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delayed exposure to infections and childhood lymphomas: a case-control study.delayed exposure to common infections during childhood, have been implied to cause strong immunological response to a single infectious agent that eventually triggers leukemogenesis. the aim of the present study was to investigate whether decreased exposure to infections, as reflected in a more seronegative spectrum to several common infectious agents, is associated with increased risk for the development of childhood lymphomas.200919169895
isolation or molecular detection of bartonella henselae and bartonella vinsonii subsp. berkhoffii from dogs with idiopathic cavitary effusions. 200919175739
back pain in a child caused by cat scratch disease. 200919209087
[prevalence igg antibodies against bartonella henselae in children with lymphadenopathy].bartonella henselae is a cat scratch disease's etiological agent which is usually manifestated as regional lymphadenopathy. in differential diagnosis of lymphadenopathy infections about etiology b. henselae are rarely taken into consideration. enlargement of lymph nodes observed in children more often than in adults are caused by bacterial, virus or parasitic factors. in this study immunoglobulines g class antibodies to b. henselae were determined among children with limphadenopathy. at 53 child ...200819209738
evolutional and geographical relationships of bartonella grahamii isolates from wild rodents by multi-locus sequencing analysis.to clarify the relationship between bartonella grahamii strains and both the rodent host species and the geographic location of the rodent habitat, we have investigated 31 b. grahamii strains from ten rodent host species from asia (japan and china), north america (canada and the usa), and europe (russia and the uk). on the basis of multi-locus sequencing analysis of 16s rrna, ftsz, glta, groel, ribc, and rpob, the strains were classified into two large groups, an asian group and an american/euro ...200919219487
infection and replication of bartonella species within a tick cell line.bartonella species are fastidious, gram negative bacteria, some of which are transmitted by arthropod vectors, including fleas, sandflies, and lice. there is very little information regarding the interaction and/or transmission capabilities of bartonella species by ticks. in the present study, we demonstrate successful infection of the amblyomma americanum cell line, aae12, by seven bartonella isolates and three candidatus bartonella species by electron or light microscopy. with the exception of ...200919242658
bartonellosis causing bilateral leber neuroretinitis: a case report.bartonella henselae is the causal agent of cat scratch disease and one variation in its presentation is leber neuroretinitis. the unilateral presence of exudation as a macular star and papilledema represent its most common presentation.200919253255
prevalence of bartonella henselae and bartonella clarridgeiae in cats and dogs in korea.blood, saliva, and nail samples were collected from 54 dogs and 151 cats and analyzed for the presence of bartonella henselae with a novel nested polymerase chain reaction (pcr) method. bartonella (b.) henselae was detected in feral cat blood (41.8%), saliva (44.1%), and nail (42.7%) samples. b. henselae was also detected in pet cat blood (33.3%), saliva (43.5%), and nail (29.5%) samples and in pet dog blood (16.6%), saliva (18.5%), and nail (29.6%) samples. nine samples were infected with b. cl ...200919255530
[clinical thinking and decision making in practice. a man with abdominal pain, weight loss and fever]. 200919256242
identification of bartonella henselae in an aborted equine fetus.this report describes the characterization of a bartonella henselae abortion in an equine fetus by gross, histologic, immunohistochemical, ultrastructural, and molecular methods. bartonella henselae can cause cat scratch disease, bacillary angiomatosis, bacillary peliosis, and endocarditis in humans and other animals. the bacterium has been isolated from several mammalian species but only recently from equids; however, it has not been linked to abortion in equids. an aborted equine fetus exhibit ...200919261640
molecular documentation of bartonella infection in dogs in greece and italy.this study reports the occurrence of "bartonella rochalimae" in europe and the presence of bartonella vinsonii subsp. berkhoffii genotypes ii and iii in dogs in southern italy and provides dna sequencing evidence of a potentially new bartonella sp. infecting dogs in greece and italy.200919261798
a longitudinal study of bartonella infection in populations of woodrats and their fleas.rodent-borne bartonellae have been identified as human pathogens. little is known about bartonella infections in woodrat hosts and their fleas and how woodrat-flea associations may affect the dynamics of bartonella infections. we collected blood samples and fleas from two species of woodrats (neotoma micropus and n. albigula) from santa fe county, nm, from 2002-2005. the most predominant flea species were orchopeas sexdentatus and o. neotomae. bartonella prevalence in woodrats was 64% overall, w ...200819263856
