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bartonella (rochalimaea) quintana infection in a seronegative hemodialyzed patient.bartonella quintana is a reemerging pathogen responsible for trench fever, endocarditis, bacteremia, and bacillary angiomatosis. we previously reported the first case of a patient with b. quintana-induced chronic adenomegaly, and here we present a report on a second patient. a hemodialyzed patient with sjögren's syndrome presented with mediastinal adenomegalies and secondary pancytopenia. all diagnostic investigations remained negative, except that a bartonella-like microorganism was isolated fr ...19968727894
bartonella (rochalimaea) henselae hepatosplenic infection occurring simultaneously in two siblings. 19968729220
[visceral localizations of cat-scratch disease in an immunocompetent patient].locoregional expression of cat scratch disease is well known, but despite advances in microbiology over the last 10 years leading to the description of two new bacteria (afipia felis, bartonella henselae) the infective agent responsible for cat scratch syndrome remains unknown. until the 80s, only one systemic disease was attributed to infection with a germ in the bartonella genus: trench fever. with the onset of the aids epidemic, new clinical syndromes caused by bartonella bacteria have been d ...19968729380
an analysis of lymph node dna for possible bacterial agents of cat-scratch disease.recent investigations have implicated afipia felis and rochalimaea henselae as possible agents of cat-scratch disease (csd). we studied lymph nodes with necrotizing granulomas characteristic of csd for a. felis and r. henselae dna so that the relationship of these organisms to lymph nodes with necrotizing granulomas of unknown etiology might be better defined. we examined formalin-fixed, paraffin-embedded lymph node biopsies with necrotizing granulomas suggestive of csd from 28 children obtained ...19958736593
an unusual presentation of cat scratch encephalitis.cat scratch disease is an infectious illness that has been recognized since the 1880s; however, our understanding and knowledge of it is still evolving (1). it was not until 1991 that the etiologic species, rochalimaea, was finally confirmed (2,3). only recently have the breadth of its clinical spectrum and the population at risk been appreciated. we now realize that signs and symptoms that had been considered cardinal for diagnosis may be absent. cat scratch disease was known to afflict primari ...19958747625
tropical medicine and bacteriology in boston and peru: studies of carrión's disease in the early twentieth century. 19968757718
bartonellosis in zamora chinchipe province in ecuador.human bartonellosis was investigated in the ecuadorian province of zamora chinchipe; 17 cases were identified retrospectively from hospital records over the period 1984-1995, mostly from 6 communities in the provincial district of zumba. a questionnaire concerning risk factors for disease transmission was administered in these 6 communities. blood samples were taken from individuals with current febrile illnesses or skin lesions suggestive of bartonellosis. samples for detection of bartonella ba ...19968758062
[cat scratch disease in immunocompetent children].first cause of chronic benign lymphadenopathy, cat scratch disease occurs mainly in children and young adults. the nature of its bacterial agents is not definitely established, but atlanta's cdc actually considers afipia felis and rochalimaea hensaela as the agents of the disease. it usually presents as chronic adenitis but there are severe forms of the disease with systemic manifestation. in such forms, new techniques such as serology and molecular biology are particularly useful for the diagno ...19968762962
bartonella species infections, including cat-scratch disease, trench fever, and bacillary angiomatosis--what molecular techniques have revealed. 19968779201
bartonella vinsonii subsp. berkhoffii subsp. nov., isolated from dogs; bartonella vinsonii subsp. vinsonii; and emended description of bartonella vinsonii.two bacterial strains, one isolated from the blood of a dog with valvular endocarditis and one isolated from the blood of a healthy dog, were similar to bartonella species, as determined by a number of phenotypic criteria, including growth characteristics, biochemical reactions, and cell wall fatty acid composition. the results of 16s rrna gene sequence similarity studies confirmed that these strains are closely related and belong in the genus bartonella and that bartonella vinsonii is their clo ...19968782679
granulomatous hepatitis and necrotizing splenitis due to bartonella henselae in a patient with cancer: case report and review of hepatosplenic manifestations of bartonella infection.bacillary angiomatosis and the related disorders of bacillary peliosis hepatis and bacillary splenitis are manifestations of infection with bartonella henselae and bartonella quintana in immunocompromised persons. b. henselae infection, but not b. quintana infection, is linked to contact with cats and is presumed to cause visceral cat-scratch disease. we reports a case of visceral infection by b. henselae in an adult patient with cancer who was receiving chemotherapy and had had no contact with ...19968783692
