| [immunoprofile of lmif in immunologic deficiency syndromes. ii. mediator production by isolated subpopulations of human lymphocytes]. | | 1978 | 149303 |
| blood-brain barrier opening by isotonic saline infusion in normotensive and hypertensive animals. | the blood-brain barrier to intravascular evans blue-albumin was opened in monkeys and rabbits by infusing isotonic saline for 15 s into the common carotid artery, when the external carotid was clamped temporarily and the lingual was catheterized for measuring pressure. barrier opening correlated better with infusion pressure than with infusion rate, and occurred at carotid artery pressures above 170 mmhg. systemic hypertension induced by aramine increased barrier vulnerability by causing a highe ... | 1978 | 104549 |
| antigenic relationship between influenza c viruses. | the object of this study was to determine whether antigenic groupings exist among influenza c viruses. altogether seven influenza type c strains were examined by reciprocal haemagglutination-inhibition and serum neutralization tests with sera produced in ferrets. some biological properties were also compared and differences were found in their ability to agglutinate erythrocytes from various species, in their ability to adsorb onto rat and fowl erythrocytes, and in their rates of elution from th ... | 1978 | 104696 |
| isolation and characterization of an endogenous inhibitor of protein synthesis in escherichia coli k-12. | a low-molecular-weight factor was isolated from cell extracts of escherichia coli k-12. the concentration of the factor in cells was dependent upon nutritional conditions, the concentration being higher in faster growing cells. treatment of cells with colicin k caused an increase in concentration of the factor. the factor inhibited protein synthesis in e. coli. this inhibition was reversible, apparently because of metabolism of the factor. the inhibition of synthesis of beta-galactosidase lasted ... | 1979 | 104965 |
| membrane changes during growth of tetrahymena in the presence of ethanol. | after a brief lag period for acclimation, tetrahymena pyriformis, strain nt-1, is capable of growing in culture medium containing high levels of ethanol. when grown in a medium having 1.6% ethanol, the membrane phospholipid composition was significantly different from that of control cells. the principal changes included a reduction in hexadecenoic acids (16 : 1 and 16 : 2) from 23% to 5% and an increase in linoleic acid (18 : 2) from 14% to 25% similar but less pronounced changes were observed ... | 1979 | 105757 |
| morphologic and functional characteristics of human intestinal lymphoid cells isolated by a mechanical technique. | | 1979 | 153255 |
| chromosomal aberrations and congenital heart diseases. | the incidence of chromosomal aberration with chd is 10.5% in the autopsy cases. 2. the characteristic major cardiac malformations associated with chromosomal aberration are conal abnormality, abnormal septation and cardiac valve abnormalities. 3. the characteristic association of chromosomal aberration and chd is cavo in down syndrome, triple shunts and multivalvular disease in 18 trisomy, shunts in delition syndrome and coarctation of the aorta in turner syndrome. 4. minor cardiac anomalies ass ... | 1978 | 153412 |
| mutual antagonism of behavioral effects of trh and thiobarbiturate on an operant task in rhesus monkeys. | similar excitatory or depressant response rate dependent effects on monkeys responding on a variable interval reinforcement schedule were observed following intravenous administration of either thyrotropin releasing hormone (trh) or thiobarbiturate. however, these agents were mutally antagonistic when given together even though the response rate altering effects of each agent were in the same direction. these findings establish an additional behavioral effect of exogenously administered trh in p ... | 1979 | 108712 |
| focal loss of alkaline phosphatase and increase of proliferation in preneoplastic areas of the rat urothelium after administration of n-butyl-n-(4-hydroxybutyl)-nitrosamine and n-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide. | development of tumours of the urinary bladder was studied in 59 male and female sprague-dawley and wistar rats with combined enzyme-histochemical and autoradiographic methods after oral application of n-butyl-n-(4-hydroxybutyl)-nitrosamine (bbn) and n-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide (fanft). as the first carcinogenic lesion detectable by light-microscopy a focal, sharply defined irreversible loss of alkaline phosphatase activity was consistently demonstrated in the urothelium, which a ... | 1975 | 127442 |
| monoaminergic mechanisms in aversive brain stimulation. | in these experiments we have examined the role of brain monoamines in the fearlike aversive responses produced by the electrical stimulation of the dorsal midbrain tegmentum (dmt). chronic bipolar stimulating electrodes were bilaterally implanted into the dmt of 77 rats. electrical stimulation via 34 of these electrodes produced fearlike, escape seeking responses. these animals were then trained for stable stimulus escape using a decremental bar pressing paradigm. in this paradigm, each bar pre ... | 1975 | 128009 |