bartonella-like dna detected in ixodes tasmani ticks (acari: ixodida) infesting koalas (phascolarctos cinereus) in victoria, australia.a total of 42 ticks comprising ixodes tasmani (n = 41) and ixodes trichosuri (n = 1) were collected from wild koalas (phascolarctos cinereus) at the koala convention centre, philip island, victoria, australia and screened for the presence of bartonella using the target gene glta. bartonella-like dna was detected in 4 of the 19 pooled tick samples (21%). all positive ticks were male. analysis of partial sequences for the glta gene indicated the presence of a bartonella-related species similar to ...200919271994
dogs are more permissive than cats or guinea pigs to experimental infection with a human isolate of bartonella rochalimae.bartonella rochalimae was first isolated from the blood of a human who traveled to peru and was exposed to multiple insect bites. foxes and dogs are likely natural reservoirs for this bacterium. we report the results of experimental inoculation of two dogs, five cats and six guinea pigs with the only human isolate of this new bartonella species. both dogs became bacteremic for 5-7 weeks, with a peak of 10(3)-10(4) colony forming units (cfu)/ml blood. three cats had low bacteremia levels (< 200 c ...200919272295
prevalence of bartonella henselae antibodies in children and blood donors in croatia. 200919274430
ecological fitness and strategies of adaptation of bartonella species to their hosts and vectors.bartonella spp. are facultative intracellular bacteria that cause characteristic hostrestricted hemotropic infections in mammals and are typically transmitted by blood-sucking arthropods. in the mammalian reservoir, these bacteria initially infect a yet unrecognized primary niche, which seeds organisms into the blood stream leading to the establishment of a long-lasting intra-erythrocytic bacteremia as the hall-mark of infection. bacterial type iv secretion systems, which are supra-molecular tra ...200919284965
polymerase chain reaction for pathogen identification in persistent pediatric cervical lymphadenitis.to study routine culture-negative persistent cervical lymphadenitis in children treated surgically during a 10-year period (december 26, 1997, to october 1, 2007) at a single institution.200919289701
bacillary angiomatosis.an infection with bartonella henselae transmitted from domestic cats to humans by scratching normally leads to cat-scratch disease. when the human host has severe immunosuppression or hiv infection, the potentially life-threatening disease bacillary angiomatosis can develop. a 79-year-old man presented with livid-erythematous, angioma-like skin lesions. we considered a cutaneous infiltrate from his known chronic lymphocytic leukemia, merkel cell carcinoma, cutaneous metastases of internal tumors ...200919298547
a translocated protein of bartonella henselae interferes with endocytic uptake of individual bacteria and triggers uptake of large bacterial aggregates via the invasome.bartonella henselae enters human endothelial cells (ecs) by two alternative routes: either by endocytosis, giving rise to bartonella-containing vacuoles or by invasome-mediated internalization. only the latter process depends on the type iv secretion system virb/vird4 and involves the formation of cell surface-associated bacterial aggregates, which get engulfed by ec membranes in an f-actin-dependent manner, eventually resulting in their complete internalization. here, we report that among the v ...200919302579
[cat scratch disease with bone involvement: a case report and literature review].cat scratch disease is an infectious disease caused by bartonella henselae. most of the patients present with a lymphadenopathy associated with a local infection at the site of the cat scratch. disseminated infection is uncommon.200919303175
human bartonella infection and african sleeping sickness. 194619312505
ocular bartonellosis. 200919319232
cat scratch disease: clinical considerations for the pediatric dentist.cat scratch disease (csd), caused by bartonella henselae, is a self-limited chronic lymphadenopathy. it is transmitted commonly by a scratch or bite from cats or kittens. diagnosis of csd is often difficult, as it masquerades as other causes of cervical lymphadenopathy or submandibular gland pathology. the purpose of this paper was to report a unique case of a 6-year old male who had close contact with a domestic dog and developed csd which progressed to suppuration. after treatment with antibio ...200919320261
exotic small mammals as potential reservoirs of zoonotic bartonella spp.to evaluate the risk for emerging human infections caused by zoonotic bartonella spp. from exotic small mammals, we investigated the prevalence of bartonella spp. in 546 small mammals (28 species) that had been imported into japan as pets from asia, north america, europe, and the middle and near east. we obtained 407 bartonella isolates and characterized them by molecular phylogenetic analysis of the citrate synthase gene, glta. the animals examined carried 4 zoonotic bartonella spp. that cause ...200919331727
proteomic analysis of the bacterial pathogen bartonella henselae and identification of immunogenic proteins for serodiagnosis.bartonella henselae is a slow growing, fastidious and facultative intracellular pathogen causing cat scratch disease and vasculoproliferative disorders. to date, knowledge about the pathogenicity of this human pathogenic bacterium is limited and, additionally, serodiagnosis still needs further improvement. here, we investigated the proteome of b. henselae using 2-d sds-page and maldi-tof-ms. we provide a comprehensive 2-d proteome reference map of the whole cell lysate of b. henselae with 431 id ...200919333998
