Publications

[epidemics of yersinia enterocolitica infections].		1975	1179383
diverse effects of bursectomy on humoral immune responses in the chicken.	chickens bursectomized hormonally or surgically at various ages in embryonic to postembryonic lives were immunized with a mixture of antigens, and the antibodies produced titrated. immune responses to salmonella pullorum (sp), brucella abortus (ba). staphylococcus aureus (staph) and ovalbumin (oa) were more markedly suppressed by the bursal deprivation than those to heterogenous erythrocytes, viruses and such bacteria as pasteurella multocida (pm) and escherichia coli b. the immune response to b ...	1975	1187514
rheumatic fever in adult patients.	a study of rheumatic fever in adult patients (diagnosed according to the jones revised criteria; circulation 36: 664, 1965) was performed by examining 26 patients during the acute phase of the disease, and by re-examining 22 of them from 6 months to 64 months later (mean 33 months). polyarthritis and carditis were the most common major manifestations. 23 patients had polyarthritis and 3 monoarthritis. 18 patients had signs of acute cardiac involvement. carditis appeared to be rather benign: at t ...	1975	1190707
pasteurella multocida meningitis--case report.		1975	1192993
[yersiniosis enterocolitica serotype 9 in northern sweden].		1975	1195920
[participation of yersinia in infections in patients treated for acute abdominal diseases].		1975	1197093
[preventive properties of blood sera of rabbits immunized with 3 vaccines by separate, complex and combined application].		1975	1199562
letter: cross-sensitivity to cephalosporins.		1975	1199913
electrophoretic studies of the yersiniae.		1975	1200261
[the biological significance of zinc (author's transl)].	zinc takes part in the catalytic function of many metalloenzymes. in others it plays a role in conformational stability. in zinc deficient animals protein synthesis is disturbed. conversely zinc metabolism is influenced by protein deficiency. zinc takes part in drug metabolism, in mobilizing vitamin a from the liver, and in a system defending the organism against free radical damage. zinc distribution in the organism is influenced by steroid hormones and leucocytic endogenous mediators. of the i ...	1975	1200335
pasteurellosis in african grey parrots (psittacus erithacus l.).		1975	1200951
avian febrile response.	the febrile response of the pigeon (columba livia) was characterized for comparison with our present day understnading of mammalian fever. 2. when injected with live pasteurella multocida the birds became febrile and died. 3. varying doses of dead bacteria produced a complex dose-dependent febrile response. 4. antipyretics effectively attenuated the febrile response to dead bacteria. 5. the similarities of reptilian, avian and mammalian fever suggest a common origin and perhaps a similar adaptiv ...	1975	1204628
[current zoonoses in veterinary practice. 2. bacterial infections].		1975	1209594
[aerosol immunization of poultry against pasteurellosis].		1975	1209924
[study of dermanyssus gallinae as a carrier of pasteurella multocida].	microbiologic studies and biologic experiments revealed that pasteurella multocida persists in the body of dermanyssus gallinae mites after these engorge with blood from infected birds. depending on the temperature of the environment the carrier status was shown to last from 42 to 64 days. it is reported that the red mite acts as a vector and does not transmit pasteurellae directly. however, the parasite is potentially hazardous in maintaining and passing on the infection through other indirect ...	1975	1210004
[morphogenesis and some problems of the pathogenesis of experimental pasteurella infection in white mice].	the authors present materials on the study of the principal stages of morphogenesis of experimental pasteurellosis infection in albino mice in subcutaneous, intraperitoneal and intranasal infection. particular attention was paid to the interrelations in the organism between the cells realizing the protective functions and the causative agent. it was established that the highly-virulent p. multocida strain was capable of intracellular reproduciton in the cells of the macrophage type. it was demon ...	1975	1210901
skin manifestations in human yersiniosis.	in 1969-1973, acute yersiniosis was diagnosed in 30 cases of erythema nodosum (en), in 6 cases of en and simultaneous erythema multiforme (em), in one case of en and erythema figuratum, in one case of em, and in one case of drug eruption-like exanthema, respectively. during these years, 180 patients with en due to other causes were seen. the most marked difference in the clinical course between yersiniosis and other cases was the duration of the eruption. en nodules in yersinia en faded away in ...	1975	1211852
[appendicular form of intestinal yersiniosis].	the authors report twenty three cases of intestinal yerseniosis revealed among 575 patients operated upon for acute appendicitis. the diagnosis was supported bacteriologically and serologically. the disease proceeded with a predominant involvement of the appendicular process. various forms of acute appendicitis were observed. common appendicitis was noted in 6 cases, phlegmonous--in 15, gangrenous--in 2.	1975	1216398
[immunoreactivity of swine to vaccination against aujeszky's disease, salmonellosis and pasteurellosis].		1975	1216528
[combined vaccination of sheep against pasteurellosis and anaerobic infections].		1975	1216597
[serological indicators of microagglutination and lysis in rabbits immunized simultaneously against leptospirosis, pasteurellosis ans brucellosis].		1975	1220472