| letter: petechiae: due to adenovirus type 7 infection or to acetylsalicylic acid therapy? | | 1975 | 165451 |
| microflora of pneumonic lungs in a pig herd established by hysterectomy. | mycoplasmas and other micro-organisms are recorded from a pig herd originally derived by hysterectomy. complement fixation tests were positive for mycoplasma hyopneumoniae 20 months after the first hysterectomy. following a marked increase in pneumonic lesions found at slaughter, and after modifying the culture medium m hyopneumoniae was isolated. the principal micro-organism associated with this mycoplasma was pasteurella multocida. | 1976 | 130669 |
| effects of implanted doppler flowmeters on femoral vein autografts. | thirteen femoral vein autografts were placed into the corresponding ipsilateral femoral arteries of 8 mongrel dogs. cuff-type doppler (ultrasonic) flowmeters were placed around six of the grafts. none of the vessels thrombosed. blood flow velocities were measured in all vessels up until the time of sacrifice (mean 95 +/- 5 days after surgery) or accidental death (one dog, 49 days after surgery). the only case of graft failure was attributed to infection at the flowmeter site. with this single ex ... | 1976 | 130843 |
| immune mechanism in pasteurella multocida-infected mice. | various immunizing procedures were tested for their effect on the growth of pasteurella multocida in specific pathogen-free cd-1 mice. two injections with killed vaccine incorporated into freund complete adjuvant gave excellent protection against parenteral challenge, but less to control the growth of an aerogenic inoculum. protection with adjuvant-treated preparation was always superior to that seen with non-adjuvant-treated vaccines. a killed saline-suspended vaccine introduced aerogenically m ... | 1976 | 131783 |
| recovery of preimplantation blastocysts in the squirrel monkey by a laparoscopic technique. | a laparoscopic uterine flushing technique has been developed for the recovery of preimplantation embryos from the squirrel monkey. fourteen adult female squirrel monkeys were induced to ovulate with 4 or 5 days' treatment with follicle-stimulating hormone (1 mg) followed by human chorionic gonadotropin (hcg) (500 iu). natural mating with a fertile male or artificial insemination was performed near the time of ovulation. thirty-six hours and eleven days after hcg administration, the females were ... | 1977 | 140077 |
| the influence of sodium, potassium and lanthanum on amino acid release from spinal-medullary synaptosomes. | | 1975 | 166144 |
| laparoscopic examination of the reproductive tracts of gilts using a special crate. | a crate for restraining gilts for routine laparoscopic examination of the reproductive tract is described, together with the techniques employed in anaesthesia and laparoscopy. the procedure is efficient, allowing two operators to examine 4-5 gilts per hour. | 1978 | 148883 |
| improved chemical synthesis and enzymatic assay of delta-1-pyrroline-5-carboxylic acid. | | 1975 | 166569 |
| [on the connections between the rami communicantes of the sympathicus and the rami posteriores of the loin nerves (author's transl)]. | the existence of anastomoses between the rami communicantes of the truncus sympathicus and the rami posteriores of the loin nerve in man has been confirmed macroscopically and microscopically in 50% of the cases. this is followed by a discussion of the causality of pains in the loin region. | 1978 | 150806 |
| antibody levels to parainfluenza, rubella, measles, and influenza a virus in children with polymyositis. | the cf and hi antibody titers to rubella and measles viruses, the cf titers to influenxa a, and the hi titers to parainfluenza 1, 2, and 3 were carried out on the sera of 20 patients with childhood polymyositis and their matched controls. the titers for measles, parainfluenxa 1, and influenza a were slightly higher for patients than for controls. the control group had antibody titers to rubella and parainfluenza 2 and 3 higher than or similar to those of patients. strong patterns or significant ... | 1975 | 168906 |
| [raised prostaglandin e-2 level in focal inflammatory lesions of the human skin with particular reference to rosacea]. | | 1978 | 151301 |
| ultrastructure of human bronchiolo-alveolar cell carcinoma. | ultrastructural features were correlated with a series of special staining reactions in eight cases of bronchiolo-alveolar carcinoma. ultrastructural, all tumors were similarly composed of large cells with abundant cytoplasm and small nuclei in close contact with each other. straight membranes or complex interdigitations occurred within adjacent tumor cells, attached to each other by scattered desmosomes. microvilli or cilia abutted from free surfaces of the cells, and were noted in different st ... | 1975 | 169987 |
| influence of some divalent cations on heart sarcolemmal bound enzymes and calcium binding. | | 1978 | 153143 |
| effects of five to seven days of sleep deprivation produced by electrical stimulation of the midbrain reticular formation. | | 1975 | 172366 |
| the fourth volhard lecture: cardiovascular structural adaptation; its role in the initiation and maintenance of primary hypertension. | | 1978 | 153216 |
| transducing activity of bacteriophage spp1. | | 1979 | 106856 |
| cytomegalovirus pulmonary disease. | | 1975 | 172837 |
