| biochemical and functional characterization of the leucocyte tyrosine phosphatase cd45 (cd45ro, 180 kd) from human neutrophils. in vivo upregulation of cd45ro plasma membrane expression on patients undergoing haemodialysis. | the biochemical and functional characterization, and the regulation of plasma membrane expression of the leucocyte tyrosine phosphatase cd45, have been investigated in neutrophils from healthy donors and patients undergoing haemodialysis. cd45 proteins of 180 kd and 130-150 kd were precipitated from neutrophils from both healthy subjects and haemodialysed patients. prolonged storing, as well as trypsin treatment of samples containing the 180-kd cd45 protein, generated the 130-150-kd polypeptides ... | 1992 | 1370931 |
| zidovudine-interferon-alpha combination therapy in patients with advanced human immunodeficiency virus type 1 infection: biphasic response of p24 antigen and quantitative polymerase chain reaction. | in an open-label dose-ranging pilot trial, 13 homosexual men with human immunodeficiency virus type 1 (hiv-1) p24 antigenemia after at least 6 weeks of zidovudine monotherapy were continued on zidovudine and given interferon-alpha, 1.25-7.5 x 10(6) units/m2 subcutaneously three times/week. plasma p24 antigen levels demonstrated a biphasic response, falling initially in 11 patients by a mean of 50% (95% confidence interval, 36%-64%; p = .001) at a median of 11 weeks, but rising steadily thereafte ... | 1992 | 1349031 |
| experimental atrophic rhinitis in 2 and 4 month old pigs infected sequentially with bordetella bronchiseptica and toxigenic type d pasteurella multocida. | experimental infections with bordetella bronchiseptica and/or toxigenic type d pasteurella multocida were studied in 2- and 4-month-old primary specific-pathogen-free pigs. none of the 2-month-old pigs inoculated with b. bronchiseptica or p. multocida alone developed turbinate atrophy. all the pigs inoculated with b. bronchiseptica (10(7) cfu/head) and p. multocida (10(9) cfu/head for 5 consecutive days) together, however, developed clinical and post-mortem signs of atrophic rhinitis (ar) simila ... | 1992 | 1385667 |
| naturally occurring soluble cd4 in patients with human immunodeficiency virus infection. | to investigate its use as a marker of disease severity, serum soluble cd4 (scd4) was measured by elisa in patients with human immunodeficiency virus (hiv) infection. levels of scd4 were higher in patients than in controls (p less than .001) but did not increase with disease severity. scd4 release per cd4 lymphocyte showed a linear increase with disease severity and performed as well as beta 2-microglobulin, a widely used marker. to study the role of scd4 in the pathogenesis of hiv infection, an ... | 1992 | 1349032 |
| [clinicobacteriological study of pasteurella multocida as a zoonosis (1). condition of dog and cat carriers of pasteurella, and the influence for human carrier rate by kiss with the pets]. | pasteurella multocida is a gram-negative short rod-shaped bacteria, which is a part of the indigenous flora of the oral cavity of many animals other than man. the number of reports on cases of infections with this bacterium due to animal bites and/or scratches, bacterial infections of the respiratory tract, sepsis due to this organism and death caused by the bacteria have been increasing in recent years. we investigated p. multocida in the hair and oral cavity of 3 dogs and 29 cats according to ... | 1992 | 1402084 |
| [the first report of human chronic sinusitis by pasteurella multocida subsp. multocida in japan]. | a 53-year-old male visited our hospital due to nasal obstruction persisting for 6 months and constant rhinorrhea. pasteurella multocida subsp. multocida was isolated from his nasal discharge and lavage fluid of the maxillary sinus, and also from the oral cavity of the dog he kept. the bacterial strains isolated from the patient and dog were identical in terms of biochemical properties, and drug sensitivity. although serotype was different, the strain from the patient showed (a:6) and that from h ... | 1992 | 1402086 |
| expression of a single lignin peroxidase-encoding gene in phanerochaete chrysosporium strain me446. | a previously described linked set of lignin peroxidase-encoding genes (lpo) from phanerochaete chrysosporium (p.c.) me446 is not expressed under standard growth conditions for ligninolytic activity. however, a single unlinked lpo gene, not previously described in p.c. strain me446, is expressed. the transcription start points of this gene are mapped and the gene is assigned to a genetic linkage group by the use of restriction-site polymorphism segregation analysis. no transcripts from lpo-relate ... | 1992 | 1351020 |
| comparison of dna fingerprints and somatic serotypes of serogroup b and e pasteurella multocida isolates. | the dna fingerprint profiles and somatic serotypes of 71 pasteurella multocida capsule serogroup b isolates, 13 capsule serogroup e isolates, and 16 somatic reference serotype strains were compared. each of the 16 reference somatic serotypes had a unique dna fingerprint profile with the hhai restriction endonuclease. fifty-four serogroup b isolates (isolated from classical cases of hemorrhagic septicemia) reacted with somatic serotype 2 or 5 antiserum and had dna fingerprint profiles which resem ... | 1992 | 1378060 |
| toxigenic type a pasteurella multocida as a causative agent of nasal turbinate atrophy in swine. | although no clinical signs of atrophic rhinitis (ar) were recognized in 2- and 5-week-old pigs, approximately 60% of 2- to 6-month-old pigs showed clinical signs of ar in an affected pig farm. none of the pigs had normal turbinate at slaughter. bordetella bronchiseptica was not isolated from any of the pigs before onset and incipient stage of the outbreak (2-week to 2-month-old). pasteurella multocida of capsular type d was not isolated from any of those pigs. however, toxigenic p. multocida of ... | 1992 | 1386531 |
| pasteurella multocida infection of a total hip arthroplasty. a case report. | the authors report a case history of a diabetic woman requiring revision hip arthroplasty of a charnley total hip prosthesis that was infected with pasteurella multocida. the infection of the loose prosthesis followed a cat bite to the same leg. advice is given on the management of patients with infection following animal inoculations, and the subject of increased risk with a loose prosthesis is discussed. | 1992 | 1402948 |
