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leber's neuroretinitis in a patient with serologic evidence of bartonella elizabethae. 19989654422
prospective randomized double blind placebo-controlled evaluation of azithromycin for treatment of cat-scratch disease.to determine the efficacy of azithromycin in the treatment of patients with typical cat-scratch disease.19989655532
[infective endocarditis caused by unusual microorganisms].all series of infective endocarditis had a variable proportion of cases without an etiologic agent because all cultures were negative. new microbiologic techniques have permitted the discovery of the role of many microorganisms in infective endocarditis. c. burnetii is an increasing causative agent of subacute infective endocarditis. in the diagnosis, to the detection of antiphase-i antibodies, immunohistochemical, molecular techniques and cellular cultures have been added. total cure is difficu ...19989658953
[liver changes in aids. retrospective analysis of 227 autopsies of hiv-positive patients].in a retrospective study of a 12-year period (1981-1992) liver histology was analyzed in 227 autopsied patients infected with the human immunodeficiency virus. normal histology could only be documented in 29 patients (13%). in the majority of cases (56%) uncharacteristic changes were seen such as steatosis (34%), hemosiderosis (10%) or non-specific reactive hepatitis (7%). the finding of hepatic peliosis obtained in 4 patients was not associated with inflammatory liver changes, especially infect ...19989648144
seroprevalence of antibodies to bartonella henselae in patients with cat scratch disease and in healthy controls: evaluation and comparison of two commercial serological tests.serologic testing for the presence of antibodies to bartonella henselae is a widely accepted diagnostic procedure for laboratory confirmation of the diagnosis of cat scratch disease (csd). in this study a commercially available indirect immunofluorescence assay (ifa) based on b. henselae-infected human larynx carcinoma cells (test a) was evaluated. sera from 42 patients with csd (20 confirmed by pcr) and 270 sera from healthy controls (consisting of 63 cat owners, 65 individuals whose last close ...19989665953
constitutive and inducible green fluorescent protein expression in bartonella henselae.the green fluorescent protein (gfp) gene was expressed on a plasmid in b. henselae, and gfp-expressing bacteria were visualized by fluorescence microscopy. hep-2 cells infected with gfp-expressing bacteria were separated from uninfected cells with a fluorescence activated cell sorter. promoter fusions of b. henselae chromosomal dna to gfp were examined by flow cytometry, and a b. henselae groel promoter fusion which induced expression at 37 degreesc was isolated.19989673287
use of retinal biopsy to diagnose bartonella (formerly rochalimaea) henselae retinitis in an hiv-infected patient.a patient with the acquired immunodeficiency syndrome developed bilateral retinitis due to a bartonella (formerly rochalimaea) henselae infection. a retinal biopsy was performed when severe and progressive retinal infection failed to respond to empirical treatment for cytomegalovirus and toxoplasma gondii. the biopsy specimen was stained with routine histopathological stains and the steiner silver stain. ribosomal dna was extracted from formalinfixed, paraffin-embedded retinal tissue and amplifi ...19989682711
von willebrand factor proteolysis and doxycycline in thrombotic thrombocytopenic purpura. 19989690440
[cat-scratch disease. presentation of 2 cases in a family with serologic follow-up and discussion of diagnostic methods].two cases are reported of cat scratch disease which we consider worth describing both because of their familial presentation (the involved patients were brothers) and the serologic follow-up performed after diagnosis, which showed significant increases in igg antibody titers to bartonella henselae in both patients, one on day 35 and the other on day 45 after diagnosis. cat scratch disease is a rarely diagnosed condition in our environment and it is easily misdiagnosed with other regional lymphad ...19989691742
images in clinical medicine. verruga peruana. 19989700179
radiological case of the month. cat-scratch disease with hepatic and splenic involvement. 19989701150
chest-wall abscess due to cat-scratch disease (csd) in an adult with antibodies to bartonella clarridgeiae: case report and review of the thoracopulmonary manifestations of csd.we describe a patient who presented with a massive chest-wall abscess after a severe debilitating illness that lasted 3 months. steroid therapy, administered for 4 weeks, masked the slow development of an extensive axillary and chest-wall abscess. after multiple negative tests, the patient's prolonged illness was diagnosed as cat-scratch disease (csd). an indirect fluorescent antibody test revealed that two convalescent serum samples were positive for igg to bartonella clarridgeiae, but no other ...19989709886
