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[problems in the use of radioactively labelled bacteria in experiments. 2. quantitative method for the evaluation of pathogens in the calf lung by means of labelled bacteria after aerosol or intratracheal administration].by means of two aerosol apparatures radioactive labelled pasteurella-multocida-germs were given to calves via a respiratory mask. labelling of pasteurellae was done internal by using special nutritive media with fe-59 or p-32. in a period of 10-25 minutes 5 x 10(9)-10(10) labelled bacteria were given to the animals for inhalation. another animal group was injected intratrachealy with the same quantity of labelled germs. immediately after termination of germ application the animals were killed an ...1977603372
identification of a new allele of es-i segregating in an inbred strain of mice.a new allele of es-1, designated es-1e, has been identified in the mouse. this allele was discovered segregating among the progeny of a strain dba/2j male and is apparently the result of a spontaneous mutation within this strain. genetic analyses have shown that this mutation is heritable and, further, that both heterozygous and homozygous progeny are viable and fertile. to date, no discernible deleterious effects have been identified as associated with this mutation.1979540008
the response of turkeys to varying doses of live oral pasteurella multocida vaccine.groups of 30 turkeys were vaccinated by the drinking water route against fowl cholera with varying doses of the low virulence, cu strain, of pasteurella mulocida. one group (heavy dose) received 1.2 x 107, another (medium dose) 1.5 x 105, and a third (light dose) 1.0 x 103 bacteria per ml. of drinking water. two (6.7%) vaccine induced cholera deaths occurred in the heavy dose group. no deaths resulted in the other groups. maximum serum antibody titers per group were; light dose 1:32, medium dose ...1977605007
an evaluation of the effect of various concentrations of the clemson university pasteurella multocida drinking water vaccine on the immune response against fowl cholera disease in turkey. 1977605013
pasteurella multocida infection of broiler chickens. 1978716191
a case of clinical mastitis due to pasteurella multocida. 1978716192
evaluation of rofenaid and a commercial bacterin for prevention of cranial form of fowl cholera in turkeys.rofenaid, a potentiated sulfadimethoxine at drug concentrations of 0.04, 0.02, and 0.01% in feed, a combination of vaccination with a commercial bacterin and 0.01% potentiated sulfadimethoxine (rofenaid), and vaccination separately, significantly (p less than 0.05) increased livability of turkeys experimentally induced with the cranial form of fowl cholera as compared to that of the nonmedicated nonvaccinated exposed turkeys. turkeys were exposed by the administration of pasteurella multocida (i ...1977605073
growth curves and stabilization of fresh vaccine cultures of the clemson university strain of pastuerella multocida.growth curves at 37 c for the clemson university strain of pasteurella multocida were about the same in either brain-heart-infusion broth or in a recently developed broth called "special broth tv". counts in both broths were usually greater than 1 x 10(9) viable bacteria per ml. with the addition of 5 g of dried skim milk to each 100 ml of broth culture in the stationary phase of the growth curve, only a slight decrease in viable counts occurred over the next 7 to 14 days when held at 4 c. such ...1978674040
[growth of some pathogenic microorganisms on chemically defined media which were proposed for sensitivity testing (author's transl)].the growth of 16 bacterial cultures, which belong to the frequently encountered pathogens, in three different chemically defined fluid media was investigated through turbidity measurements in comparison with mueller-hinton-broth. e. coli, salm. dublin, salm. typhi-murium, enterobacter cloacae, proteus mirabilis, pseud. aeruginosa and bac. cereus grew in two of the three tested defined media with approximately the same intensity as in the mueller-hinton broth. staph. aureus grew well only in one ...1978730218
pharmacokinetics of penicillin g in the turkey.parmacokinetics of penicillin g was determined for the turkey. the study was prompted by the isolation of a sulfonamide-resistant strain of pasteurella multocida from tissues of turkeys involved in an outbreak of fowl cholera and the subsequent discovery that little pharmacologic information was available concerning other antimicrobial agents in that species. penicillin g was chosen for study because p multocida is susceptible to this antibiotic. the elimination of the antibiotic followed first- ...1978677541
identification of a new allele of es-i segregating in an inbred strain of mice.a new allele of es-1, designated es-1e, has been identified in the mouse. this allele was discovered segregating among the progeny of a strain dba/2j male and is apparently the result of a spontaneous mutation within this strain. genetic analyses have shown that this mutation is heritable and, further, that both heterozygous and homozygous progeny are viable and fertile. to date, no discernible deleterious effects have been identified as associated with this mutation.1979540008
fowl cholera: immunization of chickens with potassium thiocyanate (kscn) extract of pasteurella multocida serotype 3.potassium thiocyanate (kscn) extract of pasteurella multocida, serotype 3, was found to be immunogenic against a challenge infection of homologous as well as one heterologous strain tested (serotype 1). ouchterlony's gel-diffusion analysis revealed the presence of two components in the kscn-extracts of both serotypes 3 and 1, which were antigenically identical.1977606217
a case report of total knee arthroplasty infected by pasteurella multocida.a 72-year-old woman with a total knee prosthesis was infected with pasteurella multocida organisms from a cat bite. the joint was successfully salvaged by surgical debridement, closed tube irrigation utilizing .25% acetic acid and appropriate antibiotics.1978679534
