Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| comparison of a dna probe, complement-fixation and indirect immunofluorescence tests for diagnosing anaplasma marginale in suspected carrier cattle. | most estimates of the prevalence of anaplasmosis have been based on serologic data using the complement-fixation (cf) and/or card agglutination tests. since these tests are considered to be only about 50 percent reliable for detecting carrier cattle in enzootically stable herds, the need for more sensitive diagnostic tests is widely recognized. the objective in the present study was to compare the sensitivity of the cf test with that of the indirect immunofluorescence (iif) test and a recently d ... | 1990 | 2260275 |
| development of a recombinant anaplasma marginale dna probe. | an anaplasma marginale dna probe has been developed by using an improved method for the isolation of genomic dna. purified genomic a. marginale dna from the st. croix isolate was partially digested with sau 3a1 into fragments (greater than or equal to 5.0 kb). the restriction fragments were cloned using standard techniques in the pbr322 vector and used to transform e. coli (dh5) host cells. the recombinant a. marginale dna library was screened by the colony lifting procedure. colonies containing ... | 1990 | 2260276 |
| polyamines in human gastrointestinal malignancies. | this study was designed to investigate the clinical relevance of polyamine determination in human tissue, serum, and urine as diagnostic markers in the diagnosis or postoperative control of patients with gastrointestinal cancer. total, free, and acetylated polyamines were measured simultaneously in tissue, serum, and urine of patients with esophageal (n = 16), gastric (n = 40), pancreatic (n = 20) or colorectal (n = 50) carcinoma, in 40 patients with non-malignant gastrointestinal diseases, and ... | 1990 | 2262073 |
| nucleosome unit repeat size in aneuploid mice. | male 8-day-old mice that have part of chromosome 7 translocated to an x chromosome [t(x;7)1 ct] and that are chromosomally unbalanced for chromosome 7, and consequently trisomic for that part of chromosome 7, were found to have a smaller nucleosome repeat unit size than normal littermate males (rake, a. v., and edwards, r. h., biochem. genet. 25:671, 1987). this smaller nucleosome size is maintained in adult trisomic males. males with a balanced chromosomal translocation [t(x;7)1ct] had a normal ... | 2007 | 2268257 |
| ct scan and facial fractures. | 2007 | 2271061 | |
| ct scan and facial fractures. | 2007 | 2271061 | |
| intermediate site of development of anaplasma marginale in feeding adult dermacentor andersoni ticks that were infected as nymphs. | the development of anaplasma marginale in midgut epithelial cells was studied in feeding, transmitting adult dermacentor andersoni ticks. laboratory-reared ticks experimentally infected as nymphs were allowed to feed from 1 to 9 days on susceptible calves. gut tissues from ticks were collected on each day they fed (total, 9 days) and were processed for light and transmission electron microscopy. colonies of a marginale were abundant during the first 6 days of feeding, after which numbers decreas ... | 1990 | 2301812 |
| cyclic rickettsemia during persistent anaplasma marginale infection of cattle. | submicroscopic levels of anaplasma marginale rickettsemia in persistently infected cattle were determined by using nucleic acid hybridization. within individuals, the rickettsemia levels steadily increased from less than 10(4) infected erythrocytes per ml to a peak of more than 10(6) infected erythrocytes per ml and then rapidly declined. this logarithmic variation parallels the variation of the rickettsemia level seen in acute infection and suggests that cyclic emergence of antigenic variants i ... | 1990 | 2318532 |
| tick-borne diseases of cattle in paraguay. i. seroepidemiological studies on anaplasmosis and babesiosis. | a serological survey was carried out in paraguay to determine the prevalence of antibodies to anaplasma marginale, babesia bigemina and babesia bovis. the results suggest that the parasites are widely distributed throughout the country with prevalence rates of 92% for a. marginale, 79% for b. bigemina and 71% for b. bovis. epidemiological studies on calves demonstrated that initial infection with the three blood parasites occurs in most animals within the first nine months of life. it is likely ... | 1990 | 2321261 |
| simple method for stapled low colorectal or coloanal anastomosis. | a technique of stapled low colorectal or coloanal anastomosis is described, which follows eversion through the anus and stapled closure of the anorectal or anal remnant. the procedure is rapid and safe, and allows a secure distal clearance under direct visual control when dealing with tumors of the lower third of the rectum. | 2008 | 2323288 |
| plasma and urinary levels of carnitine in different experimental models of hyperammonemia and the effect of sodium benzoate treatment. | the effect of hyperammonemia on plasma and urinary levels of carnitine was studied in different groups of +/y (normal) and spf/y (chronically hyperammonemic) mice. experimental models of acute and subacute hyperammonemia were prepared in +/y and spf/y mice by the use of ammonium acetate ip injections and arginine-free diets, respectively. in acute hyperammonemia, the plasma levels of both free and acylcarnitines increased significantly whereas acyl/free carnitine ratio was decreased, indicating ... | 1990 | 2346672 |
| transient palsy of hip abductors after a fall on the buttocks. | a fall on the buttocks caused monolateral transient palsy of the hip abductors in two patients. palsy could be ascribed to acute entrapment of the superior gluteal nerve between the piriformis muscle and the incisura ischiadica major. | 2008 | 2346715 |