bartonella henselae infection in cats: evaluation during primary infection, treatment, and rechallenge infection.bartonella henselae infection was established in eight cats of various ages by experimental inoculation. all cats remained persistently bacteremic until they were treated 4 to 7 weeks after primary inoculation. antibody titers increased and peaked between 4 and 12 weeks for all cats. treatment with doxycycline for 1 week was effective in suppressing bacteremia in all cats but was effective in clearing infection from only four cats. amoxicillin, given subsequently, was effective in clearing the i ...19968784569
predominance of two bartonella henselae variants among cat-scratch disease patients in the netherlands.restriction endonuclease analysis of the pcr-amplified 16s-23s rrna gene spacer region was used to investigate the prevalence of bartonella henselae variants in samples from cat-scratch disease (csd) patients. analysis of spacer pcr fragments from 27 bartonella dna-positive samples from dutch patients with csd with alui revealed two restriction fragment length polymorphism (rflp) patterns, patterns a and b. twenty samples yielded b. henselae pattern a, and 7 samples yielded b. henselae pattern b ...19968788996
cat-scratch disease. 19968794184
the role of molecular techniques in the understanding of emerging infections.emerging infections are defined as infections that are newly identified or recognized, or those whose incidence in humans has significantly increased over the past 20 years. the interaction of several factors contributes to the emergence of infectious disease, including changes in human behavior, technological advances, economic development, increased international travel, microbial adaptation and lapses in public health measures. biomedical research has allowed us to identify and classify previ ...19968796869
multiple recurrent bacillary angiomatosis due to bartonella quintana in an hiv-infected patient. 19968801095
bartonella (rochalimaea) quintana infections.bartonella (formerly rochalimaea) quintana is the etiological agent of trench fever, a disease extensively reported during the world wars. recent molecular biology approaches have allowed dramatic extension of the spectrum of bartonella infections. b. quintana is now also recognized as an etiological agent of fever and bacteremia, endocarditis, bacillary angiomatosis, and chronic lymphadenopathy. human immunodeficiency virus-infected patients and/or homeless people are the most vulnerable to inf ...19968809460
comparative seroreactivity to bartonella henselae and bartonella quintana among cats from israel and north carolina.bartonella henselae, the predominant cause of cat scratch disease, and bartonella quintana, the cause of trench fever, are closely related bartonella species that induce cross-reactivity when cat or human sera are tested using an indirect immunofluorescence antibody (ifa) test. cats are the natural reservoir for b. henselae, whereas a mammalian reservoir host for b. quintana has not been identified. serum samples from 114 cats from israel and 114 cats from north carolina were tested by ifa for s ...19968810011
identification of bartonella henselae and b. quintana 16s rdna sequences by branch-, genus- and species-specific amplification.given the controversy surrounding the aetiology of cat scratch disease and the association of both bartonella henselae and b. quintana with bacillary angiomatosis, a method for the direct detection in clinical samples of 16s rrna from the proteobacteria alpha subgroup was developed. the primary structure of amplified 16s rdna was determined by cloning and sequencing. three sequences were identified: one corresponded exactly to genbank accession number m73229 (b. henselae); the second was related ...19968810946
experimental transmission of bartonella henselae by the cat flea.bartonella henselae is an emerging bacterial pathogen, causing cat scratch disease and bacillary angiomatosis. cats bacteremic with b. henselae constitute a large reservoir from which humans become infected. prevention of human infection depends on elucidation of the natural history and means of feline infection. we studied 47 cattery cats in a private home for 12 months to determine the longitudinal prevalence of b. henselae bacteremia, the prevalence of b. henselae in the fleas infesting these ...19968818889
bartonella henselae infection mimicking systemic onset juvenile chronic arthritis in a 2 1/2-year-old girl. 19968823702
the histologic spectrum of hepatic cat scratch disease. a series of six cases with confirmed bartonella henselae infection.cat scratch disease (csd), a common cause of regional lymphadenitis, has been linked to bartonella henselae infection. although rare, dissemination with hepatic involvement has been documented. six cases of hepatic csd were retrieved and probed for b. henselae dna. hematoxylin-eosin, trichrome, methenamine silver, gram, ziehl-neelsen, and warthin-starry stained slides were reviewed by all authors, and the histologic findings were recorded. b. henselae infection was confirmed in all cases using c ...19968827032
bacillary angiomatosis of the cervix and vulva in a patient with aids.bacillary angiomatosis is a clinicopathologic entity that most often is identified in the skin of patients with aids. this report presents an example of bacillary angiomatosis of the female genital tract.19968841262
prevalence of bartonella henselae antibodies among human immunodeficiency virus-infected patients from bahrain. 19968842286
