Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| interaction of bartonella henselae with endothelial cells results in rapid bacterial rrna synthesis and replication. | bartonella henselae is a slow-growing microorganism and the causative pathogen of bacillary angiomatosis in man. here, we analysed how interaction of b. henselae with endothelial cells might affect bacterial growth. for this purpose, bacterial rrna production and ribosome content was determined by fluorescence in situ hybridization (fish) using rrna-targeted fluorescence-labelled oligonucleotide probes. b. henselae grown on agar plates showed no detectable rrna content by means of fish, whereas ... | 2000 | 11207598 |
| phylogenetic position of bartonella vinsonii subsp. arupensis based on 16s rdna and glta gene sequences. | the nucleotide sequences of the genes encoding 16s rrna and citrate synthase (glta) from a recently described member of the genus bartonella, bartonella vinsonii subsp. arupensis, isolated from mice and from the blood of a patient suffering from bacteraemia, were determined and compared with sequences of the 16s rdna and glta genes of other members of the genus bartonella in order to determine its relative phylogenetic position. b. vinsonii subsp. arupensis appeared to be closely related to b. v ... | 2001 | 11211257 |
| [cat-scratch disease]. | we report a case of fourteen years old boy with cat scratch disease. he was treated at pediatric clinic in january and february 2000. cat scratch disease is benign infectious chronic disease which appears in all ages. it begins after contact with cat and its scratch. yearly incidence of this disease for whole population is 0.77-0.86/100.000. the cause is bacillus bartonella which is also called genus rochalimaea. it is gram negative, mobile, aerobe bacillus with ten flagellas on one pole. our pa ... | 2000 | 11219917 |
| [ecological aspects of human pathogens ehrlichia and bartonella]. | the review presents data on the natural circulation of bartonellas and erlichias with the participation of lice, fleas, mosquitoes, ixodes ticks, as well as rodents, large wild mammals, and domestic animals. it outlines the human infection routes that are mainly associated with the attack of infected carriers and with the contacts with different warm-blooded animals. the risk of bartonellosis spread is evidenced by the data showing that 12.3% of clothes lice collected from homeless individuals i ... | 1999 | 11220997 |
| infection with bartonella weissii and detection of nanobacterium antigens in a north carolina beef herd. | very recently, bartonella organisms have been isolated from large ruminants (deer, elk, and dairy and beef cattle) located in the united states and in france. in this study, we report the serologic, microbiologic, and molecular findings related to the isolation of a bartonella species in north carolina beef cattle and the detection of nanobacterial antigen using a commercially available enzyme-linked immunosorbent assay. between august 1998 and september 1999, blood was collected from 38 cattle ... | 2001 | 11230398 |
| [seroimmunologic monitoring of microorganisms of rickettsia and bartonella species microorganisms in the moscow region]. | serological study of 788 blood sera, taken from residents of the moscow region was conducted using antigens of microorganisms of the genera rickettsia and bartonella. the first group under examination consisted of 355 patients with diagnosed diseases of nonreckettsial nature. the second group includes 433 healthy adults working at a meat processing and packing factory. the main method used for sera survey was the indirect immunofluorescence test. in the sera taken from the first group of subject ... | 2001 | 11236493 |
| detection of fastidious bacteria in cardiac valves in cases of blood culture negative endocarditis. | the diagnosis of blood culture negative endocarditis is still a problem. fastidious bacteria such as bartonella and coxiella are responsible for cases of blood culture negative endocarditis, the identification of which is mainly based on serological and dna studies only available in specialised centres. therefore, a routine technique is needed in surgical pathology laboratories to detect these bacteria in cardiac valve tissue sections. this report describes a staining technique, the gimenez stai ... | 2001 | 11253139 |
| a serological survey of rural dogs and cats on the southwestern canadian prairie for zoonotic pathogens. | a survey for antibodies against agents of plague, tularemia, and rocky mountain spotted fever (rmsf), and against sin nombre hantavirus (snv), bartonella henselae and b. clarridgeiae was conducted in the summer of 1995 using serum from rural dogs and cats living in the vicinity of four public parks in southeastern alberta and southwestern saskatchewan. antibodies to all pathogens were detected in all survey areas. overall prevalence rates were 0.075 for yersinia pestis, 0.089 for francisella tul ... | 2001 | 11257996 |
| formation of stress fibres in human endothelial cells infected with bartonella bacilliformis is associated with altered morphology, impaired migration and defects in cell morphogenesis. | bartonella bacilliformis, a gram-negative, flagellated bacterium, infects human erythrocytes (haematic phase) and endothelial cells (tissue phase), resulting in a biphasic disease. in the tissue phase of disease (verruga peruana), infection leads to infection of endothelial cells and a pronounced proliferation of these cells, resulting in characteristic skin eruptions of papules and nodules. we have studied the properties of endothelial cells infected in vitro. extensive cytoskeletal remodelling ... | 2001 | 11260140 |
| [bartonella henselae infection in domestic cat and dog fleas]. | we studied on the infection of domestic cat and dog fleas with bartonella henselae by polymerase chain reaction (pcr). a total of 62 fleas (36 ctenocephalidis felis from cats, 24 c. felis from dogs and 2 ctenocephalidis canis from dogs), stored in 70% ethanol, were analyzed by pcr for b. henselae specific dna. of the 62 fleas, c. felis from cats and dogs were positive for b. henselae specific dna in 12 of the 36 (33.3%) and in 5 of the 24 (20.8%), respectively, and c. canis from dogs was positiv ... | 2001 | 11260879 |