erythema nodosum from yersinia enterocolitica.		1975	1220819
a comparison of commercial mycoplasma gallisepticum antigens in the rapid serum agglutination test.	twenty-three chickens, aged 9 weeks, were housed in contact with a similar group of chickens which were infected with m. gallisepticum. the onset and development of the serum agglutinin responses which were detected by 3 commercial antigens using rapid serum agglutination tests up to 20 weeks of age, differed greatly both between the infected and in-contact groups and, within the latter group, between the antigens. few reactions, which were weak and transient, were detected in 2 similar groups o ...	1975	1222006
[serologic typing of strains of pasteurella haemolytica isolated from sheep].	typed were a total of 85 strains of pasteurella haemolytica isolated from lambs, weaned lambs, and adult sheep in cases of septicemia and broncho-pneumonia applying the hemagglutination-inhibition reaction and making use of capsule antigens and anti-capsule hyperimmune sera. it was found that 74 strains belong to biotype a, five belong to biotype t, and six remained untyped. most wide spread in this country proved serotype a2--35 strains, followed by serotype a6--14 strains.	1975	1226701
the ability of blood plasma from drinking water vaccinated turkeys to protect against a lethal challenge of pasteurella multocida.	turkeys were vaccinated against fowl cholera with the clemson university avirulent pasteurella multocida vaccine strain (c.u. strain), using the drinking water route. plasma was harvested from these turkeys, which later withstood challenge with a highly virulent p-1059 strain of p. multocida. baby chicks were injected between the thigh and abdominal cavity with the immune plasma and simultaneously, into the breast muscle, with the same highly virulent strain referred to in the foregoing. the res ...	1975	1228730
lesions of central nervous system in a calf due to a pasteurella organism.		1975	1238868
[the incidence of pasteurella multocida in patients with lung diseases].		1976	1244595
gastritis and gastric blood flow in hyperdynamic septic pigs.	the present study was designed to determine the gastric hemodynamics in a septic model that causes both a hyperdynamic state and acute erosive gastritis. sepsis was established in twelve pigs by the intramuscular shank injection of pastuerella multocida (42 x 10(8) colonies) in triptose phosphate broth; four pigs received sterile broth injections (shams) and eight received sterile saline injections (controls). after 18 hours, cardiac output was measured by both the cardiogreen dilution technic a ...	1976	1247158
subversion of host defense mechanisms by murine tumors. i. a circulating factor that suppresses macrophage-mediated resistance to infection.	the subcutaneous injection of cells of any one of five unselected murine tumors resulted very rapidly in the liberation into the circulation of a small molecular weight factor that severely impaired the capacity of the host to resist experimental infection with listeria monocytogenes and yersinia enterocolitica. it was found that the factor appeared in blood within 8 h of injecting tumor cells subcutaneously. that it possessed potent physiological activity was evidenced by the demonstration that ...	1976	1249520
[diseases caused by yersinia enterocolitica in childhood].		1976	1253224
[yersinia enterocolitica and yersinia pseudotuberculosis in the pathogenesis of abdominal pain in children].		1976	1256919
[erythema nodosum secondary to infection caused by yersinia enterolitica bacilli (1st case reported in poland)].		1976	1257509
isolation of a protective, non-toxic capsular antigen from pasteurella multocida, types b and e.	separation of the capsular antigen and endotoxin from saline extracts of pasteurella multocida type b was achieved by fractional precipitation from aqueous solution by addition of polar organic solvents. biological tests for the presence of endotoxin showed that it was absent from capsular antigen preparations so obtained. properties of the capsular antigen suggested that it was a high molecular weight acidic polysaccharide. the solvent fractionation method was found to be equally applicable to ...	1976	1257631
[possible relationship between bacterial surface structures, immune-adherence, chemotaxis and phagocytosis (author's transl)].	in the present study we attempted to determine the relationship between bacterial surface structures, immune adherence, chemotaxis and phagocytosis. as shown in table 1 encapsulated bacteria (klebsiella ozanae, k. pneumoniae, pasteurella multocida, streptococcus pneumoniae), mycoplasma pneumoniae and m. fermentans had a much lower immune adherence-activity than non-encapsulated bacteria (bacillus cereus, brucella abortus, erysipelothrix insidiosa, escherichia coli, listeria monocytogenes, pseudo ...	1976	1258564
[kinetics of bacterial infections in hens].		1976	1259695
the masked rat. an x-ray induced mutant with chronic blepharitis, alopecia, and pasteurellosis.	an autosomal recessive mutation had been previously x-ray-induced in the rat and named the masked rat (genotype mk/mk). this study describes the mutant's appearance, histology, and microflora. the rat's eyelids were swollen, often to the point of closure, and its face was partially covered by a brownish crust, giving the mutant a mask-like appearance. the chronic blepharitis was also accompanied by alopecia that appeared as bare patches across the mutant's back. pasteurella pneumotropica was fou ...	1976	1262697