characterization of a pasteurella multocida bacteriophage.the pasteurella multocida bacteriophage b939a produces turbid plaques, which suggests infection with a temperate phage. attempts to induce production of lytic phage by uv irradiation were unsuccessful, however, bateriophage b932a is highly stable at 4 c and relatively stable at room temperature. it tolerates moist heat at 60 c, but is inactivated at 70 c in 10 minutes. morphologically, it is a tailed phage with a hexagonal head.1978697170
[contamination and age as factors in the pathogenesis of atrophic rhinitis (author's transl)].the relationship between contamination with bordetella bronchiseptica or pasteurella multocida and the age of the piglets on the one hand and the pathogenesis of atrophic rhinitis on the other, is discussed. minimal disease-free piglets born and reared on farms on which pigs affected with clinical atrophic rhinitis were present, developed clinical atrophic rhinitis at the age of six weeks. piglets born in the central veterinary institute (cvi) of sows from herds including pigs affected with atro ...1978684734
isopycnic characterization of lipopolysaccharides from pasteurella multocida. 1978629385
pasteurella multocida infectious arthritis.pasteurella multocida, a small gram-negative rod, is a domestic animal saprophyte that occasionally causes disease in humans. infectious arthritis may develop from a superficial animal bite or scratch. nine previous cases of infectious arthritis due to this organism have been documented in the literature, and a tenth case is reported here. most patients had recent animal exposure, and half the patients had underlying chronic rheumatoid arthritis. clinical signs of inflammation were consistently ...1978686043
pasteurella multocida brain abscess following perforating cranial dog bite. 1978633019
an agglutination test for the detection of bordetella bronchiseptica infection in swine.an agglutination test with the use of formalin-killed antigen of the cell carrying the capsule was developed and used for the detection of antibody in swine naturally infected with bordetella bronchiseptica. under optimum antigen concentration and reaction temperature 210 or 60% of 342 serum samples tested from 42 conventional swine herds were positive for bordetella infection. in contrast, only 34 or 10% of 342 nasal swabs from the same animals were positive for bordetella by culture technique. ...1978688071
observation on the bacterial population of the os cervix of the ewe before and after embryo death.bacterial samples were isolated from the os cervix of mature merino ewes during a normal oestrous cycle and after colchicine treatment which killed the 25-day old embryos. the population of bacteria was small during the oestrous cycle and consisted of achromobacter spp. alcaligenes spp, corynebacterium spp, bacillus spp and escherichia coli. there was a significant increase in the numbers of bacteria isolated and a change in the proportions of the bacteria isolated from ewes after embryo death. ...1977612334
hazards of disease transfer from marine mammals to land mammals: review and recent findings.in a 5-year study (1972-1977) of microbial agents isolated from both clinically normal and diseased marine mammals, it was shown that certain disease agents are widespread in a diversity of ocean populations and that some are also transmissible to a number of terrestrial mammal species. leptospira interrogans serovar pomona has been isolated repeatedly from 2 species of pinnipeds (zalophus californianus califonianus and callorhinus ursinus). some of the more important bacterial pathogens for lan ...1978738931
live streptomycin-dependent pasteurella multocida vaccine for the prevention of hemorrhagic septicemia.a type b pasteurella multocida was used for the development of a streptomycin-dependent (strd) vaccine. pasteurella multocida r-473, a hemorrhagic septicemia strain, was mutagenized with n-methyl-n'-nitro-n-nitrosoguanidine to increase the likelihood of encountering a strd mutant and was plated on agar containing 400 microgram of streptomycin/ml. replica plating was used to differentiate dependent from resistant colonies. mice and rabbits were vaccinated with a strd mutant and 21 days later, wer ...1978697163
a case of septicemia and meningitis in an infant due to pasteurella multocida. 1978641644
response of young chickens and turkeys to virulent and avirulent pasteurella multocida administered by various routes.groups of 20 young chickens and turkeys obtained from commercial flocks and placed in pens with pine shavings over concrete floors or from the hatchery and grown on wire, were exposed to avirulent pasteurella multocida serotype 3,4 cross or virulent p. multocida serotype 3 by drinking water, ocular, subcutaneous, intracutaneous, or palatine cleft routes. a secondary exposure to virulent p. multocida serotype 1 by the palatine cleft route was given 14 days later, except that birds exposed by pala ...1978646754
a new serotype of pasteurella multocida associated with fowl cholera.gel-diffusion precipitin tests demonstrated an additional pasteurella multocida serotype, designated serotype 16. isolate p-2723, antigenically distinct from the other (previously reported) 15 serotypes, was from a turkey affected with fowl cholera. this serotype is not widely distributed. isolate p-2723 was of mild virulence in turkeys, resulting in local infections in the hock joint and sternal bursa of only 1 of 9 turkeys exposed.1978646758
[nitrofurantoin-test for the differentiation of bordetella bronchiseptica (author's transl)].bordetella bronchiseptica is primarily resistant against nitrofurantoin (mic greater than 200 mug/ml), and this feature can be used for the differentiation of the organism from other gram-negative coccobacteria. nitrofurantoin paper disks (300 mug) failed to affect the growth of 150 strains of b. bronchiseptica isolated from different animal hosts, but they produced marked inhibition zones in the cultures of the followingspecies: pasteurella multocida, pasteurella pneumotropica, pasteurella haem ...1975809944
avian cholera in eider ducks in maine.outbreaks of avian cholera (pasteurella multocida) occur frequently in common eiders (somateria mollissima dresseri) in maine during early summer. studies over a seven year period show that over 90% of the loss occurred in incubating females and might be associated with their weakened condition because females do not feed during the incubation period. high nesting densities also may contribute to the losses. the exact source of p. multocida is unknown although carrier birds were found.1978650794