| [subacute infectious endocarditis due to the agent of cat scratch fever: bartonella henselae]. | the diagnosis of severe mitral stenosis with left atrial thrombus was rectified at valvular replacement in a 48-year old immuno-competent man who was a cat owner. the mass in the left atrium was, in fact, a large endocarditic vegetation. pre- and postoperative blood cultures were negative as was culture of the excised mitral valve. the diagnosis of infectious endocarditis (ie) due to bartonella henselae was made from a positive serological test (1600) and identification of the germ by genetic am ... | 2001 | 11265556 |
| prevalence of bartonella henselae in cats in the uk. | 2001 | 11266008 | |
| genomic diversity of bartonella henselae isolates from domestic cats from japan, the usa and france by pulsed-field gel electrophoresis. | the genomic dna diversity of 27 bartonella henselae and three b. clarridgeiae isolates from 18 domestic cats from japan, the usa and france was investigated by pulsed-field gel electrophoresis (pfge) with noti, asci and smai restriction enzymes. a great diversity of genomic patterns was found for all b. henselae, but none for b. clarridgeiae isolates. the dna size of b. henselae and b. clarridgeiae isolates were 1.7-2.9 and 1.7mbp, respectively. all 13 japanese cat isolates were identified as b. ... | 2001 | 11267793 |
| molecular evidence of bartonella spp. in questing adult ixodes pacificus ticks in california. | ticks are the vectors of many zoonotic diseases in the united states, including lyme disease, human monocytic and granulocytic ehrlichioses, and rocky mountain spotted fever. most known bartonella species are arthropod borne. therefore, it is important to determine if some bartonella species, which are emerging pathogens, could be carried or transmitted by ticks. in this study, adult ixodes pacificus ticks were collected by flagging vegetation in three sites in santa clara county, calif. pcr-res ... | 2001 | 11283031 |
| epidemiology of bartonella infection in domestic cats in france. | blood samples were collected between february and june 1996 from a convenience sample of 436 domestic french cats living in paris and its environs and were tested for bartonella bacteremia and seropositivity. seventy-two cats (16.5%) were bartonella bacteremic, of which 36 cats (50%) were infected with bartonella henselae type ii (b.h. ii) only, 15 cats (21%) were infected with bartonella clarridgeiae (b.c.) only, and 11 cats (15%) were infected with b. henselae type i (b.h. i) only. eight cats ... | 2001 | 11295338 |
| giant hepatic granuloma caused by bartonella henselae. | we report a 10-year-old girl with a 3.0- by 3.5-cm giant hepatic granuloma caused by bartonella henselae. such a solitary and large granuloma associated with b. henselae infection has not been previously reported. we believe that b. henselae infection is a consideration in the differential diagnosis of a large hepatic mass. | 2001 | 11303841 |
| an update on human bartonelloses. | the data available on bartonella species has increased rapidly in the last decade with 12 new species and subspecies being described and bartonellas being found to be associated with an increasing spectrum of clinical syndromes in immunocompetent and immunocompromised patients. in addition b. weissii is found in cats. this rapid expansion of knowledge has come about with the development of new culture and molecular biology techniques to isolate and identify the organisms. much of the information ... | 2000 | 11317589 |
| asymptomatic persistent pulmonary infiltrates in an immunocompetent boy with cat-scratch disease. | we describe here an immunocompetent boy with fever, regional adenopathy, multifocal hepatosplenic granulomas, and high and increasing serum antibody titers for bartonella henselae in whom diffuse bilateral reticulonodular pulmonary infiltrates developed in the absence of respiratory symptoms. | 2001 | 11317652 |
| assessing the association between the geographic distribution of deer ticks and seropositivity rates to various tick-transmitted disease organisms in dogs. | to determine whether the geographic distribution of deer ticks (ixodes scapularis) was associated with the distribution of dogs seropositive for various tick-transmitted disease organisms (ie, borrelia burgdorferi, rickettsia rickettsii, the human granulocytic ehrlichiosis [hge] agent, ehrlichia canis, and bartonella vinsonii subsp berkhoffii). | 2001 | 11318358 |
| trem-1 amplifies inflammation and is a crucial mediator of septic shock. | host innate responses to bacterial infections are primarily mediated by neutrophils and monocytes/macrophages. these cells express pattern recognition receptors (prrs) that bind conserved molecular structures shared by groups of microorganisms. stimulation of prr signalling pathways initiates secretion of proinflammatory mediators, which promote the elimination of infectious agents and the induction of tissue repair. excessive inflammation owing to bacterial infections can lead to tissue damage ... | 2001 | 11323674 |
| detection and culture of bartonella quintana, serratia marcescens, and acinetobacter spp. from decontaminated human body lice. | as part of a survey for trench fever among homeless people in marseilles, france, we attempted isolation of bartonella quintana from body lice. a decontamination protocol of immersion in 70% ethanol with 0.2% iodine was devised and was tested with a laboratory colony of body lice. lice which had been experimentally contaminated with either escherichia coli, staphylococcus epidermidis, or acinetobacter spp. were successfully decontaminated, and this process did not prevent the culture of b. quint ... | 2001 | 11325978 |
| [endocarditis by bartonella in a patient with human immunodeficiency virus infection]. | 2001 | 11333726 | |