bartonella quintana coinfection in staphylococcus aureus endocarditis: usefulness of screening in high-risk patients? 200919344260
experimental infection of cats with bartonella henselae resulted in rapid clearance associated with t helper 1 immune responses.six cats were inoculated with bartonella henselae strains a and b, which were isolated from the same naturally infected cat. the numbers of cd4(+) cells decreased following the infection. the levels of bacteremia were significantly correlated with the expression levels of ifn-gamma mrna during the various stages of bacteremia and elimination of the bacteremia. furthermore, the lower levels of tnf-alpha mrna expression during the bacteremia related to the emergence of higher levels of bacteremia. ...200919348961
bartonellosis.bartonella spp are fastidious bacteria that occur in the blood of man and mammals; they are usually vector borne but can also be transmitted by animal scratches and bites. the bartonelloses of medical importance comprise carrión's disease, trench fever, cat-scratch disease, bacillary angiomatosis, and peliosis hepatis. carrión's disease, known as oroya fever in the acute phase and verruga peruana (peruvian wart) in its chronic form, has curious manifestations that, until recently, have been rest ...200919362689
molecular characterization of resistance to fluoroquinolones in bartonella henselae and bartonella quintana. 200919369272
isolation of bartonella vinsonii subsp. berkhoffii genotype ii from a boy with epithelioid hemangioendothelioma and a dog with hemangiopericytoma.in this report, we describe isolation of bartonella vinsonii subsp. berkhoffii genotype ii from a boy with epithelioid hemangioendothelioma and a dog with hemangiopericytoma. these results suggest that b. vinsonii subsp. berkhoffii may cause vasoproliferative lesions in both humans and dogs.200919369441
serological evidence of bartonella vinsonii lymphadenopathies in a child bitten by a dog. 200919374641
molecular detection of bartonella species in rodents from the lao pdr. 200919374642
prevalence of bartonella infection in cats and dogs in a metropolitan area, thailand.the prevalence of bartonella infection was studied in 312 cats and 350 dogs in the bangkok metropolitan areas, thailand, between june 2001 and february 2003. bartonella was isolated from 47 (16.3%) of 288 stray cats, but from none of the 24 pet cats studied. of the 47 bartonella-positive cats, 45 animals were infected with only b. henselae, one was infected with only b. clarridgeiae, and one with both b. henselae and b. clarridgeiae. 16s rrna typing showed that 40 cats were infected with b. hens ...200919379541
[positive polymerase chain reaction for bartonella henselae in conjunctival granuloma]. 200919384797
seroprevalence of toxoplasma gondii and concurrent bartonella spp., feline immunodeficiency virus, and feline leukemia virus infections in cats from grenada, west indies.toxoplasma gondii and bartonella spp. are zoonotic pathogens of cats. feline immunodeficiency virus (fiv) and feline leukemia virus (felv) are related to human immunodeficiency virus, and human leukemia virus, respectively; all of these viruses are immunosuppressive. in the present study, the prevalence of antibodies to t. gondi, bartonella spp., fiv, as well as felv antigen were determined in sera from 75 domestic and 101 feral cats (felis catus) from the caribbean island of grenada, west indie ...200919385716
[diagnostics of cat scratch disease and present methods of bartonellosis recognition--a case report].bartonella infections including cat scratch disease (csd) is a group of infectious diseases which are diagnosed sporadically. because of this fact the number of csd cases in poland is underestimated and their incidence is markedly lower in comparison to other european countries. the aim of our report is to present various diagnostic methods and possibilities on the basis of two cases with symptoms of csd. the efficiency of specific bartonella antibiotic therapy is also discussed.200919388519
identification of a bartonella species in the harbor seal (phoca vitulina) and in seal lice (echinophtirius horridus).to explore whether harbor seals (phoca vitulina) are exposed to bartonella spp., 35 seal lice (echinophtirius horridus) were collected from seven seals, during their rehabilitation period in the seal rehabilitation and research center at pieterburen, the netherlands. forty-eight spleen samples were collected during necropsies of other harbor seals that died during rehabilitation, or had stranded dead and were brought to the seal rehabilitation and research center for postmortem investigation. li ...200919402763
molecular epidemiology of feline and human bartonella henselae isolates.multiple locus variable number tandem repeat analysis was performed on 178 bartonella henselae isolates from 9 countries; 99 profiles were distributed into 2 groups. human isolates/strains were placed into the second group. genotype i and ii isolates shared no common profile. all genotype i isolates clustered within group b. the evolutive implications are discussed.200919402978
[embolic stroke as the first manifestation of bartonella henselae endocarditis in an immunocompetent patient]. 201019409676
