Publications

TitleAbstractYear
Filter
PMID
Filter
parasite interactions in natural populations: insights from longitudinal data.the physiological and immunological state of an animal can be influenced by current infections and infection history. consequently, both ongoing and previous infections can affect host susceptibility to another parasite, the biology of the subsequent infection (e.g. infection length) and the impact of infection on host morbidity (pathology). in natural populations, most animals will be infected by a succession of different parasites throughout the course of their lives, with probably frequent co ...200818474121
molecular evidence for bartonella spp. in cat and dog fleas from germany and france.nine hundred and fifty-two fleas were collected from 148 cats and 133 dogs at 18 widely distributed geographic locations in germany and france and examined for the presence of six different bartonella spp. (bartonella bacilliformis, bartonella clarridgeiae, bartonella elizabethae, bartonella henselae, bartonella quintana, bartonella vinsonii subsp. berkhoffii) by pcr. thirty-five specimens (3.7%) tested positive for either b. henselae (14 positive fleas) or b. clarridgeiae (21 positive fleas). d ...200818489542
infection-associated type iv secretion systems of bartonella and their diverse roles in host cell interaction.type iv secretion systems (t4sss) are transporters of gram-negative bacteria that mediate interbacterial dna transfer, and translocation of virulence factors into eukaryotic host cells. the alpha-proteobacterial genus bartonella comprises arthropod-borne pathogens that colonize endothelial cells and erythrocytes of their mammalian reservoir hosts, thereby causing long-lasting intraerythrocytic infections. the deadly human pathogen bartonella bacilliformis holds an isolated position in the barton ...200818489724
[infective endocarditis due to bartonella quintana].we present the clinical case of a man of 68 years who was admitted for dizziness and sensation of loss of conscience. the clinical examination revealed a body temperature of 37.5 degrees c and a murmur of mitral regurgitation. the echocardiogram showed a severe mitral regurgitation and left cavitie's dilatation; transesophageal echocardiogram showed a vegetation in the anterior leaflet of the mitral valve. in blood cultures grew a gram-negative bacteria identified as bartonella spp. a pcr demons ...200818499964
native valve endocarditis due to bartonella henselae in an immunocompetent man.culture-negative endocarditis accounts for 2.5-31% of all endocarditis cases and remains a diagnostic and therapeutic challenge. bartonella spp. has only recently been recognized as an important cause of culture-negative endocarditis. we report a case of bartonella henselae endocarditis occurring in an immunocompetent man who owned a cat and had previously been diagnosed with valvulopathy. diagnosis was made only after prolonged diagnostic work-up with serology and with pcr and subsequent sequen ...200818500601
use of bartonella adhesin a (bada) immunoblotting in the serodiagnosis of bartonella henselae infections.bartonella henselae causes a variety of human diseases (e.g. cat scratch disease and the vasculoproliferative disorders, bacillary angiomatosis and peliosis hepatis). the laboratory diagnosis of b. henselae infections is usually based on the detection of anti-b. henselae antibodies by an indirect immunofluorescence assay (ifa) which, unfortunately, suffers from a significant amount of cross-reactivity and hence is prone to deliver false-positive results. in this pilot study, we evaluated the use ...200818501673
first report of bartonella quintana endocarditis in japan.bartonella (rochalimaea) species are increasingly recognized as a cause of endocarditis, but the total number of cases remains low. especially, bartonella quintana endocarditis is very rare and there have been no reports in japan. a 66-year-old man was hospitalized because of dyspnea and fever. an echocardiogram showed severe mitral valve regurgitation, mild aortic valve regurgitation, and echogenic masses on the mitral and aortic valve. six sets of blood cultures were negative. replacement of t ...200818503234
rickettsial seroepidemiology among farm workers, tianjin, people's republic of china.high seroprevalence rates for anaplasma phagocytophilum (8.8%), coxiella burnetii (6.4%), bartonella henselae (9.6%), and rickettsia typhi (4.1%) in 365 farm workers near tianjin, people's republic of china, suggest that human infections with these zoonotic bacteria are frequent and largely unrecognized. demographic features of seropositive persons suggest distinct epidemiology, ecology, and risks.200818507907
high prevalence of fastidious bacteria in 1520 cases of uveitis of unknown etiology.the etiologic evaluation of uveitis is frequently unsuccessful when noninvasive methods are used. we conducted a prospective study to evaluate systematic screening for pathogens of uveitis. all patients with uveitis referred to the participating tertiary ophthalmology departments from january 2001 to september 2007 underwent intraocular and serum specimen collection. the standardized protocol for laboratory investigations included universal polymerase chain reaction (pcr)-based detection of any ...200818520326
[cat-scratch disease localisation in the parotid gland].cat scratch disease is an infection due to bartonella henselae. it is one of the principal causes of benign chronic adenopathy in children or young adults.200818533210
