive clinical entity. the hospital database for admissions during 1 year was reviewed for patients presenting with se; 4 of 5 previously healthy school-aged children with se had csd encephalopathy based on elevated indirect fluorescent antibody titers to bartonella henselae. csd encephalopathy should be included in the differential ... | 1999 | 10228301 |
| disseminated bartonella infection with granulomatous hepatitis in a liver transplant recipient. | disseminated infection with bartonella spp with granulomatous hepatitis was diagnosed in a liver transplant recipient presenting with fever of unknown origin. pathological findings on liver biopsy were atypical, with scant granulomas seen only after a second biopsy. the patient responded promptly to antibiotic therapy. infections caused by bartonella spp should be considered in transplant recipients with fever of unknown origin. | 1999 | 10226118 |
| development and evaluation of a polymerase chain reaction assay using the 16s rrna gene for detection of eperythrozoon suis infection. | the 16s ribosomal rna (rrna) gene of eperythrozoon suis was amplified using gene-specific primers developed from genbank sequence accession u88565. the gene was subsequently cloned and sequenced. based on these sequence data, 3 sets of e. suis-specific primers were designed. these primers selectively amplified 1394, 690, and 839 base-pair (bp) fragments of the 16s rrna gene from dna of e. suis extracted from the blood of an experimentally infected pig during a parasitemic episode. no polymerase ... | 1999 | 10353353 |
| survey of bartonella species infecting intradomicillary animals in the huayllacallán valley, ancash, peru, a region endemic for human bartonellosis. | the natural cycle of bartonella bacilliformis remains uncertain, and the suspected existence of animal reservoirs for the bacterium has never been convincingly demonstrated. we conducted a survey of bartonella species infecting intradomicillary animals in a bartonellosis-endemic region of peru, obtaining blood from 50 animals living in the homes of 11 families whose children had recently had bartonellosis. bartonella-like bacteria were recovered from four of nine small rodents included in the st ... | 1999 | 10344656 |
| acute clinical disease in cats following infection with a pathogenic strain of bartonella henselae (lsu16). | bartonella henselae is the causative agent of human cat scratch disease as well as several serious sequelae of infections, including bacillary angiomatosis and bacillary peliosis. conflicting reports describe the pathogenesis of b. henselae in the cat. in this study, we characterized a strain of b. henselae termed lsu16. this strain was isolated on rabbit blood agar from a naturally infected 10-month-old female cat during a recurrent episode of bacteremia. the bacterial species was confirmed by ... | 1999 | 10338522 |
| detection and identification of ehrlichia, borrelia burgdorferi sensu lato, and bartonella species in dutch ixodes ricinus ticks. | a sensitive and specific pcr hybridization assay was developed for the simultaneous detection and identification of ehrlichia and borrelia burgdorferi sensu lato. in separate assays the 16s rrna gene of ehrlichia species and the 23s-5s rrna spacer region of b. burgdorferi sensu lato were amplified and labeled by pcr. these pcr products were used in a reverse line blot hybridization assay in which oligonucleotide probes are covalently linked to a membrane in parallel lines. hybridization of the s ... | 1999 | 10364588 |
| bartonella henselae and bartonella clarridgeiae infection in domestic cats from the philippines. | one hundred seven domestic cats from the philippines were serologically tested to establish the prevalence of bartonella infection. a subset of 31 of these cats also had whole blood collected to tentatively isolate bartonella strains. bartonella henselae and b. clarridgeiae were isolated from 19 (61%) of these cats. bartonella henselae type i was isolated from 17 (89%) of the 19 culture-positive cats. six cats (31%) were infected with b. clarridgeiae, of which four were coinfected with b. hensel ... | 1999 | 10348234 |
| rats of the genus rattus are reservoir hosts for pathogenic bartonella species: an old world origin for a new world disease? | bartonella species were isolated from the blood of 63 of 325 rattus norvegicus and 11 of 92 rattus rattus from 13 sites in the united states and portugal. infection in both rattus species ranged from 0% (e.g., 0/87) to approximately 60% (e.g., 35/62). a 337-bp fragment of the citrate synthase (glta) gene amplified by polymerase chain reaction was sequenced from all 74 isolates. isolates from r. norvegicus were most similar to bartonella elizabethae, isolated previously from a patient with endoca ... | 1999 | 10353885 |
| a case of cat scratch disease masquerading as lymphogranuloma venereum. | | 1999 | 10361925 |
| infected dog and cat bites. | | 1999 | 10366326 |
| conservative management of documented neuroretinitis in cat scratch disease associated with bartonella henselae infection. | bartonella henselae has been identified as the causative agent of the neuroretinitis associated with cat scratch disease (csd). immunofluorescent antibody tests with good sensitivity and specificity are available to aid in diagnosis. despite diagnostic advances, optimal management remains controversial. we present a case of documented b. henselae macular neuroretinitis managed without antibiotics and discuss antibiotic use in this condition. | 1999 | 10379716 |