| quantitative analysis of valvular lesions during bartonella endocarditis. | cardiac valve pathology was evaluated in 15 patients with confirmed diagnosis of bartonella endocarditis. ten were infected by bartonella quintana and 5 by bartonella henselae. histologic features of these cases, including fibrosis, calcification, vegetation, pattern of inflammation, and vascularization, were compared with those of valves from 25 cases of non-bartonella endocarditis as controls using a computerized quantitative image analysis. pathologic and immunohistologic testing for localiza ... | 2000 | 11338477 |
| [pseudotumoral presentation of cat scratch disease]. | a frequent cause of chronic benign lymphadenopathy, cat-scratch disease (csd) occurs mainly in children and young adults. bartonella henselae is the agent responsible for csd. the most common symptoms of the disease are regional lymphadenopathy and fever. atypical forms occur in about 10% of patients; among them, csd may initially present as a tumor. | 2001 | 11339132 |
| invasion and persistent intracellular colonization of erythrocytes. a unique parasitic strategy of the emerging pathogen bartonella. | the expanding genus bartonella includes zoonotic and human-specific pathogens that can cause a wide range of clinical manifestations. a productive infection allowing bacterial transmission by blood-sucking arthropods is marked by an intraerythrocytic bacteremia that occurs exclusively in specific human or animal reservoir hosts. incidental human infection by animal-adapted bartonellae can cause disease without evidence for erythrocyte parasitism. a better understanding of the intraerythrocytic l ... | 2001 | 11342592 |
| longitudinal monitoring of the dynamics of infections due to bartonella species in uk woodland rodents. | blood samples were repeatedly collected from 12 sympatric woodland rodents over a 12-month period and dna extracts from each were incorporated into a bartonella-specific pcr targeting a fragment of the 16s/23s rrna intergenic spacer region (isr). the composition of each amplicon was analysed using restriction enzyme analysis (rea) and base sequence comparison. bartonella dna was detected in 70 of 109 samples. eleven samples contained dna derived from more than one strain. sequence analysis of 62 ... | 2001 | 11349984 |
| bartonella-associated infections in hiv-infected patients. | two species of the gram-negative bacilli bartonella, b. henselae and b. quintana, cause disease in hiv-infected patients. if untreated, infection can be fatal. manifestations include bacillary angiomatosis (ba), bacillary peliosis hepatis (bp), bacteremia, or a combination of these. ba and bp present as lesions, but bacteremia may be subacute and persist for months without diagnosis. additionally, patients may acquire cat scratch disease (csd), but this is more common in immunocompetent patients ... | 1995 | 11362939 |
| beware what you eat and drink, even while on haart. | people infected with hiv who are treated with highly active antiretroviral therapy (haart) are staying healthier for longer than ever before, but they still need to be cautious of exposure to foodborne and waterborne bacteria. the centers for disease control and prevention (cdc) lists several pathogens which can be dangerous to persons with hiv/aids, including mycobacterium avium complex (mac) and cryptococcosis. people with hiv who are infected by these pathogens tend to suffer from more severe ... | 1999 | 11366423 |
| [bartonella henselae as the causative agent in cat-scratch disease: case report]. | in this article we reported typical clinical, primary skin lesion and regional lymphadenitis, and atypical, protracted fever and algic syndrome, characteristics of cat scratch disease (csd) in a 21-year-old man (a student) from zadar, croatia. laboratory parameters were in normal range. the histopathologic findings of affected lymph nodes included stellate caseating granulomas. by using ifa method a seroconversion of specific igg antibodies (neg/1:512) and rise of igm antibodies (1:160/ > 1:320) ... | 2001 | 11379192 |
| bartonella henselae bacteraemia in patients with cat scratch disease. | 2001 | 11388603 | |
| bartonella interactions with endothelial cells and erythrocytes. | bartonella species are emerging human pathogens responsible for a wide range of clinical manifestations, including carrion's disease, trench fever, cat-scratch disease, bacillary angiomatosis-peliosis, endocarditis and bacteraemia. during infection of their human or animal reservoir host(s), these arthropod-borne pathogens typically invade and persistently colonize mature erythrocytes. however, in both reservoir and incidentally infected hosts, endothelial cells are target cells for bartonellae. ... | 2001 | 11390243 |
| dna amplification for the diagnosis of cat-scratch disease in small-quantity clinical specimens. | diagnosis of cat-scratch disease (csd) by polymerase chain reaction (pcr) of lymph node fineneedle aspiration (fna) and primary lesion specimens can be difficult owing to the minute amount of available material. a pcr assay specifically suited to test these specimens was developed. first, small-quantity (10 microl) samples were prepared from 17 csd-positive and 16 csd-negative specimens, and dna extraction and amplification from these samples were compared using 3 methods. sensitivity and specif ... | 2001 | 11392888 |
| establishing a direct role for the bartonella bacilliformis invasion-associated locus b (ialb) protein in human erythrocyte parasitism. | the invasion-associated locus a and b genes (ialab) of bartonella bacilliformis were previously shown to confer an erythrocyte-invasive phenotype upon escherichia coli, indirectly implicating their role in virulence. we report the first direct demonstration of a role for ialb as a virulence factor in b. bacilliformis. the presence of a secretory signal sequence and amino acid sequence similarity to two known outer membrane proteins involved in virulence suggested that ialb was an outer membrane ... | 2001 | 11401976 |
| [bartonella bacterium is suspected as the cause of sudden death among swedish cross-country runners]. | 2001 | 11402978 | |