search for borrelia burgdorferi in kidneys of dogs with suspected "lyme nephritis"."lyme nephritis" is a poorly characterized condition associated with proteinuria and often fatal renal failure in dogs with serological evidence of infection with borrelia burgdorferi.200818564223
factors associated with the occurrence of epistaxis in natural canine leishmaniasis (leishmania infantum).canine leishmaniasis (canl) is a common cause of epistaxis in dogs residing in endemic areas. the pathogenesis of canl-associated epistaxis has not been fully explored because of the limited number of cases reported so far.200818564224
bartonella henselae: first reported isolate in a human in thailand.this is the first reported case of bacillary angiomatosis associated with bartonella henselae in thailand. the clinical, pathological, and microbiological findings are presented. the bacterium was isolated from a biopsy of skin lesions obtained on admission and identified by cellular morphology, characteristics of colonies on chocolate agar, extensive biochemical tests and 16s ribosomal dna sequencing.200818567451
analysis of a novel insect cell culture medium-based growth medium for bartonella species.human- and animal-pathogenic bartonella species are fastidious and slow-growing bacteria difficult to isolate and cultivate. we describe a novel, easy-to-prepare liquid medium for the fast and reliable growth of several bartonella spp. that does not affect bacterial protein expression patterns or interactions with host cells.200818567689
[cat scratch disease and other human infections caused by bartonella species].the different bartonella species can cause various human infections such as cat scratch disease, chronic bacteremia (homeless patient with nonspecific symptom), endocarditis, bacillary angiomatosis, peliosis, and carrion's disease. diagnostic approaches include serology, culture and molecular approaches. pcr is especially useful on lymph nodes biopsies from patients with cat-scratch disease and on valvular samples taken from culture-negative endocarditis. serology exhibits a very high sensitivit ...200818578430
human bartonellosis: seroepidemiological and clinical features with an emphasis on data from brazil - a review.bartonellae are fastidious gram-negative bacteria that are widespread in nature with several animal reservoirs (mainly cats, dogs, and rodents) and insect vectors (mainly fleas, sandflies, and human lice). thirteen species or subspecies of bartonella have been recognized as agents causing human disease, including b. bacilliformis, b. quintana, b. vinsonii berkhoffii, b. henselae, b. elizabethae, b. grahamii, b. washoensis, b. koehlerae, b. rocha-limaea, and b. tamiae. the clinical spectrum of in ...200818592096
detrimental effects of bartonella henselae are counteracted by l-arginine and nitric oxide in human endothelial progenitor cells.the recruitment of circulating endothelial progenitor cells (epcs) might have a beneficial effect on the clinical course of several diseases. endothelial damage and detachment of endothelial cells are known to occur in infection, tissue ischemia, and sepsis. these detrimental effects in epcs are unknown. here we elucidated whether human epcs internalize bartonella henselae constituting a circulating niche of the pathogen. b. henselae invades epcs as shown by gentamicin protection assays and tran ...200818595894
transmission of bartonella henselae by ixodes ricinus.bartonella spp. are facultative intracellular bacteria associated with several emerging diseases in humans and animals. b. henselae causes cat-scratch disease and is increasingly associated with several other syndromes, particularly ocular infections and endocarditis. cats are the main reservoir for b. henselae and the bacteria are transmitted to cats by cat fleas. however, new potential vectors are suspected of transmitting b. henselae, in particular, ixodes ricinus, the most abundant ixodid ti ...200818598628
bartonella quintana and coxiella burnetii as causes of endocarditis, india. 200818598654
prevalence and genetic diversity of bartonella species isolated from wild rodents in japan.here, we describe for the first time the prevalence and genetic properties of bartonella organisms in wild rodents in japan. we captured 685 wild rodents throughout japan (in 12 prefectures) and successfully isolated bartonella organisms from 176 of the 685 rodents (isolation rate, 25.7%). those bartonella isolates were all obtained from the rodents captured in suburban areas (rate, 51.8%), but no organism was isolated from the animals captured in city areas. sequence analysis of rpob and glta r ...200818606803
seroprevalence of bartonella henselae antibodies in blood donors in crete. 200818609206
a bioinformatic approach to understanding antibiotic resistance in intracellular bacteria through whole genome analysis.intracellular bacteria survive within eukaryotic host cells and are difficult to kill with certain antibiotics. as a result, antibiotic resistance in intracellular bacteria is becoming commonplace in healthcare institutions. owing to the lack of methods available for transforming these bacteria, we evaluated the mechanisms of resistance using molecular methods and in silico genome analysis. the objective of this review was to understand the molecular mechanisms of antibiotic resistance through i ...200818619818
molecular screening of bartonella species in rodents from south western spain.rodents (87 mus spretus and 10 rattus norvegicus) collected in a suburban area of seville (andalusia, spain) between september 2003 and april 2004 were tested by polymerase chain reaction for the presence of bartonella dna using primers amplifying a fragment of the 16s/23s rrna internal transcribed spacer (its). sequence analyses of the its of these bartonella demonstrated that rodents in this region harbored at least three strains: two bartonella genotypes detected in m. spretus, which clustere ...200818620508