distinct activities of bartonella henselae type iv secretion effector proteins modulate capillary-like sprout formation.the zoonotic pathogen bartonella henselae (bh) can lead to vasoproliferative tumour lesions in the skin and inner organs known as bacillary angiomatosis and bacillary peliosis. the knowledge on the molecular and cellular mechanisms involved in this pathogen-triggered angiogenic process is confined by the lack of a suitable animal model and a physiologically relevant cell culture model of angiogenesis. here we employed a three-dimensional in vitro angiogenesis assay of collagen gel-embedded endot ...200919416269
evidence of bartonella spp., rickettsia spp. and anaplasma phagocytophilum in domestic, shelter and stray cat blood and fleas, portugal. 200919416279
presence of bartonella spp. in ixodidae ticks. 200919416286
a confusing case of canine vector-borne disease: clinical signs and progression in a dog co-infected with ehrlichia canis and bartonella vinsonii ssp. berkhoffii.abstract : bartonella spp. are important pathogens in human and veterinary medicine, and bartonellosis is considered as an emerging zoonosis that is being reported with increasing frequency. of 22 known species and subspecies of bartonella, seven have been isolated from dogs, causing disease manifestations similar to those seen in human beings. the wide variety of clinical signs and the possible chronic progression of disease manifestations are illustrated in the case of an infected labrador ret ...200919426442
cross-contamination in the molecular detection of bartonella from paraffin-embedded tissues.the genus bartonella comprises a group of gram-negative, fastidious bacteria. because of diagnostic limitations of culture and serologic testing, polymerase chain reaction (pcr) has become a powerful tool for the detection of bartonella spp. in blood and tissue samples. however, because many wild and domestic animals harbor bartonella spp., transfer of bartonella dna during sample collection or histologic processing could result in false-positive pcr test results. in this study, we describe evid ...200919429988
first detection of rickettsia felis and bartonella clarridgeiae in fleas from laos. 200919438611
identification of mechanisms involved in iron and haem uptake in bartonella birtlesii: in silico and in vivo approaches. 200919438629
in vitro effect of bartonella birtlesii on mouse red cell viability. 200919438632
bartonella alsatica endocarditis in a french patient in close contact with rabbits. 200919438633
bartonella infections in italy. 200919438634
comparative medical features of canine and human bartonellosis. 200919438635
meningitis due to a "bartonella washoensis"-like human pathogen.we report the second human case of infection caused by an organism identified as the proposed bartonella species, "b. washoensis." the organism was isolated from a blood sample from a patient presenting with meningitis and early sepsis. oropsylla montana fleas were implicated as the vector for disease transmission in this case.200919439538
clinical aspects of bartonella infection in northern greece. 200919456804
serological and molecular detection of bartonella spp. in humans, cats and dogs from northern sardinia, italy. 200919456814
description of bartonella spp. infections in a general hospital of catalonia, spain. 200919456816
first isolation of bartonella bovis from animals in french guyana, south america. 200919456818
emerging bartonella in humans and animals in asia and australia.bartonella species, belonging to the alpha 2 subgroup of proteobacteria, have either been considered or established as potential human and mammal pathogens. five novel species of bartonella have been reported in thailand and australia. recently, three strains of b. tamiae were isolated from febrile illness patients in thailand, while b. australis was isolated from kangaroos, and b. coopersplainsensis, b. queenslandensis, and b. rattiaustraliensis were isolated from rats in australia. the 17 nove ...200919459536
high prevalence of tick-borne pathogens in dogs from an indian reservation in northeastern arizona.we evaluated the serological and molecular prevalence of selected organisms in 145 dogs during late spring (may/june) of 2005 and in 88 dogs during winter (february) of 2007 from the hopi indian reservation. additionally, in 2005, 442 ticks attached to dogs were collected and identified as rhipicephalus sanguineus. infection with or exposure to at least one organism was detected in 69% and 66% of the dogs in may/june 2005 and february 2007, respectively. exposure to spotted fever group (sfg) ric ...201019469667
bartonella as a cause of blood culture-negative endocarditis. description of five cases.there is evidence that bartonella is an etiologic factor in human endocarditis. the objective of this article was to describe cases of endocarditis due to bartonella observed at a tertiary-care hospital during 1995-2006. overall, 140 cases of infective endocarditis were seen, of which 10 were blood culture-negative endocarditis, with five being due to bartonella. in four cases, there had been contact with cats. only two patients had pre-existing cardiac valvular disease. three had extracardiac d ...200919480767