[reactive arthritis after cat bit: a rare manifestation of cat scratch disease--case report and overview].cat scratch disease (csd) is a rarely recognized infectious disease in germany. only a few years ago the causative agent, bartonella henselae, could be isolated. the typical clinical manifestations of csd consist of skin changes at the inoculation site and a benign lymphadenopathy; other manifestations are rare. we report the case of a 47 year old woman, who developed a reactive spondylarthropathy with synovitis of finger joints, polyarthralgias of large- and medium-sized joints, and inflammator ...19989702836
cat scratch disease: the rare role of afipia felis.since its isolation in 1988, afipia felis has been associated with cat scratch disease (csd) in only one report and its role in csd has been questioned. we have cultured a. felis from a lymph node of a patient with csd. 16s rrna gene sequencing, dna relatedness studies, fatty acid analysis, and pcr of the a. felis ferredoxin gene showed that the isolate is identical to the previously reported a. felis isolate. to determine the role of a. felis in csd, pcr of the 16s rrna gene followed by hybridi ...19989705382
sequential evaluation of dogs naturally infected with ehrlichia canis, ehrlichia chaffeensis, ehrlichia equi, ehrlichia ewingii, or bartonella vinsonii.historically, disease manifestations in dogs seroreactive to ehrlichia canis antigens by indirect immunofluorescent antibody testing have been attributed to infection with either e. canis or ehrlichia ewingii. a 1996 study by dawson and colleagues provided pcr evidence that healthy dogs from southeastern virginia could be naturally infected with ehrlichia chaffeensis. this observation stimulated us to determine which ehrlichia spp. infected sick dogs that were referred to our hospital from the s ...19989705408
anterior uveitis associated with cat scratch disease. 19989713073
construction of versatile high-level expression vectors for bartonella henselae and the use of green fluorescent protein as a new expression marker.expression vectors suitable for directing high levels of protein synthesis in bartonella henselae have been constructed based on the mobilisable broad-host-range (incq) plasmidpmmb206. they confer kanamycin resistance and feature the taclac (tac-lacuv5 in tandem) promoters in front of a polylinker followed by the rrnb transcriptional stop point. while expression of genes fused to the taclac promoter is constitutive in one vector, the laciq gene carried by the other vector allows a controlled, ip ...19989714815
outbreak of epidemic typhus associated with trench fever in burundi.after a 12-year absence, epidemic typhus has re-emerged among the displaced population of burundi. following the outbreak of civil war in 1993, over 760000 people now inhabit refugee camps, under appalling conditions. a typhus outbreak occurred among prisoners in a jail in n'gozi in 1995. at the time, the disease was not recognised, and was referred to as sutama. reports of sutama among the civilian population date back to late 1995 and, in association with body-louse infestation, the disease ha ...19989717922
the 'emergence' of bartonella and the development of molecular discovery methods for microbial pathogens. 19989718924
cat-scratch disease with an extraaxial mass.ct and mr imaging of the brain and gallium-67 scintigraphy showed an enhancing, gallium-avid mass in the left middle cranial fossa of a 10-year-old girl. craniotomy revealed an inflammatory mass related to the left trigeminal nerve. the lesion contained rodlike bacteria, and serologic tests were positive for cat-scratch disease. neurologic involvement in cat-scratch disease is uncommon, and the presence of organisms in neural tissue has not been reported.19989726471
bartonella henselae isolated from cats in zimbabwe. 19989734895
a farmer with a lump in his throat. 19989734943
striking a balance in maternal immune response to infection. 19989734878
postpartum coma. 19989734888
bartonella serology for patients with intraocular inflammatory disease.to determine the role of bartonella henselae in intraocular inflammatory disease and identify its clinical features.19989730179
a case of hemolytic uremic syndrome associated with epstein-barr virus infection.the precise etiology of hemolytic uremic syndrome (hus) is unknown. however, it has been associated with bacterial (shigella, salmonella, e. coli, s. pneumoniae), bartonella, and viral (coxsackie, echo, influenza, varicella. epstein-barr) infections and with endotoxemia. recently, we experienced a case of hus in a 16-year-old boy who was in the acute phase of an epstein-barr virus (ebv) infection. he had typical manifestations of hus and ebv infection. he also transiently presented disseminated ...19989735670
cat-scratch disease manifesting as unifocal helioid choroiditis. 19989747695
comparison of different dna fingerprinting techniques for molecular typing of bartonella henselae isolates.seventeen isolates of bartonella henselae from the region of freiburg, germany, obtained from blood cultures of domestic cats, were examined for their genetic heterogeneity. on the basis of different dna fingerprinting methods, including pulsed-field gel electrophoresis (pfge), enterobacterial repetitive intergenic consensus (eric)-pcr, repetitive extragenic palindromic (rep) pcr, and arbitrarily primed (ap)-pcr, three different variants were identified among the isolates (variants i to iii). va ...19989738053