bartonella: emerging pathogen or emerging awareness?the number of known bartonella species is rapidly growing. some of them are responsible for distinct infectious diseases and show different prevalence and antibiotic susceptibility profiles. not only have some vectors of bartonella not been fully characterized, but also intermediate hosts are actually much more numerous and diverse than previously thought. among these, dogs differ from cats because they tend to suffer an overt disease similar to humans, thus providing the base for a useful anima ...200918621561
inguinal lymphadenopathy due to bartonella henselae.the bacterium bartonella henselae causes cat scratch disease, a self-limited zoonotic disease which is common among children and adolescents. the most typical clinical presentation is a regional lymphadenopathy that commonly involves only a single node of cervical and axillary lymph nodes. inguinal localization is rarely described. we report a case of a 35-year-old caucasian male complaining of a painless right inguinal mass and slight fever. a diagnosis of bartonella henselae infection was made ...200818622149
immune thrombocytopenic purpura as a complication of bartonella henselae infection.immune thrombocytopenic purpura is an infrequent yet well-recognized complication of viral infections, such as mumps, rubella, varicella, cytomegalovirus, parvovirus and infectious monunucleosis by epstein-barr virus. some recent studies have described a possible association between henoch-schonlein purpura, a non-thrombocytopenic purpura, and seropositivity for bartonella henselae, but in the literature only sporadic case reports have described a severe immune thrombocytopenic purpura as a comp ...200818622151
the head of bartonella adhesin a is crucial for host cell interaction of bartonella henselae.human pathogenic bartonella henselae cause cat scratch disease and vasculoproliferative disorders (e.g. bacillary angiomatosis). expression of bartonella adhesin a (bada) is crucial for bacterial autoagglutination, adhesion to host cells, binding to extracellular matrix proteins and proangiogenic reprogramming via activation of hypoxia inducible factor (hif)-1. like the prototypic yersinia adhesin a, bada belongs to the class of trimeric autotransporter adhesins and is constructed modularly cons ...200818627378
low sensitivity of bartonella henselae pcr in serum samples of patients with cat-scratch disease lymphadenitis. 200818628513
bartonella sp. bacteremia in patients with neurological and neurocognitive dysfunction.we detected infection with a bartonella species (b. henselae or b. vinsonii subsp. berkhoffii) in blood samples from six immunocompetent patients who presented with a chronic neurological or neurocognitive syndrome including seizures, ataxia, memory loss, and/or tremors. each of these patients had substantial animal contact or recent arthropod exposure as a potential risk factor for bartonella infection. additional studies should be performed to clarify the potential role of bartonella spp. as a ...200818632903
coinfection with four genera of bacteria (borrelia, bartonella, anaplasma, and ehrlichia) in haemaphysalis longicornis and ixodes sinensis ticks from china.we studied coinfection with four genera of bacteria--borrelia, bartonella, anaplasma, and ehrlichia--in ticks collected between december 2005 and november 2006 from zhejiang province and liaoning province. four hundred fifty haemaphysalis longicornis and 86 ixodes sinensis ticks were collected and divided into 236 groups. polymerase chain reaction (pcr) or nested pcr was used to detect the bacteria. the amplicons were sequenced and compared to published sequences. phylogenic analysis was perform ...200818637722
serum cardiac troponin i concentration in dogs with ehrlichiosis.ehrlichiosis is a multisystemic disease with the potential to cause cardiomyocyte injury in naturally infected dogs.200818638021
cat scratch disease complicated with aseptic meningitis and neuroretinitis.cat scratch disease (csd) is a self limited condition characterized by fever, lymph node enlargement and less often eye involvement. central nervous system involvement by bartonella henselae infection is possibly an important cause of morbidity; its role as an agent of aseptic meningitis is unknown. we report a case of a 40 years-old man with csd accompanied by aseptic meningitis and neuroretinitis. serum indirect immmunofluorescence (ifi) assays for b. henselae were positive and the cerebrospin ...200818641856
ocular bartonella infections. 200818645403
possible donor-recipient bartonellosis transmission in a pediatric liver transplant.bartonella henselae is the causative agent of cat-scratch disease and other disorders, including hepatosplenic granulomatosis. this infection has only rarely been reported after solid organ transplantation, where it can mimic the more common post-transplant lymphoproliferative disease. here we present a case of asymptomatic b. henselae hepatic and lymph nodal granulomatosis in a pediatric patient who had received orthotopic liver transplant 2 months before; we hypothesize that the causative agen ...200818651873
serological evidence for the association of bartonella henselae infection with arrhythmogenic right ventricular cardiomyopathy.arrhythmogenic right ventricular cardiomyopathy (arvc) is an important cause of sudden death in young adults. on the basis of histopathological findings its pathogenesis may involve both a genetic origin and an inflammatory process. bartonella henselae may cause endomyocarditis and was detected in myocardium from a young male who succumbed to sudden cardiac death.200818666174
