| vaccine efficacy for reducing turbinate atrophy and improving growth rate in piggeries with endemic atrophic rhinitis. | two vaccines, based on formalin-killed whole cells of toxigenic pasteurella multocida type d and bordetella bronchiseptica combined with a partially toxoided cell extract of p multocida, were prepared with freund's incomplete adjuvant (vaccine 1) or by alum precipitation (vaccine 2). each was tested for safety and efficacy in reducing the severity of nasal turbinate atrophy and improving the growth rate of pigs in three western australian commercial piggeries with endemic atrophic rhinitis. in s ... | 1992 | 1627085 |
| transmission of pasteurella multocida on california turkey premises in 1988-89. | restriction endonuclease analysis (rea) of whole-cell dna was used to determine possible sources of pasteurella multocida for each outbreak of fowl cholera occurring in turkey flocks in eight commercial poultry companies in california from october 1988 to september 1989. over this period, 179 isolates of p. multocida were obtained from dead turkeys in 80 meat and breeder flocks on 43 premises. p. multocida was isolated from wildlife on five premises. isolates were characterized by subspecies, se ... | 1992 | 1627098 |
| restriction endonuclease analysis of pasteurella multocida isolates from three california turkey premises. | three california turkey premises that had repeated outbreaks of fowl cholera were studied for periods of 2 to 4 years. using biochemical, serologic, plasmid dna, and restriction endonuclease analyses of isolates of pasteurella multocida from turkeys and wildlife on the premises, strains of the organism were found to be enzootic on two of the premises. on the third, a variety of strains of p. multocida were isolated from fowl cholera outbreak flocks. | 1992 | 1627099 |
| vaccination of turkeys with cell-free culture filtrate of pasteurella multocida: effects of ultrafiltration and endotoxin removal. | cell-free culture filtrate (ccf) of pasteurella multocida strain r44/6 (serotype 3/4/9/12) was fractionated by ultrafiltration into fractions of less than 10,000, greater than 10,000, greater than 30,000, and 10,000 to 30,000 molecular weight (mw). the less-than-10,000-mw fraction contained little endotoxin comparable to bacteriologic medium; the 10,000-to-30,000-mw fraction had a moderate amount of endotoxin, whereas the greater-than-10,000- and greater-than-30,000-mw fractions contained high l ... | 1992 | 1627112 |
| cleavage of immunoglobulin a1, a2 and g by proteases from clinical isolates of pasteurella multocida. | several pasteurella multocida strains were examined for their ability to produce extracellular enzymes that cleave immunoglobulin a and g (ig a and ig g) molecules. two strains isolated from human pulmonary and genital infections produced proteases that cleaved human iga and igg, colostral iga and human myeloma iga1 and iga2. human igm was not degraded by these enzymes. examination of cleavage digests showed two main fragments with different electrophoretic mobilities. the two p. multocida strai ... | 1992 | 1629898 |
| swine leukocyte antigen and macrophage marker expression on both african swine fever virus-infected and non-infected primary porcine macrophage cultures. | swine leukocyte antigens (sla) and a macrophage specific marker were monitored on porcine macrophages cultured with or without macrophage colony stimulatory factor (m-csf) and on cells infected with african swine fever virus (asfv). sla expression was maximal either in the total cell extract or on the cell surface at 3-4 days of culture; after 4 days these values began to decrease. fluorescence analyses of immunostained macrophages cultured with or without m-csf indicated a major upward shift in ... | 1992 | 1632065 |
| use of rats to compare atrophic rhinitis vaccines for protection against effects of heat-labile protein toxin produced by pasteurella multocida serogroup d. | four bacterin-toxoid and three bacterin commercial vaccines against atrophic rhinitis were tested in rats for their capacity to immunize against the lethal and systemic effects of purified heat-labile protein toxin (d-toxin) produced by pasteurella multocida serogroup d. only one bacterin-toxoid vaccine stimulated sufficient immunity to prevent the death of all rats challenged with d-toxin. none of the vaccines prevented weight loss, leukocytosis or increases in serum complement titers in rats c ... | 1992 | 1632076 |
| [results of experimental immunization of calves with different pasteurella antigens]. | calves immunised with different pasteurella antigens (inactivated whole cells, sodium chloride extract) where challenged two weeks after the second immunization with the homologous strain. the intracutaneous application of whole cells of p. haemolytica a1 and p. multocida a was effective. the incidence of pneumonia was reduced and the pneumonic lesions were less severe. the sodium chloride extract was not effective. | 1992 | 1638965 |
| iscom of bhv-1 envelope glycoproteins protected calves against both disease and infection. | a subunit vaccine in the form of immunostimulating complex (iscom) was prepared to contain the envelope glycoproteins of bovine herpesvirus type 1 (bhv-1). this iscom preparation was tested in a vaccination experiment on 4-month-old calves seronegative to bhv-1. in this experiment, four groups with three animals per group were used. two groups were vaccinated with the iscom preparation twice, four weeks apart, one group with 50 micrograms and the other with 100 micrograms per calf. the third gro ... | 1991 | 1653508 |
| heat-labile toxin-producing isolates of pasteurella multocida from rabbits. | five of one hundred forty seven isolates of pasteurella multocida from rabbits were found to produce heat-labile toxin. each isolate was assayed for the ability of potassium thiocyanate (kscn) extracts to cause dermonecrosis in guinea pig skin, ability of bacteria or filtrates to cause cytotoxicity in cell cultures, and reactivity with monoclonal antibodies to heat-labile p. multocida toxin. five capsular type d isolates produced dermonecrosis and reacted with monoclonal antibodies to toxin. fil ... | 1991 | 1658444 |
| clinical pharmacokinetics of parenterally administered danofloxacin in cattle. | danofloxacin is a new fluoroquinolone antibacterial, developed specifically for veterinary use. its in vitro activity and pharmacokinetic properties have been investigated to assess its potential for use in the therapy of respiratory disease in cattle. the minimum inhibitory concentration of danofloxacin against 90% (mic90) of contemporary european and north american field isolates of pasteurella haemolytica, pasteurella multocida and haemophilus somnus, the most important bacterial respiratory ... | 1991 | 1663562 |
| screening rabbit colonies for antibodies to pasteurella multocida by an elisa. | rabbit serum samples from eleven different research facilities were evaluated for the presence of immunoglobulin g against pasteurella multocida by using an enzyme-linked immunosorbent assay (elisa). each facility which submitted serum samples also provided a brief history of each rabbit colony tested. rabbits from colonies reported to have endemic p. multocida or of undetermined status had 83 (58.9%) of 141 rabbits that were positive. colonies reported to be free from p. multocida had 110 (92.4 ... | 1991 | 1666140 |
