Publications

TitleAbstractYear
Filter
PMID(sorted ascending)
Filter
pasteurella multocida empyema. 199617429265
ultrastructural characteristics of the external surfaces of pasteurella pneumotropica from mice and pasteurella multocida from rabbits.the surface structures of the cells of pasteurella pneumotropica from mice and pasteurella multocida from rabbits were examined by transmission electron microscopy after ruthenium red staining and polycationic ferritin labelling. p. pneumotropica strains atcc 35149 and k 79114 had slight extracellular fibrous materials associated with cell walls with ruthenium red staining. ferritin labelling method revealed thick strands or sparsely ferritin-labelled materials on the cell surface of the strains ...200717430628
the tad locus: postcards from the widespread colonization island.the tad (tight adherence) macromolecular transport system, which is present in many bacterial and archaeal species, represents an ancient and major new subtype of type ii secretion. the tad genes are present on a genomic island named the widespread colonization island (wci), and encode the machinery that is required for the assembly of adhesive flp (fimbrial low-molecular-weight protein) pili. the tad genes are essential for biofilm formation, colonization and pathogenesis in the genera aggregat ...200717435791
pasteurella meningo-encephalitis--a risk of household pets. 200717442396
protective immunity conferred by recombinant pasteurella multocida lipoprotein e (plpe).the genes encoding pasteurella multocida lipoprotein e (plpe) and lipoprotein b (plpb) were cloned from p. multocida strain x-73 (serotype a:1) and expressed in escherichia coli. the protective immunity conferred by recombinant plpe (r-plpe) and plpb (r-plpb) on mice and chickens was evaluated. the results showed that mice immunized with 10microg of purified r-plpe were protected (80-100% survival rate) against challenge infection with 10 or 20 ld(50) of p. multocida strains x-73 (serotype a:1), ...200717449151
successful treatment of cervical spinal epidural empyema secondary to grass awn migration in a cat.spinal epidural empyema (see) represents a severe pyogenic infection of the epidural space. clinical signs of the disease are non-specific--increased body temperature, intense neck pain, neurological signs of a transverse myelopathy--and can lead to severe and permanent neurological deficits. this report describes the diagnosis and successful surgical treatment of cervical see secondary to grass awn migration in a cat. although it is uncommon, this disease should be suspected in cats with progre ...200717449314
comparative sequence analysis of 16s rrna gene of pasteurella multocida serogroup b isolates from different animal species.the phylogenetic relationships of five isolates of pasteurella multocida serotype b:2 belonging to buffalo, cattle, pig, sheep and goat were investigated by comparative sequence analysis of 16s rrna gene. the 1468bp fragment of 16s rrna gene sequence comparison showed that the isolates of cattle (pm75), pig (pm49) and sheep (pm82) shared 99.9% homology with the buffalo isolate (vaccine strain p52) whereas, the goat isolate (pm86) shared 99.8% homology with the vaccine strain. the 16s rrna gene s ...200717459437
outer membrane protein h for protective immunity against pasteurella multocida.pasteurella multocida, a gram-negative facultative anaerobic bacterium, is a causative animal pathogen in porcine atrophic rhinitis and avian fowl cholera. for the development of recombinant subunit vaccine against p. multocida, we cloned and analyzed the gene for outer membrane protein h (omph) from a native strain of pasteurella multocida in korea. the omph had significant similarity in both primary and secondary structure with those of other serotypes. the full-length, and three short fragmen ...200717483806
crystal structures of pasteurella multocida sialyltransferase complexes with acceptor and donor analogues reveal substrate binding sites and catalytic mechanism.sialyltransferases are key enzymes involved in the biosynthesis of biologically and pathologically important sialic acid-containing molecules in nature. binary x-ray crystal structures of a multifunctional pasteurella multocida sialyltransferase (delta24pmst1) with a donor analogue cmp-3f(a)neu5ac or cmp-3f(e)neu5ac were determined at 2.0 and 1.9 a resolutions, respectively. ternary x-ray structures of the protein in complex with cmp or a donor analogue cmp-3f(a)neu5ac and an acceptor lactose ha ...200717487984
cross-reactive adaptive immune response to oral commensal bacteria results in an induction of receptor activator of nuclear factor-kappab ligand (rankl)-dependent periodontal bone resorption in a mouse model.the present study examined whether induction of an adaptive immune response to orally colonizing non-pathogenic pasteurella pneumotropica by immunization with the phylogenetically closely related bacterium, actinobacillus actinomycetemcomitans, can result in periodontal bone loss in mice.200717488448