image cytometry and topographical analysis of proliferation of endothelial cells in vitro during bartonella (rochalimaea) infection.bartonella quintana and bartonella henselae are clinically associated with proliferative neovascular lesions. the effect of bartonella infection on human endothelial cells was evaluated in vitro by quantitative image analysis. particular emphasis is placed on reporting the methodologies employed. human umbilical vein endothelial cells were infected in vitro with the two bartonella species. cell proliferation (cell density), cell morphology (cell surface, form and elongation factors) and spatial ...19968844102
diagnosis of 22 new cases of bartonella endocarditis.bartonella species are emerging pathogens that are seldom reported as a cause of blood culture-negative endocarditis.19968849149
bacillary angiomatosis associated with extensive esophageal polyposis: a new mucocutaneous manifestation of acquired immunodeficiency disease (aids).bacillary angiomatosis is a rare infection that has been associated with human immunodeficiency virus infection. the causative organism is rochalimaea henselae and contact with cats is a risk factor. we present a case of a 37-yr-old man who had recent prolonged exposure to a cat and presented with fever, iron deficiency anemia, and guaiac-positive stools who had biopsy-proven bacillary angiomatosis skin lesions and on esophagogastroduodenoscopy had multiple, diffuse, friable, polypoid lesions in ...19968855753
unsuspected hepatosplenic involvement in patients hospitalized with cat-scratch disease. 19968858685
intermediate uveitis and retinal vasculitis as manifestations of cat scratch disease.to study the ocular manifestations of systemic rochalimaea infection.19968862061
serological cross-reactions between bartonella quintana, bartonella henselae, and coxiella burnetii.the clinical manifestations of q fever and bartonelloses can be confused, especially in cases of infectious endocarditis. differential diagnosis of the diseases is important because the treatments required for q fever and bartonelloses are different. laboratory confirmation of a suspected case of either q fever or bartonelloses is most commonly made by antibody estimation with an indirect immunofluorescence assay. with an indirect immunofluorescence assay, 258 serum samples from patients with q ...19968862597
comparison of partial citrate synthase gene (glta) sequences for phylogenetic analysis of bartonella species.nucleotide base sequence data were obtained for a 940-bp fragment of the citrate synthase-encoding gene (glta) of representatives of the eight validly described bartonella species and seven uncharacterized bartonella strains obtained from small mammals. complete 16s rrna gene sequences were also determined for the uncharacterized strains, and these sequences revealed that each strain had a unique sequence which was very similar to the sequences of the previously recognized bartonella species. a ...19968863415
pathogenic mechanisms of bartonella henselae infections. 19968866818
bartonella bacilliformis: dangerous pathogen slowly emerging from deep background.bartonella bacilliformis was perhaps the most lethal bacterial human pathogen in the pre-antibiotic era, but infections were and are limited to a specific geographical area, largely in peru, corresponding to the range of its sand fly vector. b. bacilliformis targets both red cells and endothelial cells. recent phylogenetic realignments have revealed a close genetic relationship to other bacteria which cause human diseases, including bacterial angiomatosis, to the former grahamella species which ...19968870245
evaluation of an extended blood culture protocol to isolate fastidious organisms from patients with aids.recent reports of fastidious pathogens suggest the need for special blood cultures for immunocompromised patients. blood cultures from 45 human immunodeficiency virus (hiv)-infected patients with unexplained fever (> or = 38.0 degrees c) and cd4 counts of < 125 cells per mm3 were collected into a vacuum tube with sodium polyanetholsulfonate, an isolator tube, and bactec aerobic and anaerobic bottles. blood from the sodium polyanethosulfonate tube was inoculated into bactec 13a bottles, which wer ...19968880497
cat-scratch disease and bartonella henselae infections in children. 19968880885
cell entry and the pathogenesis of bartonella infections.erythrocyte parasitism, or hemotrophy, is not a common strategy for bacteria. however, bartonella species are elegantly adapted to parasitize a variety of cell types including red blood cells. bartonella bacilliformis, a useful model organism for the genus, has been used to study virulence determinants involved in colonization, attachment and invasion of host cells.19968885168
portal triad involvement in cat-scratch disease. 19968888205
evaluation of serological response to bartonella henselae, bartonella quintana and afipia felis antigens in 64 patients with suspected cat-scratch disease.the serological response to bartonella henselae, b. quintana, and afipia felis was assessed by an indirect fluorescence antibody test (ifat) in 64 patients with suspected cat-scratch disease (csd) recruited from the bordeaux area in france. blood samples were collected from 57 patients with chronic lymphadenopathy who underwent lymph-node biopsy with suggestive histopathologic features of csd, and from an additional 7 patients with suspected csd who underwent surgical incision and drainage becau ...19968893399