cat scratch disease due to bartonella henselae serotype marseille (swiss cat) in a seronegative patient. 19989742017
cat-scratch disease caused by bartonella henselae: the first case report in taiwan.we report a typical case of cat-scratch disease caused by bartonella henselae, in taiwan. a 20-year-old man developed right axillary lymphadenopathy 2 weeks after being scratched on his right hand by a kitten. the axillary lymphadenopathy resolved gradually and spontaneously after 10 weeks without specific treatment. serologic tests were not done during the acute stage of the event. however, an immunofluorescent antibody test performed during the convalescent stage was positive for b. henselae a ...19989747069
detection of bartonella henselae by polymerase chain reaction in brain tissue of an immunocompromised patient with multiple enhancing lesions. case report and review of the literature.the authors report the first dna-based diagnosis of bartonella henselae cultured from a brain lesion in a patient with acquired immune deficiency syndrome. this human immunodeficiency virus-infected patient presented with altered mental status, fever, and diabetes insipidus. magnetic resonance imaging revealed multifocal parenchymal and leptomeningeal involvement, which was confirmed on studies of tissue biopsy samples. using the polymerase chain reaction and gene sequencing techniques, the auth ...19989761060
disseminated bartonella henselae (cat-scratch disease): appearance of multifocal osteomyelitis with mr imaging. 19989763023
identification of brucella by ribosomal-spacer-region pcr and differentiation of brucella canis from other brucella spp. pathogenic for humans by carbohydrate profiles.molecular and chemical characteristics often provide complementary information in the differentiation of closely related organisms. the genus brucella consists of a highly conserved group of organisms. identification of the four species pathogenic in humans (brucella melitensis, brucella abortus, brucella suis, and brucella canis) is problematic for many clinical laboratories that depend primarily on serology and phenotypic characteristics to differentiate species. pcr amplification of the 16s-2 ...19989774568
[down the claws!]. 19989775093
[cat scratch disease: description of a new case]. 19989763751
cat-scratch disease osteomyelitis from a dog scratch.osteomyelitis is a rare manifestation of cat-scratch disease in patients who do not have aids. the clinical presentation and non-specific subacute course of the disease make diagnosis difficult. we present a child with osteomyelitis of a metacarpal following a dog scratch. bartonella henselae was found to be the aetiological agent. the bone healed after treatment with antibiotics. increased awareness and a comprehensive medical history are needed to identify patients with suspected bartonella he ...19989768882
[fever of unknown origin]. 19989773562
experimental infection of domestic cats with bartonella henselae by inoculation of ctenocephalides felis (siphonaptera: pulicidae) feces.caged cat fleas, ctenocephalides felis (bouché), were fed on 6 cats; 3 cats were injected with 5 x 10(7) colony forming units of bartonella henselae intradermally and 3 cats were injected with an equal volume of saline. after the fleas fed for 4 d, 5 groups of 50 b. henselae-exposed fleas were caged and allowed to feed on 5 cats for 6 d. five cats each were injected intradermally with 1 ml of saline containing 45 mg of feces from b. henselae-exposed fleas. five cats were fed 50 b. henselae-expos ...19989775583
subacute orbital abscess in a four-year-old girl with a new kitten. 19989779778
[determination of anti-bartonella henselae antibody by indirect fluorescence antibody test--comparison of two types of antigen: non-cocultivated b. henselae and cocultivated b. henselae with vero cells].serum anti-bartonella henselae igg and igm antibody titers for the diagnosis of cat scratch disease (csd) were determined by indirect fluorescence antibody (ifa) tests. b. henselae as antigen were harvested either by cocultivating with vero cells (cocultivated b. henselae) or by cultivating without them (non-cocultivated b. henselae). based on the results on 110 healthy adults, cut off values were set at 1:32 for igg, and < 1:20 for igm antibodies. according to these criteria, igg antibody was p ...19989780582
[the microbiology of infectious endocarditis].if streptococci and staphylococci remain the main bacteria responsible for infective endocarditis (80%), the emergence of streptococcus bovis associated with intestinal lesions, the confirmation of the role of coxiella burnetii, and the discovery of the responsibility of bartonella sp in case of negative blood culture endocarditis have been the principal microbiological modifications during the last few years. blood cultures performed under the best technical conditions and the examination and c ...19989781112