protostrongylid parasites and pneumonia in captive and wild thinhorn sheep (ovis dalli).we describe health significance of protostrongylid parasites (parelaphostrongylus odocoilei and protostrongylus stilesi) and other respiratory pathogens in more than 50 naturally infected dall's sheep (ovis dalli dalli) from the mackenzie mountains, northwest territories (1998-2002) as well as in three stone's sheep (o. d. stonei) experimentally infected with p. odocoilei (2000-2002). histological lesions in the brain and distribution of p. odocoilei in the muscles of experimentally and naturall ...200717495303
two further cases, bacteriologically verified of human infection with "pasteurella x" (syn. yersinia enterocolitica). 1966. 200717504418
pasteurella multocida expresses two lipopolysaccharide glycoforms simultaneously, but only a single form is required for virulence: identification of two acceptor-specific heptosyl i transferases.lipopolysaccharide (lps) is a critical virulence determinant in pasteurella multocida and a major antigen responsible for host protective immunity. in other mucosal pathogens, variation in lps or lipooligosaccharide structure typically occurs in the outer core oligosaccharide regions due to phase variation. p. multocida elaborates a conserved oligosaccharide extension attached to two different, simultaneously expressed inner core structures, one containing a single phosphorylated 3-deoxy-d-manno ...200717517879
characterization of a broad range antibacterial substance from a new bacillus species isolated from amazon basin.a bacillus sp. strain producing a bacteriocin-like substance was characterized by biochemical profiling and 16s rdna sequencing. the phylogenetic analysis indicated that this strain has low sequence similarity with most bacillus spp., suggesting a new species was isolated. the antimicrobial activity was detected starting at the exponential growth phase, and maximum activity was observed at stationary phase. the substance was inhibitory to a broad range of indicator strains, including pathogenic ...200717534601
molecular characterization of avian strains of pasteurella multocida serogroup-a:1 based on amplification of repetitive regions by pcr.repetitive extragenic palindromic (rep)-pcr (polymerase chain reaction), enterobacterial repetitive intergenic consensus (eric)-pcr, and single primer pcr assays were employed to characterize 66 strains of pasteurella multocida serogroup a:1 isolated from avian species belonging to different regions of india. rep-pcr resulted in amplification of rep sequences from the genome which were in the range of approximately 200 to approximately 3000 bp and accounted for a total of 54 distinguishing profi ...200817537513
the cloning and sequencing of the udp-galactose 4-epimerase gene (gale) from avibacterium paragallinarum.the putative uridine diphosphate (udp)-galactose 4-epimerase encoding gene, gale, was isolated from avibacterium paragallinarum with the use of degenerate primers, colony hybridization and inverse pcr. the data revealed an open reading frame of 1017 bp encoding a protein of 338 amino acids with a molecular weight of 37 kda and an isoelectric point of 5.5. high sequence homology was obtained with an 87, 91 and 89% sequence identity on protein level towards the gale genes from actinobacillus pleur ...200717541831
efficacy of danofloxacin in the treatment of pneumonic pasteurellosis in specific pathogen-free lambs. 200717545648
outer membrane permeability for nonpolar antimicrobial agents underlies extreme susceptibility of pasteurella multocida to the hydrophobic biocide triclosan.pasteurella multocida exhibits nonspecific susceptibility to nonpolar antimicrobial agents such as triclosan, despite possessing an ultrastructurally typical gram-negative cell envelope. capsulated and noncapsulated cell surface variants were examined to investigate the role outer membrane permeability plays in triclosan susceptibility. test strains were unable to initiate growth in the presence of bile salts and were susceptible to triclosan with minimal inhibitory concentrations (mics) ranging ...200717560745
an investigation of the aetiological role of bovine herpesvirus 4 in bovine endometritis.uteri from 31 infertile cattle were examined for the presence of bovine herpesvirus 4 (bohv-4) by nested polymerase chain reaction (pcr). samples were also tested for bacteria, including chlamydiae and mycoplasma bovis. bohv-4 was detected by pcr in 27/31 (87.1%) samples, but the presence and amount of viral dna was not correlated with histological and bacteriological findings. arcanobacterium pyogenes, histophilus somni and pasteurella multocida were isolated from five cows with endometritis. c ...200817572123
calcineurin-independent inhibition of 3t3-l1 adipogenesis by pasteurella multocida toxin: suppression of notch1, stabilization of beta-catenin and pre-adipocyte factor 1.pasteurella multocida toxin (pmt) is a potent mitogen and a specific activator of gq-dependent signalling pathways. pmt impairs osteoblast differentiation and causes bone loss and fat reduction in vivo. we examined the effect of pmt on cell signalling pathways involved in 3t3-l1 adipocyte differentiation. we demonstrate that pmt treatment before or together with differentiation induction factors inhibits adipogenesis and prevents upregulation of important adipocyte markers - peroxisome-prolifera ...200717581254