| medical and surgical approach to laryngeal air sacculitis in a baboon caused by pasteurella multocida. | air sacculitis was diagnosed in a chronically chaired baboon, papio anubis. pasteurella multocida was repeatedly isolated from the air sac for a period of 1 year. the condition was characterized by the continuous accumulation of either mucoserous or purulent fluid. biopsies of the air sac taken during the course of the disease initially revealed goblet cell hyperplasia. later a subepithalial mononuclear or polymorphonuclear infiltrate and necrosis was the predominate finding. medical therapy was ... | 1978 | 108467 |
| double antibody specificity of lymphoid cells isolated from normal human intestinal mucosa. | lymphoid cells were isolated from normal human mucosal specimens. a certain fraction of these cells exhibited double antibody specificities at the levels of both light kappa and lambda chains and heavy mu and gamma chains. the variable frequency with which these cells were detected appears to be a characteristic of this population. they represent a very low proportion of the total number of cells isolated. | 1979 | 114243 |
| pharmacological modification of experimental tardive dyskinesia. | cebus apella monkeys subjected to chronic haloperidol administration develop neurologic disturbances very similar to neuroleptic-induced acute dystonia human beings. after varying lengths of time, certain monkeys develop a prolonged dyskinetic syndrome resembling tardive dyskinesia (td), as seen clinically. two monkeys with signs of td were given single intramuscular injections of various compounds with known effects on the catecholaminergic, cholinergic, serotoninergic and gaba-ergic neurotrans ... | 1979 | 115227 |
| serotyping of pasteurella multocida isolants from poultry. | a total of 607 pasteurella multocida strains were isolated in israel from turkeys, geese, and chickens. serotyping was carried out by the gel-diffusion precipitin test. the antigens were heat-stable saline extracts of the organisms, and the diagnostic sera were produced in chickens using formalinized bacterins. among 31 serotypes containing one to five antigenic factors, serotypes 1 and 3 accounted for 58.1%, 80.8%, and 88.9% isolants from turkeys, geese, and chickens, respectively. on the basis ... | 1979 | 118742 |
| [changes in carbohydrate metabolism in hens experimentally infected with pasteurella multocida kokoshki]. | studied were the concentration of blood sugar, the activity of glucose-6-phosphatase and glucose-6-phosphatedehydrogenase, and the level of glycogen in the liver of p. multocida infected chickens. an abrupt decrease of the liver glycogen was found as well as a negligible rise of the blood sugar. the activity of glucose-6-phosphatase remained unchanged, and that of glucose-6-dehydrogenase was twice as high. it is concluded that the intense exhaustion of liver glycogen is in connection with the ac ... | 1975 | 174282 |
| pasteurella multocida septicaemia associated with chronic liver disease. | | 1975 | 174776 |
| human cancer viruses. | | 1976 | 175647 |
| methionine transport in pseudomonas aeruginosa. | a high-affinity (km = 2.7 x 10(-7) m) energy-requiring methionine-transport system has been characterized in rm 46 and rm 48, two different pao methionine auxotrophs of pseudomonas aeruginosa. after 8 s of transport 40--60% of the methionine label in the alcohol extract appears in s-adenosyl-l-methionine (sam) with the remaining activity in free methionine. methionine transport required a high degree of structural specificity for transport. stimulation of transport occurred by addition of glucos ... | 1979 | 120222 |
| studies of immunogenicity of westphal lipopolysaccharides from pasteurella multocida in mice. | | 1979 | 120378 |
| [decarboxylase activity study of pasteurella multocida]. | ornithine-, lysine- and arginine-decarboxylase activity of 218 p. multocida strains, isolated from birds of varying disease symptoms in bulgaria and cssr, and from pigs, rabbits and birds in cuba, ussr and cssr, was studied after the method of moller. positive ornithine decarboxylase activity was established in 211 strains, low -- in 2, and negative -- in 5 strains. low arginine decarboxylase activity was observed in 12 pasteurella strains, while in 14 -- low lysine decarboxylase activity. the p ... | 1979 | 120631 |
| fatal immune complex glomerulonephritis without deposits. | repeated intravenous injections of egg albumin in rabbits produced small antigen-excess complexes and severe glomerulonephritis. immunoglobulins and complement in the glomeruli were not clearly demonstrated by immunofluorescence; deposits were found to be sparse by electron microscopy. this study demonstrates that soluble immune complexes are responsible for the glomerular reaction. the apparent absence of deposits is thus not sufficient to exclude an immune complex pathogenesis. | 1975 | 123971 |
| morphogenesis of the membrane-bound electron-transport system in sporulating bacillus megaterium km. | the properties of electron transport systems present in soluble and particulate fractions of spores of bacillus megaterium km?have been compared with those of similar fractions prepared from exponential-phase vegetative cells of this organism. the timing and localization of modifications of the electron transport system occurring during sporulation have been investigated by using a system for separating forespores from mother cells at all stages during development [8]. spore membranes contained ... | 1975 | 126154 |