| acquired immunity to larvae of amblyomma marmoreum and a.hebraeum by tortoises, guinea-pigs and guinea-fowl. | a study of acquired resistance in guinea-pigs, guinea-fowl and tortoises to larvae of the ticks amblyomma hebraeum koch and a.marmoreum koch (acari: ixodidae) showed that repeated infestations of the laboratory host resulted in a 29.3-49.4% reduction respectively in weight of engorged larvae. no resistance was induced in guinea-fowl, the natural host for larvae of both species. a small decline in the mean weight of engorged larvae was observed for both species of ticks after three successive inf ... | 1992 | 1421505 |
| changes in the bacterial flora of the upper and lower respiratory tracts and bronchoalveolar lavage differential cell counts in feedlot calves treated for respiratory diseases. | serial nasopharyngeal swab and bronchoalveolar lavage cultures were used to estimate changes in the bacterial flora of the respiratory tracts of calves during the first month after arrival in the feedlot. bronchoalveolar lavage (bal) differential cell counts served to evaluate pulmonary inflammatory changes during this period. two groups of calves were studied, one consisting of clinically normal controls (n = 60), the other, of cases (n = 59) which received treatment for respiratory disease (pe ... | 1992 | 1423052 |
| enhanced adherence of pasteurella multocida to porcine tracheal rings preinfected with bordetella bronchiseptica. | adherence of 25 isolates of pasteurella multocida to porcine tracheal rings was evaluated. results indicated that adherence was not related to the isolate's origin, capsular or somatic types, dermonecrotoxin production or hemagglutination activity. the effect of a preinfection with bordetella bronchiseptica on the colonization by p. multocida was then studied. on rings infected with p. multocida alone, bacteria initially adhered to the epithelium, but within a few hours, the level of colonizatio ... | 1992 | 1423064 |
| the nysb sund double mutant of dictyostelium discoideum is blocked in the acquisition of non-degradative resistance to the pea phytoalexin pisatin. | dictyostelium discoideum amoebae can be induced to acquire a non-degradative resistance to the pea phytoalexin pisatin. the nysb sund double mutant is blocked in the acquisition of this resistance. using parasexual genetics it has been shown that sund is a recessive mutation linked to nysb on linkage group vi. | 1992 | 1426988 |
| cat-scratch salpingitis. | | 1992 | 1406855 |
| light microscopic and ultrastructural pathology of seminiferous tubules of rats given multiple doses of pasteurella multocida group d protein toxin. | male holtzman rats were given subcutaneous doses of a purified pasteurella multocida group d heat-labile toxin on alternate days for up to 22 days. rats were necropsied at 18 days or 36 days (14 days after last dose of toxin) or when moribund, and testicles were taken for histologic and ultrastructural examination. other selected tissues, including liver and spleen, were taken for histologic examination. histologically, testicular and splenic lesions occurred more consistently and at much smalle ... | 1992 | 1411123 |
| severe pasteurella multocida infections in pregnant women. | we report 2 cases of severe infections due to pasteurella multocida, both occurring during pregnancy in previously healthy women. both women had contact with animals (dog and cat) but neither of them had been bitten. apart from a slight decrease in igg levels, no immunological defects could be detected. both women had received oral phenoxymethylpenicillin in the early phase of the disease, but still fell ill with severe infections. one woman had meningitis while the other suffered from celluliti ... | 1992 | 1411311 |
| effects of sub-mics of antibiotics on cell surface characteristics and virulence of pasteurella multocida. | the effects of sub-mics of certain antibiotics, namely, penicillin g, tetracycline, and trimethoprim-sulfamethoxazole, on the cell surface characteristics and the virulences of two toxigenic isolates of pasteurella multocida representing capsular types a and d were evaluated. expression of proteins, in particular, outer membrane proteins and iron-regulated proteins, was not affected by exposure of bacterial cells to low concentrations of antibiotics. however, exposition of surface antigens was m ... | 1992 | 1444290 |
| interaction between ascaris suum and pasteurella multocida in the lungs of mice. | in an experiment including 8 groups of 15 mice, the effect of migrating ascaris suum larvae in the lungs on the establishment and pathogenicity of aerosol exposure to pasteurella multocida was investigated. following aerosol exposure to p. multocida, mice with migrating a. suum in their lungs developed more severe pneumonia and septicaemia than did parasite-free mice. the parasite-induced effect on bacterial pathogenicity was more marked for a non-toxin-producing p. multocida as compared with a ... | 1992 | 1438140 |
| [pulmonary pasteurellosis in a young patient with multiple trauma]. | a case is reported of an 18-year-old male patient who had a road traffic accident, with head and chest injuries. the patient was admitted to the surgical intensive care unit 24 h later because of an alteration of his level of consciousness. he required artificial ventilation. five days later, he developed right-sided lower lobe pneumonia, treated with positive end-expiratory pressure. a gram negative organism was found on bronchial brushing, but not in haemocultures. it was identified as pasteur ... | 1992 | 1443800 |
| molecular correlates of physiological regulation in a p-type h(+)-atpase. | | 1992 | 1449060 |
| in utero infection due to pasteurella multocida. | | 1992 | 1445989 |
| pasteurella multocida septicaemia in pigs. | | 1992 | 1449460 |
| characterization and distribution of pasteurella species recovered from infected humans. | during a 3-year period, all pasteurella strains recovered at the clinical microbiological laboratory, lund, sweden, were studied biochemically with respect to their relationship to the recently described taxa of this genus. of 159 strains recovered from 146 infected humans, 95 were identified as pasteurella multocida subsp. multocida, 21 as pasteurella multocida subsp. septica, 28 as pasteurella canis, 10 as pasteurella stomatis, and 5 as pasteurella dagmatis. the homology within and between the ... | 1992 | 1452670 |
| effect of pasteurella multocida toxin on bone resorption in vitro. | pasteurella multocida toxin (pmt), which is the primary etiologic factor in the pathogenesis of progressive atrophic rhinitis in pigs, was found to stimulate bone resorption in vitro. this stimulation was observed both in cultures of murine calvaria by measuring the release of calcium and of the lysosomal enzyme beta-glucuronidase and in murine long bone cultures by measuring the release of calcium. both systems showed the same dose response curve, with the maximal effect at a concentration of 5 ... | 1992 | 1452328 |