effect of bursectomy and thymectomy on pasteurella multocida infection in chickens.the effects of various treatments on the immune response of chickens to vaccine prepared from pasteurella multocida strain p1059 were investigated. the treatments, given on or before the day of hatching, consisted of surgical bursectomy (sb), hormonal bursectomy (hb), surgical thymectomy (st) and x-irradiation (x). in chickens subjected to sb, sbx or hb before vaccination, the production of agglutinin and immunoglobulin was impaired, but the production of resistance against challenge was not. in ...1978682178
the january 1977 avian cholera epornitic in northwest california.a total of 844 birds were observed dead at three sites in humboldt county and an estimated 6750 birds died at three sites in del norte county, california. coots were the primary species affected. the isolation of pasteurella multocida from a snowy egret (egretta thula) is the first reported case of avian cholera in this bird. there was evidence for a distinct sequence in the bird species dying at one site; american coots (fulica americana) appeared to be the first species to die.1978691123
immunogenic activity of a ribosomal fraction obtained from pasteurella multocida.the cells of p. multocida strain p-1059 were destroyed with the french pressure cell; the ribosomal fraction proven to be homogeneous by analytical ultracentrifugation was obtained from the product by centrifugal fractionation, zonal electrophoresis, and sephadex g-200 gel filtration. the ribosomal fraction exhibited intense protective antigenicity in mice and chickens, but the lipopolysaccharide (endotoxin) and the other bacterial cell fraction obtained in this experiment did not. sodium deoxyc ...1977832895
[effect of aspirin and indomethacin on changes caused by pateurella multocida toxins in calves].acetylsalicyclic acid acid (50 mg/kg die) and indomethacin (1.5 mg/kg die) were administered to calves three days prior to intravenous application of endotoxin. such treatment resulted in delayed occurence of clinical symptoms and higher survival rates, as compared to untreated controls. parameters relating to coagulation physiology, changed by endotoxin, were not controllable with statistical security by administration of acetylsalicyclic acid indomethacin.1978666518
pasteurella multocida as a cause of vomiting and diarrhea in a 4-year-old boy. 1978670843
characterization of an immunogenic fraction of pasteurella multocida culture filtrates.an immunogenic fraction (if) of pasteurella multocida strain p-1059 was separated from culture filtrate by sephadex gel filtration. additional fractionation of if with aqueous ether resulted in the glycoprotein-like preparation (glp) while extraction with aqueous phenol provided the lipopolysaccharide-like preparation (lpp). the unextracted if contained carbohydrate, protein, and lipid; the glp contained carbohydrate and protein; and the lpp contained carbohydrate and lipid. the glp was maximall ...1977837254
pasteurella multocida from canine and feline teeth, with a case report of glossitis calcinosa in a dog caused by p. multocida.a case of glossitis calcinosa in a dog caused by pasteurella multocida is reported. swelling of the tongue and reduced appetite were the predominant clinical symptoms. due to latent infections with p. multocida in many species there is a risk of bitewounds being infected with this microorganism. in order to find the carrier-rate of p. multocida samples in canines, teeth and gingiva of 121 dogs and 30 cats were examined bacteriologically, revealing a carrier rates of 55% and 80% respectively. the ...1978693275
interaction between a hog cholera vaccine strain and pasteurella multocida in the production of porcine pneumonia. 1978659677
[pasteurella multocida infections in man after dog bites and cat scratches]. 1977847672
synthesis and antibacterial activity of isomeric 6- and 7-acetyl-3-methyl-2- quinoxalinecarbozamide 1,4-dioxides.the synthesis, separation, and structure determination of 6- and 7-acetyl--3-methyl-2-quinoxalinecarboxamide 1,4-dioxides are reported together with a comparison of their antibacterial activity. the structural assignment of these 6- and7-acetyl isomers was based on nmr analysis of related mono-n-oxide derivatives, which were obtained by treatment of the quinoxaline 1,4-dioxides with acetic anhydride--acetic acid or trimethyl phosphite. the compounds were screened for in vitro and in vivo activit ...1978660596
[use of attenuated mutants of pasteurella multocida strain, pathogenic to calves, in experimental mouse model studies. 4. immunogenicity of selected revertants of temperature-sensitive, streptomycin-dependent mutants as potential vaccine strains].temperature-resistant or streptomycin-independent revertants were isolated from temperature-sensitive or streptomycin-dependent mutants of a pasteurella multocida strain with pathogenicity to calf. the revertants were tested for virulence in mice and for their immunogenicity against wild-strain infection, using 100 times and more of the lethal dose. the following conclusions may be derived from the results thus obtained: 1. most of the fully attenuated streptomycin-independent revertants failed ...1978749742
studies on pasteurella multocida. vi. nature of systemic immunity and analysis of the correlation between levels of immunity induced by various fowl cholera vaccines and protection against challenge.the nature of the systemic immunity induced by various vaccines against fowl cholera disease in turkeys was investigated. used as vaccines were three avirulent strains (cu, m2283, and p1580) of pasteurella multocida administered in the drinking water and a bacterin administered parenterally. a passive hemagglutination test was developed to measure levels of systemic humoral immunity. systemic cell-mediated immune response was assayed by an in vitro immunostimulation microculture system utilizing ...1978749893