| characterization of a repetitive dna probe for babesia bigemina. | a plasmid (p16) containing a babesia bigemina dna insert was selected and labeled with 32p. this probe was evaluated for specificity and sensitivity by dot blot hybridization. the probe was specific and hybridized with only babesia bigemina dna, and not dna from babesia bovis, bovine leukocyte, trypanosoma brucei or anaplasma marginale. the dna probe detected as little as 10 pg of babesia bigemina dna. the probe hybridized with babesia bigemina isolates from mexico, the caribbean region and keny ... | 1990 | 2382379 |
| development and infectivity of anaplasma marginale in dermacentor andersoni nymphs. | the development of anaplasma marginale was studied in dermacentor andersoni nymphs after they had fed on a calf with ascending anaplasma infection. gut tissues were collected on day 4 of tick feeding, from newly replete (fed) nymphs and on postfeeding days (pfd) 5, 10, 15, 20, and were processed for light and electron microscopy to determine density of a marginale colonies. homogenates of gut tissues were prepared from nymphs collected on the same days and inoculated into susceptible, splenectom ... | 1990 | 2386330 |
| poor blood glucose regulation predicts sleep and memory deficits in normal aged rats. | poor glucose regulation predicts memory deficits in individual elderly humans. the present experiment determined whether glucose regulation was also related to memory and to sleep in aged rodents. glucose regulation, inhibitory avoidance, and daytime sleep were assessed in young (3-month-old) and old (24-month-old) rats. correlations were obtained between glucose regulation and the other variables in individual rats. in old rats, the magnitude of increases in blood glucose levels after glucose i ... | 1990 | 2394910 |
| synthesis and biological activity of guanylhydrazones of 2- and 4-pyridine and 4-quinoline carboxaldehydes. | a series of guanylhydrazones derived from 2- and 4-pyridine and 4-quinoline carboxyaldehydes was synthesized from s-methylisothio-semicarbazide hydroiodide using known procedures. the compounds are analogous to anticancer and antiviral thiosemicarbazones, but several of the guanylhydrazones derived from 4-quinoline carboxaldehyde showed no activity against p388 lymphocytic leukemia in mice. guanylhydrazones derived from all three heterocyclic aldehydes revealed significant blood pressure lowerin ... | 1990 | 2395098 |
| [interaction of local anesthetics with secretory cells at the membrane level]. | 1985 | 2408715 | |
| presence of common antigens, including major surface protein epitopes, between the cattle (intraerythrocytic) and tick stages of anaplasma marginale. | epitopes of major surface proteins of the intraerythrocytic cattle stage of anaplasma marginale were demonstrated in the midgut stage of the organism within the infective tick host dermacentor andersoni. these proteins were common to all a. marginale isolates tested and at all stages of parasitemia. sera from cattle immunized with the tick midgut stage of a. marginale immunoprecipitated multiple-erythrocyte-stage proteins, as demonstrated by sodium dodecyl sulfate-polyacrylamide gel electrophore ... | 1985 | 2415457 |
| genetic analysis of human b cell hybridomas expressing a cross-reactive idiotype. | we have examined the genetic basis for the expression of a human cross-reactive idiotype (cri) commonly found on monoclonal igm rheumatoid factors. the cri was identified with a monoclonal antibody (17.109) and has been localized previously to the kappa-variable region. by using the human lymphoblastoid cell line wi-l2-729-hf2, and mononuclear cells from several sources, a panel of hybridomas was generated that produced 17.109 cri-positive ig. a recently cloned human germ-line v kappa iii gene, ... | 1987 | 2433336 |
| influence of gangliosides on primary and metastatic neoplastic growth in human and murine cells. | the influence of gangliosides on tumor growth and frequency of metastasis in vivo as well as on growth and motility of neoplastic cells in vitro was tested utilizing human and rodent cell populations. in mice receiving injections of a ganglioside mixture twice daily the tumor volume, the number of spontaneous metastases per animal, and the number of mice with metastasis was approximately double that of controls. preincubation of neoplastic cells with the ganglioside mixture doubled the number of ... | 1987 | 2440560 |
| characterization of an immunoprotective protein complex of anaplasma marginale by cloning and expression of the gene coding for polypeptide am105l. | immunization with an anaplasma marginale surface protein complex containing two polypeptides (am105u and am105l), each having a molecular weight of 105,000, protected cattle against challenge with virulent organisms. these polypeptides were immunoprecipitated together from detergent extracts of a. marginale by a neutralizing monoclonal antibody. after surface radioiodination of intact parasites, both am105u and am105l contained the radiolabel. to define the structural and antigenic relationships ... | 1987 | 2443451 |
| [anti-p2 protein antibodies in patients with polyradiculoneuropathy]. | 2008 | 2446811 | |
| epinephrine impairs insulin release by a mechanism distal to calcium mobilization. similarity to lipoxygenase inhibitors. | the mechanisms that enable epinephrine (epi) and lipoxygenase inhibitors to impede insulin secretion are unknown. we examined the possibility that epi inhibits ca2+ fluxes as its major mechanism by studying 45ca efflux from prelabeled, intact rat islets. epi (2.5 x 10(-7) to 1 x 10(-5) m) inhibited insulin release induced by the influx of extracellular ca2+ (46 mm k+) or the mobilization of intracellular ca2+ stores (2 mm ba2+), but it did not reduce the 45ca efflux stimulated by either agonist. ... | 1988 | 2446939 |
| characterization of a neutralization-sensitive epitope on the am 105 surface protein of anaplasma marginale. | 1987 | 2448258 | |
| differential extraction of antigens of anaplasma marginale. | strain-, group-, and genus-specific antigens of the florida isolate of anaplasma marginale had different solubilities in zwitterionic, nonionic, and anionic detergents. on the basis of their solubility in nonionic detergent, antigens were grouped into 3 classes: (i) a 108-kilodalton (kd) group-specific antigen and a series of poorly defined antigens (70 to 100 kd) were completely soluble in nonionic detergent; (ii) 96 kd and 75 kd group-specific antigens, and a 91-kd strain-specific antigen were ... | 1988 | 2450497 |