| interconversion of grp78/bip. a novel event in the action of pasteurella multocida toxin, bombesin, and platelet-derived growth factor. | incubation of swiss 3t3 cells with [2-3h]adenine, as in other cell types, reveals the adp-ribosylation of grp78 (the 78-kda glucose-regulated protein, also known as bip, the immunoglobulin heavy chain-binding protein), a resident endoplasmic reticulum protein that assists in the processing of proteins destined for secretion or cell surface expression. here we show that pasteurella multocida toxin, a potent growth factor for cultured fibroblasts, decreased the adp-ribosylation of grp78/bip to 16 ... | 1992 | 1460024 |
| pasteurella multocida endocarditis. | human infection with pasteurella multocida is the leading cause of animal bite wound infection. life-threatening infection may occur in patients with a variety of underlying disorders and an immunocompromised state. infective endocarditis with p. multocida is very rare and only a few clinically diagnosed cases have been reported. described here is an autopsy case of a 61-year-old man with polycystic kidney disease who had p. multocida bacteremia and acute infective endocarditis with multiple bac ... | 1992 | 1462953 |
| ovine pulmonary surfactant induces killing of pasteurella haemolytica, escherichia coli, and klebsiella pneumoniae by normal serum. | pulmonary surfactant has been shown to play an increasingly important role in bacterial clearance at the alveolar surface in the lung. this study describes a bactericidal mechanism in which ovine pulmonary surfactant induces killing of pasteurella haemolytica by normal serum. to demonstrate killing, six bacterial species were incubated first with pulmonary surfactant for 60 min at 37 degrees c and then with serum for an additional 60 min at 37 degrees c. p. haemolytica type a1 strains 82-25 and ... | 1992 | 1452351 |
| [osteomyelitis from a cat bite]. | | 1992 | 1450264 |
| comparison of ascorbic acid and ascorbic acid 2-o-alpha-glucoside on the cytotoxicity and bioavailability to low density cultures of fibroblasts. | ascorbic acid 2-o-alpha-glucoside (aa-2g) is a stable ascorbate derivative which has vitamin c activity in vivo and in vitro. we studied whether aa-2g exerts a prooxidant action in cultured fibroblasts from chick embryo and human skin, as does ascorbic acid. at concentrations of 0.1-1.0 mm, ascorbic acid markedly reduced the viable cell number of low density cultures within 24 hr, whereas aa-2g had no such effect. the ascorbate cytotoxicity was dependent on the cell density at the time of its ad ... | 1992 | 1472084 |
| serological evaluation of pasteurella multocida antigens associated with protection in buffalo calves. | different antigens of pasteurella multocida carter's type 6:b including whole bacterium, antigen heated at 56 degrees c, antigen heated at 100 degrees c, sonicated antigen, capsular antigen, potassium thiocyanate extract, lipopolysaccharide and sodium salicylate extract were evaluated to assess protection in buffalo calves against haemorrhagic septicaemia. sera from calves with known protection status in experimental challenge were titrated by enzyme-linked immunosorbent assay (elisa) against al ... | 1992 | 1472736 |
| avian cholera and waterfowl biology. | | 1992 | 1474673 |
| molecular analysis of the aroa gene of pasteurella multocida and vaccine potential of a constructed aroa mutant. | the aroa gene from pasteurella multocida was cloned by complementation of the escherichia coli aroa mutant ab2829 with a dna library constructed in puc18. the nucleotide sequence of the p. multocida aroa gene indicated an open reading frame encoding a protein of 441 amino acids, which showed a high degree of homology with the amino acid sequences of various other bacterial aroa proteins. the cloned p. multocida aroa gene was inactivated by insertion of a kanamycin-resistance gene and reintroduce ... | 1992 | 1474900 |
| the macrophage-activating properties of growth hormone. | 1. we compared the ability of growth hormone (gh) and a well-characterized macrophage-activating factor, interferon-gamma (ifn-gamma) to activate highly purified populations of alveolar macrophages. both gh and ifn-gamma primed macrophages triggered with opsonized zymosan to secrete superoxide anion (o2-) in vitro, but ifn-gamma was effective at a 40-fold lower concentration. antibody blocking studies demonstrated that the priming activity of gh was independent of ifn-gamma, and the activity of ... | 1992 | 1468117 |
| interaction between bordetella bronchiseptica and toxigenic pasteurella multocida on the nasal mucosa of spf piglets. | the interaction between bordetella bronchiseptica and type d toxigenic pasteurella multocida was studied in five groups of 4 specific-pathogen-free (spf) piglets each. at 28 days of age, piglets of groups 3 and 4 were inoculated into both nostrils with 10(8) colony-forming-units (cfu) of a non-dermonecrotic toxin (dnt)-producing, phase i strain of b. bronchiseptica. piglets of groups 1 and 3 were treated intranasally with a sonic extract of the non-toxic strain of b. bronchiseptica and those of ... | 1992 | 1477161 |
| the first outbreak of fowl cholera in muscovy ducks (cairina moschata) in japan. | the first outbreak of fowl cholera occurred in a flock of muscovy ducks (cairina moschata) in okinawa prefecture of japan in november 1990. fifty (25%) of 200 birds in a farm died of an acute disease. remaining birds recovered after treatment with oxytetracycline. pasteurella multocida subsp. multocida was isolated in pure culture from all tissues tested from two dead birds. serovars of the isolates were identified as carter's capsular type a. heddleston's type 3.4.12, and namioka's type 5:a whi ... | 1992 | 1477178 |
| [possibilities for the establishment of pneumonia-free swine herds by immunization and administration of cefquinome]. | the application of bordetella and pasteurella inactivated and adsorbed vaccines together with cefquinome to sows, piglets and weaners led to a significant reduction of the incidence of rhinitis atrophicans and pneumonia. the frequency of positive isolates of p. multocida, h. parasuis and a. pleuropneumoniae out of nasal swabs was reduced during the treatment. | 1992 | 1471972 |