detection of pathogenic leptospires in animals by pcr based on lipl21 and lipl32 genes.efficacy of primers capable of amplifying conserved outer membrane protein (omp) genes i.e., lipl21 and lipl32 of leptospira strains was tested for rapid and early diagnosis of the leptospirosis using a polymerase chain reaction (pcr). these omp genes were found to be conserved in various leptospiral serovars viz., canicola, pomona, icterohaemorrhagiae, pyrogenes, sejroe, grippotyphosa, ballum and tarassovi as pcr products of 561 bp and 756 bp were obtained by pcr employing lipl21 and lipl32 bas ...200717585694
staphylococcal infections in rabbit does on two industrial farms.the main reasons for culling adult rabbit does on two spanish rabbit farms were investigated for a year. the most important conditions were mastitis (33.3 per cent), followed by subcutaneous abscesses (9.9 per cent) and pyometra (8.7 per cent). staphylococcus aureus infections were the most severe problem, the organism being isolated from 69.2 per cent of infected animals. pasteurella species were more prevalent in cases of pyometra and pneumonia. two strains of s aureus were identified by using ...200717586791
immune response in mice and swine to dna vaccines derived from the pasteurella multocida toxin gene.dna vaccines were constructed with either a 5'-truncated or full-length, genetically detoxified toxin gene from pasteurella multocida and two different dna vaccine vectors, distinguished by the presence or absence of a secretion signal sequence. optimal pmt-specific antibody responses and spleen cell secretion of interferon-gamma following immunization of mice were achieved with pmm4, the construct containing a signal sequence and encoding the entire toxin. antibody responses were also induced i ...200717590484
[monitoring of infectious diseases among wild boars].sixty-seven serum samples and 43 pathological material samples from wild boars, taken in 5 regions of russia and in the kharkov region of the ukraine in 2002 to 2005 were studied. wild boars in some regions of russia were shown to be carriers of aujeszky's disease virus, porcine parvovirus, porcine circovirus type 2, lymphotropic herpesvirus-1, porcine cytomegalovirus, mycoplasma hyopneumoniae and pasteurella multocida. the classical swine fever (csf) virus genome was detected by polymerase chai ...200717601049
ompa: gating and dynamics via molecular dynamics simulations.outer membrane proteins (omps) of gram-negative bacteria have a variety of functions including passive transport, active transport, catalysis, pathogenesis and signal transduction. whilst the structures of approximately 25 omps are currently known, there is relatively little known about their dynamics in different environments. the outer membrane protein, ompa from escherichia coli has been studied extensively in different environments both experimentally and computationally, and thus provides a ...200817601489
evaluation of an indirect enzyme-linked immunosorbent assay (elisa) using recombinant toxin for detection of antibodies against pasteurella multocida toxin.to facilitate the control of progressive atrophic rhinitis (par) of swine caused by toxigenic pasteurella multocida, an enzyme-linked immunosorbent assay (elisa) and a serum neutralization test (nt) have recently been developed to detect antibodies against the p. multocida dermonecrotic toxin (pmdnt). however, the nt is a cumbersome and time-consuming technique. to overcome these drawbacks, we developed an indirect elisa, using recombinant pmdnt expressed in escherichia coli, for the detection o ...200717611352
nucleoside analogues are activated by bacterial deoxyribonucleoside kinases in a species-specific manner.to investigate the bactericidal activity of antiviral and anticancer nucleoside analogues against a variety of pathogenic bacteria and characterize the activating enzymes, deoxyribonucleoside kinases (dnks).200717615154
clinical and in vitro efficacy of amoxicillin against bacteria associated with feline skin wounds and abscesses.a clinical trial involving 122 cats with infected skin wounds or abscesses presented to 10 veterinary clinics was conducted to evaluate the efficacy of 2 oral amoxicillin drug products (a paste and a suspension). a 2nd objective of the study was to identify bacteria involved in such infections and verify their in vitro sensitivity to amoxicillin. samples of wound exudate were harvested at the time of presentation and submitted for aerobic and anaerobic culture. the sensitivity to amoxicillin of ...200717616057
expression of the dermonecrotic toxin by bordetella bronchiseptica is not necessary for predisposing to infection with toxigenic pasteurella multocida.this experiment was designed to determine whether a bordetella bronchiseptica mutant that does not produce dermonecrotic toxin (dnt) is still capable of predisposing pigs to infection with toxigenic pasteurella multocida. three groups of pigs were initially inoculated intranasally with a wild type b. bronchiseptica that produces dnt, an isogenic mutant of b. bronchiseptica that does not produce dnt, or pbs. all pigs were then challenged intranasally with a toxigenic strain of p. multocida 4 days ...200717624695