| nucleic acid levels in anaplasma marginale during experimentally induced bovine anaplasmosis. | the dna and rna concentrations in uninfected and anaplasma marginale-infected bovine erythrocytes were determined. bovine anaplasmosis was experimentally induced and the nucleic acid levels were followed during the development of the a. marginale infection. two distinct growth stages were found, the "multiplication" stage and the "transfer" stage. based on this hypothetycal developmental cycle, the amount of dna and rna per anaplasma initial body was estimated as 73.1 x 10(-3) pg and 45.7 x 10(- ... | 1988 | 2451913 |
| recognition of conserved surface protein epitopes on anaplasma centrale and anaplasma marginale isolates from israel, kenya and the united states. | 1988 | 2452797 | |
| preliminary studies of the development of anaplasma marginale in salivary glands of adult, feeding dermacentor andersoni ticks. | on each day of feeding on susceptible calves, salivary glands obtained from groups of adult ticks that transmitted anaplasma marginale were examined for a marginale colonies by use of light microscopy and transmission electron microscopy. on day 8 of feeding, salivary glands were examined, using fluorescein-labeled antibody and methyl green-pyronine stain. use of fluorescein-labeled antibody consistently revealed small numbers of fluorescent foci in salivary gland acinar cells obtained from tick ... | 1988 | 2458688 |
| [ticks and hemoparasitoses of livestock in senegal. iii. the northern sudan area]. | the authors describe the results of a study on ticks and hemoparasitoses of cattle and small ruminants in the senegalese north-sudanian area. for 15 months, 40 bovine, 40 sheep and 40 goats received a routine dipping treatment, aimed at the determination of the tick population dynamics together with an accurate localization of the preferential sites for the different species. the following parasites were collected from the animals: hyalomma marginatum rufipes, h. truncatum, rhipicephalus lunulat ... | 1989 | 2485548 |
| [comparative study of the university of wisconsin solution versus eurocollins in kidney transplant]. | uw (university of wisconsin) solution, formulated by belzer's team in madison, has already been proved to increase cold ischemia time in liver and pancreas preservation. a multicentre clinical trial is being conducted to compare renal preservation in human transplantation using two different solutions: uw and eurocollins (ec). this paper, whose results will be included in the multicentre trial, reports local comparative results between uw and ec perfused kidneys. the two donor populations uw (28 ... | 1989 | 2486309 |
| institutional review boards. | 2008 | 2500193 | |
| [thoracic nodular lesions]. | 2008 | 2518936 | |
| [lactic acidosis in diabetic patients associated with buformin]. | 2008 | 2519422 | |
| dopamine d1 binding sites in the striatum of the mutant mouse weaver. | in the weaver mouse there is a major abnormality in the dopamine-containing innervation of the striatum. dopamine islands from during development, along with some innervation of the non-islandic matrix; but during the first postnatal month much of the islandic innervation degenerates and there is a failure of the normal postnatal development of the diffuse nigrostriatal innervation. in the experiments reported here we analysed the distribution of d1 dopamine receptor-related binding sites in the ... | 1989 | 2527338 |
| [a new 2-compartment catheter for controlled drainage of hepatic venous blood to the extracorporeal space]. | a new therapeutic catheter designated as "2-compartment-catheter by helzel" for on-target hepatic vein blood drainage to extracorporal space, without blocking the caval blood flow to the right atrium, is presented. its principle of action is outlined. first experiences in animals are reported. using 2 additional catheters, isolated liver perfusion by "pure catheter technique"--without laparotomy--is now possible for various therapeutic approaches. | 1989 | 2538888 |
| [effect of cyclic nucleotides (camp) on experimental hsv-i keratitis]. | the authors report an experimental study on the effect of camp on hsv-i keratitis. rabbit corneas developed typical dendritic keratitis on the 3rd day after inoculation of hsv-i. on the 9th day, the camp level in plasma significantly decreased from 174.9 +/- 20.2 to 52.1 +/- 18.2 pmol/ml, while the cgmp level increased. the camp level in aqueous humour also decreased, with an increase in cgmp level increased. the camp level in aqueous humour also decreased, with an increase in cgmp level. camp w ... | 1989 | 2551611 |
| first assisting in cataract surgery: program results. | 1. this program was established to teach non-physicians to first assist in cataract surgery, since third party payors would no longer pay for physicians to first assist. 2. among the advantages to utilizing non-physician first assistants are: availability, reliability, familiarity with instruments and equipment, and quality of service. 3. the questionnaire results confirm that the advantages of having non-physician first assistants far outweigh the disadvantages. | 2008 | 2566208 |
| different gamma-glutamyl transpeptidase mrnas are expressed in human liver and kidney. | in human, the two subunits of gamma-glutamyl transpeptidase (ggt) arise from a common precursor encoded by a multigene family. until now, a single specific coding sequence for this precursor (type i) has been identified in human placenta and liver. in the present study, we have isolated from a human kidney cdna library, a ggt specific clone (0.8 kb). the sequence of which (type ii) i) covers the carboxy terminal part of the ggt precursor, ii) exhibits 22 point mutations and a 30 bp deletion as c ... | 1989 | 2573352 |