cat-scratch encephalopathy. 19989781592
murine model of bartonella henselae infection in the immunocompetent host.bartonella henselae is an emerging pathogen causing cat scratch disease, bacillary angiomatosis, and peliosis hepatis. progress in understanding the pathogenesis of and the immune response to these infections has been limited by the lack of an animal model. following intraperitoneal infection of c57bl/6 mice with b. henselae, organs were cleared of cultivatable bacteria within 6 days. in contrast, b. henselae dna could be detected in liver tissue for at least 3 months. liver tissue showed granul ...19989784568
bacillary angiomatosis in immunocompromised patients.to report seven cases of bacillary angiomatosis; to evaluate the most useful diagnostic tools; to analyse the clinical and epidemiological features associated with bartonella quintana or bartonella henselae infections.19989792380
outer membrane proteins of bartonella henselae and their interaction with human endothelial cells.members of the genus bartonella are unique in that they are bacteria which cause proliferation of microvascular endothelial cells and neovascularization (angiogenesis). the mechanisms by which bartonella henselae causes these processes are unknown. given the importance of surface-exposed determinants in the pathogenesis of many organisms, outer membrane proteins (omps) of b. henselae were identified. enrichment of the outer membrane fraction of b. henselae by sarkosyl treatment of total membrane ...19989790875
seroprevalence of bartonella henselae and toxoplasma gondii infections among pet cats in kanagawa and saitama prefectures.seroprevalence of bartonella henselae and toxoplasma gondii was investigated among 471 pet cats obtained from seven private animal hospitals in kanagawa and saitama prefectures during the period from may 1994 to june 1995. 'furthermore, 67 randomly selected from the 471 serum samples were examined for the feline immunodeficiency virus (fiv) antibody and feline leukemia virus (felv) antigen. the antibody to b. henselae was examined by an indirect immunofluorescent antibody test. t. gondii, fiv an ...19989795899
mutations in bartonella bacilliformis gyrb confer resistance to coumermycin a1.this study describes the first isolation and characterization of spontaneous mutants conferring natural resistance to an antibiotic for any bartonella species. the bartonella bacilliformis gyrb gene, which encodes the b subunit of dna gyrase, was cloned and sequenced. the gyrb open reading frame (orf) is 2,079 bp and encodes a deduced amino acid sequence of 692 residues, corresponding to a predicted protein of approximately 77.5 kda. sequence alignment indicates that b. bacilliformis gyrb is mos ...19989797224
use of the cell division protein ftsz as a means of differentiating among bartonella species.genes coding for homologs of the highly conserved cell division protein ftsz were isolated from bartonella henselae and bartonella quintana, the causative agents of cat scratch disease and trench fever, respectively. dna fragments coding for the ftsz open reading frames (orfs) were cloned into escherichia coli following pcr amplification with primers based on the ftsz sequence of the closely related species bartonella bacilliformis. the amino acid sequences predicted from the cloned b. henselae ...19989801332
[database on nucleotide sequences used as primers of microorganisms].the data base (db) "primers of microorganisms" for the accumulation and systematization of information on oligonucleotide sequences, used as primers in polymerase chain reaction, has been created. this db includes data on primers for the laboratory diagnostics of 20 bacterial genera (aerococcus, aeromonas, bartonella, borrelia, burkholderia, chlamydia, clostridium, corynebacterium, escherichia, francisella, helicobacter, legionella, listeria, mycobacterium, mycoplasma, salmonella, shigella, stap ...19989825498
two different genotypes of bartonella henselae in children with cat-scratch disease and their pet cats.two genotypes (i and ii) of bartonella henselae are involved in cat-scratch disease (csd). lymph node biopsies were taken from 3 children suffering from csd, and blood cultures were obtained from their pet cats. cat-scratch disease was confirmed serologically, histologically and by detection of b. henselae dna in all 3 lymph nodes by pcr. bartonella henselae grew in all cats' blood cultures. the first 2 children were siblings. both children and their pet cats were infected with b. henselae genot ...19989817520
isolated right-sided bartonella quintana endocarditis in an immunocompetent adult.bartonella quintana is a recently recognized cause of culture-negative left-sided endocarditis. we report a case of isolated tricuspid endocarditis caused by b. quintana in a 65-year-old alcoholic man, who also had immune-complex glomerulonephritis. b. quintana was established as the cause of the endocarditis based on serological tests and on failure of extensive efforts to isolate an alternative organism. the patient improved gradually on antibiotic therapy and did not require surgery. to our k ...19989817529