| partial characterization of plasmids from rabbit isolates of pasteurella multocida. | plasmids have not been reported for isolates of pasteurella multocida from rabbits. we assayed 28 isolates of rabbit p. multocida for plasmids and sought to determine whether or not plasmid presence correlated with clinical or pathologic findings, serotype, toxin production, possession of pili, or biochemical characteristics. fourteen isolates bore a single 1.6 md (covalently closed circular form in 0.7% agarose gels) plasmid. an additional isolate had two plasmids which migrated as a closely-sp ... | 1991 | 1666141 |
| [cubital neuropathy versus tendovaginitis secondary to accidental puncture with inactivated pasteurella multocida]. | | 1991 | 1666961 |
| efficacy of enrofloxacin in the treatment of respiratory pasteurellosis in rabbits. | fourteen new zealand white rabbits with respiratory signs of naturally occurring pasteurella multocida infections were treated with either an injectable or water-soluble oral formulation of enrofloxacin. antimicrobial efficacy was evaluated by scoring clinical signs in the rabbits and recovery of the organisms. seven (87%) of eight rabbits treated with the injectable regimen (5 mg/kg every 12 hours for 14 days) became culture-negative with no clinical signs within 72 hours after initiation of tr ... | 1991 | 1667200 |
| protection against aflatoxin b1-induced hepatocarcinogenesis in f344 rats by 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz): predictive role for short-term molecular dosimetry. | previous studies have demonstrated that dietary administration of the schistosomicidal drug 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz) ameliorates the hepatotoxicity of aflatoxin b1 (afb1). notably, mortality, altered hepatic function, hepatic afb1-dna adduct levels, and expression of hepatic enzyme-altered foci were markedly reduced in the rat by concurrent feeding of oltipraz during exposures to afb1. collectively, these studies prompted us to evaluate the chemoprotective proper ... | 1991 | 1680553 |
| clinical chemical constituents in relation to liver amyloidosis in serum-producing horses. | serum activities of gamma-glutamyl transferase (ggt), alkaline phosphatase (ap), aspartate aminotransferase (ast), and concentrations of total bilirubin and total bile acids were screened during a 5 year period in 27 horses used for production of hyperimmune serum. the horses investigated were regularly immunized with live cultures of the endotoxin-releasing bacteria escherichia coli or pasteurella multocida, the individual animals having undergone such treatment for periods varying from 2 weeks ... | 1991 | 1685737 |
| factors influencing reconstitution by bone marrow transplantation. | reconstitution of levels of pheripheral blood cells following bone marrow transplantation is dependent on the engraftment of the pluripotent hemopoietic stem cells of the transplant. in the case of allogeneic transplants, a successful engraftment carries a high risk of the development of gvhd, which is a serious and often life-threatening complication. t cell depletion of the allogeneic bone marrow graft can completely prevent gvhd provided a sufficient degree of depletion is achieved. experimen ... | 1990 | 1698302 |
| monoclonal antibodies to quebec strain (q17) of bovine rotavirus. | fourteen monoclonal antibodies (mabs) against "quebec" strain (q17) of bovine rotavirus were isolated and characterized. four were specific for viral protein vp7 and ten were specific for viral protein vp6. five different isotypes were represented by this group of antibodies. all of the anti-vp6 and none of the anti-vp7 antibodies were sensitive to the effects of periodate on their antigen. the antibodies could be separated into three groups based on their relative resistance to the dissociation ... | 1990 | 1698323 |
| recombinant derivatives of pasteurella multocida toxin: candidates for a vaccine against progressive atrophic rhinitis. | potential vaccine components for protection against atrophic rhinitis in pigs were developed. this was achieved by deletion mutagenesis of the gene encoding the pasteurella multocida toxin. four purified toxin derivatives lacking different and widely separated regions in the amino acid sequence were characterized by a lack of toxic activity. one such component was shown to induce efficient protection of vaccinated female mice and their offspring against challenge with purified p. multocida toxin ... | 1991 | 1706320 |
| opsonic monoclonal antibodies against lipopolysaccharide (lps) antigens of pasteurella multocida and the role of lps in immunity. | a panel of six monoclonal antibodies (mabs) produced from mice immunized with pasteurella multocida (m1404) (heddleston serotype 2) reacted with homologous lipopolysaccharide, as indicated by enzyme immunoassay and immunoblotting. all six mabs reacted with serotypes 2 and 5 of the 16 heddleston serotypes. the reactive epitopes were localized on the bacterial cell surface by immunogold labelling. the antibodies could agglutinate p. multocida only if cells were first treated with 1 n hcl. all six ... | 1991 | 1709544 |
| evidence of phenotypic dichotomy within an individual pasteurella multocida type strain and among some haemorrhagic septicaemia-causing field isolates. | haemorrhagic septicaemia-causing strains of pasteurella multocida were identified by a disease-specific elisa. some strains, however, were of the same serotype as those which cause haemorrhagic septicaemia (hs) but were negative when tested in the disease specific elisa. the suspect false negative isolates were passaged in mice and retested in the hs elisa with the same result. immunoelectron microscopy was used to examine further these suspect hs-causing strains. monoclonal antibodies and prote ... | 1991 | 1715597 |
| molecular epidemiology of pasteurella multocida in turkeys. | pasteurella multocida isolated from turkeys during an outbreak of fowl cholera was characterized by serotype and heterogeneity of genes encoding rrna (ribotype) to investigate the epidemiology of the organism. isolates were collected between october 1985 and july 1986. the m9 or clemson university fowl cholera vaccine-like strain was detected in 17% of the flocks with fowl cholera. one particular strain, isolated only from breeder flocks, was recovered from 7 of the 10 breeder flocks examined in ... | 1991 | 1718191 |
| detection of stable epitopes on formaldehyde-detoxified pasteurella multocida toxin by monoclonal antibodies. | progressive atrophic rhinitis in pigs can be prevented by vaccination of pregnant sows with formaldehyde-detoxified preparations of either crude extract of toxigenic pasteurella multocida or purified p. multocida toxin (pmt). the protective value of a vaccine is expected to be related to its content of detoxified immunogenic pmt, but previously described methods for detection of pmt cannot be used for the quantification of formaldehyde-detoxified pmt. in contrast to the epitopes on pmt recognize ... | 1991 | 1722064 |