immunogenicity of bartonella henselae p26 in cats.cat scratch disease (csd) has an estimated prevalence of approximately 200,000 persons in the usa, and approximately 22,000 new cases occur annually. cats are the natural carriers of bartonella henselae, the agent for csd. zoonotic transmission of b. henselae can result in csd in immunocompetent humans and bacillary angiomatosis in immunosuppressed humans. infection in cats often goes undetected. development of a vaccine to prevent feline infection is warranted to reduce the prevalence of infect ...200919500857
[current state of the knowledge of bartonella infections].bartonella spp. are gram-negative bacteria localized in erythrocytes of vertebrate hosts. genus bartonella contains numerous recently described species, many of them are new and emerging arthropod-borne human pathogens. in addition to humans, bartonella spp. have also been isolated from a variety of domesticated (cats, dogs) and wild animals (carnivores, ruminants, rodents), which play a key role as reservoir hosts for these pathogens. the infectious process and the pathogenesis of bartonellosis ...200919522219
bartonella quintana in body lice and head lice from homeless persons, san francisco, california, usa.bartonella quintana is a bacterium that causes trench fever in humans. past reports have shown bartonella spp. infections in homeless populations in san francisco, california, usa. the california department of public health in collaboration with san francisco project homeless connect initiated a program in 2007 to collect lice from the homeless to test for b. quintana and to educate the homeless and their caregivers on prevention and control of louse-borne disease. during 2007-2008, 33.3% of bod ...200919523290
rapid and cost-effective identification of bartonella species using mass spectrometry.bacteria of the genus bartonella are emerging zoonotic bacteria recognized in a variety of human diseases. due to their poor chemical reactivity, these fastidious bacteria are poorly characterized using routine phenotypic laboratory tests. identification is usually achieved using molecular techniques that are time-consuming, expensive and technically demanding. recently, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof ms) has emerged as a new technique for ...200919528172
the differential interaction of brucella and ochrobactrum with innate immunity reveals traits related to the evolution of stealthy pathogens.during evolution, innate immunity has been tuned to recognize pathogen-associated molecular patterns. however, some alpha-proteobacteria are stealthy intracellular pathogens not readily detected by this system. brucella members follow this strategy and are highly virulent, but other brucellaceae like ochrobactrum are rhizosphere inhabitants and only opportunistic pathogens. to gain insight into the emergence of the stealthy strategy, we compared these two phylogenetically close but biologically ...200919529776
bartonella endocarditis: a pathology shared by animal reservoirsand patients.bartonellae were first recognized to cause endocarditis in humans in 1993 when cases caused by bartonella quintana, b. elizabethae, and b. henselae were reported. since the first isolation of bartonella vinsonii subspecies berkhoffii from a dog with endocarditis, this organism has emerged as an important pathogen in dogs and an emerging pathogen in people. subsequently, four types of b. vinsonii subsp. berkhoffii have been described, all of which have been associated with endocarditis in dogs. a ...200919538271
insights in bartonella host specificity.the genus bartonella comprises a unique group of emerging gram-negative, intracellular bacteria that can cause a long-lasting intraerythrocytic bacteremia in their reservoir hosts. in recent years, the widespread occurrence and diversity of these bacteria has been increasingly recognized. this has resulted in a dramatic expansion of the genus bartonella to 24 currently described species or subspecies, among which at least half have been associated with human disease. bartonella infections have b ...200919538272
epidemiology of bartonella infection in rodents and shrews in taiwan.during the period of august 2002 and november 2004, an epidemiological investigation for bartonella infection was conducted in small mammals in taiwan. using whole blood culture on chocolate agar plates, bartonella species were successfully isolated from 41.3% of the 310 animals tested. the isolation rate of bartonella species varied among different animal species, including 52.7% of the 169 rattus norvegicus, 28.6% of the 126 sucus murinus, 10% of the 10 rattus rattus and 66.7% of the three rat ...201019538457
plasmid-based system for high-level gene expression and antisense gene knockdown in bartonella henselae.six broad-host-range plasmid vectors were developed to study gene expression in bartonella henselae. the vectors were used to express a beta-galactosidase reporter gene in b. henselae and to generate antisense rna for gene knockdown. when applied to ompr, a putative transcription response regulator of b. henselae, this antisense rna gene knockdown strategy reduced bacterial invasion of human endothelial cells by over 60%.200919542333
uveitis: an emerging clinical form of bartonella infection. 200919548998