evaluation of an in-house cat scratch disease igm elisa to detect bartonella henselae in a routine laboratory setting.cat scratch disease (csd) is caused by bartonella henselae infection and is a common cause of regional lymphadenopathy. the diagnosis of csd largely depends on serology, but detection of b. henselae in an affected lymph node by pcr is also an important diagnostic tool. we evaluated an igm in-house elisa protocol and analyzed its performance in routine csd serology. serum samples from pcr-positive patients (n = 126), pcr-negative patients (n = 123), and age-matched controls (n = 126) were used fo ...200918679728
structure of the head of the bartonella adhesin bada.trimeric autotransporter adhesins (taas) are a major class of proteins by which pathogenic proteobacteria adhere to their hosts. prominent examples include yersinia yada, haemophilus hia and hsf, moraxella uspa1 and a2, and neisseria nada. taas also occur in symbiotic and environmental species and presumably represent a general solution to the problem of adhesion in proteobacteria. the general structure of taas follows a head-stalk-anchor architecture, where the heads are the primary mediators o ...200818688279
[bilateral panuveitis with serous retinal detachment].a 45-year-old patient with cat scratch disease presented with bilateral panuveitis as well as bilateral serous detachment of the retina. the patient had suffered from influenza with swollen lymph nodes 2 weeks previously.200918696078
[ocular bartonellosis in an hiv-hvc coinfected patient].bartonella henselae is the etiologic agent of the cat scratch disease and in immunocompromised patients, of bacillary angiomatosis and peliosis hepatis. less often, ocular complications associated with b. henselae infection have been reported in immunocompetent patients and five times in hiv-infected patients. we report the case of a 42-year-old woman, coinfected by hiv-hcv, presenting with cirrhosis, who owned a cat and was hospitalized for bilateral loss of visual acuity. ophthalmologic examin ...200818706780
failure to identify an association between serologic or molecular evidence of bartonella infection and idiopathic rhinitis in dogs.to determine whether infection with or exposure to bartonella spp was associated with idiopathic rhinitis in dogs.200818710315
bartonella endocarditis mimicking adult still's disease.we describe the case of a 39-year-old caucasian woman who was admitted to the university hospital of antwerp with a clinical picture suggestive of adult still's disease. even though a transoesophageal echocardiography showed endocarditis of the aortic valve, blood cultures remained negative. additional serological testing revealed a positive result for bartonella henselae. histology of the supraclavicular lymph node showed a reactive lymph node with a positive polymerase chain reaction (pcr) for ...200818714850
microbial pathogens in ticks, rodents and a shrew in northern gyeonggi-do near the dmz, korea.a total of 1,618 ticks [420 individual (adults) and pooled (larvae and nymphs) samples], 369 rodents (apodemus agrarius, rattus norvegicus, tscherskia triton, mus musculus, and myodes regulus), and 34 shrews (crocidura lasiura) that were collected in northern gyeonggi-do near the demilitarized zone (dmz) of korea during 2004-2005, were assayed by pcr for selected zoonotic pathogens. from a total of 420 individual and pooled tick dna samples, anaplasma (a.) phagocytophilum (16), a. platys (16), e ...200818716449
bartonella species detection in captive, stranded and free-ranging cetaceans.we present prevalence of bartonella spp. for multiple cohorts of wild and captive cetaceans. one hundred and six cetaceans including 86 bottlenose dolphins (71 free-ranging, 14 captive in a facility with a dolphin experiencing debility of unknown origin, 1 stranded), 11 striped dolphins, 4 harbor porpoises, 3 risso's dolphins, 1 dwarf sperm whale and 1 pygmy sperm whale (all stranded) were sampled. whole blood (n = 95 live animals) and tissues (n = 15 freshly dead animals) were screened by pcr ( ...200818721502
cat-scratch disease of the head and neck in a pediatric population: surgical indications and outcomes.to identify the presentation of pediatric patients with head and neck manifestations of cat-scratch disease, one of the most common causes of subacute or chronic lymphadenitis in children, and to determine surgical indications and outcomes.200818722212
p26-based serodiagnosis for bartonella spp. infection in cats.bartonella henselae p26 has been identified as an immunodominant antigen expressed during feline infection. we used antisera from cats experimentally infected with b. henselae (n = 6), b. clarridgeiae (n = 4), or b. koehlerae (n = 2) and from a sample of naturally infected cats (b. henselae, n = 34; b. clarridgeiae, n = 1) to evaluate recombinant p26 (rp26) as a serodiagnostic antigen. immunoblots using antisera from cats infected with b. henselae and b. clarridgeiae reacted strongly with rp26, ...200818724780
laboratory maintenance of bartonella quintana.trench fever is the common name for the acute febrile syndrome associated with a bartonella quintana bacterial infection. the focus of this unit is to describe reliable methods for cultivation and cryopreservation of b. quintana and can be applied to cultivation and preservation of all bartonella. detailed recipes for preparation of three types of semisolid media are also included.200818729057