western blotting analysis of heat shock proteins of rickettsiales and other eubacteria.heat shock proteins (hsp) of four rickettsia species, three bartonella species, two ehrlichia species, orientia tsutsugamushi and seventeen other eubacterial species were characterized by the enhanced chemiluminescence western blotting (wb) technique with antibodies raised against recombinant hsp from escherichia coli and purified groes from r. typhi. although e. coli dnak and groel have epitopes that are highly conserved among the homologous proteins found in rickettsia, ehrlichia, o. tsutsugam ...19989809424
a man with fever and lymphadenopathy.a 40-year-old man presented with a three-week history of malaise, nausea, night sweats, decreased appetite, and a 15-lb weight loss. he reported having had diarrhea, occasionally with bright red blood, for the first two weeks and a temperature as high as 39.4 degrees c for the last two weeks. he had not had cough, shortness of breath, wheezing, chest pain, arthralgias, rash, or conjunctivitis. he had not eaten raw oysters or raspberries.19989826954
characterization of human immunoglobulin (ig) isotype and igg subclass response to bartonella henselae infection.serologic parameters of cat scratch disease (csd) were evaluated by western blot analysis. sera from patients with serologically confirmed csd antigen were screened for immunoglobulin (ig) isotype-specific as well as igg subclass-specific reactivity against bartonella henselae whole-cell antigen. bartonella-negative control sera were used to determine baseline antibody activity. heterogeneous b. henselae-specific igg reactivity with numerous protein bands, ranging from >150 to <17 kda, was obser ...19989826373
bartonella tribocorum sp. nov., a new bartonella species isolated from the blood of wild rats.two bartonella strains from blood of two wild rats (rattus norvegicus) living in a rural environment were isolated. these strains were distinct from all previously known bartonella species based on phenotypic and genotypic characteristics. this new species is distinguished by its trypsin-like activity, the absence of the ability to hydrolyse proline and tributyrin, its 16s rrna and citrate synthase gene sequences and by whole-dna hybridization data. this new species, for which the name bartonell ...19989828434
[bartonella quintana endocarditis. aortic localization and mitral valve abscess].bartonella quintana is an exceptionally rare cause of endocarditis. the frequency of this condition is increasing and is probably underestimated because of the difficulty in diagnosing. the clinical context is that of socially deprived classes, the agent of transmission of the germ being body lice. the commonest valve affected is the aortic valve. this infection may also give rise to a mitral annulus abscess, as in this particular case. the diagnosis should be suspected in all cases of endocardi ...19989833092
homologous protection but lack of heterologous-protection by various species and types of bartonella in specific pathogen-free cats.cat-scratch disease (csd) is caused by bartonella henselae, and possibly by b. clarridgeiae. in immuno-compromised persons, b. henselae is one of the agents causing bacillary angiomatosis. domestic cats are the main reservoir of these bacteria, which are transmitted primarily from cat to cat by fleas. possible strategies to prevent the spread of infection among cats are to eliminate flea infestation or to prophylactically immunize cats. in order to develop an appropriate vaccine, it is important ...19989839874
[serologic diagnosis of cat-scratch disease]. 19989842534
[bartonella endocarditis on native valves. apropos of 2 cases].the authors report two cases of bartonella endocarditis in native valves. the first case was a 15 year old north african girl who lived in poor social conditions and was admitted to hospital with pyrexia and congestive heart failure. investigations revealed massive mitral regurgitation due to ruptured chordae tendinae, vegetations on the pulmonary valve with severe pulmonary hypertension due to persistent ductus arteriosus. after antibiotic therapy, the patient underwent surgery for mitral valve ...19989833093
a case of cat scratch disease diagnosed by serologic tests specific for bartonella henselae. 19989833058
bartonella henselae infection from a dog. 19989853451
therapeutic options for cat-scratch disease. 19989850000
evidence of reproductive failure and lack of perinatal transmission of bartonella henselae in experimentally infected cats.five female specific pathogen-free (spf) cats inoculated intradermally with b. henselae and bacteremic for 4 weeks, and one cat inoculated with 0.9% nacl, were bred with uninfected spf male cats. the uninfected female became pregnant with one breeding, while three infected cats became pregnant 1-12 weeks later, after repeated breedings. two infected females either did not become pregnant or maintain pregnancies despite repeated breedings. infected cats produced anti-b. henselae igm and igg antib ...19989839873
