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pharmacokinetics of penicillin g in the turkey.parmacokinetics of penicillin g was determined for the turkey. the study was prompted by the isolation of a sulfonamide-resistant strain of pasteurella multocida from tissues of turkeys involved in an outbreak of fowl cholera and the subsequent discovery that little pharmacologic information was available concerning other antimicrobial agents in that species. penicillin g was chosen for study because p multocida is susceptible to this antibiotic. the elimination of the antibiotic followed first- ...1978677541
a case report of total knee arthroplasty infected by pasteurella multocida.a 72-year-old woman with a total knee prosthesis was infected with pasteurella multocida organisms from a cat bite. the joint was successfully salvaged by surgical debridement, closed tube irrigation utilizing .25% acetic acid and appropriate antibiotics.1978679534
effect of bursectomy and thymectomy on pasteurella multocida infection in chickens.the effects of various treatments on the immune response of chickens to vaccine prepared from pasteurella multocida strain p1059 were investigated. the treatments, given on or before the day of hatching, consisted of surgical bursectomy (sb), hormonal bursectomy (hb), surgical thymectomy (st) and x-irradiation (x). in chickens subjected to sb, sbx or hb before vaccination, the production of agglutinin and immunoglobulin was impaired, but the production of resistance against challenge was not. in ...1978682178
[contamination and age as factors in the pathogenesis of atrophic rhinitis (author's transl)].the relationship between contamination with bordetella bronchiseptica or pasteurella multocida and the age of the piglets on the one hand and the pathogenesis of atrophic rhinitis on the other, is discussed. minimal disease-free piglets born and reared on farms on which pigs affected with clinical atrophic rhinitis were present, developed clinical atrophic rhinitis at the age of six weeks. piglets born in the central veterinary institute (cvi) of sows from herds including pigs affected with atro ...1978684734
pasteurella multocida infectious arthritis.pasteurella multocida, a small gram-negative rod, is a domestic animal saprophyte that occasionally causes disease in humans. infectious arthritis may develop from a superficial animal bite or scratch. nine previous cases of infectious arthritis due to this organism have been documented in the literature, and a tenth case is reported here. most patients had recent animal exposure, and half the patients had underlying chronic rheumatoid arthritis. clinical signs of inflammation were consistently ...1978686043
an agglutination test for the detection of bordetella bronchiseptica infection in swine.an agglutination test with the use of formalin-killed antigen of the cell carrying the capsule was developed and used for the detection of antibody in swine naturally infected with bordetella bronchiseptica. under optimum antigen concentration and reaction temperature 210 or 60% of 342 serum samples tested from 42 conventional swine herds were positive for bordetella infection. in contrast, only 34 or 10% of 342 nasal swabs from the same animals were positive for bordetella by culture technique. ...1978688071
the january 1977 avian cholera epornitic in northwest california.a total of 844 birds were observed dead at three sites in humboldt county and an estimated 6750 birds died at three sites in del norte county, california. coots were the primary species affected. the isolation of pasteurella multocida from a snowy egret (egretta thula) is the first reported case of avian cholera in this bird. there was evidence for a distinct sequence in the bird species dying at one site; american coots (fulica americana) appeared to be the first species to die.1978691123
pasteurella multocida from canine and feline teeth, with a case report of glossitis calcinosa in a dog caused by p. multocida.a case of glossitis calcinosa in a dog caused by pasteurella multocida is reported. swelling of the tongue and reduced appetite were the predominant clinical symptoms. due to latent infections with p. multocida in many species there is a risk of bitewounds being infected with this microorganism. in order to find the carrier-rate of p. multocida samples in canines, teeth and gingiva of 121 dogs and 30 cats were examined bacteriologically, revealing a carrier rates of 55% and 80% respectively. the ...1978693275
[atrophic rhinitis in swine].four 60-day-old pigs were experimentally infected with bordetella bronchiseptica at a state in which the animals were clinicylly normal. a single pig only, killed on the 180th day, presented a slight deflection of septum nasi. morphologically, there were severe dystrophic and necrotic changes in the mucosa of the conchae, the nasal cartilages as well as in the bones. the pathogen was reisolated from two of the pigs. clinical and morphological investigations were carried out also with spontaneous ...1978706148