| excessive tumor-elaborated vegf and its neutralization define a lethal paraneoplastic syndrome. | vascular endothelial growth factor (vegf) is a potent endothelial cell mitogen and key regulator of both physiologic and pathologic (e.g., tumor) angiogenesis. in the course of studies designed to assess the ability of constitutive vegf to block tumor regression in an inducible ras melanoma model, mice implanted with vegf-expressing tumors sustained high morbidity and mortality that were out of proportion to the tumor burden. documented elevated serum levels of vegf were associated with a lethal ... | 2001 | 11404464 |
| macular star in neuroretinitis. | 2001 | 11405817 | |
| molecular phylogeny of the genus bartonella: what is the current knowledge? | species of the genus bartonella are involved in an increasing variety of human diseases. in addition to the 14 currently recognized species, several bartonella strains have been recovered from a wide range of wild and domestic mammals in europe and america. such a high diversity of geographic distributions, animal reservoirs, arthropod vectors and pathogenic properties makes clarification of our knowledge about the phylogeny of bartonella species necessary. phylogenetic data have been inferred m ... | 2001 | 11410341 |
| cutting edge: antibody-mediated cessation of hemotropic infection by the intraerythrocytic mouse pathogen bartonella grahamii. | the genus bartonella includes important human-specific and zoonotic pathogens which cause intraerythrocytic bacteremia in their mammalian reservoir host(s). it is accepted that cellular immunity plays a decisive role in the host's defense against most intracellular bacteria. bartonella sp. infection in the immunocompetent host typically leads to immunity against homologous challenge. the basis of this immunity, be it cellular or humoral, is unclear. in this study, the course of bartonella graham ... | 2001 | 11418625 |
| pars plana vitrectomy for epiretinal membrane secondary to cat scratch neuroretinitis. | 2001 | 11421023 | |
| focal retinal phlebitis as a presenting sign of systemic bartonella henselae infection. | 2001 | 11421028 | |
| [serological cross-reaction among bartonella henselae, chlamydia pneumoniae and coxiella burnetii by indirect fluorescence antibody method]. | we studied the serological cross-reactions among bartonella henselae, chlamydia pneumoniae and coxiella burnetii by indirect fluorescence antibody (ifa) method, using sera from 8 patients with cat scratch disease (csd), 13 patients with c. pneumoniae infection and 12 patients with acute q fever. b. henselae igg antibody was negative in 13 patients with c. pneumoniae infection, and was positive in 3 (titers being 1:64) of 12 patients with q fever, whereas b. henselae igm antibody was negative in ... | 2001 | 11424490 |
| production of bartonella genus-specific monoclonal antibodies. | monoclonal antibodies (mabs) which react with heat-resistant proteins with molecular masses of 32 to 33 kda of 14 different bartonella species were produced. these antibodies did not react with antigens of 26 diverse bacterial strains by microimmunofluorescence assay except mab b3d4, which reacted with chlamydia psittaci and chlamydia trachomatis at low titers. the identification of a common bartonella antigenic protein will make it possible to later produce a diagnostic antigen by cloning and e ... | 2001 | 11427441 |
| [bartonellosis]. | 2001 | 11427808 | |
| [the worldwide challenges of "new" or reemerging communicable diseases at the dawn of the 21st century]. | in spite of the very significant advances made during the 20 th century in the prevention and the treatment of communicable diseases, infections are still today, even in developed countries, a major cause of morbidity and mortality. new infectious diseases have emerged (aids, legionellosis, exterotoxigenic e. coli, ebola fever), others have significantly reemerged (tuberculosis, diphtheria, bartonella infections) or have seen their geographic distribution widen considerably (dengue, hantavirus, ... | 2001 | 11427818 |
| bartonella hensela in inflammatory bowel disease. | 2001 | 11430386 | |
| [cat scratch disease. clinical study of 26 patients. role and importance of pcr]. | cat scratch disease is a mild pathology but diagnosis often remain difficult. | 2001 | 11433560 |
| cat-scratch disease: epidemiology, aetiology and treatment. | cat-scratch disease (csd) is a clinical syndrome that usually presents as a self-limiting lymphadenopathy associated with a cat scratch or bite. commonly affecting children and young adults, it has a worldwide distribution. in temperate climates, higher rates are reported in the autumn and winter, which can be attributed to the seasonal breeding of the domestic cat. the organism responsible was identified in 1983, having eluded detection for 50 years. initially, afipia felis was thought to be th ... | 2001 | 11440202 |
| bartonella henselae induces nf-kappab-dependent upregulation of adhesion molecules in cultured human endothelial cells: possible role of outer membrane proteins as pathogenic factors. | the endothelium is a specific target for bartonella henselae, and endothelial cell infection represents an important step in the pathogenesis of cat scratch disease and bacillary angiomatosis. mechanisms of bartonella-endothelial cell interaction as well as signaling pathways involved in target cell activation were analyzed. b. henselae strain berlin-1, isolated from bacillary angiomatosis lesions of a human immunodeficiency virus-infected patient, potently stimulated human umbilical cord vein e ... | 2001 | 11447190 |
| serological and epidemiological analysis of the prevalence of bartonella spp. antibodies in swedish elite orienteers 1992-93. | the emergence of the popular, physically demanding and highly nature-interactive sport of orienteering was marked in sweden by an elevated rate of sudden unexpected cardiac deaths in young competitors during the years 1979-92, with a common underlying cause or causes suspected. subsequently, sera were collected during 1992-93 from the elite segment of orienteers holding a nationally ranked position, and a survey compiling various epidemiological data was performed. in this study, a total of 1136 ... | 2001 | 11450861 |