| use of elisa to detect toxigenic pasteurella multocida in atrophic rhinitis in swine. | the use of an enzyme-linked immunosorbent assay (elisa) as a means of detecting dermonecrotoxin-producing strains of pasteurella multocida was investigated. the assay was evaluated as a means to identify toxigenic p. multocida isolates recovered from nasal secretions of swine with atrophic rhinitis. the sensitivity and specificity of the elisa for detecting dermonecrotoxin-producing p. multocida strains were compared to those of mouse-inoculation and cytotoxicity assays. the elisa was highly sen ... | 1992 | 1457544 |
| [occurrence and drug resistance of bacteria pathogenic to the lungs from autopsy material of swine]. | eight hundred and fifty-four piglets which died or were euthanized due to pneumonia or rhinitis atrophicans, were investigated during the period of 1986-1990. of the animals, 569 showed bronchopneumonia, 218 had pleuritis, pericarditis and peritonitis, 165 had rhinitis atrophicans, 58 pleuropneumonia, and 9 animals had fibrinous pneumonia. pasteurella multocida, haemophilus parasuis, bordetella bronchiseptica, actinobacillus pleuropneumoniae and pasteurella haemolytica were isolated in 59.1%, 29 ... | 1992 | 1481214 |
| vaccination of turkeys with cell-free culture filtrate of pasteurella multocida: effects of dilution, iron chelation, and heterologous challenge. | two experiments were done to further define cell-free culture filtrate (ccf) from pasteurella multocida and its endotoxin content in protecting turkeys against challenge. in the first experiment, the greater-than-30,000-molecular-weight fraction of p. multocida strain r44/6 (serotype 3/4/9/12) ccf was used in 10-fold dilutions given by air-sac inoculation or aerosol to vaccinate turkeys, which were subsequently challenged with either homologous (p-1059, serotype 3) or heterologous (x-73, serotyp ... | 1992 | 1485881 |
| turkey macrophage and heterophil bactericidal activity against pasteurella multocida. | bactericidal activity of turkey macrophages and heterophils was demonstrated in an in vitro colorimetric bactericidal assay. two vaccine strains and one field isolate of pasteurella multocida a:3,4 and a single isolate each of escherichia coli and staphylococcus aureus were compared for susceptibility to the bactericidal activity of turkey macrophages and heterophils. only p. multocida a:3,4-strain m-9 (the least virulent strain) was susceptible to macrophage bactericidal activity in the absence ... | 1992 | 1485882 |
| pharmacokinetic evaluation of ceftiofur in serum, tissue chamber fluid and bronchial secretions from healthy beef-bred calves. | ceftiofur is a new broad spectrum cephalosporin marketed for the treatment of acute bovine respiratory disease. in this investigation ceftiofur was administered by intramuscular injection, at 24 h intervals, to healthy beef-bred calves for four days at dosages of 2.2 and 4.4 mg/kg of body weight, with 4 wk intervals between dosing regimens. serum, tissue chamber fluid (tcf), and bronchial secretion (bs) concentrations of ceftiofur were measured by microbiological assay after the first and fourth ... | 1992 | 1477795 |
| factors affecting the strength of flexor tendon repair. | the effects of different thicknesses and configurations of core sutures were studied in human cadaveric flexor tendon repairs. both straight and cyclic load tests were employed. to exploit the full strength of 4/0 suture material, the kessler repair using four locked single knots would seem to be appropriate. | 1992 | 1479249 |
| some aspects of the epidemiology and control of salmonella typhimurium infection in outwintered suckler cows. | two outbreaks of salmonella typhimurium infections affected outwintered, spring-calving suckler cows in late pregnancy. the infections spread rapidly both within and between groups of stock on the affected farms, with morbidity in the infected groups varying from 14.5 per cent to over 60 per cent, and mortality in adult cattle varying from 0 to 14.3 per cent. prophylactic measures included the use of antibiotics and killed vaccines against escherichia coli, salmonella dublin, s typhimurium, and ... | 1992 | 1475896 |
| avoidance of endotoxin-induced inflammation during studies of albumin clearance from caprine joints. | intra-articular injection of radiolabelled, commercial goat serum albumin (gsa) produces acute arthritis in caprine joints. this inflammation distorts clearance values and vitiates studies of normal lymphatic function. endotoxin, routinely found in commercial albumin preparations, appears to cause this local reaction. we describe a simple method for the preparation of low-endotoxin, radioiodinated serum albumin from aseptically collected serum. we have used this technique to prepare gsa for use ... | 1992 | 1489542 |
| evaluation of an atrophic rhinitis vaccine under controlled conditions. | a vaccine containing inactivated cultures of bordetella bronchiseptica, toxigenic pasteurella multocida type d and dermonecrotic p multocida type d toxoid in an oil-in-water adjuvant was given to seven sows, with seven others acting as controls. half the piglets in each litter were exposed intranasally when four days old to b bronchiseptica and when eight days old to toxigenic p multocida type d. there was considerably less sneezing in the litters of the vaccinated sows and when the piglets were ... | 1992 | 1496755 |
| factors affecting endotoxin release from the cell surface of avian strains of pasteurella multocida. | two avian strains of pasteurella multocida, a vaccine strain and a virulent field isolate, were investigated to determine their propensity to release endotoxin from the cell surface. both organisms released comparable amounts of endotoxin when plasma complement proteins were present, however the virulent strain did so without the loss of viability that occurred in the vaccine strain. blocking complement activity decreased the ability of plasma to elicit endotoxin release from the bacteria. when ... | 1992 | 1496810 |
| [oligoarthritis and bursitis caused by pasteurella multocida secondary to a cat scratch]. | | 1992 | 1489806 |
| characteristics of pasteurella multocida isolated from humans, swine and poultry in thailand. | pasteurella multocida is a pathogen of animals and humans. most of the patients have been associated with animals but many cases had not contacted them. the failure to diagnose p. multocida infections is mostly due to misidentification on gram stained smears and inadequate laboratory identification techniques. in order to compile detailed characteristics of the organism we studied the physical and biochemical properties of 70 isolates of p. multocida - 17 human, 23 swine and 30 poultry. all isol ... | 1992 | 1488711 |