[bartonellosis: i. bartonella henselae].the recent discovery of the bacterium bartonella henselae was mainly due to the development of molecular biology techniques adapted to microbial diagnosis and to the description of new human diseases linked to aids. about 10% of pet cats and 33% of stray cats harbour that bacterium in their blood. in immunocompetent patients, that bacterium is responsible for human cat scratch disease, characterized essentially by a localized lymph nodes enlargement in the vicinity of the entry site of the bacte ...19989853027
[other infections (streptococcus pneumoniae, haemophilus influenzae, pseudomonas aeruginosa, salmonella spp., campylobacter spp., nocardia asteroides, rhodococcus equi and bartonella spp.)].people infected with human immunodeficiency virus (hiv) are at increased risk for bacterial infections due to hiv-associated immunologic defects. bacterial infections were found to be, both a predictor of progression to aids and a substantial cause of mortality in pre-aids stages. most bacterial infections are caused by streptococcus pneumoniae, haemophilus influenzae, salmonella spp. and pseudomonas aeruginosa. rhodococcus equi, nocardia spp., campylobacter spp. and bartonella spp. are less com ...19989859621
optic disk edema with a macular star.a 13-year-old boy presented with acute loss of vision in his right eye of 2 weeks' duration. he had a high fever and was ill for several days, then improved but suffered recurrent episodes of sweating and a high fever. ophthalmoscopy of the right eye showed optic disk edema, mild vitreous cells, and minimal exudates in the macula. bartonella henselae titers were positive. a diagnosis of optic disk edema with a macular star secondary to cat-scratch disease was made. the patient was treated with d ...19989862313
bartonella infections: diverse and elusive.children with young cats, hiv-infected patients with low cd4 counts, and lice-infested homeless people are among those with an increased risk. clinical presentation varies with the infecting bartonella species and the host. treatment for cat-scratch disease is supportive; macrolide therapy is an appropriate choice for other bartonella infections.19989866646
the gene, iala, associated with the invasion of human erythrocytes by bartonella bacilliformis, designates a nudix hydrolase active on dinucleoside 5'-polyphosphates.iala, one of two genes associated with the invasion of human red blood cells by bartonella bacilliformis, the causative agent of several diseases, has been cloned and expressed in escherichia coli. the protein, iala, contains an amino acid array characteristic of a family of enzymes, the nudix hydrolases, active on a variety of nucleoside diphosphate derivatives. iala has been purified, identified, and characterized as an enzyme catalyzing the hydrolysis of members of a class of signaling nucleo ...19999880487
prevalence of bartonella henselae and bartonella clarridgeiae in an urban indonesian cat population.we studied evidence of bartonella henselae and bartonella clarridgeiae infection in 54 cats living in jakarta, indonesia. by using an indirect immunofluorescence assay, we found immunoglobulin g antibody to b. henselae in 40 of 74 cats (54%). the blood of 14 feral cats was cultured on rabbit blood agar plates for 28 days. bartonella-like colonies were identified as b. henselae or b. clarridgeiae by using restriction fragment length polymorphism analysis and direct sequencing of the pcr amplicons ...19999874661
bartonella henselae-based indirect fluorescence assays are useful for diagnosis of cat scratch disease. 19989867494
detection of specific cellular immune response to bartonella henselae in a patient with cat scratch disease. 19989868676
images in clinical medicine. cat scratch disease. 19999887162
[cat-scratch disease].cat-scratch disease is a subacute, regional lymphadenitis syndrome that occurs mainly in children. the causative agent is bartonella henselae. after an incubation period ranging usually between 1 and 2 weeks, red papules develop at the site of cutaneous inoculation and persist until the development of lymphadenopathy with some malaise. cases with complications have been observed including parinaud oculoglandular syndrome, encephalopathy, a variety of exanthems and granumatous hepatitis. diagnosi ...19989887661
expression of inducible nitric oxide synthase in human granulomas and histiocytic reactions.inducible nitric oxide synthase (inos) is required in immune response against infections and is involved in granuloma formation in animals; in murine macrophages, inos is induced by lipopolysaccharide and interferon-gamma. in contrast, the role of inos in human immune response against infections is still questioned, and its expression in granulomas is poorly investigated. using western blotting and immunohistochemistry, we investigated inos expression in human lymph nodes with nonspecific reacti ...19999916929