simultaneous presence of two different copies of the 16s rrna gene in bartonella henselae.bartonella henselae is an emerging pathogen of increasing medical significance. previous investigations have revealed two different 16s rrna gene variants among b. henselae isolates, resulting in delineation of the b. henselae population into 16s rna type i and type ii isolates. while studying 191 b. henselae isolates by multi-locus sequence typing (mlst) we detected three isolates that could not be assigned to a distinct 16s rna type upon direct sequencing because of ambiguous nucleotides in a ...200818757822
preventing and controlling emerging and reemerging transmissible diseases in the homeless.homelessness is an increasing public health problem. because of poor living conditions and limited access to healthcare systems, homeless persons are exposed to many communicable infections. we summarize the intervention measures reported to be efficient for the control and the prevention of common transmissible infections among homeless populations. evidence suggests that appropriate street- or shelter-based interventions for targeted populations are the most efficient methods. depending on the ...200818760000
prevalence of bartonella species antibodies and bartonella species dna in the blood of cats with and without fever.the purpose of this study was to determine whether there are associations between bartonella species antibody (enzyme-linked immunosorbent assay (elisa) and western blot (wb)) and polymerase chain reaction assay results in cats with and without fever. afebrile control cats (39/93; 42.0%) were more likely to have bartonella species antibodies than cats with fever (29/93; 31.2%). the difference in prevalence of bartonella species deoxyribonucleic acid (dna) in blood of cats with fever (14/81; 17.3 ...200918760647
[interaction of bacteria of the genus bartonella with the host: inhibition of apoptosis, induction of proliferation, and formation of tumors].the bacteria of the genus bartonella are the causative agents for earlier not diagnosed or re-emergent diseases of the humans, danger of which increases in relation with increasing number of persons with the disturbed immune status. bartonellae are intracellular parasites, the places of their habitation in the humans and animals are the endothelial cells of blood vessels and erythrocytes. the modern data concerning major factors of the bartonellae virulence and host-bacteria interactions were co ...200818763333
the janus face of bartonella quintana recognition by toll-like receptors (tlrs): a review.bartonella quintana (b. quintana) is a facultative, intracellular bacterium, which causes trench fever, chronic bacteraemia and bacillary angiomatosis. little is known about the recognition of b. quintana by the innate immune system. in this review, we address the impact of toll-like receptors (tlrs) on the recognition of b. quintana and the activation of the host defense. when experimental models using human mononuclear cells, transfected cho cells, or tlr2-/- and tlr4-/- mice were used, differ ...200818775802
neuroretinitis secondary to concurrent infection with cat scratch disease and lyme disease. 200918791545
microbial culture of blood samples and serologic testing for bartonellosis in cats with chronic rhinosinusitis.to assess the role of bartonella spp in chronic rhinosinusitis (crs) by determining detection rates for the organism by serologic testing and microbial culture of blood samples for bartonella spp in cats with crs and control cats (cats with other nasal diseases, cats with systemic illnesses, and healthy cats).200818828717
optimization of pulse-field gel electrophoresis for bartonella subtyping.bartonella is a significant human pathogen and is the world's most common bacterial zoonosis acquired from companion animals. however, there is no uniform method for pulse-field gel electrophoresis (pfge) for bartonella population genetics studies. further, some genes of bartonella can mutate frequently and may affect the use of pfge for bartonella. here we designed methods to solve these problems. we standardized the bacterial concentration, selected the appropriate digestion enzyme, optimized ...200918835302
urban trench fever presenting as culture-negative endocarditis.a young russian man presented with increasing shortness of breath and signs of worsening aortic regurgitation. a diagnosis of infective endocarditis was made before emergency valve replacement. the infective cause was not discovered by routine culture but was suggested by electron microscopy and confirmed by serology and pcr testing.200918835881
[the diagnosis of cat-scratch-disease-associated adenitis: diagnostic value of serology and polymerase chain reaction].the diagnosis of cat scratch disease (csd) associated adenitis relies classically on the association of clinical, epidemiological and bacteriological criteria. the polymerase chain reaction (pcr) looks like a more competitive diagnostic trial than serology. we evaluated the sensitivity, specificity and predictive positive and negative values of serology in routine diagnosis of csd. a retrospective study over five years was led among patients presenting a suspicion of csd and having a serology an ...200818842353
cat scratch disease presenting as acute encephalopathy.an unusual case of primary meningo-encephalitis followed by partial complex seizure in a 9-year-old boy was found to be a symptom of cerebral bartonella henselae infection or cat scratch disease. despite one clinical relapse at 4 weeks post-presentation, he remained seizure free on carbamazepine for one year. six months after stopping carbamazepine, however, he developed deja vu phenomena and absence seizures with eeg abnormality. restarting carbamazepine improved his symptoms.200818843081