characterization of pasteurella multocida isolates from the nares of healthy rabbits with pneumonia.pasteurella multocida was isolated from 42 of the 135 (31%) deep nasal swabs from clinically healthy conventional rabbits supplied by two vendors. the prevalences were significantly different among sex, age, and sources. the females and adults had higher prevalences when compared to males and juveniles, respectively. one vendor's rabbits had a prevalence of 41% while the other had 20%. biochemically, only 24% of the 42 isolates decarboxylated l-ornithine, and 55% produced indol. all isolates wer ...1978750729
subcutaneous vaccination of chickens with a live, avirulent pasteurella multocida, vaccine.the immunogenic responses to various routes of vaccination of broiler-type chickens to the clemson university strain of pasteurella multocida were evaluated. broilers were vaccinated at 9 or 10 weeks of age using the oral (drinking water), palatine cleft, ocular, or subcutaneous injection routes. all birds were challenged at 11 or 12 weeks of age with virulent x-73 strain of p. multocida by the palatine cleft method. the degree of efficacy of the various vaccination routes differed among three e ...1978751031
determination of corticosterone concentration in plasma of turkeys using raioimmunoassay.a method of determining corticosterone concentration in turkey plasma was developed using radioimmunoassay. compared to fluorometric analysis and competitive protein-binding radioassay, this method had the following advantages: 1) results were consistent, 2) the method was simple and rapid to perform, 3) only 20 lambda of plasma was required, 4) all procedures were performed using the same tube except for counting, and 5) unknown and standard samples were treated identically. the coefficient of ...1978751044
clostridium pseudotetanicum bacteremia in a patient with pasteurella multocida conjunctivitis.clostridium pseudotetanicum only once previously has been identified as causing disease. pasteurella multocida has been identified only three times as the cause of purulent conjunctivitis. a very debilitated patient had c. pseudotetanicum bacteremia and p. multocida conjunctivitis from which she recovered only to die of a nosocomial staphylococcus epidermidis septicemia, originating in a site for the administration of intravenous fluids.1978730826
[pasteurella multocida infections in man unrelated to animal bites]. 1978740987
pasteurella multocida peritonitis in hepatic cirrhosis with ascites.two patients with spontaneous pasteurella multocida peritonitis in association with cirrhosis and ascites are described. both patients had close contact with domestic animals, but neither had been bitten. both patients died, but only one as a result of his infection. we are aware of only one previous report of cirrhosis with spontaneous peritonitis caused by this organism. p. multocida should be considered as a possible cause of peritonitis in cirrhotic patients with a history of close contact w ...1976765189
effect of active and passive immunizations with lipid a and salmonella minnesota re 595 on gram-negative infections in mice.the capacity of lipid a, a structure common to the lipopolysaccharide cores of all gram-negative bacteria, to serve as an active immunizing agent in mice and to protect these animals against gram-negative infections was investigated. active immunization experiments were also performed with the re mutant of salmonella minnesota 595 which carries a lipopolysaccharide composed of lipid a and three residues of ketodeoxyoctonic acid. single injections of lipid a complexed to acid-hydrolyzed bacteria ...1976789248
serological tests as indicators of immunity against pasteurella multocida infection in sheep.five serological tests, i.e. single tube agglutination, doubling dilution tube agglutination, agar agglutination, passive hemagglutination and passive mouse protection tests were evaluated for their efficacy in predicting the fate of vaccinated and unvaccinated sheep on challenge with an ovine strain of pasteurella multocida. the passive hemagglutination test predicted the fate of unvaccinated sheep while the agar agglutination test indicated the immune status of vaccinated sheep.1978743601
fever and reduced iron: their interaction as a host defense response to bacterial infection.when rabbits are infected with pasteurella multocida, the concentration of iron in their plasma decreases and their rectal temperature rises. to determine whether the rise in body temperature (fever) and the fall in plasma iron may be a coordinated host defense response, pasteurella multocida were grown in vitro at various temperatures and iron concentrations. at afebrile temperatures the bacteria grew equally well at low or high concentrations of iron. however, when the temperature of the bath ...1979760197
pasteurella multocida serotyping results (1971-1973).pasteurella multocida serotyping results were compiled and reported for 1971-1973. a total of 762 isolations from 20 different animal species from 23 states were serotyped. serotype 3 was most common, accounting for 53% of the isolations.1975808205
the serological and immunological relationship of type strains a and d of pasteurella multocida to field isolates from sheep.investigations with antisera prepared in rabbits and sheep and active immunity experiments in mice showed that strains of pasteurella multocida which, according to the haemagglutination test, are serologically related, do not necessarily give rise to cross immunity. conversely, it was found that serologically unrelated strains may exhibit an appreciable degree of cross protection. the unreliability of the haemagglutination test as an indicator of immunological identity of strains was further con ...1978754121
fowl cholera; cross-protective turkey antisera and igg antibodies induced with pasteurella multocida-infected tissue bacterins.turkey antisera induced with formolized pasteurella multocida-infected tissues (t antisera) passively cross-immunized 48 of 55 chickens against a challenge dose of p. multocida organisms, from which 0 of 15 controls survived. however, turkey antisera induced with formalin-killed, agar-cultured p. multocida cells (a antisera) passively cross-immunized only 4 of 30 chickens. cross-immunity refers to protection against a different immunologic type of p. multocida. quantitative precipitin reactions ...1975804994