chemoenzymatic synthesis with distinct pasteurella heparosan synthases: monodisperse polymers and unnatural structures.heparosan (-glcua-beta1,4-glcnac-alpha1,4-)(n) is a member of the glycosaminoglycan polysaccharide family found in the capsule of certain pathogenic bacteria as well as the precursor for the vertebrate polymers, heparin and heparan sulfate. the two heparosan synthases from the gram-negative bacteria pasteurella multocida, pmhs1 and pmhs2, were efficiently expressed and purified using maltose-binding protein fusion constructs. these relatively homologous synthases displayed distinct catalytic cha ...200717627940
experimental study of pathogenicity of pasteurella multocida serogroup f in rabbits.the role of pasteurella multocida serogroup f in inducing disease in rabbits was investigated in this study. three groups of 12 pasteurella-free rabbits each were intranasally (i.n.), subcutaneously (s.c.), and perorally (p.o.) challenged, respectively. six rabbits of each group were immunosuppressed using dexamethasone. eight rabbits (four of them immunosuppressed) inoculated i.n. showed symptoms of respiratory distress resulting in respiratory failure and died or were euthanized in the termina ...200817629636
occurrence of antimicrobial resistance in bacteria from diagnostic samples from dogs.to study the occurrence of antimicrobial resistance among common bacterial pathogens from dogs and relate resistance patterns to data on consumption of antimicrobials.200717644533
shipping fever: i. search for a hypothetical agent associated with pasteurella. 194417648039
rhinitis of swine. vii. production of lesions in pigs and rabbits with a pure culture of pasteurella multocida. 195317648630
rhinitis of swine. viii. experiments with pasteurella multocida. 195317648676
dissociation and virulence in strains of pasteurella multocida isolated from a variety of lesions. 195317648678
a herd outbreak of mastitis caused by pasteurella multocida. 195417648709
complement-fixation tests of swine serum ii. in the demonstration of pasteurella multocida antibodies in experimentally produced rhinitis. 195517648843
bovine mastitis caused by pasteurella haemolytica: a case report. 195517648849
studies on pneumnia of cattle. i. experimental infection of calves with pasteurella haemolytica. 195617648917
further observations on typing pasteurella multocida by the indirect hemagglutination test. 196217649399
epizootiologic studies of shipping fever of cattle: i. the microbial agents isolated.nineteen strains of pasteurella spp., but no viruses cytopathogenic for bovine embryonic kidney cells were isolated from pneumonic lesions present in "normal" veal calves at slaughter. in studies on two herds of native cattle and six lots of western feeder calves, pasteurella spp. were isolated from nasal swabs from healthy cattle and those with shipping fever. viruses of the psittacosis-lymphogranuloma group were isolated from nasal swabs from animals in five groups. viruses provisionally ident ...196417649487
production of antibody in mammary gland of pregnant, non-lactating and lactating cows, evoked by polyvalent antigen with reference to dosage and frequency of immunization.sixteen cows were used in a series of experiments to test dose, route and frequency responses in the production of milk and serum agglutinins to a spectrum of 9 proven bovine pathogens. the bacterial species were: pasteurella multocida (2 isolates), escherichia coli, staphylococcus aureus, staphylococcus albus, streptococcus sp., corynebacterium sp., salmonella enteriditis, and aerobacter aerogenes. primary immunizations were made either through the teat canal or intramuscularly. "booster" injec ...196417649521
invasive pasteurella multocida sinusitis in a renal transplant patient.pasteurella are commensal gram-negative bacteria isolated from the oral cavity of many domesticated animals. most human infections occur post animal bite or scratch injury resulting in local cutaneous infection; however, case reports suggest that transmission may occur via animal secretions. pasteurella species can be associated with serious systemic infections particularly in those with underlying disease and in the immunocompromised. we present a case of invasive pasteurella multocida sinusiti ...200817655653
biochemical characterization of a neisseria meningitidis polysialyltransferase reveals novel functional motifs in bacterial sialyltransferases.the extracellular polysaccharide capsule is an essential virulence factor of neisseria meningitidis, a leading cause of severe bacterial meningitis and sepsis. serogroup b strains, the primary disease causing isolates in europe and america, are encapsulated in alpha-2,8 polysialic acid (polysia). the capsular polymer is synthesized from activated sialic acid by action of a membrane-associated polysialyltransferase (nmb-polyst). here we present a comprehensive characterization of nmb-polyst. diff ...200717662040
pcr analysis of pasteurella multocida isolates from an outbreak of pasteurellosis in indian pigs.an outbreak of pasteurellosis with high mortality was recorded in indigenous pigs in india. the presence of pasteurella multocida in samples collected from dead pigs was detected by smear examination and isolation, and later by p. multocida specific polymerase chain reaction (pm-pcr). p. multocida was detected in all the samples collected from dead pigs, with nine strains ultimately isolated. all the isolates were positive by pm-pcr. six isolates showed capa and three were of capd capsular types ...200817669491