crystallization and crystallographic data of escherichia coli maltodextrin phosphorylase. 1978340270
marine cardioactive agents. adenosine and 2'-deoxyadenosine from dasychalina cyathina. 1978362107
comparison of effects of dietary t-2 toxin on growth, immunogenic organs, antibody formation, and pathologic changes in turkeys and chickens.the effect of t-2 toxin (trichothecene mycotoxin) consumption on broad-breasted white turkey poults and white leghorn chicks was studied. groups of ten 8-day-old poults were fed rations containing t-2 at 10 ppm, 2ppm, or 0 ppm (controls) for a period of 4 weeks; a 4th group (inanition control) was fed control rations equal to the amount consumed by the group fed rations containing t-2 at 10 ppm during the previous 24 hours. a similar experimental design was used to study the effect of the toxin ...1978362995
studies on pasteurella multocida. vii. dynamics and temporal development of local humoral immunity induced by a live avirulent fowl cholera vaccine.vaccination of turkeys by administering the cu strain of pasteurella multocida in drinking water induced local antibodies in the tracheal secretions. their appearance and persistence were demonstrated by the indirect immunofluorescence technique. local antibodies were induced by the 10th day and persisted up to the 42nd day postvaccination, whereas none were induced by an oil-adjuvanted bacterin throughout the observation period (56 days). thus, the cu strain of p. multocida appeared to generate ...1978373744
ultrastructure of 1,2-dimethylhydrazine-induced adenocarcinomas in rat colon. 1978280713
osteomyelitis of the tibia following dento-alveolar abscess. a case report. 1978281235
genetic control of the content and avidity of hapten-binding b lymphocytes in mouse spleen. 1978308926
a bactericidal substance against pasteurella multocida produced by pig embryo tracheal explants. 1978286393
[fibrous suppurative arthritis in sheep].described are cases of fibrinous supprative arthritis in sheep characterized by thickenning of the joint, resulting from the involvement of the capsule (periarthritis). histopathologically, there have been suppurative and necrotic processes combined with fibrinoid necrotizing of the collagen fibers and leukocyte infiltration of the joint capsule. slight leukocyte infiltration has also been said to occur in the parenchymal organs. microbiologic studies have revealed the presence of pyogenous bact ...1978369111
observations on outbreaks of respiratory disease in housed calves--(1) epidemiological, clinical and microbiological findings.in 47 of 50 outbreaks of respiratory disease in indoor calves which had never been to grass there was clinical evidence of pneumonia in all animals examined. calf housing was in most cases considered unsatisfactory. virus activity was detected in 70 per cent of outbreaks investigated within a few days post onset of respiratory signs. parainfluenza (pi) 3 and respiratory syncitial virus (rsv) were the viruses most frequently involved. in the majority of outbreaks mycoplasma species and pasteurell ...1978219582
apparatus for uniaxial testing of soft human tissues in vitro. 1978309051
a microangiographic study of vascular changes in replanted and autotransplanted teeth of young dogs.the purpose of the present investigation was to study the revascularization process of the pulp of replanted and autotransplanted teeth with incomplete root development in dogs. a barium-sulfate injection method combined with contact microradiography was used. ingrowth of apparently new vessels was seen during the first postoperative days. after 10 days, visible vessels were seen in the apical half of the pulp, and after 30 days, in the whole pulp. branches and apparently also anastomoses betwee ...1978271284
direct activation of complement by trypanosomes. 1978351160
demonstration of antinuclear antibodies in mercuric chloride-induced glomerulopathy in the rat.serial administration of mercuric chloride to pvg/c rats induced a glomerulopathy associated with immune complex deposition along the glomerular basement membrane and in the mesangial area. these deposits could be demonstrated by immunofluorescence and electron microscopy 5 to 8 weeks after the first injection of mercuric chloride. at this time antinuclear antibodies could be demonstrated in the sera and in the eluates from the renal cortices from diseased animals. these findings suggest a possi ...1978309027