| erythrocyte osmotic fragility and cation concentrations during experimentally induced bovine anaplasmosis. | 1. the osmotic fragility, the concentrations of na, k and ca, the osmolality and the total atpase activity of bovine erythrocytes from uninfected and anaplasma marginale-infected bovines were studied in an attempt to correlate these parameters with the decrease in the cellular atp concentration reported during bovine anaplasmosis. 2. the osmotic fragility found in infected bovine erythrocytes, at 0.52% nacl, was about two times greater than that observed in non-infected bovines. the increase in ... | 1989 | 2574096 |
| a simple intravenous infusion method in rodents for determining the potency of anticonvulsants acting through gabaergic mechanisms. | a simple method of intravenous infusion of convulsant drugs (pentetrazol and bicuculline) into the tail vein of rats has been used to determine seizure threshold and construct log-dose seizure threshold response curves for several anticonvulsant drugs (diazepam, phenobarbitone, pentobarbitone, chlormethiazole and valproate). it has been shown that an index of the dose required to increase seizure threshold by 50% (ti50) can be obtained using small numbers of animals. the advantages of this metho ... | 1989 | 2576457 |
| serotonin in fore-gut carcinoids. a survey of 60 cases with regard to silver stains, formalin-induced fluorescence and serotonin immunocytochemistry. | a series of 60 fore-gut carcinoid tumours was examined with regard to serotonin content after application of three different techniques, namely: the argentaffin reaction, formalin-induced fluorescence according to falck-hillarp and immunocytochemistry with monoclonal antibodies to serotonin. to evaluate the staining-fluorescence of individual tumour cells, the methods were applied to identical tumour sections. twelve tumours demonstrated serotonin-immunoreactive cells, six of which were also arg ... | 2008 | 2580071 |
| cloned dna probes identify anaplasma ovis in goats and reveal a high prevalence of infection. | anaplasma organisms are observed in erythrocytes from goats with anemia and weight loss in kenya. three anaplasmas have been isolated in nature, anaplasma ovis, anaplasma marginale, and anaplasma centrale. the two recognized species, a. ovis and a. marginale, are known to infect goats. since only a. ovis causes clinical disease in goats, the anaplasma species in goats in kenya were identified. to detect a. ovis, a 9.6-kilobase-pair section of genomic dna was cloned into pbr322 (pao12a) and was u ... | 1989 | 2592538 |
| infectivity and antigenicity of anaplasma marginale from tick cell culture. | the infectivity and immunogenicity of anaplasma marginale grown in a tick cell culture from embryonic dermacentor variabilis ticks were assessed in splenectomized and intact calves, respectively. culture 1 consisted of the cell line inoculated with midguts of adult ticks infected with the mississippi isolate of a marginale and dissected 5 to 10 days after repletion and detachment from an experimentally infected calf. cultures 2 and 3 consisted of the cell line inoculated with midguts of ticks in ... | 1989 | 2610428 |
| [drug-induced cardiovascular complications]. | many drugs, including those prescribed in cardiology, can induce adverse cardiovascular side effects. most of the anti-arrhythmia drugs have a negative inotropic action and proarrhythmic effects. estroprogestative contraceptive drugs favor thromboembolitic events and increase the incidence of hypertension. due to the risk of coronary insufficiency, substitutive hormonotherapy in hypothyroidism must be introduced gradually. tricyclic anti-depressive drugs and neuroleptics can induce orthostatic h ... | 2008 | 2610453 |
| [treatment of fractures of the distal quarter of the leg using ilizarov's method: preliminary results]. | the authors report their experience about the treatment of the fractures of the distal end of the leg, by means of the method of ilizarov. the type of apparatus used and the technique of assembling are presented. the authors point out the validity and advantage of this method, especially when compared to a.o. osteosynthesis. | 2008 | 2612265 |
| [treatment of fractures of the distal quarter of the leg using ilizarov's method: preliminary results]. | the authors report their experience about the treatment of the fractures of the distal end of the leg, by means of the method of ilizarov. the type of apparatus used and the technique of assembling are presented. the authors point out the validity and advantage of this method, especially when compared to a.o. osteosynthesis. | 2008 | 2612265 |
| the pattern of tuberculosis in addis ababa, ethiopia. | two hundred and forty available charts of medical patients treated for tuberculosis at tikur anbessa hospital in addis ababa, ethiopia over 2 years (9/83-9/85 were studied. tb was diagnosed in 11.2% of medical admissions. the average age of tb patients was 30.5; 58% were males; 53% were classed as poor. tb patients were poorer than other medical patients and averaged 38.9 days in hospital, non-tb patients averaged 31.9 days. pulmonary disease was most common (47% of total), followed by spondylit ... | 2008 | 2612412 |
| the pattern of tuberculosis in addis ababa, ethiopia. | two hundred and forty available charts of medical patients treated for tuberculosis at tikur anbessa hospital in addis ababa, ethiopia over 2 years (9/83-9/85 were studied. tb was diagnosed in 11.2% of medical admissions. the average age of tb patients was 30.5; 58% were males; 53% were classed as poor. tb patients were poorer than other medical patients and averaged 38.9 days in hospital, non-tb patients averaged 31.9 days. pulmonary disease was most common (47% of total), followed by spondylit ... | 2008 | 2612412 |
| new interventional technology for the management of multivessel coronary artery disease. | 2000 | 2627965 | |
| [significance of teaching social welfare in nursing training]. | 2009 | 2632889 | |