unraveling mysteries associated with cat-scratch disease, bacillary angiomatosis, and related syndromes.the search for the infectious agents responsible for cat-scratch disease, bacillary angiomatosis, and related syndromes has a long and often circuitous history. recognition of the etiologic agents and a new understanding of the fundamental features of the epidemiology and natural history of modern day bartonella (formerly rochalimaea)-associated diseases culminate a multipartite story that combines clinical medicine, traditional microbiology, and novel technological approaches to solve a long-st ...19958903149
emergence of bartonella quintana infection among homeless persons. 19968903217
will the real agent of cat-scratch disease please stand up?cat-scratch disease has been recognized since 1889 in association with the oculoglandular syndrome of parinaud. the epidemiologic association with cats was first made in 1931 and further substantiated throughout the years, refining the interaction predominantly to kittens. putative infectious agents have included numerous species of bacteria, chlamydiae, and viruses. the cultivation of afipia spp. in the late 1980s appeared to answer the mystery of the identity of the agent. however, even more r ...19968905096
bartonella infections and hiv disease.successful assessment and treatment of bartonella in hiv-seropositive people depends on nursing's fundamental role in the management of these bacterial infections. bartonella species are responsible for a variety of infections, including cat scratch disease and bacillary angiomatosis, which can be debilitating to people living with aids. this paper provides an overview of the clinical presentation and nursing management of bartonella infection in plwas. the author discusses common diagnostic pro ...19968906735
does coinfection of bartonella henselae and fiv induce clinical disorders in cats?it was found that bartonella henselae (b. henselae) may induce clinical disorders in cats in natural conditions from a comparison of the serological status for b. henselae with the serostatus for feline immunodeficiency virus (fiv) and several clinical characteristics in 170 domestic cats. seropositivity for b. henselae was not significantly different between fiv antibody-positive and -negative cats (18.4% vs 16.0%). the incidence of clinical characteristics were compared among four cat groups d ...19968908605
serological study of bartonella henselae in cat scratch disease in japan.it has become clear that bartonella henselae is a common cause of cat scratch disease (csd). the indirect fluorescence antibody (ifa) test for detection of igg and igm antibodies to b. henselae concerning csd showed that 5 (50%) of 10 patients with csd had a serum igg antibody titer of 1:128 or more and that 2 (20%) patients had a serum igm antibody titer of 1:20 or more. one of 7 asymptomatic members of patients' families (14%) had igg antibody to b. henselae at a titer of 1:256. igm antibody t ...19968908613
survey of the seroprevalence of bartonella quintana in homeless people.trench fever is caused by bartonella (rochalimaea) quintana, a small gram-negative rod that is transmitted by body lice. recently, b. quintana infections in homeless patients have been reported in the united states and europe. from october 1993 to october 1994, the seroprevalence of antibodies to b. quintana was assessed by indirect immunofluorescence in a prospective study of 221 nonhospitalized homeless people, 43 hospitalized homeless patients (cases), 250 blood donors, and 57 hospitalized ma ...19968909840
re: imaging features of cat-scratch disease. 19968911215
prevalence of bartonella henselae bacteremia, the causative agent of cat scratch disease, in an australian cat population.in order to determine the prevalence of bartonella henselae becteremia in an australian cat population we examined blood cultures on a group of sydney cats. cats referred to the concord animal hospital for euthanasia were selected randomly for blood culture and serum sampling. blood samples were lysed and centrifuged and then cultured for up to five weeks. suspicious colonies were identified biochemically as probable b. henselae. selected isolates were confirmed as b. henselae using the polymera ...19968912359
bacillary angiomatosis: microbiology, histopathology, clinical presentation, diagnosis and management.bacillary angiomatosis is known to be caused by a rickettsial organism; rochalimaea henselae. this causative agent has been compared with different microorganisms and clinical conditions that appear in similar settings but that have been clearly differentiated from them; e.i. cat-scratch disease (afipia felis), bartonella bacilliformis, other rochalimaea sp., kaposi;s sarcoma, lobular capillary hemangioma, angiosarcoma, and epithelioid hemangioma. clinically the bacillary angiomatosis (ba) skin ...19968916440
cloning, expression and sequence analysis of the bartonella henselae gene encoding the htra stress-response protein.a cloned fragment of bartonella (rochalimaea) henselae (bh) dna was found to direct synthesis of an immunoreactive protein in escherichia coli (ec). sequence analysis revealed an open reading frame of 1509 nucleotides encoding a protein of 503 amino acids that exhibited extensive identity (over the entire protein) with the htra stress-response proteins of brucella abortus (59%), ec (37%) and salmonella typhimurium (36%). when the putative htra gene was amplified by polymerase chain reaction and ...19968921888