chronic bartonella quintana bacteremia in homeless patients.infection with bartonella quintana can cause trench fever, endocarditis, bacillary angiomatosis, and peliosis. an outbreak of bacteremia due to b. quintana has been reported among homeless people in seattle, and the seroprevalence is high among homeless people in both the united states and europe. body lice are known to be the vectors of b. quintana.19999895398
vaccination of cats against emerging and reemerging zoonotic pathogens.many of the emerging infectious agents that threaten the human population are either directly zoonotic or involve animals, rather than humans, as their primary reservoir in nature. vaccination of animals may be an important consideration for control of some of these diseases, and this review has specifically focused on the concept of vaccinating cats in the prevention of infection with t. gondii, b. henselae, and h. pylori. if we return to the considerations that were presented in table iii, t. ...19999890026
intracellular pathogens and the actin cytoskeleton.many pathogens actively exploit the actin cytoskeleton during infection. this exploitation may take place during entry into mammalian cells after engagement of a receptor and/or as series of signaling events culminating in the engulfment of the microorganism. although actin rearrangements are a common feature of most internalization events (e.g. entry of listeria, salmonella, shigella, yersinia, neisseria, and bartonella), bacterial and other cellular factors involved in entry are specific to ea ...19989891781
cat-scratch disease. 19999917765
management of b. henselae neuroretinitis in cat-scratch disease. 19999917766
[seroepidemiology of bartonella henselae infection in a risk group].bartonella henselae infections are closely related to a number of clinical conditions of growing interest in our environment. as cats are the reservoir, and their bites and scratches are the main transmission mechanism, we attempted to study the seroepidemiology of the infection caused by this microorganism in a risk group of patients (cat owners) and a control group (blood donors).19989930000
blood parasites of shrews from pennsylvania.we examined 30 sorex cinereus, 5 sorex fumeus, and 21 blarina brevicauda collected from pennsylvania in 1995 for blood parasites. trypomastigotes of trypanosoma sp. were visible in 13% of the s. cinereus. ten percent of s. cinereus, 20% of s. fumeus, and 14% of b. brevicauda were infected with bartonella sp. (or spp.). in s. cinereus, we detected no concurrent trypanosoma and bartonella infections.19989920338
[bartonellosis. ii. other bartonella responsible for human diseases].in addition to bartonella henselae, five other bartonella species were involved in human pathology. as for b. henselae, ectoparasites seem to be responsible for the transmission of most or all these bacterial species. b. bacilliformis is responsible for carrion's disease that occurs in some valleys of colombia, ecuador and peru. this disease is transmitted by biting of infected sandflies. the bacterial reservoir is constituted by humans only. that disease occurs either as an acute form with seve ...19999920964
[cutaneous vasculitis disclosing cat-scratch disease].we describe a case of cat-scratch disease ingnaugurated by vascular purpura and discuss the role of the causal agent, bartonella henselae.19989922863
cat-scratch disease causing status epilepticus in children.status epilepticus from cat-scratch encephalopathy is often recalcitrant to usual therapies, causing treatment to focus on critical care management of the patient that may require aggressive interventions, such as continuous pentobarbital administration. we describe two children whose initial clinical presentation of cat-scratch disease was status epilepticus with normal cerebrospinal fluid studies. a history of cat exposure (specifically, kitten and/or fleas), regional lymphadenopathy, and a pa ...19999932833
interactions of bartonella henselae with vascular endothelial cells.the emerging human pathogen bartonella henselae has the remarkable capacity to colonise vascular tissues and to stimulate vasoproliferative tumour growth. although the molecular principle of bacterium-induced neovascularisation (angiogenesis) is still unclear, recent studies have indicated a novel mechanism of endothelial colonisation that involves the formation, engulfment and uptake of a large bacterial aggregate.199910047560
body lice as tools for diagnosis and surveillance of reemerging diseases.body lice are vectors of three bacteria which cause human disease: rickettsia prowazekii, the agent of epidemic typhus; bartonella quintana, the agent of trench fever; and borrelia recurrentis, the agent of relapsing fever. a recrudescence of body lice is being observed as the numbers of individuals living under social conditions which predispose individuals to infestation have increased. because this phenomenon may lead to the reemergence of infections transmitted by body lice, we aimed to asse ...19999986818