| the dna-dependent and rna-dependent dna polymerase activities of the reverse transcriptases of human immunodeficiency viruses types 1 and 2. | we have constructed a series of plasmids which, when introduced into escherichia coli, induce the overexpression of soluble wild-type and mutated forms of the reverse transcriptases (rts) from human immunodeficiency viruses types 1 and 2 (hiv-1 and hiv-2, respectively). these proteins were analyzed previously for their rna-dependent dna polymerase (rddp) and ribonuclease h (rnase h) activities. in the present study we assayed the different mutant rts for their dna-dependent dna polymerase (dddp) ... | 1991 | 1722105 |
| human immunodeficiency virus type 1 clones chimeric for the envelope v3 domain differ in syncytium formation and replication capacity. | chimeric human immunodeficiency virus type 1 (hiv-1) molecular clones differing only in the envelope v3 region were constructed. the v3 regions were derived from two hiv-1 isolates with a non-syncytium-inducing, non-t-cell-tropic phenotype and from four hiv-1 isolates with a syncytium-inducing, t-cell-tropic phenotype. when assayed in supt1 cells, the two chimeric viruses with a v3 region derived from the non-syncytium-inducing isolates did not induce syncytia and showed a low level of replicati ... | 1992 | 1731110 |
| changes in the microbial flora of airline headset devices after their use. | the bacterial flora of 20 headset devices were evaluated before and after they were worn for 1 hour. bacteria were recovered from all headsets, and their number increased from a mean (+/- standard deviation) of 60 +/- 5 organisms per device to 650 +/- 51 organisms per device (p less than .001). the predominant organisms recovered were staphylococcus spp, streptococcus spp, propionibacterium spp, and peptostreptococcus spp. this study demonstrates the presence of potential pathogens in headset de ... | 1992 | 1731163 |
| application of multivariate analyses of enzymic data to classification of members of the actinobacillus-haemophilus-pasteurella group. | outer membrane vesicles and fragments from actinobacillus actinomycetemcomitans, actinobacillus lignieresii, actinobacillus ureae, haemophilus aphrophilus, haemophilus paraphrophilus, haemophilus influenzae, haemophilus parainfluenzae, pasteurella haemolytica, and pasteurella multocida were isolated and examined semiquantitatively for 19 enzyme activities by using the api zym micromethod. the enzyme contents of vesicles and fragments were compared with the enzyme contents of whole cells of the s ... | 1992 | 1736960 |
| [atrophic rhinitis a.d. 1991]. | in the netherlands the central veterinary institute (cvi) and the animal health services carried out investigations on aetiology, pathogenesis, therapy and prevention of atrophic rhinitis (ar) since 1970. since the discovery of ar toxin in ar pathogenic p. multocida in spf piglets, quicker and cheaper tests were developed e.g. the mouse test and guinea pig skin test. today elisa-tests with poly- and monoclonals are also available. the cvi carried out dna probes and is developing a pcr-test. test ... | 1991 | 1750030 |
| recombinant porcine somatotropin: an immunotoxicology study. | the present study was designed to determine the effect of recombinant porcine somatotropin (rpst; 5, 15, or 25 mg.pig-1.d-1 for 57 d) on a variety of immune function variables. we observed no significant effect of rpst treatment on the gross pathology of the pigs, histopathology of the immune system organs, total and differential white blood cell counts, lymphocyte blastogenic response to mitogens, or the neutrophil functions of chemotaxis, ingestion, reduction of cytochrome c, iodination, and a ... | 1991 | 1752827 |
| pathogenicity of pasteurella multocida a:3 in flemish giant and new zealand white rabbits. | pasteurella multocida a:3 was isolated during an outbreak of pasteurellosis in flemish giant (fg) rabbits. since new zealand white (nzw) rabbits housed in the same room were not as severely affected as fg rabbits, experimental inoculation was undertaken to determine if fg rabbits were more susceptible than nzw rabbits to pasteurellosis induced by this isolate. rabbits of each breed were inoculated with p. multocida a:3 and observed for 3 weeks. four of 5 fg rabbits developed severe clinical dise ... | 1991 | 1753694 |
| the fate of pasteurella multocida after intratracheal inoculation into turkeys. | young adult turkeys were intratracheally inoculated with the p-1059 strain of pasteurella multocida, and the fate of the organism was studied by quantifying the organism in various respiratory and systemic tissues at various times after the inoculation. the results showed that, in the first 2 h, on the order of 10(8) to 10(9) organisms deposited at the upper trachea multiplied in situ to gradually spread downwards to the lower respiratory tract. in the majority of turkeys, by 6 h postinoculation ... | 1991 | 1754542 |
| pasteurella multocida-associated septicaemia in a chital deer (axis axis). | | 1991 | 1755788 |
| correlations of daily activity with avian cholera mortality among wildfowl. | we tested the hypothesis that wildfowl activities can influence the risk of avian cholera (pasteurella multocida infection) for susceptible birds at centerville, humboldt county, california (usa). avian cholera mortality characteristics from past epizootics were correlated with variations in flock size, habitat use and 11 feeding and nonfeeding behaviors among six empirically defined groups of wildfowl: american coots (fulica americana), tundra swans (cygnus columbianus), american wigeon (anas a ... | 1991 | 1758019 |
| distribution of indole-producing urease-negative pasteurellas in animals. | three hundred fifty-six animal isolates of indole-positive urease-negative cultures of pasteurella, which would formerly have been classified as p. multocida, were examined with respect to their relationship to the recently described p. multocida subspecies (ssp.) multocida, septica, and gallicida and p. canis, p. stomatis/taxon 16, and pasteurella sp. b. two hundred sixty-three (73.9%) of the cultures could be identified with one of these taxa, and 93 isolates (26.1%), representing 17 different ... | 1991 | 1760464 |
| identification of vibrio vulnificus o serovars with antilipopolysaccharide monoclonal antibody. | a serotyping scheme for vibrio vulnificus predicated on the detection of lipopolysaccharide (lps) antigens is proposed. the serovar o typing scheme used to type v. vulnificus employs polyclonal antisera raised in rabbits immunized with heat-killed whole-cell vaccines. polyclonal typing sera produced in this manner cross-react with heterologous strains. affinity purification of polyclonal antisera with lps affinity columns resolved some of these cross-reactions; however, affinity-purified polyclo ... | 1991 | 1761690 |