circular dichroism and circular polarization of luminescence of reduced nicotinamide adenine dinucleotide in solution and bound to dehydrogenases.the cd (circular dichroism) and cpl (circular polarization of luminescence) spectra of nadph in aqueous solution were studied and found to be markedly different. the spectra were not affected by cleavage of the coenzyme molecule with phosphodiesterase. the differences are thus not due to the existence of extended and folded conformations of nadph and it is concluded that they originate in excited state conformational changes of the nicotinamide--ribose fragment. opposite signs of both the cd and ...1978207311
vaccination immunity to selected diseases in chickens fed the androgen analog mibolerone.chickens fed the androgen analog mibolerone during the first 7 weeks of life regress their bursa of fabricius but can be properly immunized by vaccination against avian pathogens of major economic importance such as newcastle disease virus, infectious laryngotracheitis virus, avian encephalomyelitis virus, infectious bronchitis virus, fowl pox virus, marek's disease virus, and pasteurella multocida, the pathogen causing fowl cholera. these findings on immunocompetence to infectious agents are im ...1978209430
presynaptic localization of opiate receptors in the vagal and accessory optic systems: an autoradiographic study. 1978206855
comparison of interferon action in interferon resistant and sensitive l1210 cells.translation inhibition, leu-trna aminoacylation and double-stranded rna and atp dependent phosphorylation were examined in interferon-treated and control cell-free lysates of leukaemic mouse l 1210 r and l 1210 s cells. no differences were observed between the respective interferon-treated and control cell-free extracts, except for the presence of an enhanced 67k dalton phosphoprotein fraction in interferon-treated l 1210 s cell-free extracts. in non-responding cell-free lysates, the lack of sti ...1978212514
reduction of testosterone to 5 alpha-dihydrotestosterone by human and rat uterine tissues.incubations of adult rat uterine tissue and human endometrial and myometrial homogenates with [1,2,6,7-3h]testosterone resulted in the formation of 5 alpha-[3h]dihydrotestosterone. the rat uterine homogenates showed higher activity than the minced tissue. the activity in human tissue was found to be less than rat tissue on a per unit weight basis. the human endometrium has been found to possess significantly higher activity than myometrium. these results support the hypothesis that androgens may ...1978262766
influence of some divalent cations on heart sarcolemmal bound enzymes and calcium binding. 1978153143
[immunoprofile of lmif in immunologic deficiency syndromes. ii. mediator production by isolated subpopulations of human lymphocytes]. 1978149303
[on the connections between the rami communicantes of the sympathicus and the rami posteriores of the loin nerves (author's transl)].the existence of anastomoses between the rami communicantes of the truncus sympathicus and the rami posteriores of the loin nerve in man has been confirmed macroscopically and microscopically in 50% of the cases. this is followed by a discussion of the causality of pains in the loin region.1978150806
[raised prostaglandin e-2 level in focal inflammatory lesions of the human skin with particular reference to rosacea]. 1978151301
solubilization and partial purification of prostaglandin endoperoxide synthetase of rabbit kidney medulla.the microsomes of rabbit kidney medulla converted arachidonic acid into prostaglandin e2 in the presence of hemoglobin, tryptophan and glutathione as activators. when themicrosomal suspension was treated with 1% tween 20, a solubilized enzyme was obtained which catalyzed the conversion of arachidonic acid to prostaglandins g2 and h2. the solubilized enzyme was adsorbed to and then eluted from an omega-aminooctyl sepharose 4b column, resulting in about 10-fold purification over the microsomes. th ...197896862
chromosomal aberrations and congenital heart diseases.the incidence of chromosomal aberration with chd is 10.5% in the autopsy cases. 2. the characteristic major cardiac malformations associated with chromosomal aberration are conal abnormality, abnormal septation and cardiac valve abnormalities. 3. the characteristic association of chromosomal aberration and chd is cavo in down syndrome, triple shunts and multivalvular disease in 18 trisomy, shunts in delition syndrome and coarctation of the aorta in turner syndrome. 4. minor cardiac anomalies ass ...1978153412
the fourth volhard lecture: cardiovascular structural adaptation; its role in the initiation and maintenance of primary hypertension. 1978153216
laparoscopic examination of the reproductive tracts of gilts using a special crate.a crate for restraining gilts for routine laparoscopic examination of the reproductive tract is described, together with the techniques employed in anaesthesia and laparoscopy. the procedure is efficient, allowing two operators to examine 4-5 gilts per hour.1978148883
[sarcocyst resistance to certain factors]. 197897852