action of pasteurella multocida toxin on galpha(q) is persistent and independent of interaction with g-protein-coupled receptors.pasteurella multocida toxin (pmt) activates galpha(q) and facilitates stimulation of inositol phosphate accumulation induced by agonists via g(q)-coupled membrane receptors. here, we studied the effects of pmt on agonist-induced gtpgammas binding to g(q) in cell membranes and a role of g-protein-coupled receptors in the action of pmt. pre-treatment of swiss 3t3 cells with pmt increased bombesin or vasopressin-induced gtpgammas-binding in cell membranes by about 50 to 150%. increase in agonist-st ...200717669624
purification, crystallization and preliminary crystallographic characterization of the alpha 2,6-sialyltransferase from photobacterium sp. jt-ish-224.sialyltransferases transfer sialic acid from cytidine-5-monophospho-n-acetylneuraminic acid (cmp-neuac) to the nonreducing termini of the oligosaccharyl structures of various glycoproteins and glycolipids. the newly cloned alpha2,6-sialyltransferase from photobacterium sp. jt-ish-224 (from the vibrionaceae family) is composed of two domains: an unknown n-terminal domain and a catalytic c-terminal domain which shares significant homology with the pasteurella multocida multifunctional sialyltransf ...200717671362
variation in the molecular weight of photobacterium damselae subsp. piscicida antigens when cultured under different conditions in vitro.the antigenicity of photobacterium damselae (ph. d.) subsp. piscicida, cultured in four different growth media [tryptone soya broth (tsb), glucose-rich medium (grm), iron-depleted tsb (tsb + ir(-)), and iron-depleted grm (grm + ir(-))] was compared by enzyme-linked immunosorbent assay (elisa) and western blot analysis using sera obtained from sea bass (dicentrarchus labrax) raised against live or heat-killed ph. d. subsp. piscicida. the antigenic expression of ph. d. subsp. piscicida was found t ...200717679772
[severe pasteurella multocida pneumonia by close contact with a pet in chronic respiratory failure]. 200717682434
pasteurella multocida septic shock following liver transplantation treated with drotrecogin alpha (activated).severe sepsis and progression to septic shock in solid organ transplant recipients is associated with a high mortality. we describe a fulminant case of septic shock in a liver transplant recipient caused by pasteurella multocida, a gram-negative coccobacillus most commonly associated with domestic cats and dogs. p. multocida is a rare cause of bacteremia and has not been reported as a cause of septic shock following liver transplantation. in addition to standard therapy, the patient was managed ...200717692071
[knee prosthesis infection due to pasteurella multocida]. 200717692220
peritonitis associated with pasteurella multocida in peritoneal dialysis patients--case report and review of the literature.pasteurella multocida is a zoonotic pathogen found in the oral cavities of domestic dogs and cats and other wild and domestic animals. 14 cases ofperitoneal dialysis-associated pasteurella multocida peritonitis linked to animal contact have been reported in the literature to date. in each case, the source of infection was believed to be a domestic cat or cats. one case of spontaneous bacterial peritonitis has been reported in a cirrhotic patient and was not linked to animal contact. poor hygiene ...200717703837
nucleotide sequence and transfer properties of two novel types of actinobacillus pleuropneumoniae plasmids carrying the tetracycline resistance gene tet(h).to analyse the sequence and transfer properties of two tetracycline resistance plasmids found in clinical isolates of actinobacillus pleuropneumoniae in order to assess their role in the spread of tetracycline resistance.200717704116
decoration of pasteurella multocida lipopolysaccharide with phosphocholine is important for virulence.phosphocholine (pcho) is an important substituent of surface structures expressed by a number of bacterial pathogens. its role in virulence has been investigated in several species, in which it has been shown to play a role in bacterial adhesion to mucosal surfaces, in resistance to antimicrobial peptides, or in sensitivity to complement-mediated killing. the lipopolysaccharide (lps) structure of pasteurella multocida strain pm70, whose genome sequence is known, has recently been determined and ...200717704225
recombinant synthesis of hyaluronan by agrobacterium sp.hyaluronan (ha) is a sugar polymer of a repeating disaccharide, beta1-3 d-n-acetylglucosamine (glcnac) beta1-4 d-glucuronic acid (glca). it finds applications in numerous biomedical procedures such as ophthalmic surgery and osteoarthritis treatment. until recently, the only commercial sources were extraction of rooster combs and from fermentation of pathogenic streptococcus. in this work, we demonstrate that metabolic engineering strategies enable the recombinant synthesis of hyaluronan in a saf ...200717705506
contamination of post-endoscopic sinus surgery sinus cavities with pasteurella multocida. 200717711761
pasteurella multocida sepsis and meningitis in 2-month-old twin infants after household exposure to a slaughtered sheep.this article outlines 2 cases of pasteurella multocida sepsis and meningitis in 2-month-old twins after their father was exposed to a sheep during a sacrifice celebration at home. these cases emphasize the necessity of respecting basic hygiene rules and the danger involved in animal sacrifice without suitable professional structure.200717712748