| recurrent encephalopathy in cat-scratch disease. | | 1999 | 10391197 |
| presumed ocular bartonellosis. | the spectrum of diseases caused by bartonella henselae continues to expand and ocular involvement during this infection is being diagnosed with increasing frequency. | 1999 | 10365031 |
| the mutt motif family of nucleotide phosphohydrolases in man and human pathogens (review). | human cells express at least eight members of the mutt motif protein (or nudix hydrolase) family. these enzymes are believed to eliminate toxic nucleotide derivatives from the cell and regulate the levels of important signalling nucleotides and their metabolites. six have been fully or partially characterized: i) hmth1 is a nucleoside triphosphatase which restricts at-->cg transversions by specifically degrading the oxidized nucleotide 8-oxo-dgtp; ii) hapah1 preferentially degrades the signallin ... | 1999 | 10373642 |
| diagnosis of rickettsial diseases using samples dried on blotting paper. | the use of filter paper is an inexpensive and convenient method for collecting, storing, and transporting blood samples for serological studies. in addition, samples occupy little space and can be readily transported without refrigeration. rickettsial diseases often evolve according to an epidemic mode and are now considered reemerging diseases, especially in developing countries, under conditions where fieldwork could be difficult. the suitability of collecting whole-blood specimens on filter p ... | 1999 | 10391847 |
| identification of bartonella-specific immunodominant antigens recognized by the feline humoral immune system. | the seroreactivities of both naturally and experimentally infected cats to bartonella henselae was examined. serum samples collected weekly from nine cats experimentally infected with b. henselae lsu16 were tested by enzyme-linked immunosorbent assay (elisa) and western blot analysis. the magnitude and isotype of the antibody response were investigated by elisa. western blot analysis allowed the identification of at least 24 bartonella-specific antigens recognized by the cats during infection. a ... | 1999 | 10391863 |
| systemic bartonella henselae infection with hepatosplenic involvement. | systemic manifestations of bartonella henselae infection are rare in the immunocompetent host. the infection generally has initial symptoms of prolonged fever and multiple granulomatous lesions in liver and spleen. | 1999 | 10400104 |
| radiological case of the month. atypical cat-scratch disease. | | 1999 | 10401812 |
| use of polymerase chain reaction for citrate synthase gene to diagnose bartonella quintana endocarditis. | we describe aortic valve endocarditis caused by bartonella quintana in a 31-year-old man. the diagnosis was made on the basis of polymerase chain reaction amplification of the b quintana citrate synthase gene from cardiac valve tissue, the compatibility of histochemical stains of cardiac valve tissue, and serologic studies. | 1999 | 10396283 |
| [infection and angiomatous cutaneous lesions]. | the occurrence of angiomatous cutaneous lesions in the presence of an infective process is not a frequent phenomenon. most infectious diseases are associated with an exanthematous reaction. the combination of an infective illness and angiomatous lesions is seen essentially in the bartonelloses and in kaposi's disease. bartonelloses: group of infections due to alpha-proteobacteria such as bartonella. bartonella bacilliformis (bb), is the causal agent of carrion's disease, the chronic cutaneous fo ... | 1999 | 10399647 |
| isolation of a new subspecies, bartonella vinsonii subsp. arupensis, from a cattle rancher: identity with isolates found in conjunction with borrelia burgdorferi and babesia microti among naturally infected mice. | bacteremia with fever due to a novel subspecies of bartonella vinsonii was found in a cattle rancher. the subspecies shared major characteristics of the genus bartonella in terms of most biochemical features and cellular fatty acid profile, but it was distinguishable from other subspecies of b. vinsonii by good growth on heart infusion agar supplemented with x factor and by its pattern of enzymatic hydrolysis of peptide substrates. dna relatedness studies verified that the isolate belonged to th ... | 1999 | 10405408 |
| in vitro susceptibilities of four bartonella bacilliformis strains to 30 antibiotic compounds. | we have evaluated for the first time in vitro antibiotic susceptibilities of four human strains of bartonella bacilliformis, the agent of carrion's disease. our results show that b. bacilliformis, like other bartonella species, is highly susceptible to antibiotics, including most beta-lactams, aminoglycosides, chloramphenicol, rifampin, macrolides, tetracyclines, cotrimoxazole, and fluoroquinolones. | 1999 | 10428946 |
| atypical mass lesion associated with cat-scratch disease. | | 1999 | 10433602 |