| occupational medicine. organizational behavior. | work flow and the administrative processes by which it is controlled are fundamental in shaping the realities of the organization as a system of relationships. organization is technology in the broadest sense: processes, procedures, policies, controls, formal authority structures, and techniques. among groups or organizations, it is unusual for changes in sentiment to precede action or organizational rearrangements. technology and structure must be changed first. this chapter has outlined organi ... | 2008 | 2644717 |
| successful implantation of penile prostheses in organ transplant patients. | we present our experience with implantation of penile prostheses in 6 organ transplant recipients, including 2 patients after renal transplantation and 4 patients after cardiac transplantation. we have seen no problems related to prosthesis surgery in this patient population, and in particular have experienced no infectious complications. all patients received strict perioperative antibiotic and steroid coverage. we conclude that erectile impotence in the male organ transplant patient can be suc ... | 2009 | 2648658 |
| delivered volume during high-frequency ventilation. | 1989 | 2648741 | |
| [current status of hyperthermia for deep-seated tumors]. | the current status of hyperthermia for deep-seated tumor is reviewed. heating methods include external heating, intraluminal heating and interstitial heating, all of which have inherent advantages and disadvantages. hyperthermia alone has significant effects on deep-seated tumors. the combination of hyperthermia and radiotherapy has been widely applied, resulting in 10-15% complete regression and 10-40% partial regression in the treatment of locally advanced tumors. the response rate of thermora ... | 2009 | 2649000 |
| hepatic and biliary tract abnormalities in patients with aids. sonographic-pathologic correlation. | a retrospective evaluation of hepatobiliary sonograms in 22 patients with aids was performed and the sonographic abnormalities were correlated with pathologic findings in 10 patients. hepatic parenchymal abnormalities noted on ultrasound include a hyperechoic parenchymal echo pattern in 45.5%, hepatomegaly in 41%, and focal masses in 9% of patients. etiologies for the diffuse hyperechoic pattern based on pathologic correlation in eight cases were hepatic steatosis and granulomatous hepatitis. bi ... | 1989 | 2654415 |
| neuroendocrinology of the thymus. | the neuropeptides oxytocin (ot) and vasopressin (vp) are synthesized in the human thymus in a similar way as in the hypothalamo-neurophypophyseal system. immunocytochemistry with polyclonal and monoclonal antibodies revealed that immunoreactive ot- and vp-producing cells are localized in the subcapsular cortex and medulla of human and murine thymuses. the epithelial nature of the neuroendocrine thymic cells is demonstrated by their immunostaining with a monoclonal antibody against cytokeratin. a ... | 1989 | 2656471 |
| [general problems of selection and interpretation of diagnostic methods]. | the author draws attention to general principles which must be respected in the selection and interpretation of diagnostic methods. he discusses the importance of basic characteristics of the diagnostic test (reliability, accuracy, sensitivity, specificity, predictive value) and their application in the examination process. he explains the importance of roc analysis in the selection of the optimal diagnostic method. he refers to the criteria which must be taken into account when introducing and ... | 2009 | 2663170 |
| major abdominal complications following cardiac transplantation. utah transplantation affiliated hospitals cardiac transplant program. | serious complications involving the alimentary tract are commonly reported following cardiac transplantation, and may be associated with significant morbidity and mortality. the aim of this report was to review the incidence, severity, and outcome of abdominal complications in our heart transplant population in whom we used corticosteroid-sparing protocols for immunosuppression. from march 1985 through september 1988, 178 patients underwent 185 cardiac transplants. twenty-six cardiac transplant ... | 2009 | 2667501 |
| an early twentieth-century skeleton collection. | the collecting of human remains for study in museums and medical schools has been a vital scientific endeavor for many years. in some cases, such as the fetal and neonatal skeletons discussed, surreptitious dealings were involved. however, one must consider the attitudes that prevailed at the time, the high rate of fetal and infant mortality, and the blossoming role of museums as repositories of knowledge. | 1989 | 2668444 |
| seroepidemiology of anaplasma marginale in white-tailed deer (odocoileus virginianus) from louisiana. | antibodies to anaplasma marginale were detected by the indirect fluorescent antibody test (ifa) in six of 331 (2%) serum samples of white-tailed deer (odocoileus virginianus) from louisiana. none of the serum samples were positive using the a. marginale modified rapid card agglutination test. of the six ifa positive sera retested by the complement fixation test four sera gave anticomplementary and two gave seropositive reactions. the low a. marginale reactor rate in this white-tailed deer popula ... | 1989 | 2668567 |
| seroprevalence of anaplasmosis in the red river plains and south-east areas of louisiana. | the indirect fluorescent antibody test was used to detect antibodies to anaplasma marginale in serum samples collected from cattle in the red river plains and south-east areas of louisiana. convenience sampling of herd clusters was used. a reactor rate of 7.8% was found in 11,085 samples. beef cattle had a 11.2% reactor rate compared with 3.8% for dairy cattle. the angus and angus cross-breed group had the highest reactor rate. | 1989 | 2675458 |
| cytochrome p-450 membrane signals. | 2009 | 2680408 | |