| polymyxin b: pharmacokinetics of single doses given intravenously and intramuscularly to turkeys, and minimal inhibitory concentrations for escherichia coli and pasteurella multocida. | the 50% and 90% minimal inhibitory concentrations (mic50 and mic90) of polymyxin b for avian escherichia coli and pasteurella multocida isolates were determined by the agar plate dilution method. polymyxin b at approximate mic level in serum was bactericidal for e. coli in 2 to 4 hours. aqueous polymyxin b sulfate was administered by a single bolus intravenous injection into turkeys at 10,000 iu/kg, and by a single bolus intramuscular injection at 5,000, 10,000 or 20,000 iu/kg. effective serum d ... | 1992 | 1492521 |
| chronic frontal sinusitis in dairy cattle: 12 cases (1978-1989). | chronic frontal sinusitis in 12 dairy cattle most often was associated with a history of dehorning, in which the sinus was entered (67%), or with respiratory tract disease (25%). the most common organisms isolated were actinomyces pyogenes and pasteurella multocida. signs of infection did not develop for months in some cattle and were often intermittent. the most common clinical signs included anorexia, lethargy, fever, frontal bone distortion, exophthalmos, abnormal posture, nasal discharge, an ... | 1992 | 1500335 |
| passive protection of mice with antiserum to neuraminidase from pasteurella multocida serotype a:3. | antiserum to a partially purified neuraminidase from pasteurella multocida, type a:3, was adsorbed with protease-digested p. multocida type 3 lipopolysaccharide (lps) to remove lps immunoreactivity. the lps-adsorbed antineuraminidase caused a 77% reduction in the neuraminidase activity of homologous p. multocida in an in vitro enzyme neutralization test. all 14 mice passively immunized with the adsorbed antineuraminidase were protected against challenge infection with homologous p. multocida in ... | 1992 | 1496818 |
| serologic survey for selected arboviruses and other potential pathogens in wildlife from mexico. | during 1988 and 1989, a serologic survey of wildlife was conducted in northeastern mexico to determine the presence, prevalence, and distribution of arboviruses and other selected disease agents. eighty mammal specimens were tested. antibodies to vesicular stomatitis-indiana, venezuelan equine encephalitis-mena ii, rio grande virus, and vesicular stomatitis-new jersey were detected predominantly in small mammals. deer and mouflon (ovis musimon) had antibodies to bluetongue and epizootic hemorrha ... | 1992 | 1512876 |
| polypeptides associated with pasteurella multocida infection in rabbits. | polypeptides from whole cell preparations of pasteurella multocida serotypes a:12 and a:3 were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and transferred to nitrocellulose paper. antigens were detected by immunoblot analysis, using sera from 3 groups of rabbits. sera were obtained from rabbits inoculated intranasally with p multocida serotype a:12 or a:3, from rabbits maintained in a rabbitry with enzootic p multocida a:12 infection, and from rabbits maintained in a r ... | 1992 | 1497178 |
| long-term study of aerobic bacteria of the genital tract in breeding bitches. | the aerobic bacterial flora of the genital tract was characterized in 59 bitches in an 18-month study. the bitches represented 4 breeds and were from 3 kennels. collection of vaginal swab specimens for bacterial culturing was performed every month, except during estrus when specimens were collected every week (n = 826). the capsule of the swab containing transport media was broken before specimen collection to moisten the tip, which helped to reduce the number of negative cultures. all bitches h ... | 1992 | 1524290 |
| long-term study of aerobic bacteria of the genital tract in stud dogs. | the aerobic bacterial flora of the genital tract was characterized in 15 stud dogs in an 18-month study. the dogs represented 4 breeds and were from 3 kennels. bacterial samples from the prepuce and semen were collected every month, except in connection with matings, when they were collected weekly (464 samples). the dogs that were included all mated at least once during the study. the mean pregnancy rate, litter size, and pup mortality for the bitches with which they had mated were all within n ... | 1992 | 1524291 |
| [the importance of dermonecrotoxin and dermonecrotoxoid of pasteurella multocida for the calf]. | the i. m. application of dermonecrotoxin of p. multocida var. d led to an atrophy of nasal conchae, liver-swelling and to induration of liver and spleen. the intratracheal application caused a lobular pneumonia. the vaccination with toxoid resulted in an immunity against a challenge with toxin but not with p. multocida var. d. correlations between antitoxic serum-titers and immunity have to be investigated in future. | 1992 | 1497586 |
| a pathologic and bacteriologic study on otitis media in swine. | a pathologic and bacteriologic study on otitis media in swine was performed on 237 swine, ranging in age from 1 day to 1 year. these 237 swine from eight selected farms were slaughtered due to unfavorable prognosis associated with clinical signs of illness. one hundred sixty-three (68.8%) of the 237 swine were found to be affected with otitis, though only a few swine showed clinical signs characteristic of the disease. one hundred fifty-one (63.7%), 53 (22.4%), and 39 (16.5%) had lesions in the ... | 1992 | 1514220 |
| [clinicobacteriological study of pasteurella multocida infection as a zoonosis. (2)--comparisons of p. multocida separated from patients and their pet dogs and cats]. | a total of 17 strains of pasteurella multocida, of which 13 were isolated from patients treated at nihon university itabashi hospital or nihon university surugadai hospital between april, 1984 and march, 1991 and 4 from 1 dog and 3 cats kept by the patients, were evaluated with respect to their biochemical properties, sensitivity to drugs, and serotype. the isolated strains were all considered to be pasteurella multocida subsp. multocida because of the agreement of their responses to indole, sor ... | 1992 | 1507482 |
| pulp reactions to resin cements. | several formulas of a resin-filled cement that successfully passed a series of laboratory tests were evaluated for their pulp reactions in primates. their performance was compared to three controls: a positive control (silicate cement), a negative control (zinc oxide-eugenol) and a control group with the protection of calcium hydroxide. the chemical cure resin cement scored the lowest reactions for the 5-day evaluation. the intermediate and prolonged periods demonstrated no significant differenc ... | 1992 | 1524752 |