homogeneity of pasteurella avicida bacterin.	a simple rapid procedure is described for determining whether an emulsified bacterin is homogenous by measuring the uv absorbances of chloroform-washed centrifugates. these absorbances appear to depend on nucleic acid content.	1976	1263098
experimentally produced calf pneumonia.	experimental pneumonia was produced in calves by the endobronchial inoculation of pneumonic lung homogenates. irradiated homogenates produced minimal pneumonia. ampicillin treatment of the homogenates and the experimental calves reduced the extent of pneumonia. treatment with tylosin tartrate prevented experimental pneumonia. these results suggest that the total pneumonia was due to organisms susceptible to tylosin tartrate and that the residual pneumonia remaining after ampicillin treatment was ...	1976	1265354
[role of the cellular components of p. multocida in the development in poultry of immunity to pasteurelloses].		1976	1266024
pasteurella aerogenes isolations from swine.		1976	1266448
studies on crohn's disease. 1. the relationship between yersinia enterocolitica infection and terminal ileitis.	patients with terminal ileitis or regional enterocolitis have been examined for signs of infection due to yersinia enterocolitica serotype 3. the patients were grouped according to the length of preoperative history. among 18 patients with preoperative symptoms of one week or less there were nine with positive signs of yersinia enterocolitica infection. none of these patients developed the chronic form of crohn's disease while two of the primarily yersinia negative patients progressed to the chr ...	1976	1266547
gingival flora of the dog with special reference to bacteria associated with bites.	gingival scrapings from dogs were examined to determine their aerobic bacterial flora. of particular interest was the frequent recovery of three unclassified groups of aerobic gram-negative bacteria, iij, ef-4, and m-5, previously associated with human dog-bite infections. although no set pattern was found between the variability and consistency of gingival microbiota as related to age, sex, or breed of dog, a certain characteristic flora can be predicted in the healthy canine gingiva. members o ...	1976	1270595
immune responses to pasteurella multocida in the mouse.		1976	1271385
proceedings: yersinia enteritis and enterocolitis.		1976	1278745
the glycoprotease of pasteurella haemolytica a1 eliminates binding of myeloid cells to p-selectin but not to e-selectin.	hl-60 cells and neutrophils treated with the glycoprotease from pasteurella haemolytica a1, an enzyme which is specific for o-sialoglycoproteins, were found to be incapable of binding p-selectin but still bound e-selectin. comparative analysis of [35-s] cysteine labeled proteins from hl-60 cells by 2-dimensional electrophoresis indicated that two major proteins with m(r) 100 and 115 kd were significantly removed from cells which had been treated.	1992	1280121
a characterization of monoclonal antibodies prepared against pasteurella haemolytica serotype 1 surface antigens.	the production and characterization of monoclonal antibodies against pasteurella haemolytica serotype 1 is described. ten monoclonal antibodies were produced and divided, on the basis of their properties, into six different groups. one produced bacteria agglutination only of p. haemolytica serotype 1. three antibodies bound with p. haemolytica serotypes 1, 5-8 and 12 and the antigen was identified in immunoblots as lipopolysaccharide. two antibodies bound p. haemolytica serotypes 1, 2, 5-8 and 1 ...	1992	1280877
lipopolysaccharide heterogeneity in pasteurella haemolytica isolates from cattle and sheep.	lipopolysaccharide (lps) from 40 isolates of pasteurella haemolytica, comprising 23 serotype a1, seven serotype a2, one serotype t4, one serotype t10 and eight untypable isolates, obtained from diseased and healthy cattle or sheep, was characterized by sds-page and western blotting. ten different sds-page lps profiles, five smooth and five rough, were identified among the biotype a and untypable isolates and designated lps types 1-10. lps types 1 and 2 were smooth, had similar o-antigen banding- ...	1992	1282533
leishmania major: bacterial contamination of cutaneous lesions in experimental animals.	no bacterial contamination has been demonstrated in cutaneous leishmaniasis (cl) nodule and in lesions caused by leishmania major in balb/c mice up to 20 days after infection. however, although many phagocytic cells (polymorphonuclear leukocytes and macrophages) were present in the cl lesion, 80% of the lesions showed bacterial contamination that developed within the first 70 days of infection. topical treatment of the lesion with an ointment containing 15% paromomycin and 12% methylbenzethonium ...	1992	1286954
pasteurella multocida infection in singapore.	a case of pasteurella multocida infection in singapore is presented. the patient was a 21-year-old chinese male who developed fever and cellulitis with abscess formation of his right index finger after it was bitten by a stray cat. the organism was isolated in pure culture and identified as pasteurella multocida subspecies septica. the patient responded to antibiotic therapy and had an uneventful recovery.	1992	1295147
controlling tick infestations and diseases in sheep by pour-on formulations of synthetic pyrethroids. a field study.	the use of synthetic pyrethroids in pour-on formulations reduced tick infestations and the incidence of tick-associated diseases in lambs more than dipping in organophosphate acaricides. though the use of pyrethroids did not prevent the lambs from being infected with tick-borne fever (tbf), the incidence of lambs with lameness (tick pyaemia) or lambs suddenly found dead (pasteurella haemolytica septicaemia), which often are seen in association with tbf, was reduced. the use of pyrethroids for th ...	1992	1295204