mechanisms of acquired resistance to pasteurella multocida infection: a review.pasteurella multocida is an animal parasite of considerable economic and veterinary importance. the organism produces both capsular polysaccharide and somatic (lipopolysaccharide) antigens used to serotype the organisms. correlations exist between antigenic structure, host susceptibility and strain virulence. the host response seems to be predominantly polymorphonuclear in nature, with little evidence of a mononuclear component in the host response to infection. in the absence of specific opsoni ...1977832473
fowl cholera: immunologic and werologic response in turdeys to live pasteruella multocida vaccine administered in the drinking water.live fowl cholera vaccine administered in drinking water induced immunity in young turkeys against a challenge of a different immunogenic type of pasteurella multocida; this is referred to as cross-immunity. serum from the vaccinated birds induced passive cross-immunity in chicks and turkeys; this demonstrated that the cross-immunity induced with the drinking water vaccine was associated with the humoral system. results of serologic tests with agar grown p. multocida indicate that agglutinins ...1975806065
immunogenic and toxic properties of a purified lipopolysaccharide-protein complex from pasteurella multocida.an immunogenic fraction from pasteurella multocida was found to consist chiefly of a high-molecular-weight protein-polysaccharide complex containing 25 to 27% protein and 10.7% carbohydrate. the starting material was obtained by differential centrifugation at 105,000 x g of saline extract of p. multocida cells and further purified by gel filtration on sepharose 2b. three peaks were usually obtained after gel filtraion.pharose 2b. three peaks were usually obtained after gel filtration. the compon ...1976825472
pasteurella multocida pleural empyema. 1978722450
acquired resistance in turkey poults to pasteurella multocida (p-1059 strain) during aflatoxin consumption.the potential for impairment by aflatoxin of the development of acquired immunity to fowl cholera in 8 week old turkey poults from a commercial flock was investigated by challenge of vaccinated poults at 10, 12, and 16 weeks of age. sixty poults were allotted to 4 groups: a) aflatoxin fed, nonvaccinated; b) aflatoxin fed, vaccinated; c) control fed, nonvaccinated; and d) control fed, vaccinated. aflatoxin b-1 (.5 ppm) was added to the control ration of groups a and b from 49 to 70 days of age. t ...1978724596
treatment with oxytetracycline hydrochloride in the prevention of atrophic rhinitis in baby pigs.atrophic rhinitis (ar) caused serious losses in a breeding herd including approximately 120 sows. the extent to which piglets were affected by ar was assessed by determining the degree of shortening of the upper jaw. animals showing a crooked nose or grade two or more of shortening of the upper jaw were considered to be clinically positive. grades three and four of the upper jaw were observed in those animals which were severely affected by atrophic rhinitis. treatment of all piglets up to about ...1977835133
use of bacteriophages as an adjunct in the identification of pasteurella multocida.bacteriophages were used as an adjunct to biochemical reactions in the identification of pasteurella multocida. with the use of bacteriophages, rapid definitive identification of 52.4% of 61 p multocida isolates was made.1977835860
fowl cholera: induction of cross-protection in turkeys with bacterins prepared from host-passaged pasteurella multocida.modified fowl cholera bacterins prepared by inoculating agar medium with infected liver tissue from birds which died of acute fowl cholera induced 70% cross-protection in turkeys, i.e., protection against a different immunologic type of pasteurella multocida. standard bacterins prepared from cultures which had been lyophilized and stored showed variable cross-protection (0--40%). repeated subculturing of the standard inoculum on agar reduced cross-protection. the protection with either the modif ...1977843303
[measures to be adopted in the prevention and treatment of atrophic rhinitis in piglets under field conditions (author's transl)].the following measures designed for the prevention of atrophic rhinitis (ar) were compared. (1) adopting the all in - all out system in separate farrowing quarters. the variation in age between piglets in a single farrowing house was confined to one to two weeks. (2) treating the piglets with a combined preparation of penicillin, chloramphenicol, oxytetracycline hydrochloride or sulphonamides on the third, sixth and twelfth days of life. (3) administering immune sera to piglets. (4) vaccinating ...1977847733
[characterization of the lipopolysaccharides of various pasteurella multocida strains].the occurrence of monosacharides, glucosamine, galactosamine, l-glycero-d-mannoheptose, d-glycero-d-mannoheptose, glucose, and galactose in the lipopolysaccharides of pasteurella multocida is likely to support subdivision into four chemical types which, however, are not equivalent with serotypes.1977849103
[problems in the use of radioactively marked bacteria in animal experiments. 1. labeling of pasteurella multocida, pasteurella haemolytica and salmonella dublin with eh, 14c, 32p, 59fe, 99mtc, 125j1].several methods are suggested by which to use the radionuclides 3h, 14c, 32p, 59fe, 99mtc, and 125j for labelling or doublelabelling of pasteurella multocida, pasteurella haemolytica, and salmonella dublin, with particular reference being made to labelling ofr animal experiments. suitable radioactive substrates for internal labelling in chemically defined or partially defined nutritive media include 3h-thymin, 3h-thymidine, 14c-glucose, 14c-mannose, 14c-aspartic acid, as well as 3h-uracil, 3h-ur ...1977849104