| coinfection with multiple tick-borne pathogens in a walker hound kennel in north carolina. | both dogs and humans can be coinfected with various ehrlichia, bartonella, rickettsia, and babesia species. we investigated a kennel of sick walker hounds and their owners in southeastern north carolina for evidence of tick-borne infections and associated risk factors. a high degree of coinfection was documented in the dog population. of the 27 dogs, 26 were seroreactive to an ehrlichia sp., 16 to babesia canis, and 25 to bartonella vinsonii, and 22 seroconverted to rickettsia rickettsii antigen ... | 1999 | 10405413 |
| evaluation of intraspecies genetic variation within the 60 kda heat-shock protein gene (groel) of bartonella species. | a phylogenetic investigation was done on the members of the genus bartonella, based on the dna sequence analysis of the groel gene, which encodes the 60 kda heat-shock protein groel. nucleotide sequence data were determined for a near full-length fragment (1368 bp) of the groel gene of the established bartonella species and used to infer intraspecies phylogenetic relationships. phylogenetic trees were inferred from multiple sequence alignments by using both distance and parsimony methods, which ... | 1999 | 10425758 |
| development of a system for genetic manipulation of bartonella bacilliformis. | lack of a system for site-specific genetic manipulation has severely hindered studies on the molecular biology of all bartonella species. we report the first site-specific mutagenesis and complementation for a bartonella species. a highly transformable strain of b. bacilliformis, termed jb584, was isolated and found to exhibit a significant increase in transformation efficiency with the broad-host-range plasmid pbbr1mcs-2, relative to wild-type strains. restriction analyses of genomic preparatio ... | 1999 | 10427032 |
| cat scratch disease: posterior segment manifestations. | to evaluate the posterior segment findings seen in ocular cat scratch disease. | 1999 | 10442903 |
| bartonella as emerging pathogens. | | 1999 | 10447359 |
| an ulcerated nodule associated with lymphadenopathy. | | 1999 | 10456353 |
| bilateral bartonella-associated neuroretinitis. | | 1999 | 10458308 |
| characterization of bartonella henselae-specific immunity in balb/c mice. | balb/c mice were inoculated with bartonella henselae by both systemic and mucosal routes. culture analysis of tissues from mice infected intraperitoneally with a high dose of b. henselae yielded positive results 24 hr after infection. however, culture analysis of blood taken between 6 hr and 7 days after infection from groups receiving live b. henselae were negative. following intraperitoneal infection, b. henselae was detected by polymerase chain reaction in liver and mesenteric lymph nodes by ... | 1999 | 10447753 |
| bartonella henselae associated with parinaud's oculoglandular syndrome. | bartonella henselae was recovered from the conjunctival scraping of a 38-year-old woman who presented with a 2-week history of tender preauricular lymphadenopathy and a 1-day history of a red left eye. dry adherent colonies were observed on agar plates at 21 days of incubation, and the isolate was identified through conventional and molecular tests. polymerase chain reaction (pcr) amplification of a specific region of the 16s rrna gene and confirmation by a separate pcr reaction with hybridizati ... | 1999 | 10452652 |
| cat scratch encephalopathy. | cat scratch disease is usually a self-limited illness associated with tender lymph nodes, fever, malaise, and fatigue. lymphadenopathy usually resolves spontaneously within three to four months. cat scratch disease can be atypical as indicated by the presentation of our patient. | 1999 | 10461442 |
| an outbreak of acute bartonellosis (oroya fever) in the urubamba region of peru, 1998. | during may 1998, we conducted a case-control study of 357 participants from 60 households during an outbreak of acute bartonellosis in the urubamba valley, peru, a region not previously considered endemic for this disease. blood and insect specimens were collected and environmental assessments were done. case-patients (n = 22) were defined by fever, anemia, and intra-erythrocytic coccobacilli seen in thin smears. most case-patients were children (median age = 6.5 years). case-patients more frequ ... | 1999 | 10463692 |
| microbes and sequestered substances as mechanisms for disease: bartonella and l-forms as common global etiological agents. | the pathogenicity of microbes may be determined by substances sequestered from blood and bound to their constituent lipid. the brain may not perceive substances sequestered by microbes, to interfere with control to maintain normal levels. pathological conditions can be induced as organisms exposed to antimicrobial substances/conditions and/or deprived of nutrients essential to cell wall synthesis, disintegrate to free lipid-bound compounds and produce l-forms that can deplete nutrients as they r ... | 1999 | 10465665 |
| seroprevalence of bartonella henselae in cats in germany. | bartonella henselae and b. quintana infections in man are associated with various clinical manifestations including cat-scratch disease, bacillary angiomatosis and bacteraemia. while cats are the natural reservoir for b. henselae, the source of b. quintana is unclear. in this study, the sera of 713 cats from germany were examined for the presence of antibodies against b. henselae, b. quintana or afipia felis by an indirect immunofluorescence assay (ifa). bartonella-specific antibody titres of > ... | 1999 | 10482296 |