the metabolism and disposition of 3,4,4'-trichlorocarbanilide in the intact and bile duct-cannulated adult and in the newborn rhesus monkey (m. mulatta). 1978106490
chelation in metal intoxication. vi. influence of pas and cdta on the excretion of manganese in rabbits given mno2.the success of p-aminosalicyclic acid (pas) and 1,2-cyclohexylene dinitrilotetraacetic acid (cdta) in the mobilization of manganese from some vital organs and their subcellular fractions of manganese-intoxicated rats, led to the two compounds beng further investigated individually and in combination for their efficacy in influencing excretion of manganese in rabbits given mno2. these chelating agents led to a higher excretion of manganese through faeces than urine. whereas cdta was able to enhan ...197896549
[phenotypic expression of colon polymorphic antigens (wz) in human colon adenocarcinomas].human colon adenocarcinomas from 52 patients were investigated for the presence of the colon polymorphic antigens wz. the patients were typed for their wz phenotype, using the immunofluorescence method on non tumoral colon mucosa sections: 27 patients were found w+ z+, 18 w- z+, and 7 w- z-. the tumors were tested for the presence of the wz phenotypes, using the immunofluorescence method and a radio-immunoassay. the wz phenotypes were not expressed in the non secreting tumors, whatever the patie ...197897030
[personal prophylaxis of venereal diseases]. 197897875
carrier rate of pasteurella multocida in a cattle herd associated with an outbreak of haemorrhagic septicaemia in the sudan. 197898205
synergism between morphogenetic mutants of myxococcus xanthus. 197898366
immunopathology of malaria. 197898476
pleiotropic effect of a rifampin-resistant mutation in bacillus subtilis.rifampin-resistant (rifr) mutants were isolated spontaneously from bacillus subtilis strain 168. a fraction of the mutants did not grow on a minimal medium. a high concentration of one of the l-amino acids (glutamic acid, glutamine, arginine, proline, aspartic acid, or asparagine) was required to restore their growth on the medium. further analysis of one of the mutants (strain rf 161) suggested that the mutant is unable to use ammonia as a nitrogen source and requires amino acids instead. activ ...197898517
evidence that the regulation of diphtheria toxin production is directed at the level of transcription.it has been known for several decades that iron inhibits the production of diphtheria toxin by corynebacterium diphtheriae by preventing expression at maximal levels. we examined the inhibition kinetics of toxin production after the addition of either iron or rifampin to iron-limited cultures of c7 (betatox+). iron-mediated inhibition of toxin production was found to be linear within the range of 16 nm to 16 micron. the inhibition kinetics following the addition of iron or rifampin was almost id ...197898519
in vitro antibacterial activity of amikacin and ticarcillin, alone and in combination, against pseudomonas aerurginosa.in vitro antimicrobial susceptibility studies using amikacin and ticarcillin, alone and in combination, were performed on 20 strains of pseudomonas aeruginosa. all strains were susceptible to amikacin, and ticarcillin was active against 16 of the 20 strains. enhanced anti-pseudomonas activity could be demonstrated with the combination of amikacin and ticarcillin.197898109
dipeptidylaminopeptidase and carboxypeptidase activities of the brush border of rabbit small intestine. 197830675
[sensitivity of bordetella bronchiseptica, pasteurella multocida and mycoplasma hyorhinis strains isolated from pigs towards antibiotics and chemotherapeutic agents]. 1978100928
jaundice and breast-feeding among alaskan eskimo newborns.the course, incidence, and severity of neonatal jaundice was studied in 95 alaskan eskimo infants. breast-fed infants had higher bilirubin concentrations than bottle-fed babies. both groups experienced high bilirubin levels, similar to those previously reported in navajo and oriental infants but greater than those observed in whites and blacks. a marked capacity to inhibit hepatic glucuronyl transferase was observed in breast-milk specimens but only partly accounted for the bilirubin differences ...197899026
[transplantation of langerhans' islands]. 197899549
coagglutination test for identification of pasteurella multocida associated with hemorrhagic septicemia.two serogroups (b and e) of pasteurella multocida associated with hemorrhagic septicemia in cattle were differentiated by a coagglutination test with antibody-coated staphylococci. the group antigen was soluble and heat stable. it was not detectable in unencapsulated cells or their heated extracts. adsorbed onto human type o erythrocytes, it could be demonstrated by an indirect hemagglutination test with specific antiserum or by coagglutination with specific antibody-coated staphylococci. antibo ...197881214