| in vitro human reactivity to staphylococcal phage lysate. | the cell-mediated reactivity of normal individuals to staphylococcal phage lysate (spl) were tested in vitro in the lymphocyte stimulation (ls) and leukocyte migration inhibition (lmi) assays. there were 95% positive responses in ls (stimulation ratio larger than or equal to 3 with p less than 0.01) and 67% positive responses in lmi (migration index less than or equal to 0.80). enriched subpopulations of t and b lymphocytes were prepared with rosette formation and density gradient centrifugation ... | 1975 | 126257 |
| elementary particles in isolated rat liver and spleen nuclear membranes. | elementary spherical particles similar to those described in the mitochondria are found in isolated rat liver and spleen nuclear membranes. the particles are characterized by electron microscopy of sections and preparations negatively stained with phosphotungstic acid or with the atpase histochemical reaction product. the particles exhibit adenosine triphosphatase activity and have a mushroom-like shape with a sphere about 85-90 angstrom in diameter attached to inner face of the inner nuclear me ... | 1975 | 126876 |
| interrelationships between the central nervous system and patterns of adrenocorticotropic secretion following acute exposure to severe environmental conditions. | | 1976 | 187557 |
| serum modulation of in vitro cellular immune reactivity to epstein-barr virus-associated antigen. | the reactivity of peripheral blood leukocytes to epstein-barr virus-associated antigen was assessed employing two in vitro tests, leukocyte adherence inhibition (lai) and leukocyte migration inhibition (lmi). in both tests, autologous serum from some normal subjects was shown to confer strong reactivity on weak or non-responder cells. reactivity to purified protein derivative of tuberculin (ppd) assessed in parallel was shown to be unaffected by autologous serum. employing the lai system, variat ... | 1976 | 187919 |
| investigation of factors of probable significance in the pathogenesis of pneumonic pasteurellosis in cattle. | six groups of ten beef calves six to eight months of age were shipped from western canada and observed untreated for one week after arrival. the following parameters were measured daily: body temperature, plasma fibrinogen, nasal bacterial mean colony counts of pasteurella hemolytica and pasteurella multocida, total and differential leukoyte counts, packed cell volumes and the following, twice during the week: serum and nasal antibody titres to p. hemolytica and parainfluenza-3 virus. the lungs ... | 1975 | 164992 |
| the measurement of choline kinase activity in rat brain: the problem of alternate pathways of atp metabolism. | | 1975 | 165749 |
| glucose-induced proinsulin biosynthesis. role of islet cyclic amp. | | 1977 | 193750 |
| acute interstitial pneumonia [proceedings]. | | 1977 | 193807 |
| the storage lipids in tangier disease. a physical chemical study. | the physical states and phase behavior of the lipids of the spleen, liver, and splenic artery from a 38-yr-old man with tangier disease were studied. many intracellular lipid droplets in the smectic liquid crystalline state were identified by polarizing microscopy in macrophages in both the spleen and liver, but not in the splenic artery. the droplets within individual cells melted sharply over a narrow temperature range, indicating a uniform lipid composition of the droplets of each cell. howev ... | 1977 | 193870 |
| cellular hypersensitivity to basic myelin (p2) protein in the guillain-barré syndrome. | lymphocytes of 29 subjects were assayed for mif production in response to p2 peripheral nerve protein, crude human peripheral nerve and human central nervous system al basic myelin protein. seven were performed in normal control subjects, 12 in guillain-barre patients (gb), 5 with other polyneuropathies and 5 in patients with multiple sclerosis (ms). only gb patients with acute illness produced mif in response to neuritogenic p2 protein and crude human nerve. two ms patients in the acute phase o ... | 1975 | 165869 |
| presynaptic localization of opiate receptors in the vagal and accessory optic systems: an autoradiographic study. | | 1978 | 206855 |
| circular dichroism and circular polarization of luminescence of reduced nicotinamide adenine dinucleotide in solution and bound to dehydrogenases. | the cd (circular dichroism) and cpl (circular polarization of luminescence) spectra of nadph in aqueous solution were studied and found to be markedly different. the spectra were not affected by cleavage of the coenzyme molecule with phosphodiesterase. the differences are thus not due to the existence of extended and folded conformations of nadph and it is concluded that they originate in excited state conformational changes of the nicotinamide--ribose fragment. opposite signs of both the cd and ... | 1978 | 207311 |