direct isolation of pasteurella-like microorganisms from brains of horses suffering from so-called cornstalk disease. 193517769435
a pasteurella-like microorganism in the brains of horses suffering from so-called cornstalk disease. 193517783624
[pasteurella multocida meningitis: zoonosis by pets]. 200717802726
please, do not forget pasteurella multocida. 200717806067
pasteurella pestis: role of pesticin i and iron in experimental plague.loss of the genetic determinant for pesticin i in pasteurella pestis results in concomitant loss of the plague coagulase and fibrinolytic factor. the median lethal dose for mice of an isolate lacking only these activities is increased by factors of about 10(1), 10(4), and 10(7) cells when administered by the intravenous, intraperitoneal, and subcutaneous routes, respectively. virulence of the aforesaid strain can be enhanced in mice treated with 40 microg of ferrous iron. this response resembles ...196517809405
comparison of the in vitro susceptibility of rodent isolates of pseudomonas aeruginosa and pasteurella pneumotropica to enrofloxacin.the objectives of this study were to determine and compare the in vitro enrofloxacin susceptibility of 94 pseudomonas aeruginosa isolates obtained from enrofloxacin-treated and untreated mice and that of 40 pasteurella pneumotropica strains and also to assess the efficacy and effects of enrofloxacin treatment of laboratory mice. the minimum inhibitory concentrations (mics) of enrofloxacin against all the ps. aeruginosa isolates were in the range of 1 to 4 microg/ml, whereas those against all the ...200717823403
sinonasal plasmacytoma in a cat.a 13-year-old female spayed domestic shorthair cat presented with a history of right-sided mucopurulent nasal discharge for 18 months. computed tomography revealed a mass within the right nasal cavity and the right frontal sinus. the animal was euthanized, and a postmortem examination was performed. on macroscopic examination, the right nasal cavity and the right frontal sinus were partially occluded by a soft whitish mass. microscopically, the mass was composed of well-differentiated plasma cel ...200717823407
immunological roles of pasteurella multocida toxin (pmt) using a pmt mutant strain.the immunological role of the pasteurella multocida toxin (pmt) in mice was examined using a pmt mutant strain. after a nasal inoculation, the mutant strain failed to induce interstitial pneumonia. moreover, pmt had no significant effect on the populations of cd4+, cd8+, cd3+, and cd19+ immunocytes in blood or on the populations of cd4+ and cd8+ splenocytes (p<0.01). however, there was a significant increase in the total number of cells in the bal samples obtained from the wild-type p. multocida ...200717846592
evaluation of goose serum amyloid a acute phase response by enzyme-linked immunosorbent assay.serum amyloid a (saa) is of interest as the circulating precursor of amyloid a protein, the fibrillar component of aa (secondary) amyloid deposits, and also as an extremely sensitive and rapid major acute phase protein. serum concentrations of acute phase proteins (apps) provide valuable information about the diagnosis and prognosis of various diseases, and thus the relevance of apps for monitoring the health status of domestic animals is widely accepted. more importantly, the measurement of saa ...200717867462
safety and protective efficacy of intramuscular vaccination with a live aroa derivative of pasteurella multocida b:2 against experimental hemorrhagic septicemia in calves.three groups of five calves, namely, v1, v2, and v3, were immunized intramuscularly at 4 and 8 weeks of age with ca. 10(9), 10(8), and 10(7) cfu, respectively, of a derivative of pasteurella multocida b:2 wild-type strain 85020 containing a deletion in the aroa gene (strain jrmt12). the first and second vaccinations resulted in significantly (p < 0.01) higher rectal temperature responses in groups v1 and v2 than in group v3. serum immunoglobulin m (igm) and igg titers did not increase in any gro ...200717875632
a multidomain outer membrane protein from pasteurella multocida: modelling and simulation studies of pmompa.pmompa is a two-domain outer membrane protein from pasteurella multocida. the n-terminal domain of pmompa is a homologue of the transmembrane beta-barrel domain of ompa from escherichia coli, whilst the c-terminal domain of pmompa is a homologue of the extra-membrane neisseria meningitidis rmpm c-terminal domain. this enables a model of a complete two domain pmompa to be constructed and its conformational dynamics explored via md simulations of the protein embedded within two different phospholi ...200717888868
inhibition of trpc5 channels by intracellular atp.trpc5 channels are ca(2+)-permeable nonselective cation channels activated by g-protein-coupled receptors, although the mechanisms responsible for channel activation and regulation are poorly understood. carbachol-activated trpc5 currents were recorded by the whole-cell patch clamp technique from human embryonic kidney 293 cells transiently transfected with trpc5 and the m1 muscarinic receptor. some published studies of trpc5 currents have included atp and/or gtp in the patch pipette, whereas ot ...200817925457