pasteurella haemolytica diagnosis questioned.		1992	1298273
[severe pasteurella multocida cellulitis. 2 cases].		1992	1301701
an outbreak of haemorrhagic septicaemia (septicaemic pasteurellosis) in cattle in zimbabwe.	an outbreak of haemorrhagic septicaemia caused by pasteurella multocida in beef cattle in zimbabwe grazing effluent-irrigated pastures, is described. the outbreak occurred during the wet summer months and predisposing stress factors included excessive rainfall and unusual cold weather during the preceding month. history, clinical features and post-mortem findings were consistent with reports of the disease from other countries, except that meningitis was also a constant feature. morbidity approa ...	1992	1305340
serological survey for bovine bacterial and viral pathogens in captive arabian oryx (oryx leucoryx pallas, 1776).	tests for antibodies to bovine bacterial and viral pathogens were conducted on 239 sera from 128 arabian oryx (oryx leucoryx) from seven locations (taif, riyadh and mahazat as said, saudi arabia; san diego, united states of america [usa]; shaumari, jordan; qatar; and bahrain). no antibodies to pasteurella multocida type e or epizootic haemorrhagic disease 1 virus were found. antibodies to brucella abortus, p. multocida type b, p. multocida type d, lumpy skin disease virus and akabane virus were ...	1992	1305861
pasteurella haemolytica infection in a goeldie's monkey.	an adult male callimico goeldii died spontaneously. at necropsy, small whitish foci were found randomly distributed on the liver surface. histologically, the foci were composed of mixed inflammatory cells with predominant polymorphonuclear cell infiltration and central areas of necrosis. microbiological cultures revealed a gram-negative coccoid-bacilli with bipolar staining. biochemical analysis revealed that the microorganism was pasteurella haemolytica.	1992	1307760
synthesis and structure-activity relationships of 7-diazabicycloalkylquinolones, including danofloxacin, a new quinolone antibacterial agent for veterinary medicine.	a series of novel 6-fluoro-7-diazabicycloalkylquinolonecarboxylic acids substituted with various c8 (h, f, cl, n) and n1 (ethyl, cyclopropyl, vinyl, 2-fluoroethyl, 4-fluorophenyl, 2,4-difluorophenyl) substituents, as well as, 9-fluoro-10-diazabicycloalkylpyridobenzoxazinecarboxylic acids, were prepared and evaluated for antibacterial activity against a range of important veterinary pathogenic bacteria. the diazabicycloalkyl side chains investigated at the 7-position (benzoxazine 10-position) inc ...	1992	1311762
release of tumor necrosis factor-alpha from bovine alveolar macrophages stimulated with bovine respiratory viruses and bacterial endotoxins.	the release of tumor necrosis factor-alpha (tnf-alpha) from cultured bovine alveolar macrophages (bam) was evaluated following stimulation of bam with bovine herpesvirus-1 (bhv-1), parainfluenza-3 (pi-3) virus, bovine respiratory syncytial virus (brsv), escherichia coli 0111:b4 endotoxin, pasteurella haemolytica type 1 endotoxin, pasteurella multocida endotoxin, and virus/endotoxin combinations. a cytotoxic assay system using georgia bovine kidney cells as targets was used to measure tnf-alpha a ...	1992	1312264
colonization of rabbits by pasteurella multocida: serum igg responses following intranasal challenge with serologically distinct isolates.	enzyme-linked immunosorbent assays (elisas) and immunoblots were used to measure serum igg responses in rabbits which were intranasally challenged with pasteurella multocida. the responses to two serologically distinct isolates (isolate 1, serotype 3:a and isolate 10, serotype 1:d) were compared and then correlated with the ability of the isolates to colonize the nasal passages. five rabbits were challenged with each isolate (10(5) cfu); nasal washings and sera were collected weekly for 8 weeks. ...	1992	1316502
effects of pasteurella haemolytica a1 leukotoxin on bovine neutrophils: degranulation and generation of oxygen-derived free radicals.	to further define the role of pasteurella haemolytica a1 leukotoxin in the pathogenesis of bovine pneumonic pasteurellosis, its in vitro effects on bovine neutrophils were investigated. leukotoxin-containing culture supernatant, from p. haemolytica, stimulated a neutrophil respiratory burst as measured by the generation of oxygen-derived free radicals o2- and h2o2. this effect was immediate because preincubation of neutrophils with the culture supernatant for 5 min or longer substantially suppre ...	1992	1321532
pasteurella haemolytica leukotoxin enhances production of leukotriene b4 and 5-hydroxyeicosatetraenoic acid by bovine polymorphonuclear leukocytes.	the influence of the leukotoxin of pasteurella haemolytica on the generation of arachidonic acid metabolites by bovine polymorphonuclear leukocytes (pmns) was investigated. pmns released 5-, 12-, and 15-hydroxyeicosatetraenoic acids (5-, 12-, and 15-hete) and leukotriene b4 (ltb4) upon stimulation with arachidonic acid. the leukotoxin preparations dose dependently enhanced the release of the 5-lipoxygenase products 5-hete and ltb4 in arachidonic acid-stimulated pmns, whereas the release of 12- a ...	1992	1322370