isolation of bartonella quintana from an hiv-positive patient with bacillary angiomatosis.bartonella quintana was grown from a lysis-centrifugation blood culture of an hiv-positive man who presented with lesions of bacillary angiomatosis in skin and bones. the isolate was identified by sodium dodecylsulfate-polyacrylamide gel electrophoresis, 16s rrna gene sequencing, and amplification of the enterobacterial repetitive intergenic consensus sequences.19968922574
generalized infection with bartonella henselae following infection due to epstein-barr virus. 19968922830
[cat scratch disease. an overview for the ent physician].background: cat scratch disease (csd) is a relatively common cause of chronic lymphadenopathy in the usa. in the present paper the authors describe recent advances in the understanding of this disorder focusing on etiology, clinical aspects, diagnostic management, and therapy. etiology: rochalimaea henselae and afipia felis, two gram-negative bacteria, have recently been isolated from lymph node tissue of patients suffering from csd. the current literature reveals that rochalimaea henselae seems ...19968924168
[back again: the clothes louse (pediculus humanus var. corporis)].in two homeless men aged 38 and 32 years, who suffered from itching, infestation with body lice (pediculus humanus var. corporis, a.k.a. clothes lice) was diagnosed. this infestation is rare in the netherlands. in 1993 and 1994 and infection with body lice was registered 41 times in 31 patients at the clinic for homeless of the community health service of utrecht. the body louse can be seen by the naked eye. treatment is by hygienic measures, pediculicides if necessary, and by prevention. import ...19968927169
[endocarditis of negative blood culture: search in the intra-cell!]. 19968942948
antibodies to bartonella species in inner-city intravenous drug users in baltimore, md.bartonella quintana has recently been associated with homeless alcoholic men. both b quintana and bartonella henselae have been shown to be opportunistic pathogens of people with acquired immunodeficiency syndrome. the reservoirs and modes of transmission of these infections are incompletely known.19968944742
experimentally induced bartonella henselae infections followed by challenge exposure and antimicrobial therapy in cats.to elucidate kinetics of bartonella henselae bacteremia and igg response, evaluate antibiotic therapy, and investigate challenge exposure in cats.19968950424
cat scratch disease: detection of bartonella henselae dna in archival biopsies from patients with clinically, serologically, and histologically defined disease.serological and epidemiological studies suggest that bartonella henselae is the etiological agent of cat scratch disease. we designed a study to detect b. henselae in archival biopsies by polymerase chain reaction amplification of the 16s rrna gene followed by southern blot hybridization. forty-two histologically defined cat scratch disease biopsies and eighteen controls were selected for blinded analysis. after testing, charts were reviewed for clinical, immunological, and microbial evidence of ...19968952548
[illnesses caused by bartonella. cat-scratch disease, bacillary angiomatosis, bacillary peliosis hepatis, endocarditis]. 19968964682
[cat scratch disease in a 14-year-old boy]. 19968975226
[cat-scratch disease as a diagnostic problem of lymphadenopathy].the diagnosis of cat-scratch disease is based on history and clinical symptoms. we present a case of a 4-year-old girl admitted to our unit with suspicion of histiocytosis x after histologic evaluation of a submandibular lymph node biopsy. on the basis of history, clinical features and histologic reevaluation, the diagnosis of cat-scratch disease was made.19968975227
bacillary angiomatosis in an hiv seronegative patient on systemic steroid therapy.bacillary angiomatosis is an unusual systemic vascular proliferation seen predominantly in patients with the acquired immunodeficiency syndrome. these vascular lesions are due to infection with a bartonella species, most commonly b. henselae, but sometimes b. quintana. it is treatable and often curable, but without therapy may be life-threatening. clinically, the disorder often resembles several different vascular disorders, particularly pyogenic granuloma and kaposi's sarcoma. we now report a c ...19968977724
[cat-scratch disease in humans and the cat's role. causative agents finally isolated]. 19968984725
case records of the massachusetts general hospital. weekly clinicopathological exercises. case 2-1997. a 38-year-old man with digital clubbing, low-grade fever, and a murmur. 19978988901
parinaud's oculoglandular conjunctivitis and cat-scratch disease. 19968989598
bacillary angiomatosis in an immunocompetent child.bacillary angiomatosis (ba) is a pathological process characterized by prominent vascular proliferation secondary to organisms of the genus rochalimaea. ba has been most commonly associated with hiv-1+ patients, but has also been reported rarely in other immune-suppressed patients and in a small group of patients with no demonstrated immune suppression. even in immune-suppressed children, ba is extremely rare. we report a 5-year-old girl with no apparent immune suppression and no risk factors fo ...19968989932