duplex pcr assay simultaneously detecting and differentiating bartonella quintana, b. henselae, and coxiella burnetii in surgical heart valve specimens.a duplex pcr (dpcr) assay was developed to simultaneously detect and differentiate bartonella quintana, bartonella henselae, and coxiella burnetii from surgical heart valve tissue specimens with an analytic sensitivity of 10 copies/reaction. among 17 specimens collected from patients with a clinical diagnosis of culture-negative endocarditis, 2, 4, and 2 were positive for b. quintana, b. henselae, and c. burnetii, respectively, by the dpcr assay, which matched the results obtained by universal b ...200919553582
isolation and genetic characterization of a bartonella strain closely related to bartonella tribocorum and bartonella elizabethae in israeli commensal rats.ten bartonella isolates were cultured from blood drawn from black rats (rattus rattus) captured in the tel aviv area. genetic characterization included amplification and sequencing of five gene fragments including the ribc, rpob, 16s, groel, and glta and the 16s-23s intergenic spacer region. sequence comparisons showed that all 10 isolates were identical in all genes studied comprising a total of 3,873 bp analyzed. the sequences of each of the partial genes analyzed indicated a high sequence sim ...200919556567
tick-borne zoonotic bacteria in ticks collected from central spain.the prevalence of tick-borne and related bacteria infecting adult ticks in central spain was assessed by molecular methods. six areas were sampled monthly during a 2-year longitudinal study. a total of 1,038 questing and 442 feeding ticks, belonging to eight different species, were tested. the most abundant species were hyalomma lusitanicum (54% of captures), followed by dermacentor marginatus (23%) and rhipicephalus sanguineus (10%). four human pathogens, including seven rickettsia species, ana ...200919556569
computed tomography and magnetic resonance imaging of cat-scratch disease: a report of two cases.cat-scratch disease (csd) is a bacterial infection that typically causes swelling of the lymph nodes. the patients usually have a history of being scratched, bitten, or licked by cats and often by kittens. understanding the characteristic radiological and clinical features may lead to a noninvasive diagnosis and prevent unnecessary invasive procedures. we report two cases of csd with computed tomography and magnetic resonance imaging showing nodules or masses of lymphadenopathy with subcutaneous ...200919559357
co-isolation of bartonella henselae and bartonella vinsonii subsp. berkhoffii from blood, joint and subcutaneous seroma fluids from two naturally infected dogs.this report describes the clinical presentation, isolation and treatment of two dogs naturally infected with bartonella henselae and bartonella vinsonii subsp. berkhoffii. chronic and progressive polyarthritis was the primary complaint for dog #1, from which b. henselae and b. vinsonii subsp. berkhoffii were cultured on three independent occasions from blood and joint fluid samples, despite administration of nearly 4 months of non-consecutive antibiotic therapy. a clinically atypical and progres ...200919560291
serum feline pancreatic lipase immunoreactivity concentration and seroprevalences of antibodies against toxoplasma gondii and bartonella species in client-owned cats.feline pancreatitis is a commonly suspected illness and it has been proposed that some cases of feline pancreatitis may be caused by infection with toxoplasma gondii or bartonella species. feline pancreatic lipase immunoreactivity (fpli) is a test performed on serum that is commonly combined with other clinical findings as an indirect aid in the diagnosis of pancreatitis. the purpose of this study was to determine if there are associations between fpli concentration and the presence of serum ant ...200919560385
disseminated infection with bartonella henselae in a lung transplant recipient.we present the case of a lung transplant recipient with disseminated infection with bartonella henselae. in non-immunosuppressed humans, the organism typically causes a local infection that manifests itself as regional lymphadenopathy. the role of the host immune response to b henselae is critical in preventing progression to systemic disease. only rare cases of bartonellosis in transplant recipients have been reported. we discuss aspects and difficulties of diagnosis and treatment of bartonello ...200919560704
[risk of infections among orienteers].research on orienteers is useful for assessing the risk of infections associated with physical activity in the forest. in this paper four types of infections are reviewed, and the efficacy of preventive initiatives is discussed.200919561657
"candidatus bartonella thailandensis": a new genotype of bartonella identified from rodents.bartonella species, intracellular parasite of erythrocytes and endothelial cells, are zoonotic pathogens of wild and domestic animals including rodents. many species of rodents are commensally infected with a few bartonella species in asia. however, there are only few reports on detection of bartonella in thailand. our objective was to detect the presence of bartonella species in rodents from thailand. among 247 rodents captured in five provinces from thailand we identified bartonella species us ...200919574002
run-off replication of host-adaptability genes is associated with gene transfer agents in the genome of mouse-infecting bartonella grahamii.the genus bartonella comprises facultative intracellular bacteria adapted to mammals, including previously recognized and emerging human pathogens. we report the 2,341,328 bp genome sequence of bartonella grahamii, one of the most prevalent bartonella species in wild rodents. comparative genomics revealed that rodent-associated bartonella species have higher copy numbers of genes for putative host-adaptability factors than the related human-specific pathogens. many of these gene clusters are loc ...200919578403