| subacute bartonella infection in swedish orienteers succumbing to sudden unexpected cardiac death or having malignant arrhythmias. | during the period 1979-92, an increasing number of sudden unexpected cardiac deaths (sucd) occurred in young, swedish, male elite orienteers. myocarditis was the most common diagnosis in the 16 victims, and in 4 cases was also associated with fatty infiltration mimicking arrhythmogenic right ventricular cardiomyopathy (arvc). tissues from autopsies of 5 orienteers were tested for bartonella by pcr targeting the glta (citrate-synthase) gene. the products were then sequenced. antibodies to b. hens ... | 2001 | 11450862 |
| [bartonella henselae meningoencephalitis]. | 2001 | 11458191 | |
| an epitrochlear tumour. | 2001 | 11461986 | |
| epidemiologic and clinical characteristics of bartonella quintana and bartonella henselae endocarditis: a study of 48 patients. | 2001 | 11470985 | |
| 16s/23s rrna intergenic spacer regions for phylogenetic analysis, identification, and subtyping of bartonella species. | species of the genus bartonella are currently recognized in growing numbers and are involved in an increasing variety of human diseases, mainly trench fever, carrion's disease, bacillary angiomatosis, endocarditis, cat scratch disease, neuroretinitis, and asymptomatic bacteremia. such a wide spectrum of infections makes it necessary to develop species and strain identification tools in order to perform phylogenetic and epidemiological studies. the 16s/23s rrna intergenic spacer region (its) was ... | 2001 | 11473990 |
| immunofluorescent detection of intraerythrocytic bartonella henselae in naturally infected cats. | to determine the presence of bartonella henselae bacteremia in six cats, we compared isolation using blood culture with direct immunofluorescence on blood smears. three cats that were positive by blood culture were also positive by direct immunofluorescence, and laser confocal microscopy confirmed the intraerythrocytic location of b. henselae. | 2001 | 11474027 |
| serodiagnosis of cat scratch disease: response to bartonella henselae in children and a review of diagnostic methods. | in this study, sera from 116 children without clinical evidence of cat scratch disease (csd) and sera from 19 children with csd were investigated by two different immunofluorescent assays (test a and test b) to evaluate the seroprevalence of bartonella henselae antibodies in this population. antibodies against bartonella henselae were found in noninfected children only in low titers: 13% and 3.5% of serum samples were positive by test a and test b, respectively. igg titers as determined by test ... | 2001 | 11476439 |
| evaluation and use of a nested polymerase chain reaction assay in cats experimentally infected with bartonella henselae genotype i and bartonella henselae genotype ii. | cats have been shown to be infected with bartonella henselae genotype i, b. henselae genotype ii, and b. clarridgeiae. feline bartonellosis infections and the strains involved in these infections are important in both veterinary and human medicine. nucleic acid amplification methods such as polymerase chain reaction (pcr) are being used in both research and diagnostics as tools for understanding many infectious diseases. bartonella bacteremia in cats is detected by blood culture; however, becaus ... | 2001 | 11478603 |
| cat-scratch disease: considerations for dentistry. | cat-scratch disease, or csd, results from inoculation of the gram-negative bacillus bartonella henselae via a cat's scratch. a regional lymphadenitis, which usually is cervical, develops and may progress to suppuration. it is necessary to differentiate csd from other lymphadenopathies. | 2001 | 11480644 |
| differential detection of bartonella species and strains in cat scratch disease diagnostics by polymerase chain reaction amplification of 16s ribosomal rna gene. | cat scratch disease (csd) has been difficult to diagnose in animals because of the protracted clinical course of infection and the quiescent phases when the microbial culprit lies dormant. the causative agent in csd appears to be multiple species and strains of bartonella. using polymerase chain reaction (pcr) techniques for amplification of highly variable regions of the 16s ribosomal rna (rrna) gene sequence, a very sensitive species- and strain-specific assay for csd-causing bartonella specie ... | 2001 | 11482599 |
| ddt risk assessments. | 2001 | 11485878 | |
| acute endogenous endophthalmitis due to bartonella henselae. | a 45-year-old man presented with progressively worsening vitreitis of 1 week's duration. treatment for cat-scratch disease 3 years prior to presentation and persistent vitreitis led to vitrectomy, and analysis of the vitrectomy specimen revealed inflammatory cells and necrotic debris; polymerase-chain-reaction analysis of the vitreous fluid sample, done by use of a novel heminested protocol, demonstrated the presence of bartonella henselae dna. treatment with doxycycline led to improvement in th ... | 2001 | 11486295 |
| bartonella schoenbuchii sp. nov., isolated from the blood of wild roe deer. | the genus bartonella comprises two human-specific pathogens and a growing number of zoonotic or animal-specific species. domesticated as well as wild mammals can serve as reservoir hosts for the zoonotic agents and transmission to humans may occur by blood sucking arthropods or by direct blood to blood contact. humans may come into intimate contact with free-ranging mammals during hunting, especially during evisceration with bare hands, when accidental blood to blood contact frequently occurs. t ... | 2001 | 11491358 |
| [an adult case of systemic cat-scratch disease with hepatosplenic involvement]. | a previously healthy 25-year-old female was admitted to our hospital in november, 1997, for treatment of a spike-fever of 2 weeks' duration. she had a cat in her house but reported no history of cat bites or scratches. no peripheral lymphadenopathy was detected. white blood cell count was within normal limits, but an increased c-reactive protein level of 11.4 mg/dl was noted. infectious disease was suspected but ruled out as blood cultures were negative. empiric therapy with clarithromyoin, ison ... | 2001 | 11494569 |