infective endocarditis due to bartonella quintana: a challenging diagnostic entity.bartonella quintana is a gram-negative microorganism, which may lead to infective endocarditis especially in compromised patients. the major concern about this pathogen is the diagnosis and detection. furthermore, the treatment of the infection has been a challenge for physicians. in this report, we present a 71-year-old patient with bartonella quintana aortic valve endocarditis from the view of diagnosis and treatment aspects.200818795592
[cat scratch disease: a diagnosis to be aware of!].subacute cervical lymphadenopathy among young adults may be of an infectious or malignant aetiology. we report two cases of young males with chronic cervical lymphadenopathy. a diagnosis of cat scratch disease (csd) was made by serological and molecular studies. csd is one of the most frequent infectious lymphadenopathies among young people. diagnosis of csd is dependent on clinical, epidemiological, molecular and histological criteria. the detection of antibodies to bartonella henselae and the ...200818777770
bartonella bacilliformis anemia (oroya fever); a study of 30 cases. 194818875365
[not available]. 194818878133
[not available]. 194718921688
bartonella henselae survives after the storage period of red blood cell units: is it transmissible by transfusion?bartonella henselae is the agent of cat scratch disease and bacillary angiomatosis. blood donors can be asymptomatic carriers of b. henselae and the risk for transmission by transfusion should be considered. the objective of this study was to demonstrate that b. henselae remains viable in red blood cell (rbc) units at the end of the storage period. two rbc units were split into two portions. one portion was inoculated with b. henselae and the other was used as a control. all units were stored at ...200818937735
pathogen screening and bionomics of lutzomyia apache (diptera: psychodidae) in wyoming, usa.phlebotomine sand flies are vectors of bacteria, parasites, and viruses. lutzomyia apache, a north american sand fly, was incriminated as a vector of vesicular stomatitis viruses (vsv) due to overlapping ranges of the sand fly and recent outbreaks of vsv. we report on the discovery of 2 populations of l. apache in wyoming from albany and fremont counties. we attempted to isolate vsv and phleboviruses from sand flies from albany county and screened select flies by polymerase chain reaction for ba ...200818939699
balb/c mice resist infection with bartonella bacilliformis.bartonellosis due to bartonella bacilliformis is a highly lethal endemic and sometimes epidemic infectious disease in south america, and a serious public health concern in perú. there is limited information on the immunologic response to b. bacilliformis infection. the objective of this research was to produce experimental infection of balb/c mice to b. bacilliformis inoculation.200818957122
bartonella henselae in captive and hunter-harvested beluga (delphinapterus leucas).previously, we reported the isolation of bartonella henselae from the blood of harbor porpoises (phocoena phocoena) and loggerhead sea turtles (caretta caretta) from the north carolina coast. hematologic, pathologic, and microbiologic findings surrounding the death of a juvenile captive beluga in vancouver initiated an outbreak investigation designed to define the molecular prevalence of bartonella infection in belugas. using polymerase chain reaction analyses targeting the intergenic spacer reg ...200818957643
ectoparasites and associated pathogens of free-roaming and captive animals in zoos of south carolina.a survey of ectoparasites and their associated pathogens was conducted in two south carolina zoos, from 2004 to 2007. dead, wild birds and mammals, as well as captive animals examined during routine veterinary checks constituted the study populations. ectoparasites were tested for species of anaplasma, bartonella, coxiella burnetii, ehrlichia, rickettsia, and trypanosoma. forty-six species of ectoparasites were collected from 133 free-roaming and captive hosts and their associated nesting and be ...200918973443
function, regulation, and transcriptional organization of the hemin utilization locus of bartonella quintana.bartonella quintana is a gram-negative agent of trench fever, chronic bacteremia, endocarditis, and bacillary angiomatosis in humans. b. quintana has the highest known hemin requirement among bacteria, but the mechanisms of hemin acquisition are poorly defined. genomic analyses revealed a potential locus dedicated to hemin utilization (hut) encoding a putative hemin receptor, huta; a tonb-like energy transducer; an abc transport system comprised of three proteins, hutb, hutc, and hmuv; and a hem ...200918981245
first known case of bartonella quintana endocarditis in sweden.in this report, we present the first known case of bartonella endocarditis in sweden. igg antibody titres to bartonella spp. were elevated but blood cultures remained negative. sequencing of a glta fragment from dna extracted from heart valve tissue specimens revealed sequence homology with b. quintana.200918985544
investigation of bartonella henselae in cats in ankara, turkey.the purpose of this study was to determine bartonella henselae prevalance in cats in ankara. whole bloods and sera collected from 256 cats were investigated for the presence feline bartonella species by culture and sera were tested for the presence of antibodies against b. henselae igg using immunofluorescence assay. bartonella species were isolated by blood culture from 24 (9.4%) cats. bartonella isolates were subjected to restriction fragment length polymorphism (rflp) by using taqi and hhai e ...200918990198