[antagonistic action of pseudomonas aeruginosa in relation to pasteurella multocida strains].studied was the antagonistic action of 4 strains of pseudomonas aeruginosa toward 48 strains of pasteurella multocida. use was made of the method of the delayed antagonism after fredericq. ps. aeruginosa organisms were found to manifest a strongly expressed antagonistic activity as regards p. multocida. all pasteurella strains proved highly sensitive, and showed a zone of inhibited growth sizing from 20 to 70 mm. the antibiotic substance produced by pseudomonas aeruginosa organisms was yielded b ...1976829004
[atrophic rhinitis in swine].four 60-day-old pigs were experimentally infected with bordetella bronchiseptica at a state in which the animals were clinicylly normal. a single pig only, killed on the 180th day, presented a slight deflection of septum nasi. morphologically, there were severe dystrophic and necrotic changes in the mucosa of the conchae, the nasal cartilages as well as in the bones. the pathogen was reisolated from two of the pigs. clinical and morphological investigations were carried out also with spontaneous ...1978706148
partial characterization of r-plasmids from pasteurella multocida isolated from turkeys.pasteurella multocida, isolated from turkeys during an outbreak of septicemic disease ("fowl cholera"), was found to be resistant to tetracycline, streptomycin, and sulfonamides. agarose gel electrophoretic analysis of dna from these isolates indicated the presence of extrachromosomal elements. plasmid dna was isolated by cesium chloride-ethidium bromide density centrifugation. escherichia coli was transformed to antimicrobic resistance with this dna. two plasmids were isolated. one of these pla ...1978708012
immune response of medicated turkeys vaccinated with live pasteurella multocida.in 3 experiments, turkeys were vaccinated with the clemson university strain of pasteurella multocids (cu) via the drinking water for 1 or 3 days while they were fed 3 different rations. ration 0x consisted of non-medicated turkey starter, ration 1x had 0.00625% sulfadimethoxine and 0.00375% ormetoprim added, and ration 2x had 0.0125% sulfadimethoxine and 0.0075% ormetoprim. immune response was determined by challenge exposure with pathogenic p multocida, either serotype 3 or serotype 4, adminis ...1977851281
evaluation of two avirulent vaccines for preventing experimental fowl cholera in turkeys, and use of one vaccine in the field.the clemson university (cu) strain of live cholera vaccine administered in water (lcvw) was effective in immunizing turkeys against the pulmonary, arthritic, and cranial forms of fowl cholera. the missouri strain of lcvw immunized turkeys against the pulmonary and septicemic forms of fowl cholera. pasteurella multocida was isolated from the orifice of the auditory tube of 5% of the turkeys vaccinated with the cu strain 2 weeks postvaccination, but not 4 weeks after challenge. mortality was not i ...1977869825
the inhibitory effect of corynebacterium parvum and pasteurella multocida pretreatment on staphylococcal synovitis in turkeys.corynebacterium parvum and pasteurella multocida were shown to be immunostimulants in turkeys, increasing the ability of whole blood to kill staphylococcus aureus and prolonging the incubation time of experimental staphylococcal synovitis.1977869828
suppurative otitis media in the rabbit: prevalence, pathology, and microbiology.the middle ears of 2001 young and 583 adult rabbits being slaughtered for human consumption were examined. otitis media was found in 87 (4%) of the young rabbits, and in 188 (32%) of the adult rabbits. the condition was bilateral in 61% of the affected young rabbits and 70% of the affected adults. pasteurella multocida was isolated from 60 (98%) of 61 affected young rabbits. the gross and microscopic lesions and secondary complications were similar to those described in children. rupture of the ...1977875360
[biochemical, morphological and immunological characteristics of the cytoplasmic membranes isolated from pasteurella multocida]. 1977878290
[pasteurella multocida infections following dog and cat bites]. 1977892639
acute pasteurella multocida pneumonia.acute pneumonia caused by pasteurella multocida appeared in two elderly patients. one patient had chronic obstructive lung disease and the other developed aspiration pneumonia after an episode of cardiac arrest. pasteurella multocida was not isolated from the initial sputum cultures. the delay in recognizing the pathogen resulted in extension of the pneumonia and abscess formation in the patient with obstructive lung disease. pasteurella multocida was isolated from a percutaneous transtracheal a ...1977861154
pasteurella multocida pneumonia and bacteremia.a 76-year-old man with chronic obstructive pulmonary disease who developed p multocida pneumonia and bacteremia has been described. the infection was treated with antibiotics, and the patient recovered. pasteurella multocida is known to infect many species of animals. the instances of human infection due to this organism are frequently associated with exposure to animals. pulmonary infection occurs principally in patients with underlying chronic bronchopulmonary disease.1977897740
an epornitic of avian cholera in waterfowl and common crows in phelps county, nebraska, in the spring, 1975.in the spring of 1975, many species of waterfowl and common crows (corvus brachyrhynchos) were found dead in phelps county, nebraska. about 25,000 water fowl and at least 3,000 crows died in the epornitic. few waterfowl were seen dying, but the crows experienced a chronic illness during which they became debilitated and were lethargic and dyspneic. gross and microscopic lesions in the waterfowl were typical for acute avian cholera. the crows had dark, firm areas within the lungs, loosely adhered ...1977864853
phycomycosis associated with encephalitis caused by haemophilus somnus in a heifer.numerous fungal hyphae resembling those of a phycomycete were found in thrombi, vessel walls, and areas of inflammatory cell infiltration within a large focus of necrosis in the brainstem of a 2-year-old heifer. haemophilus somnus and pasteurella multocida were isolated from the same lesion. antemortem hyperglycemia was also demonstrated.1977903285