| murine intestinal antibody response to heterologous rotavirus infection. | rotavirus is the most important worldwide cause of severe gastroenteritis. extensive efforts have been devoted to the design of a vaccine that will prevent disease, but development of a more effective vaccine strategy may require progress in the understanding of the mucosal immune response to replicating viral antigens. in this article, we report the characterization of the intestinal antibody response of a murine model to heterologous infection with the rhesus rotavirus vaccine strain. we have ... | 1991 | 1761691 |
| evolution of messenger rna structure and regulation in the genus mus: the androgen-inducible rp2 mrnas. | the rp2 gene is one of several genes that are regulated by androgens in the mouse kidney. previous studies have demonstrated that androgen inducibility of rp2 transcription varies among species within the genus mus, indicating extensive evolutionary modification of the participating regulatory elements. thus, while a five-fold induction of transcription occurs in m. domesticus, none is detectable in m. hortulanus or m. caroli. in the present paper, we have sequenced cdnas representing the rp2 mr ... | 1991 | 1766361 |
| electrophoretic profiles of pasteurella multocida isolates from animals with hemorrhagic septicemia. | we determined that the protein profiles of 14 isolates from animals with hemorrhagic septicemia were relatively homogeneous and could be placed in 2 distinct groups on the basis of their country of origin. such differences correlated with the serotypic properties of the individual isolates; hemorrhagic septicemia isolates of asian and north american origin (carter b) had a major protein band with an apparent molecular mass of 32 kda, whereas those of african origins (carter e) had a major protei ... | 1991 | 1767986 |
| resistance to antimicrobial agents and prevalence of r plasmids in pasteurella multocida from swine. | twenty-nine field isolates of porcine pasteurella multocida were characterized for their capsular and somatic types and were evaluated for their susceptibility to 10 antimicrobial agents. plasmid dna-screening experiments were conducted to determine whether a relationship existed between the presence of plasmids and antibiotic resistance. field isolates of p multocida were susceptible to most of the antimicrobials tested, but all isolates were resistant to clindamycin. eleven isolates of serogro ... | 1991 | 1767987 |
| analysis of high psa n-cam expression during mammalian spinal cord and peripheral nervous system development. | using a monoclonal antibody that recognizes specifically a high polysialylated form of n-cam (high psa n-cam), the temporal and spatial expression of this molecule was studied in developing spinal cord and neural crest derivatives of mouse truncal region. temporal expression was analyzed on immunoblots of spinal cord and dorsal root ganglia (drgs) extracts microdissected at different developmental stages. analysis of the ratio of high psa n-cam to total n-cam indicated that sialylation and desia ... | 1991 | 1769342 |
| characterization of the immunogenicity of formaldehyde detoxified pasteurella multocida toxin. | the immunogenicity of the pasteurella multocida toxin (pmt) was studied in murine model systems. mice were vaccinated with either formaldehyde treated pure pmt (pure toxoid) or formaldehyde treated crude extract of toxigenic p. multocida (crude toxoid). the corresponding mean anti-pmt titres, sero-conversion rates and survival rates after challenge with affinity purified pmt were compared. when assessed both by anti-pmt titres and seroconversion and challenge, pure toxoid was a more potent immun ... | 1991 | 1771750 |
| toxigenic type d pasteurella multocida and progressive atrophic rhinitis in new south wales pig herds. | | 1991 | 1776935 |
| a quantitative measurement of the effect of avian influenza virus on the ability of turkeys to eliminate pasteurella multocida from the respiratory tract. | the effect of avian influenza virus (aiv) infection on the ability of turkeys to eliminate pasteurella multocida from the respiratory tract was evaluated. four-week-old turkeys were experimentally infected with an apathogenic aiv subtype (h5n2) by the oculonasal route and subsequently superinfected with p multocida (urbach strain) by the intranasal route three days after infection with aiv. quantitative clearance of p multocida from the trachea and lung was determined using a pour plate techniqu ... | 1991 | 1780577 |
| effects of antibiotics on the growth and morphology of pasteurella multocida. | the effects of subminimal inhibitory concentrations (submics) of certain antibiotics, namely penicillin g, tetracycline and trimethoprim/sulphamethoxazole, on the growth and morphology of pasteurella multocida were evaluated. submics of penicillin markedly reduced the growth of p. multocida. tetracycline and trimethoprim/sulphamethoxazole had no effect on its growth. submics of penicillin greatly affected the morphology of p. multocida. at the highest concentrations tested (1/2 and 1/4 mic) cell ... | 1991 | 1783910 |
| [isolation and certain properties of the dermonecrotic toxin from pasteurella multocida]. | the procedure for isolation and purification of pasteurella multocida serovariant d toxin has been described. it includes the three steps of protein precipitation from cultural filtrates by 70% ammonium sulfate, chromatography of the concentrated material on ultragel aca44 gel-filtration on sephracryl s-200. the proposed technique permits one the 155-fold purification of the preparation with 32.6% yield estimated by biological activity. the obtained purified preparation is homogeneous in polyacr ... | 1991 | 1784303 |
| interaction of naturally occurring aflatoxins in poultry feed and immunization against fowl cholera. | a total of 1,175 poultry feed samples originating from different farms were analyzed for aflatoxin. poor growth rate and reduced egg production were the main complaints. the rate of contamination with aflatoxin ranged from 10 to 54% of all samples. of samples examined 30.7% proved positive for aflatoxin with a concentration ranging from 1 to 2,000 ppb. outbreaks of fowl cholera were diagnosed on two farms where aflatoxin was detected in the rations used. the impact of aflatoxin in the feed on th ... | 1991 | 1784563 |
| serologic associations between fowl cholera and other diseases. | as part of a case-control study designed to identify fowl cholera risk factors, 2087 blood samples were collected from 71 california meat-turkey flocks. samples were tested for antibodies to three mycoplasmas and four viruses pathogenic for turkeys. flocks that had antibodies to newcastle disease virus and/or mycoplasma meleagridis had an increased risk of having an outbreak of fowl cholera. this information should prove useful for fowl cholera control programs in meat turkeys. | 1991 | 1786004 |