| pasteurella multocida septicaemia in two calves. | | 1992 | 1530558 |
| effects of cardioplegic solutions and their components on human saphenous vein contractility. | cardioplegic solution administration into the vein graft is an established method to ensure cardioplegic distribution beyond coronary artery stenoses. the ultrastructural demonstration of severe endothelial damage after cardioplegic exposure suggests that intravenous cardioplegic administration can contribute to early and late graft thrombosis. the direct effect on human saphenous vein contractility of three cardioplegic solutions and their components was compared. a solution with 30 mmol/l k+ a ... | 1992 | 1540064 |
| isolation of p multocida f-3, 4 from a stillborn snow leopard. | | 1992 | 1542981 |
| [pasteurella multocida infection following injury by an inert material]. | | 1992 | 1531266 |
| polymorphism in the rd (d6s45) gene. | the rd (d6s45) gene in the class iii region of the hla major histocompatibility complex encodes a protein normally containing 24 consecutive basic-acidic dipeptide repeats. we determined the frequency of variations in the number of repeats by use of the polymerase chain reaction. of 107 subjects 7 (3.3%) carried genes encoding 22 or 23 repeats. there was no difference in the frequency of such polymorphisms between normal individuals and those with systemic lupus erythematosus, a disease associat ... | 1992 | 1534063 |
| fowl cholera epornitic: antigenic characterization and virulence of selected pasteurella multocida isolates. | an epornitic of fowl cholera involving turkey flocks of several farms within a 15-mile radius in utah was studied. pasteurella multocida strains isolated from birds in affected flocks were antigenically characterized as a:1, a:3, and b:4, based on capsular sero-grouping and somatic serotyping results. experimental exposure of poults with each of two strains representing the rarely reported capsular group b indicated that both were virulent. | 1992 | 1533118 |
| in utero infection due to pasteurella multocida in the first trimester of pregnancy: case report and review. | to our knowledge, we report the first case of in utero infection in humans due to pasteurella multocida in the first trimester of pregnancy. after antibiotic therapy was initiated, the mother recovered rapidly from bacteremia but the fetus was spontaneously aborted. pathological examination of the fetus and placenta revealed acute deciduitis and chorionitis, indicating an infectious etiology for the abortion. the clinical and pathological features of this case are compared with those of the five ... | 1992 | 1554837 |
| heat shock decreases nuclear transport of 3,5,3'-triiodo-l-thyronine in clone 9 cells. | thyroid hormone, t3, enters cells through an energy-dependent, saturable process and/or passive diffusion. although the nucleus is the primary site of t3 action, exact mechanisms by which t3 is transported to nucleus are uncertain. in this report, initial cellular and nuclear uptake of t3 was determined using a rat liver cell line (clone 9), in which energy-dependent cellular t3 uptake was demonstrable. one to 5 mm sodium butyrate enhanced cellular t3 uptake with a concomitant increase in nuclea ... | 1992 | 1547743 |
| phylogeny of 54 representative strains of species in the family pasteurellaceae as determined by comparison of 16s rrna sequences. | virtually complete 16s rrna sequences were determined for 54 representative strains of species in the family pasteurellaceae. of these strains, 15 were pasteurella, 16 were actinobacillus, and 23 were haemophilus. a phylogenetic tree was constructed based on sequence similarity, using the neighbor-joining method. fifty-three of the strains fell within four large clusters. the first cluster included the type strains of haemophilus influenzae, h. aegyptius, h. aphrophilus, h. haemolyticus, h. para ... | 1992 | 1548238 |
| septic arthritis due to pasteurella multocida. | we have reported two cases of septic arthritis caused by pasteurella multocida, the first, septic polyarthritis unrelated to animal contact and the other, septic monarthritis after a cat scratch. serious infections with this gram-negative bacillus must be treated with intravenous penicillin, ampicillin, or a third-generation cephalosporin; aminoglycosides are not effective. a high index of suspicion is appropriate when there is a history of a recent animal-inflicted wound, though infection may a ... | 1992 | 1546361 |
| conditions for transformation of pasteurella multocida by electroporation. | conditions for electroporation of plasmid dna into pasteurella multocida were determined for use in developing a cloning system to study virulence factors of p. multocida. the highest efficiency of transformation (1.25 x 10(7) cfu/micrograms dna) was obtained when 7.6 x 10(10) cells of p. multocida strain r473 were electroporated at 12.5 kv/cm (10 ms, 5 ng of pvm109). transformation efficiencies of cells prepared at mid-log-phase were approximately 0.5 log10 lower than early, late, or stationary ... | 1992 | 1560754 |
| 11 beta-amidoalkyl estradiols, a new series of pure antiestrogens. | in order to find new antiestrogens, devoid of any agonistic activity, a series of 11 beta-amidoalkyl estradiols were prepared. these compounds have been studied in comparison with tamoxifen (tam): in vitro, for their relative binding affinities (rba) for mouse and mcf-7 estrogen receptors (er) and for their antiproliferative effect on mcf-7 (estradiol or egf/pdgf stimulated) and ly2 human breast cancer cell lines; in vivo, for their uterotrophic/antiuterotrophic activities in the mouse and for t ... | 1992 | 1562531 |
| bite wounds and infection. | one of every two americans will be bitten by an animal or by another person at some point. bites account for approximately 1% of all visits to emergency rooms; injuries inflicted by dogs are most common. the bacteria involved in infection of bite wounds include pasteurella multocida, staphylococcus aureus, staphylococcus intermedius, alpha-hemolytic streptococci, capnocytophaga canimorsus, and other members of the oral flora. anaerobic bacteria are present in approximately one-third of bite woun ... | 1992 | 1562653 |
| [detection of the nucleolar activity in alveolar macrophages of swine]. | with the help of the toluidine blue-staining-technique different characteristic shapes of alveolar macrophage nucleoli were detected, indicating differences in the rrna synthesis activity of these cells. after application of a pasteurella multocida aerosol the percentage of alveolar macrophages with a high rrna synthesis increased. no correlation between the nucleolar activity and the efficacy of the clearance of aerogenously administered pasteurella could be measured. | 1992 | 1559462 |