| [bartonella henselae endocarditis. report of a case and review of the literature]. | bartonella spp are small gram-negative rods, aerobic and highly fastidious. they are difficult to culture, in the routine bacterial cultures. they are considered as emergent human pathogens. since 1993, three species of bartonella (b. quintana, b. henselae, and b. elizabethae) have been described as causative agents of infectious endocarditis. in this paper we describe the case of a 43 year-old woman with a previous valvular heart disease, probably of rheumatic origin, owner of cats, that suffer ... | 2001 | 11496560 |
| kinetics of bartonella birtlesii infection in experimentally infected mice and pathogenic effect on reproductive functions. | the kinetics of infection and the pathogenic effects on the reproductive function of laboratory mice infected with bartonella birtlesii recovered from an apodemus species are described. b. birtlesii infection, as determined by bacteremia, occurred in balb/c mice inoculated intravenously. inoculation with a low-dose inoculum (1.5 x 10(3) cfu) induced bacteremia in only 75% of the mice compared to all of the mice inoculated with higher doses (> or =1.5 x 10(4)). mice became bacteremic for at least ... | 2001 | 11500400 |
| bartonellosis (carrión's disease) in the modern era. | bartonellosis remains a major problem in peru, but many contemporary aspects of this disease have not been adequately described. we examined the cases of 145 symptomatic patients in lima, peru, in whom bartonellosis was diagnosed from 1969 through 1992, including 68 patients in the acute (hematic) phase and 77 patients in the eruptive (verruga) phase. in modern peru, symptomatic patients who have acute-phase bartonellosis typically present with a febrile illness and systemic symptoms caused by p ... | 2001 | 11512081 |
| probable atypical cat scratch disease presenting as isolated posterior pancreatic duodenal lymphadenitis and abdominal pain. | we report a case involving a 15-year-old girl with atypical, clinically unsuspected cat scratch disease (csd) presenting as isolated posterior pancreatic duodenal lymphadenitis, fever, and abdominal pain. the serological, abdominal ultrasonographic, and ct findings, as well as clinical and epidemiological data, indicate that b. henselae was likely an etiologic agent of csd in our patient. | 2001 | 11512100 |
| circulating cytokines in patients with cat scratch disease. | levels of circulating interleukin (il)-2, il-6, and il-10, measured by enzyme-linked immunosorbent assay, were significantly higher in patients with cat scratch disease (csd) than in healthy control subjects; no induction of il-12 was observed, and levels of interferon-gamma and il-4 were generally not detectable. this is the first report showing increased circulating cytokine levels in patients with csd. the induction of these mediators can partly explain some clinical and pathological features ... | 2001 | 11512109 |
| [cat scratch disease showing clinical picture resembling tuberculous lymphadenitis: a case report]. | on february 18th, 1997, a 61-year-old woman visited our hospital because of a left inguinal mass. on physical examination, the mass was soft without inflammatory sign. about one month later, the node was excised. pathological examination revealed granulomas with caseous necrosis and langhans giant cells, suggesting tuberculosis, although acid fast stain was negative. thereafter, re-history taking in detail disclosed that a kitten had often scratched her. we reexamined the pathology and checked h ... | 2001 | 11517562 |
| seroepidemiology of bartonella vinsonii subsp berkhoffii exposure among healthy dogs. | to determine seroprevalence of antibodies to bartonella vinsonii subsp berkhoffii and risk factors for seropositivity among working dogs owned by the us government. | 2001 | 11518174 |
| [longitudinal study of serological response to bartonella henselae by indirect fluorescence assay in cat scratch disease]. | sequential serologic testing for igg and igm titers to bartonella henselae were evaluated by an indirect fluorescence assay (ifa) in patients with csd. the ifa test for the detection of igg and igm antibodies to b. henselae in 52 csd patients showed that 40 (76.9%) were positive for igg antibody and 9 (17.3%) were positive for igm antibody. two or more consecutive serum samples from 30 patients with csd were assessed. in regard to the detection of igg antibody, 5 patients had rapidly elevated ti ... | 2001 | 11521278 |
| bartonella henselae serostatus is not correlated with neurocognitive decline in hiv infection. | bartonella henselae has been implicated as a significant cause of hiv-associated dementia. we attempted to confirm this association by utilizing the database of the san diego hiv neurobehavioral research center, which collects longitudinal neurocognitive and laboratory data on over 500 hiv-infected participants. utilizing an immunofluorescent assay we found that 11% of 177 subjects, half of whom had documented neurocognitive decline, were seropositive for b. henselae. there was no correlation be ... | 2001 | 11525353 |
| unsuspected extralymphocutaneous dissemination in febrile cat scratch disease. | cat scratch disease (csd) commonly manifests as regional self-limited lymphadenitis. however, dissemination of the infection to distant multiple sites may occur even in immunocompetent patients. we report a series of 11 children with fever and extralymphocutaneous manifestations of csd, in order to highlight potential multiorgan involvement in patients with febrile csd. to be eligible for enrollment, patients had to present with involvement of sites other than regional lymph nodes. the diagnosis ... | 2001 | 11525355 |
| native valve endocarditis due to bartonella henselae in a middle-aged human immunodeficiency virus-negative woman. | we report the case of a human immunodeficiency virus-negative woman who developed native valve endocarditis of the aortic valve due to bartonell henselae infection. the diagnosis was established using serology and pcr analysis of excised aortic valve tissue. | 2001 | 11526194 |