using ribosomal rna gene restriction patterns in distinguishing isolates of pasteurella haemolytica from bighorn sheep (ovis canadensis).	pasteurella haemolytica isolates (n = 31) from two isolated captive herds of rocky mountain bighorn sheep (ovis canadensis canadensis) were characterized and compared phenotypically (biotype, serotype, hemolytic activity) and by a genomic fingerprinting method known as ribotyping. seven to nine distinct phenotypes were observed. depending on the method used for serotyping, one to three phenotypes were common to both herds. eighteen isolates, recovered from both herds, were non-hemolytic, biotype ...	1992	1324994
pasteurella multocida chorioamnionitis from vaginal transmission.	a 21 year old primigravida with a twin pregnancy developed pasteurella multocida chorioamnionitis. infection occurred at 27 weeks gestational age after prolonged rupture of membranes. the twin in the separate sac presenting proximal to the cervix suffered infection and died shortly after birth whereas the other twin was not infected. the bacterium is believed to have caused ascending infection from asymptomatic colonization of the vaginal tract.	1992	1326216
secondary bacterial infections following an outbreak of equine influenza.		1992	1333669
characterization of plasmids with antimicrobial resistant genes in pasteurella haemolytica a1.	two r plasmids, pyfc1 and pyfc2, from pasteurella haemolytica a1 encoding sulfonamide, streptomycin (pyfc1), and ampicillin (pyfc2) resistances have been characterized by restriction endonuclease digestions, subcloning or dna sequencing. pyfc1 consists of 4225 bp and is 51.9% in at content. physical mapping indicated a highly conserved region of restriction sites among pyfc1, rsf1010, pgs05, pfm739, phd148 and pgs03b. pyfc1 encoded a dihydropteroate synthase (29.8 kda), and streptomycin kinase ( ...	1992	1333838
pasteurella multocida toxin selectively facilitates phosphatidylinositol 4,5-bisphosphate hydrolysis by bombesin, vasopressin, and endothelin. requirement for a functional g protein.	treatment of swiss 3t3 cells with a subsaturating concentration of recombinant pasteurella multocida toxin (rpmt) markedly potentiated the production of inositol phosphates induced by bombesin, vasopressin, and endothelin but not by platelet-derived growth factor (pdgf) (aa and bb homodimers). similarly, the neuropeptides but not pdgf caused a shift in the dose-dependent increase in inositol phosphates induced by rpmt. the rate of accumulation of inositol phosphates induced by bombesin was incre ...	1992	1334089
serological titers to bovine herpesvirus 1, bovine viral diarrhea virus, parainfluenza 3 virus, bovine respiratory syncytial virus and pasteurella haemolytica in feedlot calves with respiratory disease: associations with bacteriological and pulmonary cytological variables.	acute and convalescent serum samples were taken from 59 calves with signs of respiratory disease (cases) and 60 clinically normal animals (controls) during their first month in the feedlot. sera were analyzed for antibodies to bovine parainfluenza 3 (pi3) virus by hemagglutination inhibition, to bovine viral diarrhea (bvd) virus, bovine respiratory syncytial (brs) virus and bovine herpesvirus 1 (bhv1) by virus neutralization, and to pasteurella haemolytica by indirect agglutination (phia) and cy ...	1992	1335831
in vitro susceptibility of avian escherichia coli and pasteurella multocida to danofloxacin and five other antimicrobials.	the in vitro susceptibility of escherichia coli and pasteurella multocida isolated from poultry was determined to danofloxacin, a novel fluoroquinolone, and five other commonly used antimicrobials. a total of 1737 e. coli field isolates and 107 p. multocida isolates were tested by veterinary diagnostic laboratories in europe, japan, south africa, and north america during the period 1989-91. the antimicrobial susceptibility of these isolates was determined using the sensititre broth microdilution ...	1992	1336664
use of restriction endonuclease analysis and ribotyping to study epidemiology of pasteurella multocida in closed swine herds.	one hundred and sixty-four clinical isolates of pasteurella multocida recovered from two swine herds in minnesota were characterized by restriction endonuclease analysis (rea) and rrna gene restriction fragment length patterns. bacterial dna was digested with hpaii and electrophoresed in 0.55% agarose. restriction fragments were transferred by southern blot to nylon membranes and then hybridized with digoxigenin-dutp-labeled escherichia coli rrna. four different rea patterns were observed among ...	1992	1347761
cleavage of the cell-surface o-sialoglycoproteins cd34, cd43, cd44, and cd45 by a novel glycoprotease from pasteurella haemolytica.	the study of structural/functional characteristics of the cell-surface glycoproteins of leukocytes has led to a better understanding of the differentiation and maturation of hematopoietic cells. we have assessed the ability of a unique metalloprotease that is secreted by the bovine fibrinous pneumonia pathogen pasteurella haemolytica, to cleave cell-surface glycoproteins expressed on human leukocytes. biochemical analysis shows that the o-glycosylated cell surface ag cd34, cd43 (leukosialin), cd ...	1992	1371528
characterization of a neutralizing monoclonal antibody to pasteurella haemolytica leukotoxin.	six hybridoma clones producing monoclonal antibodies (mabs) reactive with pasteurella haemolytica a1 leukotoxin were derived from mice immunized with leukotoxin excised from sodium dodecyl sulfate-polyacrylamide gels. of the six mabs, only one, ltx-2, neutralized leukotoxin in a bl-3 cell cytotoxicity assay. mab ltx-2 blocked association of a1 leukotoxin to bl-3 cells, as measured by flow cytometric analysis. the epitope recognized by ltx-2 was localized to the carboxyl half of the native protei ...	1992	1373398