| cloning system for candida glabrata using elements from the metallothionein-iia-encoding gene that confer autonomous replication. | the yeast candida glabrata harbors two distinct gene families that encode metallothioneins (mts). one of these loci, the mt-iia locus, exhibits selective and tandem amplification in many wild type strains of c. glabrata. the present paper demonstrates that the amplified mt-iia gene contains autonomously replicating sequences (ars). these ars elements have been used to construct vectors capable of replicating in c. glabrata. the ars element(s) in the mt-iia gene were localized to a 457-bp segment ... | 1992 | 1563627 |
| treatment of pasteurella multocida cellulitis with ciprofloxacin. | | 1992 | 1569315 |
| survival of toxigenic pasteurella multocida in aerosols and aqueous liquids. | the survival of toxigenic pasteurella multocida in air and liquids was studied to identify possible risk factors in the etiology of atrophic rhinitis. in aerosols, at low relative humidity (28%), the viability of toxigenic p. multocida 5 min after aerosolization was at least 22% of its initial value. viability at low relative humidity declined to 8% after 45 min. viability at high relative humidity (79%) was 69% after 5 min and declined to 2% after 45 min. survival of toxigenic p. multocida in l ... | 1992 | 1575496 |
| pasteurella multocida toxin. the characterisation of the toxin and its significance in the diagnosis and prevention of progressive atrophic rhinitis in pigs. | | 1992 | 1576005 |
| cloning and sequence determination of a cdna encoding aspergillus nidulans calmodulin-dependent multifunctional protein kinase. | a partial cdna encoding aspergillus nidulans calmodulin-dependent multifunctional protein kinase (acmpk) was isolated from a lambda zap expression library by immunoselection using monospecific polyclonal antibodies to the enzyme. the sequence of both strands of the cdna (cmka) was determined. the deduced amino acid (aa) sequence contained all eleven consensus domains found in serine/threonine protein kinases [hanks et al., science 241 (1988) 42-52], as well as a putative calmodulin-binding domai ... | 1992 | 1563634 |
| bacteremia due to pasteurella multocida. | pasteurella multocida should be considered as a possible etiologic agent in any infection that is the result of an animal bite or scratch. because of its opportunistic capability, it should be included among the possible pathogens in bacteremia, particularly in any patient with immunosuppression or liver cirrhosis, especially if there is a history of animal exposure. | 1992 | 1566154 |
| haemorrhagic septicaemia--a general review. | | 1992 | 1576525 |
| further investigations on pasteurella multocida infections in feral birds injured by cats. | a total of 64 pasteurella multocida strains (46 out of 11 different feral bird species, partly injured by cat bites, and 18 strains originating from clinically healthy cats) were biochemically differentiated. as a result, 67.4% of the strains from feral birds and 61.1% from the cats were classified as the subspecies multocida, whilst 21.7% and 27.8% were identified as the subspecies septica. the percentage of frequency for both the subspecies was of a comparable order of magnitude from the birds ... | 1992 | 1580104 |
| pasteurella multocida toxin is a potent inducer of anchorage-independent cell growth. | the growth of many normal cells requires contact with an adhesive substratum, a requirement that is frequently abrogated in the transformed phenotype. we have explored pathways that can lead to the anchorage-independent growth of cultured rat-1 fibroblasts. pasteurella multocida toxin (pmt), a 146-kda mitogenic protein, caused a striking increase in the formation of colonies (greater than 200 microns) from single cells in soft agar. the magnitude of the effect of pmt was greater than that achiev ... | 1992 | 1584759 |
| characterization of the inhibition of interleukin 2 mrna accumulation by 12-o-tetradecanoylphorbol-13-acetate in primary lymphocytes. | we found previously that bovine lymph node cells (lnc) incubated with 12-o-tetradecanoylphorbol-13-acetate (tpa) for 18 h proliferate only to a limited degree on subsequent stimulation with concanavalin a (con a), or with the comitogenic combination of con a plus tpa. the lack of proliferation was traced to a lack of secretion of interleukin 2 (il-2). lack of secretion was paralleled by a decrease in il-2 mrna levels. in this study we further characterized how tpa pretreatment affected il-2 mrna ... | 1992 | 1576243 |
| cell surface characteristics and virulence in mice of pasteurella multocida. | the virulence of three avian strains of pasteurella multocida was evaluated in mice. strains p-1059i (serotype a:3) and its uncapsulated variant p-1059b and strain 2723 (serotype a:16) were compared. capsular material thickness after polycationic ferritin labelling of dextrose starch agar (dsa)-grown p. multocida was shown to vary with the strain and was not always related to virulence. addition of alpha,alpha' bipyridyl (bip) (160 microm) to the culture medium did not affect capsule production ... | 1992 | 1576405 |
| comparative susceptibility of caponized and uncaponized tom turkeys to pasteurella multocida. | when susceptibility to virulent pasteurella multocida was compared, there was no significant (p greater than 0.05) difference between caponized and uncaponized tom turkeys. neither was there any significant (p greater than 0.05) difference between the surviving caponized and uncaponized toms in the development of serum anti-p. multocida antibody. however, at 28 weeks of age, the average live body weight of the caponized toms was significantly (p less than 0.05) lower than that of the uncaponized ... | 1992 | 1567314 |
| cytological findings in bronchoalveolar lavage fluid from feedlot calves: associations with pulmonary microbial flora. | samples obtained by bronchoalveolar lavage (bal) were used to evaluate pulmonary cytology in 59 feedlot calves with clinical signs of respiratory disease (cases) and 60 clinically normal comparison calves (controls). many calves in both case and control groups had inflammatory changes in the lower respiratory tract, as determined by changes in proportions in the bal differential cell count. approximately 35% of cases and 40% of controls showed a normal differential cell count. it therefore appea ... | 1992 | 1591654 |