| seroprevalence of antibodies to microorganisms known to cause arterial and myocardial damage in patients with or without coronary stenosis. | infections are assumed to play a role in coronary artery disease (cad) and cardiomyopathies. it is unknown whether the seroprevalence of antibodies to these microorganisms is higher in patients with than without cad. the seroprevalence of antibodies to bartonella henselae, borrelia burgdorferi, chlamydia pneumoniae, coxiella burnetii, helicobacter pylori, human granulocytic ehrlichia, leptospira, rickettsia conorii, and treponema pallidum was assessed prospectively in patients with exertional dy ... | 2001 | 11527817 |
| bartonella henselae neuroretinitis. | 2001 | 11531989 | |
| identification, characterization, and functional analysis of a gene encoding the ferric uptake regulation protein in bartonella species. | environmental iron concentrations coordinately regulate transcription of genes involved in iron acquisition and virulence via the ferric uptake regulation (fur) system. we identified and sequenced the fur gene and flanking regions of three bartonella species. the most notable difference between bartonella fur and other fur proteins was a substantially higher predicted isoelectric point. no promoter activity or fur autoregulation was detected using a gfp reporter gene fused to the 204 nucleotides ... | 2001 | 11544240 |
| [taxonomy and classification of rickettsiae]. | during the recent 20 years the improvement of the methodological research basis including the molecular and genetic analysis of microorganisms parasites of eukaryotic cells, led to considerable changes in the taxonomy and classification of rickettsiae. this problem was not discussed in the russian literature. at present the term "rickettsiae" conventionally embraces the group of microorganisms of the class proteobacteria, nominated as species belonging to the genera rickettsia, orientia, ehrlich ... | 2001 | 11548242 |
| [hepatosplenic cat-scratch disease in the immunocompetent adult]. | atypical manifestations of cat-scratch disease have been described in children and immunosuppressed adults. we report the first case of hepatosplenic cat-scratch disease in an immunocompetent subject, demonstration of diversity of this infection. a 33-year-old man presented with prolonged fever, lymphadenopathy and multiple hypodense lesions of liver and spleen in ultrasonographic imaging. the hepatic biopsy showed non-specific inflammatory reactions including granulomata and stellate necrosis. ... | 2001 | 11552311 |
| evidence of a leading role for vegf in bartonella henselae-induced endothelial cell proliferations. | bartonella henselae causes the vasculoproliferative disorders bacillary angiomatosis (ba) and bacillary peliosis (bp). the pathomechanisms of these tumorous proliferations are unknown. our results suggest a novel bacterial two-step pathogenicity strategy, in which the pathogen triggers growth factor production for subsequent proliferation of its own host cells. in fact, b. henselae induces host cell production of the angiogenic factor vascular endothelial growth factor (vegf), leading to prolife ... | 2001 | 11553014 |
| interaction of bartonella henselae with the murine macrophage cell line j774: infection and proinflammatory response. | bartonella henselae is the causative agent of cat scratch disease (csd), a self-limiting condition characterized by a subacute regional lymphadenopathy that may develop into disseminated bartonellosis in immunocompromised subjects. mice experimentally infected with b. henselae display typical liver and spleen granulomas rich in t cells and macrophages. so far there are no data on the interaction between bartonellae and macrophages. in order to clarify this topic, we investigated the interaction ... | 2001 | 11553533 |
| bartonella henselae-specific cell-mediated immune responses display a predominantly th1 phenotype in experimentally infected c57bl/6 mice. | immune responses of the immunocompetent host to bartonella henselae infection were investigated in the murine infection model using c57bl/6 mice. following intraperitoneal infection with human-derived b. henselae strain berlin-1, viable bacteria could be recovered from livers and spleens during the first week postinfection, while bartonella dna remained detectable by pcr in the liver for up to 12 weeks after infection. granulomatous lesions developed in livers of infected mice, reached maximal d ... | 2001 | 11553587 |
| intracellular induction of the bartonella henselae virb operon by human endothelial cells. | one of the more recently identified bacterial exportation systems is the type iv secretion mechanism, which is characterized by a multiprotein complex that spans the inner and outer bacterial membranes and contains a pilin component. the most thoroughly studied type iv secretion system is encoded by the virb operon of agrobacterium tumefaciens. in bartonella henselae, 8 of the 10 virb operon genes share extensive homology and arrangement with the virb operon of a. tumefaciens. sequencing of the ... | 2001 | 11553594 |
| of fleas and ticks on cats and mice... | 2001 | 11559304 | |
| concurrent infection of the central nervous system by borrelia burgdorferi and bartonella henselae: evidence for a novel tick-borne disease complex. | to investigate bartonella henselae as a potential human tick-borne pathogen and to evaluate its role as a coinfecting agent of the central nervous system in the presence of neuroborreliosis. | 2001 | 11559306 |
| whipple's endocarditis: review of the literature and comparisons with q fever, bartonella infection, and blood culture-positive endocarditis. | whipple's disease is a systemic infection sometimes associated with cardiac manifestations. recently, there has been an increase in the number of reported cases of whipple's endocarditis. the purpose of our study was to describe this entity. data from 35 well-described cases of whipple's endocarditis were collected and compared with those of blood culture-positive endocarditis, q fever endocarditis, and bartonella endocarditis. some patients with generalized whipple's disease presented with card ... | 2001 | 11565070 |