[transplantation of the big toe from the foot to the hand in monkeys using a microsurgical technic]. 197897465
effects of pelleting and sterilization of diet on 2 strains of rabbit coccidia.both autoclaving and irradiation at levels currently used for other laboratory animal diets appear to be satisfactory for the elimination of 2 of the most robust and pathogenic species of rabbit coccidia. pelleting by the usual methods, even at 68 degrees c, was found to be unsatisfactory in eliminating all oocysts from heavily infected diet.197897471
[evaluation of the immune state of poultry against newcastle virus via various serological reactions].studied were 336 sera of vaccinated and challenged chickens, 76 egg extracts, and 36 birds following challenge for the presence of serum antibodies against the newcastle disease virus, using the hemagglutination-inhibition reaction, the agar gel diffusion precipitation reaction, and the virus-neutralizing test. the values of the antihemagglutinins, precipitins, and virus-neutralizing antibodies were investigated in relation to the immunobiologic resistance of birds to a velogenic newcastle disea ...1978105460
experimental spinal cord trauma, ii: blood flow, tissue oxygen, evoked potentials in both paretic and plegic monkeys.graded clinical motor deficits were produced in a series of rhesus monkeys subjected to experimental spinal cord trauma from a variety of impact loads. an argon washout technique was used to measure spinal cord blood flow; tissue oxygen carbon dioxide, and somatosensory evoked potentials (seps) were also monitored. each animal received a clinical grade and, after a week of study, the spinal cords were removed for histopathological grading. blood flow in paraplegic animals was significantly decre ...197898856
medical and surgical approach to laryngeal air sacculitis in a baboon caused by pasteurella multocida.air sacculitis was diagnosed in a chronically chaired baboon, papio anubis. pasteurella multocida was repeatedly isolated from the air sac for a period of 1 year. the condition was characterized by the continuous accumulation of either mucoserous or purulent fluid. biopsies of the air sac taken during the course of the disease initially revealed goblet cell hyperplasia. later a subepithalial mononuclear or polymorphonuclear infiltrate and necrosis was the predominate finding. medical therapy was ...1978108467
[the role of the culture medium in the sensitivity of gram-negative stocks and their resistant mutants to fosfomycin. the influence of glucose-6-phosphate]. 1978105326
in vivo regulation of glycolysis and characterization of sugar: phosphotransferase systems in streptococcus lactis.two novel procedures have been used to regulate, in vivo, the formation of phosphoenolpyruvate (pep) from glycolysis in streptococcus lactis ml3. in the first procedure, glucose metabolism was specifically inhibited by p-chloromercuribenzoate. autoradiographic and enzymatic analyses showed that the cells contained glucose 6-phosphate, fructose 6-phosphate, fructose-1,6-diphosphate, and triose phosphates. dithiothreitol reversed the p-chloromercuribenzoate inhibition, and these intermediates were ...1978101523
heterologous radioimmunoassay for rabbit prolactin.a highly specific heterologous double-antibody ria has been developed to measure rabbit prl by using guinea pig antiserum to human prl and ovine [125 i]iodo-prl. rabbit pituitary prl and serum give parallel dose-response curves in the assay and no cross-reaction (less than 0.1%) occurs with gh, placental lactogens, lh, fsh, or tsh from several different species. the assay is suitable for the measurement of human, ovine, bovine, caprine, and canine prl in addition to rabbit prl, but shows no cros ...1978105878
thyroid-stimulating hormone: neuroregulation and clinical applications. part 2. 197898254
a macrophage chemotactic factor sharing common antigenicity with immunoglobulin g from dnp-ascaris extract-induced skin lesion in guinea-pig.a macrophage chemotactic factor (factor a) was extracted from dnp-ascaris extract-induced skin lesions (showing a maximal macrophage reaction) in guinea-pigs and then purified by gel filtration on sephadex g-100 and chromatography using deae-sephadex and cm-sephadex. this material was a thermolabile protein (free of nucleic acid) with a molecular weight of about 150,000. it shared commom antigenicity with serum igg, and its chemotactic acitivity was completely absorbed by anti-igg and anti-light ...197898903
development of leucocytozoon caulleryi in chick embryos infected by biting of culicoides arakawae through shell membrane.chick embryos were infected with leucocytozoon caulleryi by biting of the midge, culicoides arakawae, through the shell membrane. schizonts of l. caulleryi were detected in the chorioallantoic membrane and most of the internal organs of embryos and of chicks after hatching. the development of schizonts was slower in embryos than in chickens. soluble antigens of l. caulleryi were demonstrated by the precipitation test in the allantoic fluid and blood from the embryos and chicks. no erythrocytic s ...197899671