| survey of three bacterial louse-associated diseases among rural andean communities in peru: prevalence of epidemic typhus, trench fever, and relapsing fever. | typhus and other louse-transmitted bacterial infections in peruvian sierra communities are known to occur but have not recently been assessed. in this study, 194 of 1,280 inhabitants of four villages in calca province in the urubamba valley were included. thirty-nine (20%) of the 194 volunteers had antibodies to rickettsia prowazekii, whereas 24 (12%) had antibodies to bartonella quintana and 2 against borrelia recurrentis. there was a significant correlation between the presence of infesting ec ... | 1999 | 10476755 |
| absence of kaposi's sarcoma-associated herpesvirus dna in bacillary angiomatosis-peliosis lesions. | bartonella henselae and b. quintana induce an unusual vascular proliferative tissue response known as bacillary angiomatosis (ba) and bacillary peliosis (bp) in some human hosts. the mechanisms of bartonella-associated vascular proliferation remain unclear. although host factors probably play a role, microbial coinfection has not been ruled out. because of the vascular proliferative characteristics noted in both kaposi's sarcoma (ks) and ba and occasional colocalization of ks and ba, the possibi ... | 1999 | 10479179 |
| shared vector-borne zoonoses of the old world and new world: home grown or translocated? | humans inhabiting the old world and new world share a wide variety of pathogens. processes that result in the disjunct biogeographic distribution of pathogens with common vertebrate reservoirs or vectors are more difficult to unravel than those influencing the distribution of infections spread only through human-to-human transmission. the origins of species and complexes of tick-borne bacteria are unclear. the agent of lyme borreliosis may have speciated in the new world following geographical i ... | 1999 | 10476548 |
| cat-scratch neuroretinitis. | cat-scratch disease is a subacute regional lymphadenitis, usually preceded by a history of a cat scratch or exposure to kittens. the disease is caused by bartonella henselae, and possibly bartonella quintana, pleomorphic gram-negative rods formerly known as rochalimaea henselae and rochalimaea quintana. ocular involvement is rare and typically manifests as either parinaud's oculoglandular syndrome or neuroretinitis. patients with neuroretinitis resulting from cat-scratch disease may be asymptoma ... | 1999 | 10506816 |
| semiquantitative species-specific detection of bartonella henselae and bartonella quintana by pcr-enzyme immunoassay. | bartonella henselae is the main causative agent of cat-scratch disease, and both b. henselae and bartonella quintana cause angioproliferative disorders such as bacillary angiomatosis. to increase the sensitivity of bartonella detection by pcr and to improve the species differentiation, we developed a semiquantitative, species-specific pcr-based enzyme immunoassay (eia). the 16s rrna gene was selected as the target sequence. internal nucleotide sequences derived from the amplified 16s rrna region ... | 1999 | 10488160 |
| molecular analysis of riboflavin synthesis genes in bartonella henselae and use of the ribc gene for differentiation of bartonella species by pcr. | the biosynthesis pathway for riboflavin (vitamin b(2)), the precursor of the essential cofactors flavin mononucleotide and flavin adenine dinucleotide, is present in bacteria and plants but is absent in vertebrates. due to their conservation in bacterial species and their absence in humans, the riboflavin synthesis genes should be well suited either for detection of bacterial dna in human specimens or for the differentiation of pathogenic bacteria by molecular techniques. a dna fragment carrying ... | 1999 | 10488170 |
| prevalence of antibodies to bartonella henselae in patients with suspected cat scratch disease (csd) in italy. | cat scratch disease (csd) is a relatively new diagnosed illness with clinical signs of self-limiting regional lymphadenopathy accompanied by symptoms of fever and malaise, to encephalopathy and neuropathy, occurring after a cat scratch or flea bite. bartonella henselae is now accepted as the etiologic agent of csd. from january 1994 to september 1998, 412 patients were evaluated for suspect csd in italy. sera were tested for antibodies to b. henselae by a commercially available indirect immunofl ... | 1999 | 10485354 |
| seroepidemiology of bartonella vinsonii subsp. berkhoffii infection in california coyotes, 1994-1998. | the prevalence of antibodies to bartonella vinsonii subsp. berkhoffii in coyotes (canis latrans) in california ranged from 51% in central to 34% in southern and 7% in northern california. seropositive coyotes were more likely to be from coastal than inland counties (p clustered distribution of bartonella seropositivity in coyotes suggests that b. vinsonii subsp. berkhoffii infection is vectorborne. further investigation is warranted to evaluate which arthropods are vectors and what the mode of t ... | 1999 | 10511529 |