| aortic valve endocarditis in a dog due to bartonella clarridgeiae. | we report the first documented case of endocarditis associated with bartonella clarridgeiae in any species. b. clarridgeiae was identified as a possible etiological agent of human cat scratch disease. infective vegetative valvular aortic endocarditis was diagnosed in a 2.5-year-old male neutered boxer. historically, the dog had been diagnosed with a systolic murmur at 16 months of age and underwent balloon valvuloplasty for severe valvular aortic stenosis. six months later, the dog was brought t ... | 2001 | 11574571 |
| pcr and sequencing of independent genetic targets for the diagnosis of culture negative bacterial endocarditis. | molecular methods utilizing broad-range primers for 16s rdna pcr and sequencing have been widely evaluated for their utility in culture negative diagnostic bacteriology. difficulties in determining the incidence of false positive pcr results, especially in the absence of an equally sensitive confirmatory method however, have prevented wide clinical use of this sensitive technology. here we report two cases of culture-negative endocarditis, in which pcr using 16s rdna broad-range primers generate ... | 2001 | 11576785 |
| [splenic abscess and cat-scratch disease]. | cat-scratch disease is caused by a gram-negative bacillus known as bartonella henselae. this disease is usually benign and causes regional adenitis that does not require treatment. however, some patients develop more serious atypical forms of the disease including prolonged systemic illness with hepatic and splenic abscesses.a 14-year-old girl was admitted to hospital with a 12-day history of persistent high fever and abdominal pain. ultrasonography and computerized tomography of the abdomen rev ... | 2001 | 11578546 |
| bartonella henselae neuroretinitis in cat scratch disease. | 2001 | 11587306 | |
| cat-scratch disease neuroretinitis diagnosed by a polymerase chain reaction approach. | to assess the value of polymerase chain reaction in the diagnosis of cat-scratch disease neuroretinitis without conclusive serology. | 2001 | 11589885 |
| atypical presentations of cat scratch disease in the head and neck. | 2001 | 11593185 | |
| serologic and molecular evidence of coinfection with multiple vector-borne pathogens in dogs from thailand. | forty-nine dogs from thailand were evaluated for serologic evidence of exposure or polymerase chain reaction (pcr) evidence of infection with vectorborne pathogens, including ehrlichia sp. (ehrlichia canis, ehrlichia chaffeensis, ehrlichia equi, and ehrlichia risticii), bartonella vinsonii subsp. berkhoffi (bvb), spotted fever group (sfg) rickettsiae (rickettsia rickettsii), typhus group (tg) rickettsiae (rickettsia canada, rickettsia prowazekii, and rickettsia typhi), and babesia sp. (babesia c ... | 2001 | 11596732 |
| [infections caused by bartonella spp]. | 2001 | 11602390 | |
| [two patients with bartonella henselae infection from a dog]. | two patients were reported as having been infected with bartonella henselae after having contact with a dog. both of the patients owned a dog, but had no contact with cats. one patient was a 10-year-old boy who had experienced a fever of 38-39 degrees c for 11 days, as well as having bilateral cervical lymphadenopathy. the boy's serum igm antibodies to b. henselae were negative on the 6th and 16th day of his illness, whereas his igg value, using indirect fluorescence antibody (ifa) method, was f ... | 2001 | 11605190 |
| cat-scratch disease presenting as multifocal osteomyelitis with thoracic abscess. | the case of a 4-year-old girl who presented with fever and back pain after being scratched by a kitten is presented. the diagnosis of cat scratch disease osteomyelitis was made by the detection of bartonella henselae dna by pcr analysis of a rib abscess aspirate. | 2001 | 11642619 |
| molecular diagnosis of infective endocarditis--a new duke's criterion. | the molecular approach of pcr amplification of specific gene targets and universal loci for bacteria (16s rrna) and fungi (18s, 28s and 5.8s rrna) and subsequent sequencing was used to identify the possible causal microbial agent(s) in blood culture (47 patients) and heart valve material (30 patients) from patients with suspected infective endocarditis (ie). culture and molecular results were analysed with respect to the patients' clinical background and the duke criteria. the findings demonstra ... | 2001 | 11669225 |
| possible role of high-dose corticosteroids in the treatment of cat-scratch disease encephalopathy. | approximately 2% of the estimated 24,000 patients in the united states who contract cat-scratch disease annually develop neurologic complications. between 1989 and 1999, 36 patients were admitted to our hospital with cat-scratch disease; 25% had neurologic complications, and the majority experienced lengthy hospital stays. we describe a case of cat-scratch disease encephalopathy in a 4-year-old girl who responded to high-dose corticosteroid therapy. further studies are warranted to determine if ... | 2001 | 11669351 |
| in vitro susceptibilities of bartonella and rickettsia spp. to fluoroquinolone antibiotics as determined by immunofluorescent antibody analysis of infected vero cell monolayers. | the in vitro susceptibilities of bartonella and rickettsia spp. to different concentrations of ciprofloxacin, levofloxacin, ofloxacin and sparfloxacin in vero cell cultures, were determined by enumeration of immunofluorescent-stained bacilli. after incubation in a co(2)-enriched atmosphere, inocula were replaced and tested with media containing 12 different concentrations of each antibiotic in replicate for each species and the monolayers were re-incubated. growth status was determined by evalua ... | 2001 | 11673033 |
| cat scratch disease. a cause of regional lymphadenitis. | in the last decade, the microbiological cause of cat scratch disease (csd) has been determined using a combination of traditional culture and modern molecular techniques. a bacterium known as bartonelia henselae is responsible for the vast majority of cases. the natural history of the disease is being reinterpreted in the light of more sophisticated diagnostic tools. | 2001 | 11681146 |