maintenance of broad-host-range incompatibility group p and group q plasmids and transposition of tn5 in bartonella henselae following conjugal plasmid transfer from escherichia coli.the first demonstration of conjugal plasmid transfer from escherichia coli to bartonella henselae is reported. transconjugants bearing plasmids of incompatibility groups p (incp) and q (incq), expressing various resistance markers, were generated. tn5 transposons delivered on suicide plasmids by conjugation showed transpositional insertion into random chromosomal sites.19978990308
diagnostic value of the indirect immunofluorescence assay in cat scratch disease with bartonella henselae and afipia felis antigens.serum samples from 35 cat scratch disease (csd) patients, 180 control patients (123 without lymph node enlargement and 57 with lymph node enlargement not evoking csd), and 102 nonpatient subjects (35 with cat contact and 67 without cat contact) were tested by semiquantitative indirect immunofluorescence assay for the presence of antibodies directed to afipia felis (atcc 53690t) or bartonella henselae (atcc 49882t). the csd group had statistically higher antibody titers against b. henselae than t ...19968991636
redefining aids: towards a modification of the current aids case definition.aids is defined by the occurrence of an opportunistic infection or tumor considered indicative of advanced infection with human immunodeficiency virus (hiv). even though recent modifications have improved the widely used aids case definition issued by the world health organization and the centers for disease control and prevention, the modified version has fallen short of generating a globally functional instrument for the surveillance of hiv-related infections. the clinical aids case definition ...19978994765
[the epidemiology of trench fever: a pilot study in homeless people in marseilles].trench fever, cause by bartonella quintana, disappeared decades ago. between 1992 and 1994 about 20 cases were reported in industrialized countries [6, 7]. some of these cases were associated with hiv infection [5], but most affected the homeless. the epidemiology of b. quintana is unknown in europe, but infection and transmission are favoured by poor housing and hygiene. this paper describes the results of a seroprevalence survey among the homeless living in marseille. the eight major non-profi ...19968998590
the expanding spectrum of bartonella infections: i. bartonellosis and trench fever. 19979002093
experimental and natural infection with bartonella henselae in domestic cats.domestic cats were experimentally infected with culture propagated bartonella henselae by intradermal (i.d.) and intravenous (i.v.) routes. cats were more efficiently infected by the i.d. (8/8 cats) than by the i.v. (2/16) route. bacteremia was detected 1-3 weeks following inoculation and lasted for most cats for 1-8 months. however, one naturally infected cat was observed for 24 months and was found to be cyclically bacteremic, with bacterial levels varying one hundred fold or more from one per ...19979023040
the etest for antimicrobial susceptibility testing of bartonella henselae.the in-vitro susceptibility of 10 isolates of bartonella henselae was assessed using the etest. the organisms, one reference human strain and nine feline isolates, were grown on chocolate agar and the etests read at days 5, 8 and 11. six antibiotics, erythromycin, azithromycin, doxycycline, ciprofloxacin, rifampicin and vancomycin were evaluated. the results correlated well with published results using agar dilution. the results confirmed the high in-vitro susceptibility of b. henselae to erythr ...19969023643
cat-scratch disease and bacillary angiomatosis.cat-scratch disease (csd) was first described by debré in 1950, yet the causative bacterial agent of csd remained obscure until 1992, when bartonella (formerly rochalimaea) henselae was implicated in csd by serological and microbiological studies. b. henselae had initially been linked to bacillary angiomatosis (ba), a vascular proliferative disease most commonly associated with long-standing human immunodeficiency virus (hiv) infection or other significant immunosuppression. b. henselae has also ...19969025151
[rochalimaea and its role in human pathology]. 19969027188
bacillary angiomatosis: presentation of six patients, some with unusual features.bacillary angiomatosis (ba) is an unusual systemic vascular proliferation seen predominantly in patients with the acquired immunodeficiency syndrome. these vascular lesions are probably due to infection with a bartonella species, most often b. henselae and, in some patients, b. quintana. ba is treatable and often curable, but without therapy, may be life-threatening. clinically, the lesions, when superficial, are said to often resemble pyogenic granulomas, appearing polypoid histologically with ...19979039296
isolation of bartonella (rochalimaea) henselae: effects of methods of blood collection and handling.bartonella (rochalimaea) henselae causes cat-scratch disease, bacillary angiomatosis, peliosis hepatis, and fever in humans. b. henselae can be difficult to culture axenically, and as many as 5 weeks may be required before colonies are visible. we compared how different methods of blood collection and handling affect isolation of this pathogen. blood specimens from b. henselae-infected cats were collected in both edta and isolator blood-lysis tubes and were subsequently plated onto rabbit blood- ...19979041385