| response of broiler chickens to fowl cholera vaccination at 1 to 6 weeks of age. | broiler chickens, in groups of 10, received a single vaccination by the stick-wing route at 1, 2, 3, 4, 5, 6, or 11 weeks of age with live clemson university strain of pasteurella multocida. twenty non-vaccinates kept in isolation served as controls. cholera serum antibody titers in all chickens were determined by enzyme-linked immunosorbent assay at weekly intervals. chickens vaccinated once at 1, 2, 3, 4, 5, and 6 weeks, respectively, attained 25.2%, 28.7%, 34.7%, 46.2%, 51.8%, and 64.6% of th ... | 1991 | 1786010 |
| genetic variation in resistance of turkeys to experimental challenge with pasteurella multocida. | six hundred fifty-five male and female turkeys representing four genetic lines were challenged in 10 experiments over a 3-year period with a field isolate of pasteurella multocida. poults were challenged at 45 days of age with 1 ml of an inoculum containing 1.2 x 10(7) bacteria per ml. the lines of turkeys included two randombred control lines (rbc1 and rbc2), a subline (e) of rbc1 selected for increased egg production, and a subline (f) of rbc2 selected for increased 16-week body weight. the nu ... | 1991 | 1786025 |
| genomic distribution of a serotype 1-specific antigen-coding dna fragment of pasteurella haemolytica. | a genomic fragment of pasteurella haemolytica biotype a coding for a serotype 1-specific agglutinating antigen was used as a probe in a series of hybridization experiments to determine distribution of the fragment in various p. haemolytica serotypes as well as other bacteria. results showed presence of the fragment in seven out of the 12 serotypes tested, all of which belonged to biotype a. two other serotypes belonging to biotype a, all three serotypes belonging to biotype t, two pasteurella mu ... | 1991 | 1789017 |
| characterization and comparison of antimicrobial susceptibilities and outer membrane protein and plasmid dna profiles of pasteurella haemolytica and certain other members of the genus pasteurella. | the outer membrane protein (omp), plasmid, and antimicrobial resistance profiles of pasteurella haemolytica serotypes 1 through 12, a bovine isolate of p multocida, a chicken isolate of p multocida, and an unidentified pasteurella species of bovine origin were examined. isolates of p haemolytica serotypes belonging to the same biotype possessed similar omp profiles. biotype a isolates contained 2 prominent omp of 43 kilodaltons (kd) and 29 kd, whereas biotype-t serotypes contained 3 major omp of ... | 1991 | 1789515 |
| the microbial flora of the respiratory tract in feedlot calves: associations between nasopharyngeal and bronchoalveolar lavage cultures. | the upper and lower respiratory tracts of 59 feedlot calves with clinical signs of naturally occurring respiratory disease (cases) and 60 comparison (control) animals were cultured before treatment, using nasopharyngeal swabs (nps) and bronchoalveolar lavage (bal). the most prevalent organisms were pasteurella multocida and mycoplasma bovis. isolations of p. multocida from nps and bal fluid were found to be significantly associated with morbidity (p less than or equal to 0.05), but the frequency ... | 1991 | 1790489 |
| [a case of pasteurella multocida subsp. multocida complicated with diabetes mellitus]. | we report a case of sepsis who died caused by pasteurella multocida subsp. multocide sepsis. a 68-year-old male was admitted to azusawa hospital because of disturbance of consciousness. he had been suffering from diabetes mellitus combined with gangrene, but received no treatment. the patient died 24 h after hospitalization, and pasteurella multocida subsp. multocida was isolated from his blood. laboratory tests showed that crp; 5+ wbc; 15,400/microliters, tp; 5.2 g/dl. although pasteurella mult ... | 1991 | 1791335 |
| report of 4 cases of pasteurella multocida septic arthritis. | pasteurella multocida is frequently responsible for infections in man due to wounds inflicted by animals (generally cats or dogs). however, the development of septic arthritis is a rare complication. we report 4 cases of pasteurella multocida septic arthritis with demonstration of the organism in the joint in each case. two cases presented with monoarthritis (sternoclavicular joint and wrist) and 2 cases had polyarticular involvement from the outset. | 1991 | 1795328 |
| structural characterization of the urinary metabolites of iprindole in rat. | 1. the in vivo metabolism of iprindole in rat is described. each rat received a single dose of iprindole (10 mg/kg) and urine was collected for 48 h. 2. fourteen metabolites of iprindole were isolated from rat urine after enzymic hydrolysis and their structures were determined by a computerized g.l.c.-mass spectrometric technique, before and after appropriate chemical derivatization. 3. three concurrent metabolic pathways have been identified for iprindole in rat; aromatic ring hydroxylation is ... | 1991 | 1796616 |
| in vitro binding of pasteurella multocida cell wall preparations to tracheal mucus of cattle and swine and to a tracheal epithel cell wall preparation of cattle. | outer membrane preparations of various pasteurella isolates (pasteurella multocida and some other pasteurella species) from cattle and swine were extracted by n-lauryl-sarcosine sodium salt. capsular extracts were prepared by heat treatment. both preparations bound to epithel cell wall preparations (ecw) of trachea from cattle and to tracheal mucus of cattle and swine. binding was demonstrated by an enzyme-linked immunosorbent assay (elisa). distinct high adherence values were shown by the great ... | 1991 | 1796684 |
| plasmid-mediated rob-1 beta-lactamase in pasteurella multocida from a human specimen. | a pasteurella multocida human isolate was resistant to beta-lactams because of production of rob-1 beta-lactamase. the beta-lactamase was encoded by a 4.3-kb plasmid closely related to that of a pasteurella bovine strain, as shown by sau3a restriction profile and hybridization with a plasmid probe containing the blarob-1 gene. | 1991 | 1804018 |
| an abattoir survey of pneumonia and pleuritis in slaughter weight swine from 9 selected herds. iv. bacteriological findings in chronic pneumonic lesions. | a total of 855 pig lungs were collected at slaughter and evaluated macroscopically. bacteriological examinations were carried out on tissue samples from chronic pleuropneumonic lesions (n = 196) and from chronic bronchopneumonic lesions with suppuration (n = 14). samples from normal lung tissue (n = 22) were also included. pasteurella multocida was isolated from 54%, actinobacillus (haemophilus) pleuropneumoniae from 11%, and streptococcus spp. from 14% of the pneumonic lesions, respectively. fr ... | 1991 | 1814189 |
| induction of pneumonia in rabbits by use of a purified protein toxin from pasteurella multocida. | heat-labile toxin from a cell sonicate of a virulent type-d strain of pasteurella multocida was purified by ammonium sulfate precipitation followed by ion exchange chromatography, gel filtration chromatography, and polyacrylamide gel electrophoresis. toxic activity was assayed during toxin purification by cytopathic effect in vero or bovine embryonic lung cell cultures. toxicity for cells correlated with dermonecrosis in guinea pig skin. toxicity was accounted for by a single protein with a mole ... | 1991 | 1826990 |