comparison of low-level rofenaid, low-level chlortetracycline, and vaccination with commercial bacterin for preventing pulmonary form of fowl cholera in turkeys.the pulmonary form of experimentally induced fowl cholera was controlled effectively either by rofenaid, a potentiated sulfadimethoxine, at 0.01% in feed, chlortetracycline at 0.0055% in feed, vaccination with a commercial fowl cholera bacterin and a combination of rofenaid and vaccination. the medicated or/and vaccinated turkeys had a significantly (p less than 0.05) better livability than the unmedicated or unvaccinated exposed turkeys. turkeys were exposed by contact with carriers and adminis ...1977869823
[influence of pasteurella multocida and pasteurella-multocida endotoxin on the blood-coagulation-analytic parameter after experimental administration in calves].experimental administration to calves of pasteurella multocida or the application of an endotoxin preparation of the strain produced continuous decline of thrombocytes, disorders in thrombocytic functions, and the development of hypofibrinogenaemia. the changes recorded as well as the clinical symptoms and pathologico-anatomic findings are interpreted as endotoxin shock.1977901129
[binding relationships of fatty acids in lipid a of lipopolysaccharides from pasteurella multocida].each glucosamine disaccharide of lipid a from pasteurella multocida contains 2 mols myristic acid and 4 mols hydroxymyristic acid. 3-hydroxymyristic acid was identified as fatty acid with amide linkage. every 2 mols of glucosamine have linked to them 1 mol myristic acid, 3-hydroxymyristic acid, and 3-myristoxymyristic acid. the results so far obtained reflected the structure of lipid a of enterobacteriaceae.1977901126
endocarditis caused by pasteurella multocida.a 51-year-old previously healthy man developed endocarditis with low grade fever, aortic insufficiently and multiple arterial emboli. an atypical strain of pasteurella multocida was isolated from each of 3 consecutive blood cultures. protracted treatment with high doses of penicillin g was necessary to eradicate the infection. following resection of the damaged aortic valves and implantation of a valve prosthesis, the patient recovered. p. multocida should be regarded as one of the possible caus ...1977905786
a bacterin against fowl cholera in turkeys: protective quality of various preparations originated from broth cultures.bacterins prepared from broth cultures of pasteurella multocida were studied for their immunogenicity against fowl cholera in turkeys. the various preparations differed in culture medium, method of inactivation, and adjuvants added. eight-to-twelve-week-old turkeys were inoculated subcutaneously with each preparation. after challenge with a live culture of the homologous strain, protection was significantly better from a broth bacterin grown in brain-heart infusion broth, concentrated tenfold, i ...1977907580
toxic effects of cadmium microparticles on the respiratory system. an experimental study on rats and mice.an experimental study on rats and mice. scand. j. work environ. & health 3 (1977) 116--121. experiments on male, specific pathogen-free rats (193) and mice (66) are reported. the test and control animals received a single 15-min exposure to cadmium (cadmium oxide) and aluminum (alumina) microparticles, respectively. the air cadmium content was 10 mg/m3, and 4 microgram of this metal was retained by the lungs of the rats. the animals were observed for 24 days. the following significant difference ...1977910121
pasteurella multocida infection of urinary tract in patient with ileal loop.pasteurella multocida infection in the ileal loop and in the pelvis of a hydronephrotic kidney of a patient whose other kidney had been removed at age six months was documented by the repeated isolation of this patthogen. two episodes occurred, the first terminated after a dose of gentamicin and the other without chemotherapy. since the patient prior to infection was in severe renal failure necessitating hemodialysis, the effect of this infection on renal function could not be ascertained. the p ...1977841805
multiple drug resistance in pasteurella multocida and pasteurella haemolytica from cattle and swine.the results of antimicrobial susceptibility testing on 262 strains of pasteurella multocida and 141 strains of pasteurella haemolytica isolated from cattle and swine from 1971 to 1974 were analyzed for patterns of resistance to streptomycin, penicillin, tetracycline, and chloramphenicol, using a modified kirby-bauer procedure. resistance was recorded for 80.5% of the isolants of p multocida and 92.2% of those of p haemolytica. resistance to streptomycin was most frequent, followed by resistance ...19761048955
pasteurella multocida meningitis in an infant with recovery. 1977912280
septic polyarthritis associated with bacterial endocarditis in two dogs.two dogs were examined because of chronic shifting lameness. in each case, lameness was attributed to septic polyarthritis, as documented by synovial fluid analysis and culture. in 1 dog, antemortem diagnosis of bacterial endocarditis was verified by clinical and culture data. treatment of both dogs was unsuccessful, and necropsy of each dog revealed bacterial endocarditis with coexistent septic polyarthritis. bacteriologic blood cultures yielded an anaerobic streptococcus sp (dog 1) and pasteur ...1977914687
treatment of captive giant canada geese affected by avian cholera.in the spring of 1975, an epornitic of avian cholera in nebraska affected wild waterfowl, common crows (corvus brachyrhynchos), and a captive flock of guant canada geese (branta canadensis maxima). measures taken to control the disease in the captive geese included flushing the water of their pen with fresh well water, parenteral (50mg oxytetracycline intramuscularly) and feed (tetracycline 500 g/ton) antibiotic treatment, and removing dead waterfowl and crows from the pen, and keeping wild wate ...1977916145
demonstration of bacteriocin activity in bovine and bison strains of pasteurella multocida.of 33 strains of pasteurella multocida examined, 14 showed bacteriocin activity and 17 were susceptible to bacteriocin. the activity was increased by about twofold if the cultures were induced with ultraviolet radiation; however, no increase in bacteriocin activity was observed if the potential producer strains were induced with mitomycin c. the bacteriocin activity of potential producer strains was increased if cacl2 was incorporated in the medium. the patterns of bacteriocin susceptibility ind ...1977911086