| vaccination immunity to selected diseases in chickens fed the androgen analog mibolerone. | chickens fed the androgen analog mibolerone during the first 7 weeks of life regress their bursa of fabricius but can be properly immunized by vaccination against avian pathogens of major economic importance such as newcastle disease virus, infectious laryngotracheitis virus, avian encephalomyelitis virus, infectious bronchitis virus, fowl pox virus, marek's disease virus, and pasteurella multocida, the pathogen causing fowl cholera. these findings on immunocompetence to infectious agents are im ... | 1978 | 209430 |
| comparison of interferon action in interferon resistant and sensitive l1210 cells. | translation inhibition, leu-trna aminoacylation and double-stranded rna and atp dependent phosphorylation were examined in interferon-treated and control cell-free lysates of leukaemic mouse l 1210 r and l 1210 s cells. no differences were observed between the respective interferon-treated and control cell-free extracts, except for the presence of an enhanced 67k dalton phosphoprotein fraction in interferon-treated l 1210 s cell-free extracts. in non-responding cell-free lysates, the lack of sti ... | 1978 | 212514 |
| effect of polymyxin b sulfate on endotoxin activity in a gram-negative septicemia model. | the antiendotoxin effect of polymyxin b was investigated in experimentally induced septicemia in rabbits. the pasteurella multocida organisms were sensitive to the antibacterial action of penicillin but not to polymyxin b. animals pre-treated with polymyxin showed positive blood cultures and significantly reduced plasma endotoxin levels (limulus test) with normal white blood cell and platelet counts when analyzed 6 hr after the injection of live organisms. polymyxin therapy given after the anima ... | 1979 | 219410 |
| observations on outbreaks of respiratory disease in housed calves--(1) epidemiological, clinical and microbiological findings. | in 47 of 50 outbreaks of respiratory disease in indoor calves which had never been to grass there was clinical evidence of pneumonia in all animals examined. calf housing was in most cases considered unsatisfactory. virus activity was detected in 70 per cent of outbreaks investigated within a few days post onset of respiratory signs. parainfluenza (pi) 3 and respiratory syncitial virus (rsv) were the viruses most frequently involved. in the majority of outbreaks mycoplasma species and pasteurell ... | 1978 | 219582 |
| secretory granules of the duodenal enterochromaffin cells of the cat. | | 1979 | 222959 |
| respiratory virus infections in children hospitalized in montreal, 1968 - 1972. | | 1975 | 165872 |
| protein and glycoprotein electrophoretic patterns of enriched fractions of primary and secondary granules from guinea pig polymorphonuclear leukocytes. | the postnuclear supernatant fraction of sucrose homogenates of guinea pig polymorphonuclear leukocytes (pmnl) was subjected to differential centrifugation to obtain a total particulate fraction, a particle-free supernatant fraction, highly enriched fractions of primary and secondary granules, and a membrane-rich fraction. the various fractions were solubilized in buffer containing sodium dodecyl sulfate (sds) and analyzed for protein and glycoproteincomponents by sds -polyacrylamide gel electrop ... | 1975 | 166079 |
| cholinergic activity regulates muscarinic receptors in central nervous system cultures. | muscarinic acetylcholine receptor activation induces a loss of muscarinic receptors from cultured neuroblastoma and embryonic chicken cerebrum cells. as measured by specific binding of [3h]quinuclidinyl benzilate, steady-state receptor concentrations decrease 75% in response to receptor-saturating concentrations of cholinomimetic drugs. both the degree and duration of activation determine the extent of receptor loss. a method for analyzing receptor turnover, which does not rely upon protein synt ... | 1979 | 226997 |
| some major consequences of actions of drugs on the autonomic nervous system in man and experience of prediction from animal studies. | | 1979 | 227001 |
| photodynamic therapy for herpes simplex: a critical review. | | 1979 | 227002 |
| some aspects of corticosteroid-induced cleft palate: a review. | since the discovery 25 years ago that cortisone can produce cleft palate in mouse embryos investigations into possible mechanisms of this corticosteroid-induced defect have been many and varied. however, the teratogenic mode of action remains not fully clarified. it is with this thought in mind that we have reflected upon what is known concerning corticosteroids and cleft palate. the major metabolic pathways upon which glucocorticoids act as well as their intracellular mode of action are well kn ... | 1975 | 166456 |
| a radioimmunoassay for hepatitis a antigen and antibody. | the havab radioimmunoassay for the detection of antibody to hepatitis a is assessed. its modification to detect virus in faecal samples is described and in this it was found to be more sensitive and specific than electron microscopy. | 1979 | 227943 |
| relationship between epstein-barr virus-associated nuclear antigen and cell viability in human cell lines. | the relationship between the cell viability and frequency of cell with epstein-barr virus (ebv)-associated nuclear antigen was investigated in cultures of 4 ebv-carrier lymphoblastoid cell lines, by means of anti-complement immunofluorescence. the percentages of viable cells and those of eb nuclear antigen-positive cells were close to each other in the entire course of cultivation of all cell lines. this leads to a conclusion that absence of eb nuclear antigen in a given cell population should b ... | 1975 | 168112 |