| the development of macrolides: clarithromycin in perspective. | macrolide antibiotics have been available and used clinically since 1952. the class of drugs originated from a soil sample obtained from the city of ilo-ilo on the island of paray in the philippines. erythromycin has been the most widely used agent of this class called 'macrolides' because they possess the macrocyclic lactone nucleus. many esters of erythromycin are well established as agents to treat a variety of respiratory and cutaneous infections, particularly in children. there has been a r ... | 1991 | 1827094 |
| proteins and antigens of pasteurella multocida serotype 1 from fowl cholera. | the protein profiles of pasteurella multocida serotype 1 isolates and the response of chickens to serotype 1 antigens were investigated using sds-page. patterns obtained with coomassie blue staining of soluble protein extracts were similar. the major difference between isolates was the position of one of the major proteins in the 34-38 kda region. when chickens were experimentally infected with a clinical isolate of p. multocida serotype 1 various proteins were recognised by immunoblotting, incl ... | 1991 | 1829560 |
| peritoneal macrophage response: an in vivo model for the study of synthetic materials. | this study was designed to validate an in vivo model in rat to study cell-implant interactions. pieces of dacron and goretex and polydimethylsiloxane (reference material) precoated or not were implanted in the peritoneal cavity. in some cases the peritoneal cells were stimulated before the implantation. macrophage phagocytosis and fibrinocoagulolytic activities were investigated in parallel with morphological studies 6 h after implantation. a graded cell response related to the different situati ... | 1991 | 1831674 |
| peritoneal macrophage response: an in vivo model for the study of synthetic materials. | this study was designed to validate an in vivo model in rat to study cell-implant interactions. pieces of dacron and goretex and polydimethylsiloxane (reference material) precoated or not were implanted in the peritoneal cavity. in some cases the peritoneal cells were stimulated before the implantation. macrophage phagocytosis and fibrinocoagulolytic activities were investigated in parallel with morphological studies 6 h after implantation. a graded cell response related to the different situati ... | 1991 | 1831674 |
| reproduction of turbinate atrophy in pigs by intranasal consecutive-day inoculation with suspensions of a toxigenic serotype d strain of pasteurella multocida. | | 1991 | 1832039 |
| vaccination against progressive atrophic rhinitis with a recombinant pasteurella multocida toxin derivative. | vaccination against progressive atrophic rhinitis using a purified recombinant derivative of the pasteurella multocida toxin (pmt), was carried out. ten pregnant gilts were vaccinated twice with the nontoxic derivative (do) which apart from a lack of 121 amino acids had an amino acid sequence identical to pmt, while seven gilts were vaccinated with a purified, formaldehyde treated, native pmt and ten gilts served as non-vaccinated controls. the resulting piglets were inoculated intranasally with ... | 1991 | 1832079 |
| [the significance of the dermonecrotic toxin of p. multocida serovar d in the pathogenesis of pneumonia in swine]. | the intratracheal application of crude and purified toxin of p. multocida serovar d in primary spf-piglets resulted, apart from turbinate atrophies, in lobular to lobularly confluent catarrhalic pneumonias. | 1991 | 1833939 |
| a novel approach to detect toxin-catalyzed adp-ribosylation in intact cells: its use to study the action of pasteurella multocida toxin. | certain microbial toxins are adp-ribosyltransferases, acting on specific substrate proteins. although these toxins have been of great utility in studies of cellular regulatory processes, a simple procedure to directly study toxin-catalyzed adp-ribosylation in intact cells has not been described. our approach was to use [2-3h]adenine to metabolically label the cellular nad+ pool. labeled proteins were then denatured with sds, resolved by page, and detected by flurography. in this manner, we show ... | 1991 | 1835459 |
| growth hormone concentrations in plasma of healthy pigs and pigs with atrophic rhinitis. | plasma concentrations of porcine growth hormone (pgh) were similar in healthy pigs and those with atrophic rhinitis (ar), therefore, observed reduced growth rates and feed efficiency in naturally infected pigs with ar were not attributed to low concentrations of plasma pgh. also, pituitary glands in both groups of pigs were responsive to growth hormone-releasing hormone (ghrh) challenge by increasing pgh secretion. administration of clonidine hydrochloride to pigs naturally infected with ar fail ... | 1991 | 1837428 |
| prevention and treatment of atrophic rhinitis in pigs with getroxel, chlorquinaldol and oxytetracycline. | the sensitivity of ten bordetella bronchiseptica and ten pasteurella multocida strains, each isolated from cases of atrophic rhinitis (ar), was examined in tube dilution test. getroxel, chlorquinaldol and oxytetracycline and the former two ones combined with trimethoprim inhibited the growth of both species in vitro. the minimum inhibitory and the minimum bactericidal concentration was less than 0.5 microgram/ml. when efficacy was tested in spf in the group fed a combination of getroxel, chlorqu ... | 1991 | 1838458 |
| effects of purified pasteurella multocida dermonecrotoxin on the nasal ventral turbinates of fattening pigs: histological observations. | fattening specific pathogen-free derived pigs were injected intramuscularly with dermonecrotoxin of pasteurella multocida, capsular type d. ten days later, the nasal ventral turbinates and liver were examined histologically. a moderate turbinate atrophy was observed due to an increased number of osteoclasts and the absence of intramembranous bone apposition. liver lesions were limited to some hepatocyte necrosis, sinusoid neutrophil infiltration and kupffer cell hypertrophy. this study demonstra ... | 1991 | 1838708 |
| evidence for non-siderophore-mediated acquisition of transferrin-bound iron by pasteurella multocida. | two clinical isolates of pasteurella multocida associated with bovine pneumonia were examined for iron acquisition. both isolates were capable of obtaining iron for growth from bovine but not from human, avian, equine or porcine transferrin. this correlated with specific binding of bovine transferrin by iron-limited cells or isolated membranes. no siderophore was detected in the strains by a general screening assay. in response to iron-limited conditions, a number of high molecular mass iron-reg ... | 1991 | 1839048 |
| a new case of meningitis due to pasteurella multocida. | | 1991 | 1845357 |