blood groups of macaques:a comparative study.distribution of the human-type and of the simian-type blood groups in rhesus, crab-eating, bonnet, pig-tailed and stump-tailed macaques revealed significant similarities and differences among these species. human-type a--b-o blood groups cut across taxonomic lines and seem less value for taxonomic purposes than the simian-type blood groups detected by cross-reacting isoimmune rhesus monkey sera.1978101667
a comparison of tissue gold levels in guinea-pigs after treatment with myocrisin injected intramuscularly and triethylphosphine gold chloride and myocrisin administered orally.a comparative study of tissue gold levels produced in guinea-pigs after the oral administration of either triethylphosphine gold chloride or myocrisin (sodium aurothiomalate) or after the injection of myocrisin intramuscularly is reported. gold concentrations were determined 5, 24 and 168 hours after administration in stomach, small intestine, large intestine, kidney, liver and spleen and 5 and 24 hours after administration in skin, adrenals, heart, lung and brain. in gastrointestinal tissues, t ...1978102133
blood-brain barrier opening by isotonic saline infusion in normotensive and hypertensive animals.the blood-brain barrier to intravascular evans blue-albumin was opened in monkeys and rabbits by infusing isotonic saline for 15 s into the common carotid artery, when the external carotid was clamped temporarily and the lingual was catheterized for measuring pressure. barrier opening correlated better with infusion pressure than with infusion rate, and occurred at carotid artery pressures above 170 mmhg. systemic hypertension induced by aramine increased barrier vulnerability by causing a highe ...1978104549
effect of spa waters from the hisar health resort springs "momina banja" and "momina salza" on experimentally induced gastric ulcer. 1978104904
[determination of antigen structures of pasteurella multocida: the preparation of vaccines].the discovery of the role played by somatic antigens of the pasteurella multocida a and d capsular types in the immunization of susceptible species makes it necessary to type the somatic antigens of the isolated strains prior to any action to induce active or passive immunity. only immunoprecipitation in gel was chosen out of the various typing techniques proposed, and a correlation was established between the capsular types (according to carter), somatic types (according to namioka) and types d ...197889055
oligosaccharides and polysaccharides specifically utilizable by bifidobacteria. 1978103638
antigenic relationship between influenza c viruses.the object of this study was to determine whether antigenic groupings exist among influenza c viruses. altogether seven influenza type c strains were examined by reciprocal haemagglutination-inhibition and serum neutralization tests with sera produced in ferrets. some biological properties were also compared and differences were found in their ability to agglutinate erythrocytes from various species, in their ability to adsorb onto rat and fowl erythrocytes, and in their rates of elution from th ...1978104696
[neural secretion of histamine by the gastric mucosa and its effects on gastric motility]. 197890747
serologic examination of the westphal-type lipopolysaccharides of pasteurella multocida.the serologic specificities of the westphal-type lipopolysaccharides from 16 serotypes of pasteurella multocida were compared with those reported for the heat-stable typing antigens in the gel diffusion precipitin test. like the heat-stable typing antigen, the westphal-type lipopolysaccharide from each of the serotypes reacted only with its homologous antiserum in 14 of the 16 serotypes. the lipopolysaccharide from type strains representing serotypes 2 and 5 reacted with either of the correspond ...197882415
[intestinal rest. technique. indications. results (author's transl)]. 197896646
sexual behavior and hormone levels during the menstrual cycles of rhesus monkeys. 1978108191
total elbow replacement.this is a report of a total elbow low friction arthroplasty consisting of a vitallium humeral component and a high density polyethylene ulnar component equipped with a special snap-lock fit joint. the immediate results in 16 patients are most encouraging.19781277676
[perioperative changes in blood coagulation in aortofemoral bifurcation bypass]. 19781282736
pharmacology of hemostatics and anticoagulants in dental medicine. 1978275189
the evaluation of primary aldosteronism. 1978421943