detection of bartonella spp. in wild rodents in israel using hrm real-time pcr.the prevalence of bartonella spp. in wild rodents was studied in 19 geographical locations in israel. one hundred and twelve rodents belonging to five species (mus musculus, rattus rattus, microtus socialis, acomys cahirinus and apodemus sylvaticus) were included in the survey. in addition, 156 ectoparasites were collected from the rodents. spleen sample from each rodent and the ectoparasites were examined for the presence of bartonella dna using high resolution melt (hrm) real-time pcr. the met ...200919595521
infective endocarditis by bartonella quintana masquerading as antineutrophil cytoplasmic antibody-associated small vessel vasculitis.the bartonella species have been recently recognized as important causative agents of culture-negative bacterial endocarditis. antineutrophil cytoplasmic antibodies (ancas) have been associated with the spectrum of idiopathic small vessel vasculitis. however, a variety of infections can result in a false-positive anca test, and especially subacute bacterial endocarditis (sbe) with the presence of ancas occasionally mimics the clinical manifestations of an anca-associated vasculitis such as skin ...200919602882
the bacteriology of salivary gland infections.the parotid gland is the salivary gland most commonly affected by inflammation. however, infection of the salivary glands can occur in any of the glands. the most common pathogens associated with acute bacterial infection are staphylococcus aureus and anaerobic bacteria. the predominant anaerobes include: anaerobic gram negative bacilli (eg, pigmented prevotella and porphyromonas); fusobacterium spp; and peptostreptococcus spp. in addition, streptococcus spp (including streptococcus pneumoniae) ...200919608044
[hepatic localization of cat scratch disease in an immunocompetent patient].the cat-scratch disease is a benign inoculation disease and a well-known cause of localized lymphadenopathy. visceral localizations are rare and occur mostly in immunocompetent patients.201019616394
[biological and molecular characteristics of a cat-borne bartonella clarridgeiae].to characterize a bartonella strain m9hn-shq from a blood culture of cat from henan province,china.200919621628
bartonella rochalimae and other bartonella spp. in fleas, chile. 200919624952
cat scratch disease: a diagnostic conundrum.we report the case of a patient who presented to a clinic for evaluation of inguinal lymphadenopathy. histology of the lymph nodes revealed micoabscess formation suggesting infection with lymphogranuloma venereum (lgv) or bartonella henselae--the causative agent in cat scratch disease (csd). the patient recalled no preceding animal exposure. clinical and serological findings initially suggested early lgv but convalescent serology supported csd. this serves as an important reminder that b. hensel ...200919625597
bartonella rattaustraliani sp. nov., bartonella queenslandensis sp. nov. and bartonella coopersplainsensis sp. nov., identified in australian rats.a total of 11 bartonella isolates were recovered from the blood of melomys, uromys and rattus species in australia and were characterized using phenotypic and genotypic methods. comparison of 16s rrna gene, ftsz, glta and 16s-23s rrna internal transcribed spacer region sequences from the isolates indicated that they formed three sequence similarity groups that were distinct from one another and from the currently recognized bartonella species. phylogenetic analysis based on alignment of concaten ...200919628592
diffusion-weighted magnetic resonance imaging in cervical lymphadenopathy: report of three cases of patients with bartonella henselae infection mimicking malignant disease.diffusion-weighted mr imaging is a potential technique for differentiation between benign and malignant lymph nodes. however, lympadenopathy caused by bartonella henselae infection showes low adc values in diffusion weighted mri as typically seen in malignant disease.200919636985
cat scratch disease with cervical vertebral osteomyelitis and spinal epidural abscess.cat scratch disease has variable clinical presentations and should be considered in the differential diagnosis of vertebral osteomyelitis and epidural abscess if there is a history of contact with cats. we report a 5-year-old boy with cat scratch disease who presented with painful torticollis and osteomyelitis of the cervical spine associated with an epidural abscess.200919654566
bartonella japonica sp. nov. and bartonella silvatica sp. nov., isolated from apodemus mice.two bacterial strains, fuji 18-1(t) and fuji 23-1(t), were isolated from the blood of the small japanese field mouse (apodemus argenteus) and the large japanese field mouse (apodemus speciosus), respectively, specimens of which were captured in the forest of mount fuji, japan. phenotypic characterization (growth conditions, incubation periods, biochemical properties and cell morphologies), dna g+c contents (40.1 mol% for strain fuji 18-1(t) and 40.4 mol% for strain fuji 23-1(t)) and sequence ana ...201019656930