antigenic analysis of iron-regulated proteins in pasteurella haemolytica a and t biotypes by immunoblotting reveals biotype-specific epitopes.	the antigenic relationships of the iron-regulated proteins (irps) in pasteurella haemolytica a and t biotype strains were examined by sds-page and immunoblotting. p. haemolytica cells of the a biotype, grown under conditions of iron-limitation, expressed two irps, of 35 and 70 kda. all t biotype strains expressed irps with slightly different molecular masses of 37 and 78 kda. immunoblotting of all 16 p. haemolytica serotypes was carried out using a panel of polyclonal and monoclonal antibodies r ...	1992	1373434
differential sensitivity of cd34 epitopes to cleavage by pasteurella haemolytica glycoprotease: implications for purification of cd34-positive progenitor cells.	our previous studies have shown that a unique glycoprotease from pasteurella haemolytica specifically cleaves only proteins containing sialylated o-linked glycans. the hematopoietic progenitor cell antigen, cd34, which is heavily glycosylated with both n- and o-linked glycans, is readily cleaved by this protease. in this study, we demonstrate that the epitopes detected by five of the seven cd34 monoclonal antibodies are removed by the glycoprotease. the differential sensitivity of the cd34 epito ...	1992	1375160
comparison of dna fingerprints and somatic serotypes of serogroup b and e pasteurella multocida isolates.	the dna fingerprint profiles and somatic serotypes of 71 pasteurella multocida capsule serogroup b isolates, 13 capsule serogroup e isolates, and 16 somatic reference serotype strains were compared. each of the 16 reference somatic serotypes had a unique dna fingerprint profile with the hhai restriction endonuclease. fifty-four serogroup b isolates (isolated from classical cases of hemorrhagic septicemia) reacted with somatic serotype 2 or 5 antiserum and had dna fingerprint profiles which resem ...	1992	1378060
comparison of antibody responses in cattle to outer membrane proteins from pasteurella haemolytica serotype 1 and from eight untypeable strains.	membrane associated proteins from 8 untypeable pasteurella haemolytica strains were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and compared with those of p haemolytica serotypes 1 and 2. cattle antisera obtained from p haemolytica serotype 1 vaccine trials were used in immunoblotting assays to compare the membrane proteins from the 8 untypeable strains with those from p haemolytica serotypes 1 and 2. densitometry was used to identify bands, and using linear regression ...	1992	1378250
retention of progenitor cell function in cd34+ cells purified using a novel o-sialoglycoprotease.	we previously showed that the sialoglycoprotein, cd34, which is expressed on primitive human hematopoietic progenitor cells, is cleaved by a unique glycoprotease from pasteurella haemolytica (p.h. glycoprotease). this proteolytic enzyme specifically cleaves glycoproteins rich in o-sialoglycans. glycoproteins containing only n-linked glycans are not cleaved. cleavage of the cd34 antigen results in the loss of epitopes detected by five of seven cd34-designated antibodies. in this study, we investi ...	1992	1381456
identification and analysis of the gap region in the 23s ribosomal rna from actinobacillus actinomycetemcomitans.	actinobacillus actinomycetemcomitans is a gram-negative coccobacillus which can cause certain severe extra-oral infections as well as forms of human periodontal disease such as localized juvenile periodontitis. in contrast to many prokaryotic and eukaryotic species which exhibit an intact 23s ribosomal rna (rrna) molecule, examination of six a. actinomycetemcomitans strains--including three serogroup representative strains and two strains from non-human primates--revealed that this micro-organis ...	1992	1381732
experimental atrophic rhinitis in 2 and 4 month old pigs infected sequentially with bordetella bronchiseptica and toxigenic type d pasteurella multocida.	experimental infections with bordetella bronchiseptica and/or toxigenic type d pasteurella multocida were studied in 2- and 4-month-old primary specific-pathogen-free pigs. none of the 2-month-old pigs inoculated with b. bronchiseptica or p. multocida alone developed turbinate atrophy. all the pigs inoculated with b. bronchiseptica (10(7) cfu/head) and p. multocida (10(9) cfu/head for 5 consecutive days) together, however, developed clinical and post-mortem signs of atrophic rhinitis (ar) simila ...	1992	1385667
toxigenic type a pasteurella multocida as a causative agent of nasal turbinate atrophy in swine.	although no clinical signs of atrophic rhinitis (ar) were recognized in 2- and 5-week-old pigs, approximately 60% of 2- to 6-month-old pigs showed clinical signs of ar in an affected pig farm. none of the pigs had normal turbinate at slaughter. bordetella bronchiseptica was not isolated from any of the pigs before onset and incipient stage of the outbreak (2-week to 2-month-old). pasteurella multocida of capsular type d was not isolated from any of those pigs. however, toxigenic p. multocida of ...	1992	1386531
[a trial designed to obtain a specific pathogen free syrian hamster colony by administration of chemicals].	conventional syrian hamsters, contaminated with giardia spp., spironucleus muris, trichomonas spp., pasteurella pneumotropica and pseudomonas aeruginosa were treated with chemicals in order to obtain specific pathogen free animals. hamsters kept in the laminar flow rack were treated orally with metronidazole several times to obtain a flagellate-free colony. after all flagellates had been eradicated, one pair of animals were kept in an isolator and mating was allowed to occur. when their offsprin ...	1992	1387090