spontaneous regression of a malignant primary bone tumour.a histologically confirmed malignant, primary bone tumour in the pelvis, presumably an osteosarcoma, underwent spontaneous regression. the large tumour was inoperable and gave rise to severe pain as well as difficulty in walking. after 2 years of progression, with increasing desition improved spontaneously, and at present the patient is alive, almost symptom-free, after 6 years follow-up.1978274896
[urinary lhrh: radioimmunological assay and physiological significance].a lhrh-like substance is detectable in the urine. it is extractable by glass powder, which suggests that it is a peptide, and it can be concentrated by anti-lhrh affinity chromatography, strongly suggesting that it is not a contaminant in the ria. it is composed of very little intact lhrh, and the great majority appears as multiple smaller fractions, although the possibility of "urinary lhrh" being a slightly larger peptide containing a sequence similar or identical to that of lhrh has not been ...1978352463
sonographic evaluation of mesenteric and omental masses in children.masses in the mesenteries and omentum are often difficult to diagnose by conventional radiographic techniques. gray scale sonography was a valuable adjunct to radiographic vector analysis in four children with such masses. masses that are clearly separable from the liver and spleen and do not distort identifiable extraperitoneal structures are probably intraperitoneal. in children most cystic intraperitoneal masses are related to the mesenteries, omentum, ovary, or bile ducts. an anterior fluid ...1979414577
chromosomes in malignant lymphomas (study on short-term lymph node cultures).in 15 cases, chromosome studies were performed in short-term lymph node cultures, using the banding technique. clonal aberrations were found in two cases of hodgkin's disease and in two of lymphosarcoma. in agreement with earlier observations, the cases of lymphosarcoma with abnormal karyotypes proved hyperdiploid. no chromosomal aberrations were found in three cases of reactive lymphoreticular hyperplasia.1979352853
an avirulent live pasteurella multocida vaccine for drinking water and aerosol administration against turkey cholera.a naturally avirulent isolant of pasteurella multocida (heddleston sero-type 3) was investigated as a seed strain for the development of a live vaccine against turkey pasteurellosis. laboratory trials showed that when given in aerosol form at a dosage of 5 x 10(8) c.f.u. per m(2), of barn floor, the vaccine produced satisfactory protection against both homologous and heterologous serotypes challenge administered by aerosol. likewise, turkeys vaccinated once, twice or three times, and challenged ...197918770466
synthetic antigens iii. antigen-binding cells to interpolymer of styrene and maleic acid psm and sheep red blood cells in mice immunized with psm.studies on the immune response in mice to a new synthetic antigen interpolymer of styrene and maleic acid (psm) are described. the immune response was measured by determination of antigen binding cells by means of rosette test with psm-coated srbc, an unexpected effect was observed--besides rosette-forming cells for psm, rosette-forming cells and agglutinating antibodies for sheep red cells were found. the results presented in this paper suggest that psm is acting both as an immunogen and a poly ...197994989
[resistence of head lice against gammexane (lindane) applies also to the nonalcoholic preparations]. 197985264
studies on the action of histamine release by persulphates. 197989996
evidence for reappearance of trypanosoma brucei variable antigen types in relapse populations.seven out of 11 bovines infected with different clones of trypanosoma brucei showed 2 peaks of antibody activity against the infecting clone within 7 weeks, as measured by immunofluorescence, radioimmunoassay, and neutralization of infectivity tests. using other clones from an unrelated stock, antibodies to these clones were not detectable, indicating that the antibodies produced were specific to the infecting organisms. these results suggest that there was a reappearance or increase in numbers ...197992560
membrane changes during growth of tetrahymena in the presence of ethanol.after a brief lag period for acclimation, tetrahymena pyriformis, strain nt-1, is capable of growing in culture medium containing high levels of ethanol. when grown in a medium having 1.6% ethanol, the membrane phospholipid composition was significantly different from that of control cells. the principal changes included a reduction in hexadecenoic acids (16 : 1 and 16 : 2) from 23% to 5% and an increase in linoleic acid (18 : 2) from 14% to 25% similar but less pronounced changes were observed ...1979105757