| interrelationships between digestive proteolytic activities and production and quantitation of toxins in pseudomembranous colitis induced by clostridium difficile in gnotobiotic mice. | clostridium difficile pathogenicity is related to in vivo production of toxins, and it is of great interest to detect toxins produced in biological samples. several reports have shown that proteases in stools interfere with immunological methods for quantitation of toxin a. the purpose of this work was to estimate the relationship between the proteases and the c. difficile toxins produced in a gnotobiotic mouse model of pseudomembranous cecitis. cecal proteolytic activities hydrolyzed toxin a, a ... | 1989 | 2680988 |
| clinical experience with ciprofloxacin: analysis of a multicenter study. | in a multicenter study of 36 patients treated with ciprofloxacin (mean daily dosage, 986 mg per day; mean duration of treatment, 10.8 days) for a variety of infections, 32 were microbiologically proven. of these, bacteriologic cure and/or improvement resulted in 100% of cases. for all 36 infections clinical cure and/or improvement resulted in 97.1% of cases. a total of 13 infections were classified as chronic. overall there were six adverse reactions reported in 4/36 (11.1%) patients. five were ... | 2009 | 2681482 |
| serum beta 2 microglobulin in ankylosing spondylitis. | 2009 | 2681760 | |
| rna editing at a splicing site of nadh dehydrogenase subunit iv gene transcript in wheat mitochondria. | comparison between the sequence of the gene coding for the wheat mitochondrial nadh dehydrogenase subunit iv (nad4) and the cdna sequence obtained by reverse transcription, using total wheat mtrna as template, has shown the presence of a uridine residue, not encoded by the genomic sequence, at the exon2-exon3 junction of the spliced transcript. this u creates a non-encoded cug leucine codon which is essential for maintaining the reading frame, as shown by the conservation of the amino acid seque ... | 2009 | 2687023 |
| cardiovascular, respiratory, and metabolic responses to upper body exercise. | many studies have suggested that arm exercise, particularly in the supine position or with arms elevated, is more stressful than leg exercise. arm exercise at a given workload is typified by cardiac output and oxygen consumption values slightly higher and heart rate, blood pressure, ventilatory and blood lactic acid responses that are significantly higher than those observed during leg exercise. part of the increased physiological stress during arm exercise may be due to sluggish kinetics of oxi ... | 2009 | 2691823 |
| [dr. miklós tímár on his 75th birthday]. | 2009 | 2691954 | |
| anaplasma marginale in tick cell culture. | anaplasma marginale was propagated in a tick cell line derived from dermacentor variabilis embryos. the rickettsial organism was identified and monitored in culture by transmission electron microscopy and the indirect immunofluorescence technique, using specific monoclonal antibodies. inoculation of the embryonic tick cell line with midguts of infected adult ticks (culture 1), nymphal ticks (culture 2) and adult ticks that were infected as nymphs and dissected as adults (culture 3) resulted in 3 ... | 1989 | 2692483 |
| sce induction by ccnu and pregnancy. | 2009 | 2704378 | |
| a stereophotogrammetric method for measurements of ligament structure. | a stereophotogrammetric method is presented to reconstruct the course of a curve in the three-dimensional space. this method is exclusively suitable as a non-destructive tool to determine the surface fiberstructure of ligaments, tendons and other organised collagenous structures. in addition, it is a convenient tool to measure the geometry of articular surfaces and other complicated surface shapes. | 2009 | 2708397 |
| brain biocompatibility of a biodegradable, controlled-release polymer in rats. | we report the biocompatibility in the rat brain of a controlled-release, biodegradable polymer, the polyanhydride poly-[bis(p-carboxyphenoxy)propane-sebacic acid] copolymer (pcpp-sa) in a 20:80 formulation. the biodegradable polyanhydride can be used for drug delivery directly into the brain, circumventing the difficulties posed by the blood-brain barrier and avoiding the consequences of having to administer toxic doses systematically to reach therapeutic doses in the central nervous system. the ... | 1989 | 2708412 |
| transvestites' women revisited: a nonpatient sample. | data obtained from seven female partners of nonpatient transvestites are presented. none were receiving psychiatric treatment. the group was self-assembled and affiliated with a cross-dressing social organization. the sample was divided into acceptors and rejectors based on the degree of acceptance of their mate's cross-dressing activities. mean relationship duration was 9.9 years. none were traumatized by accidental discovery of their mate's transvestism. childhood loss of parent(s), substance ... | 2009 | 2712686 |
| [an unusual slow course of systemic vasculitis with multiorgan involvement]. | this paper reports on an unusually slowly progressing course seen in systemic vasculitis of the median and smaller arteries and small veins associated with dermatomyositis, chronically active hepatitis, glomerulonephritis of the immune complex and restrictive cardiomyopathy in a 35-year-old patient. the authors discuss the difficulties in establishing the diagnosis and in finding the exact classification of this disease. | 2009 | 2714835 |
| levodopa/dopamine analogs as inhibitors of dna synthesis in human melanoma cells. | compounds possessing the ortho-dihydroxybenzene moiety and structurally related to levodopa and dopamine appear to belong to a new class of biologically active agents that are capable of inhibiting dna synthesis in a variety of normal and malignant eukaryotic cells. they appear to work in part through their properties as potent reducing agents, and thereby interfere with several redox reactions that are crucial to the synthesis of cellular dna. interestingly, the compounds can then be converted ... | 1989 | 2715667 |