| bartonella vinsonii subsp. berkhoffii and related members of the alpha subdivision of the proteobacteria in dogs with cardiac arrhythmias, endocarditis, or myocarditis. | cardiac arrhythmias, endocarditis, or myocarditis was identified in 12 dogs, of which 11 were seroreactive to bartonella vinsonii subspecies berkhoffii antigens. historical abnormalities were highly variable but frequently included substantial weight loss, syncope, collapse, or sudden death. fever was an infrequently detected abnormality. cardiac disease was diagnosed following an illness of short duration in most dogs, but a protracted illness of at least 6 months' duration was reported for fou ... | 1999 | 10523564 |
| [two cases of suspected bartonella henselae infection from a dog]. | a 55-year-old male was admitted to our hospital because of fever and left submaxillary, right axillary, and left inguinal lymphadenopathy. a presumptive diagnosis of rickettsiosis was made and treatment with oral doxycycline was started. lymphadenopathy was partialy resolved after antibiotics treatment. ablation of the left inguinal node was done and histopathological examination showed non-hodgkin's lymphoma. lymphadenopathy was resolved by chemotherapy. the second patient, a 40-year-old male, ... | 1999 | 10535269 |
| changing epidemiology of infections in patients with neutropenia and cancer: emphasis on gram-positive and resistant bacteria. | over the past 3 decades, considerable changes have occurred in the types of bacteria causing infection in febrile patients with neutropenia and cancer. twenty years ago, gram-negative bacteria caused approximately 70% of bloodstream infections. as a probable consequence of long-dwelling intravascular devices, fluoroquinolone prophylaxis, and high-dose chemotherapy-induced mucositis, there has been a shift toward gram-positive coccal bacteremia. in most centers today, approximately 70% of bactere ... | 1999 | 10530434 |
| 1st international conference on bartonella as emerging pathogens. tubingen, germany, march 5-7, 1999. abstracts. | | 1999 | 10532824 |
| unusual eruption as a presenting symptom of cat scratch disease. | cat scratch disease (csd) is a common infectious cause of subacute regional lymphadenopathy. bartonella henselae is the principal etiologic agent. about 10% of csd patients experience atypical manifestations, including rashes. the most common cutaneous manifestation of csd is a papule at the inoculation site. we report a case of csd presenting with an eruption on the upper trunk, reminiscent of sweet's syndrome, accompanied by lymphadenopathy, arthralgia, and fever. response to systemic corticos ... | 1999 | 10534662 |
| ocular manifestations of cat-scratch disease. | bartonella henselae has only recently been isolated, characterized, and found to be the principal cause of cat-scratch disease (csd). the availability of specific serologic investigations has allowed the recognition of a spectrum of ocular csd syndromes that previously were ill defined and considered idiopathic. the primary inoculation complex causing regional lymphadenopathy is represented in the eye by parinaud's oculoglandular syndrome; b. henselae is the most common cause. leber's neuroretin ... | 1999 | 10537781 |
| serological evidence of bartonella spp. infection in the uk. | we reviewed serological and epidemiological data relating to 1000 consecutive patients from whom specimens were submitted for estimation of bartonella antibodies, using mrl diagnostics bartonella ifa igm and igg kits. using 289 control sera, we estimated the specificity of the kits as > or = 99.0%. evidence of bartonella infection was found in 16.3% of patients examined. rates varied by patient group: 20% of patients for whom a diagnosis of cat scratch disease (csd) was considered probable had e ... | 1999 | 10579442 |
| demonstration of bartonella grahamii dna in ocular fluids of a patient with neuroretinitis. | we describe the clinical and laboratory features of a 55-year-old human immunodeficiency virus-negative female patient who presented with bilateral intraocular inflammatory disease (neuroretinitis type) and behavioral changes caused by a bartonella grahamii infection. diagnosis was based on the pcr analysis of dna extracted from the intraocular fluids. dna analysis of the pcr product revealed a 100% identity with the 16s rrna gene sequence of b. grahamii. the patient was successfully treated wit ... | 1999 | 10565926 |
| identification of bartonella species directly in clinical specimens by pcr-restriction fragment length polymorphism analysis of a 16s rrna gene fragment. | it is now established that two species of bartonella, namely, bartonella henselae and b. quintana, cause bacillary angiomatosis in human immunodeficiency virus-infected patients. in addition, b. henselae causes cat scratch disease and b. quintana, b. henselae, and b. elizabethae can cause bacteremia and endocarditis in immunocompetent persons. we have developed a pcr-restriction fragment length polymorphism-based assay for direct detection and identification to species level of bartonella in cli ... | 1999 | 10565929 |