| atp-dependent partitioning of the dna template into supercoiled domains by escherichia coli uvrab. | the helicase action of the escherichia coli uvrab complex on a covalently closed circular dna template was monitored using bacterial dna topoisomerase i, which specifically removes negative supercoils. in the presence of e. coli dna topoisomerase i and atp, the uvrab complex gradually introduced positive supercoils into the input relaxed plasmid dna template. positive supercoils were not produced when e. coli dna topoisomerase i was replaced by eukaryotic dna topoisomerase i or when both e. coli ... | 1991 | 1847511 |
| expression of human papillomavirus proteins in yeast saccharomyces cerevisiae. | the l1 and l2 proteins of human papillomavirus (hpv) types 1, 6, and 16 and the e6 and e7 proteins of hpv 16 were expressed in saccharomyces cerevisiae. the yeast expressed proteins were readily detected by immune blotting and were generally intact. the hpv 1 l1 and l2 proteins expressed in yeast were indistinguishable from the major and minor capsid proteins purified from hpv 1 virions as judged by gel electrophoresis and immunoblotting. the hpv 6 and hpv 16 l2 proteins and hpv 16 e7 proteins w ... | 1991 | 1850917 |
| comparison of live avirulent m-9, minnesota, and cu fowl cholera vaccines. | the m-9 and minnesota (mn) avirulent pasteurella multocida vaccines were evaluated and compared with the clemson university (cu) vaccine, which had been shown to be highly effective in preventing fowl cholera in turkeys. neither the m-9 nor the mn vaccine given in the drinking water was as effective as the cu vaccine in protecting turkeys against challenge with virulent p. multocida. when grown in brain-heart infusion (bhi) agar as recommended, the m-9 was not as efficacious as when it was grown ... | 1991 | 1854311 |
| in vivo antigen expression by pasteurella multocida. | pasteurella multocida was purified from the blood of turkeys affected with acute fowl cholera, and membrane preparations from those bacteria were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and visualized on immunoblots. antigens were detected in the membranes of these in vivo-propagated bacteria that were not detected in membrane preparations of the same p. multocida strain grown in vitro. the unique antigens were detected in the detergent-insoluble phase and were enr ... | 1991 | 1854322 |
| pasteurella multocida peritonitis in capd: beware of the cats. | | 1991 | 1854879 |
| quantitative study of striate single unit responses in monkeys performing an orientation discrimination task. | contour orientation discrimination accuracy is determined by the orientation bandwidth, response variance and response strength of single units that code for orientation. we measured the latter three properties for v1 cells of monkeys which were performing an orientation discrimination of the grating stimulating the cell under study. we recorded from 285 cells, of which 76% responded to the grating. the orientation bandwidth, measured as full width at half height of the tuning curve, varied over ... | 1991 | 1855551 |
| [new osmotic additives to culture media for corneal preservation]. | we investigated the effect of hyaluronic acid, molecular weight 250,000 and 500,000 as an osmotic additive to corneal preservation media. porcine corneal specimens were incubated in organ culture for 8 days, followed by endothelial cell count and ultrasonic pachymetry. the preservation medium mem-earle with 2% fcs contained either no additives, 6% dextrane, mw 500,000 2% chondroitin sulfate, 1% hyaluronic acid mw 250,000, or 1% hyaluronic acid, mw 500,000. whereas corneal thickness was estimated ... | 1991 | 1855724 |
| [new osmotic additives to culture media for corneal preservation]. | we investigated the effect of hyaluronic acid, molecular weight 250,000 and 500,000 as an osmotic additive to corneal preservation media. porcine corneal specimens were incubated in organ culture for 8 days, followed by endothelial cell count and ultrasonic pachymetry. the preservation medium mem-earle with 2% fcs contained either no additives, 6% dextrane, mw 500,000 2% chondroitin sulfate, 1% hyaluronic acid mw 250,000, or 1% hyaluronic acid, mw 500,000. whereas corneal thickness was estimated ... | 1991 | 1855724 |
| enhanced interstitial fluid adenosine attenuates myocardial stunning. | reversible myocardial dysfunction associated with transient ischemia has been termed the stunned myocardium. because exogenous adenosine has been shown to protect the ischemic myocardium, we hypothesized that augmentation of endogenous adenosine levels would attenuate myocardial stunning. to induce stunning, anesthetized dogs were subjected to 15 minutes of ischemia (left anterior descending artery occlusion) followed by 60 minutes of reperfusion. erythro-9-(2-hydroxy-3-nonyl) adenine (ehna; 5 m ... | 1991 | 1858025 |
| ultrastructural localization of the pasteurella multocida toxin in a toxin-producing strain. | toxigenic strains of pasteurella multocida produce the 147 kda protein pasteurella multocida toxin (pmt) which is responsible for the osteoclastic bone resorption in progressive atrophic rhinitis in pigs and induces such resorption in all experimental animals tested so far. in the present study we have carried out immunocytochemistry on formaldehyde- and glutaraldehyde-fixed ultracryocut p. multocida using a pool of monoclonal antibodies against different epitopes on pmt as the first layer and a ... | 1991 | 1865180 |
| pasteurella multocida: zoonotic cause of peritonitis in a patient undergoing peritoneal dialysis. | | 1991 | 1867248 |
| pasteurella multocida infection in a patient with aids. | | 1991 | 1870343 |
| meningitis from canine pasteurella multocida following mastoidectomy. | a case of pasteurella multocida meningitis, following a mastoidectomy is presented. the association of close contact with pets, many of which harbour pasteurella multocida as part of their normal buccal flora. this case confirms the potential benefit of taking an ear swab prior to mastoid surgery and in seeking an appropriate 'pet' history. | 1991 | 1875142 |
| high risk of squamous cell carcinoma of the cervix for women with hla-dqw3. | many immune responses are controlled by genes of the major histocompatibility complex (mhc). in man these include the loci encoding the hla-a, -b, -c, -dr, -dq and -dp antigens, and many diseases have been linked with these. but attempts to identify hla genes in man that might explain why an immune response against malignant tumours should be ineffective have so far been disappointing, apart from the association reported between the hla-dr1 antigen and a susceptibility to a rare carcinoma of the ... | 1991 | 1876187 |
| acetylcholinesterase from schistosoma mansoni: immunological characterization. | the enzyme acetylcholinesterase (ache) is present in the trematode schistosoma mansoni, which infects humans and causes a severe disease called schistosomiasis or bilharzia. we have purified this enzyme and raised polyclonal antibodies against it. the specificity of these antibodies against the schistosome enzyme was demonstrated by their capacity to precipitate exclusively ache activity from cercariae extract and to recognize the 8s molecular form of the parasite's ache. on the other hand, they ... | 1991 | 1885212 |