cervical lymphadenopathy in childhood epidemiology and management.cervical lymphadenopathy (cl) is common in childhood. the aim of this study is to evaluate the etiology, follow-up, and treatment of persistent cl. the authors studied retrospectively 50 children with cl, hospitalized at the department of pediatrics and pediatrics surgery. patients underwent ultrasonography. thirty-six percent presented abnormal ultrasonographic image and underwent excisional biopsy. biopsies revealed 4 thyroglossal cysts, 3 branchial cysts, 1 hemangioma, 2 sebaceous cysts, 1 de ...200919657996
pestilence, persistence and pathogenicity: infection strategies of bartonella.it has been nearly two decades since the discovery of bartonella as an agent of bacillary angiomatosis in aids patients and persistent bacteremia and 'nonculturable' endocarditis in homeless people. since that time, the number of bartonella species identified has increased from one to 24, and 10 of these bacteria are associated with human disease. although bartonella is the only genus that infects human erythrocytes and triggers pathological angiogenesis in the vascular bed, the group remains un ...200919659429
the pathophysiology of the acute phase of human bartonellosis resembles aids.human bartonellosis is a south american anthroponosis caused by bartonella bacilliformis. the disease has an acute phase characterized by invasion of red blood cells by parasites, and consequent severe anemia; and a chronic phase presenting with benign vascular tumors. during the acute phase, affected individuals are prone to developing opportunistic infections with a variety of organisms similar to the ones seen in aids. after antibiotic treatment is instituted, a subgroup of patients may devel ...201019665314
[cat scratch disease--a diagnostic problem, case report].cat scratch disease as a possible cause of neck limphadenopathy.200919681487
real-time pcr strategy and detection of bacterial agents of lymphadenitis.the aim of this study was to compare 16 s rrna gene amplification and sequencing with a systematic real-time pcr assay screening strategy that includes all common known pathogens recovered from lymph node biopsy specimens. lymph node biopsy samples sent to our laboratory from january 2007 to december 2008 were tested in the study. lymph nodes were screened for the presence of any bacteria by pcr amplification and sequencing targeting the 16 s rrna gene and also by a specific real-time pcr strate ...200919685089
genomics of host-restricted pathogens of the genus bartonella.the alpha-proteobacterial genus bartonella comprises numerous arthropod-borne pathogens that share a common host-restricted life-style, which is characterized by long-lasting intraerythrocytic infections in their specific mammalian reservoirs and transmission by blood-sucking arthropods. infection of an incidental host (e.g. humans by a zoonotic species) may cause disease in the absence of intra-erythrocytic infection. the genome sequences of four bartonella species are known, i.e. those of the ...200919696500
recurrent osteomyelitis in a cat due to infection with bartonella vinsonii subsp. berkhoffii genotype ii. 200919709358
molecular detection of bartonella henselae and bartonella koehlerae from aortic valves of boxer dogs with infective endocarditis.cardiac aortic valves from five dogs that died from acquired infective endocarditis were retrospectively molecularly screened for bartonella infection. identification was carried out using pcr targeting four gene fragments (rpob, ribc, 16s rrna and glta), and the 16s-23s intergenic spacer (its). bartonella henselae dna was detected in aortic valve tissue from one boxer dog with moderate subaortic stenosis (sas). bartonella koehlerae dna was detected from the aortic valve of another boxer dog wit ...201019716241
bartonellosis as cause of death after red blood cell unit transfusion.the authors present the case of a young man with aplastic anemia who went into shock and died after several red blood cell unit transfusions. immunohematological studies did not show any abnormality and blood cultures from patients and blood bags were negative. the ultrastructural findings, allied with current scientific knowledge, permitted the diagnosis of bartonella sp. infection. in face of this diagnosis, two possibilities should be considered: the first one is that the patient was already ...200919728230
[neuroretinitis. clinical cases].evaluate the etiology and the most frequent funduscopic alterations of the neuroretinitis.200919728239
guidelines for the prevention and treatment of opportunistic infections among hiv-exposed and hiv-infected children: recommendations from cdc, the national institutes of health, the hiv medicine association of the infectious diseases society of america, the pediatric infectious diseases society, and the american academy of pediatrics.this report updates and combines into one document earlier versions of guidelines for preventing and treating opportunistic infections (ois) among hiv-exposed and hiv-infected children, last published in 2002 and 2004, respectively. these guidelines are intended for use by clinicians and other health-care workers providing medical care for hiv-exposed and hiv-infected children in the united states. the guidelines discuss opportunistic pathogens that occur in the united states and one that might ...200919730409
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