| [hepatic and splenic micro-abscess in cat scratch disease. report of a case]. | cat-scratch disease (csd) is an infection caused by a gram-negative bacillus known as bartonella henselae. hepatosplenic disease occurs in only 0.3-0.7% of patients. in this report we describe a 7-year-old male presented with a 4-week history of fever, after diagnosis of csd with regional lymphoadenitis. ultrasonography and tomography identified hepatic and splenic abscesses. antibiotic treatment for three months was associated with resolution of lesions. in patients affected by csd, ultrasonogr ... | 1999 | 10570789 |
| a case of cat scratch disease masquerading as lymphogranuloma venereum. | | 1999 | 10582643 |
| diagnostic and therapeutic challenges. | | 1999 | 10606459 |
| immune response of neonatal specific pathogen-free cats to experimental infection with bartonella henselae. | the purpose of this study was to determine whether neonatal cats develop and maintain a persistent bacteremia for longer than do adult cats with a normal mature immune system, and whether neonatal cats are susceptible to infection with bartonella henselae by oral inoculation. neonatal specific pathogen-free (spf) cats were inoculated with b. henselae intradermally (n = 4) or orally (n = 5) or with 0.9% nacl (n = 2). blood was collected periodically through 16 weeks post-inoculation (pi) for sero ... | 1999 | 10587303 |
| live bartonella henselae enhances endothelial cell proliferation without direct contact. | the proliferation of human umbilical vein endothelial cells (huvecs) cocultivated with live b. henselae was enhanced in a bacterial dose-dependent manner, and the stimulatory effect was specific to vascular endothelial cells. the inactivation of b. henselae by uv or heat treatment abolished its stimulatory activity, suggesting that live bacteria is necessary for the growth stimulation effect. to investigate the role of direct contact, live b. henselae were separated from huvecs by a filter membr ... | 1999 | 10588914 |
| contact-dependent hemolytic activity distinct from deforming activity of bartonella bacilliformis. | although bartonella bacilliformis causes a severe anemia in humans, this study presents the first report of hemolytic activity by b. bacilliformis. the activity was not apparent in culture supernatants but was reliably detected when b. bacilliformis cells were centrifuged onto erythrocytes prior to incubation. abrogation of hemolytic activity by proteinase k treatment suggested the hemolysin was a bartonella protein. even though hemolysis required relatively long incubation times, de novo protei ... | 2000 | 10612742 |
| sonicated diagnostic immunoblot for bartonellosis. | two simple bartonella bacilliformis immunoblot preparation methods were developed. antigen was prepared by two different methods: sonication of whole organisms or glycine extraction. both methods were then tested for sensitivity and specificity. well-defined control sera were utilized in the development of these diagnostic immunoblots, and possible cross-reactions were thoroughly examined. sera investigated for cross-reaction with these diagnostic antigens were drawn from patients with brucellos ... | 2000 | 10618267 |
| species-specific monoclonal antibodies for rapid identification of bartonella quintana. | seven species-specific monoclonal antibodies (mabs) to bartonella quintana were produced and characterized. the mabs were of the immunoglobulin g class and reacted only with 13 b. quintana strains in indirect microimmunofluorescence and western immunoblotting assays. they did not react with eight other bartonella spp., including bartonella henselae, the most closely related species, and a selected mab did also not react with nine other strains of gram-negative bacteria. the mabs reacted mainly w ... | 2000 | 10618271 |
| bartonella infection: a significant cause of native valve endocarditis necessitating surgical management. | | 2000 | 10612779 |
| the body louse as a vector of reemerging human diseases. | the body louse, pediculus humanus humanus, is a strict human parasite, living and multiplying in clothing. louse infestation is associated with cold weather and a lack of hygiene. three pathogenic bacteria are transmitted by the body louse. borrelia recurrentis is a spirochete, the agent of relapsing fever, recently cultured on axenic medium. historically, massive outbreaks have occurred in eurasia and africa, but currently the disease is found only in ethiopia and neighboring countries. bartone ... | 1999 | 10589908 |
| [seroepidemiology of bartonella henselae infection in hiv-infected patients]. | bartonella henselae infections are closely related to numerous clinical infections of growing interest in spain. since immunosuppressed patients are a potential risk group for infection by this bacteria, the aim of the present was to study the seroepidemiology of b. henselae infection in a risk group (patients with hiv infection) and in a control group (donors). | 1999 | 10614075 |
| detection of selected fastidious bacteria. | the intent of this article is to describe the optimal methods for culture recovery of 7 fastidious bacteria: legionella species, brucella species, francisella tularensis, leptospira species, borrelia burgdorferi, bartonella species, and bordetella species. these organisms share much in common beyond the fact that their genus names all end in the letter "a." culture recovery of these organisms, even from adequate clinical specimens, is logistically demanding, often costly, and lacking in both tim ... | 2000 | 10619747 |