pasteurella multocida infection after a dog bite. 1976945443
[a case of fowl cholera (pasteurella multocida) in six-week-old broilers (author's transl)].an outbreak of fowl cholera in a broiler-house with 6,000 six-week-old broilers is reported. the birds were affected with respiratory disease when they were four weeks old. eight days after recovery, at an age of six weeks, 50 per cent of the birds were severly ill. the birds were reluctant to move and unable to drink. four hundred birds died in one day. post-mortem examination revealed marked swelling of the kidney and arthritis of all the hocks and knee joints in all fifteen birds studied. pur ...1976951698
[enzootic dermonecrosis in chickens].an enzootic of necrotic dermatosis in hen layers was described. the changes consisted in that they had constant localization and demarkated sites on the skin between the back and the neck. the disease was observed on a farm for 5000 layers in the course of two consecutive years. all birds contracted the disease and in the first year they recovered the 10 months; in second year they recovered for three months. each bird showed symptoms for 3 weeks. the skin lesions resulted in cicatrization. the ...1976951928
bronchiectasis in yearling feedlot cattle.thoughout all of 1974, we surveyed, for illnesses and deaths, about 407,000 yearling feedlot cattle. from the 3,943 dead cattle, 1,988 necropsies were made; of the cattle necropsied, 32 (1.6%) had bronchiectasis. in this disease, the permanently dilated small bronchi and bronchioles, located in ventral parts of the lungs, were filled with accumulations of exudate and microorganisms, including pasteurella hemolytica, pasteurella multocida, corynebacterium pyogenes, escherichia coli, salmonella an ...1976956033
[lysogeny in pasteurella multocida].studied was the possibility of lysis-producing factors (the phenomenon of lysogeny) with 59 strains of pastuerella multocida isolated in bulgaria, cuba, and czechoslovakia. it was found that eleven of them were lysogenic in terms that a total of 12 bacteriophage strains were isolated from them; one of them yielded 2 phages. established were three different indicator strains of pasteurella multocida-97, shd, and r-ii--by means of which 3 different groups of p. multocida phages were isolated. the ...1976960551
two cases of pasteurella multocida infections in jamaica. 1976960694
[end products of glucose fermentation of pasteurella multocida and p. haemolytica]. 1976960734
[post-traumatic meningitis due to pasteurella multocida].the clinical data of a 14-year old female patient with posttraumatic meningitis by pasteurella multocida are reported. the behaviour of the isolated strain is recorded in cultural and biochemical aspect as well as in animal experiment. the importance of the infection with pasteurella multocida is lined out and the possible origin of the disease in the reported case is discussed. finally some problems of special bacteriological diagnosis are explained and hints are given in this respect.1976960883
effect of furazolidone in feed on immune response of turkeys vaccinated with live pasteurella multocida in drinking water.in 2 trials, turkey poults were fed diets containing 0.011% furazolidone: in one trial until 2, 3, 4, 5, 6, or 7 days before vaccination with live pasteurella multocida (cu) in the drinking water; and in a second trial with the furazolidone added to the diet 4 days before the vaccination or 1, 3 or 5 days after. this 0.011% level of medication did not appear to reduce the immune response.1976962760
the effect of sulfaquinoxaline feed medication on the immunologic response to a pasteurella multocida vaccine administered to turkeys via drinking water.five groups of turkeys received c.u. strain pasteurella multocida vaccine in the drinking water for one day. one group received the 0.1% level of sulfaquinoxaline feed medication at the time of vaccination, while 4 other groups received the feed medication 1, 2, 3 and 4 days after vaccination, respectively. two weeks after vaccination all groups were exposed to a virulent p-1059 strain of p. multocida by the drinking water route. the results suggest that turkeys on the feed medication at the tim ...1976934983
physiologic characteristics of 1,268 cultures of pasteurella multocida.results of 29 physiologic tests are reported for 1,268 cultures of pasteurella multocida from various hosts over a 10-year period. of the cultures, 97 to 100% fermented galactose, glucose, mannitol, mannose, fructose, and sucrose, produced hydrogen sulfide and indole, and reduced nitrate; 6 to 91% fermented arabinose, glycerol, sorbitol, trehalose and xylose. fermentation of dextrin, dulcitol, inositol, inulin, lactose, maltose, raffinose, rhamnose, and salicin, growth on macconkey agar, change ...1976937797
experimental production of infectious bovine keratoconjunctivitis: comparison of serological and immunological responses using pili fractions of moraxella bovis.the effect of vaccinating cattle and mice on the development of keratoconjunctivitis was studied. cattle were vaccinated with whole cells, disrupted cells and pili fractions of three strains of moraxella bovis. mice were vaccinated with pili fractions of three strains. the resistance of all vaccinated animals was challenged with virulent cultures of m. bovis. in an attempt to correlate the response seen after vaccination and challenge with a pili fraction of m. bovis, vaccinated cattle and mice ...19761000379
sulfhydryl compounds in melanocytes of yellow (ay/a), nonagouti (a/a), and agouti (a/a) mice.cleffmann (1953, 1963a,b) has reported that yellow but not black melanocytes of agouti (a/a) rabbits contained reducing sulfhydryl compounds. we have attempted to repeat cleffmann's observations in mouse melanocytes of the lethal yellow (ay/a), nonagouti (a/a) and agouti (a/a) genotypes. our results contradict those of cleffmann and reveal that yellow and black melanocytes, regardless of genotype, possess equivalent amounts of histochemically detectable sulfhydryl compounds. these results do not ...19761001879
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