dna fingerprinting analysis of breakthrough outbreaks in vaccine-protected poultry stocks.we report recurrent outbreaks of yersinia pseudotuberculosis conjunctivitis in ducks and of fowl cholera in geese, occurring in stocks previously vaccinated with inactivated autogenous vaccines. enterobacterial repetitive intergenic consensus sequence-based pcr and pulsed-field gel electrophoresis indicated reinfection with a new y. pseudotuberculosis strain and vaccine evasion by the same pasteurella multocida strain.200717928428
susceptibility of bacterial pathogens against lincomycin/spectinomycin (1/2), penicillin g/neomycin (1/1), and penicillin g/dihydrostreptomycin (1/1) as determined in the bft-germvet monitoring program 2004-2006.a total of 368 bacterial pathogens, including 72 coagulase-positive and coagulase-variable staphylococci, 97 beta-haemolytic streptococci, 51 escherichia coli, 75 pasteurella multocida, 25 mannheimia haemolytica, 25 pseudomonas aeruginosa, and 23 arcanobacterium pyogenes, were investigated for their susceptibility to the three combinations of antimicrobial agents lincomycin/spectinomycin (1/2), penicillin g/neomycin (1/1), and penicillin g/dihydrostreptomycin (1/1) in comparison to their suscept ...200717939451
antimicrobial susceptibility of pasteurella multocida and bordetella bronchiseptica from dogs and cats as determined in the bft-germvet monitoring program 2004-2006.a total of 92 canine/feline pasteurella multocida strains form respiratory tract infections or infections of skin/ear/mouth as well as 42 canine/feline bordetella bronchiseptica strains from respiratory tract infections were investigated for their susceptibility to antimicrobial agents. while the p. multocida strains were susceptible to all antimicrobial agents tested - except sulfonamides -, a considerable number of the b. bronchiseptica strains was resistant or exhibited high mic values agains ...200717939457
quantitative resistance level (mic) of pasteurella multocida isolated from pigs between 2004 and 2006: national resistance monitoring by the bvl.the national resistance monitoring of the federal office of consumer protection and food safety (bvl) is to determine the prevalence of resistance of bacterial pathogens from animals using a valid database. from 2004 to 2006, a total of 1,472 pasteurella multocida strains isolated from pigs with acute respiratory tract diseases was submitted to the bvl and examined. of these, 1,11 (75.5 %) were included in the study and tested using 24 different antimicrobial substances. the results showed that ...200717939459
quantitative resistance level (mic) of bacterial pathogens (escherichia coli, pasteurella multocida, pseudomonas aeruginosa, salmonella sp., staphylococcus aureus) isolated from chickens and turkeys: national resistance monitoring by the bvl 2004/2005.in the study 2004/2005, the current quantitative resistance level of escherichia coli, pasteurella multocida, pseudomonas aeruginosa, salmonella sp. and staphylococcus aureus from chickens and turkeys was determined for the first time within the framework of the national resistance monitoring of the federal office of consumer protection and food safety (bvl). the objective was to implement a valid database on the basis of which the development and spread of resistance can be evaluated and monito ...200717939460
reversible myocardial depression associated with sepsis in a dog. 200717939574
accuracy of susceptibility testing of pasteurella multocida and mannheimia haemolytica.the accuracy of antimicrobial susceptibility determinations relies on the bacterial species identification and the test methodology that is being used. in the present study, both aspects were investigated for 141 pasteurella multocida and 34 mannheimia haemolytica sensu lato isolates recovered from the upper respiratory tract of healthy calves. this was performed on the one hand by comparing of classical phenotyping with tdna-pcr genotyping and on the other hand by pairwise comparison of disk di ...200717949308
pasteurella multocida bacteremia in asymptomatic plateletpheresis donors: a tale of two cats.bacterial contamination of platelet (plt) concentrates occurs in 1 in 1000 to 1 in 3000 components and has been a leading cause of transfusion-associated morbidity and mortality. two cases of pasteurella multocida bacteremia in asymptomatic plateletpheresis donors are reported. clinical outcomes were profoundly different, emphasizing the importance of robust methods to detect bacterial contamination.200717958526
shuffling of pig interleukin-2 gene and its enhancing of immunity in mice to pasteurella multocida vaccine.in order to explore the safe and effective adjuvant for promotion of immunity of animals against infection, the experiment was carried out to shuffle tibet pig il-2 cdna with other il-2 cdna from human, yak and mouse, and the effect of shuffled il-2 (il-2s) gene in vivo was investigated on immunity of mice to pasteurella multocida. the il-2s protein was found to remarkably promote the proliferation of pig lymphoblasts than the native pig il-2 protein. then the il-2s gene was cloned into vr1020 e ...200717959278