correction of orthography of epithets in pasteurella and some problems with recommendations on latinization.		1992	1390115
cloning and molecular analysis of the poly(3-hydroxyalkanoic acid) gene locus of pseudomonas aeruginosa pao1.	from genomic libraries, the polyhydroxyalkanoate gene locus of pseudomonas aeruginosa pao1 was cloned and characterised at the molecular level. two genes coding for polyhydroxyalkanoate synthases, phac1pa and phac2pa, a polyhydroxyalkanoate depolymerase gene, phadpa, and four adjacent open reading frames (orf1, orf2, orf3 and orf4) were identified from the nucleotide sequence. two transcriptional start sites, which were preceded by sequences resembling the escherichia coli consensus sequences fo ...	1992	1396693
[clinicobacteriological study of pasteurella multocida as a zoonosis (1). condition of dog and cat carriers of pasteurella, and the influence for human carrier rate by kiss with the pets].	pasteurella multocida is a gram-negative short rod-shaped bacteria, which is a part of the indigenous flora of the oral cavity of many animals other than man. the number of reports on cases of infections with this bacterium due to animal bites and/or scratches, bacterial infections of the respiratory tract, sepsis due to this organism and death caused by the bacteria have been increasing in recent years. we investigated p. multocida in the hair and oral cavity of 3 dogs and 29 cats according to ...	1992	1402084
[the first report of human chronic sinusitis by pasteurella multocida subsp. multocida in japan].	a 53-year-old male visited our hospital due to nasal obstruction persisting for 6 months and constant rhinorrhea. pasteurella multocida subsp. multocida was isolated from his nasal discharge and lavage fluid of the maxillary sinus, and also from the oral cavity of the dog he kept. the bacterial strains isolated from the patient and dog were identical in terms of biochemical properties, and drug sensitivity. although serotype was different, the strain from the patient showed (a:6) and that from h ...	1992	1402086
pasteurella multocida infection of a total hip arthroplasty. a case report.	the authors report a case history of a diabetic woman requiring revision hip arthroplasty of a charnley total hip prosthesis that was infected with pasteurella multocida. the infection of the loose prosthesis followed a cat bite to the same leg. advice is given on the management of patients with infection following animal inoculations, and the subject of increased risk with a loose prosthesis is discussed.	1992	1402948
cat-scratch salpingitis.		1992	1406855
light microscopic and ultrastructural pathology of seminiferous tubules of rats given multiple doses of pasteurella multocida group d protein toxin.	male holtzman rats were given subcutaneous doses of a purified pasteurella multocida group d heat-labile toxin on alternate days for up to 22 days. rats were necropsied at 18 days or 36 days (14 days after last dose of toxin) or when moribund, and testicles were taken for histologic and ultrastructural examination. other selected tissues, including liver and spleen, were taken for histologic examination. histologically, testicular and splenic lesions occurred more consistently and at much smalle ...	1992	1411123
severe pasteurella multocida infections in pregnant women.	we report 2 cases of severe infections due to pasteurella multocida, both occurring during pregnancy in previously healthy women. both women had contact with animals (dog and cat) but neither of them had been bitten. apart from a slight decrease in igg levels, no immunological defects could be detected. both women had received oral phenoxymethylpenicillin in the early phase of the disease, but still fell ill with severe infections. one woman had meningitis while the other suffered from celluliti ...	1992	1411311
systemic pasteurellosis.		1992	1413428
co-migrating and shared antigens of selected pasteurella haemolytica untypable strains.	bacterial cell envelope preparations from eight untypable strains of pasteurella haemolytica were compared by sodium dodecyl sulphate-polyacrylamide gel electrophoresis and immunoblotting with rabbit antisera prepared against the eight untypable strains (one untypable strain per rabbit) and with cattle antisera prepared against p. haemolytica serotypes 1, 2, 5, 6, 9 and against one heterologous untypable strain. numerous comigrating and shared antigens were recognized by the eight rabbit antiser ...	1992	1413477
an atypical strain of pasteurella gallinarum: pathogenic, phenotypic, and genotypic characteristics.	the pathogenicity of a strain of pasteurella gallinarum isolated in fresno county, calif., was compared with the american type culture collection (atcc) strain. broiler chickens were inoculated intranasally with 10(7) colony-forming units (cfu) and intramuscularly with 10(5) cfu of each strain. the only notable lesions were in chickens inoculated intramuscularly with 10(5) cfu of the fresno strain, which developed severe myositis at the inoculation site, pericarditis, perihepatitis, airsacculiti ...	1992	1417600
severe mortality in broiler chickens associated with mycoplasma synoviae and pasteurella gallinarum.	severe economic loss due to high mortality and condemnation rates occurred on two commercial broiler facilities. chickens had moderate-to-severe airsacculitis, pericarditis, perihepatitis, tracheitis, and synovitis. pasteurella gallinarum was isolated from 16 of 18 pericardia, four of 14 livers, 11 of 16 air sacs, six of seven joints and one of 28 tracheas in pure culture. in addition, mycoplasma synoviae was isolated from trachea and air sac. lesions were suggestive of an escherichia coli septi ...	1992	1417618