| functional consequences of modifying highly reactive arginyl residues of fructose 1,6-bisphosphatase. loss of monovalent cation activation. | modification of pig kidney fructose 1,6-bisphosphatase with 2,3-butanedione (in the presence of amp) results in the loss of activation of the enzyme by monovalent cations. under these conditions about 8 arginyl residues per mole of enzyme were modified. no other residues were modified. no loss of monovalent cation activation occurs when modification with 2,3-butanedione is carried out in the presence of amp plus the substrate fructose 1,6-bisphosphate and 3.2 less arginyl residues were modified. ... | 1975 | 169892 |
| ascorbate increases the synthesis of procollagen hydroxyproline by cultured fibroblasts from chick embryo tendons without activation of prolyl hydroxyla. | an improved procedure was developed to extract prolyl hydroxylase from tendon cells of chick embryos with detergent, and improved assays were developed for both the activity of the enzyme and the amount of enzyme protein. freshly isolated tendon cells were found to contain approx. 100 mug of enzyme protein per 10(8) cells and 40-50% of the enzyme protein was active. when the cells were cultured, they were found to contain the same amount of enzyme protein but only 15-20% of the enzyme protein wa ... | 1975 | 172137 |
| the estrogen cytosol receptor of female ovine pituitary. | the biochemical parameters of estrone and estradiol binding to the cytosol fraction of ovine anterior pituitary were investigated. when increasing amounts of [3h]estrone or [3h]estradiol were incubated with the 105,000 g fraction from the pituitary, both hormones bound to a receptor with the same apparent kd (mean +/- s.e., estrone = 1.40 +/- 0.30 x 10(-10) m, estradiol = 1.03 +/- 0.11 x 10(-10)m) and the same concentration of binding sites (estrone = 3.22 +/- 0.58 x 10(-14) moles/mg protein, es ... | 1975 | 172395 |
| peritonitis due to pasteurella multocida in a rabbit. | | 1979 | 255014 |
| feline eosinophilic granuloma complex: a clinicoepidemiologic study of 32 cases. | | 1979 | 257955 |
| cats in the cubicle. | | 1979 | 259262 |
| lamb trauma caused by porcupine grass (stipa spartea) seeds. | | 1979 | 261008 |
| experimental studies on the biological properties of bordetella pertussis. | | 1979 | 262507 |
| reduction of testosterone to 5 alpha-dihydrotestosterone by human and rat uterine tissues. | incubations of adult rat uterine tissue and human endometrial and myometrial homogenates with [1,2,6,7-3h]testosterone resulted in the formation of 5 alpha-[3h]dihydrotestosterone. the rat uterine homogenates showed higher activity than the minced tissue. the activity in human tissue was found to be less than rat tissue on a per unit weight basis. the human endometrium has been found to possess significantly higher activity than myometrium. these results support the hypothesis that androgens may ... | 1978 | 262766 |
| reconstitution of bacillus stearothermophilus 50 s ribosomal subunits from purified molecular components. | bacillus stearothermophilus 50 s ribosomal subunits have been reconstituted from a mixture of purified rna and protein components. the protein fraction of 50 s subunits was separated into 27 components by a combination of various methods including ion exchange and gel filtration chromatography. the individual proteins showed single bands in a variety of polyacrylamide gel electrophoresis systems, and nearly all showed single spots on two-dimensional polyacrylamide gels. the molecular weights of ... | 1976 | 172511 |
| genetic and physiological studies on the relationship between colicin b resistance and ferrienterochelin uptake in escherichia coli k-12. | the escherichia coli gene for the ferrienterochelin uptake and colicins b and d receptor protein is located at approximately 13 min, adjacent to or among genes for enterochelin biosynthetic enzymes. the two receptor functions (colicin and siderophore) are separable by mutation. | 1979 | 153899 |
| synthesis of fibroma viral deoxyribonucleic acid complexes in rabbit kidney cells. | cytoplasmic extracts of primary rabbit kidney cells inoculated with fibroma virus revealed 2 peaks of dna complexes (120s and greater than or equal to 410s) in a linear sucrose gradient. pulse-chase experiments demonstrated a shift in the gradient profile of lighter complexes toward heavier complexes. synthesis of dna complexes was inhibited by adding puromycin or actinomycin d. the dna from virus-infected cultures hybridized 7 to 9 times greater with fibroma virus dna than did the dna from noni ... | 1975 | 173213 |
| type-c rna viruses of the nih nude mouse. | several types of tumors from various species were propagated in nih athymic nude mice. subsequently, cell lines were established from the tumors and examined for evidence of type-c virus activity. hybrid mice (nih swiss and balb/c) harbored murine type-c viruses of three categories: n-tropic, b-tropic and x-tropic. | 1975 | 173863 |