| seroprevalence of bartonella henselae among hiv-1 infected patients in japan. | | 1999 | 10655688 |
| [cat scratch disease]. | | 1999 | 10635816 |
| sequence variation in the ftsz gene of bartonella henselae isolates and clinical samples. | in a search for methods for subtyping of bartonella henselae in clinical samples, we amplified and sequenced a 701-bp region in the 3' end of the ftsz gene in 15 b. henselae isolates derived from cats and humans in the united states and europe. the ftsz sequence variants that were discovered were designated variants bh ftsz 1, 2, and 3 and were compared with 16s rrna genotypes i and ii of the same isolates. there was no ftsz gene variation in the strains of 16s rrna type i, all of which were bh ... | 2000 | 10655367 |
| bacillary angiomatosis by bartonella quintana in an hiv-infected patient. | bacillary angiomatosis and bacillary peliosis are opportunistic infections caused by bartonella henselae and bartonella quintana, which occur in patients with late-stage infection. we report a case of bacillary angiomatosis in an hiv-infected patient with skin, bone, and probably liver involvement, the identification of the agent (b quintana ) was done by polymerase chain reaction in the skin specimen. the patient had complete regression of all lesions after a 6-month regimen of oral erythromyci ... | 2000 | 10642694 |
| granulomatous disease associated with bartonella infection in 2 dogs. | shortly after removal of an engorged tick from the left ear, a 4-year-old greyhound was referred for evaluation of fever and a rapidly enlarging mass in the region of the left submandibular lymph node. histopathologic evaluation of the lymph node resulted in a diagnosis of severe granulomatous lymphadenitis. an 11-year-old mixed-breed dog was referred for evaluation of a 6-week history of serous nasal discharge. histologic examination of a surgical biopsy from a nasal mass indicated multifocal g ... | 2000 | 10668815 |
| conservation of the 17-kilodalton antigen gene within the genus bartonella. | the 17-kda antigen of bartonella henselae has previously been shown to elicit a strong humoral immune response in patients with cat scratch disease (csd) and to be useful in screening human serum samples for csd. in this study, pcr amplification of genes homologous to the 17-kda antigen gene of b. henselae was performed using genomic dnas from several species of bartonella, including the currently recognized human pathogens. amplicons of similar size were demonstrated using the following chromos ... | 2000 | 10702501 |
| in vitro susceptibilities of rickettsia and bartonella spp. to 14-hydroxy-clarithromycin as determined by immunofluorescent antibody analysis of infected vero cell monolayers. | the in vitro susceptibilities of rickettsia akari, rickettsia conorii, rickettsia prowazekii, rickettsia rickettsii, bartonella elizabethae, bartonella henselae and bartonella quintana to different concentrations of clarithromycin, 14-hydroxy-clarithromycin (the primary metabolite of clarithromycin) and tetracycline in vero cell cultures, were determined by enumeration of immunofluorescently-stained bacilli. the extent of antibiotic-induced inhibition of foci was recorded for each dilution of an ... | 2000 | 10702548 |
| are bartonella emerging and re-emerging pathogens in southern africa? | | 2000 | 10721382 |
| parapharyngeal abscess due to cat-scratch disease. | the spectrum of illness attributed to cat-scratch disease (csd) continues to expand. although a common cause of cervical adenitis in children, csd has not been associated as a cause of deep fascial space infections of the head and neck. we describe a child with extensive parapharyngeal adenitis and abscesses due to csd confirmed by histological and serological evaluations. | 2000 | 10722453 |
| prevalence of bartonella henselae antibody in florida panthers. | serum samples from 28 free-ranging florida panthers (puma concolor coryi) and seven mountain lions from texas (p. concolor stanleyana) living in south florida (usa) between 1997 to 1998 were tested for antibodies to bartonella henselae. twenty percent (7/35) of the samples were reactive to b. henselae antisera with a subspecies prevalence of 18% (5/ 28) for florida panthers and 28% (2/7) for cougars from texas (usa). there was not a significant sex related difference in infection rates among the ... | 2000 | 10682759 |
| peliosis hepatis in a dog infected with bartonella henselae. | a 6-year-old spayed female golden retriever was examined because of generalized weakness and abdominal distention. abdominal ultrasonography revealed a large quantity of peritoneal fluid. in addition, the liver appeared larger than normal and contained multiple, small, nodular masses and cyst-like structures. abdominal exploratory surgery was performed, and 5 l of serosanguineous peritoneal fluid was removed. gross lesions were not found in the stomach, kidneys, intestines, adrenal glands, or ur ... | 2000 | 10687006 |