n-acetylcysteine stimulates osteoblastic differentiation of mouse calvarial cells.estrogen deficiency causes osteoporosis via increased generation of reactive oxygen species (ros), and thus, antioxidants may prove to be the effective therapeutic candidates. we examined the effects of the antioxidant n-acetylcysteine (nac) on osteoblastic differentiation in mouse calvarial cells. nac (10-30 mm) enhanced alkaline phosphatase activity, mrna expression of osteoblast differentiation-associated genes and mineralized nodule formation. it also increased expression of bone morphogenet ...200817979115
pasteurella multocida infections: i. pasteurella multocida infection due to animal bite. 197018018289
the bacteriology and antimicrobial susceptibility of infected and non-infected dog bite wounds: fifty cases.dog bite wounds are a common reason for dogs requiring veterinary care, but there is surprisingly little data on the bacteriology of bite wounds. a prospective study was performed on dogs with various grades of bite wound to identify the bacteria present in these wounds. swabs were collected from all wounds for bacterial culture and cytology. all swabs were cultured aerobically and anaerobically and all aerobic cultures were evaluated for antibiotic susceptibility using the kirby bauer disk diff ...200818029118
pasteurella multocida infections. 200718055649
diagnostic and typing options for investigating diseases associated with pasteurella multocida.pasteurella multocida is responsible for major animal diseases of economic significance in both developed and developing countries whereas human infections related to this bacterium are infrequent. significantly, development of a carrier status or latent infections plays a critical role in the epidemiology of these diseases. aiming at increased knowledge of these infections, we examine potential diagnostic and selected typing systems for investigating diseases caused by p. multocida. detection o ...200818061377
[frequency of occurrence of pneumonia associated agents and their correlation with clinical and pathological-anatomical findings in pigs].the aim of this study was to investigate the incidence and influence of different causative organisms involved in the development of pneumonia and bronchopneumonia in pigs. bronchoalveolar lavage fluid (balf) from 339 pigs was examined molecular-biologically and culturally. the evaluation considered the following pathogens: mycoplasma (m.) hyopneumoniae, mycoplasma (m.) hyorhinis, prrsv (us-type), prrsv (eu-type), pcv-2, influenzavirus type a, alpha-haemolytic streptococci, beta-haemolytic strep ...200718085159
diagnosis | pasteurellosis. 200818094697
[pasteurella multocida pneumonia with molecular evidence of zoonotic transmission].we report the case of a patient with pneumonia caused by pasteurella multocida (p. multocida). an 83-year-old woman admitted for bronchiectasis, productive cough, and a high fever was found in chest radiography on admission to have a new infiltrative shadow in the left lower lung field. chest computed tomography indicated bilateral bronchiectasis and an infiltrative lingular shadow. p. multocida was isolated from sputum samples. biapenem and minocycline therapy ameliorated symptoms. pulsed-field ...200718095473
alteration of pasteurella pestis bacteriophage following successive transfer on pasteurella pseudotuberculosis and on shigellae. 194818102208
pneumonia in sheep associated with infection by a pasteurella-like organism. 194918113406
[not available]. 194918115139
[not available]. 194918115140
twenty-five year survival of a pasteurella pestis culture without transfer. 194918124445
fowl cholera; pasteurella multocida. 194918124873
[not available]. 194918129464
the behavior of pasteurella pestis in glycerin and rhamnose mediums. 194918132375
[pasteurella pseudotuberculosis sepsis]. 194918139494
relationship of catalase activity to virulence in pasteurella pestis. 194918145415
novel adhesin from pasteurella multocida that binds to the integrin-binding fibronectin fniii9-10 repeats.phage display screening with fragmented genomic dna from the animal pathogen pasteurella multocida has identified a gene encoding a putative fibronectin binding protein (19). homologues of this gene (pm1665) are found in all other sequenced members of the pasteurellaceae. gene pm1665 has been cloned, and the protein has been expressed. recombinant pm1665 protein binds to both soluble and immobilized fibronectin and is unique in that it interacts with the integrin-binding fibronectin type iii (fn ...200818160478
cat got your tongue? 200818171232
effect of vaccinating lambs against pneumonic pasteurellosis under new zealand field conditions on their weight gain and pneumonic lung lesions at slaughter.in a field trial, 9174 lambs from seven commercial sheep flocks with a history of subclinical pneumonia were either vaccinated with ovipast plus (intervet) or given a placebo by systematic random allocation; they were vaccinated twice at an interval of four to six weeks and grazed on pasture in the same paddocks. they were weighed at the first vaccination, 11 and 23 weeks later, and one to three days before they were slaughtered. the extent of the pneumonic lesions in their lungs was scored visu ...200818178931
Refresh
firstprev
...71727374757677
nextlast
Displaying items 7001 - 7100 of 7610