bartonella alsatica sp. nov., a new bartonella species isolated from the blood of wild rabbits.bartonella species are considered as emerging human pathogens, with at least six different species pathogenic or possibly pathogenic for humans. however, little is known about bartonella distribution, species polymorphism and pathogenicity in mammalian species. the objective of this work was to determine the presence, the frequency and the distribution of bartonella species in wild rabbits (oryctolagus cuniculus) caught in warrens in alsace, france. humans may come into contact with wild rabbits ...199910028274
bartonella henselae infection associated with peripapillary angioma, branch retinal artery occlusion, and severe vision loss.to report atypical clinical features of bartonella henselae neuroretinitis treated with combination antibiotics.199910030575
detection of bartonella henselae dna by two different pcr assays and determination of the genotypes of strains involved in histologically defined cat scratch disease.cat scratch disease (csd) is a common cause of subacute regional lymphadenopathy, not only in children but also in adults. serological and molecular studies demonstrated that bartonella henselae is the etiologic agent in most cases of csd. amplification of b. henselae dna in affected tissue and detection of antibodies to b. henselae are the two mainstays in the laboratory diagnosis of csd. we designed a retrospective study and investigated formalin-fixed, paraffin-embedded lymph nodes from 60 pa ...199910074515
bartonella koehlerae sp. nov., isolated from cats.two of the 25 bartonella isolates recovered during a prevalence study of bartonella henselae bacteremia in domestic cats from the greater san francisco bay region were found to differ phenotypically and genotypically from all prior b. henselae isolates. these isolates, c-29 and c-30, which were recovered from the blood of two pet cats belonging to the same household, grew on chocolate agar as pinpoint colonies following 14 days of incubation at 35 degrees c in a candle jar but failed to grow on ...199910074535
bone pain after lymphadenitis. bartonella henselae granulomatous osteitis. 199910048617
cat-scratch disease with paravertebral mass and osteomyelitis.the case of a 9-year-old girl with cat-scratch disease (csd) complicated by development of a paravertebral mass and osteomyelitis is presented. following multiple scratches and inguinal lymphadenopathy, she developed back pain, and imaging demonstrated a paravertebral mass with evidence of osteomyelitis involving vertebra t9. the diagnosis was made on the basis of detection of bartonella henselae by use of molecular techniques on an aspirate from the vertebral column and supportive serology for ...199910064243
[cat-scratch disease: series of 14 cases. the diagnostic usefulness of serology].disease by cat scratch (csd) is a syndrome characterized by regional adenopathies following cat scratch or bite. despite knowing the etiologic agent of the same, there is still controversy in the diagnosis of the syndrome in daily clinical practice.199910069107
involvement of host cell tyrosine phosphorylation in the invasion of hep-2 cells by bartonella bacilliformis.we have provided evidence that exposure of human cells to protein kinase inhibitors results in decreased invasion of these cells by bartonella bacilliformis in a dose-dependent manner. preincubation of human laryngeal epithelial cells in the presence of genistein, a tyrosine protein kinase inhibitor, decreased the invasion of these cells by b. bacilliformis significantly. further, exposure of normal human umbilical vein endothelial cells to staurosporine, a potent inhibitor of protein kinase c a ...199910077844
[prevalence of serum igg antibody against bartonella henselae in an asymptomatic japanese population]. 199910077908
[cat scratch disease]. 199910088350
[bartonellosis]. 199910088493
cat scratch disease diagnosed by polymerase chain reaction in a patient with suspected tuberculous lymphadenitis.we present a patient diagnosed as having tuberculous lymphadenitis after lymph node biopsy and referred for tuberculous therapy. on review, because of recent cat exposure, she was tested for cat scratch disease (csd), but serological tests for bartonella henselae were negative. however, the diagnosis of csd was confirmed, and tuberculosis excluded, by polymerase chain reaction techniques. this case serves as a reminder that csd may mimic tuberculosis histologically and that sensitive molecular d ...199910078182
the iala invasion gene of bartonella bacilliformis encodes a (de)nucleoside polyphosphate hydrolase of the mutt motif family and has homologs in other invasive bacteria.the product of the iala invasion gene of bartonella bacilliformis has been expressed as a thioredoxin fusion protein. it is a (di)nucleoside polyphosphate hydrolase of the mutt motif protein family with strong sequence similarity to plant diadenosine tetraphosphate hydrolases. it hydrolyses nucleoside and dinucleoside polyphosphates with four or more phosphate groups, always producing an ntp as one product. diadenosine tetraphosphate (ap4a) is the preferred substrate with a km of 10 microm and a ...199910080922
bartonella quintana in body lice collected from homeless persons in russia. 199910081691
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