| antagonism of central and peripheral anorectic effects of caerulein by l-364,718. | the reduction in food intake induced by i.p. injections of the cholecystokinin (cck) analogue caerulein was antagonised by a low dose (0.25 mumol/kg s.c.) of the selective cck antagonist l-364,718. to block the anorectic effect of centrally administered caerulein a dose of 25 mumol/kg of l-364,718 was required, demonstrating that central cck receptors can be blocked effectively in the rat by choosing appropriate doses of l-364,718. | 1989 | 2721558 |
| antagonism of central and peripheral anorectic effects of caerulein by l-364,718. | the reduction in food intake induced by i.p. injections of the cholecystokinin (cck) analogue caerulein was antagonised by a low dose (0.25 mumol/kg s.c.) of the selective cck antagonist l-364,718. to block the anorectic effect of centrally administered caerulein a dose of 25 mumol/kg of l-364,718 was required, demonstrating that central cck receptors can be blocked effectively in the rat by choosing appropriate doses of l-364,718. | 1989 | 2721558 |
| development of neural inducing capacity in dissociated xenopus embryos. | during gastrulation in amphibians, dorsal ectoderm is converted by induction from an epidermal pathway to central nervous system (cns). we show in this report that the ability of the embryo to manufacture this neural inducing signal is not dependent upon intercellular communication between early cleavage and early gastrula stages. this result is consistent with the interpretation that the cell lineage that induces cns formation arises itself by a cell-autonomous mechanism, perhaps specified by m ... | 2009 | 2731653 |
| amino acid sequences and disulfide bridges of serine proteinase inhibitors from bitter gourd (momordica charantia linn.) seeds. | three serine proteinase inhibitors, mcti-i, mcti-ii, and mcei-i, were isolated from bitter gourd (momordica charantia linn.) seeds. mcti-i and mcti-ii were inhibitors for trypsin and mcei-i was an elastase inhibitor. their amino acid sequences and the positions of disulfide bridges of mcti-ii were determined to be as follows. (sequence; see text) | 2009 | 2738047 |
| [effect of concomitant pathology and radiation treatment on the immunity indices of patients with laryngeal cancer]. | humoral and cell-mediated immunity in laryngeal cancer patients was evaluated versus presence of concomitant pathology and previous irradiation. the actual t-lymphocyte level in the study group was shown to exceed that measured by reaction of spontaneous rosette formation using sheep erythrocytes. concomitant pathology appeared to impair immune status. distant gamma irradiation suppressed cell-mediated immunity boosting the humoral one. in vitro incubation of peripheral blood lymphocytes with le ... | 1989 | 2741432 |
| [complexing of bovine serum albumin with phosphatidyl choline liposomes]. | thermodynamic parameters of the bovine serum albumin interaction with phosphatidyl choline liposomes have been determined. it is shown that the bovine serum albumin is adsorbed on the liposomal surface without change of the globule conformation, the polar interactions making dominant contribution in immobilization. the complexing is characterized by a binding constant and a great number of binding sites. | 1989 | 2749908 |
| distribution of a boronated porphyrin in murine tumors. | 2009 | 2751609 | |
| effect of hydergine in hyperprolactinemia. | the prl-inhibiting and ovulation-inducing effects of hydergine were studied in 18 patients with hyperprolactinemic ovulatory disturbances. the women were divided into 2 groups of 9 each. those in group a had basal serum prl levels higher than 100 micrograms/l, and those in group b had basal serum prl levels lower than 100 micrograms/l. serum prl levels in both groups were determined before and hourly for 8 h after a single oral dose of either 2 mg hydergine or placebo. hydergine induced a signif ... | 2009 | 2753986 |
| detection of babesia bigemina in cattle by a radioimmunoassay incorporating specifically depleted antigen. | it was observed that mild acidification (ph less than 4.0) together with solvent extraction of the soluble sonicate of a crude preparation of babesia bigemina infected cattle erythrocytes caused a quantitative loss of b. bigemina-specific antigen. cross-reacting antigen activities with babesia bovis remained intact. these properties were utilized in an assay system wherein antibody response to the specifically depleted antigen preparation was subtracted from the response to the initial crude pre ... | 1989 | 2763443 |
| enzymes of oxidant defence system of leucocytes and erythrocytes in bovine anaplasmosis. | the glutathione oxidant defence system in leucocytes and erythrocytes of six anaplasma marginale-infected calves was examined by assaying glutathione peroxidase (gsh-px), glutathione reductase (gssg-r), reduced glutathione (gsh) and superoxide dismutase (sod). in addition, gsh-s-transferase and arginase levels were measured in leucocytes. there was a significant decline in the activities of leucocyte gsh-px, gssg-r and sod in the post-patent period; whereas arginase activity rose significantly f ... | 1989 | 2763451 |
| effects of idebenone on memory impairment induced in ischemic and embolization models of cerebrovascular disturbance in rats. | two rat models of memory impairment in passive avoidance learning induced by cerebrovascular disturbance, were established to estimate the effects of a cerebral metabolic enhancer, idebenone. transient and global cerebral ischemia in rats, produced by 4-vessel occlusion for 200 s immediately after the acquisition trial of passive avoidance learning, shortened the latencies in the retention test trial performed 24 h later. this retrograde amnesia was reversed significantly by idebenone administer ... | 1989 | 2764639 |
| morning glory syndrome associated with marked persistent hyperplastic primary vitreous and lens colobomas. | a case of morning glory syndrome with striking persistence of primary vitreous is presented. the hypothesis that the syndrome is an expression of abnormal closure of the embryonic fissure is substantiated by the coexistence of lens colobomas. furthermore, the marked primary vitreous hyperplasia shows the way in which persistence of primary vitreous influences the clinical expression with respect to optic pit and colobomas of the optic nerve. | 2009 | 2765452 |