hepatosplenic cat-scratch fever with seropositivity for bartonella quintana? 200818992392
incidence of various tick-borne microorganisms in rodents and ticks of central slovakia.in this study, we detected rickettsia helvetica, candidatus midichloria mitochondrii, anaplasma phagocytophilum, ehrlichia muris, candidatus neoehrlichia mikurensis, and bartonella sp. infections in wild rodents and ticks collected from the vegetation of central slovakia. the microorganisms were identified by pcr and sequencing. yellow-necked mice (apodemus flavicollis) were infected with e. muris and bartonella sp., while ticks ixodes ricinus collected from the vegetation were infected with r. ...200818999892
bartonella henselae: subversion of vascular endothelial cell functions by translocated bacterial effector proteins.bartonella henselae (bh) is a worldwide distributed zoonotic pathogen. depending on the immune status of the infected individual this bacterium can cause a wide spectrum of clinical manifestations, ranging from cat scratch disease (csd) to bacillary angiomatosis (ba) and bacillary peliosis (bp). ba and bp are characterized by tumor-like lesions at the skin or in the inner organs, respectively. these structures display pathological sprouting of capillaries with enlarged and hyperproliferated vasc ...200919010441
isolation of bartonella species from rodents in taiwan including a strain closely related to 'bartonella rochalimae' from rattus norvegicus.an increasing number of bartonella species originally isolated from small mammals have been identified as emerging human pathogens. during an investigation of bartonella infection in rodent populations carried out in taiwan in 2006, a total of 58 rodents were tested. it was determined that 10.3 % (6/58) of the animals were bartonella bacteraemic. after pcr/rflp analysis, four isolates were identified as bartonella elizabethae and one isolate as bartonella tribocorum. however, there was one speci ...200819018019
pcr detection of bartonella bovis and bartonella henselae in the blood of beef cattle.although an organism primarily associated with non-clinical bacteremia in domestic cattle and wild ruminants, bartonella bovis was recently defined as a cause of bovine endocarditis. the purpose of this study was to develop a b. bovis species-specific pcr assay that could be used to confirm the molecular prevalence of bartonella spp. infection. blood samples from 142 cattle were tested by conventional pcr targeting the bartonella 16s-23s intergenic spacer (its) region. overall, bartonella dna wa ...200919019574
hemoplasma infection in hiv-positive patient, brazil.hemotrophic mycoplasmas infect a variety of mammals. although infection in humans is rarely reported, an association with an immunocompromised state has been suggested. we report a case of a mycoplasma haemofelis-like infection in an hiv-positive patient co-infected with bartonella henselae.200819046522
bartonella henselae antibodies after cat bite. 200819046527
human case of bartonella alsatica lymphadenitis. 200819046532
bartonella spp. and rickettsia felis in fleas, democratic republic of congo. 200819046544
development of an immunoglobulin m capture-based enzyme-linked immunosorbent assay for diagnosis of acute infections with bartonella henselae.we describe the development of an immunoglobulin m-specific enzyme-linked immunosorbent assay for the detection of an early antibody response to bartonella henselae, the causative agent of cat scratch disease, bacillary angiomatosis, and endocarditis. this assay discriminates between b. henselae-positive and -negative patient samples with sensitivity and specificity values of 100% and 97.1%, respectively.200919052161
seroprevalence of bartonella spp. in the endangered island fox (urocyon littoralis).bartonella clarridgeiae-like strains, presently b. rochalimae, were isolated in gray foxes (urocyon cinereoargenteus) in mainland california. the objective of this study was to investigate the presence of bartonella infection in the endangered island fox (urocyon littoralis) found only on the channel islands off the californian coast. between 2001 and 2004, 263 serum samples were collected. antibodies against bartonella vinsonii subsp. berkhoffii (bvb) and b. clarridgeiae (bc) were detected usin ...200919058928
seroprevalence of toxoplasma gondii and bartonella spp. antibodies in cats from pennsylvania.toxoplasma gondii and bartonella spp. are zoonotic pathogens of cats. in the present study, the prevalence of antibodies to t. gondii and bartonella spp. were determined in sera from 210 domestic cats from bensalem, pennsylvania. using a modified agglutination test, antibodies to t. gondii were found in 41 (19.5%) of the 210 cats with titers of 1:25 in 4, 1:50 in 9, 1:100 in 7, 1:200 in 3, 1:400 in 3, 1:800 in 5, 1:1,600 in 4, and 1:3,200 or higher in 6. for t. gondii, seroprevalence increased w ...200919061304
cat scratch disease with encephalopathy in a 9-year-old girl. 200819067901
[not available]. 194718919319
the prevalence of bartonella, hemoplasma, and rickettsia felis infections in domestic cats and in cat fleas in ontario.the prevalence of persistent bacteremic bartonella spp. and hemoplasma infections was determined in healthy pet cats in ontario. blood samples from healthy cats sent to a diagnostic laboratory for routine health assessment over the course of 1 y were tested for bartonella spp. using both polymerase chain reaction (pcr) and blood culture, and for the presence of hemoplasma by pcr. the overall prevalence of bartonella spp. by pcr and by culture combined was 4.3% (28/646) [3.7% (24/646) bartonella ...200819086373