the synthesis and function of the escherichia coli hemolysin and related rtx exotoxins.	the rtx group of exotoxins represents a branch of a family of exoproteins produced by gram-negative bacteria which share the properties of being secreted by a leader-independent pathway and a tandemly-repeated nine-amino-acid sequence that is responsible for calcium binding. the escherichia coli hemolysin (hlya) is the prototype for the rtx exotoxin family which includes the leukotoxins of pasteurella haemolytica and actinobacillus actinomycetemcomitans and hemolysins from four gram-negative gen ...	1992	1419112
changes in the bacterial flora of the upper and lower respiratory tracts and bronchoalveolar lavage differential cell counts in feedlot calves treated for respiratory diseases.	serial nasopharyngeal swab and bronchoalveolar lavage cultures were used to estimate changes in the bacterial flora of the respiratory tracts of calves during the first month after arrival in the feedlot. bronchoalveolar lavage (bal) differential cell counts served to evaluate pulmonary inflammatory changes during this period. two groups of calves were studied, one consisting of clinically normal controls (n = 60), the other, of cases (n = 59) which received treatment for respiratory disease (pe ...	1992	1423052
effects of pasteurella haemolytica leukotoxic culture supernatant on bovine neutrophil aggregation.	pasteurella haemolytica a1 leukotoxic culture supernatant was evaluated for its ability to cause aggregation of bovine peripheral neutrophils. neutrophils were isolated by a hypotonic lysis method and incubated with zymosan-activated plasma (zap), leukotoxic culture supernatant, antileukotoxin serum, calcium and magnesium-free media, p-bromophenacyl bromide and protein kinase c inhibitors. aggregation was evaluated by changes in infrared light transmittance. leukotoxic culture supernatant caused ...	1992	1423054
enhanced adherence of pasteurella multocida to porcine tracheal rings preinfected with bordetella bronchiseptica.	adherence of 25 isolates of pasteurella multocida to porcine tracheal rings was evaluated. results indicated that adherence was not related to the isolate's origin, capsular or somatic types, dermonecrotoxin production or hemagglutination activity. the effect of a preinfection with bordetella bronchiseptica on the colonization by p. multocida was then studied. on rings infected with p. multocida alone, bacteria initially adhered to the epithelium, but within a few hours, the level of colonizatio ...	1992	1423064
activation of bovine neutrophils by pasteurella haemolytica leukotoxin is calcium dependent.	in this study, we used the fluorescent probe fluo-3 to show that an increase in cytosolic free calcium, [ca2+]i, occurred when suspensions of bovine neutrophils were incubated with sublethal concentrations of p. haemolytica leukotoxin. this increase in [ca2+]i was dependent on the concentration of leukotoxin present in the medium and, at a given concentration of leukotoxin, dependent on the external calcium concentration. the calcium channel blocker verapamil and the beta-adrenergic antagonist p ...	1992	1431567
interaction between ascaris suum and pasteurella multocida in the lungs of mice.	in an experiment including 8 groups of 15 mice, the effect of migrating ascaris suum larvae in the lungs on the establishment and pathogenicity of aerosol exposure to pasteurella multocida was investigated. following aerosol exposure to p. multocida, mice with migrating a. suum in their lungs developed more severe pneumonia and septicaemia than did parasite-free mice. the parasite-induced effect on bacterial pathogenicity was more marked for a non-toxin-producing p. multocida as compared with a ...	1992	1438140
[pulmonary pasteurellosis in a young patient with multiple trauma].	a case is reported of an 18-year-old male patient who had a road traffic accident, with head and chest injuries. the patient was admitted to the surgical intensive care unit 24 h later because of an alteration of his level of consciousness. he required artificial ventilation. five days later, he developed right-sided lower lobe pneumonia, treated with positive end-expiratory pressure. a gram negative organism was found on bronchial brushing, but not in haemocultures. it was identified as pasteur ...	1992	1443800
effects of sub-mics of antibiotics on cell surface characteristics and virulence of pasteurella multocida.	the effects of sub-mics of certain antibiotics, namely, penicillin g, tetracycline, and trimethoprim-sulfamethoxazole, on the cell surface characteristics and the virulences of two toxigenic isolates of pasteurella multocida representing capsular types a and d were evaluated. expression of proteins, in particular, outer membrane proteins and iron-regulated proteins, was not affected by exposure of bacterial cells to low concentrations of antibiotics. however, exposition of surface antigens was m ...	1992	1444290
phenotypic, antigenic, and molecular characterization of pasteurella piscicida strains isolated from fish.	we compared pasteurella piscicida strains isolated from different fish species in several european countries with strains isolated in japan and the united states. the taxonomic analysis revealed that, regardless of the geographic origin and source of isolation, all the strains exhibited the same biochemical and physiological characteristics. serological assays with different rabbit antisera demonstrated a high level of antigenic similarity among strains, with cross-agglutination titers of 20,480 ...	1992	1444366