| taking charge: we wanted a smoke-free workplace and we got it. | 2009 | 2772525 | |
| sorbitol and dental plaque. aspects of caries-related microbiological and biochemical factors. | 1989 | 2772837 | |
| the contrasting structures of mismatched dna sequences containing looped-out bases (bulges) and multiple mismatches (bubbles). | we have studied the structure and reactivities of two kinds of mismatched dna sequences--unopposed bases, or bulges, and multiple mismatched pairs of bases. these were generated in a constant sequence environment, in relatively long dna fragments, using a technique based on heteroduplex formation between sequences cloned into single-stranded m13 phage. the mismatched sequences were studied from two points of view, viz 1. the mobility of the fragments on gel electrophoresis in polyacrylamide was ... | 2009 | 2780311 |
| transstadial and attempted transovarial transmission of anaplasma marginale by dermacentor variabilis. | transstadial and transovarial transmission of anaplasma marginale by dermacentor variabilis were attempted with with ticks exposed to the organism once by feeding as larvae or nymphs, and twice by feeding as larvae and nymphs. typical colonies of a marginale were in gut tissues of adults that were infected as larvae, larvae and nymphs, and as nymphs; repeated exposure of ticks did not appear to result in an increase in the number of colonies in the gut of subsequently molted adults nor did it af ... | 1989 | 2782719 |
| detection of colonies of anaplasma marginale in salivary glands of three dermacentor spp infected as nymphs or adults. | salivary glands from males of 3 dermacentor species (d andersoni, d variabilis and d occidentalis) that were infected with either the virginia or idaho isolate of anaplasma marginale as nymphs or adults were examined for colonies of a marginale by use of light and electron microscopy. prior to dissection of salivary glands, exposed ticks were held at 25 c for 15 to 18 days, followed by a 3-day incubation at 37 c. ticks of 2 species transmitted a marginale to calves; the third tick species was co ... | 1989 | 2782720 |
| anti-inflammatory drugs from plant and marine sources. | 2009 | 2784931 | |
| a comparison of coronary risk factors in groups of trained and untrained adolescents. | fifty-five experimental (29 male, 25 female) and 38 control (20 male, 18 female) adolescent subjects participated in this study to investigate the differences in coronary heart disease (chd) risk factors in groups of trained and untrained adolescents. as expected the trained group (both sexes) had higher maximal aerobic power (vo2max) and lower systolic blood pressure at rest. the level of total cholesterol was the same in both groups, but the levels of high-density lipoprotein and its lipoprote ... | 2009 | 2786466 |
| [left ventricular pressure-volume diagram determined by forward and backward formatting of radionuclide ventriculography and analog pressure data]. | pressure-volume (pv) loop is of great value for the assessment of left ventricular (lv) function, but its clinical application has been limited by methodological complexity. a new system was developed to make accurate loop with simplified procedure, and was applied to clinical and interventional study. the system constitutes of a mobile gamma camera, a poly-amplifier and a data processor (gms-550u, toshiba medical) installed in cardiac catheterization labo for simultaneous raw data handling and ... | 2009 | 2786583 |
| neuronal overload in the developing anuran lateral motor column in response to limb removal and thyroid hormone. | the lateral motor column (lmc) in the anuran spinal cord normally undergoes a dramatic reduction in motor neuron number during development. at least two factors influence this process: the limb target which is required for the progression of cell loss, and thyroid hormone, a requisite for metamorphosis. this study has examined the relative and combined effects of limb amputation and exogenous thyroxine, initiated at the onset of normal rapid cell loss in rana pipiens tadpoles, in regulating neur ... | 2009 | 2787336 |
| elevation of factor vii activity and mass in young adults at risk of ischemic heart disease. | the northwick park heart study found that elevation of factor vii in middle-aged subjects was an independent risk factor for subsequent ischemic heart disease. the present study was designed to determine whether factor vii elevation is present at a younger age and whether zymogen or activated factor vii is responsible for this elevation. a group of 20 asymptomatic first degree relatives (mean age 34.9 years) of patients with premature ischemic heart disease were compared with 15 age-matched norm ... | 2009 | 2794283 |
| a simple device for controlling suction force in neurosurgical operations. | a simple and inexpensive device for controlling suction force in neurosurgical operations is described. this device is interposed in the suction tubing on the sterile surgical field. this has the advantage of allowing the surgeon to alter the suction force quickly and easily, according to his or her preference. the total cost is minimal, and the device may be assembled with supplies currently available in most operating rooms. | 2009 | 2797406 |
| a simple device for controlling suction force in neurosurgical operations. | a simple and inexpensive device for controlling suction force in neurosurgical operations is described. this device is interposed in the suction tubing on the sterile surgical field. this has the advantage of allowing the surgeon to alter the suction force quickly and easily, according to his or her preference. the total cost is minimal, and the device may be assembled with supplies currently available in most operating rooms. | 2009 | 2797406 |
| meta-analysis: appropriate tool for the integration of nursing research? | 2009 | 2798158 |