[deoxyribonucleic acids from pasteurella multocida and pasteurella haemolytica].pasteurella multocida and p. haemolytica strains contain between 1.5 and three per cent phosphorus, between nine and 14 per cent nitrogen, between two and four per cent dna, and between five and 18 per cent rna, the precise figures depending on culturing conditions. high-molecular dna may be isolated by means of bacteriolysis, using deoxycholate or dodecylsulphate and the usual steps of purification, with yield and purity differing by strains. dna with sufficient purity can be obtained from seph ...197993955
[histological and histochemical studies of the gastric mucosa of the mouse under normal conditions and following various treatments]. 197994241
transducing activity of bacteriophage spp1. 1979106856
[lactic acid bacteria and streptococci of the human stomach normally and in pathological processes].lactic acid bacteria were either absent or present in negligent quantities in the stomach of apparently healthy man. but in case of various pathological processes in the stomach and duodenum lactic acid bacteria accumulated (up to a million cells per 1 ml of gastric contents). under these conditions coccal forms sharply prevailed over the bacillary ones. in patients with chronic gastritis and peptic ulcer of the stomach the most frequent were streptococcus faecalis and its variants; in oncologic ...1979107685
transcription and translation in a pleiotropic streptomycin-resistant mutant of escherichia coli.the role of the ribosomal protein s12 (streptomycin protein) in ribosome function and in other metabolic processes in the cell has been investigated. a spontaneous streptomycin-resistant strain of escherichia coli (sm3) carrying a mutation in the rpsl gene is deficient in its ability to induce the synthesis of the enzyme bets-galactosidase. it was demonstrated that the reduced rate of enzyme synthesis results from deficiencies in both the transcription of the lactose operon and translation of th ...1979104958
isolation and characterization of an endogenous inhibitor of protein synthesis in escherichia coli k-12.a low-molecular-weight factor was isolated from cell extracts of escherichia coli k-12. the concentration of the factor in cells was dependent upon nutritional conditions, the concentration being higher in faster growing cells. treatment of cells with colicin k caused an increase in concentration of the factor. the factor inhibited protein synthesis in e. coli. this inhibition was reversible, apparently because of metabolism of the factor. the inhibition of synthesis of beta-galactosidase lasted ...1979104965
mutual antagonism of behavioral effects of trh and thiobarbiturate on an operant task in rhesus monkeys.similar excitatory or depressant response rate dependent effects on monkeys responding on a variable interval reinforcement schedule were observed following intravenous administration of either thyrotropin releasing hormone (trh) or thiobarbiturate. however, these agents were mutally antagonistic when given together even though the response rate altering effects of each agent were in the same direction. these findings establish an additional behavioral effect of exogenously administered trh in p ...1979108712
[bactericidal effect of disinfectants on various strains of mycobacterium tuberculosis]. 1979113848
double antibody specificity of lymphoid cells isolated from normal human intestinal mucosa.lymphoid cells were isolated from normal human mucosal specimens. a certain fraction of these cells exhibited double antibody specificities at the levels of both light kappa and lambda chains and heavy mu and gamma chains. the variable frequency with which these cells were detected appears to be a characteristic of this population. they represent a very low proportion of the total number of cells isolated.1979114243
bacterial fusion assayed by a prophage complementation test.in previous studies of bacterial protoplast fusion, only the frequencies of cell wall regeneration and of bacterial recombination were determined. in this work the frequency of the heterozygous fusion products is measured by prophage complementation. two multiply marked nonsuppressing strains of bacillus subtilis, each lysogenic for a different sus mutant of the phage phi 105, were induced by mitomycin c, protoplasted, fused, and, after dilution in hypertonic broth, incubated until plating with ...1979108245
presence of plasma cells binding autologous antibody during an immune response.spleen and other lymphoid tissues of rabbits immunized with human serum albumin (hsa) and human lactoferrin (lf) were examined for the presence of cells forming anti-idiotype antibodies. to detect these cells, igg, f(ab')2, or fab' of specific antibodies were isolated, fluorochrome-tagged with tetramethylrhodamine isothiocyanate, and used as an idiotypic marker to detect splenic plasma cells that are producing anti-idiotypic antibody. by this procedure, we were able to demonstrate anti-idiotypic ...197991659
continuous production of monoclonal mouse ige antibodies with known allergenic specificity by cell fusion. 197991948
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