| comparison of ilium to rib for bone grafting in defects of canine mandibular alveolar fidge. | the behavior of iliac and rib grafts in surgically created defects in canine alveolar ridges was investigated. despite the greater amount of potentially osteogenic tissue in the iliac graft, no significant qualitative differences were noted in the bony remodeling for a year. however, the rib grafts did form a mature superior cortical border significantly more rapidly, leading to speculation on the advantages of rib over iliac graft in alveolar ridge grafting. | 1977 | 270564 |
| induction of human cell dna synthesis by herpes simplex virus type 2. | the effect of herpes simplex virus type 2 (hsv-2) infection on the synthesis of dna in human embryonic fibroblast cells was determined at temperatures permissive (37 c) and nonpermissive (42 c) for virus multiplication. during incubation of hsv-2 infected cultures at 42 c for 2 to 4 days or after shift-down from 42 to 37 c, incorporation of (3h)tdr into total dna was increased 2-to 30-fold as compared with mock-infected cultures. analysis of the (3h)dna suggested that host cell dna synthesis was ... | 1975 | 163370 |
| translation of the genes for the structural proteins of alphaviruses. | synthesis of the structural proteins of semliki forest virus by a cell-free system derived from mouse l-cells and programmed by intracellular 26s rna is described. this polycistronic rna is translated in vitro into several discrete polypeptides. the identity of these polypeptides as the structural proteins of the virus was established by polyacrylamide gel electrophoresis, immunoprecipitation and tryptic peptide mapping. studies using formyl--e135s]methionyl-trnaf as precursor, and using diphthe ... | 1975 | 173941 |
| [different pathogenic power of the original bcg strain of the pasteur institute and of an isoniazid resistant strain. histopathological study and significance of local abscesses after inoculation of guinea pig]. | the inoculation into guinea pigs of 10 mg of bcg, obtained either from the pasteur institute original strain, or from a mutant isoniazid resistant strain, b1 catalase positive, caused in 40.4% of cases, the onset of abscesses at the point of injection. the frequency and course of these abscesses appear quite different with the two strains, 92.8% with the classical strain, persisting in more than half of the cases after one year, and 23.5% with the inh-resistant strains which regressed within 6 m ... | 1975 | 174202 |
| epstein-barr virus in an american patient with burkitt's lymphoma: detection of viral genome in tumor tissue and establishment of a tumor-derived cell line (nab). | epstein-barr virus (ebv) dna (17.7 genome equivalents/cell) was found in tumor tissue from an american patient with burkitt's lymphoma who had never traveled outside the united states. a lymphoid cell line (nab) containing the ebv genome was established from tumor tissue from this patient; characteristics of this cell line were described. previous burkitt's tumors found in americans and examined by molecular hybridization were negative for ebv dna. our results suggested that ebv is associated wi ... | 1976 | 176407 |
| stepwise transition of aggregate structure of high-molecular-weight avian myeloblastosis virus rna. mode of releasing of associated 4s rna. | mode of releasing of associated 4s rna species was studied during a controlled transition of aggregate structure of high-molecular-weight amv-rna. it has been found that associated 4s rna constitutes 2.5% of 60s amv-rna complex. approximately 60% of associated 4s rna is successively released during treatment of viral rna with increasing formamide concentration, concomitantly with the transition of 60s rna aggregate through 50--55s rna intermediate into the final 30--40s rna subunits. 40% of 4s r ... | 1976 | 180440 |
| pasteurella multocida septicemia. | | 1979 | 293515 |
| [rheumatic manifestations in infections caused by mycoplasma and pasteurella multocida]. | | 1977 | 302974 |
| further studies on the neonatal ferret model of infection and immunity to and attenuation of human parainfluenza viruses. | earlier we reported on the susceptibility via the intranasal route of inoculation of newborn ferrets to infection by wild and serially egg passaged parainfluenza type 3 virus. the wild type consistently induced fatal infection whereas with serial egg passage, mortality rate decreased while the degree of infectivity remained the same. this attenuation was accompanied by a change in capacity to induce interferon and decreased growth in human and primate cell cultures. the present work reports, sim ... | 1976 | 182598 |
| induction in b2/b2 chickens of immunity to transplantable carcinogen-induced fibrosarcomas mediated by t-cell monocyte cooperation: role of delayed hypersensitivity to unrelated antigens. | | 1977 | 303451 |
| genetic control of the content and avidity of hapten-binding b lymphocytes in mouse spleen. | | 1978 | 308926 |
| demonstration of antinuclear antibodies in mercuric chloride-induced glomerulopathy in the rat. | serial administration of mercuric chloride to pvg/c rats induced a glomerulopathy associated with immune complex deposition along the glomerular basement membrane and in the mesangial area. these deposits could be demonstrated by immunofluorescence and electron microscopy 5 to 8 weeks after the first injection of mercuric chloride. at this time antinuclear antibodies could be demonstrated in the sera and in the eluates from the renal cortices from diseased animals. these findings suggest a possi ... | 1978 | 309027 |