myocarditis due to bartonella henselae. 200819088543
[infective endocarditis due to bartonella henselae following a rupture of a cerebral aneurysm].we report a case of severe aortic bicuspid valve endocarditis, revealed by global cardiac failure without fever, in a 38-year-old man who had developed cerebral mycotic aneurysms nine months earlier. pcr analysis of the excised aortic valve and serological tests (even 9 months earlier) were positive for bartonella henselae. a combination of intravenous then oral doxycyclin at 200mg/day and intravenous gentamycin at 90mg/day was given for 6 and 2 weeks respectively. the evolution was favorable on ...200919097835
[microbiological diagnosis of emerging bacterial pathogens: anaplasma, bartonella, rickettsia, and tropheryma whipplei].ehrlichia/anaplasma, bartonella, rickettsia and tropheryma whipplei (formerly called whippelii) are fastidious bacterial organisms, considered the causative agents of potentially severe emerging and re-emerging diseases with repercussions on public health. the recent availability of advanced molecular biology and cell culture techniques has led to the implication of many of these species in human pathologies. these issues are extensively covered in number 27 of the seimc microbiological procedur ...200819100178
infective endocarditis in a dog and the phylogenetic relationship of the associated "bartonella rochalimae" strain with isolates from dogs, gray foxes, and a human.the first case of canine endocarditis caused by "bartonella rochalimae" is reported. by pcr-restriction fragment length polymorphism, sequence, and phylogenetic analyses, bartonella isolates from a dog with endocarditis, 22 gray foxes, and three dogs, described as b. clarridgeiae like, were confirmed to belong to the new species "b. rochalimae," suggesting canids as the natural reservoir.200919109472
isolation of candidatus bartonella melophagi from human blood.candidatus bartonella melophagi was isolated by blood culture from 2 women, 1 of whom was co-infected with b. henselae. partial 16s rrna, rna polymerase b, and citrate synthase genes and 16s-23s internal transcribed spacer sequences indicated that human isolates were similar to candidatus b. melophagi.200919116054
zoonotic bartonella species in fleas collected on gray foxes (urocyon cinereoargenteus).bartonella spp. are fastidious, gram-negative, rod-shaped bacteria and are usually vector-borne. however, the vector has not been definitively identified for many recently described species. in northern california, gray foxes (urocyon cinereoargenteus) are infected with two zoonotic bartonella species, b. rochalimae and b. vinsonii subsp. berkhoffii. fleas (range 1-8 fleas per fox) were collected from 22 (41.5%) of 54 gray foxes from urban and backcountry zones near hoopa, california. the flea s ...200919125660
major histocompatibility complex (mhc) heterozygote superiority to natural multi-parasite infections in the water vole (arvicola terrestris).the fundamental role of the major histocompatibility complex (mhc) in immune recognition has led to a general consensus that the characteristically high levels of functional polymorphism at mhc genes is maintained by balancing selection operating through host-parasite coevolution. however, the actual mechanism by which selection operates is unclear. two hypotheses have been proposed: overdominance (or heterozygote superiority) and negative frequency-dependent selection. evidence for these hypoth ...200919129114
isolation and characterization of bartonella quintana from the parotid gland of an immunocompetent man.we describe a case of the isolation of bartonella quintana from the parotid gland of an apparently healthy man. pathological examination showed intraparotid granulomatous abscessual lymphadenitis. diagnosis was made on the basis of high titers of immunoglobulin g (igg) and igm antibodies and of culture isolation of a causative agent from parotid aspirate.200919129406
bartonella clarridgeiae in a cat in the uk. 200919136687
anemia in rats infested with bartonella muris and injected with pteroylglutamic acid. 194818907621
[infective endocarditis due to bartonella quintana]. 200819147434
pcr survey of vectorborne pathogens in dogs living in and around barcelona, an area endemic for leishmaniasis.blood samples from 153 dogs living in and around barcelona were assayed for leishmania infantum and ehrlichia, anaplasma, rickettsia, bartonella, hepatozoon, babesia and theileria species by pcr amplification of dna, and the amplicons obtained were sequenced. the prevalence of the infectious agents was l infantum (29.4 per cent), ehrlichia and anaplasma species (4.0 per cent), hepatozoon canis (3.3 per cent), babesia canis vogeli (2.0 per cent), babesia gibsoni (2.0 per cent), babesia canis cani ...200919168881
delayed exposure to infections and childhood lymphomas: a case-control study.delayed exposure to common infections during childhood, have been implied to cause strong immunological response to a single infectious agent that eventually triggers leukemogenesis. the aim of the present study was to investigate whether decreased exposure to infections, as reflected in a more seronegative spectrum to several common infectious agents, is associated with increased risk for the development of childhood lymphomas.200919169895
isolation or molecular detection of bartonella henselae and bartonella vinsonii subsp. berkhoffii from dogs with idiopathic cavitary effusions. 200919175739
back pain in a child caused by cat scratch disease. 200919209087
Displaying items 2001 - 2100 of 2611