| serological characterisation of pasteurella multocida strains isolated from wild ruminants as capsular serogroup b. | | 1992 | 1595164 |
| intracerebroventricular immunization with trh-antiserum lowers blood pressure in spontaneously hypertensive rats. | centrally administered thyrotropin-releasing hormone exerts a well documented hypertensive effect. in this study, the possible physiological role of thyrotropin-releasing hormone in the central cardiovascular regulation was evaluated in spontaneously hypertensive rats receiving long-term (8-14 days) intracerebroventricular infusion of a heterologous antiserum to thyrotropin-releasing hormone. the effect of this passive immunization on the blood pressure was monitored from conscious animals by th ... | 1992 | 1595355 |
| [the ionized calcium in the blood of domestic chickens: dependence on age and sex]. | in the present study concentration of ionized calcium and the correlation between total and ionized calcium in blood of domestic fowl and its dependence on age and sex were investigated. furthermore a possible influence of blood sampling procedure on the measured values was assessed. leghorn chickens of either sex, aged 3, 9, 25, and 80 weeks, respectively, were used. blood sampling was performed by vein-puncture and indwelling catheters, respectively, of both ulnaris vein and artery of animals ... | 1992 | 1590033 |
| crossmodal changes in the somatosensory vibrissa/barrel system of visually deprived animals. | cats deprived of vision from birth adapt remarkably well to their situation and show little behavioral impairment. they seem to compensate for their lack of vision by relying more on their auditory and tactile senses. we report here that the facial vibrissae, which are most important for tactile orientation in many animals, show supernormal growth in both cats and mice that have been deprived of vision from birth. furthermore, the whisker representation in the somatosensory cortical barrel field ... | 1992 | 1594614 |
| estimating the stage-specific numbers of hiv infection using a markov model and back-calculation. | the back-calculation method has been used to estimate the number of hiv infections from aids incidence data in a particular population. we present an extension of back calculation that provides estimates of the numbers of hiv infectives in different stages of infection. we model the staging process with a time-dependent markov process that partitions the hiv infectious period into the following progressive stages and/or substages: stage 1, infected but antibody negative; substages 2-3; antibody ... | 1992 | 1594820 |
| hyaluronic acid and a (1----4)-beta-d-xylan, extracellular polysaccharides of pasteurella multocida (carter type a) strain 880. | | 1992 | 1596931 |
| brefeldin a enhances receptor-mediated transcytosis of transferrin in filter-grown madin-darby canine kidney cells. | the effects of brefeldin a (bfa) on transferrin (tf) transcellular transport, tf receptor (tfr) distribution, and tfr-mediated endocytosis in filter-grown madin-darby canine kidney (mdck) cells were studied. bfa (1.6 micrograms/ml) markedly enhanced the transcytosis of 125i-labeled tf (125i-tf) in both apical-to-basal and basal-to-apical directions; yet, bfa did not enhance the transcytosis of either native horseradish peroxidase (hrp) or membrane-bound hrp-poly(l-lysine) conjugates. furthermore ... | 1992 | 1618847 |
| pasteurella infection in a total knee arthroplasty. | hematogenous infection of a total joint arthroplasty is a serious complication that has well-known etiologies. one of the most unusual inciting events is a bite wound. pasteurella multocida is an anaerobic organism found in the mouths of mammals that has rarely been found to infect total knee arthroplasties. prompt recognition of such an infection and prophylactic treatment with a penicillinase-resistant penicillin should maximize the patient's opportunity to eradicate such an infection. | 1992 | 1603610 |
| characterization of pasteurella multocida from nasal cavities of piglets from farms with or without atrophic rhinitis. | a total of 137 strains of pasteurella multocida isolated from the nasal tracts of pigs with and without clinical atrophic rhinitis (ar) were studied for their biochemical, antigenic, and toxigenic characteristics. there were no major biochemical differences among the p. multocida isolates. capsular antigen types a and d were both present in the nasal cavities of the pigs with or without clinical ar. however, the prevalence of type d was higher on farms with pigs with ar. types a and d with diffe ... | 1992 | 1624554 |
| pasteurella multocida infection after a tasmanian devil bite. | | 1992 | 1623089 |
| [purification, amino acid composition and n-terminal sequence of the major protein (protein h) of the outer membrane of pasteurella multocida]. | the major protein (protein h) of the outer membrane of pasteurella multocida was purified by size-exclusion chromatography after selective extraction with detergents. the protein forms homotrimers which are stable in the presence of sds at room temperature. upon treatment at 100 degrees c, the protein is fully dissociated by the detergent into monomers exhibiting an apparent molecular mass of 37 kda as estimated by electrophoresis. the amino acid composition of protein h is characterized by a lo ... | 1992 | 1606514 |
| pasteurella multocida infection in total knee arthroplasty. case report and literature review. | pasteurella multocida, a small gram-negative bacterium, is part of the normal mouth flora of many animals, including domestic cats and dogs. while commonly associated with infections in animals, it is a rare cause of human disease. the majority of pasteurella infections in humans occur with percutaneous inoculation of the organism following a bite by a cat or dog, although disease without antecedent animal exposure or with causal animal contact does occur. the spectrum of disease produced ranges ... | 1992 | 1613522 |
| vaccine efficacy for reducing turbinate atrophy and improving growth rate in piggeries with endemic atrophic rhinitis. | two vaccines, based on formalin-killed whole cells of toxigenic pasteurella multocida type d and bordetella bronchiseptica combined with a partially toxoided cell extract of p multocida, were prepared with freund's incomplete adjuvant (vaccine 1) or by alum precipitation (vaccine 2). each was tested for safety and efficacy in reducing the severity of nasal turbinate atrophy and improving the growth rate of pigs in three western australian commercial piggeries with endemic atrophic rhinitis. in s ... | 1992 | 1627085 |