detection and identification of two bartonella henselae variants in domestic cats in germany.to determine the prevalence of bacteremia caused by bartonella henselae in domestic cats in the region of freiburg, germany, we investigated culture of blood from 100 cats from 89 different households over a 12-month period. b. henselae could be isolated from 13% (13 of 100) of these cats. in eight households with two cats each and in one household with three cats, b. henselae bacteremia was found either in all of the animals or in none of the animals. positive cultures were more likely to be fo ...19979041393
the expanding spectrum of bartonella infections: ii. cat-scratch disease.recent advancements and developments in molecular biotechnology have allowed more precise reclassification of many microorganisms. with the use of these new taxonomy tools, several organisms previously thought to belong to other genera have been recently described as bartonellae. of the 11 organisms now described as bartonella spp., only four have been shown to be pathogenic for humans. table 1 lists the four bartonella human pathogens along with the their known epidemiology and the scope and ra ...19979041596
in vitro susceptibilities of bartonella henselae, b. quintana, b. elizabethae, rickettsia rickettsii, r. conorii, r. akari, and r. prowazekii to macrolide antibiotics as determined by immunofluorescent-antibody analysis of infected vero cell monolayers.the in vitro susceptibilities of bartonella (rochalimaea) henselae, b. quintana, b. elizabethae, rickettsia akari, r. conorii, r. prowazekii, and r. rickettsii to different concentrations of azithromycin, clarithromycin, dirithromycin, erythromycin, and roxithromycin in vero cell cultures were evaluated. bartonella and rickettsia spp. were allowed to initiate infection of the antibiotic-free vero cell monolayers, which were maintained in 16-chamber microscope slides in the absence of antibiotics ...19979055996
survey of veterinary professionals and other veterinary conference attendees for antibodies to bartonella henselae and b quintana.to determine serologic and epidemiologic characteristics of an occupational group potentially at risk for bartonella sp infection.19979057914
acute multifocal retinitis.to describe the clinical presentation, ophthalmoscopic and fluorescein angiographic findings, and natural history of 14 eyes in nine otherwise healthy, young-to-middle-age adults with idiopathic, acute, multifocal retinitis.19979063244
[rochalimaea spp. infections and associated diseases]. 19969064385
hepatosplenic cat-scratch disease and abdominal pain.there have been several recent reports that cat-scratch disease (csd) causes a multiplicity of atypical clinical syndromes. we recently diagnosed hepatosplenic csd in a child who was seen with fever and abdominal pain. we report this case and 10 other patients with hepatosplenic csd and highlight the importance of abdominal pain in this clinical entity.19979076813
[cat-scratch disease. a report of 4 cases and a review of the literature].four cases of cat-scratch diseases are here reported and a review of the literature is made. the disease, apart from its typical presentation form as a usually self-limited regional lymph node enlargement, can occasionally spread and involve several organs systems. indirect immunofluorescence serological tests have been of help for its diagnosis and should be included among the diagnostic criteria for the disease. in particular cases, nuclear magnetic resonance can be useful to suggests the diag ...19979102668
cat-scratch disease and related clinical syndromes.bartonella (rochalimaea) henselae is a common cause of cat-scratch disease. this newly identified bacterium is also the cause of several other clinical syndromes, including bacillary angiomatosis, bacillary peliosis hepatitis and splenitis, and acute and relapsing bacteremia. a high percentage of young cats carry b. henselae. fortunately, serious complications of b. henselae infections are rare in immunocompetent patients. cat-scratch disease is usually a self-limited illness that does not neces ...19979105205
bartonella spp. as emerging human pathogens.members of the genus bartonella (formerly rochalimaea) were virtually unknown to modern-day clinicians and microbiologists until they were associated with opportunistic infections in aids patients about 6 years ago. since that time, bartonella species have been associated with cat scratch disease, bacillary angiomatosis, and a variety of other disease syndromes. clinical presentation of infection with bartonella ranges from a relatively mild lymphadenopathy with few other symptoms, seen in cat s ...19979105751
pathogenetic role of phagocytic abnormalities in human virus immunodeficiency infection: possible therapeutical approaches. a review.polymorphonuclear cells (pmn) and monocytes/macrophages (m/m) represent the first defence line against invading microorganisms. both phagocytic cell functions are precociously compromised in human immunodeficiency virus (hiv)-infected subjects, thus leading to infectious and neurological complications in the late stages of disease. among intracellular pathogens, emerging bacteria such as bartonella henselae and rhodococcus equi can cause peculiar clinical pictures, i.e. the bacillary parenchimal ...19979130002