| apparatus for uniaxial testing of soft human tissues in vitro. | | 1978 | 309051 |
| inflammatory cells in solid murine neoplasms. i. tumor disaggregation and identification of constituent inflammatory cells. | mechanical and enzymatic methods of disaggregating tumors were studied with the goals of (1) minimizing cell losses while (2) maintaining functional and surface membrane markers needed to objectively identify inflammatory cells (ic)1 in resultant suspensions. application of the principles and methods described makes accurate estimation of the percentage of each ic type present in neoplasms possible for the first time. compared to purely mechanical means of disaggregating tumors, all enzyme mixtu ... | 1976 | 182647 |
| blood pressure in unanesthetized bacterially infected rabbits: effects of antipyretic drug therapy. | it has previously been determined that an intraperitoneal infusion of a combination of antipyretic-anti-inflammatory drugs, sodium salicylate and acetaminophen, increases the survival rate of rabbits injected with pasteurella multocida, a gram-negative bacterium. to determine whether the increased survival rate was attributable to antihypotensive effects of the drug therapy, aortic arch blood pressure was measured continuously in unanesthetized rabbits before and after an injection of bacteria. ... | 1979 | 313283 |
| comparison of the virulence of o:9,12 and o:4,5,12 salmonella typhimurium his+ transductants for mice. | the purpose of these experiments was to determine whether qualitative differences in the o repeat unit of the lipopolysaccharide of pathogenic salmonella species affected virulence for mice. o:4,5,12 and o:9,12 sister his+ transductants were derived from a virulent salmonella typhimurium. fermentation markers were introduced by transduction to differentiate these strains, and the strains were used as mixed challenge to cf1 and c57b1/6j mice. liver and spleen cultures of the mice of various inter ... | 1977 | 321351 |
| properties of trna-specific antibodies from nzb/nzw mice. | antibodies that bind trna are produced spontaneously in new zealand black/new zealand white (nzb/nzw) f1 hybrid female mice. an assay for the detection of these antibodies has been developed by using gel filtration and radioactive trna. this assay was found superior to the widely used ammonium sulfate precipitation assay because of the nature of the interaction between the protein and the trna. the ant-bodies bound native trna preferentially to trna denatured by cross-linking with formaldehyde. ... | 1977 | 321680 |
| [chemically defined and partially defined media for pasteurella multocida and pateurella hemolytica]. | two culturing recipes were suggested for pasteurella multocida and pasteurella haemolytica, one partialy defined nutritive defined nutritive medium with 0.5 per cent yeast extract and one chemically defined medium. both had been composed on the basis of studies into nutrient demand and into the effects of complex nutritive substrates. both nutritive media are applicable also to culturing other bacterial species. (among the strains tested so far were streptococci, staphylococci, escherichia coli, ... | 1977 | 322633 |
| cross-reactive antigens: their potential for immunization-induced immunity to gram-negative bacteria. | the involvement of multiple species and serologic types in gram-negative bacteremia prompted evaluation of immunization with shared, cross-reactive antigens of gram negative bacilli. active and passive immunization with re chemotype mutants of salmonella minnesota afforded significant protection against heterologous gram-negative bacilli and were considerably more effective than immunization with smooth s. minnesota or its ra, rb, rc, rd1 and rd2 mutants. since the lipopolysaccharide of the re m ... | 1977 | 330775 |
| ultrastructural cytology of prostate carcinoma cells from wistar rats. | cells from spontaneous adenocarcinomas of the prostate (pollard, m.: j. natl. cancer inst. 51: 1235, 1973) in aged lobund wistar rats were examined by electron microscopy. cytologic structures of the rat prostate tumor cells resembled analogous structures from human prostate tumor cells. these findings support the prospect that the rat prostate tumor will provide a model system of prostate cancer in man. | 1976 | 184062 |
| crystallization and crystallographic data of escherichia coli maltodextrin phosphorylase. | | 1978 | 340270 |
| the release of endogenous amino acids from the rat visual cortex. | the release of endogenous taurine, gaba, glycine, aspartate, glutamate, glutamine and alanine from the rat visual cortex was measured using a cortical cup technique. the electrocorticogram (ecog) was monitored throughout most experiments. 2. spreading depression, evoked by the dropwise placement of 10% kcl solution on to the brain outside the cup was associated with a significant increase in the release of gaba and glutamine but a marked fall in that of glutamate. the evoked release of gaba and ... | 1976 | 186588 |
| marine cardioactive agents. adenosine and 2'-deoxyadenosine from dasychalina cyathina. | | 1978 | 362107 |