| metal requirements of a diadenosine pyrophosphatase from bartonella bacilliformis: magnetic resonance and kinetic studies of the role of mn2+. | recombinant iala protein from bartonella bacilliformis is a monomeric adenosine 5'-tetraphospho-5'-adenosine (ap4a) pyrophosphatase of 170 amino acids that catalyzes the hydrolysis of ap4a, ap5a, and ap6a by attack at the delta-phosphorus, with the departure of atp as the leaving group [cartwright et al. (1999) biochem. biophys. res. commun. 256, 474-479]. when various divalent cations were tested over a 300-fold concentration range, mg2+, mn2+, and zn2+ ions were found to activate the enzyme, w ... | 2000 | 10694402 |
| bartonella vinsonii subsp. berkhoffii as an agent of afebrile blood culture-negative endocarditis in a human. | we report a case of endocarditis in a human infected with bartonella vinsonii subsp. berkhoffii, which causes bacteremia and endocarditis in dogs. bacterial identification was established by pcr amplification and sequencing of an intergenic spacer region (its1), 16s ribosomal dna, and a gene encoding citrate synthase (glta). bartonella antibodies were detected by immunofluorescence. | 2000 | 10747175 |
| patterns of infection of haemoparasites in the fat sand rat, psammomys obesus, in tunisia, and effect on the host. | two bacterial and one protozoan blood parasite, belonging to the genera bartonella, borrelia and babesia, were studied in a tunisian population of psammomys obesus. seasonal changes in the abundance of the parasites and host were monitored in a longitudinal field survey lasting 17 months. blood samples collected during eight rodent-trapping sessions, between september 1995 and january 1997, were examined microscopically. bartonella sp. showed a seasonal pattern, with most transmission occurring ... | 2000 | 10723524 |
| a bacteriophage-like particle from bartonella bacilliformis. | bartonella bacilliformis and bartonella henselae, the respective agents of oroya fever and cat-scratch disease in humans, are known to produce bacteriophage-like particles (blps) that package 14 kbp segments of the host chromosome. data from this study suggest that other bartonella species including bartonella quintana, bartonella doshiae and bartonella grahamii also contain similar blps, as evidenced by the presence of a 14 kbp extrachromosomal dna element in their genomes, whereas bartonella e ... | 2000 | 10746763 |
| cloning, sequencing, and expression of three bartonella henselae genes homologous to the agrobacterium tumefaciens virb region. | a 17-kda, immunodominant antigen of bartonella henselae houston-1 has previously been cloned, sequenced, and characterized. this clone (h13) contains the 17-kda antigen gene plus a partial open reading frame, designated orf1, which is 459 nucleotides long and is directly upstream of the 17-kda gene. comparison of the deduced partial amino acid sequence of orf1 with that of other known genes in genbank revealed significant identity with several other bacterial virulence genes, including virb4 of ... | 2000 | 10749166 |
| bartonellosis. new and old. | the number of species that comprise the family of bartonellaceae, genus bartonella, has recently increased from one to 11 species, five of which have been associated with different diseases and syndromes in humans. the rapidly growing number of human pathogens has led several investigators to regard bartonellosis and other associated syndromes as important emerging infectious diseases. this article presents the history and epidemiology, clinical features, diagnosis, and treatment of bartonellosi ... | 2000 | 10738670 |
| in vitro activities of telithromycin (hmr 3647) against rickettsia rickettsii, rickettsia conorii, rickettsia africae, rickettsia typhi, rickettsia prowazekii, coxiella burnetii, bartonella henselae, bartonella quintana, bartonella bacilliformis, and ehrlichia chaffeensis. | in vitro activities of telithromycin compared to those of erythromycin against rickettsia spp., bartonella spp., coxiella burnetii, and ehrlichia chaffeensis were determined. telithromycin was more active than erythromycin against rickettsia, bartonella, and coxiella burnetii, with mics of 0.5 microg/ml, 0.003 to 0.015 microg/ml, and 1 microg/ml, respectively, but was inactive against ehrlichia chaffeensis. | 2000 | 10770788 |
| hhv-8 (kshv) is not associated with bacillary angiomatosis. | bacillary angiomatosis is a rare pseudoneoplastic angioproliferative lesion occurring in patients with aids. this condition has been associated with bartonella henselae and bartonella quintana infections. human herpesvirus 8 (hhv-8) is thought to be the causative agent of kaposi's sarcoma, a vasoproliferative neoplasm, also commonly found in patients with aids. the presence of hhv-8 in a cohort of patients with bacillary angiomatosis was investigated. | 1999 | 10748868 |
| prevalence of bartonella henselae, bartonella clarridgeiae and the 16s rrna gene types of bartonella henselae among pet cats in japan. | the authors investigated bacteriologically the prevalence of bartonella infection among 690 pet cats derived from 10 private animal hospitals in six cities (sapporo, hokkaido prefecture; sendai, miyagi prefecture; joetsu, niigata prefecture; fujisawa, kanagawa prefecutre; kyoto, kyoto prefecture; sanda, hyogo prefecutre) and 4 counties (mishima, osaka prefecture; hikawa, shimane prefecture; aira, kagoshima prefecture; shimajiri, okinawa prefecture) located from the north to the south of japan. b ... | 2000 | 10770599 |