histological and ultrastructural study of one case of oral bacillary angiomatosis in hiv disease and review of the literature.bacillary angiomatosis (ba) is a new clinicopathological entity defined as a pseudo-neoplastic capillary proliferation secondary to an opportunistic infection by one of two rochalimaea sp.: r. quintana or r. henselae. although ba is a recently recognised entity, numerous cases have been reported. most of the patients affected are reported to have low absolute cd4 lymphocyte counts associated with aids. yet, very few oral cases associated or not with cutaneous lesions have been reported or simply ...19949135977
epidemiologic evaluation of the risk factors associated with exposure and seroreactivity to bartonella vinsonii in dogs.to determine seroprevalence to bartonella vinsonii subsp berkhoffii in a population of sick dogs from north carolina and virginia and to evaluate potential risk factors associated with increased likelihood of exposure to the organism.19979140552
relapsing bacteremia after blood transmission of bartonella henselae to cats.to determine persistence of bacteremia, pathogenicity, and immunoglobulin kinetics after blood transmission of bartonella henselae in cats.19979140557
cat-scratch disease in a patient undergoing haemodialysis. 19979141021
a carboxy-terminal processing protease gene is located immediately upstream of the invasion-associated locus from bartonella bacilliformis.a gene with homology to those encoding an unusual class of c-terminal processing proteases that flanks the invasion-associated locus ialab of bartonella bacilliformis has been identified. the 1302 bp gene, termed ctpa, is located immediately upstream of the iala gene and encodes a predicted nascent product of 434 amino acids, producing a mature protein of 411 amino acid residues. the bartonella ctpa appears to undergo autolysis in vitro, producing multiple products of 43-46 kda, and a second gro ...19979141685
bacillary angiomatosis associated with myositis in a patient infected with human immunodeficiency virus.a man with aids presented with a deep soft-tissue mass involving the right thigh. biopsy of a skin lesion on the back and culture of a specimen from this lesion showed bacillary angiomatosis due to bartonella (formerly rochalimaea) quintana. magnetic resonance imaging revealed a large heterogeneous mass involving the vastus medialis and intermedius muscles. therapy with erythromycin caused rapid resolution of both the cutaneous lesion and the muscle lesion. bartonella infection is proposed as an ...19979145727
cat scratch disease in a child.we report a case of a 9-year-old girl scratched on the right side of her neck by a kitten about one month prior to admission. she was well until three weeks later when she developed enlarged right neck masses, a pustula on the scratch site, right injected conjunctiva, headache, general malaise and fever, thus fulfilling the clinical criteria for csd. initially, she was treated by a practicing physician but the manifestations persisted for one week. after admission, leukocytosis and a mildly elev ...19979151470
[2 patients with atypical manifestations of cat-scratch disease].in 2 boys aged 8 years and 10 months, respectively, uncommon manifestations of cat scratch disease were seen. the first patient had acute encephalopathy: coma and generalized tonic-clinic convulsions. the second patient was presented with fever and peripheral lymphadenopathy in combination with hypodense lesions in the liver on ultrasound. diagnosis was established on the clinical picture and the positive results of serological testing of antibody titres for bartonella henselae. both patients re ...19979157299
[visceral granulomas and pericardial effusion caused by a bartonella henselae infection].a 57 year-old woman was seen after a three-week period of upper abdominal pain, nausea, fever, headache and exertional dyspnoea. laboratory examination showed an elevated esr and serum gamma-gt activity. the chest x-ray showed cardiomegaly resulting from a pericardial effusion as was demonstrated by echocardiography. an abdominal ct-scan disclosed multiple hypodense lesions in the liver and spleen and lymphadenopathy along the hepatoduodenal ligament. liver biopsy showed a necrotising granulomat ...19979157300
cat scratch disease as a rare cause of obstructive jaundice: a case report. 19979157863
prevalence of bartonella henselae and bartonella clarridgeiae in stray cats.the aim of the present work was to determine by blood culture the prevalence of blood infection with bartonella species in a well-defined, european, urban stray cat population. therefore, 94 stray cats were trapped from 10 cat colonies. blood samples of these cats were cultured on both blood agar and liquid medium in order to raise the likelihood of bacterial detection. fifty blood samples (53%) gave a positive culture result for bartonella species. isolate identification was performed by sequen ...19979163438
seroprevalence of immunoglobulin g antibodies to bartonella henselae in cat owners. 19979177972
infective endocarditis due to unusual or fastidious microorganisms.infective endocarditis due to fastidious microorganisms is commonly encountered in clinical practice. some organisms such as fungi account for up to 15% of cases of prosthetic valve infective endocarditis, whereas organisms of the hacek group (haemophilus parainfluenzae, h. aphrophilus, and h. paraphrophilus, actinobacillus actinomycetemcomitans, cardiobacterium hominis, eikenella corrodens, and kingella kingae) cause 3% of community-acquired cases of infective endocarditis. special techniques a ...19979179137
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