| the protein sequence responsible for lipoprotein membrane localization in escherichia coli exhibits remarkable specificity. | structural information defining an n-terminal sequence required for the membrane sorting of bacterial lipoproteins has been previously garnered through the study of a hybrid outer membrane (om) lipo-beta-lactamase (ll) (ghrayeb and inouye (1984) j. biol. chem. 259, 463-467). introduction of an aspartate as the second residue of mature ll (d2 mutant) causes an inner membrane (im) localization of this protein (yamaguchi, k., yu, f., and inouye, m. (1988) cell 53, 423-432). introduction of as aspar ... | 1991 | 1885579 |
| detection and enumeration of toxin-producing pasteurella multocida with a colony-blot assay. | colonies of toxin-producing pasteurella multocida were detected with peroxidase-labeled monoclonal antibodies by a membrane assay. examination of the specificity of the assay with 29 p. multocida cultures representing various geographic origins, hosts, and serotypes indicated that the test was specific for toxin-producing strains. no cross-reactions were observed with bordetella species that can be associated with p. multocida in producing diseases in animals. a single membrane could be used to ... | 1991 | 1885729 |
| pasteurella haemolytica endocarditis. | although human infections with bacteraemia due to pasteurella multocida are not uncommon, endocarditis associated with p. haemolytica is rare. we describe such a case in which the patient died despite treatment with apparently appropriate antimicrobial agents. | 1991 | 1885915 |
| relationship between the iron regulated outer membrane proteins and the outer membrane proteins of in vivo grown pasteurella multocida. | the sds-page patterns of the outer membrane protein (omp) extracts of pasteurella multocida strain p1059, grown under iron-restricted, iron-replete and in vivo conditions, were examined. the results showed that the iron-regulated outer membrane proteins (iromps) with molecular masses of 76 kda, 84 kda, and 94 kda were expressed by bacteria grown in iron-restricted media. they were also expressed by in vivo grown p. multocida. convalescent-phase sera, obtained from turkeys which had survived past ... | 1991 | 1887567 |
| toxigenic pasteurella multocida in rabbits with naturally occurring atrophic rhinitis. | in a commercial rabbitry nasal swabs were taken from 36 animals with enzootic upper respiratory disease resembling porcine atrophic rhinitis. 35 pasteurella multocida strains were isolated from 17 rabbits. among 30 strains tested for dermonecrotic toxin production 3, derived from 3 animals, were positive in the guinea pig skin test. 15 bordetella bronchiseptica strains were recovered from 14 rabbits. no toxigenic strains were found among 6 isolates tested using the same method. | 1991 | 1887698 |
| pasteurella multocida septicaemia in fallow deer (dama dama). | thirteen of 100 fallow deer, aged between 6 months and 10 years, died over a 5 week period. the deaths occurred in 2 outbreaks 3 weeks apart. both outbreaks were preceded by at least 3 days of cold wet and windy weather, and were associated with water-logged pastures. affected animals were usually found dead, with a frothy blood-stained nasal discharge. in the 8 deer necropsied, gross lesions included widespread subserosal petechial haemorrhages, severe pulmonary congestion and oedema with froth ... | 1991 | 1888312 |
| atrophic rhinitis caused by pasteurella multocida type d: morphometric analysis. | in order to study the distribution and the extent of atrophy caused by pasteurella multocida in the nasal conchae, experimental piglets were injected intramuscularly at seven days of age with either two or four 50% mouse lethal doses per kg body weight of p. multocida type d dermonecrotoxin. experimental and control piglets were killed four, six and ten days postinjection. serial transverse paraffin embedded sections of the noses were cut throughout the entire length of the nasal conchae. the ar ... | 1991 | 1889032 |
| naturally acquired pasteurella multocida infection in rabbits: clinicopathological aspects. | a cohort of 41 new zealand white rabbits, 35 to 60 days old, from twelve litters were followed for twelve weeks for development of pasteurellosis. eleven of 19 rabbits in five litters acquired pasteurella multocida infection. the incubation period was difficult to determine as p. multocida infection was detected both before and after the onset of rhinitis. the response of rabbits to infection varied from subclinical infection to death from systemic pasteurellosis. atrophy of the maxilloturbinate ... | 1991 | 1889034 |
| in vitro antimicrobial susceptibility of pasteurella haemolytica and pasteurella multocida recovered from cattle with bovine respiratory disease complex. | the antimicrobial susceptibilities of 421 pasteurella haemolytica and 158 p. multocida isolates recovered from cattle with respiratory disease were determined with a microdilution minimal inhibitory concentration test system. isolates were analyzed for patterns of resistance to ampicillin, ceftiofur, erythromycin, gentamicin, penicillin, spectinomycin, sulfachlorpyridazine, sulfadimethoxine, tetracycline, and tylosin. all isolates tested were found susceptible to ceftiofur and sulfachlorpyridazi ... | 1991 | 1892929 |
| experimental model of atrophic rhinitis in gnotobiotic pigs. | to study the pathogenesis of atrophic rhinitis, gnotobiotic pigs (n = 6) were inoculated intranasally with a sterile sonicate of a toxigenic strain of bordetella bronchiseptica (0.16 mg of protein per ml) at 5 days of age, and they were then inoculated intranasally with 1 ml (5,250 cfu/ml) of a live, toxigenic strain of pasteurella multocida at 7 days of age. pigs were necropsied at 2, 5, 9, 14, 21, and 28 days postinoculation; those pigs necropsied after 5 days had developed turbinate atrophy. ... | 1991 | 1894365 |
| adherence of pasteurella multocida isolated from pigs and relationship with capsular type and dermonecrotic toxin production. | pasteurella multocida can often be isolated from pneumonic lungs in pigs. there is little information about the pathogenesis of this infection. attachment of microorganisms to eucaryotic cells is considered to be a prerequisite for colonization of the host in the pathogenesis of bacterial infections. forty-seven p multocida strains isolated from pigs in france, and belonging to capsular type a or d were tested for their ability to agglutinate human erythrocytes, and to adhere to tracheal and lun ... | 1991 | 1897871 |
| statistical evidence for a link between bronchopneumonia and disseminated focal nephritis in pigs. | an investigation on the occurrence of different pneumonia types and their possible concurrence with other pluck organ disorders was made on 6,565 pigs presented at slaughter. the frequency of disseminated focal nephritis in a bronchopneumonia group and a non-bronchopneumonia residual group, respectively, was found to differ significantly from the mean frequency of nephritis in all pig plucks examined. the number of lesioned kidneys in each of 28 samples contributing to the bronchopneumonia group ... | 1991 | 1907788 |